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Tytuł :
The switch from Gd-DTPA to Gd-DOTA is not associated with decrease of the T1 signal intensity of the pallidus and dentate in a pediatric population.
Autorzy :
Gulino P; Radiology Unit, Meyer Children's Hospital, Florence, Italy.; Radiology Unit, Ospedale Maggiore 'Carlo Alberto Pizzardi,' AUSL, Bologna, Italy.
Bianchi A; Neuroradiology Unit, Careggi University Hospital, Florence, Italy.
Diciotti S; Department of Electrical, Electronic, and Information Engineering 'Guglielmo Marconi,' University of Bologna, Cesena, Italy.
Scionti A; Radiology Unit, University of Pisa, Pisa, Italy.
Sali L; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Italy.
Papadopulos P; Radiology Unit, Meyer Children's Hospital, Florence, Italy.
Mascalchi M; Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Italy.; Neuroradiology Research Program, Meyer Children Hospital, Florence, Italy.
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Źródło :
Acta radiologica (Stockholm, Sweden : 1987) [Acta Radiol] 2021 Mar; Vol. 62 (3), pp. 368-376. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Contrast Media*
Gadolinium DTPA*
Heterocyclic Compounds*
Magnetic Resonance Imaging*
Organometallic Compounds*
Dentate Gyrus/*diagnostic imaging
Globus Pallidus/*diagnostic imaging
Adolescent ; Brain Neoplasms/diagnostic imaging ; Child ; Female ; Humans ; Male ; Middle Cerebellar Peduncle/diagnostic imaging ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Short-cycle therapy (5 days on/2 days off) with a lamivudine + dolutegravir regimen in a cohort of virologically suppressed patients with HIV infection.
Autorzy :
Lanzafame M; Unità Semplice Organizzativa 'Diagnosi e Terapia dell'infezione da HIV', Ospedale Policlinico 'G.B. Rossi',Verona, Italy. Electronic address: .
Lattuada E; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Gottardo R; Unità Complessa di Medicina Legale, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Piacentini D; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Be G; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Razzaboni E; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Cattaneo P; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Luise D; Unità Complessa di Malattie Infettive, Ospedale Policlinico 'G.B. Rossi',Verona, Italy.
Vento S; Faculty of Medicine, University of Puthisastra, Phnom Penh, Cambodia.
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Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2021 Mar; Vol. 57 (3), pp. 106290. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Letter; Observational Study
MeSH Terms :
Anti-HIV Agents/*therapeutic use
Antiretroviral Therapy, Highly Active/*methods
HIV Infections/*drug therapy
Heterocyclic Compounds, 3-Ring/*therapeutic use
Lamivudine/*therapeutic use
Oxazines/*therapeutic use
Piperazines/*therapeutic use
Pyridones/*therapeutic use
Reverse Transcriptase Inhibitors/*therapeutic use
Adult ; Aged ; Anti-HIV Agents/adverse effects ; Antiretroviral Therapy, Highly Active/adverse effects ; Cohort Studies ; Drug Therapy, Combination ; Female ; Heterocyclic Compounds, 3-Ring/adverse effects ; Humans ; Lamivudine/adverse effects ; Male ; Middle Aged ; Oxazines/adverse effects ; Piperazines/adverse effects ; Pyridones/adverse effects ; Reverse Transcriptase Inhibitors/adverse effects
Raport
Tytuł :
Effect of Freeze-Thaw Cycles on the Oxidation of Protein and Fat and Its Relationship with the Formation of Heterocyclic Aromatic Amines and Advanced Glycation End Products in Raw Meat.
Autorzy :
Wu X; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Zhang Z; State Key Laboratory of Food Safety Technology for Meat Products, Yinxiang Group, Xianmen 361100, China.
He Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Wang Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Qin F; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Zeng M; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
Chen J; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 26; Vol. 26 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Adipose Tissue/*metabolism
Amines/*metabolism
Heterocyclic Compounds/*metabolism
Proteins/*metabolism
Amines/chemistry ; Animals ; Chickens ; Cooking ; Freezing/adverse effects ; Heterocyclic Compounds/chemistry ; Humans ; Maillard Reaction ; Meat/analysis ; Oxidation-Reduction ; Pork Meat/analysis ; Swine ; Thiobarbituric Acid Reactive Substances/chemistry ; Thiobarbituric Acid Reactive Substances/metabolism
Czasopismo naukowe
Tytuł :
Demonstration of Green Solvent Performance on O,S,N-Heterocycles Synthesis: Metal-Free Click Chemistry and Buchwald-Hartwig Coupling.
Autorzy :
Campos JF; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France.
Cailler M; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France.
Claudel R; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France.
Prot B; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France.
Besson T; Normandie Univ., UNIROUEN, INSA Rouen, CNRS, COBRA UMR 6014, 76000 Rouen, France.
Berteina-Raboin S; Institut de Chimie Organique et Analytique (ICOA), Université d'Orléans UMR-CNRS 7311, BP 6759, Rue de Chartres, 45067 Orléans CEDEX 2, France.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 18; Vol. 26 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Green Chemistry Technology*
Click Chemistry/*methods
Heterocyclic Compounds/*chemical synthesis
Metals/*chemistry
Solvents/*chemistry
Heterocyclic Compounds/chemistry
Czasopismo naukowe
Tytuł :
Unveiling the basis of antiretroviral therapy-induced osteopenia: the effects of Dolutegravir, Darunavir and Atazanavir on osteogenesis.
Autorzy :
Cazzaniga A; General Pathology.
Scrimieri R; General Pathology.
Galli M; Infectious Diseases Unit, Department of Biomedical and Clinical Sciences 'Luigi Sacco', Università degli Studi di Milano, Milan, Italy.
Maier J; General Pathology.
Rusconi S; Infectious Diseases Unit, Department of Biomedical and Clinical Sciences 'Luigi Sacco', Università degli Studi di Milano, Milan, Italy.
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Źródło :
AIDS (London, England) [AIDS] 2021 Feb 02; Vol. 35 (2), pp. 213-218.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-HIV Agents*/adverse effects
Bone Diseases, Metabolic*/chemically induced
HIV Infections*/complications
HIV Infections*/drug therapy
Atazanavir Sulfate/*adverse effects
Darunavir/*adverse effects
Heterocyclic Compounds, 3-Ring/*adverse effects
Oxazines/*adverse effects
Piperazines/*adverse effects
Pyridones/*adverse effects
Atazanavir Sulfate/therapeutic use ; Darunavir/therapeutic use ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Humans ; Osteogenesis ; Oxazines/therapeutic use ; Piperazines/therapeutic use ; Pyridones/therapeutic use
Czasopismo naukowe
Tytuł :
Exogenous Strigolactones alleviate KCl stress by regulating photosynthesis, ROS migration and ion transport in Malus hupehensis Rehd.
Autorzy :
Zheng X; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China.
Li Y; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China.
Xi X; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China.
Ma C; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China.
Sun Z; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China; College of Life Science, Qingdao Agricultural University, Qingdao 266109, China.
Yang X; College of Plant Protection, Shenyang Agricultural University, Shenyang 110866, China.
Li X; State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
Tian Y; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China.
Wang C; College of Horticulture, Qingdao Agricultural University, Qingdao 266109, China; Qingdao Key Laboratory of Genetic Improvement and Breeding in Horticulture Plants, Qingdao 266109, China. Electronic address: .
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Feb; Vol. 159, pp. 113-122. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds, 3-Ring*/pharmacology
Ion Transport*/drug effects
Lactones*/pharmacology
Malus*/drug effects
Photosynthesis*/drug effects
Reactive Oxygen Species*/metabolism
Stress, Physiological*/drug effects
Gene Expression Regulation, Plant/drug effects ; Genes, Plant/genetics ; Seedlings/drug effects
Czasopismo naukowe
Tytuł :
A novel magnetic solid-phase extraction method for detection of 14 heterocyclic aromatic amines by UPLC-MS/MS in meat products.
Autorzy :
Shan S; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Ma Y; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Sun C; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Guo X; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Zheng H; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.
Xu X; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, China. Electronic address: .
Qin L; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, China.
Hu J; School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China; Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Feb 01; Vol. 337, pp. 127630. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds/*analysis
Meat Products/*analysis
Nanoparticles/*chemistry
Solid Phase Extraction/*methods
Amines/analysis ; Amines/chemistry ; Amines/isolation & purification ; Animals ; Carbolines/analysis ; Chromatography, Liquid ; Food Analysis/methods ; Heterocyclic Compounds/isolation & purification ; Imidazoles/analysis ; Indoles/chemistry ; Magnetic Phenomena ; Microscopy, Electron, Scanning ; Polymers/chemistry ; Pork Meat/analysis ; Quinolines/analysis ; Quinoxalines/analysis ; Solid Phase Extraction/instrumentation ; Spectroscopy, Fourier Transform Infrared ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion.
Autorzy :
Giannangelo C; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Siddiqui G; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
De Paoli A; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Anderson BM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.
Edgington-Mitchell LE; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.; Department of Maxillofacial Surgery, College of Dentistry, New York University, New York, New York, United States of America.
Charman SA; Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Creek DJ; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Jun 26; Vol. 16 (6), pp. e1008485. Date of Electronic Publication: 2020 Jun 26 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Erythrocytes*/metabolism
Erythrocytes*/parasitology
Adamantane/*analogs & derivatives
Antimalarials/*pharmacology
Hemoglobins/*metabolism
Heterocyclic Compounds, 1-Ring/*pharmacology
Peroxides/*pharmacology
Plasmodium falciparum/*metabolism
Spiro Compounds/*pharmacology
Adamantane/pharmacology ; Hemoglobins/genetics ; Heterocyclic Compounds/chemistry ; Heterocyclic Compounds/pharmacology ; Humans ; Plasmodium falciparum/genetics ; Proteomics
Czasopismo naukowe
Tytuł :
A review of the pharmacology and clinical profile of lumateperone for the treatment of schizophrenia.
Autorzy :
Snyder GL; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States. Electronic address: .
Vanover KE; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States.
Davis RE; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States.
Li P; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States.
Fienberg A; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States.
Mates S; Intra-Cellular Therapies, Inc., The Alexandria Center for Life Science, New York, NY, United States.
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Źródło :
Advances in pharmacology (San Diego, Calif.) [Adv Pharmacol] 2021; Vol. 90, pp. 253-276. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heterocyclic Compounds, 4 or More Rings/*therapeutic use
Schizophrenia/*drug therapy
Animals ; Antipsychotic Agents/therapeutic use ; Behavior ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Heterocyclic Compounds, 4 or More Rings/chemistry ; Humans ; Schizophrenia/diagnostic imaging ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Lumateperone: A Novel Antipsychotic for Schizophrenia.
Autorzy :
Greenwood J; Nova Southeastern University, Fort Lauderdale, FL, USA.
Acharya RB; Nova Southeastern University, Fort Lauderdale, FL, USA.
Marcellus V; Nova Southeastern University, Fort Lauderdale, FL, USA.
Rey JA; Nova Southeastern University, Fort Lauderdale, FL, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Jan; Vol. 55 (1), pp. 98-104. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antipsychotic Agents/*therapeutic use
Heterocyclic Compounds, 4 or More Rings/*therapeutic use
Schizophrenia/*drug therapy
Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/adverse effects ; Antipsychotic Agents/pharmacokinetics ; Heterocyclic Compounds, 4 or More Rings/administration & dosage ; Heterocyclic Compounds, 4 or More Rings/adverse effects ; Heterocyclic Compounds, 4 or More Rings/pharmacokinetics ; Humans ; Randomized Controlled Trials as Topic ; Treatment Outcome ; United States ; United States Food and Drug Administration
Czasopismo naukowe
Tytuł :
Dolutegravir and pregnancy outcomes in women on antiretroviral therapy in Brazil: a retrospective national cohort study.
Autorzy :
Pereira GFM; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Kim A; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Jalil EM; Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.
Fernandes Fonseca F; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: .
Shepherd BE; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Veloso VG; Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.
Rick F; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Ribeiro R; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Pimenta MC; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Beber A; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Corrêa RG; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Lima R; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil.
Maruri F; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
McGowan CC; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Schwartz Benzaken A; Department of Surveillance, Prevention, and Control of STIs, AIDS, and Viral Hepatitis, Ministry of Health, Brasília, Brazil; AIDS Health Care Foundation, Global Program, São Paulo, Brazil.
Grinsztejn B; Fiocruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, Brazil.
Castilho JL; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
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Corporate Authors :
National Cohort Study of Dolutegravir and Pregnancy Outcomes in Brazil
Źródło :
The lancet. HIV [Lancet HIV] 2021 Jan; Vol. 8 (1), pp. e33-e41.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
HIV Infections/*complications
HIV Integrase Inhibitors/*adverse effects
Heterocyclic Compounds, 3-Ring/*adverse effects
Neural Tube Defects/*etiology
Oxazines/*adverse effects
Piperazines/*adverse effects
Pyridones/*adverse effects
Abortion, Spontaneous/epidemiology ; Abortion, Spontaneous/etiology ; Adult ; Antiretroviral Therapy, Highly Active/adverse effects ; Brazil/epidemiology ; Comorbidity ; Female ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV Infections/virology ; HIV Integrase Inhibitors/administration & dosage ; HIV Integrase Inhibitors/therapeutic use ; Heterocyclic Compounds, 3-Ring/administration & dosage ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Humans ; Neural Tube Defects/diagnosis ; Neural Tube Defects/epidemiology ; Oxazines/administration & dosage ; Oxazines/therapeutic use ; Piperazines/administration & dosage ; Piperazines/therapeutic use ; Pregnancy ; Pregnancy Outcome ; Pyridones/administration & dosage ; Pyridones/therapeutic use ; Retrospective Studies ; Stillbirth ; Young Adult
Czasopismo naukowe
Tytuł :
A laboratory study on dissipation and risk assessment of the proinsecticide thiocyclam and its metabolite nereistoxin in tomato using liquid chromatography high resolution mass spectrometry.
Autorzy :
López-Ruiz R; Research Group 'Analytical Chemistry of Contaminants', Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain.
Belmonte-Sánchez E; Research Group 'Analytical Chemistry of Contaminants', Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain.
Romero-González R; Research Group 'Analytical Chemistry of Contaminants', Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain.
Martínez Vidal JL; Research Group 'Analytical Chemistry of Contaminants', Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain.
Ramírez-Cassinello JJ; Laboratorio Analítico Bioclínico, S.L. Research Department, Almería E-04131, Spain.
Garrido Frenich A; Research Group 'Analytical Chemistry of Contaminants', Department of Chemistry and Physics, Research Centre for Mediterranean Intensive Agrosystems and Agri-Food Biotechnology (CIAIMBITAL), University of Almeria, Agrifood Campus of International Excellence, ceiA3, E-04120 Almeria, Spain. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 May 15; Vol. 344, pp. 128729. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, High Pressure Liquid*
Laboratories*
Mass Spectrometry*
Heterocyclic Compounds, 1-Ring/*analysis
Lycopersicon esculentum/*chemistry
Pesticides/*analysis
Fruit/chemistry ; Heterocyclic Compounds, 1-Ring/metabolism ; Lycopersicon esculentum/metabolism ; Marine Toxins/analysis ; Marine Toxins/metabolism ; Pesticides/metabolism ; Risk Assessment
Czasopismo naukowe
Tytuł :
Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study.
Autorzy :
Hauser A; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Kusejko K; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Johnson LF; Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa.
Günthard HF; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Riou J; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Wandeler G; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.; Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.
Egger M; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.; Centre for Infectious Disease Epidemiology and Research, University of Cape Town, South Africa.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Kouyos RD; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
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Źródło :
PLoS medicine [PLoS Med] 2020 Dec 14; Vol. 17 (12), pp. e1003397. Date of Electronic Publication: 2020 Dec 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Viral*
Models, Theoretical*
HIV Infections/*drug therapy
HIV Integrase Inhibitors/*therapeutic use
HIV-1/*drug effects
Heterocyclic Compounds, 3-Ring/*therapeutic use
Oxazines/*therapeutic use
Piperazines/*therapeutic use
Pyridones/*therapeutic use
Drug Substitution ; Female ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/virology ; HIV Integrase Inhibitors/adverse effects ; HIV Integrase Inhibitors/supply & distribution ; HIV-1/pathogenicity ; Heterocyclic Compounds, 3-Ring/adverse effects ; Heterocyclic Compounds, 3-Ring/supply & distribution ; Humans ; Male ; Oxazines/adverse effects ; Oxazines/supply & distribution ; Piperazines/adverse effects ; Piperazines/supply & distribution ; Pyridones/adverse effects ; Pyridones/supply & distribution ; South Africa/epidemiology ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Stabilization Strategies for Linear Minigastrin Analogues: Further Improvements via the Inclusion of Proline into the Peptide Sequence.
Autorzy :
Klingler M; Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Hörmann AA; Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Rangger C; Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
Desrues L; INSERM U1239, DC2N, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76000 Rouen, France.
Castel H; INSERM U1239, DC2N, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76000 Rouen, France.
Gandolfo P; INSERM U1239, DC2N, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen Normandy, 76000 Rouen, France.
von Guggenberg E; Department of Nuclear Medicine, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Dec 10; Vol. 63 (23), pp. 14668-14679. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrins/*metabolism
Heterocyclic Compounds, 1-Ring/*metabolism
Proline/*chemistry
Radiopharmaceuticals/*metabolism
Amino Acid Sequence ; Animals ; Cell Line, Tumor ; Drug Stability ; Female ; Gastrins/chemical synthesis ; Gastrins/pharmacokinetics ; Heterocyclic Compounds, 1-Ring/chemical synthesis ; Heterocyclic Compounds, 1-Ring/pharmacokinetics ; Humans ; Indium Radioisotopes/chemistry ; Lutetium/chemistry ; Mice, Inbred BALB C ; Protein Binding ; Radioisotopes/chemistry ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/pharmacokinetics ; Rats ; Receptor, Cholecystokinin B/metabolism
Czasopismo naukowe
Tytuł :
Fetal biometry following in-utero exposure to dolutegravir-based or efavirenz-based antiretroviral therapy.
Autorzy :
Banda FM; Department of Paediatrics and Adolescent Health, Faculty of Medicine, University of Botswana.
Powis KM; Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health.; Departments of Internal Medicine and Pediatrics, Massachusetts General Hospital, Boston, Massachusetts.
Sun S; Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago.
Makhema J; Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Masasa G; Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Yee LM; Department of Obstetrics and Gynecology.
Jao J; Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.; Department of Pediatrics.; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
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Źródło :
AIDS (London, England) [AIDS] 2020 Dec 01; Vol. 34 (15), pp. 2336-2337.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Alkynes*/administration & dosage
Alkynes*/adverse effects
Benzoxazines*/administration & dosage
Benzoxazines*/adverse effects
Cyclopropanes*/administration & dosage
Cyclopropanes*/adverse effects
Fetus*/anatomy & histology
Fetus*/diagnostic imaging
Fetus*/drug effects
HIV Infections*/drug therapy
Heterocyclic Compounds, 3-Ring*/administration & dosage
Heterocyclic Compounds, 3-Ring*/adverse effects
Oxazines*/administration & dosage
Oxazines*/adverse effects
Piperazines*/administration & dosage
Piperazines*/adverse effects
Pregnancy Complications, Infectious*/drug therapy
Pregnancy Complications, Infectious*/virology
Pyridones*/administration & dosage
Pyridones*/adverse effects
Biometry ; Female ; HIV Integrase Inhibitors/administration & dosage ; HIV Integrase Inhibitors/adverse effects ; Humans ; Pregnancy ; Reverse Transcriptase Inhibitors/administration & dosage ; Reverse Transcriptase Inhibitors/adverse effects ; Ultrasonography, Prenatal
Czasopismo naukowe
Tytuł :
Doing More With Less: Review of Dolutegravir-Lamivudine, a Novel Single-Tablet Regimen for Antiretroviral-Naïve Adults With HIV-1 Infection.
Autorzy :
Santevecchi BA; University of Florida, Gainesville, FL, USA.
Miller S; University of Florida, Gainesville, FL, USA.
Childs-Kean LM; University of Florida, Gainesville, FL, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2020 Dec; Vol. 54 (12), pp. 1252-1259. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
HIV-1/*drug effects
Heterocyclic Compounds, 3-Ring/*therapeutic use
Lamivudine/*therapeutic use
Oxazines/*therapeutic use
Piperazines/*therapeutic use
Pyridones/*therapeutic use
Adult ; Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/adverse effects ; Clinical Trials as Topic ; Drug Administration Schedule ; Drug Combinations ; Female ; Heterocyclic Compounds, 3-Ring/administration & dosage ; Heterocyclic Compounds, 3-Ring/adverse effects ; Humans ; Lamivudine/administration & dosage ; Lamivudine/adverse effects ; Male ; Mutation ; Oxazines/administration & dosage ; Oxazines/adverse effects ; Piperazines/administration & dosage ; Piperazines/adverse effects ; Pyridones/administration & dosage ; Pyridones/adverse effects ; Tablets ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Brief Report: Durable Suppression and Low Rate of Virologic Failure 3 Years After Switch to Dolutegravir + Rilpivirine 2-Drug Regimen: 148-Week Results From the SWORD-1 and SWORD-2 Randomized Clinical Trials.
Autorzy :
van Wyk J; Global Medical, ViiV Healthcare, Brentford, United Kingdom.
Orkin C; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, United Kingdom.
Rubio R; HIV Unit, Department of Internal Medicine, Hospital Universitario 12 de Octubre, UCM, Madrid, Spain.
Bogner J; Division of Infectious Diseases, Munich University Hospital, Med IV, Munich, Germany.
Baker D; East Sydney Doctors, Darlinghurst, Sydney, Australia.
Khuong-Josses MA; Infectious Disease Unit, CHG-Hôpital Delafontaine, Saint Denis Cedex, France.
Parks D; Central West Clinical Research, St Louis, MO.
Angelis K; Biostatistics, GlaxoSmithKline, Uxbridge, United Kingdom.
Kahl LP; Clinical Development, ViiV Healthcare, Brentford, United Kingdom.
Matthews J; Clinical Development, ViiV Healthcare, Research Triangle Park, NC.
Wang R; Clinical Virology, ViiV Healthcare, Research Triangle Park, NC.
Underwood M; Clinical Virology, ViiV Healthcare, Research Triangle Park, NC.
Wynne B; Medicine Development, ViiV Healthcare, Research Triangle Park, NC.
Nascimento MC; Clinical Development, ViiV Healthcare, Brentford, United Kingdom.
Vandermeulen K; Global Regulatory and Compound Development, Janssen Pharmaceutica NV, Beerse, Belgium; and.
Gartland M; Medicine Development, ViiV Healthcare, Research Triangle Park, NC.
Smith KY; Research and Development, ViiV Healthcare, Research Triangle Park, NC.
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Źródło :
Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2020 Nov 01; Vol. 85 (3), pp. 325-330.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
HIV-1*
Anti-HIV Agents/*therapeutic use
HIV Infections/*drug therapy
Heterocyclic Compounds, 3-Ring/*therapeutic use
Rilpivirine/*therapeutic use
Anti-HIV Agents/administration & dosage ; Drug Administration Schedule ; Drug Combinations ; Female ; Heterocyclic Compounds, 3-Ring/administration & dosage ; Heterocyclic Compounds, 3-Ring/adverse effects ; Humans ; Male ; Middle Aged ; Rilpivirine/administration & dosage ; Rilpivirine/adverse effects ; Viral Load
Czasopismo naukowe
Tytuł :
Neuroendocrine Differentiation and Response to PSMA-Targeted Radioligand Therapy in Advanced Metastatic Castration-Resistant Prostate Cancer: A Single-Center Retrospective Study.
Autorzy :
Derlin T; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany .
Werner RA; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Lafos M; Institute of Pathology, Hannover Medical School, Hannover, Germany.
Henkenberens C; Department of Radiotherapy and Special Oncology, Hannover Medical School, Hannover, Germany; and.
von Klot CAJ; Department of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
Sommerlath Sohns JM; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Ross TL; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Bengel FM; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2020 Nov; Vol. 61 (11), pp. 1602-1606. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antigens, Surface/*metabolism
Chromogranin A/*blood
Dipeptides/*therapeutic use
Glutamate Carboxypeptidase II/*metabolism
Heterocyclic Compounds, 1-Ring/*therapeutic use
Peptide Fragments/*blood
Phosphopyruvate Hydratase/*blood
Prostatic Neoplasms, Castration-Resistant/*radiotherapy
Biomarkers ; Cell Differentiation ; Dipeptides/adverse effects ; Dipeptides/pharmacokinetics ; Heterocyclic Compounds, 1-Ring/adverse effects ; Heterocyclic Compounds, 1-Ring/pharmacokinetics ; Humans ; Male ; Neuroendocrine Cells/chemistry ; Neuroendocrine Cells/cytology ; Prostatic Neoplasms, Castration-Resistant/mortality ; Prostatic Neoplasms, Castration-Resistant/pathology ; Recombinant Proteins/blood
Czasopismo naukowe

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