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Wyświetlanie 1-9 z 9
Tytuł :
ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.
Autorzy :
Xu A; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Otolaryngology, Yantai Affiliated Hospital of Binzhou Medical University, 717 Jinbu Road of Muping District, Yantai, 264100, Shandong, PR China.
Shang W; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China.
Wang Y; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China.
Sun X; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Otolaryngology, Yantai Affiliated Hospital of Binzhou Medical University, 717 Jinbu Road of Muping District, Yantai, 264100, Shandong, PR China.
Zhou B; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China.
Xie Y; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China.
Xu X; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Otolaryngology, Yantai Affiliated Hospital of Binzhou Medical University, 717 Jinbu Road of Muping District, Yantai, 264100, Shandong, PR China.
Liu T; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Otolaryngology, Yantai Affiliated Hospital of Binzhou Medical University, 717 Jinbu Road of Muping District, Yantai, 264100, Shandong, PR China. Electronic address: .
Han F; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, 264003, Shandong, PR China. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2020 Jul 30; Vol. 688, pp. 108402. Date of Electronic Publication: 2020 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*pharmacology
Apoptosis/*drug effects
Citrate (si)-Synthase/*metabolism
Endoplasmic Reticulum Stress/*physiology
Oxidative Stress/*drug effects
Thioctic Acid/*pharmacology
Activating Transcription Factor 6/antagonists & inhibitors ; Animals ; Apoptosis/physiology ; Caspase 12/metabolism ; Cell Line ; Cell Proliferation/physiology ; Down-Regulation ; Endoplasmic Reticulum Stress/drug effects ; Mice ; Mitochondria/metabolism ; Models, Biological ; Oxidative Stress/physiology ; Presbycusis/physiopathology ; Reactive Oxygen Species/metabolism ; Sulfones/pharmacology ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Mangiferin exert cardioprotective and anti-apoptotic effects in heart failure induced rats.
Autorzy :
Jiang T; Department of Cardiology, The third Hospital of Jilin University, (Jilin Provincial Molecular Biology Research Centre for Precision Medicine of Major Cardiovascular Disease), Changchun, Jilin 130033, China.
Han F; Department of Anaesthesiology, The third Hospital of Jilin University, Changchun, Jilin 130033, China.
Gao G; Department of Cardiology, The third Hospital of Jilin University, (Jilin Provincial Molecular Biology Research Centre for Precision Medicine of Major Cardiovascular Disease), Changchun, Jilin 130033, China.
Liu M; Department of Cardiology, The third Hospital of Jilin University, (Jilin Provincial Molecular Biology Research Centre for Precision Medicine of Major Cardiovascular Disease), Changchun, Jilin 130033, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 May 15; Vol. 249, pp. 117476. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cardiotonic Agents/*pharmacology
Heart/*drug effects
Heart Failure/*chemically induced
Xanthones/*pharmacology
Animals ; Cardiotonic Agents/administration & dosage ; Injections, Intraperitoneal ; Isoproterenol/administration & dosage ; Isoproterenol/pharmacology ; Rats
Czasopismo naukowe
Tytuł :
PTBP1 promotes tumorigenesis by regulating apoptosis and cell cycle in colon cancer.
Autorzy :
Li X; Xinxiang Second People's Hospital, Department of Pharmacy, Xinxiang, PR China.
Han F; Army Medical University, College of Preventive Medicine, Key Laboratory of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, Chongqing, China.
Liu W; Army Medical University, College of Preventive Medicine, Key Laboratory of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, Chongqing, China.
Shi X; Henan University, Institute of Chinese materia medica, Kaifeng, China. Electronic address: .
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Źródło :
Bulletin du cancer [Bull Cancer] 2018 Dec; Vol. 105 (12), pp. 1193-1201. Date of Electronic Publication: 2018 Oct 08.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Cell Cycle*
Colonic Neoplasms/*etiology
Heterogeneous-Nuclear Ribonucleoproteins/*physiology
Neoplasm Proteins/*physiology
Polypyrimidine Tract-Binding Protein/*physiology
Cell Enlargement ; Cell Line, Tumor ; Cell Proliferation ; Colon/metabolism ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Down-Regulation ; Female ; Gene Knockdown Techniques ; Humans ; Male ; RNA, Small Interfering ; Tissue Array Analysis ; Tumor Burden ; Up-Regulation
Czasopismo naukowe
Tytuł :
A commercial Roundup® formulation induced male germ cell apoptosis by promoting the expression of XAF1 in adult mice.
Autorzy :
Jiang X; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Zhang N; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Yin L; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Zhang WL; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Han F; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Liu WB; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Chen HQ; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Cao J; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China.
Liu JY; Institute of Toxicology, College of Preventive Medicine, Army Medical University, 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, PR China. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2018 Oct 15; Vol. 296, pp. 163-172. Date of Electronic Publication: 2018 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
F-Box Proteins/*biosynthesis
Germ Cells/*drug effects
Glycine/*analogs & derivatives
Herbicides/*toxicity
Adaptor Proteins, Signal Transducing ; Animals ; Apoptosis Regulatory Proteins ; Caspase 3/drug effects ; Cell Survival/drug effects ; Glycine/toxicity ; Inhibitor of Apoptosis Proteins/biosynthesis ; Male ; Mice ; Organ Size/drug effects ; Poly (ADP-Ribose) Polymerase-1/drug effects ; Sperm Count ; Sperm Motility/drug effects ; Spermatogenesis/drug effects ; Spermatozoa/drug effects ; Spermatozoa/ultrastructure
Czasopismo naukowe
Tytuł :
The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced β cells apoptosis via up-regulation of glutathione peroxidase 1.
Autorzy :
Yang Y; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Xie F; Department of Cardiology, Qingdao Municipal Hospital, Qingdao, China.
Qin D; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Zong C; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Han F; Department of Endocrinology, Zhangqiu People's Hospital, Jinan, China.
Pu Z; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Liu D; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Li X; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China.
Zhang Y; Department of Endocrinology, Qingdao Municipal Hospital, Qingdao, China.
Liu Y; Department of Endocrinology, Qingdao Municipal Hospital, Qingdao, China.
Wang X; Department of Cell Biology, Shandong University School of Medicine, Jinan 250012, Shandong, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2018 Jun 15; Vol. 203, pp. 225-232. Date of Electronic Publication: 2018 Apr 18.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Oxidative Stress*
Glutathione Peroxidase/*metabolism
Insulin-Secreting Cells/*pathology
Islets of Langerhans/*pathology
Nuclear Receptor Subfamily 4, Group A, Member 1/*metabolism
Animals ; Cells, Cultured ; Endoplasmic Reticulum Stress ; Glutathione Peroxidase/genetics ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Mice ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Promoter Regions, Genetic ; Reactive Oxygen Species/metabolism ; Transcriptional Activation ; Up-Regulation
Czasopismo naukowe
Tytuł :
MicroRNA-130b transcriptionally regulated by histone H3 deacetylation renders Akt ubiquitination and apoptosis resistance to 6-OHDA.
Autorzy :
Xu L; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Jia Y; Department of Nephrology, Tongji Hospital, Tongji Medical College of Huanzhong University of Science & Technology, Wuhan 430030, Hubei, China.
Yang XH; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Han F; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Zheng Y; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Ni Y; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Chen X; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Hong J; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Liu JQ; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Li Q; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China.
Sun RH; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China. Electronic address: .
Mo SJ; Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310000, Zhejiang, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2017 Jun; Vol. 1863 (6), pp. 1678-1689. Date of Electronic Publication: 2017 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Drug Resistance/*drug effects
Histones/*metabolism
MicroRNAs/*metabolism
Oxidopamine/*pharmacology
Proto-Oncogene Proteins c-akt/*metabolism
Transcription, Genetic/*drug effects
Ubiquitination/*drug effects
Acetylation/drug effects ; Animals ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
Reduced expression of citrate synthase leads to excessive superoxide formation and cell apoptosis.
Autorzy :
Cai Q; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China; Department of Neurology, University Hospital of Binzhou Medical University, 661 Second Huanghe Road, Binzhou 256603, Shandong, PR China.
Zhao M; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Liu X; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Wang X; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Nie Y; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Li P; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Liu T; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China.
Ge R; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China; Department of Neurology, University Hospital of Binzhou Medical University, 661 Second Huanghe Road, Binzhou 256603, Shandong, PR China. Electronic address: .
Han F; Key Laboratory for Genetic Hearing Disorders in Shandong, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China; Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai 264003, Shandong, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2017 Apr 01; Vol. 485 (2), pp. 388-394. Date of Electronic Publication: 2017 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Apoptosis/*genetics
Citrate (si)-Synthase/*genetics
Superoxides/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Blotting, Western ; Caspase 3/metabolism ; Citrate (si)-Synthase/metabolism ; Disease Models, Animal ; HEK293 Cells ; Hearing Loss/genetics ; Heat-Shock Proteins/metabolism ; Humans ; Membrane Potential, Mitochondrial ; Mice, Inbred A ; Mice, Knockout ; Microscopy, Fluorescence ; Mitochondria/metabolism ; Mitochondria/physiology ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Transcription Factor CHOP/metabolism
Czasopismo naukowe
Tytuł :
Nur77 inhibits oxLDL induced apoptosis of macrophages via the p38 MAPK signaling pathway.
Autorzy :
Shao Q; Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Han F; Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Peng S; Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
He B; Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2016 Mar 18; Vol. 471 (4), pp. 633-8. Date of Electronic Publication: 2016 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Atherosclerosis/*pathology
Lipoproteins, LDL/*metabolism
Macrophages/*pathology
Nuclear Receptor Subfamily 4, Group A, Member 1/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Atherosclerosis/metabolism ; Cell Line, Tumor ; Cell Survival ; Humans ; Lipoproteins, LDL/pharmacology ; Macrophages/metabolism ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Signal Transduction
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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