- Tytuł :
-
Insights into the biased activity of dextromethorphan and
haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis. - Autorzy :
- Źródło :
- Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2020 Dec; Vol. 98 (12), pp. 1659-1673. Date of Electronic Publication: 2020 Sep 23.
- Typ publikacji :
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms :
-
COVID-19/*drug therapy
Coronavirus Nucleocapsid Proteins/*chemistry
Dextromethorphan/*chemistryHaloperidol /*chemistry
SARS-CoV-2/*drug effects
Binding Sites/drug effects ; COVID-19/virology ; Computer Simulation ; Coronavirus Nucleocapsid Proteins/genetics ; Dextromethorphan/therapeutic use ;Haloperidol /therapeutic use ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Pandemics ; Protein Binding/drug effects ; Protein Interaction Domains and Motifs/drug effects ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity -
Czasopismo naukowe