Temat: "HYDROXYUREA" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Role of hydroxyurea therapy in the prevention of organ damage in sickle cell disease: a systematic review and meta-analysis.
Autorzy:: Khargekar N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India. .
Banerjee A; Department of Transfusion Transmitted Disease, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Athalye S; Department of Transfusion Transmitted Disease, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Mahajan N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Kargutkar N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Mumbai, Parel, 400 012, India.
Tapase P; Department of Paediatric Immunology & Leukocyte Biology, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Parel, Mumbai, 400 012, India.
Madkaikar M; Department of Paediatric Immunology & Leukocyte Biology, ICMR-National Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Parel, Mumbai, 400 012, India.; Pokaż więcej
Źródło:: Systematic reviews [Syst Rev] 2024 Feb 08; Vol. 13 (1), pp. 60. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Humans ; Antisickling Agents/therapeutic use ; Albuminuria/drug therapy ; Blood Transfusion

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Skocz do pozycji: 2.

Tytuł:: Genome instability footprint under rapamycin and hydroxyurea treatments.
Autorzy:: Li J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.
Stenberg S; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Yue JX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.
Mikhalev E; Ginkgo Bioworks, Boston, Massachusetts, United States of America.
Thompson D; Ginkgo Bioworks, Boston, Massachusetts, United States of America.
Warringer J; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Liti G; Université Côte d'Azur, CNRS, INSERM, IRCAN, Nice, France.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2023 Nov 06; Vol. 19 (11), pp. e1011012. Date of Electronic Publication: 2023 Nov 06 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/pharmacology
Saccharomyces cerevisiae*/genetics
Humans ; Sirolimus/pharmacology ; Mutation ; Genomic Instability/genetics ; DNA, Ribosomal/genetics

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Skocz do pozycji: 3.

Tytuł:: Resumption of Spermatogenesis and Fertility Post Withdrawal of Hydroxyurea Treatment.
Autorzy:: Virgous C; Animal Care Facility, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37209, USA.
Lyons L; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Sakwe A; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Nayyar T; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Goodwin S; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Hildreth J; Department of Microbiology, Immunology and Physiology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Osteen K; Women's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Bruner-Tran K; Women's Reproductive Health Research Center, Department of Obstetrics and Gynecology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Alawode O; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Bourne P; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Hills ER; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.
Archibong AE; Department of Obstetrics and Gynecology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.; Department of Microbiology, Immunology and Physiology, Meharry Medical College, 1005 D.B. Todd Blvd, Nashville, TN 37208, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 27; Vol. 24 (11). Date of Electronic Publication: 2023 May 27.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/adverse effects
Hydroxyurea*/metabolism
Hypogonadism*/drug therapy
Hypogonadism*/metabolism
Female ; Male ; Mice ; Animals ; Sperm Motility ; Semen ; Spermatogenesis ; Testis/metabolism ; Fertility

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Skocz do pozycji: 4.

Tytuł:: Are Genetic Modifiers the Answer to Different Responses to Hydroxyurea Treatment?-A Pharmacogenetic Study in Sickle Cell Anemia Angolan Children.
Autorzy:: Ginete C; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Delgadinho M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Santos B; Centro de Investigação em Saúde de Angola (CISA), Bengo, Angola.; Hospital Pediátrico David Bernardino (HPDB), Luanda, Angola.
Pinto V; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Estatística e Aplicações, Universidade de Lisboa (CEAUL), 1749-016 Lisbon, Portugal.
Silva C; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Estatística e Aplicações, Universidade de Lisboa (CEAUL), 1749-016 Lisbon, Portugal.
Miranda A; Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA), 1649-016 Lisbon, Portugal.
Brito M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Investigação em Saúde de Angola (CISA), Bengo, Angola.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 15; Vol. 24 (10). Date of Electronic Publication: 2023 May 15.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/adverse effects
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/genetics
Anemia, Sickle Cell*/complications
Humans ; Pharmacogenomic Testing ; Hemolysis ; Fetal Hemoglobin/analysis

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Skocz do pozycji: 5.

Tytuł:: Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease.
Autorzy:: Pandey A; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.
Raja R; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.
Estepp JH; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.; Agios Pharmaceuticals, Cambridge, Massachusetts, USA.
Ramkrishna D; Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA.; Pokaż więcej
Źródło:: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Jun; Vol. 12 (6), pp. 748-757. Date of Electronic Publication: 2023 May 16.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/drug therapy
Humans

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Skocz do pozycji: 6.

Tytuł:: Prognostic value of modified criteria for hydroxyurea resistance or intolerance in patients with high-risk essential thrombocythemia.
Autorzy:: Park YH; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Lee S; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Mun YC; Division of Hematology-Oncology, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Park DJ; Department of Laboratory Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2023 Apr; Vol. 12 (7), pp. 8073-8082. Date of Electronic Publication: 2023 Jan 09.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Hydroxyurea*/adverse effects
Thrombocythemia, Essential*/diagnosis
Thrombocythemia, Essential*/drug therapy
Adult ; Aged ; Aged, 80 and over ; Humans ; Middle Aged ; Prognosis ; Retrospective Studies

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Skocz do pozycji: 7.

Tytuł:: Advanced clinical parameters: A complementary hydroxyurea adherence evaluation in sickle cell anemia treatment.
Autorzy:: Moreira ID; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Lessa CLM; Graduate Program in Pathology, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Rocha GLG; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.; Clinicas Hospital of Porto Alegre/RS, Porto Alegre/RS, Brazil.
Schmitz LD; Undergraduate Program in Pharmacy, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Jahnke VS; Vale do Rio dos Sinos University (UNISINOS), Porto Alegre/RS, Brazil.
Fogliatto LM; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.; Graduate Program in Pathology, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Werlang MC; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.
Rotta LN; Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre/RS, Brazil.; Pokaż więcej
Źródło:: European journal of haematology [Eur J Haematol] 2022 Dec; Vol. 109 (6), pp. 736-748. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Child ; Adult ; Adolescent ; Humans ; Antisickling Agents/therapeutic use ; Cross-Sectional Studies ; Blood Cell Count

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Skocz do pozycji: 8.

Tytuł:: The impact of Hydroxyurea on the rates of Vaso-occlusive crises in patients with sickle cell disease in Saudi Arabia: a single-center study.
Autorzy:: Alkhalifah SA; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Alanazi M; Department of Pharmacy, King Khalid University Hospital, P.O. Box 3145, Riyadh, 12372, Saudi Arabia.
Almasaoud MA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Malki HS; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Murdhi FM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Hazzaa MS; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Al-Mufarrij SM; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia.
Albabtain MA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
Alshiakh AA; College of Medicine, King Saud University, Riyadh, 11451, Saudi Arabia.
AlRuthia Y; Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. .; Pharmacoeconomics Research Unit, Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia. .; Pokaż więcej
Źródło:: BMC emergency medicine [BMC Emerg Med] 2022 Nov 29; Vol. 22 (1), pp. 188. Date of Electronic Publication: 2022 Nov 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hydroxyurea*/therapeutic use
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Female ; Humans ; Male ; Child ; Saudi Arabia/epidemiology ; Retrospective Studies ; Cognition

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Skocz do pozycji: 9.

Tytuł:: Ten-year longitudinal analysis of hydroxyurea implementation in a pediatric sickle cell program.
Autorzy:: Phan V; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Park JA; Inova Fairfax Hospital, Falls Church, Virginia, USA.
Dulman R; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Lewis A; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Briere N; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Notarangelo B; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.
Yang E; Pediatric Specialists of Virginia, Fairfax, Virginia, USA.; Department of Pediatrics, George Washington University School of Medicine, Washington, District of Columbia, USA.; Pokaż więcej
Źródło:: European journal of haematology [Eur J Haematol] 2022 Nov; Vol. 109 (5), pp. 465-473. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/epidemiology
Hydroxyurea*/therapeutic use
Antisickling Agents/therapeutic use ; Blood Transfusion ; Child ; Erythrocytes, Abnormal ; Fetal Hemoglobin ; Humans ; Infant

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Skocz do pozycji: 10.

Tytuł:: A systematic review on hydroxyurea therapy for sickle cell disease in India.
Autorzy:: Pandey A; Division of Epidemiological & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Kaur H; Division of Epidemiological & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Borah S; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, Mumbai, Maharashtra, India.
Khargekar N; Department of Haematogenetics, ICMR-National Institute of Immunohaematology, Mumbai, Maharashtra, India.
Karra VK; Division of Epidemiological & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Adhikari T; ICMR-National Institute of Medical Statistics, New Delhi, India.
Jain D; Department of Paediatrics, Government Medical College, Nagpur, Maharashtra, India.
Madkaikar M; Department of Paediatric Immunology & Leukocyte Immunology, ICMR-National Institute of Immunohaematology, Mumbai, Maharashtra, India.; Pokaż więcej
Źródło:: The Indian journal of medical research [Indian J Med Res] 2022 Aug; Vol. 156 (2), pp. 299-311.
Typ publikacji:: Systematic Review; Journal Article
MeSH Terms:: Hydroxyurea*/adverse effects
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/epidemiology
Humans ; Antisickling Agents/adverse effects ; Cross-Sectional Studies ; Prospective Studies ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 11.

Tytuł:: New Synthetic Isoxazole Derivatives Acting as Potent Inducers of Fetal Hemoglobin in Erythroid Precursor Cells Isolated from β-Thalassemic Patients.
Autorzy:: Zuccato C; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.; Center 'Chiara Gemmo and Elio Zago' for the Research on Thalassemia, University of Ferrara, 44121 Ferrara, Italy.
Cosenza LC; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.
Tupini C; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.
Finotti A; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.
Sacchetti G; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.
Simoni D; Department of Chemical, Pharmaceutical and Agricultural Sciences, Ferrara University, 44121 Ferrara, Italy.
Gambari R; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.; Center 'Chiara Gemmo and Elio Zago' for the Research on Thalassemia, University of Ferrara, 44121 Ferrara, Italy.
Lampronti I; Department of Life Sciences and Biotechnology, Section of Biochemistry and Molecular Biology, Ferrara University, 44121 Ferrara, Italy.; Center 'Chiara Gemmo and Elio Zago' for the Research on Thalassemia, University of Ferrara, 44121 Ferrara, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 19; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 19.
Typ publikacji:: Journal Article
MeSH Terms:: Fetal Hemoglobin*/genetics
beta-Thalassemia*/drug therapy
Humans ; Erythroid Precursor Cells ; Biological Assay ; Hydroxyurea/pharmacology ; Isoxazoles

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Skocz do pozycji: 12.

Tytuł:: An innovative intervention for the prevention of vaso-occlusive episodes in sickle cell disease.
Autorzy:: Jeon WJ; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Joung B; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Moon JH; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Hino C; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Park D; Department of Internal Medicine, School of Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Pham B; Department of Internal Medicine, School of Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Castillo DR; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Chong E; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Kaur S; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Grismore C; Director of Sickle Cell Servies, Loma Linda University Medical Center, Loma Linda, CA, USA.
Cao H; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.; Pokaż więcej
Źródło:: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2215575.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/therapy
Humans ; Pain/etiology ; Pain/prevention & control ; Pain/drug therapy ; Hemoglobin, Sickle ; Pain Management/adverse effects ; Hydroxyurea/therapeutic use

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Skocz do pozycji: 13.

Tytuł:: Vital Signs: Use of Recommended Health Care Measures to Prevent Selected Complications of Sickle Cell Anemia in Children and Adolescents - Selected U.S. States, 2019.
Autorzy:: Schieve LA
Simmons GM
Payne AB
Abe K
Hsu LL
Hulihan M
Pope S
Rhie S
Dupervil B
Hooper WC; Pokaż więcej
Źródło:: MMWR. Morbidity and mortality weekly report [MMWR Morb Mortal Wkly Rep] 2022 Sep 30; Vol. 71 (39), pp. 1241-1246. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/therapy
Hydroxyurea*/therapeutic use
Adolescent ; Child ; Delivery of Health Care ; Humans ; Ultrasonography, Doppler, Transcranial ; United States/epidemiology ; Vital Signs

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Skocz do pozycji: 14.

Tytuł:: Hydroxyurea does not reverse functional alterations of the nitric oxide-cGMP pathway associated with priapism phenotype in corpus cavernosum from sickle cell mouse.
Autorzy:: Pereira DA; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, São Paulo, Brazil.
Pereira DA; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, São Paulo, Brazil.
da Silva Pereira P; Hematology and Hemotherapy Center, University of Campinas, Campinas, São Paulo, Brazil.
Silveira THR; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, São Paulo, Brazil.
Calmasini FB; Escola Paulista de Medicina, Department of Pharmacology, Universidade Federal de São Paulo, São Paulo, São Paulo, Brazil.
Reis LO; UroScience, Pontifical Catholic University of Campinas, Campinas, São Paulo, Brazil.
Costa FF; Hematology and Hemotherapy Center, University of Campinas, Campinas, São Paulo, Brazil.
Silva FH; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, São Paulo, Brazil.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Oct 09; Vol. 18 (10), pp. e0292706. Date of Electronic Publication: 2023 Oct 09 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Priapism*/etiology
Priapism*/complications
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/metabolism
Humans ; Mice ; Male ; Animals ; Nitric Oxide/metabolism ; Hydroxyurea/pharmacology ; Hydroxyurea/therapeutic use ; Mice, Inbred C57BL ; Penis ; Nitroprusside/pharmacology ; Nitroprusside/metabolism ; Mice, Transgenic ; Muscle Relaxation ; Acetylcholine/metabolism ; Phenotype ; Hemoglobins/metabolism

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Skocz do pozycji: 15.

Tytuł:: Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease.
Autorzy:: Smart LR; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA. .; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, USA. .; Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, USA. .
Segbefia CI; Department of Child Health, University of Ghana Medical School, Accra, Ghana.; Department of Child Health, Korle Bu Teaching Hospital, Accra, Ghana.
Latham TS; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
Stuber SE; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.; Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
Amissah-Arthur KN; Ophthalmology Unit, Department of Surgery, University of Ghana Medical School, Accra, Ghana.; Ophthalmology Unit, Department of Surgery, Korle Bu Teaching Hospital, Accra, Ghana.
Dzefi-Tettey K; Department of Radiology, Korle Bu Teaching Hospital, Accra, Ghana.
Lane AC; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, USA.
Dei-Adomakoh YA; Department of Haematology, University of Ghana Medical School, Accra, Ghana.; Department of Haematology, Korle Bu Teaching Hospital, Accra, Ghana.; Ghana Institute of Clinical Genetics, Korle Bu, Accra, Ghana.
Ware RE; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, USA.; Global Health Center, Cincinnati Children's Hospital Medical Center, Cincinnati, USA.; Pokaż więcej
Źródło:: Trials [Trials] 2023 Sep 22; Vol. 24 (1), pp. 603. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:: Clinical Trial Protocol; Journal Article
MeSH Terms:: Hemoglobin SC Disease*
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Adult ; Child ; Humans ; Hydroxyurea/adverse effects ; Ghana ; Quality of Life ; Retrospective Studies ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 16.

Tytuł:: Health-Related Quality of Life and Adherence to Hydroxyurea and Other Disease-Modifying Therapies among Individuals with Sickle Cell Disease: A Systematic Review.
Autorzy:: Yang M; Department of Medical Education, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Elmuti L; Division of Hematology/Oncology, Comer Children's Hospital/University of Chicago, Chicago, IL, USA.
Badawy SM; Division of Hematology, Oncology, and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2022 Jul 18; Vol. 2022, pp. 2122056. Date of Electronic Publication: 2022 Jul 18 (Print Publication: 2022).
Typ publikacji:: Journal Article; Review; Systematic Review
MeSH Terms:: Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/psychology
Hydroxyurea*/therapeutic use
Humans ; Medication Adherence/psychology ; Pain/drug therapy ; Quality of Life

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Skocz do pozycji: 17.

Tytuł:: Post-remission outcomes in AML patients with high hyperleukocytosis and inaugural life-threatening complications.
Autorzy:: Fodil S; Hématologie Adulte, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.; Sorbonne Université, Paris, France.
Chevret S; Service de Biostatistique et Information Médicale, Hôpital Saint-Louis, Paris, France.
Rouzaud C; Hématologie Adulte, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Valade S; Medical Intensive Care Unit, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Rabian F; Hématologie Adolescents et Jeunes Adultes, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Mariotte E; Medical Intensive Care Unit, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Raffoux E; Hématologie Adulte, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Itzykson R; Hématologie Adulte, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Boissel N; Hématologie Adolescents et Jeunes Adultes, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Sébert M; Hématologie Seniors, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.; Université de Paris and INSERM U944, Paris, France.
Adès L; Hématologie Seniors, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.; Université de Paris and INSERM U944, Paris, France.
Zafrani L; Medical Intensive Care Unit, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Azoulay E; Medical Intensive Care Unit, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.
Lengliné E; Hématologie Adulte, Hôpital Saint-Louis, APHP, Université Paris Diderot, Paris, France.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jul 07; Vol. 17 (7), pp. e0270744. Date of Electronic Publication: 2022 Jul 07 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Hydroxyurea*/therapeutic use
Leukemia, Myeloid, Acute*/complications
Leukemia, Myeloid, Acute*/drug therapy
Humans ; Proportional Hazards Models ; Recurrence ; Remission Induction ; Retrospective Studies

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Skocz do pozycji: 18.

Tytuł:: Stability evaluation of compounded hydroxyurea 100 mg/mL oral liquids using a novel analytical method involving chemical derivatization.
Autorzy:: Coache D; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada.
Friciu M; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada.
Bernine Marcellin R; Sainte-Justine University Hospital Center, Montréal, Québec, Canada.
Bonnemain L; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada.
Viau A; Sainte-Justine University Hospital Center, Montréal, Québec, Canada.
Roullin VG; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada.
Forest JM; Sainte-Justine University Hospital Center, Montréal, Québec, Canada.
Leclair G; Faculty of Pharmacy, Université de Montréal, Montréal, Québec, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jun 24; Vol. 17 (6), pp. e0270206. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Ammonium Compounds*
Hydroxyurea*
Administration, Oral ; Amber ; Capsules ; Chromatography, High Pressure Liquid ; Drug Compounding ; Drug Stability ; Drug Storage ; Plastics ; Suspensions

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Skocz do pozycji: 19.

Tytuł:: Bringing Sickle Cell Disease Care Closer to Home: Feasibility and Efficacy of a Quality Improvement Initiative at a Community Hospital.
Autorzy:: Binding A; Department of Medicine, William Osler Health System, Brampton, ON, Canada.; University Health Network, University of Toronto, Toronto, ON, Canada.; Pokaż więcej
Źródło:: Hemoglobin [Hemoglobin] 2022 Mar; Vol. 46 (2), pp. 91-94. Date of Electronic Publication: 2022 May 13.
Typ publikacji:: Journal Article
MeSH Terms:: Anemia, Sickle Cell*/epidemiology
Anemia, Sickle Cell*/therapy
Hydroxyurea*/therapeutic use
Adult ; Antisickling Agents ; Child ; Feasibility Studies ; Hospitals, Community ; Humans ; Quality Improvement

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Skocz do pozycji: 20.

Tytuł:: Long-term clinical efficacy and safety of thalidomide in patients with transfusion-dependent β-thalassemia: results from Thal-Thalido study.
Autorzy:: Ali Z; Department of Pharmacy, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Ismail M; Department of Pharmacy, University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Rehman IU; Department of Pharmacology, Northwest School of Medicine, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Rani GF; Department of Pathology, Institute of Pathology and Diagnostic Medicine, Khyber Medical University Peshawar, Peshawar, Pakistan.
Ali M; Department of Hematology, Pak International Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Khan MTM; Department of Hematology, Pak International Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan. .; Blood Disease Clinic, Peshawar, Khyber Pakhtunkhwa, Pakistan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Aug 21; Vol. 13 (1), pp. 13592. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:: Clinical Trial; Journal Article
MeSH Terms:: Thalidomide*/adverse effects
beta-Thalassemia*/drug therapy
Humans ; Hydroxyurea/adverse effects ; Uric Acid ; Treatment Outcome ; Ferritins

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