Autor: "Gujral TS" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma.
Autorzy:: Ma RK; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Tsai PY; Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America.
Farghli AR; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Shumway A; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Kanke M; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Gordan JD; Division of Hematology/Oncology, Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, California, United States of America.
Gujral TS; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Vakili K; Department of Surgery, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Nukaya M; Department of Surgery, Division of Surgical Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Noetzli L; Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America.
Ronnekleiv-Kelly S; Department of Surgery, Division of Surgical Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Broom W; Alnylam Pharmaceuticals, Cambridge, Massachusetts, United States of America.
Barrow J; Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America.
Sethupathy P; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2024 Mar 21; Vol. 20 (3), pp. e1011216. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Adolescent ; Young Adult ; Humans ; HSP40 Heat-Shock Proteins/genetics ; HSP40 Heat-Shock Proteins/metabolism ; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits/genetics
SCR Disease Name:: Fibrolamellar hepatocellular carcinoma

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Skocz do pozycji: 2.

Tytuł:: Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation.
Autorzy:: Olson AT; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Kang Y; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Ladha AM; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.
Zhu S; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Lim CB; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Nabet B; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.
Lagunoff M; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.
Gujral TS; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America.
Geballe AP; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Microbiology, University of Washington, Seattle, Washington, United States of America.; Division of Clinical Research, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Medicine, University of Washington, Seattle, Washington, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2023 Sep 05; Vol. 19 (9), pp. e1011169. Date of Electronic Publication: 2023 Sep 05 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Herpesvirus 8, Human*/genetics
Sarcoma, Kaposi*
Humans ; Polypharmacology ; Africa ; Cognition ; Protein Serine-Threonine Kinases ; Intracellular Signaling Peptides and Proteins ; Receptor-Interacting Protein Serine-Threonine Kinases

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Skocz do pozycji: 3.

Tytuł:: Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors.
Autorzy:: Xue C; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Corey E; Department of Urology, University of Washington, Seattle, WA 98195, USA.
Gujral TS; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2022 Mar 29; Vol. 14 (7). Date of Electronic Publication: 2022 Mar 29.
Typ publikacji:: Journal Article

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Skocz do pozycji: 4.

Tytuł:: Machine learning identifies molecular regulators and therapeutics for targeting SARS-CoV2-induced cytokine release.
Autorzy:: Chan M; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Vijay S; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
McNevin J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Holland EC; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Gujral TS; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Pharmacology, University of Washington, Seattle, WA, USA.; Pokaż więcej
Źródło:: Molecular systems biology [Mol Syst Biol] 2021 Sep; Vol. 17 (9), pp. e10426.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiviral Agents/*pharmacology
Cytokines/*metabolism
Host-Pathogen Interactions/*physiology
Animals ; Azetidines/pharmacology ; Host-Pathogen Interactions/drug effects ; Humans ; Imidazoles/pharmacology ; Interleukin-1 Receptor-Associated Kinases/metabolism ; Janus Kinase 1/metabolism ; Lipopolysaccharides/toxicity ; Machine Learning ; Male ; Mice ; Mice, Inbred C57BL ; Neutrophils/virology ; Protein Kinase Inhibitors/pharmacology ; Purines/pharmacology ; Pyrazoles/pharmacology ; Pyridazines/pharmacology ; RAW 264.7 Cells ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/metabolism ; Sulfonamides/pharmacology

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Skocz do pozycji: 5.

Tytuł:: Profiling phospho-signaling networks in breast cancer using reverse-phase protein arrays.
Autorzy:: Gujral TS; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
Karp RL
Finski A
Chan M
Schwartz PE
MacBeath G
Sorger P; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2013 Jul 18; Vol. 32 (29), pp. 3470-6. Date of Electronic Publication: 2012 Sep 03.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Breast Neoplasms/*metabolism
Protein Array Analysis/*methods
Signal Transduction/*physiology
Cluster Analysis ; Female ; Humans ; Proteomics/methods ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-met/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism ; Axl Receptor Tyrosine Kinase

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Tytuł:: A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation.
Autorzy:: Gujral TS; Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.
MacBeath G; Pokaż więcej
Źródło:: PloS one [PLoS One] 2010 Apr 07; Vol. 5 (4), pp. e10024. Date of Electronic Publication: 2010 Apr 07.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Feedback, Physiological*
Gene Expression Regulation*
Signal Transduction*
Wnt Proteins/*metabolism
Alcohol Oxidoreductases/analysis ; Alcohol Oxidoreductases/genetics ; Cell Line ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; DNA-Binding Proteins/analysis ; DNA-Binding Proteins/genetics ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Transcription, Genetic ; Wnt3 Protein ; Wnt3A Protein

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Skocz do pozycji: 7.

Tytuł:: Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2.
Autorzy:: Gujral TS; Division of Cancer Biology and Genetics, Department of Pathology and Molecular Medicine, Cancer Research Institute, Botterell Hall Room 329, Queen's University, Kingston, ON, Canada K7L 3N6.
Mulligan LM; Pokaż więcej
Źródło:: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2006 Aug; Vol. 1073, pp. 234-40.
Typ publikacji:: Journal Article
MeSH Terms:: Mutation*
Adrenal Gland Neoplasms/*genetics
Multiple Endocrine Neoplasia Type 2a/*genetics
Pheochromocytoma/*genetics
Proto-Oncogene Proteins c-ret/*genetics
Humans ; Proto-Oncogene Mas

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