Terbium-149 production: a focus on yield and quality improvement towards preclinical application.
Autorzy:
Favaretto C; Nuclear Medicine Department, University Hospital Basel, Basel, Switzerland.; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. GrundlerPV; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Talip Z; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Köster U; Institute Laue-Langevin, Grenoble, France.; Physics Department, ISOLDE/CERN, Geneva, Switzerland. Johnston K; Physics Department, ISOLDE/CERN, Geneva, Switzerland. Busslinger SD; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Sprung P; Department Hot Laboratory, Paul Scherrer Institute, Villigen-PSI, Switzerland. Hillhouse CC; Laboratory of Radiochemistry, Paul Scherrer Institute, Villigen-PSI, Switzerland. Eichler R; Laboratory of Radiochemistry, Paul Scherrer Institute, Villigen-PSI, Switzerland.; Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland. Schibli R; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland. Müller C; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland. van der Meulen NP; Center for Radiopharmaceutical Sciences ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. .; Laboratory of Radiochemistry, Paul Scherrer Institute, Villigen-PSI, Switzerland. .
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Scientific reports [Sci Rep] 2024 Feb 08; Vol. 14 (1), pp. 3284. Date of Electronic Publication: 2024 Feb 08.
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides.
Autorzy:
Beyer D; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Vaccarin C; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Deupi X; Condensed Matter Theory Group, Division of Scientific Computing, Theory, and Data, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Laboratory of Biomolecular Research, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland. Mapanao AK; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Cohrs S; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Sozzi-Guo F; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. GrundlerPV; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. van der Meulen NP; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Wang J; Institute of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Tanriver M; Institute of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Bode JW; Institute of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Schibli R; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Müller C; Center for Radiopharmaceutical Sciences, ETH-PSI, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. .; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. .
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EJNMMI research [EJNMMI Res] 2023 Apr 19; Vol. 13 (1), pp. 32. Date of Electronic Publication: 2023 Apr 19.
Activity Measurement of Sc and Calibration of Activity Measurement Instruments on Production Sites and Clinics.
Autorzy:
Juget F; Institute of Radiation Physics, 1007 Lausanne, Switzerland. Durán T; Institute of Radiation Physics, 1007 Lausanne, Switzerland. Nedjadi Y; Institute of Radiation Physics, 1007 Lausanne, Switzerland. Talip Z; Center of Radiopharmaceutical Sciences ETH_PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. GrundlerPV; Center of Radiopharmaceutical Sciences ETH_PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Favaretto C; Center of Radiopharmaceutical Sciences ETH_PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Casolaro P; Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, 3012 Bern, Switzerland. Dellepiane G; Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, 3012 Bern, Switzerland. Braccini S; Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, 3012 Bern, Switzerland. Bailat C; Institute of Radiation Physics, 1007 Lausanne, Switzerland. van der Meulen NP; Center of Radiopharmaceutical Sciences ETH_PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.
Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161.
Autorzy:
Juget F; Institute of Radiation Physics, Lausanne, Switzerland. . Talip Z; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland. Nedjadi Y; Institute of Radiation Physics, Lausanne, Switzerland. Durán MT; Institute of Radiation Physics, Lausanne, Switzerland. GrundlerPV; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland. Zeevaart JR; Radiochemistry, South African Nuclear Energy Corporation (Necsa), Brits, South Africa. van der Meulen NP; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, Villigen-PSI, Switzerland.; Laboratory of Radiochemistry, Paul Scherrer Institute, Villigen-PSI, Switzerland. Bailat C; Institute of Radiation Physics, Lausanne, Switzerland.
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EJNMMI physics [EJNMMI Phys] 2022 Mar 14; Vol. 9 (1), pp. 19. Date of Electronic Publication: 2022 Mar 14.
Combination of terbium-161 with somatostatin receptor antagonists-a potential paradigm shift for the treatment of neuroendocrine neoplasms.
Autorzy:
Borgna F; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Haller S; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Rodriguez JMM; Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, 8057, Zurich, Switzerland. Ginj M; The Joint Department of Medical Imaging, University Health Network, 200 Elizabeth St, Toronto, ON, M5G 2C4, Canada. GrundlerPV; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Zeevaart JR; South African Nuclear Energy Corporation (Necsa), Pelindaba, Brits, 0240, South Africa. Köster U; Institut Laue-Langevin, 38042, Grenoble, France. Schibli R; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. van der Meulen NP; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Müller C; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. .; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. .
Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging.
Autorzy:
Favaretto C; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Talip Z; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Borgna F; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. GrundlerPV; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Dellepiane G; Albert Einstein Center for Fundamental Physics (AEC), Laboratory of High Energy Physics (LHEP), University of Bern, 3012, Bern, Switzerland. Sommerhalder A; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Zhang H; Division Large Research Facilities, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. Schibli R; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093, Zurich, Switzerland. Braccini S; Albert Einstein Center for Fundamental Physics (AEC), Laboratory of High Energy Physics (LHEP), University of Bern, 3012, Bern, Switzerland. Müller C; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. van der Meulen NP; Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. .; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232, Villigen-PSI, Switzerland. .
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Źródło:
EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2021 Nov 14; Vol. 6 (1), pp. 37. Date of Electronic Publication: 2021 Nov 14.
Simultaneous Visualization of Lu-Labeled Somatostatin Analogues Using Dual-Isotope SPECT Imaging.
Autorzy:
Borgna F; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Barritt P; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. GrundlerPV; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Talip Z; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Cohrs S; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Zeevaart JR; Radiochemistry, South African Nuclear Energy Corporation (Necsa), Brits 0240, South Africa. Köster U; Institut Laue-Langevin, 38042 Grenoble, France. Schibli R; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland. van der Meulen NP; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Müller C; Center for Radiopharmaceutical Sciences, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.; Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland.
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Źródło:
Pharmaceutics [Pharmaceutics] 2021 Apr 12; Vol. 13 (4). Date of Electronic Publication: 2021 Apr 12.
Developments toward the Implementation of Sc Production at a Medical Cyclotron.
Autorzy:
van der Meulen NP; Laboratory of Radiochemistry, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland.; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Hasler R; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Talip Z; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. GrundlerPV; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Favaretto C; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Umbricht CA; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Müller C; Center of Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen-PSI, Switzerland. Dellepiane G; Albert Einstein Center for Fundamental Physics, Laboratory of High Energy Physics, University of Bern, 3012 Bern, Switzerland. Carzaniga TS; Albert Einstein Center for Fundamental Physics, Laboratory of High Energy Physics, University of Bern, 3012 Bern, Switzerland. Braccini S; Albert Einstein Center for Fundamental Physics, Laboratory of High Energy Physics, University of Bern, 3012 Bern, Switzerland.
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