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Wyszukujesz frazę ""HETEROCYCLIC compounds"" wg kryterium: Temat


Tytuł:
Emerging roles of SIRT1 activator, SRT2104, in disease treatment.
Autorzy:
Chang N; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China.
Li J; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China.
Lin S; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China.
Zhang J; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China.
Zeng W; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China. .
Ma G; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China. .
Wang Y; Shunde Women and Children's Hospital, Guangdong Medical University, Foshan, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 06; Vol. 14 (1), pp. 5521. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Sirtuin 1*
Heterocyclic Compounds, 2-Ring*/pharmacology
Heterocyclic Compounds, 2-Ring*/therapeutic use
Databases, Factual ; PubMed
Czasopismo naukowe
Tytuł:
Facile One-Pot Synthesis and Anti-Microbial Activity of Novel 1,4-Dihydropyridine Derivatives in Aqueous Micellar Solution under Microwave Irradiation.
Autorzy:
Goswami A; Medicinal and Natural Product Laboratory, Department of Chemistry, Chandigarh University, Mohali 140413, Punjab, India.
Kaur N; Medicinal and Natural Product Laboratory, Department of Chemistry, Chandigarh University, Mohali 140413, Punjab, India.
Kaur M; Medicinal and Natural Product Laboratory, Department of Chemistry, Chandigarh University, Mohali 140413, Punjab, India.
Singh K; Department of Chemistry, Punjabi University, Patiala 147002, Punjab, India.
Sohal HS; Medicinal and Natural Product Laboratory, Department of Chemistry, Chandigarh University, Mohali 140413, Punjab, India.
Han H; Department of Chemistry and Biochemistry, University of Nevada Las Vegas, 4505 S. Maryland Parkway, Box 454003, Las Vegas, NV 89154, USA.
Bhowmik PK; Department of Chemistry and Biochemistry, University of Nevada Las Vegas, 4505 S. Maryland Parkway, Box 454003, Las Vegas, NV 89154, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 01; Vol. 29 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Dihydropyridines*
Heterocyclic Compounds*
Microwaves ; Aluminum
Czasopismo naukowe
Tytuł:
The efficacy and safety of deucravacitinib compared to methotrexate, in patients with vulvar lichen planus who have failed topical therapy with potent corticosteroids: a study protocol for a single-centre double-blinded randomised controlled trial.
Autorzy:
Wijaya M; Department of Dermatology, Royal North Shore Hospital, Reserve Rd, St Leonards, New South Wales, Australia. .; The University of Sydney, Northern Clinical School, St Leonards, New South Wales, Australia. .
Fischer G; Department of Dermatology, Royal North Shore Hospital, Reserve Rd, St Leonards, New South Wales, Australia.; The University of Sydney, Northern Clinical School, St Leonards, New South Wales, Australia.
Saunderson RB; Department of Dermatology, Royal North Shore Hospital, Reserve Rd, St Leonards, New South Wales, Australia.; The University of Sydney, Northern Clinical School, St Leonards, New South Wales, Australia.
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Źródło:
Trials [Trials] 2024 Mar 12; Vol. 25 (1), pp. 181. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Clinical Trial Protocol; Journal Article
MeSH Terms:
Dermatologic Agents*/adverse effects
Heterocyclic Compounds*
Lichen Planus*/chemically induced
Lichen Planus*/drug therapy
Female ; Humans ; Adrenal Cortex Hormones/adverse effects ; Australia ; Folic Acid ; Glucocorticoids ; Methotrexate/adverse effects ; Quality of Life ; Randomized Controlled Trials as Topic ; Tablets ; Treatment Outcome ; Adolescent ; Adult
Czasopismo naukowe
Tytuł:
Research progress of the chemokine/chemokine receptor axes in the oncobiology of multiple myeloma (MM).
Autorzy:
Du J; Department of Hematology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Lin Z; Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Fu XH; Department of Hematology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.
Gu XR; Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Lu G; Department of Hematology, Shengli Oilfield Central Hospital, Dongying, 257099, China. .
Hou J; Department of Hematology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 12; Vol. 22 (1), pp. 177. Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Multiple Myeloma*
Heterocyclic Compounds*
Humans ; Hematopoietic Stem Cell Mobilization ; Chemokines ; Signal Transduction ; Biomarkers
Czasopismo naukowe
Tytuł:
Silver and Gold Complexes with NHC-Ligands Derived from Caffeine: Catalytic and Pharmacological Activity.
Autorzy:
Mariconda A; Department of Science, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Iacopetta D; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
Sirignano M; Department of Chemistry and Biology 'A. Zambelli', University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
Ceramella J; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
D'Amato A; Department of Chemistry and Biology 'A. Zambelli', University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
Marra M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
Pellegrino M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
Sinicropi MS; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
Aquaro S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Via Pietro Bucci, 87036 Arcavacata di Rende, Italy.
Longo P; Department of Chemistry and Biology 'A. Zambelli', University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*
Heterocyclic Compounds*/chemistry
Coordination Complexes*/chemistry
Methane/*analogs & derivatives
Humans ; Silver/chemistry ; Gold/chemistry ; Caffeine ; Anti-Bacterial Agents/pharmacology ; Methane/chemistry
Czasopismo naukowe
Tytuł:
Virologic outcomes on dolutegravir-, atazanavir-, or efavirenz-based ART in urban Zimbabwe: A longitudinal study.
Autorzy:
Shamu T; Newlands Clinic, Harare, Zimbabwe.; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.; Graduate School of Health Sciences, University of Bern, Bern, Switzerland.
Egger M; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.; Centre for Infectious Disease Epidemiology and Research, School of Public Health, University of Cape Town, Cape Town, South Africa.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Mudzviti T; Newlands Clinic, Harare, Zimbabwe.; Department of Pharmacy and Pharmaceutical Sciences, University of Zimbabwe, Harare, Zimbabwe.
Chimbetete C; Newlands Clinic, Harare, Zimbabwe.
Manasa J; Innovation Hub, University of Zimbabwe, Harare, Zimbabwe.
Anderegg N; Newlands Clinic, Harare, Zimbabwe.; Centre for Infectious Disease Epidemiology and Research, School of Public Health, University of Cape Town, Cape Town, South Africa.
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Źródło:
PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0293162. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Piperazines*
Pyridones*
Alkynes*
Oxazines*
Heterocyclic Compounds, 3-Ring*
Cyclopropanes*
Humans ; Female ; Male ; Atazanavir Sulfate/therapeutic use ; Longitudinal Studies ; Zimbabwe ; Bayes Theorem ; Benzoxazines/therapeutic use ; Viral Load
Czasopismo naukowe
Tytuł:
Levistilide A Exerts a Neuroprotective Effect by Suppressing Glucose Metabolism Reprogramming and Preventing Microglia Polarization Shift: Implications for Parkinson's Disease.
Autorzy:
Zhang M; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Duan C; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Lin W; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Wu H; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Chen L; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Guo H; State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Yu M; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Liu Q; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Nie Y; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Wang H; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
Wang S; School of Medical Technology, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, West Area, Tuanbo New Town, Jinghai District, Tianjin 301617, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 19; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article
MeSH Terms:
Parkinson Disease*/drug therapy
Parkinson Disease*/metabolism
Neuroprotective Agents*/therapeutic use
Heterocyclic Compounds, Bridged-Ring*
Humans ; NF-kappa B/metabolism ; Microglia ; Lipopolysaccharides/pharmacology ; AMP-Activated Protein Kinases/metabolism ; Metabolic Reprogramming ; Anti-Inflammatory Agents/therapeutic use ; TOR Serine-Threonine Kinases/metabolism ; Glucose/metabolism
Czasopismo naukowe
Tytuł:
Sustainable remediation of chromium-contaminated soils: boosting radish growth with deashed biochar and strigolactone.
Autorzy:
Younis U; Botany Department, The Islamia University of Bahawalpur, Sub Campus Rahim Yar Khan, Rahim Yar Khan, Punjab, Pakistan.
Danish S; Department of Soil Science, Faculty of Agricultural Sciences and Technology, Bahauddin Zakariya University, Multan, Punjab, Pakistan. .
Datta R; Department of Geology and Pedology, Faculty of Forestry and Wood Technology, Mendel University in Brno, Zemedelska 1, Brno, 61300, Czech Republic. .
Alahmadi TA; Department of Pediatrics, College of Medicine and King Khalid University Hospital, King Saud University, Medical City, PO Box-2925, 11461, Riyadh, Saudi Arabia.
Ansari MJ; Department of Botany, Hindu College Moradabad (Mahatma Jyotiba Phule Rohilkhand University Bareilly), Moradabad, India.
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Źródło:
BMC plant biology [BMC Plant Biol] 2024 Feb 16; Vol. 24 (1), pp. 115. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Raphanus*
Soil Pollutants*
Heterocyclic Compounds, 3-Ring*
Lactones*
Chromium ; Chlorophyll A ; Ecosystem ; Charcoal ; Soil/chemistry
Czasopismo naukowe
Tytuł:
A pivotal bridging study of lurbinectedin as second-line therapy in Chinese patients with small cell lung cancer.
Autorzy:
Cheng Y; Department of Oncology, Jilin Cancer Hospital, Changchun, 130000, China. .
Wu C; Department of Oncology, Jilin Cancer Hospital, Changchun, 130000, China.
Wu L; Department of Thoracic Oncology, Hunan Cancer Hospital, Changsha, 410013, China.
Zhao J; Department of Thoracic Oncology, Beijing Cancer Hospital, Beijing, 100142, China.
Zhao Y; Department of Oncology, Henan Cancer Hospital, Zhengzhou, 450003, China.
Chen L; Department of Oncology, Jilin Cancer Hospital, Changchun, 130000, China.
Xin Y; Department of Oncology, Jilin Cancer Hospital, Changchun, 130000, China.
Zhang L; Department of Oncology, Jilin Cancer Hospital, Changchun, 130000, China.
Pan P; Department of Respiratory Disease, Xiangya Hospital Central South University, Changsha, 410008, China.
Li X; Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Li J; Department of Oncology, Sichuan Cancer Hospital, Chengdu, 610041, China.
Dong X; Center of Oncology, Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Tang K; Clinical Research Center of Luye Pharma Group Ltd, Luye Life Sciences Group, Beijing, 100080, China.
Gao E; Clinical Research Center of Luye Pharma Group Ltd, Luye Life Sciences Group, Beijing, 100080, China.
Yu F; School of Pharmacy, Yantai University, Yantai, 264005, China.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 13; Vol. 14 (1), pp. 3598. Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Multicenter Study
MeSH Terms:
Anemia*/etiology
Carbolines*/adverse effects
Heterocyclic Compounds, 4 or More Rings*/adverse effects
Lung Neoplasms*/pathology
Neutropenia*/drug therapy
Small Cell Lung Carcinoma*/pathology
Thrombocytopenia*/etiology
Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; China
Czasopismo naukowe
Tytuł:
Dolutegravir based therapy showed CD4 T cell count recovery and viral load suppression among ART naïve people living with HIV AIDS: a pilot evaluation.
Autorzy:
Gebremedhin T; University of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia.
Aynalem M; Department of Hematology and Immunohematology, University of Gondar, Gondar, Ethiopia.
Adem M; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
Geremew D; Department of Medical Laboratory Sciences, Immunology and Molecular Biology Unit, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Aleka Y; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia. .
Kiflie A; Department of Immunology and Molecular Biology, University of Gondar, Gondar, Ethiopia.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 08; Vol. 14 (1), pp. 3297. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Acquired Immunodeficiency Syndrome*/drug therapy
HIV Infections*
Anti-HIV Agents*/pharmacology
HIV-1*/genetics
Heterocyclic Compounds, 3-Ring*
Oxazines*
Piperazines*
Pyridones*
Humans ; Antiretroviral Therapy, Highly Active ; Prospective Studies ; Viral Load ; Pilot Projects ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes ; RNA/pharmacology
Czasopismo naukowe
Tytuł:
Efficacy and Safety of Omarigliptin, a Novel Once-Weekly Dipeptidyl Peptidase-4 Inhibitor, in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Autorzy:
Kamrul-Hasan ABM; Department of Endocrinology, Mymensingh Medical College, Mymensingh, Bangladesh.
Alam MS; Department of Medicine, Army Medical College Cumilla, Cumilla, Bangladesh.
Talukder SK; Department of Endocrinology, Rangpur Medical College, Rangpur, Bangladesh.
Dutta D; Department of Endocrinology, Center for Endocrinology, Diabetes, Arthritis and Rheumatism (CEDAR) Superspeciality Healthcare, New Delhi, India.
Selim S; Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
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Źródło:
Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2024 Feb; Vol. 39 (1), pp. 109-126. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
Dipeptidyl-Peptidase IV Inhibitors*/adverse effects
Diabetes Mellitus, Type 2*/complications
Hypoglycemia*/chemically induced
Hypoglycemia*/epidemiology
Heterocyclic Compounds, 2-Ring*
Pyrans*
Humans ; Glycated Hemoglobin ; Blood Glucose/analysis ; Hypoglycemic Agents/adverse effects ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use
Czasopismo naukowe
Tytuł:
The Overexpression of Zea mays Strigolactone Receptor Gene D14 Enhances Drought Resistance in Arabidopsis thaliana L.
Autorzy:
Zhang C; College of Life Sciences, Jilin Agricultural University, Changchun 130118, China.
Wang F; College of Life Sciences, Jilin Agricultural University, Changchun 130118, China.
Jiao P; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Liu J; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Zhang H; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Liu S; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Guan S; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
Ma Y; College of Agronomy, Jilin Agricultural University, Changchun 130118, China.; Joint International Research Laboratory of Modern Agricultural Technology, Ministry of Education, Jilin Agricultural University, Changchun 130118, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 22; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Arabidopsis*/metabolism
Arabidopsis Proteins*/genetics
Heterocyclic Compounds, 3-Ring*
Lactones*
Zea mays/genetics ; Zea mays/metabolism ; Drought Resistance ; Droughts ; Gene Expression Regulation, Plant ; Plants, Genetically Modified/genetics ; Plants, Genetically Modified/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism
Czasopismo naukowe
Tytuł:
Genetic Model Identification and Major QTL Mapping for Petiole Thickness in Non-Heading Chinese Cabbage.
Autorzy:
Liu G; Vegetables Engineering and Technology Research Center of Shaanxi Province, College of Horticulture, Northwest A & F University, Yangling, Xianyang 712100, China.
Li Y; Vegetables Engineering and Technology Research Center of Shaanxi Province, College of Horticulture, Northwest A & F University, Yangling, Xianyang 712100, China.
Si J; Vegetables Engineering and Technology Research Center of Shaanxi Province, College of Horticulture, Northwest A & F University, Yangling, Xianyang 712100, China.
Lu R; Vegetables Engineering and Technology Research Center of Shaanxi Province, College of Horticulture, Northwest A & F University, Yangling, Xianyang 712100, China.
Hui M; Vegetables Engineering and Technology Research Center of Shaanxi Province, College of Horticulture, Northwest A & F University, Yangling, Xianyang 712100, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 09; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Genetic*
Arabidopsis*
Heterocyclic Compounds, 3-Ring*
Adult ; Humans ; Chromosome Mapping ; Lactones ; Agriculture
Czasopismo naukowe
Tytuł:
Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment-Progresses in Their Use in Combined Cancer Therapy.
Autorzy:
Povo-Retana A; Instituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
Landauro-Vera R; Instituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
Alvarez-Lucena C; Instituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
Cascante M; Department of Biochemistry and Molecular Biomedicine-Institute of Biomedicine (IBUB), Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.; Department of Material Science and Physical Chemistry, Research Institute of Theoretical and Computational Chemistry (IQTCUB), University of Barcelona, 08028 Barcelona, Spain.
Boscá L; Instituto de Investigaciones Biomédicas Alberto Sols-Morreale (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Jan 09; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Tumor Microenvironment*
Ovarian Neoplasms*
Carbolines*
Heterocyclic Compounds, 4 or More Rings*
Adult ; Female ; Humans ; Trabectedin ; Neoplasm Recurrence, Local
Czasopismo naukowe
Tytuł:
Upadacitinib: Mechanism of action, clinical, and translational science.
Autorzy:
Mohamed MF; Clinical Pharmacology, AbbVie, North Chicago, Illinois, USA.
Bhatnagar S; Clinical Pharmacology, AbbVie, North Chicago, Illinois, USA.
Parmentier JM; Precision Medicine, AbbVie, North Chicago, Illinois, USA.
Nakasato P; Medical Affairs, AbbVie, North Chicago, Illinois, USA.
Wung P; Clinical Development, AbbVie, North Chicago, Illinois, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13688. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Arthritis, Rheumatoid*/drug therapy
Spondylitis, Ankylosing*/drug therapy
Janus Kinase Inhibitors*/therapeutic use
Heterocyclic Compounds, 3-Ring*
United States ; Humans ; Translational Science, Biomedical ; Janus Kinases/therapeutic use
Czasopismo naukowe
Tytuł:
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
Autorzy:
Frechen S; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Ince I; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Dallmann A; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Gerisch M; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Jungmann NA; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Becker C; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Lobmeyer M; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Trujillo ME; Merck & Co., Inc., Rahway, New Jersey, USA.
Xu S; Merck & Co., Inc., Rahway, New Jersey, USA.
Burghaus R; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Meyer M; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 79-92. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Mefenamic Acid*
Glucuronosyltransferase*/metabolism
Heterocyclic Compounds, 2-Ring*
Pyrimidines*
Humans ; Atazanavir Sulfate ; Drug Interactions
Czasopismo naukowe
Tytuł:
Significant Differences in the Effects of Nitrogen Doping on Pristine Biochar and Graphene-like Biochar for the Adsorption of Tetracycline.
Autorzy:
Rong L; College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China.; School of Life Science, Jinggangshan University, 28 Xueyuan Road, Ji'an 343009, China.
Wu L; College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China.
Zhang T; School of Life Science, Jinggangshan University, 28 Xueyuan Road, Ji'an 343009, China.
Hu C; School of Life Science, Jinggangshan University, 28 Xueyuan Road, Ji'an 343009, China.
Tang H; School of Life Science, Jinggangshan University, 28 Xueyuan Road, Ji'an 343009, China.
Pan H; College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China.
Zou X; School of Life Science, Jinggangshan University, 28 Xueyuan Road, Ji'an 343009, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Dec 27; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Graphite*
Heterocyclic Compounds*
Environmental Pollutants*
Charcoal*
Adsorption ; Tetracycline ; Anti-Bacterial Agents ; Nitrogen ; Transcription Factors
Czasopismo naukowe
Tytuł:
Virological Findings and Treatment Outcomes of Cases That Developed Dolutegravir Resistance in Malawi's National HIV Treatment Program.
Autorzy:
Kanise H; Partners in Hope, Lilongwe P.O. Box 302, Malawi.
van Oosterhout JJ; Partners in Hope, Lilongwe P.O. Box 302, Malawi.; Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Bisani P; The Lighthouse Trust, Lilongwe P.O. Box 106, Malawi.
Songo J; Partners in Hope, Lilongwe P.O. Box 302, Malawi.
Matola BW; Directorate of HIV, STI and Viral Hepatitis, Ministry of Health, Lilongwe P.O. Box 30377, Malawi.
Chipungu C; Partners in Hope, Lilongwe P.O. Box 302, Malawi.
Simon K; Baylor College of Medicine Children's Foundation-Malawi, Lilongwe P.O. Box 110, Malawi.; Baylor College of Medicine, Houston, TX 77030, USA.
Cox C; Baylor College of Medicine Children's Foundation-Malawi, Lilongwe P.O. Box 110, Malawi.; Baylor College of Medicine, Houston, TX 77030, USA.
Hosseinipour MC; University of North Carolina Project Malawi, Lilongwe Private Bag A-104, Malawi.; Department of Medicine, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC 27599, USA.
Sagno JB; DREAM, Communion of St. Egidio, Blantyre, P.O. Box 30355, Malawi.
Hoffman RM; Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Wallrauch C; The Lighthouse Trust, Lilongwe P.O. Box 106, Malawi.
Phiri S; Partners in Hope, Lilongwe P.O. Box 302, Malawi.; School of Global and Public Health, Kamuzu University of Health Sciences, Lilongwe P.O. Box 30184, Malawi.
Steegen K; Department of Haematology & Molecular Medicine, National Health Laboratory Service, Johannesburg 2131, South Africa.; Department of Haematology & Molecular Medicine, University of the Witwatersrand, Johannesburg 2017, South Africa.
Jahn A; Directorate of HIV, STI and Viral Hepatitis, Ministry of Health, Lilongwe P.O. Box 30377, Malawi.; Department of Global Health, University of Washington, Seattle, WA 98195, USA.
Nyirenda R; Directorate of HIV, STI and Viral Hepatitis, Ministry of Health, Lilongwe P.O. Box 30377, Malawi.
Heller T; The Lighthouse Trust, Lilongwe P.O. Box 106, Malawi.; International Training and Education Center for Health (ITECH), University of Washington, Seattle, WA 98104-2499, USA.
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Źródło:
Viruses [Viruses] 2023 Dec 23; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 23.
Typ publikacji:
Review; Journal Article
MeSH Terms:
HIV*
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Heterocyclic Compounds, 3-Ring*
Oxazines*
Piperazines*
Pyridones*
Humans ; Malawi/epidemiology ; Treatment Outcome ; Integrases
Czasopismo naukowe
Tytuł:
Stem cell collection after lenalidomide, bortezomib and dexamethasone plus elotuzumab or isatuximab in newly diagnosed multiple myeloma patients: a single centre experience from the GMMG-HD6 and -HD7 trials.
Autorzy:
Kauer J; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany.
Freundt EP; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Schmitt A; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Weinhold N; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Mai EK; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; GMMG Study Group at University Hospital Heidelberg, Heidelberg, Germany.
Müller-Tidow C; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany.; National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany.
Goldschmidt H; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; GMMG Study Group at University Hospital Heidelberg, Heidelberg, Germany.; National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany.
Raab MS; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; National Centre for Tumour Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany.
Kriegsmann K; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.; Laborarztpraxis, Laborarztpraxis Rhein-Main MVZ GbR, Limbach Gruppe SE, Frankfurt Am Main, Germany.
Sauer S; Department of Haematology, Oncology and Rheumatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. .
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Źródło:
BMC cancer [BMC Cancer] 2023 Nov 21; Vol. 23 (1), pp. 1132. Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial
MeSH Terms:
Heterocyclic Compounds*/therapeutic use
Multiple Myeloma*/drug therapy
Multiple Myeloma*/diagnosis
Peripheral Blood Stem Cell Transplantation*
Humans ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Bortezomib/therapeutic use ; Dexamethasone/therapeutic use ; Hematopoietic Stem Cell Mobilization/methods ; Lenalidomide/therapeutic use ; Transplantation, Autologous
Czasopismo naukowe
Tytuł:
Evaluation of Biological Equivalence for Generic Tulathromycin Injections in Cattle.
Autorzy:
Kang J; Animal Disease Diagnosis Division, Animal and Plant Quarantine Agency (APQA), Ministry of Agriculture, Food and Rural Affairs, 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.
Chae H; Animal Disease Diagnosis Division, Animal and Plant Quarantine Agency (APQA), Ministry of Agriculture, Food and Rural Affairs, 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.
Jeong S; Veterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency (APQA), Ministry of Agriculture, Food and Rural Affairs, 177, Hyeoksin 8-ro, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea.
Pervin R; Department of Microbiology and Immunology, College of Medicine, University of Illinois Chicago, 835 S. Wolcott Ave (MC790), Chicago, IL 60612, USA.
Hossain MA; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois Chicago, 833 S. Wood St. (MC964), Chicago, IL 60612, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 13; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article
MeSH Terms:
Tandem Mass Spectrometry*
Heterocyclic Compounds*
Cattle ; Animals ; Chromatography, Liquid ; Disaccharides ; Drugs, Generic/pharmacokinetics ; Area Under Curve ; Cross-Over Studies
Czasopismo naukowe

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