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Tytuł:
Task design for crowdsourced glioma cell annotation in microscopy images.
Autorzy:
Schwarze S; Department of Neuropathology, Institute for Pathology, Hannover Medical School, Hannover, Germany.
Schaadt NS; Department of Neuropathology, Institute for Pathology, Hannover Medical School, Hannover, Germany.
Sobotta VMG; Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Braunschweig, Germany.
Spicher N; Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Braunschweig, Germany.
Skripuletz T; Department of Neurology, Hannover Medical School, Hannover, Germany.
Esmaeilzadeh M; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Krauss JK; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Hartmann C; Department of Neuropathology, Institute for Pathology, Hannover Medical School, Hannover, Germany.
Deserno TM; Peter L. Reichertz Institute for Medical Informatics of TU Braunschweig and Hannover Medical School, Braunschweig, Germany.
Feuerhake F; Department of Neuropathology, Institute for Pathology, Hannover Medical School, Hannover, Germany. .; Institute of Neuropathology, University Clinic Freiburg, Freiburg, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 23; Vol. 14 (1), pp. 1965. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Crowdsourcing*
Glioma*
Glioblastoma*
Humans ; Microscopy, Fluorescence ; Biomarkers, Tumor ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families.
Autorzy:
Weber CAM; Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Krönke N; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Volk V; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Auber B; Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Förster A; Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Trost D; Laboratoire CERBA, Saint-Ouen l'Aumône, France.
Geffers R; Genome Analytics Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Esmaeilzadeh M; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Lalk M; Department of Neurosurgery, KRH Klinikum Nordstadt, Hannover, Germany.
Nabavi A; Department of Neurosurgery, KRH Klinikum Nordstadt, Hannover, Germany.
Samii A; Department of Neurosurgery, International Neuroscience Institute, Hannover, Germany.
Krauss JK; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Feuerhake F; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.; Institute for Neuropathology, University Clinic Freiburg, Freiburg, Germany.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Wiese B; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.; Department of Neurology, Henriettenstift, Diakovere Krankenhaus gGmbH, Hannover, Germany.
Brand F; Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Weber RG; Department of Human Genetics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Nov 21; Vol. 11 (1), pp. 184. Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*
Glioma*/genetics
Humans ; DNA Polymerase II/genetics ; Catalytic Domain ; Germ-Line Mutation ; DNA ; DNA Polymerase III/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
EMP3 sustains oncogenic EGFR/CDK2 signaling by restricting receptor degradation in glioblastoma.
Autorzy:
Martija AA; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Krauß A; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.; Faculty of Medicine, Heidelberg University, Heidelberg, Germany.
Bächle N; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.; Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Doth L; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Christians A; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.; Canopy Biosciences, Bruker Nano Group, Hannover, Germany.
Krunic D; Light Microscopy Facility, DKFZ, Heidelberg, Germany.
Schneider M; Proteomics Core Facility, DKFZ, Heidelberg, Germany.
Helm D; Proteomics Core Facility, DKFZ, Heidelberg, Germany.
Will R; Cellular Tools Core Facility, DKFZ, Heidelberg, Germany.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Herold-Mende C; Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
von Deimling A; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
Pusch S; Clinical Cooperation Unit (CCU) Neuropathology, German Cancer Research Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. .; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Nov 07; Vol. 11 (1), pp. 177. Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epidermal Growth Factor*/pharmacology
Glioblastoma*/pathology
Humans ; Signal Transduction ; ErbB Receptors/metabolism ; Cell Proliferation ; Cell Line, Tumor ; Cyclin-Dependent Kinase 2/metabolism ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; GTPase-Activating Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differences in the Time Course of Recovery from Brain and Liver Dysfunction in Conventional Long-Term Treatment of Wilson Disease.
Autorzy:
Hefter H; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Kruschel TS; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Novak M; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Rosenthal D; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Luedde T; Departments of Gastroenterology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Meuth SG; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Albrecht P; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.; Department of Neurology, Kliniken Maria Hilf GmbH Mönchengladbach, 41063 Mönchengladbach, Germany.
Hartmann CJ; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.
Samadzadeh S; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, D-40225 Düsseldorf, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Unverstät zu Berlin, Experimental and Clinical Research Center, 13125 Berlin, Germany.; Department of Regional Health Research and Molecular Medicine, University of Southern Denmark, 5230 Odense, Denmark.; Department of Neurology, Slagelse Hospital, 4200 Slagelse, Denmark.
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Źródło:
Journal of clinical medicine [J Clin Med] 2023 Jul 24; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1.
Autorzy:
Thüring EM; Institute-associated Research Group 'Cell adhesion and cell polarity', Institute of Medical Biochemistry, ZMBE, University of Münster, Münster, Germany.
Hartmann C; Institute-associated Research Group 'Cell adhesion and cell polarity', Institute of Medical Biochemistry, ZMBE, University of Münster, Münster, Germany.
Maddumage JC; Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.
Javorsky A; Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.
Michels BE; Institute-associated Research Group 'Cell adhesion and cell polarity', Institute of Medical Biochemistry, ZMBE, University of Münster, Münster, Germany.
Gerke V; Institute of Medical Biochemistry, ZMBE, University of Münster, Münster, Germany.
Banks L; International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
Humbert PO; Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.
Kvansakul M; Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia. .
Ebnet K; Institute-associated Research Group 'Cell adhesion and cell polarity', Institute of Medical Biochemistry, ZMBE, University of Münster, Münster, Germany. .; Cells-in-Motion Interfaculty Center, University of Münster, Münster, Germany. .
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Źródło:
Communications biology [Commun Biol] 2023 Jul 10; Vol. 6 (1), pp. 702. Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Platelet Glycoprotein GPIb-IX Complex*
Epithelial Cells*
Membranes ; Cell Adhesion
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anaplastic ganglioglioma-A diagnosis comprising several distinct tumour types.
Autorzy:
Reinhardt A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pfister K; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Pathology, Kantonsspital Winterthur, Winterthur, Switzerland.
Schrimpf D; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stichel D; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sahm F; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Reuss DE; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Capper D; Department of Neuropathology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Wefers AK; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ebrahimi A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, University of Bonn, Bonn, Germany.
Sill M; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Felsberg J; Institute of Neuropathology, Heinrich Heine University, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany.
Reifenberger G; Institute of Neuropathology, Heinrich Heine University, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany.; German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Becker A; Department of Neuropathology, University of Bonn, Bonn, Germany.
Prinz M; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.
Staszewski O; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.
Hartmann C; Department of Neuropathology, Hannover Medical School, Hanover, Germany.
Schittenhelm J; Institute of Pathology and Neuropathology, Comprehensive Cancer Center Tübingen, University Tübingen, Tübingen, Germany.
Gramatzki D; Department of Neurology, University Hospital and University Zürich, Zürich, Switzerland.
Weller M; Department of Neurology, University Hospital and University Zürich, Zürich, Switzerland.
Olar A; NOMIX Laboratories, Denver, Colorado, USA.
Rushing EJ; Institute of Neuropathology, University Hospital Zürich (USZ), Zürich, Switzerland.
Bergmann M; Institute of Neuropathology, Center for Pathology, Klinikum Bremen Mitte, Bremen, Germany.
Farrell MA; Department of Neuropathology, Beaumont Hospital, Dublin, Ireland.
Blümcke I; Department of Neuropathology, University Hospital Erlangen, Member of EpiCARE ERN, Erlangen, Germany.
Coras R; Department of Neuropathology, University Hospital Erlangen, Member of EpiCARE ERN, Erlangen, Germany.
Beckervordersandforth J; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Kim SH; Department of Pathology, Yonsei University College of Medicine, Seoul, South Korea.
Rogerio F; Department of Pathology, University of Campinas (UNICAMP), Campinas, Brazil.
Dimova PS; Epilepsy Surgery Center, Department of Neurosurgery, St. Ivan Rilski University Hospital, Sofia, Bulgaria.
Niehusmann P; Section of Neuropathology, Department of Pathology, Oslo University Hospital, Oslo, Norway.
Unterberg A; Clinic for Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Platten M; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumour Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pfister SM; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Paediatric Oncology and Hematology, University Hospital Heidelberg, Heidelberg, Germany.
Wick W; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Neurology Clinic, University Hospital Heidelberg, Heidelberg, Germany.
Herold-Mende C; Division of Experimental Neurosurgery, Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
von Deimling A; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Dec; Vol. 48 (7), pp. e12847. Date of Electronic Publication: 2022 Sep 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ganglioglioma*/pathology
Glioma*/pathology
Astrocytoma*/pathology
Brain Neoplasms*/genetics
Central Nervous System Neoplasms*/pathology
Child ; Humans ; Retrospective Studies ; Isocitrate Dehydrogenase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudocholinesterase as a Biomarker for Untreated Wilson's Disease.
Autorzy:
Hefter H; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Arslan M; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.; Departments of Anesthesiology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Kruschel TS; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Novak M; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Rosenthal D; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Meuth SG; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Albrecht P; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Hartmann CJ; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Samadzadeh S; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.; Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
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Źródło:
Biomolecules [Biomolecules] 2022 Nov 30; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Butyrylcholinesterase*/blood
Butyrylcholinesterase*/urine
Hepatolenticular Degeneration*/diagnosis
Humans ; Biomarkers/blood ; Biomarkers/urine ; Ceruloplasmin/analysis ; Ceruloplasmin/urine ; ROC Curve
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cholinesterase Deficiency Syndrome-A Pitfall in the Use of Butyrylcholinesterase as a Biomarker for Wilson's Disease.
Autorzy:
Arslan M; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.; Departments of Anesthesiology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Novak M; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Rosenthal D; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Hartmann CJ; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Albrecht P; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Samadzadeh S; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Hefter H; Departments of Neurology, University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.
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Źródło:
Biomolecules [Biomolecules] 2022 Sep 30; Vol. 12 (10). Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Case Reports
MeSH Terms:
Hepatolenticular Degeneration*/diagnosis
Hepatolenticular Degeneration*/genetics
Male ; Child ; Humans ; Aged ; Child, Preschool ; Butyrylcholinesterase ; Copper/metabolism ; Biomarkers
SCR Disease Name:
Butyrylcholinesterase deficiency
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC.
Autorzy:
Hasselblatt M; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Thomas C; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Federico A; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.
Bens S; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
Hellström M; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Casar-Borota O; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.; Department of Clinical Pathology, Uppsala University Hospital, Uppsala, Sweden.
Kordes U; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg, Germany.
Neumann JE; Institute of Neuropathology, University Medical Center, Hamburg, Germany.; Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Dottermusch M; Institute of Neuropathology, University Medical Center, Hamburg, Germany.; Center for Molecular Neurobiology Hamburg (ZMNH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Rodriguez FJ; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Lo AC; Radiation Oncology, British Columbia Cancer and University of British Columbia, Vancouver, Canada.
Cheng S; Division of Hematology, Oncology and BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
Hendson G; Department of Pathology, BC Women and Children's Hospital, Vancouver, Canada.
Hukin J; Division of Hematology, Oncology and BMT, Department of Pediatrics, University of British Columbia, Vancouver, Canada.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Koch A; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Capper D; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Siebert R; Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany.
Paulus W; Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Nemes K; Pediatric and Adolescent Medicine, Swabian Childrens' Cancer Center, University Childrens' Hospital Medical Center Augsburg and EU-RHAB Registry, Augsburg, Germany.
Johann PD; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Pediatric and Adolescent Medicine, Swabian Childrens' Cancer Center, University Childrens' Hospital Medical Center Augsburg and EU-RHAB Registry, Augsburg, Germany.
Frühwald MC; Pediatric and Adolescent Medicine, Swabian Childrens' Cancer Center, University Childrens' Hospital Medical Center Augsburg and EU-RHAB Registry, Augsburg, Germany.
Kool M; Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany.; Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2022 Jun; Vol. 48 (4), pp. e12797. Date of Electronic Publication: 2022 Feb 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Rhabdoid Tumor*/pathology
Teratoma*
Child ; Epigenesis, Genetic ; Humans ; SMARCB1 Protein/genetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preliminary application of native Nephila edulis spider silk and fibrin implant causes granulomatous foreign body reaction in vivo in rat's spinal cord.
Autorzy:
Koop F; Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
Strauß S; Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
Peck CT; Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
Aper T; Cardiac, Thoracic, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Wilhelmi M; Cardiac, Thoracic, and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Hartmann C; Department of Neuropathology, Hannover Medical School, Hannover, Germany.
Hegermann J; Research Core Unit Electron Microscopy and Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Schipke J; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Vogt PM; Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
Bucan V; Department of Plastic, Aesthetic, Hand & Reconstructive Surgery, Hannover Medical School, Hannover, Germany.
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Źródło:
PloS one [PLoS One] 2022 Mar 14; Vol. 17 (3), pp. e0264486. Date of Electronic Publication: 2022 Mar 14 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Spinal Cord Injuries*/therapy
Spinal Cord Regeneration*
Animals ; Fibrin ; Foreign-Body Reaction ; Nerve Regeneration ; Rats ; Rats, Wistar ; Silk ; Spinal Cord ; Tissue Scaffolds
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differences in the MRI Signature and ADC Values of Diffuse Midline Gliomas with H3 K27M Mutation Compared to Midline Glioblastomas.
Autorzy:
Raab P; Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, 30625 Hannover, Germany.
Banan R; Department of Neuropathology, University of Heidelberg, 69120 Heidelberg, Germany.
Akbarian A; Department of Neuroradiology, INI-Hannover, 30625 Hannover, Germany.
Esmaeilzadeh M; Department of Neurosurgery, Hannover Medical School, 30625 Hannover, Germany.
Samii M; Department of Neurosurgery, INI-Hannover, 30625 Hannover, Germany.
Samii A; Department of Neurosurgery, INI-Hannover, 30625 Hannover, Germany.
Bertalanffy H; Department of Neurosurgery, INI-Hannover, 30625 Hannover, Germany.
Lehmann U; Institute of Pathology, Hannover Medical School, 30625 Hannover, Germany.
Krauss JK; Department of Neurosurgery, Hannover Medical School, 30625 Hannover, Germany.
Lanfermann H; Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, 30625 Hannover, Germany.
Hartmann C; Institute of Pathology, Hannover Medical School, 30625 Hannover, Germany.
Brüning R; Department of Radiology and Neuroradiology, Asklepios Klinik Barmbek, 22307 Hamburg, Germany.
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Źródło:
Cancers [Cancers (Basel)] 2022 Mar 09; Vol. 14 (6). Date of Electronic Publication: 2022 Mar 09.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Spatial and temporal changes of outdoor thermal stress: influence of urban land cover types.
Autorzy:
Rahman MA; Strategic Landscape Planning and Management, School of Life Sciences, Weihenstephan, Technische Universität München, Emil-Ramann-Str. 6, 85354, Freising, Germany. .
Franceschi E; Forest Growth and Yield Science, School of Life Sciences, Weihenstephan, Technische Universität München, Hans-Carl-von-Carlowitz-Platz 2, 85354, Freising, Germany.
Pattnaik N; Strategic Landscape Planning and Management, School of Life Sciences, Weihenstephan, Technische Universität München, Emil-Ramann-Str. 6, 85354, Freising, Germany.
Moser-Reischl A; Forest Growth and Yield Science, School of Life Sciences, Weihenstephan, Technische Universität München, Hans-Carl-von-Carlowitz-Platz 2, 85354, Freising, Germany.
Hartmann C; Institute of Geography and Geology, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.
Paeth H; Institute of Geography and Geology, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany.
Pretzsch H; Forest Growth and Yield Science, School of Life Sciences, Weihenstephan, Technische Universität München, Hans-Carl-von-Carlowitz-Platz 2, 85354, Freising, Germany.
Rötzer T; Forest Growth and Yield Science, School of Life Sciences, Weihenstephan, Technische Universität München, Hans-Carl-von-Carlowitz-Platz 2, 85354, Freising, Germany.
Pauleit S; Strategic Landscape Planning and Management, School of Life Sciences, Weihenstephan, Technische Universität München, Emil-Ramann-Str. 6, 85354, Freising, Germany.
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 13; Vol. 12 (1), pp. 671. Date of Electronic Publication: 2022 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The prognostic significance of clinicopathological features in meningiomas: Microscopic brain invasion can predict patient outcome in otherwise benign meningiomas.
Autorzy:
Banan R; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Abbetmeier-Basse M; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Hong B; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Dumitru CA; Department of Neurosurgery, Otto-von-Guericke University, Magdeburg, Germany.
Sahm F; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Institute (DKFZ), Heidelberg, Germany.
Nakamura M; Department of Neurosurgery, Krankenhaus Köln Merheim, Kliniken der Stadt Köln gGmbH, University of Witten/Herdecke, Köln, Germany.
Krauss JK; Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2021 Oct; Vol. 47 (6), pp. 724-735. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*pathology
Brain Neoplasms/*pathology
Meningeal Neoplasms/*pathology
Meningioma/*pathology
Adult ; Aged ; Female ; Humans ; Male ; Meningeal Neoplasms/diagnosis ; Meningioma/diagnosis ; Middle Aged ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Molecular characterisation of sporadic endolymphatic sac tumours and comparison to von Hippel-Lindau disease-related tumours.
Autorzy:
Schweizer L; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Thierfelder F; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Thomas C; Department of Neuropathology, University Hospital Münster, Münster, Germany.
Soschinski P; Department of Neuropathology, University Hospital Münster, Münster, Germany.
Kim HY; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jödicke R; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Woltering N; Department of Neuropathology, University Hospital Münster, Münster, Germany.
Förster A; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Teichmann D; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Siewert C; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Klein K; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Schmid S; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Nunninger M; Department of Radiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Thomale UW; Department of Neurosurgery, Division Pediatric Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Onken J; Department of Neurosurgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Mühleisen H; SYNLAB Labor für Pathologie Mutlangen, Mutlangen, Germany.
Schittenhelm J; Department of Neuropathology, Institute of Pathology and Neuropathology, University of Tübingen, Tübingen, Germany.
Tatagiba M; Department of Neurosurgery, University of Tübingen, Tübingen, Germany.
von Deimling A; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Reuss DE; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
Solomon DA; Division of Neuropathology, Department of Pathology, University of California, San Francisco, California, USA.
Heppner FL; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Cluster of Excellence, NeuroCure, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.
Koch A; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Hartmann C; Department of Neuropathology, Hannover Medical School, Hannover, Germany.
Staszewski O; Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Capper D; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło:
Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2021 Oct; Vol. 47 (6), pp. 756-767. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ear Neoplasms/*pathology
Endolymphatic Sac/*pathology
Tumor Suppressor Proteins/*metabolism
von Hippel-Lindau Disease/*pathology
Adult ; Ear Neoplasms/complications ; Ear Neoplasms/genetics ; Endolymphatic Sac/metabolism ; Humans ; Middle Aged ; Mutation/genetics ; Risk ; Tumor Suppressor Proteins/genetics ; von Hippel-Lindau Disease/complications ; von Hippel-Lindau Disease/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Diffuse midline gliomas, H3 K27M-mutant are associated with less peritumoral edema and contrast enhancement in comparison to glioblastomas, H3 K27M-wildtype of midline structures.
Autorzy:
Banan R; Department of Neuropathology, University of Heidelberg, Heidelberg, Germany.; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Akbarian A; Department of Neuroradiology, INI-Hannover, Hannover, Germany.
Samii M; Department of Neurosurgery, INI-Hannover, Hannover, Germany.
Samii A; Department of Neurosurgery, INI-Hannover, Hannover, Germany.
Bertalanffy H; Department of Neurosurgery, INI-Hannover, Hannover, Germany.
Lehmann U; Institute of Pathology, Hannover Medical School, Hannover, Germany.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Brüning R; Radiology and Neuroradiology, Asklepios Klinik Barmbek, Hamburg, Germany.
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Źródło:
PloS one [PLoS One] 2021 Aug 04; Vol. 16 (8), pp. e0249647. Date of Electronic Publication: 2021 Aug 04 (Print Publication: 2021).
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Brain Neoplasms/*diagnostic imaging
Glioblastoma/*diagnostic imaging
Glioma/*diagnostic imaging
Adolescent ; Adult ; Aged ; Brain Neoplasms/classification ; Brain Neoplasms/pathology ; Brain Stem Neoplasms/classification ; Brain Stem Neoplasms/diagnostic imaging ; Brain Stem Neoplasms/pathology ; Child ; Child, Preschool ; Female ; Glioblastoma/classification ; Glioblastoma/pathology ; Glioma/classification ; Glioma/pathology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neuroimaging ; Retrospective Studies ; Spinal Cord Neoplasms/classification ; Spinal Cord Neoplasms/diagnostic imaging ; Spinal Cord Neoplasms/pathology ; Thalamus/diagnostic imaging ; Thalamus/pathology ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria.
Autorzy:
Hartmann C; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Schwietzer YA; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Kummer D; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Interdisciplinary Clinical Research Center (IZKF), University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Kirschnick N; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Hoppe E; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Thüring EM; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Glaesner-Ebnet M; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Brinkmann F; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Gerke V; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany.
Reuter S; Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, 48149, Münster, Germany.
Nakayama M; Laboratory for Cell Polarity and Organogenesis, Max-Planck-Institute for Heart and Lung Research, 61231, Bad Nauheim, Germany.
Ebnet K; Institute-Associated Research Group 'Cell adhesion and cell polarity', University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany. .; Institute of Medical Biochemistry, ZMBE, University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany. .; Interdisciplinary Clinical Research Center (IZKF), University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany. .; Cells-in-Motion Cluster of Excellence (EXC 1003 - CiM), University of Münster, 48419, Münster, Germany. .
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2020 Apr 17; Vol. 21 (1), pp. 30. Date of Electronic Publication: 2020 Apr 17.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial Cells/*metabolism
Membrane Glycoproteins/*metabolism
Membrane Proteins/*metabolism
Mitochondria/*metabolism
Mitochondrial Membranes/*metabolism
Cell Adhesion/genetics ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cytoplasm/metabolism ; Glycosylation ; Humans ; Junctional Adhesion Molecules/genetics ; Junctional Adhesion Molecules/metabolism ; Membrane Glycoproteins/genetics ; Membrane Proteins/genetics ; Mitochondria/genetics ; PDZ Domains/genetics ; Protein Binding
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma.
Autorzy:
Behling F; Institute of Neuropathology, University Medical Center Goettingen, Goettingen, Germany.; Department of Neurosurgery, University Hospital Tuebingen, Tuebingen, Germany.; Center for CNS Tumors, Comprehensive Cancer Center Tuebingen-Stuttgart, University Hospital Tuebingen, Tuebingen, Germany.
Barrantes-Freer A; Institute of Neuropathology, University Medical Center Goettingen, Goettingen, Germany.; Department of Neuropathology, Leipzig University Medicine, Leipzig, Germany.
Behnes CL; Institute of Pathology, University Medical Center Goettingen, Goettingen, Germany.
Stockhammer F; Department of Neurosurgery, University Medical Center Goettingen, Goettingen, Germany.
Rohde V; Department of Neurosurgery, University Medical Center Goettingen, Goettingen, Germany.
Adel-Horowski A; Department of Neurosurgery, University Medical Center Goettingen, Goettingen, Germany.
Rodríguez-Villagra OA; Neuroscience Research Center, University of Costa Rica, San José, Costa Rica.; Institute for Psychological Research, University of Costa Rica, San José, Costa Rica.
Barboza MA; Neurosciences Department, Hospital Dr. Rafael A. Calderón Guardia, CCSS, University of Costa Rica, San José, Costa Rica.
Brück W; Institute of Neuropathology, University Medical Center Goettingen, Goettingen, Germany.
Lehmann U; Institute of Pathology, Hannover Medical School, Hannover, Germany.
Stadelmann C; Institute of Neuropathology, University Medical Center Goettingen, Goettingen, Germany.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover, Germany.
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Źródło:
PloS one [PLoS One] 2020 Mar 11; Vol. 15 (3), pp. e0229274. Date of Electronic Publication: 2020 Mar 11 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor/*metabolism
Brain Neoplasms/*genetics
Brain Neoplasms/*mortality
Glioblastoma/*genetics
Glioblastoma/*mortality
Isocitrate Dehydrogenase/*genetics
Adult ; Aged ; Aged, 80 and over ; Aquaporin 4/genetics ; Aquaporin 4/metabolism ; Biomarkers, Tumor/genetics ; Brain Neoplasms/therapy ; Female ; Glioblastoma/therapy ; Humans ; Male ; Middle Aged ; Mutation ; Neoplasm Recurrence, Local/diagnosis ; Nestin/genetics ; Nestin/metabolism ; Nogo Proteins/genetics ; Nogo Proteins/metabolism ; Oligodendrocyte Transcription Factor 2/genetics ; Oligodendrocyte Transcription Factor 2/metabolism ; Prognosis ; Promoter Regions, Genetic ; Retrospective Studies ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma.
Autorzy:
Kim EL; Clinic for Neurosurgery, Laboratory of Experimental Neurooncology, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Sorokin M; Institute of Personalized Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia.; Omicsway Corp., 340 S Lemon Ave, 6040, Walnut, CA 91789, USA.
Kantelhardt SR; Clinic for Neurosurgery, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Kalasauskas D; Clinic for Neurosurgery, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Sprang B; Clinic for Neurosurgery, Laboratory of Experimental Neurooncology, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Fauss J; Clinic for Neurosurgery, Laboratory of Experimental Neurooncology, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Ringel F; Clinic for Neurosurgery, Johannes Gutenberg University Medical Centre, Langenbeckstrasse 1, 55124 Mainz, Germany.
Garazha A; Omicsway Corp., 340 S Lemon Ave, 6040, Walnut, CA 91789, USA.
Albert E; Institute of Personalized Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Gaifullin N; Department of Pathology, Faculty of Medicine, Lomonosov Moscow State University, 119991 Moscow, Russia.
Hartmann C; Department of Neuropathology, Institute of Pathology, Hannover Medical School, 30625 Hannover, Germany.
Naumann N; StarSEQ GmbH, Joh.-Joachim-Becher-Weg 30a, 55128 Mainz, Germany.
Bikar SE; StarSEQ GmbH, Joh.-Joachim-Becher-Weg 30a, 55128 Mainz, Germany.
Giese A; OrthoCentrum Hamburg, Hansastrasse 1, 20149 Hamburg, Germany.
Buzdin A; Institute of Personalized Medicine, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 117997 Moscow, Russia.; Oncobox Ltd., 121205 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Moscow Region, Russia.
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Źródło:
Cancers [Cancers (Basel)] 2020 Feb 24; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 24.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Meningitis gone viral: description of the echovirus wave 2013 in Germany.
Autorzy:
Graf J; Department of Neurology, University Hospital, Medical Faculty Heinrich-Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.
Hartmann CJ; Department of Neurology, Center for Movement Disorders and Neuromodulation, Medical Faculty, University Hospital, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.; Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Lehmann HC; Department of Neurology, University Hospital of Cologne, Cologne, Germany.
Otto C; Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Adams O; Institute of Virology, University Hospital, Heinrich-Heine University, Düsseldorf, Germany.
Karenfort M; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Hospital, Heinrich-Heine University, Düsseldorf, Germany.
Schneider C; Department of Neurology, University Hospital of Cologne, Cologne, Germany.
Ruprecht K; Department of Neurology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Bosse HM; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Hospital, Heinrich-Heine University, Düsseldorf, Germany.
Diedrich S; FG 15 Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch Institut, Berlin, Germany.
Böttcher S; FG 15 Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch Institut, Berlin, Germany.
Schnitzler A; Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Hartung HP; Department of Neurology, University Hospital, Medical Faculty Heinrich-Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.
Aktas O; Department of Neurology, University Hospital, Medical Faculty Heinrich-Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.
Albrecht P; Department of Neurology, University Hospital, Medical Faculty Heinrich-Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2019 Nov 29; Vol. 19 (1), pp. 1010. Date of Electronic Publication: 2019 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Enterovirus Infections/*diagnosis
Meningitis, Viral/*diagnosis
Adolescent ; Adult ; Child ; Child, Preschool ; Enterovirus B, Human/isolation & purification ; Enterovirus Infections/epidemiology ; Enterovirus Infections/virology ; Female ; Germany/epidemiology ; Herpesvirus 2, Human/isolation & purification ; Herpesvirus 3, Human/isolation & purification ; Humans ; Length of Stay ; Male ; Meningitis, Viral/epidemiology ; Meningitis, Viral/virology ; Middle Aged ; Seasons ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities.
Autorzy:
Reinhardt A; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Stichel D; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Schrimpf D; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Koelsche C; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of General Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Wefers AK; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ebrahimi A; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sievers P; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Huang K; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Casalini MB; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Fernández-Klett F; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Suwala A; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Weller M; Department of Neurology, University Hospital and University of Zuerich, Zuerich, Switzerland.
Gramatzki D; Department of Neurology, University Hospital and University of Zuerich, Zuerich, Switzerland.
Felsberg J; Institute for Neuropathology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany.
Reifenberger G; Institute for Neuropathology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany.; German Cancer Consortium (DKTK), partner site Essen/Duesseldorf, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Becker A; Department of Neuropathology of the University of Bonn, Bonn, Germany.
Hans VH; Institute for Neuropathology of the University of Essen, Essen, Germany.
Prinz M; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Staszewski O; Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany.; Berta-Ottenstein-Programme for Advanced Clinician Scientists, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Acker T; Institute of Neuropathology, University of Giessen, Giessen, Germany.
Dohmen H; Institute of Neuropathology, University of Giessen, Giessen, Germany.
Hartmann C; Department for Neuropathology, Institute for Pathology, Hannover Medical School, Hannover, Germany.
Paulus W; Institute of Neuropathology, University Hospital Muenster, Muenster, Germany.
Heß K; Institute of Neuropathology, University Hospital Muenster, Muenster, Germany.
Brokinkel B; Institute of Neuropathology, University Hospital Muenster, Muenster, Germany.
Schittenhelm J; Institute for Pathology and Neuropathology of the University of Tuebingen, Comprehensive Cancer Center Tuebingen, Tuebingen, Germany.
Buslei R; Institute for Pathology, Sozialstiftung Bamberg, Bamberg, Germany.; Institute for Neuropathology of the Friedrich-Alexander University of Erlangen-Nuernberg (FAU), Erlangen, Germany.
Deckert M; Department of Neuropathology, University Hospital of Cologne, Cologne, Germany.
Mawrin C; Institute for Neuropathology of the University of Magdeburg, Magdeburg, Germany.
Hewer E; Institute of Pathology, University of Bern, Bern, Switzerland.
Pohl U; Department of Cellular Pathology, Queen's Hospital, Romford, UK.
Jaunmuktane Z; Department of Molecular Neuroscience, UCL Queen Square Institute of Neurology, Queen Square, London, UK.
Brandner S; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, Queen Square, London, UK.
Unterberg A; Clinic for Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany.
Hänggi D; Clinic for Neurosurgery, University of Mannheim, Mannheim, Germany.
Platten M; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology and Hematology, University Hospital Heidelberg, Heidelberg, Germany.; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.
Wick W; Neurology Clinic, University of Heidelberg Medical Center, Heidelberg, Germany.
Herold-Mende C; Division of Experimental Neurosurgery, Department of Neurosurgery, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.
Korshunov A; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Reuss DE; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Sahm F; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jones DTW; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.; Pediatric Glioma Research Group, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
Capper D; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neuropathology, Charité - Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany.
von Deimling A; Department of Neuropathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany. .; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Oct 28; Vol. 7 (1), pp. 163. Date of Electronic Publication: 2019 Oct 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebellar Neoplasms/*diagnosis
Cerebellar Neoplasms/*metabolism
Glioblastoma/*diagnosis
Glioblastoma/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cerebellar Neoplasms/pathology ; Child ; Child, Preschool ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; ErbB Receptors/metabolism ; Female ; Glioblastoma/pathology ; Humans ; Infant ; Infant, Newborn ; Infratentorial Neoplasms/diagnosis ; Infratentorial Neoplasms/metabolism ; Infratentorial Neoplasms/pathology ; Male ; Methylation ; Middle Aged ; Retrospective Studies ; Telomerase/metabolism ; Young Adult
Czasopismo naukowe
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