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Tytuł :
Brief Report: Efficacy and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Females Living With HIV: An Integrated Analysis of 5 Trials.
Autorzy :
Orkin C; Ambrose King Centre, The Royal London Hospital, Barts Health NHS Trust, London, United Kingdom.
Ajana F; Centre Hospitalier de Tourcoing, Tourcoing, France.
Kityo C; Joint Clinical Research Centre, Kampala, Uganda.
Koenig E; Instituto Dominicano de Estudios Virologicos (IDEV), Santo Domingo, Dominican Republic; and.
Natukunda E; Joint Clinical Research Centre, Kampala, Uganda.
Gandhi-Patel B; Gilead Sciences, Foster City, CA.
Wang H; Gilead Sciences, Foster City, CA.
Liu Y; Gilead Sciences, Foster City, CA.
Wei X; Gilead Sciences, Foster City, CA.
White K; Gilead Sciences, Foster City, CA.
Makadzange T; Gilead Sciences, Foster City, CA.
Pikora C; Gilead Sciences, Foster City, CA.
McNicholl I; Gilead Sciences, Foster City, CA.
Collins SE; Gilead Sciences, Foster City, CA.
Brainard D; Gilead Sciences, Foster City, CA.
Chuck SK; Gilead Sciences, Foster City, CA.
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Źródło :
Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2021 Dec 01; Vol. 88 (4), pp. 393-398.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alanine/*therapeutic use
Amides/*therapeutic use
Anti-HIV Agents/*therapeutic use
Emtricitabine/*therapeutic use
HIV Infections/*drug therapy
HIV-1/*drug effects
Heterocyclic Compounds, 3-Ring/*therapeutic use
Piperazines/*therapeutic use
Pyridones/*therapeutic use
Tenofovir/*analogs & derivatives
Adenine/therapeutic use ; Adolescent ; Adult ; Aged ; Anti-HIV Agents/adverse effects ; Child ; Drug Combinations ; Female ; Heterocyclic Compounds, 4 or More Rings/therapeutic use ; Humans ; Middle Aged ; Tenofovir/therapeutic use ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Black Americans With HIV-1: A Randomized Phase 3b, Multicenter, Open-Label Study.
Autorzy :
Hagins D; Chatham CARE Center, Savannah, GA.
Kumar P; Department of Medicine, Georgetown University, Washington, DC.
Saag M; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Wurapa AK; Infectious Disease Specialists of Atlanta, Atlanta, GA.
Brar I; Department of Medicine, Henry Ford Hospital, Detroit, MI.
Berger D; Northstar Medical Center, Chicago, IL.
Osiyemi O; Triple O Research Institute, West Palm Beach, FL.
Hileman CO; Case Western Reserve University, Cleveland, OH.
Ramgopal MN; Midway Immunology and Research Center, Fort Pierce, FL.
McDonald C; Tarrant County Infectious Disease Associates, Fort Worth, TX; and.
Blair C; Gilead Sciences, Inc., Foster City, CA.
Andreatta K; Gilead Sciences, Inc., Foster City, CA.
Collins SE; Gilead Sciences, Inc., Foster City, CA.
Brainard DM; Gilead Sciences, Inc., Foster City, CA.
Martin H; Gilead Sciences, Inc., Foster City, CA.
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Corporate Authors :
BRAAVE2020 Investigators
Źródło :
Journal of acquired immune deficiency syndromes (1999) [J Acquir Immune Defic Syndr] 2021 Sep 01; Vol. 88 (1), pp. 86-95.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Alanine/*therapeutic use
Amides/*therapeutic use
Anti-HIV Agents/*therapeutic use
Emtricitabine/*therapeutic use
HIV Infections/*drug therapy
HIV-1/*drug effects
Heterocyclic Compounds, 3-Ring/*therapeutic use
Piperazines/*therapeutic use
Pyridones/*therapeutic use
Tenofovir/*analogs & derivatives
Adenine/therapeutic use ; Adolescent ; Adult ; African Americans ; Aged ; Drug Combinations ; Female ; HIV Infections/ethnology ; HIV Seropositivity ; HIV-1/genetics ; HIV-1/isolation & purification ; Heterocyclic Compounds, 4 or More Rings/therapeutic use ; Humans ; Male ; Middle Aged ; RNA/therapeutic use ; Tenofovir/therapeutic use ; United States/epidemiology ; Viral Load/drug effects
Czasopismo naukowe
Tytuł :
Tandem construction of biological relevant aliphatic 5-membered N-heterocycles.
Autorzy :
Łowicki D; Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614, Poznan, Poland.
Przybylski P; Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614, Poznan, Poland. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2022 May 05; Vol. 235, pp. 114303. Date of Electronic Publication: 2022 Mar 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heterocyclic Compounds*/chemistry
Heterocyclic Compounds*/pharmacology
Chemistry, Pharmaceutical ; Nitrogen/chemistry
Czasopismo naukowe
Tytuł :
Impact of mobilization regimen on multiday collection of peripheral blood CD34+ cells by large volume leukapheresis.
Autorzy :
Siddiqui I; Department of Pathology, Ohio State University, Columbus, Ohio, USA.
Shmookler A; Department of Pathology, Anatomy, and Laboratory Medicine, West Virginia University, Morgantown, West Virginia, USA.
Biller E; Department of Pathology, Ohio State University, Columbus, Ohio, USA.
Hardy T; Department of Pathology, Ohio State University, Columbus, Ohio, USA.
Hartage R; Department of Pathology, Ohio State University, Columbus, Ohio, USA.
Losos M; Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital, Cincinnati, Ohio, USA.
Chen J; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas, USA.
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Źródło :
Transfusion [Transfusion] 2022 Apr; Vol. 62 (4), pp. 857-862. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cyclams*
Heterocyclic Compounds*/pharmacology
Heterocyclic Compounds*/therapeutic use
Multiple Myeloma*
Antigens, CD34/metabolism ; Benzylamines/therapeutic use ; Granulocyte Colony-Stimulating Factor/pharmacology ; Granulocyte Colony-Stimulating Factor/therapeutic use ; Hematopoietic Stem Cell Mobilization/methods ; Humans ; Leukapheresis
Czasopismo naukowe
Tytuł :
Structure simplification of the Securinine skeleton reveals the importance of BCD ring system for the cytotoxic activity on HCT116 and HL60 cell lines.
Autorzy :
Le Roch M; ISCR UMR CNRS 6226, Université de Rennes 1 - Faculté de Pharmacie, Laboratoire de Chimie Thérapeutique, 2 Avenue du Pr Léon Bernard, F-35000 Rennes, France.
Afonso D; ISCR UMR CNRS 6226, Université de Rennes 1 - Faculté de Pharmacie, Laboratoire de Chimie Thérapeutique, 2 Avenue du Pr Léon Bernard, F-35000 Rennes, France.
Chirkin E; Institut Pasteur, Collection des Cyanobactéries, Département de Microbiologie, 25-28 rue du Docteur Roux, 75015 Paris, France.
Guillory X; ISCR UMR CNRS 6226, Université de Rennes 1 - Faculté de Pharmacie, Laboratoire de Chimie Thérapeutique, 2 Avenue du Pr Léon Bernard, F-35000 Rennes, France; INSERM U1242, Université de Rennes 1, Rue de la Bataille Flandres Dunkerque, F-35000 Rennes, France.
Porée FH; ISCR UMR CNRS 6226, Université de Rennes 1 - Faculté de Pharmacie, Laboratoire de Chimie Thérapeutique, 2 Avenue du Pr Léon Bernard, F-35000 Rennes, France. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Mar 15; Vol. 58, pp. 116658. Date of Electronic Publication: 2022 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Azepines/*pharmacology
Heterocyclic Compounds, Bridged-Ring/*pharmacology
Lactones/*pharmacology
Piperidines/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Azepines/chemical synthesis ; Azepines/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Density Functional Theory ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; HCT116 Cells ; HL-60 Cells ; Heterocyclic Compounds, Bridged-Ring/chemical synthesis ; Heterocyclic Compounds, Bridged-Ring/chemistry ; Humans ; Lactones/chemical synthesis ; Lactones/chemistry ; Molecular Conformation ; Piperidines/chemical synthesis ; Piperidines/chemistry ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Recent Progress in the Synthesis of Heterocycles based on 1,3-diketones.
Autorzy :
Talbi S; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
Dib M; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
Bouissane L; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
Abderrafia H; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
Rabi S; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
Khouili M; Laboratoire de Chimie Organique et Analytique, Équipe de Chimie Organique et Organométallique Appliquées, Faculté des Sciences et Techniques, Université Sultan Moulay Slimane, BP 523, 23000 Beni-Mellal, Morocco.
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Źródło :
Current organic synthesis [Curr Org Synth] 2022 Mar 03; Vol. 19 (2), pp. 220-245.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heterocyclic Compounds*
Ketones
Czasopismo naukowe
Tytuł :
Plerixafor on a WHIM - Promise or Fantasy of a New CXCR4 Inhibitor for This Rare, but Important Syndrome?
Autorzy :
Merati N; Division of Dermatology, McGill University Health Centre, Montréal, QC, Canada.
Sivachandran S; Division of Dermatology, McGill University Health Centre, Montréal, QC, Canada.
Jfri A; Division of Dermatology, McGill University Health Centre, Montréal, QC, Canada.
Ben-Shoshan M; Division of Allergy and Immunology, McGill University Health Centre, Montréal, QC, Canada.
Vinh DC; Division of Allergy and Immunology, McGill University Health Centre, Montréal, QC, Canada.; Division of Infectious Diseases, McGill University Health Centre, Montréal, QC, Canada.
Popradi G; Division of Hematology, McGill University Health Centre, Montréal, QC, Canada.
Litvinov IV; Division of Dermatology, McGill University Health Centre, Montréal, QC, Canada.
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Źródło :
Skin therapy letter [Skin Therapy Lett] 2022 Mar; Vol. 27 (2), pp. 1-5.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Agammaglobulinemia*/drug therapy
Heterocyclic Compounds*/pharmacology
Heterocyclic Compounds*/therapeutic use
Neutropenia*/drug therapy
Papillomavirus Infections*
Warts*/drug therapy
Warts*/pathology
Benzylamines ; Cyclams ; Fantasy ; Hematopoietic Stem Cell Mobilization ; Humans ; Primary Immunodeficiency Diseases ; Receptors, CXCR4/therapeutic use ; Syndrome
SCR Disease Name :
WHIM syndrome
Czasopismo naukowe
Tytuł :
Recent applications of seven-membered rings in drug design.
Autorzy :
Ouvry G; Evotec (U.K.) Ltd., 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, UK.
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Źródło :
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Mar 01; Vol. 57, pp. 116650. Date of Electronic Publication: 2022 Jan 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Design*
Enzyme Inhibitors/*pharmacology
Heterocyclic Compounds, 4 or More Rings/*pharmacology
Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Heterocyclic Compounds, 4 or More Rings/chemical synthesis ; Heterocyclic Compounds, 4 or More Rings/chemistry ; Molecular Structure
Czasopismo naukowe
Tytuł :
Antidiabetic with antilipidemic and antioxidant effects of flindersine by enhanced glucose uptake through GLUT4 translocation and PPARγ agonism in type 2 diabetic rats.
Autorzy :
Irudayaraj SS; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600 034, India; St. Xavier's College, Maharo, Dumka, 814110, Jharkhand, India.
Jincy J; Hillside College of Pharmacy and Research Center, Bangalore, 560062, India.
Sunil C; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600 034, India. Electronic address: .
Duraipandiyan V; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600 034, India. Electronic address: .
Ignacimuthu S; Xavier Research Foundation, St. Xavier's College, Palayamkottai, 627 002, Tamil Nadu, India.
Chandramohan G; Department of Community Health Sciences, College of Applied Medical Sciences,King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Packiam SM; Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai, 600 034, India; Department of Advanced Zoology and Biotechnology, Loyola College, Chennai-600 034, India.
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 Mar 01; Vol. 285, pp. 114883. Date of Electronic Publication: 2021 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2/*chemically induced
Diabetes Mellitus, Type 2/*drug therapy
Glucose Transporter Type 4/*metabolism
Heterocyclic Compounds, 3-Ring/*pharmacology
Hypoglycemic Agents/*pharmacology
PPAR gamma/*agonists
Animals ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Blood Glucose/drug effects ; Catalase ; Diabetes Mellitus, Experimental ; Diet, High-Fat/adverse effects ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Glucose/metabolism ; Glucose Transporter Type 4/genetics ; Glutathione Peroxidase ; Heterocyclic Compounds, 3-Ring/administration & dosage ; Heterocyclic Compounds, 3-Ring/chemistry ; Hypoglycemic Agents/chemistry ; Hypolipidemic Agents/chemistry ; Hypolipidemic Agents/pharmacology ; Male ; Molecular Structure ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Phytotherapy ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Rats ; Rats, Wistar ; Rutaceae/chemistry ; Superoxide Dismutase
Czasopismo naukowe
Tytuł :
Release mechanism between sarcoplasmic protein-bound and free heterocyclic amines and the effects of dietary additives using an in-vitro digestion model.
Autorzy :
Xue C; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Chen Q; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
He Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Qin F; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Wang Z; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
Chen J; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, Jiangsu 214122, China.
Zeng M; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, Jiangsu 214122, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2022 May 30; Vol. 377, pp. 131993. Date of Electronic Publication: 2022 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Amines*
Heterocyclic Compounds*
Carbolines ; Diet ; Digestion ; Food ; Harmine
Czasopismo naukowe
Tytuł :
Coordination-Controlled Nickel-Catalyzed Benzylic Allylation of Unactivated Electron-Deficient Heterocycles.
Autorzy :
Zhang P; Department of Chemistry, Yale University, 225 Prospect Street, PO Box 208107, New Haven, CT 06511, USA.
Wang J; Department of Chemistry, Yale University, 225 Prospect Street, PO Box 208107, New Haven, CT 06511, USA.
Robertson ZR; Department of Chemistry, Yale University, 225 Prospect Street, PO Box 208107, New Haven, CT 06511, USA.
Newhouse TR; Department of Chemistry, Yale University, 225 Prospect Street, PO Box 208107, New Haven, CT 06511, USA.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 May 23; Vol. 61 (22), pp. e202200602. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*/chemistry
Nickel*/chemistry
Catalysis ; Electrons ; Nitrogen
Czasopismo naukowe
Tytuł :
Overcoming Spectral Dependence: A General Strategy for Developing Far-Red and Near-Infrared Ultra-Fluorogenic Tetrazine Bioorthogonal Probes.
Autorzy :
Mao W; Huaxi MR Research Center, Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Huaxi Research Building, 001 4th Keyuan road, 610041, Chengdu, China.
Chi W; Fluorescence Research Group, Singapore University of Technology and Design, 8 Somapah Road, 487372, Singapore, Singapore.
He X; Huaxi MR Research Center, Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Huaxi Research Building, 001 4th Keyuan road, 610041, Chengdu, China.
Wang C; Fluorescence Research Group, Singapore University of Technology and Design, 8 Somapah Road, 487372, Singapore, Singapore.
Wang X; Huaxi MR Research Center, Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Huaxi Research Building, 001 4th Keyuan road, 610041, Chengdu, China.
Yang H; Huaxi MR Research Center, Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Huaxi Research Building, 001 4th Keyuan road, 610041, Chengdu, China.
Liu X; Fluorescence Research Group, Singapore University of Technology and Design, 8 Somapah Road, 487372, Singapore, Singapore.
Wu H; Huaxi MR Research Center, Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Huaxi Research Building, 001 4th Keyuan road, 610041, Chengdu, China.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 May 23; Vol. 61 (22), pp. e202117386. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*/chemistry
Fluorescence ; Fluorescent Dyes/chemistry
Czasopismo naukowe
Tytuł :
A Kinetic and Fluorogenic Enhancement Strategy for Labeling of Nucleic Acids.
Autorzy :
Loehr MO; Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montréal, Québec, H3A 0B8, Canada.
Luedtke NW; Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montréal, Québec, H3A 0B8, Canada.; Department of Pharmacology and Therapeutics, McGill University, 3655 Prom. Sir William Osler, Montréal, Québec H3G 1Y6, Canada.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 May 23; Vol. 61 (22), pp. e202112931. Date of Electronic Publication: 2022 Mar 30.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*
Nucleic Acids*
Acridines ; Cycloaddition Reaction ; DNA
Czasopismo naukowe
Tytuł :
BRD4 inhibitor MZ1 exerts anti-cancer effects by targeting MYCN and MAPK signaling in neuroblastoma.
Autorzy :
Zhang X; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; Department of Pediatric Surgery, The First People's Hospital of Kunshan, Suzhou, 215300, China.
Guo X; Medical College of Soochow University, Suzhou, 215123, Jiangsu, China.
Zhuo R; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu, 215025, PR China.
Tao Y; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Liang W; Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu, 215025, PR China.
Yang R; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu, 215025, PR China.
Chen Y; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; School of Basic Medicine and Biological Sciences, Soochow University, Suzhou, 215003, China.
Cao H; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; Department of Pediatrics, The Affiliated Hospital of Yangzhou University, Yangzhou, 225000, Jiangsu, China.
Jia S; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; School of Basic Medicine and Biological Sciences, Soochow University, Suzhou, 215003, China.
Yu J; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Liao X; School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200000, China.
Li X; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Fang F; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Li G; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Wu D; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Xu Y; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Li Z; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China.
Pan J; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China. Electronic address: .
Wang J; Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, 215003, China; Department of Pediatric Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu, 215025, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 May 14; Vol. 604, pp. 63-69. Date of Electronic Publication: 2022 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins*/antagonists & inhibitors
Dipeptides*/pharmacology
Heterocyclic Compounds, 3-Ring*/pharmacology
N-Myc Proto-Oncogene Protein*/genetics
N-Myc Proto-Oncogene Protein*/metabolism
Neuroblastoma*/metabolism
Transcription Factors*/antagonists & inhibitors
Transcription Factors*/metabolism
Cell Line, Tumor ; Child ; Gene Expression Regulation, Neoplastic ; Humans ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism
Czasopismo naukowe
Tytuł :
Colorimetric determination of tetracyclines based on aptamer-mediated dual regulation of gold nanoparticle aggregation and in situ silver metallization.
Autorzy :
Liu D; School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China. .
Huang P; School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China. .
Wu FY; School of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, China. .
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Źródło :
Analytical methods : advancing methods and applications [Anal Methods] 2022 May 13; Vol. 14 (18), pp. 1803-1809. Date of Electronic Publication: 2022 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*
Metal Nanoparticles*
Anti-Bacterial Agents ; Colorimetry/methods ; Gold ; Oligonucleotides ; Silver ; Tetracyclines
Czasopismo naukowe
Tytuł :
Uncovering the Key Role of Distortion in Bioorthogonal Tetrazine Tools That Defy the Reactivity/Stability Trade-Off.
Autorzy :
Svatunek D; Institute of Applied Synthetic Chemistry, TU Wien 1060 Vienna, Austria.
Wilkovitsch M; Institute of Applied Synthetic Chemistry, TU Wien 1060 Vienna, Austria.
Hartmann L; Institute of Applied Synthetic Chemistry, TU Wien 1060 Vienna, Austria.
Houk KN; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles 90095, United States.
Mikula H; Institute of Applied Synthetic Chemistry, TU Wien 1060 Vienna, Austria.
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Źródło :
Journal of the American Chemical Society [J Am Chem Soc] 2022 May 11; Vol. 144 (18), pp. 8171-8177. Date of Electronic Publication: 2022 May 02.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*/chemistry
Cycloaddition Reaction ; Electrons ; Kinetics
Czasopismo naukowe
Tytuł :
Peroxymonosulfate Activation on Synergistically Enhanced Single-Atom ) Ruthenium(II) Derivative.
Autorzy :
Wu Z; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Wang C; Institute of Modern Physics, Chinese Academy of Science, Lanzhou 730000, P. R. China.; Advanced Energy Science and Technology Guangdong Laboratory, Huizhou 516000, P. R. China.
Luo Z; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Qin Y; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Wang X; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Wen J; Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, Hubei Engineering Technology Research Center of Optoelectronic and New Energy Materials, Wuhan Institute of Technology, Wuhan 430205, P. R. China.
Hu L; Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, Hubei Engineering Technology Research Center of Optoelectronic and New Energy Materials, Wuhan Institute of Technology, Wuhan 430205, P. R. China.
Gu W; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
Zhu C; Key Laboratory of Pesticides and Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensing Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.
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Źródło :
Analytical chemistry [Anal Chem] 2022 May 10; Vol. 94 (18), pp. 6866-6873. Date of Electronic Publication: 2022 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*
Ruthenium*
Cobalt ; Humans ; Luminescence ; Luminescent Measurements/methods ; Peroxides
Czasopismo naukowe
Tytuł :
Design and Synthesis of Tunable Chiral 2,2'-Bipyridine Ligands: Application to the Enantioselective Nickel-Catalyzed Reductive Arylation of Aldehydes.
Autorzy :
Zhang S; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Perveen S; School of Chemistry, Xi'an Jiaotong University, Xi'an, Shaanxi 710049, China.
Ouyang Y; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Xu L; School of Chemistry and Chemical Engineering/Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi, 832003, China.
Yu T; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Zhao M; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Wang L; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Song P; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Li P; Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.; State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 May 09; Vol. 61 (20), pp. e202117843. Date of Electronic Publication: 2022 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Aldehydes*/chemistry
Heterocyclic Compounds*
2,2'-Dipyridyl ; Catalysis ; Ligands ; Nickel/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Study of Renal Accumulation of Targeted Polycations in Acute Kidney Injury.
Autorzy :
Tang W; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Panja S; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Jogdeo CM; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Tang S; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Yu A; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
Oupický D; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.
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Źródło :
Biomacromolecules [Biomacromolecules] 2022 May 09; Vol. 23 (5), pp. 2064-2074. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury*/drug therapy
Acute Kidney Injury*/metabolism
Heterocyclic Compounds*
Reperfusion Injury*/drug therapy
Reperfusion Injury*/metabolism
Animals ; Female ; Hematopoietic Stem Cell Mobilization ; Humans ; Kidney/metabolism ; Male ; Mice ; Polyelectrolytes ; Polymers/metabolism ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Lanthanide coordination polymer nanoparticles as a ratiometric fluorescence sensor for real-time and visual detection of tetracycline by a smartphone and test paper based on the analyte-triggered antenna effect and inner filter effect.
Autorzy :
Yin S; Key Laboratory of Environmental Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, 310058, China.
Tong C; Key Laboratory of Environmental Remediation and Ecological Health, Ministry of Education, College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, 310058, China. Electronic address: .
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2022 May 08; Vol. 1206, pp. 339809. Date of Electronic Publication: 2022 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Heterocyclic Compounds*
Lanthanoid Series Elements*
Nanoparticles*
Anti-Bacterial Agents/analysis ; Fluorescent Dyes ; Polymers ; Smartphone ; Spectrometry, Fluorescence ; Tetracycline ; Water
Czasopismo naukowe

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