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Tytuł:
Transcriptome and open chromatin analysis reveals the process of myocardial cell development and key pathogenic target proteins in Long QT syndrome type 7.
Autorzy:
Chen P; Department of Clinical Nutrition & Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Long J; Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hua T; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Zheng Z; Department of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xiao Y; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Chen L; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Yu K; Department of Clinical Nutrition & Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
Wu W; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. .; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
Zhang S; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. .; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2024 Mar 25; Vol. 22 (1), pp. 307. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Andersen Syndrome*/diagnosis
Andersen Syndrome*/genetics
Induced Pluripotent Stem Cells*
Humans ; Chromatin/metabolism ; Transcriptome ; Mutation/genetics ; Myocytes, Cardiac/metabolism ; Potassium/metabolism
Czasopismo naukowe
Tytuł:
Vocal fingerprinting reveals a substantially smaller global population of the Critically Endangered cao vit gibbon (Nomascus nasutus) than previously thought.
Autorzy:
Wearn OR; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam. .
Trinh-Dinh H; School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Bangkok, Thailand.
Ma CY; College of Life Sciences, Guangxi Normal University, Guilin, China.
Khac Le Q; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam.
Nguyen P; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam.
Van Hoang T; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam.
Van Luong C; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam.
Van Hua T; Trung Khanh Ranger Station, Forest Protection Department, Ministry of Agriculture and Rural Development, Trung Khanh, Cao Bang, Vietnam.
Van Hoang Q; Trung Khanh Ranger Station, Forest Protection Department, Ministry of Agriculture and Rural Development, Trung Khanh, Cao Bang, Vietnam.
Fan PF; School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Duc Nguyen T; Fauna & Flora, Vietnam Programme, Hanoi, Vietnam.
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 03; Vol. 14 (1), pp. 416. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Hylobates*
Hylobatidae*
Animals ; Male ; Endangered Species ; Ecosystem
SCR Organism:
Nomascus nasutus
Czasopismo naukowe
Tytuł:
Estrogen receptor-related receptor γ uppresses hypoxia-induced angiogenesis by regulating VEGFA in endometrial cancer.
Autorzy:
Wang XX; Department of Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Hua T; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,China.
Wang HB; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan,China.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2023 Dec; Vol. 39 (1), pp. 2264411. Date of Electronic Publication: 2023 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Endometrial Neoplasms*/blood supply
Endometrial Neoplasms*/genetics
Endometrial Neoplasms*/metabolism
Endometrial Neoplasms*/pathology
Neovascularization, Pathologic*/genetics
Neovascularization, Pathologic*/metabolism
Animals ; Female ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Hypoxia ; Mice, Nude ; Receptors, Estrogen/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Hypoxia-Inducible Factor 1/metabolism
Czasopismo naukowe
Tytuł:
Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest.
Autorzy:
Hua T; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Chu Y; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Wang M; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Zhang Y; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Shi W; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Huang Q; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Zhang L; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China.
Yang M; The Second Department of Critical Care Medicine and The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui Province, China. .
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Źródło:
Intensive care medicine experimental [Intensive Care Med Exp] 2023 Nov 15; Vol. 11 (1), pp. 78. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Genome-Wide Extrachromosomal Circular DNA Profiling of Paired Hepatocellular Carcinoma and Adjacent Liver Tissues.
Autorzy:
Ye J; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Huang P; Liver Cancer Institute, Fudan University, Shanghai 200032, China.; Department of Hepatic Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Ma K; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Zhao Z; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Hua T; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Zai W; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Chen J; Key Laboratory of Medical Molecular Virology (MOE & NHC), Research Unit of Cure of Chronic Hepatitis B Virus Infection (CAMS), School of Basic Medical Sciences, Shanghai Medical College Fudan University, Shanghai 200032, China.
Fu X; Liver Cancer Institute, Fudan University, Shanghai 200032, China.; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Shanghai 200032, China.
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Źródło:
Cancers [Cancers (Basel)] 2023 Nov 07; Vol. 15 (22). Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Development of a machine learning-based prediction model for sepsis-associated delirium in the intensive care unit.
Autorzy:
Zhang Y; The Second Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.; The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.
Hu J; The Second Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.; The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.
Hua T; The Second Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.; The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.
Zhang J; The Second Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.; The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.
Zhang Z; Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3, Hangzhou, 310016, Zhejiang, People's Republic of China.
Yang M; The Second Department of Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China. .; The Laboratory of Cardiopulmonary Resuscitation and Critical Care, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 04; Vol. 13 (1), pp. 12697. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sepsis-Associated Encephalopathy*
Delirium*/diagnosis
Delirium*/etiology
Humans ; Bayes Theorem ; Intensive Care Units ; Machine Learning
Czasopismo naukowe
Tytuł:
A Sensitivity-Optimized Flexible Capacitive Pressure Sensor with Cylindrical Ladder Microstructural Dielectric Layers.
Autorzy:
Hua T; School of Materials Science and Engineering, Jiangxi Provincial Key Laboratory of Power Batteries and Materials, Jiangxi University of Sciences and Technology, Ganzhou 341000, China.; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Xiang Z; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Xia X; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Li Z; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Sun D; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Wu Y; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Liu Y; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Shang J; CAS Key Laboratory of Magnetic Materials and Devices, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.; Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology, Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences, Ningbo 315201, China.
Chen J; School of Materials Science and Engineering, Jiangxi Provincial Key Laboratory of Power Batteries and Materials, Jiangxi University of Sciences and Technology, Ganzhou 341000, China.
Li R; College of Materials Science and Opto-Electronic Technology, University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2023 Apr 27; Vol. 23 (9). Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
An action plan for the agri-food sector at the time of the climate and biodiversity crises.
Autorzy:
Cherubini F; Industrial Ecology Programme, Department of Energy and Process Engineering, Norwegian University of Science and Technology (NTNU), Norway.
Hua T; State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, China.; Institute of Land Surface System and Sustainable Development, Faculty of Geographical Science, Beijing Normal University, China.
Zhao W; State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, China.; Institute of Land Surface System and Sustainable Development, Faculty of Geographical Science, Beijing Normal University, China.
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Źródło:
National science review [Natl Sci Rev] 2023 Mar 17; Vol. 10 (7), pp. nwad076. Date of Electronic Publication: 2023 Mar 17 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Long non‑coding RNA DSCAM‑AS1 functions as an oncogene in thyroid cancer via regulating miR‑211.
Autorzy:
Hua T; Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, P.R. China.; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
Yang J; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
Zhu Y; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
Luo Y; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
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Źródło:
Oncology letters [Oncol Lett] 2023 Mar 08; Vol. 25 (4), pp. 165. Date of Electronic Publication: 2023 Mar 08 (Print Publication: 2023).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
mDIXON-Quant technique diagnostic accuracy for assessing bone mineral density in male adult population.
Autorzy:
Tang R; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China.
Tang G; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China.
Hua T; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China.
Tu Y; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China.
Ji R; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China.
Zhu J; Department of Radiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China. .
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Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2023 Feb 14; Vol. 24 (1), pp. 125. Date of Electronic Publication: 2023 Feb 14.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoporosis*/diagnostic imaging
Bone Diseases, Metabolic*/diagnostic imaging
Adult ; Humans ; Male ; Bone Density ; Magnetic Resonance Imaging/methods ; Lumbar Vertebrae/diagnostic imaging ; Absorptiometry, Photon
Czasopismo naukowe
Tytuł:
Soft Actor-Critic-Driven Adaptive Focusing under Obstacles.
Autorzy:
Lu H; Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.
Zhu R; Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.; School of Information and Electrical Engineering, Hangzhou City University, Hangzhou 310015, China.
Wang C; Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.
Hua T; Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.
Zhang S; Interdisciplinary Center for Quantum Information, State Key Laboratory of Modern Optical Instrumentation, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 310027, China.
Chen T; China Aeronautical Establishment, Beijing 100029, China.
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Źródło:
Materials (Basel, Switzerland) [Materials (Basel)] 2023 Feb 06; Vol. 16 (4). Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
AKT Regulation of ORAI1-Mediated Calcium Influx in Breast Cancer Cells.
Autorzy:
Bong AHL; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Hua T; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
So CL; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Peters AA; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Robitaille M; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Tan YY; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Roberts-Thomson SJ; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Monteith GR; School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.; Mater Research, Translational Research Institute, The University of Queensland, Brisbane, QLD 4101, Australia.
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Źródło:
Cancers [Cancers (Basel)] 2022 Sep 30; Vol. 14 (19). Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Validating ORR and PFS as surrogate endpoints in phase II and III clinical trials for NSCLC patients: difference exists in the strength of surrogacy in various trial settings.
Autorzy:
Hua T; Present Address: Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China.; Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Gao Y; Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Zhang R; Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Wei Y; Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Chen F; Present Address: Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China. .; Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China. .
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Źródło:
BMC cancer [BMC Cancer] 2022 Sep 29; Vol. 22 (1), pp. 1022. Date of Electronic Publication: 2022 Sep 29.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/therapy
Lung Neoplasms*/therapy
Biomarkers ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Humans ; Immunotherapy ; Survival Analysis
Czasopismo naukowe
Tytuł:
Structural basis for strychnine activation of human bitter taste receptor TAS2R46.
Autorzy:
Xu W; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Wu L; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Liu S; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Liu X; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Cao X; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhou C; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhang J; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Fu Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Guo Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Wu Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Tan Q; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Wang L; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Liu J; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Jiang L; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Fan Z; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Pei Y; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.
Yu J; School of Information Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Cheng J; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhao S; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Hao X; State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650210, China.
Liu ZJ; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Hua T; iHuman Institute, ShanghaiTech University, Shanghai 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Sep 16; Vol. 377 (6612), pp. 1298-1304. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
Neurotoxins*/pharmacology
Receptors, G-Protein-Coupled*/agonists
Receptors, G-Protein-Coupled*/chemistry
Strychnine*/pharmacology
Taste*/drug effects
Cryoelectron Microscopy ; Humans ; Ligands ; Protein Conformation
Czasopismo naukowe
Tytuł:
Circular RNA PVT1 promotes progression of thyroid cancer by competitively binding miR-384.
Autorzy:
Hua T; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
Luo Y; Department of Thyroid Breast Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo, Zhejiang 315040, P.R. China.
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Źródło:
Experimental and therapeutic medicine [Exp Ther Med] 2022 Aug 19; Vol. 24 (4), pp. 629. Date of Electronic Publication: 2022 Aug 19 (Print Publication: 2022).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Two-Dimensional Detergent Expansion Strategy for Membrane Protein Studies.
Autorzy:
Zhao F; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Zhu Z; College of Chemistry, Nanchang University, Nanchang, Jiangxi Province, 330031, China.
Xie L; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Luo F; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Wang H; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Qiu Y; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Luo W; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhou F; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Xue D; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Zhang Z; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Hua T; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Wu D; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.
Liu ZJ; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Le Z; College of Chemistry, Nanchang University, Nanchang, Jiangxi Province, 330031, China.
Tao H; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; Shanghai Frontiers Science Center of TCM Chemical Biology, Innovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Aug 04; Vol. 28 (44), pp. e202201388. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji:
Journal Article
MeSH Terms:
Detergents*/chemistry
Membrane Proteins*/chemistry
Magnetic Resonance Spectroscopy ; Micelles
Czasopismo naukowe
Tytuł:
Human Malignant Rhabdoid Tumor Antigens as Biomarkers and Potential Therapeutic Targets.
Autorzy:
Hua T; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
Zeng Z; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
Chen J; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
Xue Y; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.
Li Y; Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, FL 32310-6046, USA.; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380, USA.
Sang Q; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA.; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380, USA.
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Źródło:
Cancers [Cancers (Basel)] 2022 Jul 28; Vol. 14 (15). Date of Electronic Publication: 2022 Jul 28.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Phenotypic, metabolic, and biogenesis properties of human stem cell-derived cerebellar spheroids.
Autorzy:
Hua T; Department of Chemistry and Biochemistry, Florida State University, 102 Varsity Way, Tallahassee, FL, 32306, USA.
Liu C; Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, 2525 Pottsdamer St., Tallahassee, FL, 32310, USA.
Kiran S; Department of Chemistry and Biochemistry, Florida State University, 102 Varsity Way, Tallahassee, FL, 32306, USA.
Gray K; PBS Biotech Inc., Camarillo, CA, USA.
Jung S; PBS Biotech Inc., Camarillo, CA, USA.
Meckes DG Jr; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL, USA.
Li Y; Department of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, 2525 Pottsdamer St., Tallahassee, FL, 32310, USA. .; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, USA. .
Sang QA; Department of Chemistry and Biochemistry, Florida State University, 102 Varsity Way, Tallahassee, FL, 32306, USA. .; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 27; Vol. 12 (1), pp. 12880. Date of Electronic Publication: 2022 Jul 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cerebellum*/cytology
Hedgehog Proteins*/metabolism
Induced Pluripotent Stem Cells*/cytology
Spheroids, Cellular*/metabolism
Humans ; Neurons/metabolism ; Tretinoin/metabolism ; Zinc/metabolism
Czasopismo naukowe
Tytuł:
Huc-MSCs-derived exosomes attenuate inflammatory pain by regulating microglia pyroptosis and autophagy via the miR-146a-5p/TRAF6 axis.
Autorzy:
Hua T; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Yang M; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Song H; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Kong E; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Deng M; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Li Y; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Li J; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China.
Liu Z; Research Center of Developmental Biology, Department of Histology and Embryology, College of Basic Medicine, Naval Medical University, Shanghai, 200433, China.
Fu H; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China. .
Wang Y; Stem Cell and Regeneration Medicine Institute, Research Center of Translational Medicine, Naval Medical University, Shanghai, 200433, China. .
Yuan H; Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, 200003, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2022 Jul 14; Vol. 20 (1), pp. 324. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Autophagy ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Microglia/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pain ; Pyroptosis ; Quality of Life ; TNF Receptor-Associated Factor 6/genetics ; TNF Receptor-Associated Factor 6/metabolism
Czasopismo naukowe
Tytuł:
Mechanisms of Surround Suppression Effect on the Contrast Sensitivity of V1 Neurons in Cats.
Autorzy:
Yu H; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Xu F; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Hu X; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Tu Y; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Zhang Q; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Ye Z; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
Hua T; College of Life Sciences, Anhui Normal University, Wuhu, Anhui 241000, China.
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Źródło:
Neural plasticity [Neural Plast] 2022 Mar 08; Vol. 2022, pp. 5677655. Date of Electronic Publication: 2022 Mar 08 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Contrast Sensitivity*
Visual Cortex*/physiology
Animals ; Cats ; Neurons/physiology ; Photic Stimulation/methods
Czasopismo naukowe

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