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Wyszukujesz frazę ""Harrington KH"" wg kryterium: Autor


Wyświetlanie 1-15 z 15
Tytuł:
Relationship between CD33 expression, splicing polymorphism, and in vitro cytotoxicity of gemtuzumab ozogamicin and the CD33/CD3 BiTE® AMG 330.
Autorzy:
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center.
Beddoe ME; Clinical Research Division, Fred Hutchinson Cancer Research Center.
Godwin CD; Hematology/Oncology Fellowship Program.
Bates OM; Clinical Research Division, Fred Hutchinson Cancer Research Center.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center.
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center.
Walter RB; Hematology/Oncology Fellowship Program .; Department of Medicine, Division of Hematology.; Department of Epidemiology, University of Washington, Seattle, WA, USA.
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Źródło:
Haematologica [Haematologica] 2019 Feb; Vol. 104 (2), pp. e59-e62. Date of Electronic Publication: 2018 Aug 16.
Typ publikacji:
Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
Gene Expression*
Polymorphism, Genetic*
Antibodies, Bispecific/*pharmacology
Antineoplastic Agents, Immunological/*pharmacology
Gemtuzumab/*pharmacology
Sialic Acid Binding Ig-like Lectin 3/*genetics
Adult ; Aged ; Cell Line, Tumor ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Sialic Acid Binding Ig-like Lectin 3/antagonists & inhibitors ; Young Adult
Raport
Tytuł:
Erratum to: High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.
Autorzy:
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Alonzo TA; Department of Biostatistics, University of Southern California, Los Angeles, CA, USA.; Children's Oncology Group, Monrovia, CA, USA.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Kentsis A; Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY, USA.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Medical College of Cornell University, New York, NY, USA.
Gerbing RB; Children's Oncology Group, Monrovia, CA, USA.
Wang YC; Children's Oncology Group, Monrovia, CA, USA.
Ries RE; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Raimondi SC; Children's Oncology Group, Monrovia, CA, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Hirsch BA; Children's Oncology Group, Monrovia, CA, USA.; Department of Laboratory Medicine and Pathology, University of Minnesota Cancer Center, Minneapolis, MN, USA.
Gamis AS; Children's Oncology Group, Monrovia, CA, USA.; Division of Hematology-Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.; Children's Oncology Group, Monrovia, CA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Walter RB; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA. .; Department of Medicine, Division of Hematology, University of Washington, Seattle, WA, USA. .; Department of Epidemiology, University of Washington, Seattle, WA, USA. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2016 Nov 30; Vol. 9 (1), pp. 133. Date of Electronic Publication: 2016 Nov 30.
Typ publikacji:
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł:
Exercise and Rehabilitation of Older Horses.
Autorzy:
McKeever KH; Department of Animal Science, Equine Science Center, School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, 84 Lipman Drive, New Brunswick, NJ 08901-8525, USA. Electronic address: .
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Źródło:
The Veterinary clinics of North America. Equine practice [Vet Clin North Am Equine Pract] 2016 Aug; Vol. 32 (2), pp. 317-32.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Aging*
Horses/*physiology
Physical Conditioning, Animal/*physiology
Animals ; Exercise Tolerance ; Veterinary Medicine
Czasopismo naukowe
Tytuł:
High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.
Autorzy:
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Alonzo TA; Department of Biostatistics, University of Southern California, Los Angeles, CA, USA.; Children's Oncology Group, Monrovia, CA, USA.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Kentsis A; Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY, USA.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Medical College of Cornell University, New York, NY, USA.
Gerbing RB; Children's Oncology Group, Monrovia, CA, USA.
Wang YC; Children's Oncology Group, Monrovia, CA, USA.
Ries RE; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.
Raimondi SC; Children's Oncology Group, Monrovia, CA, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Hirsch BA; Children's Oncology Group, Monrovia, CA, USA.; Department of Laboratory Medicine and Pathology, University of Minnesota Cancer Center, Minneapolis, MN, USA.
Gamis AS; Children's Oncology Group, Monrovia, CA, USA.; Division of Hematology-Oncology, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA.; Children's Oncology Group, Monrovia, CA, USA.; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Walter RB; Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D2-190, Seattle, WA, 98109-1024, USA. .; Department of Medicine, Division of Hematology, University of Washington, Seattle, WA, USA. .; Department of Epidemiology, University of Washington, Seattle, WA, USA. .
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Źródło:
Journal of hematology & oncology [J Hematol Oncol] 2015 Oct 20; Vol. 8, pp. 115. Date of Electronic Publication: 2015 Oct 20.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
MeSH Terms:
Aminoglycosides/*therapeutic use
Antibodies, Monoclonal, Humanized/*therapeutic use
Gene Expression Regulation, Leukemic/*drug effects
Leukemia, Myeloid/*drug therapy
Acute Disease ; Adolescent ; Adult ; Aminoglycosides/adverse effects ; Antibodies, Monoclonal, Humanized/adverse effects ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Bone Marrow/drug effects ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Child ; Child, Preschool ; Female ; Gemtuzumab ; Humans ; Infant ; Infant, Newborn ; Leukemia, Myeloid/genetics ; Leukemia, Myeloid/metabolism ; MEF2 Transcription Factors/genetics ; MEF2 Transcription Factors/metabolism ; Male ; Multivariate Analysis ; Prognosis ; Regression Analysis ; Retrospective Studies ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Factors ; Survival Analysis ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł:
The Broad Anti-AML Activity of the CD33/CD3 BiTE Antibody Construct, AMG 330, Is Impacted by Disease Stage and Risk.
Autorzy:
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
Newhall KJ; Amgen, Inc., Seattle, Washington, United States of America.
Sinclair AM; Amgen, Inc., Thousand Oaks, California, United States of America.
Frankel SR; Amgen, Inc., Rockville, Maryland, United States of America.
Kischel R; Amgen Research (Munich) GmbH, Munich, Germany.
Chen G; Amgen, Inc., Seattle, Washington, United States of America.
Walter RB; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Medicine, Division of Hematology, University of Washington, Seattle, Washington, United States of America; Department of Epidemiology, University of Washington, Seattle, Washington, United States of America.
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Źródło:
PloS one [PLoS One] 2015 Aug 25; Vol. 10 (8), pp. e0135945. Date of Electronic Publication: 2015 Aug 25 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific/*administration & dosage
Cytotoxicity, Immunologic/*drug effects
Leukemia, Myeloid, Acute/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Antibodies, Bispecific/adverse effects ; CD3 Complex/biosynthesis ; Female ; Gene Expression Regulation, Leukemic/drug effects ; Humans ; Immunophenotyping ; Leukemia, Myeloid, Acute/immunology ; Leukemia, Myeloid, Acute/pathology ; Male ; Middle Aged ; Sialic Acid Binding Ig-like Lectin 3/biosynthesis ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
T-cell ligands modulate the cytolytic activity of the CD33/CD3 BiTE antibody construct, AMG 330.
Autorzy:
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Walter RB; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Medicine, Division of Hematology, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.
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Źródło:
Blood cancer journal [Blood Cancer J] 2015 Aug 21; Vol. 5, pp. e340. Date of Electronic Publication: 2015 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Bispecific/*pharmacology
Antineoplastic Agents/*pharmacology
T-Lymphocytes/*physiology
Antibody-Dependent Cell Cytotoxicity ; CD28 Antigens/agonists ; CD28 Antigens/metabolism ; CD3 Complex/metabolism ; Drug Screening Assays, Antitumor ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Ligands ; Sialic Acid Binding Ig-like Lectin 3/metabolism ; T-Lymphocytes/drug effects ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
High expression of suppressor of cytokine signaling-2 predicts poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.
Autorzy:
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center , Seattle, WA , USA.
Ries RE
Gudgeon CJ
Harrington KH
Alonzo TA
Gerbing RB
Raimondi SC
Hirsch BA
Gamis AS
Meshinchi S
Walter RB
Pokaż więcej
Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2014 Dec; Vol. 55 (12), pp. 2817-21. Date of Electronic Publication: 2014 Mar 24.
Typ publikacji:
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
MeSH Terms:
Gene Expression*
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*mortality
Suppressor of Cytokine Signaling Proteins/*genetics
Adolescent ; Child ; Child, Preschool ; Disease Progression ; Female ; Humans ; Infant ; Infant, Newborn ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/therapy ; Male ; Neoplasm, Residual ; Pilot Projects ; Prognosis ; RNA, Messenger/genetics ; Recurrence ; Young Adult
Czasopismo naukowe
Tytuł:
Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemia.
Autorzy:
Walter RB; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA [3] Department of Epidemiology, University of Washington, Seattle, WA, USA.
Laszlo GS; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Lionberger JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Pollard JA; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pediatrics, University of Washington, Seattle, WA, USA.
Harrington KH; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Gudgeon CJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Othus M; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Rafii S; Department of Genetic Medicine, Weill Cornell Medical College, New York, NY, USA.
Meshinchi S; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pediatrics, University of Washington, Seattle, WA, USA.
Appelbaum FR; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, USA.
Bernstein ID; 1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA [2] Department of Pediatrics, University of Washington, Seattle, WA, USA.
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Źródło:
Leukemia [Leukemia] 2014 Oct; Vol. 28 (10), pp. 1969-77. Date of Electronic Publication: 2014 Mar 18.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Hematopoietic Stem Cells/*cytology
Leukemia, Myeloid, Acute/*genetics
Antigens, CD34/metabolism ; Cell Hypoxia ; Cell Separation ; Coculture Techniques ; Core Binding Factors/metabolism ; Flow Cytometry ; Hematopoietic System ; Humans ; Leukemia, Myeloid, Acute/metabolism ; Prognosis ; Receptors, Aryl Hydrocarbon/metabolism ; Sialic Acid Binding Ig-like Lectin 3/metabolism
Czasopismo naukowe
Tytuł:
Significance of expression of ITGA5 and its splice variants in acute myeloid leukemia: a report from the Children's Oncology Group.
Autorzy:
Walter RB; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington; Department of Epidemiology, University of Washington, Seattle, Washington.
Laszlo GS
Alonzo TA
Gerbing RB
Levy S
Fitzgibbon MP
Gudgeon CJ
Ries RE
Harrington KH
Raimondi SC
Hirsch BA
Gamis AS
W McIntosh M
Meshinchi S
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Źródło:
American journal of hematology [Am J Hematol] 2013 Aug; Vol. 88 (8), pp. 694-702. Date of Electronic Publication: 2013 Jun 20.
Typ publikacji:
Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Biomarkers, Tumor*/biosynthesis
Biomarkers, Tumor*/genetics
Integrin alpha5*/biosynthesis
Integrin alpha5*/genetics
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/mortality
Gene Expression Regulation, Leukemic/*genetics
RNA Splicing/*genetics
Transcriptome/*genetics
Adult ; Child ; Child, Preschool ; Disease-Free Survival ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Risk Factors ; Survival Rate
Czasopismo naukowe
Tytuł:
High expression of neutrophil elastase predicts improved survival in pediatric acute myeloid leukemia: a report from the Children's Oncology Group.
Autorzy:
Gudgeon CJ
Harrington KH
Laszlo GS
Alonzo TA
Gerbing RB
Gamis AS
Raimondi SC
Hirsch BA
Meshinchi S
Walter RB
Pokaż więcej
Źródło:
Leukemia & lymphoma [Leuk Lymphoma] 2013 Jan; Vol. 54 (1), pp. 202-4. Date of Electronic Publication: 2012 Jul 09.
Typ publikacji:
Letter
MeSH Terms:
Gene Expression*
Leukemia, Myeloid, Acute/*genetics
Leukemia, Myeloid, Acute/*mortality
Leukocyte Elastase/*genetics
Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Prognosis ; Young Adult
Opinia redakcyjna
Tytuł:
Endocrine alterations in the equine athlete: an update.
Autorzy:
McKeever KH; Equine Science Center, Department of Animal Science, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, 84 Lipman Drive, New Brunswick, NJ 08901-8525, USA.
Pokaż więcej
Źródło:
The Veterinary clinics of North America. Equine practice [Vet Clin North Am Equine Pract] 2011 Apr; Vol. 27 (1), pp. 197-218.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Endocrine Glands/*physiology
Energy Metabolism/*physiology
Homeostasis/*physiology
Horses/*metabolism
Physical Conditioning, Animal/*physiology
Animals ; Body Temperature Regulation/physiology ; Endocrine Glands/metabolism ; Female ; Horses/physiology ; Male ; Water-Electrolyte Balance/physiology
Czasopismo naukowe
Tytuł:
Overtraining syndrome in standardbred horses: new insights into the role of red blood cell hypervolaemia.
Autorzy:
McKeever KH
Pokaż więcej
Źródło:
Veterinary journal (London, England : 1997) [Vet J] 2003 May; Vol. 165 (3), pp. 190-2.
Typ publikacji:
Editorial
MeSH Terms:
Physical Conditioning, Animal*
Erythrocytes/*physiology
Horse Diseases/*etiology
Plasma Volume/*physiology
Animals ; Horse Diseases/pathology ; Horses ; Physical Endurance ; Risk Factors
Opinia redakcyjna
Tytuł:
Exercise physiology of the older horse.
Autorzy:
McKeever KH; Equine Science Center, Department of Animal Science, Cook College, Rutgers--The State University of New Jersey, 84 Lipman Drive, New Brunswick, NJ 08901-8525, USA.
Pokaż więcej
Źródło:
The Veterinary clinics of North America. Equine practice [Vet Clin North Am Equine Pract] 2002 Dec; Vol. 18 (3), pp. 469-90.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Aging/*physiology
Horses/*physiology
Physical Conditioning, Animal/*physiology
Animals ; Body Composition/physiology ; Cardiovascular Physiological Phenomena ; Exercise Tolerance ; Homeostasis/physiology ; Respiration
Czasopismo naukowe
Tytuł:
The endocrine system and the challenge of exercise.
Autorzy:
McKeever KH; Department of Animal Science, Cook College, Rutgers--The State University of New Jersey, 84 Lipman Drive, New Brunswick, NJ 08901-8525, USA.
Pokaż więcej
Źródło:
The Veterinary clinics of North America. Equine practice [Vet Clin North Am Equine Pract] 2002 Aug; Vol. 18 (2), pp. 321-53, vii.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Endocrine Glands/*physiology
Energy Metabolism/*physiology
Horses/*physiology
Physical Conditioning, Animal/*physiology
Animals ; Endocrine Glands/metabolism ; Horses/metabolism ; Paracrine Communication
Czasopismo naukowe
    Wyświetlanie 1-15 z 15

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