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Tytuł :
Implication of ZNF217 in Accelerating Tumor Development and Therapeutically Targeting ZNF217-Induced PI3K-AKT Signaling for the Treatment of Metastatic Osteosarcoma.
Autorzy :
Smeester BA; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Draper GM; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Slipek NJ; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Larsson AT; Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota.; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Stratton N; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Pomeroy EJ; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Becklin KL; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Yamamoto K; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Williams KB; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Laoharawee K; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Peterson JJ; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Abrahante JE; UMII, University of Minnesota, Minneapolis, Minnesota.
Rathe SK; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Mills LJ; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Crosby MR; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Hudson WA; AHCSH Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Rahrmann EP; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England.
Largaespada DA; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Moriarity BS; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota. .
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Źródło :
Molecular cancer therapeutics [Mol Cancer Ther] 2020 Dec; Vol. 19 (12), pp. 2528-2541. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma.
Autorzy :
Smeester BA; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Slipek NJ; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Pomeroy EJ; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Laoharawee K; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Osum SH; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Larsson AT; Masonic Cancer Center, University of Minnesota, United States of America.
Williams KB; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Stratton N; Department of Pediatrics, University of Minnesota, United States of America.
Yamamoto K; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America.
Peterson JJ; Department of Pediatrics, University of Minnesota, United States of America.
Rathe SK; Department of Pediatrics, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Mills LJ; Department of Pediatrics, University of Minnesota, United States of America; Childhood Cancer Genomics Group, University of Minnesota, United States of America.
Hudson WA; Department of Pediatrics, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Crosby MR; Department of Pediatrics, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Wang M; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America.
Rahrmann EP; Cancer Research UK Cambridge Institute, University of Cambridge, United Kingdom of Great Britain and Northern Ireland.
Moriarity BS; Department of Pediatrics, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America. Electronic address: .
Largaespada DA; Department of Pediatrics, University of Minnesota, United States of America; Department of Genetics, Cell Biology and Development, University of Minnesota, United States of America; Center for Genome Engineering, University of Minnesota, United States of America; Masonic Cancer Center, University of Minnesota, United States of America. Electronic address: .
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Źródło :
Bone [Bone] 2020 Jul; Vol. 136, pp. 115353. Date of Electronic Publication: 2020 Apr 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Macrophage Colony-Stimulating Factor*
Osteosarcoma*/drug therapy
Osteosarcoma*/genetics
Aminopyridines ; Animals ; Carcinogenesis ; Mice ; Pyrroles ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
Czasopismo naukowe
Tytuł :
Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.
Autorzy :
Tschida BR; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Temiz NA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Kuka TP; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Lee LA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Riordan JD; Pacific Northwest Research Institute, Seattle, Washington.
Tierrablanca CA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Hullsiek R; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Wagner S; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Hudson WA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Linden MA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Amin K; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Beckmann PJ; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Heuer RA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Sarver AL; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota.
Yang JD; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Roberts LR; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Nadeau JH; Pacific Northwest Research Institute, Seattle, Washington.
Dupuy AJ; Department of Anatomy and Cell Biology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Keng VW; The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China. .; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong.
Largaespada DA; Department of Pediatrics, Masonic Cancer Center and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota. .
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Źródło :
Cancer research [Cancer Res] 2017 Dec 01; Vol. 77 (23), pp. 6576-6588. Date of Electronic Publication: 2017 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Hepatocellular/*genetics
Fatty Liver/*genetics
Fatty Liver/*pathology
Liver Neoplasms/*genetics
Mutagenesis, Insertional/*genetics
Transposases/*genetics
Animals ; Carcinoma, Hepatocellular/pathology ; Cell Transformation, Neoplastic/genetics ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; DNA Transposable Elements/genetics ; Female ; Humans ; Liver/pathology ; Liver Neoplasms/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mutagenesis/genetics ; N-Terminal Acetyltransferase E/biosynthesis ; N-Terminal Acetyltransferases ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
The cognitive behavior survey: testing for factorial validity and time invariance across two years of medical school.
Autorzy :
Nagel RW; Medicine Administration, Ohio State University College of Medicine, Columbus, Ohio 43015, USA. />Way DP
Hudson WA
Westman JA
Hitchcock CL
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Źródło :
Teaching and learning in medicine [Teach Learn Med] 2012; Vol. 24 (2), pp. 133-9.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Behavior*
Cognition*
Schools, Medical*
Surveys and Questionnaires/*standards
Education, Medical, Undergraduate ; Factor Analysis, Statistical ; Humans ; Longitudinal Studies ; Models, Theoretical ; Ohio ; Students, Medical/psychology
Czasopismo naukowe
Tytuł :
A role for MEIS1 in MLL-fusion gene leukemia.
Autorzy :
Kumar AR; Masonic Cancer Center, Minneapolis, MN 55455, USA.
Li Q
Hudson WA
Chen W
Sam T
Yao Q
Lund EA
Wu B
Kowal BJ
Kersey JH
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Źródło :
Blood [Blood] 2009 Feb 19; Vol. 113 (8), pp. 1756-8. Date of Electronic Publication: 2008 Dec 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Homeodomain Proteins/*genetics
Leukemia/*genetics
Leukemia/*pathology
Myeloid-Lymphoid Leukemia Protein/*genetics
Neoplasm Proteins/*genetics
Animals ; Apoptosis/physiology ; Cell Cycle/physiology ; Cell Differentiation/physiology ; Cell Line, Tumor ; Gene Knock-In Techniques ; Gene Rearrangement ; Histone-Lysine N-Methyltransferase ; Humans ; Lentivirus/genetics ; Mice ; Mice, Mutant Strains ; Myeloid Ecotropic Viral Integration Site 1 Protein ; Neoplasm Transplantation
Czasopismo naukowe
Tytuł :
Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells.
Autorzy :
Chen W; University of Minnesota Cancer Center, University of Minnesota, 420 Delaware Street S.E., Minneapolis, MN 55455, USA.
Kumar AR
Hudson WA
Li Q
Wu B
Staggs RA
Lund EA
Sam TN
Kersey JH
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Źródło :
Cancer cell [Cancer Cell] 2008 May; Vol. 13 (5), pp. 432-40.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Transformation, Neoplastic*
Gene Expression Regulation, Neoplastic*
Leukemia/*genetics
Myeloid-Lymphoid Leukemia Protein/*genetics
Oncogene Proteins, Fusion/*genetics
Animals ; Cell Division ; Gene Dosage ; Hematopoietic Stem Cells/cytology ; Humans ; Kinetics ; Mice ; Mice, Transgenic ; Retroviridae/genetics ; Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Enhancing behavioral science education at the Ohio State University College of Medicine.
Autorzy :
Post DM; Department of Family Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USA. />Stone LC
Knutson DJ
Gutierrez TL
Sari F
Hudson WA
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Źródło :
Academic medicine : journal of the Association of American Medical Colleges [Acad Med] 2008 Jan; Vol. 83 (1), pp. 28-36.
Typ publikacji :
Journal Article
MeSH Terms :
Curriculum*/standards
Behavioral Sciences/*education
Education, Medical, Undergraduate/*organization & administration
Adult ; Education, Medical, Undergraduate/standards ; Humans ; Ohio ; Program Development ; Schools, Medical ; Teaching/methods ; Total Quality Management
Czasopismo naukowe
Tytuł :
A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy.
Autorzy :
Chen W; Cancer Center, University of Minnesota, Minneapolis, USA.
Li Q
Hudson WA
Kumar A
Kirchhof N
Kersey JH
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Źródło :
Blood [Blood] 2006 Jul 15; Vol. 108 (2), pp. 669-77. Date of Electronic Publication: 2006 Mar 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hematologic Neoplasms/*etiology
Lymphocytes/*pathology
Myeloid Cells/*pathology
Myeloid-Lymphoid Leukemia Protein/*genetics
Oncogene Proteins, Fusion/*genetics
Animals ; Cell Lineage ; Hematologic Neoplasms/pathology ; Humans ; Immunophenotyping ; Mice ; Mice, Transgenic ; Myeloid-Lymphoid Leukemia Protein/physiology ; Oncogene Proteins, Fusion/physiology ; Time Factors
Czasopismo naukowe
Tytuł :
Inter- and intra-strain genomic variation in equine herpesvirus type 1 isolates.
Autorzy :
Bonass WA; Department of Microbiology, University of Leeds, U.K.
Hudson WA
Elton DM
Killington RA
Halliburton IW
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Źródło :
Archives of virology [Arch Virol] 1994; Vol. 134 (1-2), pp. 169-78.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Variation*
Genome, Viral*
Herpesvirus 1, Equid/*genetics
Amino Acid Sequence ; Animals ; Base Sequence ; Blotting, Southern ; Cell Line ; Cloning, Molecular ; DNA Probes ; DNA, Viral ; Horses ; Molecular Sequence Data ; Restriction Mapping
Czasopismo naukowe

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