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Tytuł:
Metformin Suppresses Thioacetamide-Induced Chronic Kidney Disease in Association with the Upregulation of AMPK and Downregulation of Oxidative Stress and Inflammation as Well as Dyslipidemia and Hypertension.
Autorzy:
Alshahrani MY; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61413, Saudi Arabia.
Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Alqahtani SM; Department of Surgery, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Bayoumy NM; Department of Physiology, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia.
Kamar SS; Department of Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 11566, Egypt.; Histology Department, Armed Forces College of Medicine, Cairo 11566, Egypt.
ShamsEldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 11566, Egypt.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 11566, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia.
Albawardi A; Department of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 15551, United Arab Emirates.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 18; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Metformin*/pharmacology
Metformin*/therapeutic use
Renal Insufficiency, Chronic*/metabolism
Hypertension*/chemically induced
Hypertension*/drug therapy
Hypertension*/metabolism
Dyslipidemias*/chemically induced
Dyslipidemias*/drug therapy
Dyslipidemias*/metabolism
Rats ; Animals ; AMP-Activated Protein Kinases/metabolism ; Thioacetamide/toxicity ; Tissue Inhibitor of Metalloproteinase-1/metabolism ; Up-Regulation ; Down-Regulation ; Oxidative Stress ; Inflammation/metabolism ; Fibrosis ; Liver/metabolism ; Liver Cirrhosis/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vitamin E protects against the modulation of TNF-α-AMPK axis and inhibits pancreas injury in a rat model of L-arginine-induced acute necrotising pancreatitis.
Autorzy:
Al-Hashem F; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Abd Ellatif M; Department of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
ShamsEldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2023 Feb; Vol. 129 (1), pp. 148-156. Date of Electronic Publication: 2020 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatitis, Acute Necrotizing*/chemically induced
Pancreatitis, Acute Necrotizing*/drug therapy
Pancreatitis, Acute Necrotizing*/metabolism
Humans ; Rats ; Animals ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism ; Interleukin-10/metabolism ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Vitamin E/pharmacology ; Acute Disease ; Pancreas/metabolism ; Arginine
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Suppression of knee joint osteoarthritis induced secondary to type 2 diabetes mellitus in rats by resveratrol: role of glycated haemoglobin and hyperlipidaemia and biomarkers of inflammation and oxidative stress.
Autorzy:
Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.; Department of Anatomy, College of Medicine, Mansoura University, Mansoura, Egypt.
Alzamil NM; Department of Clinical Science, Family Medicine, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Dawood AF; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2022 Oct; Vol. 128 (5), pp. 1375-1382. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/chemically induced
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Type 2*/complications
Diabetes Mellitus, Type 2*/drug therapy
Hyperlipidemias*/complications
Osteoarthritis*/drug therapy
Osteoarthritis*/etiology
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/adverse effects ; Biomarkers/metabolism ; Glycated Hemoglobin ; Inflammation/drug therapy ; Knee Joint/metabolism ; Oxidative Stress ; Proteoglycans/adverse effects ; Rats ; Resveratrol/pharmacology ; Resveratrol/therapeutic use ; Streptozocin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MiR-155 Dysregulation Is Associated with the Augmentation of ROS/p53 Axis of Fibrosis in Thioacetamide-Induced Hepatotoxicity and Is Protected by Resveratrol.
Autorzy:
Dawood AF; Department of Basic Medical Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Al Humayed S; Department of Internal Medicine, College of Medicine, King Khalid University, Abha 62529, Saudi Arabia.
Momenah MA; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh 11597, Saudi Arabia.
Ashour H; Department of Physiology, College of Medicine, King Khalid University, Abha 62529, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 12624, Egypt.
Kamar SS; Department of Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 12624, Egypt.
ShamsEldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 12624, Egypt.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo 12624, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha 62529, Saudi Arabia.
Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
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Źródło:
Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2022 Jul 21; Vol. 12 (7). Date of Electronic Publication: 2022 Jul 21.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vanadyl sulphate ameliorates biomarkers of endothelial injury and coagulation and thrombosis in a rat model of hyperglycaemia.
Autorzy:
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Bin-Jaliah I; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Shams Eldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Morsy MD; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, College of Medicine, Menoufia University, Shibin el Kom, Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2022 Apr; Vol. 128 (2), pp. 447-454. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Hyperglycemia*/complications
Thrombosis*/drug therapy
Animals ; Biomarkers ; Blood Glucose ; Rats ; Vanadium Compounds
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lipopolysaccharide induces acute lung injury and alveolar haemorrhage in association with the cytokine storm, coagulopathy and AT1R/JAK/STAT augmentation in a rat model that mimics moderate and severe Covid-19 pathology.
Autorzy:
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
ShamsEldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Hashem F; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Alshahrani MY; Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha, Saudi Arabia.; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Al-Hakami AM; Department of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Kader DHA; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Maarouf A; Department of Clinical Biochemistry, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Apr; Vol. 49 (4), pp. 483-491. Date of Electronic Publication: 2022 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Acute Lung Injury/*etiology
Blood Coagulation Disorders/*etiology
COVID-19/*pathology
Cytokine Release Syndrome/*etiology
Hemorrhage/*etiology
Lipopolysaccharides/*adverse effects
Lung Diseases/*etiology
Receptor, Angiotensin, Type 1/*metabolism
STAT Transcription Factors/*metabolism
Acute Lung Injury/pathology ; Animals ; Blood Coagulation Disorders/pathology ; COVID-19/etiology ; Cytokine Release Syndrome/pathology ; Disease Models, Animal ; Hemorrhage/pathology ; Janus Kinases ; Lung Diseases/pathology ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Suppression of glomerular damage and apoptosis and biomarkers of acute kidney injury induced by acetaminophen toxicity using a combination of resveratrol and quercetin.
Autorzy:
Dallak M; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Dawood AF; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Abdel Kader DH; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Eid RA; Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Shams Eldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
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Źródło:
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Jan; Vol. 45 (1), pp. 1-7. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji:
Journal Article
MeSH Terms:
Acute Kidney Injury*/chemically induced
Acute Kidney Injury*/metabolism
Acute Kidney Injury*/prevention & control
Chemical and Drug Induced Liver Injury*/metabolism
Acetaminophen/toxicity ; Animals ; Apoptosis ; Biomarkers/metabolism ; Endothelial Cells ; Liver/metabolism ; Oxidative Stress ; Quercetin/pharmacology ; Rats ; Resveratrol/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Resveratrol suppresses cholestasis-induced liver injury and fibrosis in rats associated with the inhibition of TGFβ1-Smad3-miR21 axis and profibrogenic and hepatic injury biomarkers.
Autorzy:
ShamsEldeen AM; Departments of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Rashed L; Medical Biochemistry and Molecular Biology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Badr AM; Medical Biochemistry and Molecular Biology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Attia A; Public Health, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Farag AM; Radiology Department, Military Medical Academy, Cairo, Egypt.
Kamar SS; Histology and Cell Biology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Haidara MA; Departments of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al Humayed S; Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Ali Eshra M; Departments of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2021 Oct; Vol. 48 (10), pp. 1402-1411. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acute Lung Injury/*drug therapy
Cholestasis/*drug therapy
Liver Cirrhosis/*drug therapy
Resveratrol/*pharmacology
Acute Lung Injury/metabolism ; Acute Lung Injury/pathology ; Animals ; Antioxidants/pharmacology ; Biomarkers/metabolism ; Cholestasis/metabolism ; Cholestasis/pathology ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Male ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Rats ; Rats, Wistar ; Smad3 Protein/genetics ; Smad3 Protein/metabolism ; Transforming Growth Factor beta1/genetics ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Captopril suppresses hepatic mammalian target of rapamycin cell signaling and biomarkers of inflammation and oxidative stress in thioacetamide-induced hepatotoxicity in rats.
Autorzy:
Al-Hashem F; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Al Humayed S; Department of Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Abdel Latif NS; Medical Pharmacology Department, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Oct; Vol. 127 (5), pp. 414-421. Date of Electronic Publication: 2019 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
Captopril*
Thioacetamide*
Animals ; Hepatocytes ; Liver ; Oxidative Stress ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insulin protects against type 1 diabetes mellitus-induced aortopathy associated with the inhibition of biomarkers of vascular injury in rats.
Autorzy:
Bin-Jaliah I; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Hewett PW; Institute of Cardiovascular Sciences, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, UK.
Al-Hashem F; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Abdel Kader DH; Department of Medical Histology, Kasr al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Morsy MD; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, College of Medicine, Menoufia University, Shibin el Kom, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Jun; Vol. 127 (3), pp. 266-272. Date of Electronic Publication: 2019 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Aorta/*drug effects
Diabetes Mellitus, Type 1/*complications
Insulin/*pharmacology
Vascular System Injuries/*complications
Vascular System Injuries/*prevention & control
Animals ; Aorta/pathology ; Biomarkers/metabolism ; Intercellular Adhesion Molecule-1/metabolism ; Male ; Oxidative Stress/drug effects ; Rats ; Vascular System Injuries/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Role of dietary selenium in alleviating bisphenol A toxicity of liver albino rats: Histological, ultrastructural, and biomarker assessments.
Autorzy:
Ahmed Zaki MS; Anatomy Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Histology Department, College of Medicine, Zagazig University, Zagazig, Egypt.
Haidara MA; Physiology Department, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Abdallaa AM; Anatomy Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mohammed H; Anatomy Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Sideeg AM; Anatomy Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Eid RA; Pathology Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
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Źródło:
Journal of food biochemistry [J Food Biochem] 2021 May; Vol. 45 (5), pp. e13725. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Selenium*/pharmacology
Animals ; Benzhydryl Compounds/toxicity ; Biomarkers ; Liver ; Male ; Phenols ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Resveratrol ameliorates type 2 diabetes mellitus-induced alterations to the knee joint articular cartilage ultrastructure in rats.
Autorzy:
El-Bidawy MH; Department of BMS, Division of Physiology, College of Medicine, Prince Sattam Ibin Abdulaziz University, Al-Kharj, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Omar Hussain AB; Department of Cardiology, College of Medicine, Prince Sattam Ibin Abdulaziz University, Al-Kharj,Saudi Arabia.
Al-Ghamdi S; Department of Family &community Medicine,College of Medicine, Prince Sattam Ibin Abdulaziz University, Al-Kharj, Saudi Arabia.
Aldossari KK; Department of Family &community Medicine, College of Medicine, Prince Sattam Ibin Abdulaziz University, Al-Kharj,Saudi Arabia.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
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Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2021 Mar 04; Vol. 45 (2), pp. 92-101. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular*
Diabetes Mellitus, Type 2*/drug therapy
Osteoarthritis*
Animals ; Chondrocytes ; Knee Joint ; Rats ; Resveratrol/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The impact of concomitant administration of vanadium and insulin on endothelial dysfunction markers (PAI-1 and ET-1) in type 1 diabetic rats.
Autorzy:
Morsy MD; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, College of Medicine, Menoufia University, Shebeen Alkoom, Egypt.
Bin-Jaliah I; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Bashir SO; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Shatoor A; Department of Cardiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2021 Feb; Vol. 127 (1), pp. 20-27. Date of Electronic Publication: 2019 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental/*therapy
Diabetes Mellitus, Type 1/*therapy
Endothelium, Vascular/*metabolism
Insulin/*administration & dosage
Vanadium/*administration & dosage
Animals ; Blood Glucose/metabolism ; C-Reactive Protein/metabolism ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/pathology ; Diabetes Mellitus, Type 1/blood ; Diabetes Mellitus, Type 1/pathology ; Endothelin-1/metabolism ; Interleukin-6/metabolism ; Male ; Malondialdehyde/metabolism ; Plasminogen Activator Inhibitor 1/metabolism ; Prospective Studies ; Rats ; Rats, Sprague-Dawley ; Superoxide Dismutase/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Grape seed extract protects against amiodarone - induced nephrotoxicity and ultrastructural alterations associated with the inhibition of biomarkers of inflammation and oxidative stress in rats.
Autorzy:
Eid RA; Pathology Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Zaki MSA; Anatomy Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Histology Department, College of Medicine, Zagazig University, Zagazig, Egypt.
Al-Shraim M; Pathology Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Eldeen MA; Biology Department, Physiology Section, Faculty of Science, Zagazig University, Zagazig, Egypt.
Haidara MA; Physiology Department, Kasr al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2021 Jan 02; Vol. 45 (1), pp. 49-58. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Amiodarone*/adverse effects
Amiodarone*/toxicity
Grape Seed Extract*/pharmacology
Animals ; Antioxidants ; Biomarkers ; Inflammation ; Oxidative Stress ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exercise augments the modulatory effects of vitamin E on pre-diabetes-induced aortopathy: a potential role of adiponectin.
Autorzy:
Dallak MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
El Karib AO; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Abd Ellatif M; Department of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Eid RA; Department of Pathology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Al-Ani R; Department of Microbiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Mahmoud HM; Department of Medical Pharmacology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2020 Oct; Vol. 126 (4), pp. 356-362. Date of Electronic Publication: 2018 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Physical Conditioning, Animal*
Adiponectin/*metabolism
Aorta/*drug effects
Aorta/*pathology
Prediabetic State/*metabolism
Vitamin E/*pharmacology
Animals ; Aorta/physiopathology ; Arterial Pressure/drug effects ; Biomarkers/metabolism ; Blood Coagulation/drug effects ; Diet, High-Fat/adverse effects ; Male ; Oxidative Stress/drug effects ; Prediabetic State/pathology ; Prediabetic State/physiopathology ; Rats ; Rats, Wistar ; Thrombosis/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metformin pretreatment suppresses alterations to the articular cartilage ultrastructure and knee joint tissue damage secondary to type 2 diabetes mellitus in rats.
Autorzy:
Dawood AF; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University , Riyadh, Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.
Alzamil N; Department of Clinical Science, Family Medicine, College of Medicine, Princess Nourah Bint Abdulrahman University , Riyadh, Saudi Arabia.
Ebrahim HA; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University , Riyadh, Saudi Arabia.; Department of Anatomy, College of Medicine, Mansoura University , Mansoura, Egypt.
Abdel Kader DH; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.
Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.
Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.; Department of Physiology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
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Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2020 May 03; Vol. 44 (3), pp. 273-282. Date of Electronic Publication: 2020 May 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular/*drug effects
Cartilage, Articular/*ultrastructure
Diabetes Mellitus, Type 2/*pathology
Hypoglycemic Agents/*pharmacology
Metformin/*pharmacology
Animals ; Cartilage, Articular/pathology ; Diabetes Mellitus, Experimental/pathology ; Inflammation/pathology ; Knee Joint/drug effects ; Knee Joint/pathology ; Knee Joint/ultrastructure ; Male ; Oxidative Stress/drug effects ; Rats
Czasopismo naukowe
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Tytuł:
Suppression of type 2 diabetes mellitus-induced aortic ultrastructural alterations in rats by insulin: an association of vascular injury biomarkers.
Autorzy:
Alzamil NM; Department of Clinical Science, Family Medicine, College of Medicine, Princess Nourah Bint Abdulrahman University , Riyadh, Saudi Arabia.
Dawood AF; Department of Basic Medical Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University , Riyadh, Saudi Arabia.; Department of Physiology, Kasr al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.
Hewett PW; Institute of Cardiovascular Sciences, College of Medicine and Dental Sciences, University of Birmingham , Birmingham, UK.
Bin-Jaliah I; Department of Physiology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
Assiri AS; Department of Medicine, College of Medicine, King Khalid University , Abha, Saudi Arabia.
Abdel Kader DH; Department of Medical Histology, Kasr al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.
Eid RA; Department of Pathology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
Haidara MA; Department of Physiology, Kasr al-Aini Faculty of Medicine, Cairo University , Cairo, Egypt.; Department of Physiology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University , Abha, Saudi Arabia.
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Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2020 May 03; Vol. 44 (3), pp. 316-323. Date of Electronic Publication: 2020 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Aorta/*ultrastructure
Diabetes Mellitus, Type 2/*complications
Hypoglycemic Agents/*pharmacology
Insulin/*pharmacology
Animals ; Aorta/pathology ; Biomarkers/blood ; Blood Glucose/drug effects ; Diabetes Mellitus, Experimental/complications ; Endothelium, Vascular/drug effects ; Male ; Muscle, Smooth, Vascular/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Swim exercise inhibits hemostatic abnormalities in a rat model of obesity and insulin resistance.
Autorzy:
Dallak M; a Department of Physiology, College of Medicine , King Khalid University , Abha , Saudi Arabia.
Bin-Jaliah I; a Department of Physiology, College of Medicine , King Khalid University , Abha , Saudi Arabia.
Sakr HF; b Department of Medical Physiology, Faculty of Medicine and Health Sciences , Sultan Qaboos University , Muscat , Oman.
Al-Ani B; a Department of Physiology, College of Medicine , King Khalid University , Abha , Saudi Arabia.
Haidara MA; a Department of Physiology, College of Medicine , King Khalid University , Abha , Saudi Arabia.; c Department of Physiology, Kasr Al-Aini Faculty of Medicine , Cairo University , Cairo , Egypt.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2019 Feb; Vol. 125 (1), pp. 79-84. Date of Electronic Publication: 2018 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Coagulation*
Insulin Resistance*
Physical Conditioning, Animal*
Swimming*
Obesity/*metabolism
Animals ; Biomarkers/metabolism ; Disease Models, Animal ; Hyperlipidemias/complications ; Male ; Obesity/complications ; Obesity/physiopathology ; Obesity/therapy ; Rats ; Rats, Wistar ; Thrombosis/complications
Czasopismo naukowe
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Tytuł:
Vitamin E ameliorates alterations to the articular cartilage of knee joints induced by monoiodoacetate and diabetes mellitus in rats.
Autorzy:
Hassan WN; Department of Clinical Biochemistry, College of Medicine, King Khalid University , Abha , Saudi Arabia.
Bin-Jaliah I; Department of Physiology, College of Medicine, King Khalid University , Abha , Saudi Arabia.
Haidara MA; Department of Physiology, College of Medicine, King Khalid University , Abha , Saudi Arabia.; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo , Egypt.
Eid RA; Department of Pathology, College of Medicine, King Khalid University , Abha , Saudi Arabia.
Heidar EHA; Department of Anatomy, Kasr Al-Aini Faculty of Medicine, Cairo University , Cairo , Egypt.; Department of Anatomy, College of Medicine, King Khalid University , Abha , Saudi Arabia.
Dallak M; Department of Physiology, College of Medicine, King Khalid University , Abha , Saudi Arabia.
Al-Ani B; Department of Physiology, College of Medicine, King Khalid University , Abha , Saudi Arabia.
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Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2019; Vol. 43 (2-3), pp. 126-134. Date of Electronic Publication: 2019 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cartilage, Articular/*drug effects
Knee Joint/*drug effects
Osteoarthritis/*drug therapy
Vitamin E/*pharmacology
Animals ; Antioxidants/pharmacology ; Chondrocytes/drug effects ; Diabetes Mellitus/drug therapy ; Disease Models, Animal ; Iodoacetic Acid ; Osteoarthritis/chemically induced ; Osteoarthritis/pathology ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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