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Tytuł:
TGF-β Isoforms and GDF-15 in the Development and Progression of Atherosclerosis.
Autorzy:
Liuizė Abramavičiūtė A; Department of Biochemistry, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
Mongirdienė A; Department of Biochemistry, Medical Academy, Lithuanian University of Health Sciences, LT-50161 Kaunas, Lithuania.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 09; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Atherosclerosis*/metabolism
Growth Differentiation Factor 15*/metabolism
Transforming Growth Factor beta*/metabolism
Humans ; Inflammation/metabolism ; Macrophages/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system.
Autorzy:
Asundi J; Calico Life Sciences LLC, South San Francisco, California, USA.
Zhang C; Calico Life Sciences LLC, South San Francisco, California, USA.
Donnelly-Roberts D; AbbVie, North Chicago, Illinois, USA.
Solorio JZ; Calico Life Sciences LLC, South San Francisco, California, USA.
Challagundla M; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
Connelly C; Calico Life Sciences LLC, South San Francisco, California, USA.
Boch C; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
Chen J; AbbVie, North Chicago, Illinois, USA.
Richter M; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
Maneshi MM; AbbVie, North Chicago, Illinois, USA.
Swensen AM; AbbVie, North Chicago, Illinois, USA.
Lebon L; Calico Life Sciences LLC, South San Francisco, California, USA.
Schiffmann R; Texas Christian University, Fort Worth, Texas, USA.
Sanyal S; Calico Life Sciences LLC, South San Francisco, California, USA.
Sidrauski C; Calico Life Sciences LLC, South San Francisco, California, USA.
Kolumam G; Calico Life Sciences LLC, South San Francisco, California, USA.
Baruch A; Calico Life Sciences LLC, South San Francisco, California, USA.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Feb; Vol. 30 (2), pp. e14600.
Typ publikacji:
Journal Article
MeSH Terms:
Growth Differentiation Factor 15*/genetics
Leukoencephalopathies*/genetics
Humans ; Mice ; Animals ; Central Nervous System/metabolism ; Eukaryotic Initiation Factor-2B/genetics ; Eukaryotic Initiation Factor-2B/metabolism ; Biomarkers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF15 Modulates the Zoledronic-Acid-Induced Hyperinflammatory Mechanoresponse of Periodontal Ligament Fibroblasts.
Autorzy:
Nitzsche A; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Hennig CL; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
von Brandenstein K; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Döding A; Section of Geriodontics, Department of Conservative Dentistry and Periodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Schulze-Späte U; Section of Geriodontics, Department of Conservative Dentistry and Periodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Symmank J; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Jacobs C; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
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Źródło:
Cells [Cells] 2024 Jan 12; Vol. 13 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Growth Differentiation Factor 15*/metabolism
Periodontal Ligament*/drug effects
Periodontal Ligament*/metabolism
Zoledronic Acid*/pharmacology
Humans ; Fibroblasts ; Interleukin-6 ; Osteogenesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.
Autorzy:
Xie B; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tang W; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wen S; Department of Emergency Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Chen F; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yang C; Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Wang M; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Yang Y; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Liang W; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.; Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Dec 27; Vol. 14 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Growth Differentiation Factor 15*/pharmacology
Platelet Aggregation*/genetics
Proto-Oncogene Proteins c-ret*
Glial Cell Line-Derived Neurotrophic Factor Receptors*/metabolism
Humans ; Adenosine Diphosphate/pharmacology ; ErbB Receptors ; Extracellular Signal-Regulated MAP Kinases ; Proto-Oncogene Proteins c-akt ; Transforming Growth Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF15 Promotes the Osteogenic Cell Fate of Periodontal Ligament Fibroblasts, thus Affecting Their Mechanobiological Response.
Autorzy:
Lösch L; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Stemmler A; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Fischer A; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Steinmetz J; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Schuldt L; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Hennig CL; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Symmank J; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
Jacobs C; Department of Orthodontics, University Hospital Jena, Leutragraben 3, 07743 Jena, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 11; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 11.
Typ publikacji:
Journal Article
MeSH Terms:
Periodontal Ligament*
Growth Differentiation Factor 15*/genetics
Growth Differentiation Factor 15*/metabolism
Humans ; Cells, Cultured ; Cell Differentiation ; Fibroblasts/metabolism ; Inflammation/metabolism ; Tooth Movement Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming.
Autorzy:
Ray N; Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Pusan National University, Yangsan, Korea.
Park SJ; Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Pusan National University, Yangsan, Korea.
Jung H; Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Pusan National University, Yangsan, Korea.
Kim J; Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Pusan National University, Yangsan, Korea.
Korcsmaros T; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK.; Earlham Institute, Norwich Research Park, Norwich, UK.; Quadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Moon Y; Laboratory of Mucosal Exposome and Biomodulation, Department of Integrative Biomedical Sciences, Pusan National University, Yangsan, Korea. .; Earlham Institute, Norwich Research Park, Norwich, UK. .; Graduate Program of Genomic Data Sciences, Pusan National University, Yangsan, Korea. .
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Źródło:
Communications biology [Commun Biol] 2023 Jun 03; Vol. 6 (1), pp. 602. Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Growth Differentiation Factor 15*/genetics
Growth Differentiation Factor 15*/metabolism
Microbiota*
Mice ; Animals ; Up-Regulation ; Biomarkers ; Autophagy ; Mucins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling.
Autorzy:
Li W; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Li W; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Zhang W; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Wang H; Department of Orthopedics, Taizhou People's Hospital, Taizhou, 225300, China.
Yu L; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Yang P; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Qin Y; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Gan M; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Yang X; Orthopedics and Sports Medicine Center, The Affiliated Suzhou Hospital of Nanjing Medical University, 242 Guangji Road, Suzhou, 215006, China.
Huang L; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China.
Hao Y; Orthopedics and Sports Medicine Center, The Affiliated Suzhou Hospital of Nanjing Medical University, 242 Guangji Road, Suzhou, 215006, China. .
Geng D; Department of Orthopedics, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, China. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Jul 03; Vol. 14 (1), pp. 171. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Femur Head Necrosis*/chemically induced
Ferroptosis*
Growth Differentiation Factor 15*/genetics
Melatonin*/therapeutic use
Animals ; Rats ; Femur Head/pathology ; Glucocorticoids/adverse effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Different Kinetics of Serum ADAMTS13, GDF-15, and Neutrophil Gelatinase-Associated Lipocalin in the Early Phase of Aneurysmal Subarachnoid Hemorrhage.
Autorzy:
Csecsei P; Department of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.
Olah C; Neurosurgical Unit, B.A.Z. County Hospital, 3526 Miskolc, Hungary.
Varnai R; Department of Primary Health Care, Medical School, University of Pecs, 7624 Pecs, Hungary.
Simon D; Department of Immunology and Biotechnology, Medical School, University of Pecs, 7624 Pecs, Hungary.
Erdo-Bonyar S; Department of Immunology and Biotechnology, Medical School, University of Pecs, 7624 Pecs, Hungary.
Berki T; Department of Immunology and Biotechnology, Medical School, University of Pecs, 7624 Pecs, Hungary.
Czabajszki M; Neurosurgical Unit, B.A.Z. County Hospital, 3526 Miskolc, Hungary.
Zavori L; Emergency Department, Saudi German Hospital, Dubai 391093, United Arab Emirates.
Schwarcz A; Department of Neurosurgery, Medical School, University of Pecs, 7624 Pecs, Hungary.
Molnar T; Department of Anaesthesiology and Intensive Care, Medical School, University of Pecs, 7624 Pecs, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 02; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 02.
Typ publikacji:
Journal Article
MeSH Terms:
Growth Differentiation Factor 15*
Subarachnoid Hemorrhage*/complications
Humans ; Lipocalin-2 ; Kinetics ; Hospitalization ; ADAMTS13 Protein
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GDF-15 Is Associated with Poor Physical Function in Prefrail Older Adults with Diabetes.
Autorzy:
Merchant RA; Division of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chan YH; Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Duque G; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Geriatric Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.
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Źródło:
Journal of diabetes research [J Diabetes Res] 2023 Apr 28; Vol. 2023, pp. 2519128. Date of Electronic Publication: 2023 Apr 28 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Growth Differentiation Factor 15*
Diabetes Mellitus*
Humans ; Aged ; Hand Strength ; Cross-Sectional Studies ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Altered circulating GDF-15 level predicts sex hormone imbalance in males with major depressive disorder.
Autorzy:
Li Y; Eye Central, Renmin Hospital of Wuhan University, Wuhan, China.
Mei T; Nursing Department, Wuhan No.1 Hospital, Wuhan, China.
Sun T; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, China.
Xiao X; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, China. .
Peng R; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 Jan 12; Vol. 23 (1), pp. 28. Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depressive Disorder, Major*
Growth Differentiation Factor 15*/blood
Humans ; Male ; Biomarkers ; Estradiol ; Gonadal Steroid Hormones ; Testosterone
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Depletion of growth differentiation factor 15 (GDF15) leads to mitochondrial dysfunction and premature senescence in human dermal fibroblasts.
Autorzy:
Wedel S; Institute for Biochemical Aging Research, University of Innsbruck, Innsbruck, Austria.; Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
Martic I; Institute for Biochemical Aging Research, University of Innsbruck, Innsbruck, Austria.; Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
Guerrero Navarro L; Institute for Biochemical Aging Research, University of Innsbruck, Innsbruck, Austria.; Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
Ploner C; Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Pierer G; Department of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Jansen-Dürr P; Institute for Biochemical Aging Research, University of Innsbruck, Innsbruck, Austria.; Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
Cavinato M; Institute for Biochemical Aging Research, University of Innsbruck, Innsbruck, Austria.; Center for Molecular Biosciences Innsbruck (CMBI), Innsbruck, Austria.
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Źródło:
Aging cell [Aging Cell] 2023 Jan; Vol. 22 (1), pp. e13752. Date of Electronic Publication: 2022 Dec 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Growth Differentiation Factor 15*/genetics
Growth Differentiation Factor 15*/metabolism
Skin*/metabolism
Humans ; Fibroblasts/metabolism ; Mitochondria/metabolism ; Cellular Senescence/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical Value of Growth Differentiation Factor 15 Detection in the Diagnosis of Early Liver Cancer Based on Data Mining.
Autorzy:
Guo H; Center of Laboratory Test, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Liu Q; Clinical Laboratory, Guang'anmen Hospital China Academy of Chinese Medical Sciences, Beijing 100053, China.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Nov 17; Vol. 2022, pp. 4448075. Date of Electronic Publication: 2022 Nov 17 (Print Publication: 2022).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Growth Differentiation Factor 15*
Liver Neoplasms*/diagnosis
Humans ; Prognosis ; Data Mining ; Biomarkers, Tumor
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Growth Differentiation Factor-15 as a Candidate Biomarker in Gynecologic Malignancies: A Meta-analysis.
Autorzy:
Roy D; Department of Biochemistry, AIIMS, Jodhpur, India.
Modi A; Department of Biochemistry, AIIMS, Jodhpur, India.
Purohit P; Department of Biochemistry, AIIMS, Jodhpur, India.
Khokhar M; Department of Biochemistry, AIIMS, Jodhpur, India.
Goyal M; Department of Obstetrics & Gynaecology, AIIMS, Jodhpur, India.
Sharma S; Department of Biochemistry, AIIMS, Jodhpur, India.
Setia P; Department of Forensic Medicine & Toxicology, AIIMS, Jodhpur, India.
Facciorusso A; Gastroenterology Unit, Department of Medical Sciences, University of Foggia, Foggia, Italy.
Sharma P; Department of Biochemistry, AIIMS, Jodhpur, India.
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Źródło:
Cancer investigation [Cancer Invest] 2022 Nov; Vol. 40 (10), pp. 901-910. Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Growth Differentiation Factor 15*
Genital Neoplasms, Female*/diagnosis
Humans ; Female ; Biomarkers ; Odds Ratio
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Growth differentiation factor 15 is not associated with glycemic control in patients with type 2 diabetes mellitus treated with metformin: a post-hoc analysis of AIM study.
Autorzy:
Gao F; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Li C; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Wang Y; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Lu J; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Lu W; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Zhou J; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China.
Yin J; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China. .
Ma X; Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, 600 Yishan Road, Shanghai, 200233, China. .
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Źródło:
BMC endocrine disorders [BMC Endocr Disord] 2022 Oct 22; Vol. 22 (1), pp. 256. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/blood
Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/genetics
Diabetes Mellitus, Type 2*/metabolism
Growth Differentiation Factor 15*/genetics
Growth Differentiation Factor 15*/metabolism
Hypoglycemic Agents*/therapeutic use
Metformin*/therapeutic use
Humans ; Acarbose/therapeutic use ; Blood Glucose/analysis ; Glycated Hemoglobin/analysis ; Glycemic Control ; Insulin/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Cytokine Growth Differentiation Factor-15 and Skeletal Muscle Health: Portrait of an Emerging Widely Applicable Disease Biomarker.
Autorzy:
De Paepe B; Neuromuscular Reference Center, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 29; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Growth Differentiation Factor 15*/metabolism
Muscle, Skeletal*/metabolism
Muscle, Skeletal*/pathology
Humans ; Biomarkers ; Cytokines/metabolism ; Transforming Growth Factor beta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines.
Autorzy:
Haraguchi-Suzuki K; Intensive Care Unit, Gunma University Hospital, 3-39-15, Showa-machi, Maebashi, Gunma, 371-8511, Japan. .
Kawabata-Iwakawa R; Division of Integrated Oncology Research, Initiative for Advanced Research, Gunma University, 3-39-15, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Suzuki T; Laboratory for Immunogenetics, RIKEN Center for Integrative Medical Sciences, 1-7-22, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
Suto T; Department of Anesthesiology, Gunma University Hospital, 3-39-15, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Takazawa T; Intensive Care Unit, Gunma University Hospital, 3-39-15, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Saito S; Department of Anesthesiology, Gunma University Hospital, 3-39-15, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 25; Vol. 12 (1), pp. 14520. Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Growth Differentiation Factor 15*/genetics
Neoplasms*
Anesthetics, Local/pharmacology ; Growth Differentiation Factor 9 ; HeLa Cells ; Humans ; Lidocaine/pharmacology ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure.
Autorzy:
Ceelen D; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Voors AA; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Tromp J; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
van Veldhuisen DJ; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Dickstein K; University of Bergen, Bergen, Norway.; Stavanger University Hospital, Stavanger, Norway.
de Boer RA; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Lang CC; School of Medicine Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School, Dundee, UK.
Anker SD; Department of Cardiology (CVK); and Berlin Institute of Health Center for Regenerative Therapies (BCRT); German Centre for Cardiovascular Research (DZHK) partner site Berlin; Charité Universitätsmedizin Berlin, Berlin, Germany.
Ng LL; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, and NIHR Leicester Biomedical Research Centre, Leicester, UK.
Metra M; Institute of Cardiology, ASST Spedali Civili di Brescia and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
Ponikowski P; Department of Heart Diseases, Wrocław Medical University, Wroclaw, Poland.; Center for Heart Diseases, University Hospital in Wrocław, Wroclaw, Poland.
Figarska SM; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
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Źródło:
European journal of heart failure [Eur J Heart Fail] 2022 Feb; Vol. 24 (2), pp. 308-320. Date of Electronic Publication: 2022 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Growth Differentiation Factor 15*/blood
Heart Failure*/physiopathology
Biomarkers ; Cohort Studies ; Humans ; Prognosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Letter: serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination-authors' reply.
Autorzy:
Myojin Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Hikita H; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Tahata Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Doi A; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Kato S; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Sasaki Y; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Shirai K; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Sakane S; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Yamada R; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Kodama T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Hagiwara H; Kansai Rosai Hospital, Amagasaki, Hyogo, Japan.
Imai Y; Ikeda Municipal Hospital, Osaka, Japan.
Hiramatsu N; Osaka Rosai Hospital, Osaka, Japan.
Tamura S; Minoh City Hospital, Osaka, Japan.
Yamamoto K; National Hospital Organization Minami Wakayama Medical Center, Wakayama, Japan.
Ohkawa K; Osaka International Cancer Institute, Osaka, Osaka, Japan.
Hijioka T; National Hospital Organization Osaka Minami Medical Center, Osaka, Japan.
Fukui H; Yao Municipal Hospital, Osaka, Japan.
Doi Y; Otemae Hospital, Osaka, Osaka, Japan.
Yamada Y; Kaizuka City Hospital, Osaka, Japan.
Yakushijin T; Osaka General Medical Center, Osaka, Osaka, Japan.
Mita E; National Hospital Organization Osaka National Hospital, Osaka, Japan.
Sakamori R; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Tatsumi T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
Takehara T; Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Apr; Vol. 55 (8), pp. 1061-1062.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Carcinoma, Hepatocellular*/diagnosis
Growth Differentiation Factor 15*/blood
Hepatitis C*/complications
Liver Neoplasms*/diagnosis
Hepacivirus ; Humans
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Letter: serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination.
Autorzy:
Chen L; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.
Tao X; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.
Zhao Y; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.
Zeng M; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.
Mi Y; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.; Department of Hepatology, Tianjin Second People's Hospital, Tianjin, China.; Tianjin Research Institute of Liver Diseases, Tianjin, China.
Xu L; Clinical School of the Second People's Hospital, Tianjin Medical University, Tianjin, China.; Department of Hepatology, Tianjin Second People's Hospital, Tianjin, China.
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Źródło:
Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Apr; Vol. 55 (8), pp. 1059-1060.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't; Comment
MeSH Terms:
Carcinoma, Hepatocellular*/diagnosis
Growth Differentiation Factor 15*/blood
Hepatitis C*/complications
Liver Neoplasms*/diagnosis
Hepacivirus ; Humans
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Camptothecin effectively treats obesity in mice through GDF15 induction.
Autorzy:
Lu JF; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Zhu MQ; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Xie BC; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Shi XC; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Liu H; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Zhang RX; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Xia B; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Wu JW; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
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Źródło:
PLoS biology [PLoS Biol] 2022 Feb 24; Vol. 20 (2), pp. e3001517. Date of Electronic Publication: 2022 Feb 24 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Camptothecin/*pharmacology
Glial Cell Line-Derived Neurotrophic Factor Receptors/*genetics
Growth Differentiation Factor 15/*genetics
Obesity/*prevention & control
Animals ; Body Weight/drug effects ; Body Weight/genetics ; Camptothecin/pharmacokinetics ; Cell Line ; Cell Line, Tumor ; Diet, High-Fat/adverse effects ; Eating/drug effects ; Eating/genetics ; Gene Expression Regulation/drug effects ; Glial Cell Line-Derived Neurotrophic Factor Receptors/metabolism ; Growth Differentiation Factor 15/metabolism ; HEK293 Cells ; HL-60 Cells ; Humans ; MCF-7 Cells ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Obese ; Obesity/etiology ; Obesity/genetics ; PC-3 Cells ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 593

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