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Wyszukujesz frazę ""HEK293 Cells"" wg kryterium: Temat


Tytuł:
A microfabricated lab-on-chip with three-dimensional electrodes for microscopic observation of bioelectromagnetic effects of cells.
Autorzy:
Lu Y; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: .
Shi Y; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China; Westlake Laboratory of Life Sciences and Biomedicine, Xihu District, Hangzhou 310024, Zhejiang Province, China; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China. Electronic address: .
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Źródło:
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2023 Dec; Vol. 154, pp. 108554. Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
HEK293 Cells*
Humans ; Cell Proliferation ; Cell Cycle ; Computer Simulation ; Electrodes
Czasopismo naukowe
Tytuł:
Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2.
Autorzy:
Roy AV; Functional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, QC, Canada.
Chan M; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Banadyga L; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.; National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, MB, Canada.
Chrétien M; Functional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, QC, Canada.
Mbikay M; Functional Endoproteolysis Laboratory, Montreal Clinical Research Institute, Montreal, QC, Canada. .
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Źródło:
Virology journal [Virol J] 2024 Jan 25; Vol. 21 (1), pp. 29. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Humans ; Chlorocebus aethiops ; SARS-CoV-2 ; Angiotensin-Converting Enzyme 2/genetics ; Quercetin/pharmacology ; Viral Proteins/metabolism ; Caco-2 Cells ; Spike Glycoprotein, Coronavirus/metabolism ; HEK293 Cells ; Giant Cells/pathology ; Protein Binding
Czasopismo naukowe
Tytuł:
Multidimensional exploration of the bitterness amelioration effect of roasting on Wuyi Rock tea.
Autorzy:
Su W; College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China; Institute of Food Science & Technology, Fuzhou University, Fuzhou, Fujian 350108, China.
Ni L; College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China; Institute of Food Science & Technology, Fuzhou University, Fuzhou, Fujian 350108, China. Electronic address: .
Chen Y; Institute of Food Science & Technology, Fuzhou University, Fuzhou, Fujian 350108, China.
Wang D; College of Chemical Engineering, Fuzhou University, Fuzhou, Fujian 350108, China; Institute of Food Science & Technology, Fuzhou University, Fuzhou, Fujian 350108, China.
Lin CC; Department of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu, Taiwan, Province of China, China.
Liu Y; Department of Food Science & Technology, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Liu Z; Institute of Food Science & Technology, Fuzhou University, Fuzhou, Fujian 350108, China. Electronic address: .
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Źródło:
Food chemistry [Food Chem] 2024 Mar 30; Vol. 437 (Pt 2), pp. 137954. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*
Alkaloids*
Humans ; HEK293 Cells ; Taste ; Tea/chemistry ; Receptors, Cell Surface
Czasopismo naukowe
Tytuł:
Decoding Molecular Mechanism Underlying Human Olfactory Receptor OR8D1 Activation by Sotolone Enantiomers.
Autorzy:
Wang J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Wang D; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Huang M; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Sun B; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Ren F; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Wu J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Zhang J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Li H; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Sun X; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology & Business University (BTBU), Beijing 100048, China.; Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Mar 13; Vol. 72 (10), pp. 5403-5415. Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Odorant*/chemistry
Humans ; HEK293 Cells ; Furans ; Smell ; Odorants/analysis
Czasopismo naukowe
Tytuł:
Exploring the cytotoxicity of dinuclear Ru(II)  p -cymene complexes appended N , N '-bis(4-substituted benzoyl)hydrazines: insights into the mechanism of apoptotic cell death.
Autorzy:
Abirami A; Centre for Organometallic Chemistry, School of Chemistry, Bharathidasan University, Tiruchirappalli - 620 024, India. .
Devan U; Molecular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, Bharathidasan University, Tiruchirappalli - 620 024, India.
Ramesh R; Centre for Organometallic Chemistry, School of Chemistry, Bharathidasan University, Tiruchirappalli - 620 024, India. .
Antony Joseph Velanganni A; Molecular Oncology Laboratory, Department of Biochemistry, School of Life Sciences, Bharathidasan University, Tiruchirappalli - 620 024, India.
Małecki JG; Department of Crystallography, Institute of Chemistry, University of Silesia, Katowice, Poland.
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Źródło:
Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2024 Mar 12; Vol. 53 (11), pp. 5167-5179. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Ruthenium*/pharmacology
Ruthenium*/chemistry
Coordination Complexes*/pharmacology
Coordination Complexes*/metabolism
Antineoplastic Agents*/chemistry
Cymenes*
Humans ; Reactive Oxygen Species/metabolism ; HEK293 Cells ; Spectroscopy, Fourier Transform Infrared ; Apoptosis ; Hydrazines/pharmacology ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Synthesis, characterization, and cancer cell-selective cytotoxicity of mixed-ligand cobalt(III) complexes of 8-hydroxyquinolines and phenanthroline bases.
Autorzy:
Deka B; Department of Chemistry, Handique Girls' College, Guwahati 781001, Assam, India. .
Sarkar T; Department of Chemistry, Handique Girls' College, Guwahati 781001, Assam, India. .
Bhattacharyya A; Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India. .
Butcher RJ; Department of Chemistry, Howard University, 525 College Street, NW 20059, USA. .
Banerjee S; Department of Chemistry, Indian Institute of Technology (BHU), Varanasi, UP 221005, India. .
Deka S; Department of Chemistry, University of Delhi, New Delhi 110024, India. .
Saikia KK; Department of Bioengineering and Technology, GUIST, Gauhati University, Guwahati 781014, Assam, India. .
Hussain A; Department of Chemistry, Handique Girls' College, Guwahati 781001, Assam, India. .
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Źródło:
Dalton transactions (Cambridge, England : 2003) [Dalton Trans] 2024 Mar 12; Vol. 53 (11), pp. 4952-4961. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Coordination Complexes*/chemistry
Neoplasms*
Humans ; Phenanthrolines/chemistry ; Oxyquinoline/pharmacology ; Ligands ; Cobalt ; HEK293 Cells ; Copper/chemistry
Czasopismo naukowe
Tytuł:
Real-time resolution studies of the regulation of lactate production by hexokinases binding to mitochondria in single cells.
Autorzy:
John S; Department of Medicine (Division of Cardiology), David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.
Calmettes G; Department of Medicine (Division of Cardiology), David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.
Xu S; California NanoSystems Institute (CNSI) 2151, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.
Ribalet B; Department of Physiology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 08; Vol. 19 (3), pp. e0300150. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Hexokinase*/genetics
Hexokinase*/metabolism
Lactic Acid*/metabolism
Humans ; HEK293 Cells ; Mitochondria/metabolism ; Pyruvates/metabolism
Czasopismo naukowe
Tytuł:
Preparation and recognition mechanism study of an scFv targeting chloramphenicol for a hybridization chain reaction-CRISPR/Cas12a amplified fluoroimmunoassay.
Autorzy:
Zhang F; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Hao D; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Liu R; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Wang J; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Sang Y; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Wang S; Medical College, Nankai University, Tianjin, 300500, China. Electronic address: .
Wang X; College of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China. Electronic address: .
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Źródło:
Analytica chimica acta [Anal Chim Acta] 2024 Mar 08; Vol. 1293, pp. 342283. Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Chloramphenicol*
Biosensing Techniques*
Humans ; CRISPR-Cas Systems ; HEK293 Cells ; Nucleic Acid Hybridization ; Fluoroimmunoassay ; Antibodies
Czasopismo naukowe
Tytuł:
Aspergillus fumigatus secretes a protease(s) that displays in silico binding affinity towards the SARS-CoV-2 spike protein and mediates SARS-CoV-2 pseudovirion entry into HEK-293T cells.
Autorzy:
Mjokane N; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Akintemi EO; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Sabiu S; Department of Biotechnology and Food Science, Faculty of Applied Science, Durban University of Technology, 4000, Durban, P.O. Box 1334, South Africa.
Gcilitshana OMN; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Albertyn J; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Pohl CH; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa.
Sebolai OM; Department of Microbiology and Biochemistry, University of the Free State, 205 Nelson Mandela Drive, Park West, 9301, Bloemfontein, South Africa. .
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Źródło:
Virology journal [Virol J] 2024 Mar 06; Vol. 21 (1), pp. 58. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Peptide Hydrolases*
COVID-19*
Humans ; Spike Glycoprotein, Coronavirus ; Aspergillus fumigatus ; SARS-CoV-2 ; HEK293 Cells ; Molecular Docking Simulation ; Peptides
Czasopismo naukowe
Tytuł:
Petrol Note in Riesling - 1,1,6-Trimethyl-1,2-dihydronaphthalene (TDN) Selectively Activates Human Odorant Receptor OR8H1.
Autorzy:
Haag F; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.
Frey T; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.; TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
Ball L; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.; TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
Hoffmann S; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.
Krautwurst D; Leibniz-Institute for Food Systems Biology at the Technical University of Munich, 85354 Freising, Germany.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Mar 06; Vol. 72 (9), pp. 4888-4896. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Wine*/analysis
Receptors, Odorant*/genetics
Vitis*/chemistry
Naphthalenes*
Humans ; HEK293 Cells ; Australia ; Odorants/analysis ; Fruit/chemistry
Czasopismo naukowe
Tytuł:
Chiral Nanoclusters as Alternative Therapeutic Strategies to Confront the Health Threat from Antibiotic-Resistant Pathogens.
Autorzy:
Wang Z; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Tian Y; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Hao J; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Liu Y; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Tang J; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Xu Z; State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Liu Y; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Tang B; School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Huang X; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610065, China.
Zhu N; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Li Z; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Hu L; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Li L; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Wang Y; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Jiang G; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
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Źródło:
ACS nano [ACS Nano] 2024 Mar 05; Vol. 18 (9), pp. 7253-7266. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Metal Nanoparticles*/therapeutic use
Anti-Infective Agents*
Animals ; Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Silver/pharmacology ; Silver/therapeutic use ; HEK293 Cells ; Pseudomonas aeruginosa ; Microbial Sensitivity Tests ; Mammals
Czasopismo naukowe
Tytuł:
Development and application of an indirect ELISA for detection of antibodies against emerging atypical porcine pestivirus.
Autorzy:
Song H; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Gao X; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Li J; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Dong X; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Fu Y; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Shao L; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Zhang J; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China.
Qiu HJ; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China. .
Luo Y; State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 678 Haping Road, Harbin, 150069, China. .
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Źródło:
Virology journal [Virol J] 2024 Mar 04; Vol. 21 (1), pp. 53. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:
Journal Article
MeSH Terms:
Asymptomatic Infections*
Pestivirus*
Humans ; Adult ; Animals ; Swine ; HEK293 Cells ; Seroepidemiologic Studies ; Enzyme-Linked Immunosorbent Assay
Czasopismo naukowe
Tytuł:
Real-Time Determination of Intracellular cAMP Reveals Functional Coupling of G s Protein to the Melatonin MT 1 Receptor.
Autorzy:
Tse LH; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Cheung ST; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Lee S; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Wong YH; Division of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.; State Key Laboratory of Molecular Neuroscience, Molecular Neuroscience Center, Hong Kong University of Science and Technology, Hong Kong, China.; Hong Kong Center for Neurodegenerative Diseases, 17 Science Park West Avenue, Hong Kong Science Park, Shatin, Hong Kong, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 02; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Melatonin*/pharmacology
Humans ; Receptors, Melatonin/metabolism ; HEK293 Cells ; Receptor, Melatonin, MT1/metabolism ; Receptor, Melatonin, MT2/metabolism ; GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
Enhancing the production of adeno-associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design-of-experiment optimization of triple plasmid ratio.
Autorzy:
Park S; Department of Biological Sciences, KAIST, Daejeon, Republic of Korea.
Shin S; Department of Biological Sciences, KAIST, Daejeon, Republic of Korea.
Lee H; Department of Chemistry, KAIST, Daejeon, Republic of Korea.
Jang JH; Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Republic of Korea.; R&D Center, GluGene Therapeutics Inc., Seoul, Republic of Korea.
Lee GM; Department of Biological Sciences, KAIST, Daejeon, Republic of Korea.
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Źródło:
Biotechnology journal [Biotechnol J] 2024 Mar; Vol. 19 (3), pp. e2300667.
Typ publikacji:
Journal Article
MeSH Terms:
Capsid*
Parvovirinae*/genetics
Humans ; HEK293 Cells ; Genetic Vectors/genetics ; Dependovirus/genetics ; Plasmids/genetics ; Capsid Proteins/genetics
SCR Organism:
Adeno-associated virus-2
Czasopismo naukowe
Tytuł:
Clinical and Molecular Characterization of Nine Novel Antithrombin Mutations.
Autorzy:
Kállai J; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; HUN-REN-UD Cell Biology and Signaling Research Group, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gindele R; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Pénzes-Daku K; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Balogh G; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Bogáti R; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Bécsi B; Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Katona É; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Oláh Z; Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Ilonczai P; Jósa András Teaching Hospital of University of Debrecen, 4400 Nyíregyháza, Hungary.
Boda Z; Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Róna-Tas Á; Department Medical Center of the Hungarian Defence Forces, National Hemophilia Center and Hemostasis, 1134 Budapest, Hungary.
Nemes L; Department Medical Center of the Hungarian Defence Forces, National Hemophilia Center and Hemostasis, 1134 Budapest, Hungary.
Marton I; Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.; Department of Transfusion Medicine, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Bereczky Z; Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antithrombins*/chemistry
Antithrombin III Deficiency*/genetics
Humans ; HEK293 Cells ; Anticoagulants ; Heparin/metabolism ; Mutation
Czasopismo naukowe
Tytuł:
Design, synthesis, and biological evaluation of novel quinoxaline aryl ethers as anticancer agents.
Autorzy:
Nakka S; Department of Chemistry, School of Applied Sciences and Humanities, Vignan's Foundation for Science Technology and Research University (VFSTR), Guntur, Andhra Pradesh, India.
Raza A; Department of Pharmacology, Penn State Cancer Institute, Penn State College of Medicine, 500 University Drive, Hershey, Pennsylvania, USA.
Chaitanya KS; Department of Chemistry, Birla Institute of Technology and Science, Hyderabad Campus, Hyderabad, Telangana, India.
Bandaru NVMR; Department of Chemistry, Birla Institute of Technology and Science, Hyderabad Campus, Hyderabad, Telangana, India.
Chandu A; Department of Pharmacy, Medicinal Chemistry Research Laboratory, Birla Institute of Technology and Science Pilani, Pilani Campus, Pilani, Rajasthan, India.
Murugesan S; Department of Pharmacy, Medicinal Chemistry Research Laboratory, Birla Institute of Technology and Science Pilani, Pilani Campus, Pilani, Rajasthan, India.
Devunuri N; Department of Chemistry, School of Applied Sciences and Humanities, Vignan's Foundation for Science Technology and Research University (VFSTR), Guntur, Andhra Pradesh, India.
Sharma AK; Department of Pharmacology, Penn State Cancer Institute, Penn State College of Medicine, 500 University Drive, Hershey, Pennsylvania, USA.
Chandrasekhar KVG; Department of Chemistry, Birla Institute of Technology and Science, Hyderabad Campus, Hyderabad, Telangana, India.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2024 Mar; Vol. 103 (3), pp. e14502.
Typ publikacji:
Journal Article
MeSH Terms:
Ethers*
Antineoplastic Agents*/chemistry
Humans ; Cell Line, Tumor ; Molecular Docking Simulation ; Quinoxalines/pharmacology ; HEK293 Cells ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Apoptosis ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Identification and genetic characterization of a recently identified enterovirus C116 in China.
Autorzy:
Han ZZ; Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, China.; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Li JC; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiao JB; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Hong M; Tibet Center for Disease Control and Prevention, Lhasa City, Tibet Autonomous Region, China.
Lu HH; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Song Y; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Liu Y; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Wang R; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Fu HH; Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, China.
Wang FM; Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, China.
Zhu SL; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yan DM; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Ji TJ; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhao LQ; Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, China.
Zhang Y; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.; WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
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Źródło:
Journal of medical virology [J Med Virol] 2024 Mar; Vol. 96 (3), pp. e29503.
Typ publikacji:
Journal Article
MeSH Terms:
Enterovirus*/genetics
Enterovirus Infections*/epidemiology
Child ; Humans ; China/epidemiology ; Antigens, Viral ; HEK293 Cells
Czasopismo naukowe
Tytuł:
SPINK5 inhibits esophageal squamous cell carcinoma metastasis via immune activity.
Autorzy:
Chen J; Department of Oncology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Lu J; The Health Supervision Institute of Suzhou, Suzhou, Jiangsu, China.
Chen Z; Department of Nuclear Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Liu Z; Department of Oncology, Suqian Hospital Affiliated to Xuzhou Medical University, Suqian Hospital of Nanjing Drum Tower Hospital Group, Suqian, Jiangsu, China.
Sun Y; Department of Pathology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
He S; Department of Oncology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Mi Y; Department of Cardio-Thoracic Surgery, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Gao Y; Department of Gastroenterology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Shen D; Department of Oncology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
Lin Q; Department of Oncology, Jiangyin People's Hospital, Jiangyin Clinical College of Xuzhou Medical University, Jiangyin Hospital Affiliated to Nantong University, Jiangyin, Jiangsu, China.
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Źródło:
The journal of gene medicine [J Gene Med] 2024 Mar; Vol. 26 (3), pp. e3667.
Typ publikacji:
Journal Article
MeSH Terms:
Esophageal Neoplasms*/immunology
Esophageal Neoplasms*/metabolism
Esophageal Squamous Cell Carcinoma*/immunology
Esophageal Squamous Cell Carcinoma*/metabolism
Serine Peptidase Inhibitor Kazal-Type 5*/metabolism
Humans ; HEK293 Cells ; Lipopolysaccharides ; NF-kappa B/metabolism ; RNA, Messenger/metabolism ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł:
Touch sensation requires the mechanically gated ion channel ELKIN1.
Autorzy:
Chakrabarti S; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Klich JD; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Khallaf MA; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.; Department of Zoology and Entomology, Faculty of Science, Assiut University, Assiut 71516, Egypt.
Hulme AJ; School of Medical, Indigenous and Health Sciences, Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.
Sánchez-Carranza O; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Baran ZM; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.; Molecular and Cellular Basis of Behavior, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Rossi A; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Huang AT; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Pohl T; Molecular and Cellular Basis of Behavior, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Fleischer R; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Fürst C; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.; Molecular Pathways in Cortical Development, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Hammes A; Molecular Pathways in Cortical Development, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Bégay V; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.
Hörnberg H; Molecular and Cellular Basis of Behavior, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.; NeuroCure Cluster of Excellence, Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
Finol-Urdaneta RK; School of Medical, Indigenous and Health Sciences, Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.
Poole K; School of Biomedical Sciences, Faculty of Medicine & Health, University of New South Wales, Sydney, NSW 2052, Australia.
Dottori M; School of Medical, Indigenous and Health Sciences, Molecular Horizons, University of Wollongong, Wollongong, NSW 2522, Australia.
Lewin GR; Molecular Physiology of Somatic Sensation Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin-Buch, Germany.; Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; German Center for Mental Health (DZPG), partner site Berlin, 10117 Berlin, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar; Vol. 383 (6686), pp. 992-998. Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:
Journal Article
MeSH Terms:
Ion Channels*/genetics
Ion Channels*/physiology
Mechanoreceptors*/physiology
Mechanotransduction, Cellular*/genetics
Mechanotransduction, Cellular*/physiology
Membrane Proteins*/genetics
Membrane Proteins*/physiology
Sensory Receptor Cells*
Touch Perception*
Animals ; Humans ; Mice ; HEK293 Cells ; RNA, Small Interfering ; Touch ; Mice, Mutant Strains ; Male ; Female
Czasopismo naukowe
Tytuł:
The expression system influences stability, maturation efficiency, and oligomeric properties of the potassium-chloride co-transporter KCC2.
Autorzy:
Kok M; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Hartnett-Scott K; Department of Neurobiology and the Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Happe CL; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
MacDonald ML; Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Aizenman E; Department of Neurobiology and the Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: .
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Źródło:
Neurochemistry international [Neurochem Int] 2024 Mar; Vol. 174, pp. 105695. Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
K Cl- Cotransporters*/metabolism
Animals ; Humans ; Rats ; Endoplasmic Reticulum-Associated Degradation ; HEK293 Cells ; Potassium Chloride/metabolism ; Saccharomyces cerevisiae/metabolism ; Symporters/genetics ; Symporters/metabolism
Czasopismo naukowe

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