Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Hagberg, Henrik"" wg kryterium: Autor


Tytuł :
Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia.
Autorzy :
Rodriguez J; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Xie C; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Li T; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Department of Pediatrics, Children's Hospital of Zhengzhou University, Zhengzhou, China.
Sun Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Department of Anatomy, School of Basic Medical Science, Zhengzhou University, Zhengzhou, 450001, China.
Wang Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Department of Pediatrics, Children's Hospital of Zhengzhou University, Zhengzhou, China.
Xu Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Li K; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zhang S; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zhou K; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Wang Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Mallard C; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Hagberg H; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Dept of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
Doti N; Istituto di Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, Napoli, 80134, Italy.
Wang X; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Zhu C; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address: .
Pokaż więcej
Źródło :
Neuropharmacology [Neuropharmacology] 2020 Jul; Vol. 171, pp. 108088. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis Inducing Factor/*antagonists & inhibitors
Apoptosis Inducing Factor/*pharmacology
Cyclophilins/*antagonists & inhibitors
Hypoxia-Ischemia, Brain/*prevention & control
Neuroprotective Agents/*pharmacology
Administration, Intranasal ; Animals ; Animals, Newborn ; Apoptosis/drug effects ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/pathology ; Caspases/physiology ; Cell Death/drug effects ; Female ; Gray Matter/pathology ; Hypoxia-Ischemia, Brain/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Organelle Biogenesis ; Sex Characteristics ; White Matter/pathology
Czasopismo naukowe
Tytuł :
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
Autorzy :
Li T; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital Affiliated of Zhengzhou University, Zhengzhou, 450018, China.
Li K; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Zhang S; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Wang Y; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital Affiliated of Zhengzhou University, Zhengzhou, 450018, China.
Xu Y; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Cronin SJF; Institute of Molecular Biotechnology, Austrian Academy of Sciences, 1030, Vienna, Austria.
Sun Y; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Zhang Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital Affiliated of Zhengzhou University, Zhengzhou, 450018, China.
Xie C; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Rodriguez J; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Zhou K; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Hagberg H; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Mallard C; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Wang X; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China.; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Penninger JM; Institute of Molecular Biotechnology, Austrian Academy of Sciences, 1030, Vienna, Austria.; Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, Canada.
Kroemer G; Equipe labellisée par la Ligue contre le cancer, Université Paris Descartes, Université Sorbonne Paris Cité, Université Paris Diderot, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Paris, France.; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, Villejuif, France.; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.; Suzhou Institute for Systems Biology, Chinese Academy of Sciences, Suzhou, China.; Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.
Blomgren K; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Pediatric Hematology and Oncology, Karolinska University Hospital, Stockholm, Sweden.
Zhu C; Henan Key Laboratory of Child Brain Injury, Institute of Neuroscience and Third Affiliated Hospital, Zhengzhou University, Zhengzhou, 450052, China. .; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden. .; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. .; Centre of Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden. .
Pokaż więcej
Źródło :
Cell death & disease [Cell Death Dis] 2020 Jan 30; Vol. 11 (1), pp. 77. Date of Electronic Publication: 2020 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*genetics
Apoptosis Inducing Factor/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Mitochondria/*metabolism
Animals ; Animals, Newborn ; Apoptosis Inducing Factor/genetics ; Caspase 3/metabolism ; Cell Nucleus/metabolism ; Disease Models, Animal ; Gene Ontology ; Humans ; Male ; Mice ; Mice, Transgenic ; Mitochondria/genetics ; Mitochondrial Dynamics/genetics ; Neurons/metabolism ; Protein Isoforms/metabolism ; RNA Splicing ; Transcriptome/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy.
Autorzy :
Martinello KA; Institute for Women's Health, University College London, London, United Kingdom.; Robinson Research Institute, University of Adelaide, Adelaide, Australia.
Meehan C; Institute for Women's Health, University College London, London, United Kingdom.
Avdic-Belltheus A; Institute for Women's Health, University College London, London, United Kingdom.
Lingam I; Institute for Women's Health, University College London, London, United Kingdom.
Ragab S; Institute for Women's Health, University College London, London, United Kingdom.
Hristova M; Institute for Women's Health, University College London, London, United Kingdom.
Tann CJ; Institute for Women's Health, University College London, London, United Kingdom.; Maternal, Adolescent, Reproductive and Child Health Centre, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Peebles D; Institute for Women's Health, University College London, London, United Kingdom.
Hagberg H; Centre of Perinatal Medicine & Health, Department of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.; Centre for the Developing Brain, Department of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.
Wolfs TGAM; Department of Paediatrics, University of Maastricht, Maastricht, Netherlands.
Klein N; Infection, Inflammation and Rheumatology, UCL Great Ormond Street Institute of Child Health, London, United Kingdom.
Tachtsidis I; Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Golay X; Institute of Neurology, University College London, London, United Kingdom.
Kramer BW; Department of Paediatrics, University of Maastricht, Maastricht, Netherlands.
Fleiss B; Centre for the Developing Brain, Department of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.; PROTECT, INSERM, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Gressens P; Centre for the Developing Brain, Department of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.; PROTECT, INSERM, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Robertson NJ; Institute for Women's Health, University College London, London, United Kingdom. .; Division of Neonatology, Sidra Medicine, Doha, Qatar. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2019 Jul 15; Vol. 9 (1), pp. 10184. Date of Electronic Publication: 2019 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Diseases/*physiopathology
Brain Injuries/*physiopathology
Hypoxia-Ischemia, Brain/*metabolism
Animals ; Animals, Newborn ; Asphyxia/metabolism ; Asphyxia Neonatorum/physiopathology ; Brain/metabolism ; Brain Diseases/metabolism ; Brain Injuries/metabolism ; Cell Death ; Disease Models, Animal ; Escherichia coli ; Hypoxia/metabolism ; Hypoxia/physiopathology ; Inflammation/metabolism ; Lipopolysaccharides/adverse effects ; Lipopolysaccharides/pharmacology ; Male ; Swine ; White Matter/metabolism
Czasopismo naukowe
Tytuł :
Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia-ischemia.
Autorzy :
Rodriguez J; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Zhang Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital of Zhengzhou University, Zhengzhou, China.
Li T; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital of Zhengzhou University, Zhengzhou, China.; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Xie C; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Sun Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Xu Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Zhou K; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Huo K; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.; Department of Pediatrics, Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Wang Y; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Department of Pediatrics, Children's Hospital of Zhengzhou University, Zhengzhou, China.; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Wang X; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Andersson D; Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Ståhlberg A; Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Xing Q; Institute of Biomedical Science of Fudan University, Shanghai, 201102, China.
Mallard C; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden.
Hagberg H; Center for Perinatal Medicine and Health, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Modjtahedi N; INSERM unit U1030, Gustave Roussy Cancer Campus, 94805, Villejuif, France.
Kroemer G; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Metabolomics and Cell Biology Platforms, GRCC, Villejuif, France; Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, INSERM U1138, Paris, France.; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.; Pôle de Biologie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Labex Immuno-Oncology, Paris, France.
Blomgren K; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Pediatric Hematology and Oncology, Karolinska University Hospital, Stockholm, Sweden.
Zhu C; Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, 40530, Sweden. .; Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. .
Pokaż więcej
Źródło :
Cell death & disease [Cell Death Dis] 2018 Dec 18; Vol. 10 (1), pp. 3. Date of Electronic Publication: 2018 Dec 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis Inducing Factor/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Mitochondria/*metabolism
Animals ; Animals, Newborn ; Apoptosis Inducing Factor/genetics ; Asphyxia Neonatorum/genetics ; Asphyxia Neonatorum/pathology ; Disease Models, Animal ; Humans ; Hypoxia-Ischemia, Brain/genetics ; Hypoxia-Ischemia, Brain/pathology ; Infant, Newborn ; Mice ; Mice, Knockout ; Mitochondria/genetics ; Protein Isoforms/genetics ; Protein Isoforms/metabolism
Czasopismo naukowe
Tytuł :
Magnesium sulphate induces preconditioning in preterm rodent models of cerebral hypoxia-ischemia.
Autorzy :
Koning G; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden. Electronic address: .
Lyngfelt E; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Svedin P; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Leverin AL; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Jinnai M; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Gressens P; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, United Kingdom; Inserm, U1141, Paris, France, France; Université Paris Diderot, Sorbonne Paris Cité, UMRS 1141, Paris, France.
Thornton C; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, United Kingdom.
Wang X; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Mallard C; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Hagberg H; Perinatal Center, Institutes of Neuroscience and Physiology & Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Sweden.
Pokaż więcej
Źródło :
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience [Int J Dev Neurosci] 2018 Nov; Vol. 70, pp. 56-66. Date of Electronic Publication: 2018 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Ischemic Preconditioning*
Hypoxia-Ischemia, Brain/*pathology
Magnesium Sulfate/*therapeutic use
Neuroprotective Agents/*therapeutic use
Animals ; Animals, Newborn ; Brain/pathology ; Carotid Artery Injuries/physiopathology ; Disease Models, Animal ; Female ; Gray Matter/pathology ; Hypoxia-Ischemia, Brain/prevention & control ; Magnesium/metabolism ; Mice ; Mice, Inbred C57BL ; Obstetric Labor, Premature ; Pregnancy ; Rats ; Rats, Wistar ; White Matter/pathology
Czasopismo naukowe
Tytuł :
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Autorzy :
Smith PLP; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.
Mottahedin A; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.
Svedin P; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.
Mohn CJ; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.
Hagberg H; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.; Institute of Clinical Sciences, Department of Obstetrics and Gynaecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ek J; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden.
Mallard C; Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, SE-405 30, Gothenburg, Sweden. .
Pokaż więcej
Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2018 Oct 30; Vol. 15 (1), pp. 301. Date of Electronic Publication: 2018 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Hypoxia-Ischemia, Brain/*immunology
Hypoxia-Ischemia, Brain/*pathology
Myeloid Cells/*physiology
Animals ; Animals, Newborn ; Antibodies/pharmacology ; Antigens, Ly/metabolism ; Calcium-Binding Proteins/metabolism ; Cytokinins/genetics ; Cytokinins/immunology ; Cytokinins/metabolism ; Disease Models, Animal ; Functional Laterality/physiology ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microfilament Proteins/metabolism ; Monocytes/drug effects ; Monocytes/pathology ; Muramidase/genetics ; Muramidase/metabolism ; Nerve Tissue Proteins/metabolism ; Neutrophils/drug effects ; Neutrophils/pathology
Czasopismo naukowe
Tytuł :
Neuroprotective exendin-4 enhances hypothermia therapy in a model of hypoxic-ischaemic encephalopathy.
Autorzy :
Rocha-Ferreira E; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.; EGA Institute for Women's Health, University College London, UK.
Poupon L; UCL School of Pharmacy, University College London, UK.
Zelco A; UCL School of Pharmacy, University College London, UK.
Leverin AL; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Nair S; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Jonsdotter A; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Carlsson Y; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
Thornton C; Department of Women and Children's Health, Centre for the Developing Brain, School of Life Course Sciences, King's College London, UK.
Hagberg H; Centre of Perinatal Medicine and Health, Institute of Clinical Sciences, Department of Obstetrics and Gynecology & Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.; Department of Perinatal Imaging and Health, Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King s College London, UK.
Rahim AA; UCL School of Pharmacy, University College London, UK.
Pokaż więcej
Źródło :
Brain : a journal of neurology [Brain] 2018 Oct 01; Vol. 141 (10), pp. 2925-2942.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*drug effects
Exenatide/*pharmacology
Hypoxia-Ischemia, Brain/*pathology
Neuroprotective Agents/*pharmacology
Animals ; Animals, Newborn ; Brain/pathology ; Disease Models, Animal ; Humans ; Hypothermia, Induced ; Mice
Czasopismo naukowe
Tytuł :
Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury.
Autorzy :
Thornton C; Perinatal Brain Injury Group, Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.
Jones A; Perinatal Brain Injury Group, Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.
Nair S; Perinatal Center, Department of Physiology, Institute of Physiology and Neuroscience, Sahlgrenska Academy, University of Gothenburg, Sweden.
Aabdien A; Perinatal Brain Injury Group, Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.
Mallard C; Perinatal Center, Department of Physiology, Institute of Physiology and Neuroscience, Sahlgrenska Academy, University of Gothenburg, Sweden.
Hagberg H; Perinatal Brain Injury Group, Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.; Perinatal Center, Department of Clinical Sciences & Physiology and Neuroscience, Sahlgrenska Academy, University of Gothenburg, Sweden.
Pokaż więcej
Źródło :
FEBS letters [FEBS Lett] 2018 Mar; Vol. 592 (5), pp. 812-830. Date of Electronic Publication: 2017 Dec 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mitophagy*
Organelle Biogenesis*
Asphyxia Neonatorum/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Mitochondria/*metabolism
Asphyxia Neonatorum/genetics ; Asphyxia Neonatorum/pathology ; Humans ; Hypoxia-Ischemia, Brain/genetics ; Hypoxia-Ischemia, Brain/pathology ; Infant, Newborn ; Mitochondria/genetics ; Mitochondria/pathology
Czasopismo naukowe
Tytuł :
γδ T Cells Contribute to Injury in the Developing Brain.
Autorzy :
Albertsson AM; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Zhang X; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Provincial Key Laboratory of Child Brain Injury, Zhengzhou, China.
Vontell R; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, St. Thomas' Hospital, London, United Kingdom.
Bi D; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Bronson RT; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School, Boston, Massachusetts.
Supramaniam V; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, St. Thomas' Hospital, London, United Kingdom.
Baburamani AA; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, St. Thomas' Hospital, London, United Kingdom.
Hua S; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Cardiovascular Medicine, Luwan Branch of Shanghai Jiaotong University Medical School Ruijin Hospital, Shanghai, China.
Nazmi A; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Cardell S; Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Zhu C; Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Henan Provincial Key Laboratory of Child Brain Injury, Zhengzhou, China; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Cantor H; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School, Boston, Massachusetts.
Mallard C; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hagberg H; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Centre for the Developing Brain, Department of Perinatal Imaging and Health, King's College London, St. Thomas' Hospital, London, United Kingdom; Department of Clinical Sciences, East Hospital, Gothenburg, Sweden.
Leavenworth JW; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama; Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: .
Wang X; Perinatal Center, Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Electronic address: .
Pokaż więcej
Źródło :
The American journal of pathology [Am J Pathol] 2018 Mar; Vol. 188 (3), pp. 757-767. Date of Electronic Publication: 2017 Dec 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Hypoxia-Ischemia, Brain/*pathology
Intraepithelial Lymphocytes/*pathology
Leukomalacia, Periventricular/*pathology
Animals ; Brain/metabolism ; Disease Models, Animal ; Female ; Humans ; Hypoxia-Ischemia, Brain/metabolism ; Interferon-gamma/metabolism ; Interleukin-17/metabolism ; Intraepithelial Lymphocytes/metabolism ; Leukomalacia, Periventricular/metabolism ; Male ; Mice ; Sheep
Czasopismo naukowe
Tytuł :
Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury.
Autorzy :
Thornton C; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, U.K. .
Baburamani AA; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, U.K.
Kichev A; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, U.K.
Hagberg H; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, U.K.; Perinatal Center, Institute of for Clinical Sciences and Physiology and Neurosciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 41685, Sweden.
Pokaż więcej
Źródło :
Biochemical Society transactions [Biochem Soc Trans] 2017 Oct 15; Vol. 45 (5), pp. 1067-1076. Date of Electronic Publication: 2017 Sep 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Asphyxia Neonatorum/*complications
Hypoxia-Ischemia, Brain/*etiology
Reactive Oxygen Species/*metabolism
Animals ; Asphyxia Neonatorum/drug therapy ; Asphyxia Neonatorum/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Humans ; Hypoxia-Ischemia, Brain/drug therapy ; Hypoxia-Ischemia, Brain/metabolism ; Infant, Newborn ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł :
Immune responses in perinatal brain injury.
Autorzy :
Lai JCY; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden.
Rocha-Ferreira E; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden.
Ek CJ; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden.
Wang X; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden.
Hagberg H; Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden.
Mallard C; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Box 432, 405 30 Gothenburg, Sweden. Electronic address: .
Pokaż więcej
Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2017 Jul; Vol. 63, pp. 210-223. Date of Electronic Publication: 2016 Nov 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Brain/*immunology
Hypoxia-Ischemia, Brain/*immunology
Immunity, Maternally-Acquired/*immunology
Animals ; Animals, Newborn ; Brain Injuries/immunology ; Female ; Humans ; Infant, Newborn ; Pregnancy ; Rodentia
Czasopismo naukowe
Tytuł :
Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic-ischemic brain injury.
Autorzy :
Morán J; Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Stokowska A; Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Walker FR; School of Biomedical Sciences and Pharmacy, University of Newcastle, New South Wales, Australia.
Mallard C; Perinatal Center, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hagberg H; Perinatal Center, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Centre for the Developing Brain, King's College, London, UK; Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Pekna M; Center for Brain Repair and Rehabilitation, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; Hunter Medical Research Institute, University of Newcastle, New South Wales, Australia. Electronic address: .
Pokaż więcej
Źródło :
Experimental neurology [Exp Neurol] 2017 Apr; Vol. 290, pp. 74-84. Date of Electronic Publication: 2017 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Cognition Disorders/*drug therapy
Cognition Disorders/*psychology
Complement C3a/*therapeutic use
Hypoxia-Ischemia, Brain/*drug therapy
Hypoxia-Ischemia, Brain/*psychology
Neuroprotective Agents/*therapeutic use
Animals ; Animals, Newborn ; Brain/pathology ; Cell Death/drug effects ; Cognition Disorders/etiology ; Complement C3a/administration & dosage ; Disease Models, Animal ; Exploratory Behavior/drug effects ; GAP-43 Protein/biosynthesis ; GAP-43 Protein/genetics ; Gliosis/prevention & control ; Hippocampus/pathology ; Hypoxia-Ischemia, Brain/etiology ; Injections, Intraventricular ; Male ; Mice ; Mice, Inbred C57BL ; Motor Activity/drug effects ; Neuroprotective Agents/administration & dosage ; Recognition, Psychology/drug effects ; Synapsins/biosynthesis
Czasopismo naukowe
Tytuł :
Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain.
Autorzy :
Mottahedin A; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Svedin P; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Nair S; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mohn CJ; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Wang X; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hagberg H; 2 Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.; 3 Perinatal Center, Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ek J; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mallard C; 1 Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Pokaż więcej
Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2017 Apr; Vol. 37 (4), pp. 1192-1198. Date of Electronic Publication: 2017 Jan 01.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Mitochondria/*metabolism
Oxygen/*metabolism
Toll-Like Receptor 2/*metabolism
Animals ; Animals, Newborn ; Brain/growth & development ; Female ; Ligands ; Lipopeptides/pharmacology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Toll-Like Receptor 2/genetics
Czasopismo naukowe
Tytuł :
Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia.
Autorzy :
Baburamani AA; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.; Perinatal Center, Institute of Neuroscience and Physiology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
Sobotka KS; Perinatal Center, Institute of Neuroscience and Physiology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
Vontell R; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.
Mallard C; Perinatal Center, Institute of Neuroscience and Physiology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
Supramaniam VG; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.
Thornton C; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.
Hagberg H; Perinatal Brain Injury Group, Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, United Kingdom.; Perinatal Center, Institute of Neuroscience and Physiology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden.
Pokaż więcej
Źródło :
Oncotarget [Oncotarget] 2017 Feb 14; Vol. 8 (7), pp. 12081-12092.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*metabolism
Brain Injuries/*genetics
Hypoxia-Ischemia, Brain/*genetics
Tumor Suppressor Protein p53/*genetics
Animals ; Animals, Newborn ; Brain/pathology ; Brain Injuries/etiology ; Calcium-Calmodulin-Dependent Protein Kinase Type 4/genetics ; Calcium-Calmodulin-Dependent Protein Kinase Type 4/metabolism ; Disease Models, Animal ; Heterozygote ; Humans ; Hypoxia-Ischemia, Brain/complications ; In Situ Hybridization ; Mice, Knockout ; Mice, Transgenic ; Time Factors ; Tumor Suppressor Protein p53/deficiency
Czasopismo naukowe
Tytuł :
Heme Oxygenase-1 Mediates Neuroprotection Conferred by Argon in Combination with Hypothermia in Neonatal Hypoxia-Ischemia Brain Injury.
Autorzy :
Zhao H; From the Faculty of Medicine, Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, Chelsea and Westminster Hospital, London, United Kingdom (H.Z., S.M., S.K., Y.T.C., M.T., D.M.); Department of Anesthesiology, The Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China (Q.L.); Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, St. Thomas' Hospital, London, United Kingdom (H.H.); Perinatal Center, Institute of Physiology and Neurosciences and Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (H.H.); and Reproductive Biology, Department of Surgery and Cancer, Imperial College London, Chelsea and Westminster Hospital, London, United Kingdom (M.R.J.).
Mitchell S
Koumpa S
Cui YT
Lian Q
Hagberg H
Johnson MR
Takata M
Ma D
Pokaż więcej
Źródło :
Anesthesiology [Anesthesiology] 2016 Jul; Vol. 125 (1), pp. 180-92.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Argon/*pharmacology
Argon/*therapeutic use
Heme Oxygenase-1/*metabolism
Hypothermia, Induced/*methods
Hypoxia-Ischemia, Brain/*therapy
Neuroprotective Agents/*pharmacology
Neuroprotective Agents/*therapeutic use
Animals ; Animals, Newborn ; Astrocytes/drug effects ; Cell Death/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Combined Modality Therapy ; Cytochromes c/metabolism ; Female ; Glycogen Synthase Kinase 3/antagonists & inhibitors ; Glycogen Synthase Kinase 3/biosynthesis ; Hypoxia-Ischemia, Brain/drug therapy ; Neurons/drug effects ; Pregnancy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Role of mitochondria in apoptotic and necroptotic cell death in the developing brain.
Autorzy :
Thornton C; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, United Kingdom.
Hagberg H; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, United Kingdom; Perinatal Center, Department of Clinical Sciences & Physiology and Neuroscience, Sahlgrenska Academy, Gothenburg University, Sweden.
Pokaż więcej
Źródło :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2015 Dec 07; Vol. 451 (Pt A), pp. 35-8. Date of Electronic Publication: 2015 Feb 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Apoptosis*
Hypoxia-Ischemia, Brain/*pathology
Mitochondria/*pathology
Necrosis/*pathology
Animals ; Cell Death ; Humans ; Hypoxia-Ischemia, Brain/metabolism ; Mitochondria/metabolism ; Necrosis/metabolism ; Neurons/metabolism ; Neurons/pathology
Czasopismo naukowe
Tytuł :
Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.
Autorzy :
Baburamani AA; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. .
Hurling C; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. .
Stolp H; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. .
Sobotka K; Perinatal Center, Institute for Clinical Sciences and Physiology & Neuroscience, Sahlgrenska Academy, University of Gothenburg, 41685 Gothenburg, Sweden. .
Gressens P; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. .; Inserm, U 1141, 75019 Paris, France. .; University Paris Diderot, Sorbonne Paris Cité, UMRS 1141, 75019 Paris, France. .
Hagberg H; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. henrik.hagberg@kcl.ac.uk.; Perinatal Center, Institute for Clinical Sciences and Physiology & Neuroscience, Sahlgrenska Academy, University of Gothenburg, 41685 Gothenburg, Sweden. henrik.hagberg@kcl.ac.uk.
Thornton C; Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, St. Thomas' Hospital, SE1 7EH London, UK. .
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2015 Sep 17; Vol. 16 (9), pp. 22509-26. Date of Electronic Publication: 2015 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
GTP Phosphohydrolases/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Metalloendopeptidases/*metabolism
Neurons/*metabolism
Animals ; Animals, Newborn ; Cell Hypoxia ; Cell Line ; Disease Models, Animal ; Gene Expression Regulation, Developmental ; Hypoxia-Ischemia, Brain/pathology ; Membrane Potential, Mitochondrial ; Metalloproteases/metabolism ; Mice ; Mitochondria/pathology ; Mitochondria/physiology ; Mitochondrial Proteins/metabolism ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia.
Autorzy :
Ek CJ; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
D'Angelo B; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Baburamani AA; 1] Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden [2] Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.
Lehner C; Spinal Cord Injury and Tissue Regeneration Center Salzburg, Department of Traumatology and Sport Injuries, Institute of Tendon and Bone Regeneration, Paracelsus Medical University, Salzburg, Austria; Austrian Cluster for Tissue Regeneration.
Leverin AL; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Smith PL; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Nilsson H; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Svedin P; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hagberg H; 1] Centre for the Developing Brain, Division of Imaging Sciences and Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK [2] Departments of Obstetrics and Gynecology, Institute for Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Mallard C; Department of Physiology, Institute for Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Pokaż więcej
Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2015 May; Vol. 35 (5), pp. 818-27. Date of Electronic Publication: 2015 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood-Brain Barrier*/embryology
Blood-Brain Barrier*/metabolism
Blood-Brain Barrier*/pathology
Blood-Brain Barrier*/physiopathology
Capillary Permeability*
Cerebrovascular Circulation*
Fetal Diseases*/metabolism
Fetal Diseases*/pathology
Fetal Diseases*/physiopathology
Hypoxia-Ischemia, Brain*/embryology
Hypoxia-Ischemia, Brain*/metabolism
Hypoxia-Ischemia, Brain*/pathology
Hypoxia-Ischemia, Brain*/physiopathology
Animals ; Animals, Newborn ; Disease Models, Animal ; Gene Expression Regulation ; Humans ; Mice
Czasopismo naukowe
Tytuł :
A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice.
Autorzy :
Rousset CI; Division of Imaging Sciences and Biomedical Engineering, Centre for the Developing Brain, King's College London, King's Health Partners, St. Thomas' Hospital, London, UK.
Leiper FC
Kichev A
Gressens P
Carling D
Hagberg H
Thornton C
Pokaż więcej
Źródło :
Journal of neurochemistry [J Neurochem] 2015 Apr; Vol. 133 (2), pp. 242-52. Date of Electronic Publication: 2015 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
AMP-Activated Protein Kinases/*metabolism
Brain/*metabolism
Gene Expression Regulation, Developmental/*physiology
Hypoxia-Ischemia, Brain/*enzymology
Hypoxia-Ischemia, Brain/*pathology
Animals ; Animals, Newborn ; Benzimidazoles/pharmacology ; Cell Death ; Cells, Cultured ; Disease Models, Animal ; Enzyme Inhibitors/pharmacology ; Glucose/deficiency ; Hypoxia/pathology ; Ionomycin/pharmacology ; L-Lactate Dehydrogenase/metabolism ; Mice ; Mice, Inbred C57BL ; Naphthalimides/pharmacology ; Neurons/metabolism ; Signal Transduction/physiology ; Time Factors
Czasopismo naukowe
Tytuł :
Does Caspase-6 Have a Role in Perinatal Brain Injury?
Autorzy :
Baburamani AA; Perinatal Center, Institute of Neuroscience and Physiology, Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Miyakuni Y
Vontell R
Supramaniam VG
Svedin P
Rutherford M
Gressens P
Mallard C
Takeda S
Thornton C
Hagberg H
Pokaż więcej
Źródło :
Developmental neuroscience [Dev Neurosci] 2015; Vol. 37 (4-5), pp. 321-37. Date of Electronic Publication: 2015 Mar 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*growth & development
Brain Injuries/*metabolism
Caspase 6/*metabolism
Hypoxia-Ischemia, Brain/*metabolism
Microglia/*metabolism
Animals ; Animals, Newborn ; Brain/metabolism ; Brain Injuries/etiology ; Hypoxia-Ischemia, Brain/complications ; Mice ; Mice, Knockout ; Rats
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies