- Tytuł :
- TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice.
- Autorzy :
- Źródło :
- Journal of leukocyte biology [J Leukoc Biol] 2020 Jun; Vol. 107 (6), pp. 1069-1079. Date of Electronic Publication: 2020 Feb 05.
- Typ publikacji :
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms :
-
HLA-A24 Antigen /*genetics
Receptors,Antigen , T-Cell, gamma-delta/*genetics
Soft Tissue Neoplasms/*prevention & control
T-Lymphocytes, Regulatory/*immunology
Adoptive Transfer ; Animals ; Cell Engineering ; Gene Expression ; Graft vs Host Disease/genetics ; Graft vs Host Disease/immunology ; Graft vs Host Disease/prevention & control ;HLA-A24 Antigen /immunology ; Humans ; Immunotherapy/methods ; K562 Cells ; Male ; Mice ; Mice, Transgenic ; Receptors,Antigen , T-Cell, gamma-delta/immunology ; Signal Transduction ; Soft Tissue Neoplasms/genetics ; Soft Tissue Neoplasms/immunology ; Soft Tissue Neoplasms/pathology ; T-Lymphocytes, Regulatory/pathology ; T-Lymphocytes, Regulatory/transplantation ; Transduction, Genetic ; Whole-Body Irradiation -
Czasopismo naukowe