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Tytuł :
The Messenger Apps of the cell: Extracellular Vesicles as Regulatory Messengers of Microglial Function in the CNS.
Autorzy :
Olanrewaju AA; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, 20110, USA.
Hakami RM; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, 20110, USA. .
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Źródło :
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2020 Sep; Vol. 15 (3), pp. 473-486. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Prevalence and Associated Factors of Depression among Patients with Diabetes at Jazan Province, Saudi Arabia: A Cross-Sectional Study.
Autorzy :
Madkhali JM; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Hakami AA; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Dallak AH; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Hakami RM; Medical Intern, Jazan University, Jazan, Saudi Arabia.
Yatimi AA; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Hamdi ME; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Bakkari HA; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Kariri KI; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Abiri JM; Medical Student, College of Medicine, Jazan University, Jazan, Saudi Arabia.
Ahmed AE; Associate Professor, Department of Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Mashi AH; Medical Resident, Internal Medicine Department, King Fahad Medical City, Riyadh, Saudi Arabia.
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Źródło :
Psychiatry journal [Psychiatry J] 2019 Jan 16; Vol. 2019, pp. 6160927. Date of Electronic Publication: 2019 Jan 16 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Prevalence of Psychological Distress Among Undergraduate Students at Jazan University: A Cross-Sectional Study.
Autorzy :
Hakami RM; Medical Student, College of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
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Źródło :
Saudi journal of medicine & medical sciences [Saudi J Med Med Sci] 2018 May-Aug; Vol. 6 (2), pp. 82-88. Date of Electronic Publication: 2018 Apr 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Social anxiety disorder and its impact in undergraduate students at Jazan University, Saudi Arabia.
Autorzy :
Hakami RM; Faculty of Medicine, Jazan University, Jazan.
Mahfouz MS; Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Adawi AM; Faculty of Medicine, Jazan University, Jazan.
Mahha AJ; Faculty of Medicine, Jazan University, Jazan.
Athathi AJ; Faculty of Medicine, Jazan University, Jazan.
Daghreeri HH; Faculty of Medicine, Jazan University, Jazan.
Najmi HH; Faculty of Medicine, Jazan University, Jazan.
Areeshi NA; Faculty of Medicine, Jazan University, Jazan.
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Źródło :
Mental illness [Ment Illn] 2018 Jan 03; Vol. 9 (2), pp. 7274. Date of Electronic Publication: 2018 Jan 03 (Print Publication: 2017).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1.
Autorzy :
Yi F; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Guo J; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Dabbagh D; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Spear M; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
He S; Department of Laboratory Medicine, China Medical University, Shenyang, China.
Kehn-Hall K; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Fontenot J; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Yin Y; Medicinal Chemistry, Translational Research Institute, The Scripps Research Institute, Jupiter, Florida, USA.
Bibian M; Medicinal Chemistry, Translational Research Institute, The Scripps Research Institute, Jupiter, Florida, USA.
Park CM; Medicinal Chemistry, Translational Research Institute, The Scripps Research Institute, Jupiter, Florida, USA.
Zheng K; Medicinal Chemistry, Translational Research Institute, The Scripps Research Institute, Jupiter, Florida, USA.
Park HJ; Medicinal Chemistry, Translational Research Institute, The Scripps Research Institute, Jupiter, Florida, USA.
Soloveva V; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.; Henry M. Jackson Foundation, Bethesda, Maryland, USA.
Gharaibeh D; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Retterer C; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Zamani R; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Pitt ML; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Naughton J; Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, Salk Institute of Biological Studies, La Jolla, California, USA.
Jiang Y; Department of Laboratory Medicine, China Medical University, Shenyang, China.
Shang H; Department of Laboratory Medicine, China Medical University, Shenyang, China.
Hakami RM; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Ling B; Tulane National Primate Research Center, Covington, Louisiana, USA.
Young JAT; Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, Salk Institute of Biological Studies, La Jolla, California, USA.
Bavari S; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Xu X; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, Rockville, Maryland, USA.
Feng Y; Reaction Biology Corporation, Malvern, Pennsylvania, USA .
Wu Y; National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA .
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Źródło :
Journal of virology [J Virol] 2017 Jun 09; Vol. 91 (13). Date of Electronic Publication: 2017 Jun 09 (Print Publication: 2017).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antiviral Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
HIV-1/*drug effects
Lim Kinases/*antagonists & inhibitors
Virus Release/*drug effects
Virus Replication/*drug effects
Antiviral Agents/chemical synthesis ; Antiviral Agents/isolation & purification ; Cells, Cultured ; Ebolavirus/drug effects ; Encephalitis Virus, Venezuelan Equine/drug effects ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/isolation & purification ; HIV-1/physiology ; Herpesvirus 1, Human/drug effects ; Humans ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Rift Valley fever virus/drug effects
Czasopismo naukowe
Tytuł :
S-nitrosylation of peroxiredoxin 1 contributes to viability of lung epithelial cells during Bacillus anthracis infection.
Autorzy :
Chung MC; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Alem F; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Hamer SG; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Narayanan A; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Shatalin K; Department of Biochemistry and Molecular Pharmacology and Howard Hughes Medical Institute, New York University School of Medicine, New York, NY, USA.
Bailey C; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA.
Nudler E; Department of Biochemistry and Molecular Pharmacology and Howard Hughes Medical Institute, New York University School of Medicine, New York, NY, USA.
Hakami RM; School of Systems Biology, and the National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2017 Jan; Vol. 1861 (1 Pt A), pp. 3019-3029. Date of Electronic Publication: 2016 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Anthrax/*microbiology
Anthrax/*pathology
Bacillus anthracis/*pathogenicity
Epithelial Cells/*microbiology
Epithelial Cells/*pathology
Lung/*pathology
Peroxiredoxins/*metabolism
Bacillus anthracis/drug effects ; Cell Survival/drug effects ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Gene Deletion ; Humans ; Mass Spectrometry ; Models, Biological ; Molecular Chaperones/metabolism ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type I/metabolism ; Nitrosation ; Peroxidase/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Mental Health Literacy Among Undergraduate Students of a Saudi Tertiary Institution: A Cross-sectional Study.
Autorzy :
Mahfouz MS; Department of Family and Community Medicine, Jazan University , Jazan, Saudi Arabia.
Aqeeli A; Medical Research Centre, Jazan University , Jazan, Saudi Arabia.
Makeen AM; Department of Family and Community Medicine, Jazan University, Jazan, Saudi Arabia; Medical Research Centre, Jazan University, Jazan, Saudi Arabia.
Hakami RM; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Najmi HH; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Mobarki AT; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Haroobi MH; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Almalki SM; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Mahnashi MA; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
Ageel OA; Faculty of Medicine, Jazan University , Jazan, Saudi Arabia.
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Źródło :
Mental illness [Ment Illn] 2016 Dec 21; Vol. 8 (2), pp. 6806. Date of Electronic Publication: 2016 Dec 21 (Print Publication: 2016).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Protein Phosphatase-1 regulates Rift Valley fever virus replication.
Autorzy :
Baer A; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA.
Shafagati N; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA.
Benedict A; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA.
Ammosova T; Center for Sickle Cell Disease, Department of Medicine, Howard University, Washington, D.C., USA.
Ivanov A; Center for Sickle Cell Disease, Department of Medicine, Howard University, Washington, D.C., USA.
Hakami RM; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA.
Terasaki K; Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, TX, USA.
Makino S; Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, TX, USA.
Nekhai S; Center for Sickle Cell Disease, Department of Medicine, Howard University, Washington, D.C., USA.
Kehn-Hall K; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, VA, USA. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2016 Mar; Vol. 127, pp. 79-89. Date of Electronic Publication: 2016 Jan 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antiviral Agents/*pharmacology
DNA Replication/*physiology
Indoles/*pharmacology
Protein Phosphatase 1/*metabolism
Rift Valley fever virus/*enzymology
Rift Valley fever virus/*physiology
Urea/*analogs & derivatives
Virus Replication/*physiology
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/therapeutic use ; Cell Line ; DNA Replication/drug effects ; Genome, Viral/drug effects ; Host-Pathogen Interactions ; Humans ; Phosphorylation/drug effects ; Protein Binding/drug effects ; Protein Phosphatase 1/antagonists & inhibitors ; RNA, Small Interfering/administration & dosage ; RNA, Small Interfering/genetics ; RNA, Viral/biosynthesis ; RNA, Viral/drug effects ; Rift Valley Fever/drug therapy ; Rift Valley Fever/virology ; Rift Valley fever virus/drug effects ; Rift Valley fever virus/genetics ; Urea/pharmacology ; Vero Cells ; Viral Proteins/antagonists & inhibitors ; Viral Proteins/metabolism ; Virulence ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Presence of Viral RNA and Proteins in Exosomes from Cellular Clones Resistant to Rift Valley Fever Virus Infection.
Autorzy :
Ahsan NA; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Sampey GC; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Lepene B; Ceres Nanosciences, Inc., Manassas VA, USA.
Akpamagbo Y; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Barclay RA; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Iordanskiy S; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Hakami RM; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas VA, USA.
Kashanchi F; National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, ManassasVA, USA; Laboratory of Molecular Virology, George Mason University, ManassasVA, USA.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2016 Feb 11; Vol. 7, pp. 139. Date of Electronic Publication: 2016 Feb 11 (Print Publication: 2016).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA.
Autorzy :
Sampey GC; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Saifuddin M; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Schwab A; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Barclay R; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Punya S; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Chung MC; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Hakami RM; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Zadeh MA; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110.
Lepene B; Ceres Nanosciences Inc., Manassas, Virginia 20110.
Klase ZA; the Department of Biological Sciences, University of the Sciences, Philadelphia, Pennsylvania 19104.
El-Hage N; the Department of Immunology, Herbert Wertheim College of Medicine, Miami, Florida 33199, and.
Young M; the Department of Medicine, Women's Intra-Agency HIV Study, Georgetown University, Washington, D. C. 20007.
Iordanskiy S; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110, .
Kashanchi F; From the Laboratory of Molecular Virology, George Mason University, Manassas, Virginia 20110, .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2016 Jan 15; Vol. 291 (3), pp. 1251-66. Date of Electronic Publication: 2015 Nov 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Activating Transcription Factors/*metabolism
Cytokines/*metabolism
Exosomes/*metabolism
HIV-1/*immunology
Leukocytes/*metabolism
MicroRNAs/*metabolism
Active Transport, Cell Nucleus ; Animals ; Cell Line ; Cell Line, Transformed ; Cell Transformation, Viral ; Cells, Cultured ; Exosomes/immunology ; Exosomes/virology ; HIV Infections/blood ; HIV Infections/immunology ; HIV Infections/virology ; Humans ; Interleukin-6/metabolism ; Leukocytes/immunology ; Leukocytes/virology ; Lymphotoxin-alpha/metabolism ; Mice, Inbred NOD ; Mice, Transgenic ; MicroRNAs/blood ; Toll-Like Receptor 3/antagonists & inhibitors ; Toll-Like Receptor 3/genetics ; Toll-Like Receptor 3/metabolism ; eIF-2 Kinase/antagonists & inhibitors ; eIF-2 Kinase/genetics ; eIF-2 Kinase/metabolism
Czasopismo naukowe
Tytuł :
Extracellular vesicles from infected cells: potential for direct pathogenesis.
Autorzy :
Schwab A; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA.
Meyering SS; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA ; School of Nursing and Health Studies, Georgetown University , Washington, DC, USA.
Lepene B; Ceres Nanosciences, Inc. , Manassas, VA, USA.
Iordanskiy S; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA.
van Hoek ML; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA.
Hakami RM; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA.
Kashanchi F; Laboratory of Molecular Virology, School of Systems Biology, George Mason University , Manassas, VA, USA.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2015 Oct 20; Vol. 6, pp. 1132. Date of Electronic Publication: 2015 Oct 20 (Print Publication: 2015).
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection.
Autorzy :
Chiang CY; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick MD, USA.
Uzoma I; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick MD, USA.
Lane DJ; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick MD, USA.
Memišević V; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, United States Army Medical Research and Materiel Command, Frederick MD, USA.
Alem F; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas VA, USA.
Yao K; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas VA, USA.
Kota KP; PerkinElmer, Inc., Waltham MA, USA.
Bavari S; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick MD, USA.
Wallqvist A; Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, United States Army Medical Research and Materiel Command, Frederick MD, USA.
Hakami RM; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas VA, USA.
Panchal RG; Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick MD, USA.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2015 Jul 27; Vol. 6, pp. 683. Date of Electronic Publication: 2015 Jul 27 (Print Publication: 2015).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways.
Autorzy :
Alem F; National Center for Biodefense and Infectious Diseases and School of Systems Biology, George Mason University Manassas, VA, USA.
Yao K; National Center for Biodefense and Infectious Diseases and School of Systems Biology, George Mason University Manassas, VA, USA.
Lane D; U.S. Army Medical Research Institute of Infectious Diseases Frederick, MD, USA.
Calvert V; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University Manassas, VA, USA.
Petricoin EF; Center for Applied Proteomics and Molecular Medicine, School of Systems Biology, George Mason University Manassas, VA, USA.
Kramer L; National Center for Biodefense and Infectious Diseases and School of Systems Biology, George Mason University Manassas, VA, USA.
Hale ML; U.S. Army Medical Research Institute of Infectious Diseases Frederick, MD, USA.
Bavari S; U.S. Army Medical Research Institute of Infectious Diseases Frederick, MD, USA.
Panchal RG; U.S. Army Medical Research Institute of Infectious Diseases Frederick, MD, USA.
Hakami RM; National Center for Biodefense and Infectious Diseases and School of Systems Biology, George Mason University Manassas, VA, USA.
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Źródło :
Frontiers in microbiology [Front Microbiol] 2015 Feb 13; Vol. 6, pp. 50. Date of Electronic Publication: 2015 Feb 13 (Print Publication: 2015).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The carrying pigeons of the cell: exosomes and their role in infectious diseases caused by human pathogens.
Autorzy :
Fleming A; School of Systems Biology, The National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, USA.
Sampey G
Chung MC
Bailey C
van Hoek ML
Kashanchi F
Hakami RM
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Źródło :
Pathogens and disease [Pathog Dis] 2014 Jul; Vol. 71 (2), pp. 109-20. Date of Electronic Publication: 2014 Feb 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Communication*
Cell Physiological Phenomena*
Communicable Diseases/*pathology
Communicable Diseases/*physiopathology
Exosomes/*metabolism
Humans ; Models, Biological
Czasopismo naukowe
Tytuł :
Exosomes and their role in CNS viral infections.
Autorzy :
Sampey GC; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
Meyering SS; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
Zadeh MA; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
Saifuddin M; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
Hakami RM; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
Kashanchi F; National Center for Biodefense and Infectious Diseases, and School of Systems Biology, George Mason University, Manassas, Virginia, United States of America.
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Źródło :
Journal of neurovirology [J Neurovirol] 2014 Jun; Vol. 20 (3), pp. 199-208. Date of Electronic Publication: 2014 Feb 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Central Nervous System Viral Diseases/*pathology
Central Nervous System Viral Diseases/*virology
Exosomes/*pathology
Exosomes/*virology
AIDS Dementia Complex/pathology ; AIDS Dementia Complex/virology ; Epstein-Barr Virus Infections/pathology ; Epstein-Barr Virus Infections/virology ; HTLV-I Infections/pathology ; HTLV-I Infections/virology ; Humans ; RNA, Viral
Czasopismo naukowe
Tytuł :
Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.
Autorzy :
Nuss JE; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Kehn-Hall K; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America.
Benedict A; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America.
Costantino J; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Ward M; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Peyser BD; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Retterer CJ; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Tressler LE; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Wanner LM; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
McGovern HF; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Zaidi A; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Anthony SM; University of Texas Health Sciences Center, Houston, Texas, United States of America.
Kota KP; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Bavari S; US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.
Hakami RM; School of Systems Biology, and National Center for Biodefense & Infectious Diseases, George Mason University, Manassas, Virginia, United States of America.
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Źródło :
PloS one [PLoS One] 2014 May 08; Vol. 9 (5), pp. e93483. Date of Electronic Publication: 2014 May 08 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
HSP90 Heat-Shock Proteins/*metabolism
Heat-Shock Proteins/*metabolism
Rift Valley fever virus/*metabolism
Viral Proteins/*metabolism
Virion/*metabolism
Gene Silencing ; HSP90 Heat-Shock Proteins/genetics ; Heat-Shock Proteins/genetics ; Proteomics ; RNA, Small Interfering ; Rift Valley Fever/virology ; Rift Valley fever virus/genetics ; Tandem Mass Spectrometry ; Viral Proteins/genetics ; Virion/genetics
Czasopismo naukowe
Tytuł :
Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells.
Autorzy :
Narayanan A; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Amaya M; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Voss K; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Chung M; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Benedict A; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Sampey G; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Kehn-Hall K; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Luchini A; Center for Applied Proteomics and Personalized Medicine, George Mason University, Manassas, VA, USA.
Liotta L; Center for Applied Proteomics and Personalized Medicine, George Mason University, Manassas, VA, USA.
Bailey C; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Kumar A; George Washington Medical School, Washington DC, USA.
Bavari S; United States Army Medical Research Institute for Infectious Diseases, Fredrick, MD, USA.
Hakami RM; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA.
Kashanchi F; National Center for Biodefense and Infectious Diseases, and the School of Systems Biology, George Mason University, Manassas, VA, USA. Electronic address: .
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Źródło :
Virology [Virology] 2014 Jan 20; Vol. 449, pp. 270-86. Date of Electronic Publication: 2013 Dec 15.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Apoptosis*
Liver/*cytology
Reactive Oxygen Species/*metabolism
Rift Valley Fever/*metabolism
Rift Valley fever virus/*physiology
Transcription Factor RelA/*metabolism
Tumor Suppressor Protein p53/*metabolism
Humans ; Liver/metabolism ; Liver/virology ; Oxidative Stress ; Rift Valley Fever/physiopathology ; Rift Valley Fever/virology ; Transcription Factor RelA/genetics ; Tumor Suppressor Protein p53/genetics ; Viral Nonstructural Proteins/genetics ; Viral Nonstructural Proteins/metabolism ; Virus Replication
Czasopismo naukowe
Tytuł :
In vivo murine and in vitro M-like cell models of gastrointestinal anthrax.
Autorzy :
Tonry JH; National Center for Biodefense and Infectious Diseases, George Mason University, 10650 Pyramid Place, Manassas, VA 20110, USA. />Popov SG
Narayanan A
Kashanchi F
Hakami RM
Carpenter C
Bailey C
Chung MC
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Źródło :
Microbes and infection [Microbes Infect] 2013 Jan; Vol. 15 (1), pp. 37-44. Date of Electronic Publication: 2012 Oct 26.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
Anthrax/*microbiology
Bacillus anthracis/*physiology
Gastrointestinal Diseases/*microbiology
Animals ; Anthrax/pathology ; Bacillus anthracis/pathogenicity ; Bacterial Adhesion/physiology ; Bacterial Load ; Bacterial Translocation ; Caco-2 Cells ; Female ; Gastrointestinal Diseases/pathology ; Host-Pathogen Interactions ; Humans ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/pathology ; Kaplan-Meier Estimate ; Mice ; Mice, Inbred DBA ; Spores, Bacterial
SCR Disease Name :
Gastrointestinal anthrax
Czasopismo naukowe
Tytuł :
A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors.
Autorzy :
Harris ML; Genetic Disease Research Branch, National Human Genome Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Buac K
Shakhova O
Hakami RM
Wegner M
Sommer L
Pavan WJ
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Źródło :
PLoS genetics [PLoS Genet] 2013; Vol. 9 (7), pp. e1003644. Date of Electronic Publication: 2013 Jul 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Embryonic Development/*genetics
Melanocytes/*cytology
SOXE Transcription Factors/*genetics
Stem Cells/*cytology
Animals ; Cell Differentiation/genetics ; Cell Lineage ; Hair Color/genetics ; Melanocytes/metabolism ; Mice ; Mice, Knockout ; SOXE Transcription Factors/metabolism ; Stem Cells/metabolism
Czasopismo naukowe

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