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Tytuł :
TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice.
Autorzy :
Johanna I; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hernández-López P; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Heijhuurs S; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Bongiovanni L; Department of Pathobiology, Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
de Bruin A; Department of Pathobiology, Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Beringer D; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
van Dooremalen S; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Shultz LD; Department of Immunology, The Jackson Laboratory, Bar Harbor, Maine, USA.
Ishikawa F; Laboratory for Human Disease Models, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Sebestyen Z; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Straetemans T; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
Kuball J; Department of Hematology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Jun; Vol. 107 (6), pp. 1069-1079. Date of Electronic Publication: 2020 Feb 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
HLA-A24 Antigen/*genetics
Receptors, Antigen, T-Cell, gamma-delta/*genetics
Soft Tissue Neoplasms/*prevention & control
T-Lymphocytes, Regulatory/*immunology
Adoptive Transfer ; Animals ; Cell Engineering ; Gene Expression ; Graft vs Host Disease/genetics ; Graft vs Host Disease/immunology ; Graft vs Host Disease/prevention & control ; HLA-A24 Antigen/immunology ; Humans ; Immunotherapy/methods ; K562 Cells ; Male ; Mice ; Mice, Transgenic ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Signal Transduction ; Soft Tissue Neoplasms/genetics ; Soft Tissue Neoplasms/immunology ; Soft Tissue Neoplasms/pathology ; T-Lymphocytes, Regulatory/pathology ; T-Lymphocytes, Regulatory/transplantation ; Transduction, Genetic ; Whole-Body Irradiation
Czasopismo naukowe
Tytuł :
Identification of an HLA-A*24:02-restricted α-fetoprotein signal peptide-derived antigen and its specific T-cell receptor for T-cell immunotherapy.
Autorzy :
Li Z; School of Life Sciences, University of Science and Technology of China, Hefei, China.; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Gong H; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Liu Q; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Wu W; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Cheng J; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Mei Y; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Chen Y; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Zheng H; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Yu X; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Zhong S; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.
Li Y; Guangdong Xiangxue Life Sciences, Ltd., Guangzhou, China.; State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
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Źródło :
Immunology [Immunology] 2020 Apr; Vol. 159 (4), pp. 384-392. Date of Electronic Publication: 2020 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Neoplasm/*immunology
HLA-A24 Antigen/*immunology
Oligopeptides/*immunology
Protein Sorting Signals/*genetics
Receptors, Antigen, T-Cell/*immunology
alpha-Fetoproteins/*immunology
Amino Acid Sequence ; Antigens, Neoplasm/chemistry ; Antigens, Neoplasm/genetics ; Binding Sites ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/immunology ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/therapy ; Cell Line, Tumor ; Coculture Techniques ; Gene Expression ; HLA-A24 Antigen/chemistry ; HLA-A24 Antigen/genetics ; Healthy Volunteers ; Hep G2 Cells ; Humans ; Immunotherapy/methods ; Liver Neoplasms/genetics ; Liver Neoplasms/immunology ; Liver Neoplasms/pathology ; Liver Neoplasms/therapy ; Oligopeptides/chemistry ; Oligopeptides/genetics ; Protein Binding ; Receptors, Antigen, T-Cell/chemistry ; Receptors, Antigen, T-Cell/genetics ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/pathology ; Transfection ; alpha-Fetoproteins/chemistry ; alpha-Fetoproteins/genetics
Czasopismo naukowe
Tytuł :
HLA-A∗24:02 associated with lamotrigine-induced cutaneous adverse drug reactions: A systematic review and meta-analysis.
Autorzy :
Li W; Department of Pharmacy.
Wang J; Department of Pharmacy.
Lin H; Department of Pharmacy.
Shen G; Department of Surgery, Ningbo Municipal Hospital of Traditional Chinese Medicine, Ningbo, Zhejiang, PR China.
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Źródło :
Medicine [Medicine (Baltimore)] 2020 Dec 24; Vol. 99 (52), pp. e23929.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Drug Eruptions/*genetics
HLA-A24 Antigen/*genetics
Lamotrigine/*adverse effects
Anticonvulsants/adverse effects ; Anticonvulsants/pharmacology ; Humans ; Lamotrigine/pharmacology ; Pharmacogenomic Variants ; Risk Factors
Czasopismo naukowe
Tytuł :
Targeting mutant p53-expressing tumours with a T cell receptor-like antibody specific for a wild-type antigen.
Autorzy :
Low L; Singapore Immunology Network, Agency for Science, Technology and Research, 8A Biomedical Grove, Singapore, 138648, Singapore.
Goh A; Singapore Immunology Network, Agency for Science, Technology and Research, 8A Biomedical Grove, Singapore, 138648, Singapore.
Koh J; School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, 599489, Singapore.
Lim S; School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, 535 Clementi Road, Singapore, 599489, Singapore.
Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research, 8A Biomedical Grove, Singapore, 138648, Singapore. .
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Źródło :
Nature communications [Nat Commun] 2019 Nov 26; Vol. 10 (1), pp. 5382. Date of Electronic Publication: 2019 Nov 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies/*pharmacology
Antineoplastic Agents, Immunological/*pharmacology
HLA-A24 Antigen/*immunology
Receptors, Antigen, T-Cell/*immunology
Tumor Suppressor Protein p53/*genetics
Animals ; Antibodies/genetics ; Antibodies/immunology ; Antibody-Dependent Cell Cytotoxicity ; Antineoplastic Agents, Immunological/adverse effects ; Cell Line, Tumor ; Cross Reactions ; Cytotoxicity, Immunologic ; Epitopes ; HLA-A24 Antigen/genetics ; HLA-A24 Antigen/metabolism ; Humans ; Mice, Transgenic ; Molecular Targeted Therapy/methods ; Mutation ; Tumor Suppressor Protein p53/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients.
Autorzy :
Daiko H; Esophageal Surgery Division, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. .
Marafioti T; Department of Cellular Pathology, University College London Hospital, London, UK.
Fujiwara T; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Shirakawa Y; Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nakatsura T; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
Kato K; Gastrointestinal Medical Oncology Division, National Cancer Center Hospital, Tokyo, Japan.
Puccio I; Department of Cellular Pathology, University College London Hospital, London, UK.
Hikichi T; R&D Department, Cancer Precision Medicine, Inc., Kawasaki, Japan.
Yoshimura S; R&D Department, Cancer Precision Medicine, Inc., Kawasaki, Japan.
Nakagawa T; Drug Discovery and Disease Research Laboratory, Shionogi & Co., Ltd., Toyonaka, Japan.
Furukawa M; Biostatistics Department, Shionogi & Co., Ltd., Osaka, Japan.
Stoeber K; Business Development, Shionogi & Co., Ltd., London, UK.
Nagira M; Drug Discovery and Disease Research Laboratory, Shionogi & Co., Ltd., Toyonaka, Japan.
Ide N; Project Management Department, Shionogi & Co., Ltd., Osaka, Japan.
Kojima T; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
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Źródło :
Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2020 Nov; Vol. 69 (11), pp. 2247-2257. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study
MeSH Terms :
Cancer Vaccines/*therapeutic use
Esophageal Neoplasms/*drug therapy
Esophageal Neoplasms/*immunology
Lymphocytes, Tumor-Infiltrating/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Aged ; Antigens, Neoplasm/immunology ; Female ; HLA-A24 Antigen/immunology ; Humans ; Lymphocytes, Tumor-Infiltrating/drug effects ; Male ; Middle Aged ; T-Lymphocytes, Cytotoxic/drug effects ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/immunology ; Vaccines, Subunit/therapeutic use
Czasopismo naukowe
Tytuł :
Circulating β cell-specific CD8 T cells restricted by high-risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes.
Autorzy :
Yeo L; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
Pujol-Autonell I; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Baptista R; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
Eichmann M; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Kronenberg-Versteeg D; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Heck S; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.
Dolton G; Division of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
Sewell AK; Division of Infection and Immunity, School of Medicine and Systems Immunity Research Institute, Cardiff University, Cardiff, UK.
Härkönen T; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Mikk ML; Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.
Toppari J; Department of Paediatrics, University of Turku and Turku University Hospital, Turku, Finland.; Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, Turku, Finland.
Veijola R; Department of Paediatrics, PEDEGO Research Unit, Medical Research Centre, Oulu University Hospital and University of Oulu, Oulu, Finland.
Knip M; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Pediatrics, Tampere University Hospital, Tampere, Finland.; Folkhälsan Research Centre, Helsinki, Finland.
Ilonen J; Immunogenetics Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.; Clinical Microbiology, Turku University Hospital, Turku, Finland.
Peakman M; Department of Immunobiology, Faculty of Life Sciences and Medicine, King's College London, London, UK.; National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' Hospital and King's College London, London, UK.; King's Health Partners Institute of Diabetes, Endocrinology and Obesity, London, UK.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2020 Mar; Vol. 199 (3), pp. 263-277. Date of Electronic Publication: 2019 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Diabetes Mellitus, Type 1/*immunology
Histocompatibility Antigens Class I/*immunology
Insulin-Secreting Cells/*immunology
Autoimmunity/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Child ; Child, Preschool ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/metabolism ; Female ; HLA-A24 Antigen/immunology ; HLA-A24 Antigen/metabolism ; HLA-B Antigens/immunology ; HLA-B Antigens/metabolism ; Histocompatibility Antigens Class I/metabolism ; Humans ; Infant ; Insulin/immunology ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Male ; Protein Precursors/immunology ; Protein Precursors/metabolism ; Risk Factors
Czasopismo naukowe
Tytuł :
Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control.
Autorzy :
Murakoshi H; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan.
Koyanagi M; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan.
Akahoshi T; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan.
Chikata T; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan.
Kuse N; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan.
Gatanaga H; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan; AIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
Rowland-Jones SL; IRCMS, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan; Nuffield Department of Medicine, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK.
Oka S; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan; AIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan.
Takiguchi M; Center for AIDS Research, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto, Japan; Nuffield Department of Medicine, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2018 Oct; Vol. 36, pp. 103-112. Date of Electronic Publication: 2018 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
HIV Infections/*immunology
HIV Infections/*virology
HIV-1/*genetics
HIV-1/*immunology
HLA-A24 Antigen/*immunology
HLA-B35 Antigen/*immunology
Host-Pathogen Interactions/*immunology
Cytokines/metabolism ; Disease Progression ; Epitopes, T-Lymphocyte/chemistry ; HLA-A24 Antigen/chemistry ; HLA-B35 Antigen/chemistry ; Humans ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; T-Lymphocyte Subsets/virology ; Viral Load ; Virus Replication/immunology ; nef Gene Products, Human Immunodeficiency Virus/genetics
Czasopismo naukowe
Tytuł :
Identification and characterization of HLA-A24-specific XBP1, CD138 (Syndecan-1) and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma.
Autorzy :
Bae J; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Hideshima T; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Zhang GL; Boston University, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.
Zhou J; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Keskin DB; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Munshi NC; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; VA Boston Healthcare System, Boston, MA, USA.
Anderson KC; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
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Źródło :
Leukemia [Leukemia] 2018 Mar; Vol. 32 (3), pp. 752-764. Date of Electronic Publication: 2017 Nov 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
ADP-ribosyl Cyclase 1/*immunology
HLA-A24 Antigen/*immunology
Multiple Myeloma/*immunology
Peptides/*immunology
T-Cell Antigen Receptor Specificity/*immunology
T-Lymphocytes, Cytotoxic/*immunology
X-Box Binding Protein 1/*immunology
ADP-ribosyl Cyclase 1/chemistry ; ADP-ribosyl Cyclase 1/metabolism ; Amino Acid Sequence ; Biomarkers ; Cell Line, Tumor ; Cytokines/metabolism ; Cytotoxicity, Immunologic ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/metabolism ; HLA-A24 Antigen/genetics ; HLA-A24 Antigen/metabolism ; Humans ; Immunologic Memory ; Intercellular Signaling Peptides and Proteins ; Lymphocyte Activation/immunology ; Multiple Myeloma/genetics ; Multiple Myeloma/metabolism ; Peptides/chemistry ; Peptides/metabolism ; Phenotype ; Protein Binding ; T-Lymphocytes, Cytotoxic/metabolism ; X-Box Binding Protein 1/chemistry ; X-Box Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
SLC30A8 polymorphism and BMI complement HLA-A*24 as risk factors for poor graft function in islet allograft recipients.
Autorzy :
Balke EM; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium. .
Demeester S; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Lee D; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
Gillard P; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
Hilbrands R; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Van de Velde U; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Van der Auwera BJ; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Ling Z; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Roep BO; Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.; Department of Diabetes Immunology, Diabetes and Metabolism Research Institute, Beckman Research Institute at the City of Hope, Duarte, CA, USA.
Pipeleers DG; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Keymeulen B; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
Gorus FK; Diabetes Research Center, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium.
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Źródło :
Diabetologia [Diabetologia] 2018 Jul; Vol. 61 (7), pp. 1623-1632. Date of Electronic Publication: 2018 Apr 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Mass Index*
Polymorphism, Genetic*
Blood Glucose/*metabolism
Diabetes Mellitus, Type 1/*surgery
HLA-A24 Antigen/*genetics
Insulin-Secreting Cells/*transplantation
Islets of Langerhans Transplantation/*adverse effects
Zinc Transporter 8/*genetics
Allografts ; Biomarkers/blood ; Blood Glucose/drug effects ; Clinical Trials as Topic ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 1/immunology ; Female ; HLA-A24 Antigen/immunology ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Insulin-Secreting Cells/immunology ; Insulin-Secreting Cells/metabolism ; Male ; Middle Aged ; Recovery of Function ; Retrospective Studies ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
[Bioinformation analysis, eukaryotic expression and identification of β2m-linker 2-HLA A24].
Autorzy :
Gao W; Department of Immunology, College of Basic Medical Science, Chongqing Medical University, Chongqing 400016, China.
Chen S; Department of Immunology, College of Basic Medical Science, Chongqing Medical University, Chongqing 400016, China.
Xu M; Department of Immunology, College of Basic Medical Science, Chongqing Medical University, Chongqing 400016, China.
Tao K; Department of Immunology, College of Basic Medical Science, Chongqing Medical University, Chongqing 400016, China. *Corresponding author, E-mail: .
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Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2020 May; Vol. 36 (5), pp. 398-403.
Typ publikacji :
Journal Article
MeSH Terms :
Eukaryota*
HLA-A24 Antigen ; Humans ; Peptides/genetics ; T-Lymphocytes, Cytotoxic/immunology
Czasopismo naukowe
Tytuł :
HLA-A*24:388N: a novel HLA-A*24 allele identified by sequence-based typing.
Autorzy :
Wang D; BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China.; BGI-Shenzhen, Shenzhen, China.
Yang X; BGI-Shenzhen, Shenzhen, China.
Chai X; BGI-Shenzhen, Shenzhen, China.
Fang J; BGI-Shenzhen, Shenzhen, China.
Zhang X; BGI-Shenzhen, Shenzhen, China.
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Źródło :
HLA [HLA] 2017 Dec; Vol. 90 (6), pp. 364-365. Date of Electronic Publication: 2017 Oct 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
Codon, Nonsense*
Exons*
Polymorphism, Single Nucleotide*
HLA-A24 Antigen/*genetics
Asian Continental Ancestry Group ; Base Sequence ; Codon/chemistry ; Gene Expression ; Genotype ; HLA-A24 Antigen/immunology ; Hematopoietic Stem Cell Transplantation ; Histocompatibility Testing ; Humans ; Polymerase Chain Reaction ; Sequence Analysis, DNA ; Tissue Donors
Czasopismo naukowe
Tytuł :
HLA-A*24:02 is associated with metronidazole-induced cutaneous adverse drug reactions in Han Chinese individuals: A pilot case-control study with both HLA gene and T cell receptor repertoire analysis.
Autorzy :
Yang F; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Jiang M; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhang W; Fudan University Pudong Medical Center, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; The Department of Systems Biology for Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Qiao Y; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Chen SA; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Wang D; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhu H; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhang J; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Qin S; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China.
Zhu Q; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Lv Y; The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Xing Q; Children's Hospital & Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Luo X; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
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Źródło :
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Feb; Vol. 126 (2), pp. 133-143. Date of Electronic Publication: 2019 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*adverse effects
Asian Continental Ancestry Group/*genetics
Drug Eruptions/*etiology
HLA-A24 Antigen/*genetics
Metronidazole/*adverse effects
Adult ; Aged ; Alleles ; Anti-Infective Agents/administration & dosage ; Case-Control Studies ; Drug Eruptions/genetics ; Female ; HLA-B Antigens/genetics ; Humans ; Male ; Metronidazole/administration & dosage ; Middle Aged ; Molecular Docking Simulation ; Pilot Projects ; Receptors, Antigen, T-Cell/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Identification of HLA-A*24:02:78 by next-generation sequencing in a Chinese Han individual.
Autorzy :
Gao SQ; Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.
Hong WX; Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.
Deng ZH; Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.
Quan ZR; Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.
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Źródło :
HLA [HLA] 2019 Dec; Vol. 94 (6), pp. 519-521. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Donors*
Asian Continental Ancestry Group/*genetics
HLA-A24 Antigen/*genetics
Alleles ; Asian Continental Ancestry Group/ethnology ; China/ethnology ; Exons ; High-Throughput Nucleotide Sequencing ; Humans
Czasopismo naukowe
Tytuł :
Characterization of seven new HLA alleles, A*24:14:01:04, A*29:02:01:07, C*06:02:01:37, C*07:830, C*16:162, C*16:01:01:07 and DQA1*01:02:05.
Autorzy :
Planelles D; Histocompatibilidad, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Balas A; Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.
Rodríguez-Cebriá M; Histocompatibilidad, Centro de Transfusión de la Comunidad Valenciana, Valencia, Spain.
Moreno-Hidalgo MA; Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.
Vicario JL; Histocompatibilidad, Centro de Transfusión de la Comunidad de Madrid, Madrid, Spain.
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Źródło :
HLA [HLA] 2019 Dec; Vol. 94 (6), pp. 521-522. Date of Electronic Publication: 2019 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
HLA-A Antigens/*genetics
HLA-A24 Antigen/*genetics
HLA-C Antigens/*genetics
HLA-DQ alpha-Chains/*genetics
Alleles ; Cohort Studies ; Gene Frequency ; Genetics, Population ; Haplotypes ; High-Throughput Nucleotide Sequencing ; Humans ; Polymorphism, Genetic ; Spain/epidemiology
Czasopismo naukowe
Tytuł :
Detection of a novel allele, HLA-A*24:198, by sequence-based typing in a Chinese individual.
Autorzy :
Wang K; Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.; Department of Dermatology, Shijingshan Teaching Hospital of Capital Medical University, Beijing Shijingshan Hospital, Beijing, China.
Li XF; HLA Laboratory, Liaoning Blood Center, Shenyang, China.; Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.; Key Laboratory of Blood Safety Research of Shenyang, Shenyang, China.
Zhang X; HLA Laboratory, Liaoning Blood Center, Shenyang, China.; Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.; Key Laboratory of Blood Safety Research of Shenyang, Shenyang, China.
Lin FQ; HLA Laboratory, Liaoning Blood Center, Shenyang, China.; Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.; Key Laboratory of Blood Safety Research of Shenyang, Shenyang, China.
Li JP; HLA Laboratory, Liaoning Blood Center, Shenyang, China.; Key Laboratory of Blood Safety Research of Liaoning, Shenyang, China.; Key Laboratory of Blood Safety Research of Shenyang, Shenyang, China.; Shenyang Research Center for Cell Application, Shenyang, China.
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Źródło :
HLA [HLA] 2017 Nov; Vol. 90 (5), pp. 306-307. Date of Electronic Publication: 2017 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
Asian Continental Ancestry Group/*genetics
HLA-A24 Antigen/*genetics
Histocompatibility Testing/*methods
Amino Acid Sequence ; Base Sequence ; Exons/genetics ; HLA-A24 Antigen/chemistry ; Heterozygote ; Humans ; Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax 301-309 -Specific Cytotoxic T Cells in HLA-A24:02-Positive Asymptomatic Carriers and Adult T-Cell Leukemia/Lymphoma Patients.
Autorzy :
Ishihara Y; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Tanaka Y; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Kobayashi S; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Kawamura K; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Nakasone H; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Gomyo A; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Hayakawa J; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Tamaki M; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Akahoshi Y; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Harada N; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Kusuda M; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Kameda K; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Ugai T; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Wada H; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Sakamoto K; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Sato M; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Terasako-Saito K; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Kikuchi M; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Kimura SI; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Tanihara A; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Kako S; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Uchimaru K; Laboratory of Tumor Cell Biology, Department of Medical Genome Science, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan.
Kanda Y; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan .
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Źródło :
Journal of virology [J Virol] 2017 Sep 12; Vol. 91 (19). Date of Electronic Publication: 2017 Sep 12 (Print Publication: 2017).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Products, tax/*immunology
HLA-A24 Antigen/*immunology
Human T-lymphotropic virus 1/*immunology
Leukemia-Lymphoma, Adult T-Cell/*immunology
Receptors, Antigen, T-Cell/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Amino Acid Sequence/genetics ; Antigens, CD7/metabolism ; Cell Adhesion Molecule-1 ; Cell Adhesion Molecules/metabolism ; Cells, Cultured ; Gene Products, tax/genetics ; HLA-A24 Antigen/genetics ; HTLV-I Infections/pathology ; HTLV-I Infections/virology ; Human T-lymphotropic virus 1/genetics ; Humans ; Immunoglobulins/metabolism ; Immunologic Memory/immunology ; Leukemia-Lymphoma, Adult T-Cell/genetics ; Receptors, Antigen, T-Cell/genetics
Czasopismo naukowe
Tytuł :
Distinct Polymorphisms in HLA Class I Molecules Govern Their Susceptibility to Peptide Editing by TAPBPR.
Autorzy :
Ilca FT; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
Drexhage LZ; Faculty of Biology, University of Freiburg, Schaenzlestrasse 1, 79104 Freiburg, Germany.
Brewin G; Tissue Typing Laboratory, Box 209, Level 6 ATC, Cambridge University Hospitals, NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
Peacock S; Tissue Typing Laboratory, Box 209, Level 6 ATC, Cambridge University Hospitals, NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK.
Boyle LH; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2019 Nov 05; Vol. 29 (6), pp. 1621-1632.e3.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
HLA-A Antigens/*chemistry
HLA-A Antigens/*metabolism
Histocompatibility Antigens Class I/*chemistry
Histocompatibility Antigens Class I/*metabolism
Immunoglobulins/*metabolism
Membrane Proteins/*metabolism
Antigen Presentation ; HEK293 Cells ; HLA-A2 Antigen/chemistry ; HLA-A2 Antigen/metabolism ; HLA-A24 Antigen/chemistry ; HLA-A24 Antigen/metabolism ; HLA-B Antigens/genetics ; HLA-B Antigens/metabolism ; HLA-C Antigens/metabolism ; HeLa Cells ; Histocompatibility Antigens Class I/genetics ; Humans ; Immunoglobulin Allotypes ; Immunoglobulins/genetics ; Membrane Proteins/genetics ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Molecular Chaperones/chemistry ; Molecular Chaperones/metabolism ; Peptides/chemistry ; Peptides/metabolism ; Polymorphism, Genetic ; Protein Binding ; Protein Domains/genetics
Czasopismo naukowe
Tytuł :
Identification of the new HLA-A*24:02:131 allele in a Brazilian candidate donor for bone marrow donation.
Autorzy :
Vianna R; Laboratório de Histocompatibilidade e Criopreservação, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Secco D; Laboratório de Histocompatibilidade e Criopreservação, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Hanhoerster L; Laboratório de Histocompatibilidade e Criopreservação, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Porto LC; Laboratório de Histocompatibilidade e Criopreservação, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
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Źródło :
HLA [HLA] 2019 Nov; Vol. 94 (5), pp. 440-441. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Polymorphism, Single Nucleotide*
Tissue Donors*
Bone Marrow/*immunology
Bone Marrow Transplantation/*methods
HLA-A24 Antigen/*genetics
HLA-A24 Antigen/*immunology
Histocompatibility Testing/*methods
Brazil ; High-Throughput Nucleotide Sequencing ; Humans
Czasopismo naukowe
Tytuł :
Multiple therapeutic peptide vaccines for patients with advanced gastric cancer.
Autorzy :
Fujiwara Y; Department of Surgery, Division of Surgical Oncology, Faculty of Medicine, Tottori University, Yonago 683-8504, Japan.
Okada K; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Omori T; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Sugimura K; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Miyata H; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Ohue M; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Kobayashi S; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Takahashi H; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Nakano H; Department of Pharmacy, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Mochizuki C; Department of Pharmacy, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Shimizu K; Department of Pharmacy, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Yano M; Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan.
Nakamura Y; Center for Personalized Therapeutics, The University of Chicago, Chicago, IL 60637, USA.
Mori M; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
Doki Y; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan.
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Źródło :
International journal of oncology [Int J Oncol] 2017 May; Vol. 50 (5), pp. 1655-1662. Date of Electronic Publication: 2017 Apr 06.
Typ publikacji :
Clinical Trial, Phase II; Journal Article
MeSH Terms :
Cancer Vaccines/*administration & dosage
HLA-A24 Antigen/*immunology
Stomach Neoplasms/*therapy
Vaccines, Subunit/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Angiogenesis Inhibitors/adverse effects ; Angiogenesis Inhibitors/immunology ; Angiogenesis Inhibitors/therapeutic use ; Cancer Vaccines/immunology ; Disease-Free Survival ; Female ; Forkhead Box Protein M1/immunology ; Forkhead Box Protein M1/therapeutic use ; GTPase-Activating Proteins/immunology ; GTPase-Activating Proteins/therapeutic use ; HLA-A24 Antigen/therapeutic use ; Humans ; Kaplan-Meier Estimate ; Kinesin/immunology ; Kinesin/therapeutic use ; Male ; Middle Aged ; Neoplasm Proteins/immunology ; Neoplasm Proteins/therapeutic use ; Neoplasm Staging ; Stomach Neoplasms/immunology ; Stomach Neoplasms/pathology ; Treatment Outcome ; Vaccines, Subunit/adverse effects ; Vaccines, Subunit/immunology ; Vascular Endothelial Growth Factor Receptor-1/immunology ; Vascular Endothelial Growth Factor Receptor-1/therapeutic use
Czasopismo naukowe
Tytuł :
The full length genomic sequence of a novel HLA-A*24 allele, HLA-A*24:353, identified in a patient with hepatitis B infection.
Autorzy :
Gao SQ; Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Xu YP; Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
He LM; Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Zhang H; Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
Yang AL; Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, China.
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Źródło :
HLA [HLA] 2017 May; Vol. 89 (5), pp. 304-305. Date of Electronic Publication: 2017 Mar 12.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
Exons*
Polymorphism, Single Nucleotide*
HLA-A24 Antigen/*genetics
T-Lymphocytes, Cytotoxic/*immunology
Amino Acid Substitution ; Asian Continental Ancestry Group ; Base Sequence ; Cloning, Molecular ; Codon/chemistry ; Gene Expression ; Genotype ; HLA-A24 Antigen/immunology ; Hepatitis B/immunology ; Hepatitis B/virology ; Histocompatibility Testing ; Humans ; Polymerase Chain Reaction ; Sequence Alignment ; Sequence Analysis, DNA ; T-Lymphocytes, Cytotoxic/virology
Czasopismo naukowe

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