Temat: "HSP70 Heat-Shock Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca -Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
Autorzy:: Li Y; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Li HY; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Shao J; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Zhu L; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Xie TH; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Cai J; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Wang W; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Cai MX; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Wang ZL; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Yao Y; Department of Ophthalmology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Wei TT; Center of Clinical Research, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Nov 29; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Diabetic Retinopathy*/metabolism
Diabetic Retinopathy*/pathology
Mitochondria*/metabolism
HSP70 Heat-Shock Proteins*/metabolism
Mitochondrial Proteins*/metabolism
Animals ; Humans ; Rats ; Calcium/metabolism ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Stress ; Endothelial Cells/metabolism

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Skocz do pozycji: 2.

Tytuł:: The Role of p53 Protein in the Realization of the Exogenous Heat Shock Protein 70 Anti-Apoptotic Effect during Axotomy.
Autorzy:: Demyanenko SV; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Pitinova MA; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Dzreyan VA; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Kalyuzhnaya YN; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Eid MA; Laboratory of Molecular Neurobiology, Academy of Biology and Biotechnology, Southern Federal University, 344090 Rostov-on-Don, Russia.
Abramov AY; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, Queen Square, London WC1N 3BG, UK.
Evgen'ev MB; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Garbuz DG; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Dec 29; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Axotomy*
Astacoidea/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Tumor Suppressor Protein p53/*metabolism
Animals ; Down-Regulation ; E2F1 Transcription Factor/metabolism ; HSP70 Heat-Shock Proteins/isolation & purification ; Humans ; Mechanoreceptors/metabolism ; Mercaptoethylamines/pharmacology ; Necrosis ; Neuroglia/metabolism ; Neurons/metabolism ; Proto-Oncogene Proteins c-myc/metabolism ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism

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Skocz do pozycji: 3.

Tytuł:: Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer.
Autorzy:: Yurasakpong L; Department of Anatomy, Faculty of Science, Mahidol University, Rama VI Road, Ratchathewi, Bangkok 10400, Thailand.
Nantasenamat C; Center of Data Mining and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
Nobsathian S; Nakornsawan Campus, Mahidol University, Nakonsawan 60130, Thailand.
Chaithirayanon K; Department of Anatomy, Faculty of Science, Mahidol University, Rama VI Road, Ratchathewi, Bangkok 10400, Thailand.
Apisawetakan S; Department of Anatomy, Faculty of Medicine, Srinakharinwirot University, Wattana, Bangkok 10110, Thailand.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 22; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Apoptosis/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
HSP70 Heat-Shock Proteins/*genetics
Pentacyclic Triterpenes/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Colorectal Neoplasms ; Dose-Response Relationship, Drug ; Flow Cytometry ; HSP70 Heat-Shock Proteins/chemistry ; HSP70 Heat-Shock Proteins/metabolism ; Humans ; Molecular Conformation ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Pentacyclic Triterpenes/chemistry ; Structure-Activity Relationship ; Betulinic Acid

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Skocz do pozycji: 4.

Tytuł:: Heat shock protein 70 attenuates hypoxia‑induced apoptosis of pulmonary microvascular endothelial cells isolated from neonatal rats.
Autorzy:: Cao J; Department of Echocardiography, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Yang L; Department of Echocardiography, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Wang L; Department of Neonatology, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Zhao Q; School of Pediatrics, Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Wu D; School of Pediatrics, Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Li M; Department of Neonatology, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.
Mu Y; Department of Echocardiography, The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uyghur Autonomous Region 830054, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Oct; Vol. 24 (4). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/genetics
Endothelial Cells*/cytology
Endothelial Cells*/metabolism
HSP70 Heat-Shock Proteins*/genetics
HSP70 Heat-Shock Proteins*/metabolism
Hypertension, Pulmonary*/metabolism
Microvessels*/cytology
Microvessels*/metabolism
Animals ; Animals, Newborn ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Hypoxia ; Down-Regulation ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mitochondria/metabolism ; Primary Cell Culture ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats, Sprague-Dawley ; Signal Transduction/genetics ; Up-Regulation ; Rats

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Skocz do pozycji: 5.

Tytuł:: Rapid and simple screening of the apoptotic compounds based on Hsp70 inhibition using luciferase as an intracellular reporter.
Autorzy:: Jahangirizadeh Z; Department of Biology, Faculty of Science, University of Guilan, P.O. Box 41335-1914, Rasht, Iran.
Ghafouri H; Department of Biology, Faculty of Science, University of Guilan, P.O. Box 41335-1914, Rasht, Iran. .
Sajedi RH; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.
Sariri R; Department of Biology, Faculty of Science, University of Guilan, P.O. Box 41335-1914, Rasht, Iran.
Hossienkhani S; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2020 Jan; Vol. 412 (1), pp. 149-158. Date of Electronic Publication: 2020 Jan 02.
Typ publikacji:: Journal Article
MeSH Terms:: Genes, Reporter*
Apoptosis/*drug effects
HSP70 Heat-Shock Proteins/*antagonists & inhibitors
Luciferases, Firefly/*genetics
Dactinomycin/pharmacology ; Dose-Response Relationship, Drug ; Doxorubicin/pharmacology ; Drug Evaluation, Preclinical ; Escherichia coli/genetics ; HSP70 Heat-Shock Proteins/genetics

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Skocz do pozycji: 6.

Tytuł:: Different responses of apoptotic, inflammatory and heat shock protein gene expression to a single bout of high-intensity interval exercise between physically active and inactive men.
Autorzy:: Vardar SA; Department of Physiology, Medical Faculty, Trakya University, Edirne, Turkey.
Doğanlar ZB; Department of Medical Biology, Medical Faculty, Trakya University, Edirne, Turkey.
Kaya O; Department of Physiology, Medical Faculty, Trakya University, Edirne, Turkey.
Tayfur P; Department of Physiology, Health Science Institute, Trakya University, Edirne, Turkey.
Sut N; Department of Biostatistics, Medical, Faculty, Trakya University, Edirne, Turkey.
Doğanlar O; Department of Medical Biology, Medical Faculty, Trakya University, Edirne, Turkey.; Pokaż więcej
Źródło:: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme [Appl Physiol Nutr Metab] 2021 Jul; Vol. 46 (7), pp. 743-752. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji:: Journal Article
MeSH Terms:: Sedentary Behavior*
Apoptosis/*physiology
Heat-Shock Proteins/*genetics
High-Intensity Interval Training/*methods
Inflammation/*blood
Muscle, Skeletal/*cytology
Muscle, Skeletal/*physiology
Physical Fitness/*physiology
Adaptation, Physiological ; Adolescent ; Adult ; Biomarkers/blood ; Chaperonin 60/blood ; Gene Expression ; HSP70 Heat-Shock Proteins/blood ; Humans ; Interleukin-6/blood ; Male ; Mitochondrial Proteins/blood ; RNA, Messenger/blood ; Tumor Necrosis Factor-alpha/blood ; Young Adult

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Skocz do pozycji: 7.

Tytuł:: Inhibition of HSF1 and SAFB Granule Formation Enhances Apoptosis Induced by Heat Stress.
Autorzy:: Watanabe K; Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 7008530, Japan.
Ohtsuki T; Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama 7008530, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 07; Vol. 22 (9). Date of Electronic Publication: 2021 May 07.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/drug effects
Heat-Shock Response*/drug effects
Heat Shock Transcription Factors/*antagonists & inhibitors
Matrix Attachment Region Binding Proteins/*metabolism
Nuclear Matrix-Associated Proteins/*metabolism
Receptors, Estrogen/*metabolism
Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cytoplasmic Granules/drug effects ; Cytoplasmic Granules/metabolism ; Gene Knockdown Techniques ; Glycols/pharmacology ; HSP27 Heat-Shock Proteins/metabolism ; HSP70 Heat-Shock Proteins/metabolism ; HeLa Cells ; Heat Shock Transcription Factors/metabolism ; Humans ; Models, Biological ; TRPV Cation Channels/antagonists & inhibitors ; TRPV Cation Channels/metabolism ; Temperature ; Up-Regulation/drug effects

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Skocz do pozycji: 8.

Tytuł:: Ischaemic postconditioning reduces apoptosis in experimental jejunal ischaemia in horses.
Autorzy:: Verhaar N; Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany. .
de Buhr N; Department of Biochemistry, University of Veterinary Medicine Hannover, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, Hannover, Germany.
von Köckritz-Blickwede M; Department of Biochemistry, University of Veterinary Medicine Hannover, Hannover, Germany.; Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, Hannover, Germany.
Hewicker-Trautwein M; Institute of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
Pfarrer C; Institute for Anatomy, University of Veterinary Medicine Hannover, Hannover, Germany.
Mazzuoli-Weber G; Institute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Hannover, Germany.
Schulte H; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Kästner S; Clinic for Horses, University of Veterinary Medicine Hannover, Hannover, Germany.; Small Animal Clinic, University of Veterinary Medicine Hannover, Hannover, Germany.; Pokaż więcej
Źródło:: BMC veterinary research [BMC Vet Res] 2021 Apr 26; Vol. 17 (1), pp. 175. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:: Journal Article; Randomized Controlled Trial, Veterinary
MeSH Terms:: Apoptosis*
Ischemic Postconditioning/*veterinary
Jejunum/*blood supply
Reperfusion Injury/*veterinary
Animals ; HSP70 Heat-Shock Proteins/metabolism ; Horses ; Intestinal Mucosa/metabolism ; Ischemic Postconditioning/methods ; Jejunum/pathology ; Lactic Acid/blood ; Malondialdehyde/metabolism ; Reperfusion Injury/therapy ; Superoxide Dismutase/metabolism

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Skocz do pozycji: 9.

Tytuł:: Bag-1L Protects against Cell Apoptosis in an In Vitro Model of Lung Ischemia-Reperfusion Injury through the C-Terminal "Bag" Domain.
Autorzy:: Lv JL; Department of Respiratory Medicine, Shandong Second Provincial General Hospital, Jinan, 250000 Shandong, China.; Department of Intensive Care Unit, Affiliated Qingdao Municipal Hospital of Qingdao University, Qingdao, 266071 Shandong, China.
Shi LN; Zibo Traditional Chinese Medicine Hospital, Zibo, 255200 Shandong, China.
Zhai CY; Department of Respiratory Medicine, The First Hospital of Zibo, Zibo, 255200 Shandong, China.
Wang GJ; Affiliated Hospital of Zibo Vocational Institute, Zibo, 255314 Shandong, China.
Qu Y; Department of Intensive Care Unit, Affiliated Qingdao Municipal Hospital of Qingdao University, Qingdao, 266071 Shandong, China.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Mar 17; Vol. 2021, pp. 8822807. Date of Electronic Publication: 2021 Mar 17 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
DNA-Binding Proteins/*pharmacology
Lung/*metabolism
Protective Agents/*pharmacology
Reperfusion Injury/*drug therapy
Transcription Factors/*pharmacology
A549 Cells ; Adenoviridae ; Cell Cycle ; Cell Survival ; DNA-Binding Proteins/genetics ; Gene Expression ; HSP70 Heat-Shock Proteins/metabolism ; Humans ; Hypoxia ; Protein Isoforms/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Transcription Factors/genetics

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Skocz do pozycji: 10.

Tytuł:: Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3.
Autorzy:: Sverchinsky DV; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Nikotina AD; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Komarova EY; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Mikhaylova ER; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Aksenov ND; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Lazarev VF; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Mitkevich VA; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova, Moscow 119991, Russia. .
Suezov R; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Druzhilovskiy DS; Institute of Biomedical Chemistry, Pogodinskaya str., 10, bldg. 8, Moscow 119121, Russia. .
Poroikov VV; Institute of Biomedical Chemistry, Pogodinskaya str., 10, bldg. 8, Moscow 119121, Russia. .
Margulis BA; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .
Guzhova IV; Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, St., Petersburg 194064, Russia. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Aug 25; Vol. 19 (9). Date of Electronic Publication: 2018 Aug 25.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Caspase 3/*metabolism
Etoposide/*pharmacology
HSP70 Heat-Shock Proteins/*metabolism
Neoplasms/*metabolism
Apoptosis/genetics ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; HSP70 Heat-Shock Proteins/genetics ; Humans ; Protein Binding

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Skocz do pozycji: 11.

Tytuł:: Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression.
Autorzy:: Zhang MH; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Zhou XM; Department of Neurosurgery, Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.
Cui JZ; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Wang KJ; Department of Neurosurgery, Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.
Feng Y; Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Zhang HA; Department of Neurosurgery, Tangshan Workers' Hospital, Tangshan, Hebei 063000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Jun; Vol. 17 (6), pp. 8079-8086. Date of Electronic Publication: 2018 Apr 19.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*genetics
Brain Injuries, Traumatic/*genetics
Brain Injuries, Traumatic/*metabolism
Dexmedetomidine/*pharmacology
HSP70 Heat-Shock Proteins/*genetics
Neuroprotective Agents/*pharmacology
Animals ; Apoptosis/drug effects ; Biomarkers ; Brain Edema/etiology ; Brain Injuries, Traumatic/complications ; HSP70 Heat-Shock Proteins/metabolism ; Hippocampus/metabolism ; Immunohistochemistry ; Male ; Neurons/metabolism ; Rats ; Spatial Learning

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Skocz do pozycji: 12.

Tytuł:: Histological study of gonadal tissues of adult Artemia salina (Linnaeus 1758) and immunohistochemistry by Caspase 3 and HSP70 to detect specific apoptosis markers on gonadal tissues after exposure to TBTCl.
Autorzy:: Abushaala NM; Zoology Department, Faculty of Science, University of Tripoli, Tripoli, Libya.
Elfituri AM; Marine Biology Research Centre, Tajoura, Libya.
Zulkifli SZ; Department of Biology, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.; Pokaż więcej
Źródło:: Open veterinary journal [Open Vet J] 2021 Jan-Mar; Vol. 11 (1), pp. 112-120. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Artemia/*drug effects
Arthropod Proteins/*metabolism
Trialkyltin Compounds/*adverse effects
Water Pollutants, Chemical/*adverse effects
Animals ; Artemia/metabolism ; Biomarkers/metabolism ; Caspase 3/metabolism ; Female ; HSP70 Heat-Shock Proteins/metabolism ; Immunohistochemistry ; Male ; Ovary/drug effects ; Ovary/metabolism ; Testis/drug effects ; Testis/metabolism

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Skocz do pozycji: 13.

Tytuł:: Effects of MDMA (ecstasy) on apoptosis and heat shock protein (HSP70) expression in adult rat testis.
Autorzy:: Mobaraki F; a Department of Anatomy and Cell Biology, School of Medicine , Mashhad University of Medical Sciences , Mashhad , Iran.
Seghatoleslam M; a Department of Anatomy and Cell Biology, School of Medicine , Mashhad University of Medical Sciences , Mashhad , Iran.; b Microanatomy Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.
Fazel A; a Department of Anatomy and Cell Biology, School of Medicine , Mashhad University of Medical Sciences , Mashhad , Iran.; b Microanatomy Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.
Ebrahimzadeh-Bideskan A; a Department of Anatomy and Cell Biology, School of Medicine , Mashhad University of Medical Sciences , Mashhad , Iran.; b Microanatomy Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.; Pokaż więcej
Źródło:: Toxicology mechanisms and methods [Toxicol Mech Methods] 2018 Mar; Vol. 28 (3), pp. 219-229. Date of Electronic Publication: 2017 Nov 05.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Gene Expression Regulation, Developmental/*drug effects
HSP70 Heat-Shock Proteins/*metabolism
Hallucinogens/*toxicity
N-Methyl-3,4-methylenedioxyamphetamine/*toxicity
Substance-Related Disorders/*etiology
Testis/*drug effects
Animals ; Body Temperature Regulation/drug effects ; Dose-Response Relationship, Drug ; HSP70 Heat-Shock Proteins/genetics ; Hallucinogens/administration & dosage ; Immunohistochemistry ; In Situ Nick-End Labeling ; Injections, Intraperitoneal ; Leydig Cells/drug effects ; Leydig Cells/metabolism ; Leydig Cells/pathology ; Male ; N-Methyl-3,4-methylenedioxyamphetamine/administration & dosage ; Organ Size/drug effects ; Random Allocation ; Rats, Wistar ; Seminiferous Epithelium/drug effects ; Seminiferous Epithelium/metabolism ; Seminiferous Epithelium/pathology ; Substance-Related Disorders/metabolism ; Substance-Related Disorders/pathology ; Substance-Related Disorders/physiopathology ; Testis/metabolism ; Testis/pathology ; Weight Loss/drug effects

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Skocz do pozycji: 14.

Tytuł:: SIRT1 attenuates endoplasmic reticulum stress and apoptosis in rat models of COPD.
Autorzy:: Zhang L; Department of Respiratory Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Luo B; Department of Pulmonary and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Ting Y; Department of Emergency Medicine and Difficult Diseases Institute, Second Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
He S; Department of Respiratory Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Xie L; Department of Respiratory Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Sun S; Department of Respiratory Medicine, Third Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.; Pokaż więcej
Źródło:: Growth factors (Chur, Switzerland) [Growth Factors] 2020 Feb; Vol. 38 (2), pp. 94-104. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Endoplasmic Reticulum Stress*
Pulmonary Disease, Chronic Obstructive/*metabolism
Sirtuin 1/*metabolism
Animals ; Antioxidants/pharmacology ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; Lipopolysaccharides/toxicity ; Lung/drug effects ; Lung/metabolism ; Male ; Pulmonary Disease, Chronic Obstructive/etiology ; Rats ; Rats, Sprague-Dawley ; Resveratrol/pharmacology ; Sirtuin 1/genetics ; Tobacco Smoke Pollution/adverse effects

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Skocz do pozycji: 15.

Tytuł:: Hericium Erinaceus Prevents DEHP-Induced Mitochondrial Dysfunction and Apoptosis in PC12 Cells.
Autorzy:: Amara I; Laboratory for Research on Biologically Compatible Compounds, Faculty of Dental Medicine, University of Monastir, Rue Avicenne, Monastir 5019, Tunisia.; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.
Scuto M; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.
Zappalà A; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.
Ontario ML; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.
Petralia A; Department of Medical and Surgery Sciences, University of Catania, 95125, Via Santa Sofia, 78, 95123 Catania, Italy.
Abid-Essefi S; Laboratory for Research on Biologically Compatible Compounds, Faculty of Dental Medicine, University of Monastir, Rue Avicenne, Monastir 5019, Tunisia.
Maiolino L; Department of Medical and Surgery Sciences, University of Catania, 95125, Via Santa Sofia, 78, 95123 Catania, Italy.
Signorile A; Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, Piazza G. Cesare, 11, 70124 Bari, Italy.
Trovato Salinaro A; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.
Calabrese V; Department of Biomedical and Biotechnological Sciences, University of Catania, Torre Biologica, Via Santa Sofia n. 97, 95125 Catania, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Mar 20; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 20.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/drug effects
Diethylhexyl Phthalate/*toxicity
Hericium/*chemistry
Mitochondria/*pathology
Plant Extracts/*pharmacology
Animals ; Caspase 3/metabolism ; Electron Transport Chain Complex Proteins/metabolism ; HSP70 Heat-Shock Proteins/metabolism ; Heme Oxygenase-1/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; NF-E2-Related Factor 2/metabolism ; PC12 Cells ; Rats ; Reactive Oxygen Species/metabolism ; Sirtuin 1/metabolism ; Thioredoxins/metabolism ; Tumor Suppressor Protein p53/metabolism ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 16.

Tytuł:: Hsp90 Relieves Heat Stress-Induced Damage in Mouse Kidneys: Involvement of Antiapoptotic PKM2-AKT and Autophagic HIF-1α Signaling.
Autorzy:: Chen B; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Yang B; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Zhu J; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Wu J; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Sha J; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Sun J; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Bao E; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Zhang X; Department of Basic Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Feb 28; Vol. 21 (5). Date of Electronic Publication: 2020 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Autophagy*
Heat-Shock Response*
HSP90 Heat-Shock Proteins/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Kidney/*pathology
Proto-Oncogene Proteins c-akt/*metabolism
Pyruvate Kinase/*metabolism
Animals ; Antioxidants/metabolism ; Cell Survival ; HSP70 Heat-Shock Proteins/metabolism ; Kidney/metabolism ; Male ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Mitochondrial Proteins/metabolism ; Models, Biological ; Oxidation-Reduction ; Phosphorylation ; Signal Transduction

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Skocz do pozycji: 17.

Tytuł:: A 12-mer Peptide of Tag7 (PGLYRP1) Forms a Cytotoxic Complex with Hsp70 and Inhibits TNF-Alpha Induced Cell Death.
Autorzy:: Romanova EA; Laboratory of Molecular immunogenetics of cancer, Institute of gene biology RAS, Vavilova 34/5, 111394 Moscow, Russia.
Sharapova TN; Laboratory of Molecular immunogenetics of cancer, Institute of gene biology RAS, Vavilova 34/5, 111394 Moscow, Russia.
Telegin GB; Branch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Prospect Nauki 6, 142290 Pushchino, Russia.
Minakov AN; Branch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Prospect Nauki 6, 142290 Pushchino, Russia.
Chernov AS; Branch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Prospect Nauki 6, 142290 Pushchino, Russia.
Ivanova OK; Laboratory of Molecular immunogenetics of cancer, Institute of gene biology RAS, Vavilova 34/5, 111394 Moscow, Russia.
Bychkov ML; Laboratory of bioengineering of neuromodulators and neuroreceptors, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Miklucho-Maklaya str., 16/10, 117997 Moscow, Russia.
Sashchenko LP; Laboratory of Molecular immunogenetics of cancer, Institute of gene biology RAS, Vavilova 34/5, 111394 Moscow, Russia.
Yashin DV; Laboratory of Molecular immunogenetics of cancer, Institute of gene biology RAS, Vavilova 34/5, 111394 Moscow, Russia.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Feb 20; Vol. 9 (2). Date of Electronic Publication: 2020 Feb 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Inflammatory Agents/*metabolism
Anti-Inflammatory Agents/*pharmacology
Apoptosis/*drug effects
Cytokines/*chemistry
HSP70 Heat-Shock Proteins/*metabolism
Peptides/*metabolism
Peptides/*pharmacology
Tumor Necrosis Factor-alpha/*antagonists & inhibitors
Animals ; Anti-Inflammatory Agents/therapeutic use ; Arthritis, Rheumatoid/chemically induced ; Arthritis, Rheumatoid/drug therapy ; Cytokines/immunology ; Disease Models, Animal ; Female ; Fibroblasts/metabolism ; Freund's Adjuvant/adverse effects ; HEK293 Cells ; Humans ; Immunity, Innate ; Mice ; Mice, Inbred ICR ; Necroptosis/drug effects ; Peptides/therapeutic use ; Protein Binding ; Receptors, Tumor Necrosis Factor, Type I/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/immunology ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 18.

Tytuł:: Alpha-Lipoic Acid Protects Cardiomyocytes against Heat Stroke-Induced Apoptosis and Inflammatory Responses Associated with the Induction of Hsp70 and Activation of Autophagy.
Autorzy:: Shen HH; Department and Institute of Pharmacology, National Defense Medical Center, Taipei, Taiwan.; Department of Pharmacy Practice, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Tseng YS; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Kuo NC; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Kung CW; Department of Nursing, Tzu Chi University of Science and Technology, Hualien, Taiwan.
Amin S; Department of Pharmacology, New York Medical College, New York, USA.
Lam KK; Department of Anesthesiology, Catholic Mercy Hospital, Hsinchu, Taiwan.; Department of Pharmacology, Taipei Medical University, Taipei, Taiwan.
Lee YM; Department and Institute of Pharmacology, National Defense Medical Center, Taipei, Taiwan.; Pokaż więcej
Źródło:: Mediators of inflammation [Mediators Inflamm] 2019 Dec 03; Vol. 2019, pp. 8187529. Date of Electronic Publication: 2019 Dec 03 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Autophagy/*drug effects
Heat Stroke/*drug therapy
Heat Stroke/*pathology
Inflammation/*drug therapy
Myocytes, Cardiac/*cytology
Myocytes, Cardiac/*drug effects
Thioctic Acid/*therapeutic use
Animals ; Autophagy/physiology ; HSP70 Heat-Shock Proteins/metabolism ; Heat Stroke/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Male ; NF-kappa B/metabolism ; Rats ; Rats, Wistar ; Superoxides/metabolism ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 19.

Tytuł:: PCDHGB7 Increases Chemosensitivity to Carboplatin by Inhibiting HSPA9 via Inducing Apoptosis in Breast Cancer.
Autorzy:: Hou S; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.
Shan M; Department of BC Surgery, Harbin Medical University Cancer Hospital, Harbin, China.
Gao C; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.
Feng X; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.
Yang Y; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.
Zhang R; Shuwen Biotech Co. Ltd., Deqing, China.
He Y; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.
Zhang G; Department of BC Surgery, Harbin Medical University Cancer Hospital, Harbin, China.
Zhang L; Department of Pathology, Basic Medical Science College, Harbin Medical University, Harbin, China.; Pokaż więcej
Źródło:: Disease markers [Dis Markers] 2019 Jul 08; Vol. 2019, pp. 6131548. Date of Electronic Publication: 2019 Jul 08 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Drug Resistance, Neoplasm*
Apoptosis/*drug effects
Breast Neoplasms/*drug therapy
Cadherins/*metabolism
Carboplatin/*pharmacology
Gene Expression Regulation, Neoplastic/*drug effects
HSP70 Heat-Shock Proteins/*antagonists & inhibitors
Mitochondrial Proteins/*antagonists & inhibitors
Antineoplastic Agents/pharmacology ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cadherins/genetics ; Cell Proliferation/drug effects ; Female ; Humans ; Tumor Cells, Cultured

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Skocz do pozycji: 20.

Tytuł:: Effects of dihydroartemisinin on HSP70 expression in human prostate cancer PC-3 cells.
Autorzy:: Kong J; Department of Oncology, Affiliated Hospital of Jining Medical University, Jining, China.
Li SS; Department of Oncology, Affiliated Hospital of Jining Medical University, Jining, China.
Ma Q; Department of Oncology, Affiliated Hospital of Jining Medical University, Jining, China.
Liu L; Department of Oncology, Jining Tumor Hospital, Jining, China.
Zheng LJ; Department of Oncology, Affiliated Hospital of Jining Medical University, Jining, China.; Pokaż więcej
Źródło:: Andrologia [Andrologia] 2019 Jul; Vol. 51 (6), pp. e13280. Date of Electronic Publication: 2019 Apr 10.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Artemisinins/*pharmacology
HSP70 Heat-Shock Proteins/*metabolism
Prostatic Neoplasms/*drug therapy
Artemisinins/therapeutic use ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Male ; PC-3 Cells ; Prostatic Neoplasms/pathology

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