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    Tytuł:
    Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy.
    Autorzy:
    Byrareddy SN; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Arthos J; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
    Cicala C; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
    Villinger F; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. Division of Pathology, The Yerkes National Primate Center of Emory University, Atlanta, GA 30329, USA.
    Ortiz KT; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Little D; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Sidell N; Department of Obstetrics and Gynecology, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Kane MA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201, USA.
    Yu J; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201, USA.
    Jones JW; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201, USA.
    Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30680, USA.
    Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30680, USA.
    McKinnon LR; Centre for the AIDS Program of Research in South Africa (CAPRISA), Durban, South Africa.
    Arnold KB; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
    Woody CE; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.
    Walter L; Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
    Roos C; Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
    Noll A; Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
    Van Ryk D; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
    Jelicic K; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
    Cimbro R; Division of Rheumatology, Johns Hopkins School of Medicine, Baltimore, MD 21201, USA.
    Gumber S; Division of Pathology, The Yerkes National Primate Center of Emory University, Atlanta, GA 30329, USA.
    Reid MD; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Adsay V; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Amancha PK; Division of Pathology, The Yerkes National Primate Center of Emory University, Atlanta, GA 30329, USA.
    Mayne AE; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Parslow TG; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
    Fauci AS; Laboratory of Immunoregulation, NIAID, NIH, Bethesda, MD 20892, USA.
    Ansari AA; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. .
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    Źródło:
    Science (New York, N.Y.) [Science] 2016 Oct 14; Vol. 354 (6309), pp. 197-202.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antibodies, Monoclonal/*therapeutic use
    Antibodies, Monoclonal, Humanized/*therapeutic use
    Immunization, Passive/*methods
    Integrin alpha4/*immunology
    Integrin beta Chains/*immunology
    Simian Acquired Immunodeficiency Syndrome/*therapy
    Simian Acquired Immunodeficiency Syndrome/*virology
    Simian Immunodeficiency Virus/*immunology
    Viremia/*therapy
    Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal, Humanized/administration & dosage ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; Combined Modality Therapy ; Cytokines/blood ; Disease Models, Animal ; Female ; Gastrointestinal Tract/immunology ; Infusions, Intravenous ; Killer Cells, Natural/immunology ; Macaca mulatta ; Male ; Membrane Glycoproteins/immunology ; Simian Acquired Immunodeficiency Syndrome/blood ; Simian Acquired Immunodeficiency Syndrome/drug therapy ; Simian Immunodeficiency Virus/isolation & purification ; T-Lymphocyte Subsets/immunology ; Tretinoin/blood ; Viral Envelope Proteins/immunology ; Viral Load/immunology ; Viremia/blood ; Viremia/drug therapy ; Viremia/virology
    Czasopismo naukowe
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