Autor: "Hartimath SV" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Therapy-Induced Changes in CXCR4 Expression in Tumor Xenografts Can Be Monitored Noninvasively with N-[C]Methyl-AMD3465 PET
Autorzy:: Hartimath, SV
Draghiciu, O.
Daemen, T
Nijman, H.W.
van Waarde, A.
Dierckx, R.A.J.O.
de Vries, E.F.J.; Pokaż więcej
Źródło:: Molecular Imaging and Biology. 22(4):883-890

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Skocz do pozycji: 2.

Tytuł:: Therapy-Induced Changes in CXCR4 Expression in Tumor Xenografts Can Be Monitored Noninvasively with N-[C]Methyl-AMD3465 PET.
Autorzy:: Hartimath, SV
Draghiciu, O.
Daemen, T
Nijman, H.W.
van Waarde, A.
Dierckx, R.A.J.O.
de Vries, E.F.J.
Hartimath, S V; Pokaż więcej
Temat:: FLUORODEOXYGLUCOSE F18
CXCR4 receptors
POSITRON emission tomography
XENOGRAFTS
CHEMOKINE receptors
TUMORS
Źródło:: Molecular Imaging & Biology; Aug2020, Vol. 22 Issue 4, p883-890, 8p

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Skocz do pozycji: 3.

Tytuł:: Imaging Memory T-Cells Stratifies Response to Adjuvant Metformin Combined with αPD-1 Therapy.
Autorzy:: Goggi JL; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Hartimath SV; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Khanapur S; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Ramasamy B; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Chin ZF; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Cheng P; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Chin HX; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
Hwang YY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
Robins EG; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, #B1-01, Singapore 117599, Singapore.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Oct 25; Vol. 23 (21). Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:: Journal Article
MeSH Terms:: Metformin*/pharmacology
Metformin*/therapeutic use
Diabetes Mellitus, Type 2*
Neoplasms*/drug therapy
Humans ; Memory T Cells ; Tumor Microenvironment ; Adjuvants, Immunologic/therapeutic use

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Skocz do pozycji: 4.

Tytuł:: Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response.
Autorzy:: Goggi JL; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
Khanapur S; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Ramasamy B; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Hartimath SV; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Rong TJ; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Cheng P; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Tan YX; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Yeo XY; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Jung S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Goay SSM; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Ong ST; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Hwang YY; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
Chandy KG; LKCMedicine-ICESing Ion Channel Platform, Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Singapore 636921, Singapore.
Robins EG; Institute of Bioengineering and Bioimaging (IBB), Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, #B1-01, Singapore 117599, Singapore.; Pokaż więcej
Źródło:: Cancers [Cancers (Basel)] 2022 Feb 26; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 26.
Typ publikacji:: Journal Article

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Skocz do pozycji: 5.

Tytuł:: Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model.
Autorzy:: Hartimath SV; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.
Ramasamy B; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.; Department of Pharmacology, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.
Xuan TY; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.
Rong TJ; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.
Khanapur S; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.
Cheng P; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.
Hwang YY; FACS facility, Singapore Immunology Network (SIgN), A*STAR Research Entities, Immunos, Singapore 138665, Singapore.
Robins EG; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.; Clinical Imaging Research Centre (CIRC), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.
Goggi JL; Laboratory of Radiochemistry & Molecular Imaging (LRMI), Institute of Bioengineering and Bioimaging (IBB), A*STAR Research Entities, Helios, Singapore 138667, Singapore.; Pokaż więcej
Źródło:: Pharmaceutics [Pharmaceutics] 2022 Jan 08; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 08.
Typ publikacji:: Journal Article

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Skocz do pozycji: 6.

Tytuł:: Granzyme B PET Imaging Stratifies Immune Checkpoint Inhibitor Response in Hepatocellular Carcinoma.
Autorzy:: Goggi JL; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Ramasamy B; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Tan YX; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Hartimath SV; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Tang JR; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Cheng P; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.
Msallam R; Laboratory for Translational and Molecular Imaging (LTMI), Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857.
Chacko AM; Laboratory for Translational and Molecular Imaging (LTMI), Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, 8 College Road, Singapore 169857.
Hwang YY; Singapore Immunology Network, A STAR, 8A Biomedical Grove, Immunos, Singapore 138648.
Robins EG; Institute of Bioengineering and Bioimaging, Agency for Science, Technology and Research (ASTAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667.; Clinical Imaging Research Centre, 14 Medical Drive, #B1-01, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599.; Pokaż więcej
Źródło:: Molecular imaging [Mol Imaging] 2021 Dec 09; Vol. 2021, pp. 9305277. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/diagnostic imaging
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/diagnostic imaging
Liver Neoplasms*/drug therapy
Liver Neoplasms*/pathology
Granzymes/therapeutic use ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Positron-Emission Tomography ; Tumor Microenvironment

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Skocz do pozycji: 7.

Tytuł:: An Improved Synthesis of N-(4-[ F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models.
Autorzy:: Khanapur S; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Yong FF; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Hartimath SV; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Jiang L; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Ramasamy B; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Cheng P; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Narayanaswamy P; Sciex, R&D, Blk 33, #04-06 Marsiling Industrial Estate Road 3 Woodlands Central Industrial Estate, Singapore 739256, Singapore.
Goggi JL; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.
Robins EG; Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), 11 Biopolis Way, #01-02 Helios, Singapore 138667, Singapore.; Clinical Imaging Research Centre, 14 Medical Drive, #B01-01 Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 19; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 19.
Typ publikacji:: Journal Article
MeSH Terms:: Colonic Neoplasms*/diagnostic imaging
Colonic Neoplasms*/metabolism
Colonic Neoplasms*/pathology
Interleukin-2*/chemistry
Interleukin-2*/pharmacology
Neoplasms, Experimental*/diagnostic imaging
Neoplasms, Experimental*/metabolism
Positron-Emission Tomography*
Radiopharmaceuticals*/chemistry
Radiopharmaceuticals*/pharmacology
Lymphocytes, Tumor-Infiltrating/*metabolism
T-Lymphocytes/*metabolism
Animals ; Cell Line, Tumor ; Lymphocytes, Tumor-Infiltrating/pathology ; Mice ; Mice, Inbred BALB C ; T-Lymphocytes/pathology ; Tumor Microenvironment/drug effects

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Skocz do pozycji: 8.

Tytuł:: Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer.
Autorzy:: Solomon VR; Department of Medical Imaging, RUH Saskatoon, University of Saskatchewan, College of Medicine, 103 Hospital Dr., Saskatoon, SK, S7N 0W8, Canada.
Alizadeh E; Department of Medical Imaging, RUH Saskatoon, University of Saskatchewan, College of Medicine, 103 Hospital Dr., Saskatoon, SK, S7N 0W8, Canada.
Bernhard W; Department of Pathology and Laboratory Medicine, University of Saskatchewan, College of Medicine, Saskatoon, SK, Canada.
Makhlouf A; Department of Medical Imaging, RUH Saskatoon, University of Saskatchewan, College of Medicine, 103 Hospital Dr., Saskatoon, SK, S7N 0W8, Canada.; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo, 12411, Egypt.
Hartimath SV; Department of Medical Imaging, RUH Saskatoon, University of Saskatchewan, College of Medicine, 103 Hospital Dr., Saskatoon, SK, S7N 0W8, Canada.
Hill W; Department of Pathology and Laboratory Medicine, University of Saskatchewan, College of Medicine, Saskatoon, SK, Canada.
El-Sayed A; Department of Pathology and Laboratory Medicine, University of Saskatchewan, College of Medicine, Saskatoon, SK, Canada.
Barreto K; Department of Pathology and Laboratory Medicine, University of Saskatchewan, College of Medicine, Saskatoon, SK, Canada.
Geyer CR; Department of Pathology and Laboratory Medicine, University of Saskatchewan, College of Medicine, Saskatoon, SK, Canada.
Fonge H; Department of Medical Imaging, RUH Saskatoon, University of Saskatchewan, College of Medicine, 103 Hospital Dr., Saskatoon, SK, S7N 0W8, Canada. .; Department of Medical Imaging, Royal University Hospital Saskatoon, Saskatoon, SK, Canada. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Oct 29; Vol. 10 (1), pp. 18549. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibodies, Monoclonal, Humanized/*pharmacology
Immunoconjugates/*pharmacology
Neoplasms/*drug therapy
Neoplasms/*metabolism
Receptor, IGF Type 1/*metabolism
Animals ; Cell Line, Tumor ; Female ; Humans ; Insulin/metabolism ; MCF-7 Cells ; Mice, Nude

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Skocz do pozycji: 9.

Tytuł:: Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson's disease.
Autorzy:: Goggi JL; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Qiu L; Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
Liao MC; Bioprocessing Technology Institute, A*STAR, 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Khanapur S; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Jiang L; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Boominathan R; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Hartimath SV; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Cheng P; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Yong FF; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Soh V; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Deng X; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Lin YM; Bioprocessing Technology Institute, A*STAR, 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Haslop A; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Tan PW; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Zeng X; Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
Lee JWL; Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
Zhang Z; Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
Sadasivam P; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore.
Tan EK; Research Department, National Neuroscience Institute, SGH Campus, Singapore, 169856, Singapore.; Department of Neurology, National Neuroscience Institute, SGH Campus, Singapore, 169856, Singapore.; Neuroscience & Behavioural Disorders Program, DUKE-NUS Graduate Medical School, Singapore, 169857, Singapore.
Luthra SK; GE Healthcare Life Sciences, White Lion Rd., Little Chalfont, Amersham, HP7 9LL, UK.
Shingleton WD; GE Healthcare Life Sciences, White Lion Rd., Little Chalfont, Amersham, HP7 9LL, UK.
Oh SKW; Bioprocessing Technology Institute, A*STAR, 20 Biopolis Way, #06-01 Centros, Singapore, 138668, Singapore.
Zeng L; Neural Stem Cell Research Lab, Research Department, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. Li_.; Neuroscience & Behavioural Disorders Program, DUKE-NUS Graduate Medical School, Singapore, 169857, Singapore. Li_.; Lee Kong Chian School of Medicine, Novena Campus, 11 Mandalay Road, Singapore, 308232, Singapore. Li_.
Robins EG; Singapore Bioimaging Consortium, A*STAR, 11 Biopolis Way, #01-02 HELIOS, Singapore, 138667, Singapore. Edward_.; Clinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. Edward_.; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2020 Aug 08; Vol. 11 (1), pp. 347. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Dopaminergic Neurons*
Parkinson Disease*/diagnostic imaging
Parkinson Disease*/therapy
Positron Emission Tomography Computed Tomography*
Animals ; Disease Models, Animal ; Dopamine Plasma Membrane Transport Proteins ; Female ; Neuroimaging ; Oxidopamine ; Rats

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