Autor: "Hassanein EHM" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Edaravone and Acetovanillone Upregulate Nrf2 and PI3K/Akt/mTOR Signaling and Prevent Cyclophosphamide Cardiotoxicity in Rats
Autorzy:: Hassanein EHM
Abd El-Ghafar OAM
Ahmed MA
Sayed AM
Gad-Elrab WM
Ajarem JS
Allam AA
Mahmoud AM; Pokaż więcej
Temat:: chemotherapy
acetovanillone
edaravone
oxidative stress
cardiotoxicity
nrf2
mtor.
Therapeutics. Pharmacology
RM1-950
Źródło:: Drug Design, Development and Therapy, Vol Volume 14, Pp 5275-5288 (2020)
Opis pliku:: electronic resource
Relacje:: https://www.dovepress.com/edaravone-and-acetovanillone-upregulate-nrf2-and-pi3kaktmtor-signaling-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881
Dostęp URL:: https://doaj.org/article/ebd3b02ea4ab4973a76e1328627ada7b Link otwiera się w nowym oknie

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Skocz do pozycji: 2.

Tytuł:: Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT Pathways with Rebamipide Attenuates Acetic Acid-Induced Colitis in Rats.
Autorzy:: Abdel-Fattah MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
Hassanein EHM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt.
Sayed AM; Biochemistry Laboratory, Chemistry Department, Faculty of Science, Assiut University, Assiut 71515, Egypt.
Alsufyani SE; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
El-Sheikh AAK; Basic Health Sciences Department, College of Medicine, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Arab HH; Department of Pharmacology and Toxicology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Mohamed WR; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.; Pokaż więcej
Źródło:: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Apr 02; Vol. 16 (4). Date of Electronic Publication: 2023 Apr 02.
Typ publikacji:: Journal Article

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Skocz do pozycji: 3.

Tytuł:: Acetovanillone augmented the cardioprotective effect of carvedilol against cadmium-induced heart injury via suppression of oxidative stress and inflammation signaling pathways.
Autorzy:: Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt.
Bakr AG; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt.
El-Shoura EAM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt.
Ahmed LK; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Girls), Al-Azhar University, Assiut, Egypt.
Ali FEM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt. .; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, 71524, Egypt. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Mar 31; Vol. 13 (1), pp. 5278. Date of Electronic Publication: 2023 Mar 31.
Typ publikacji:: Journal Article
MeSH Terms:: Cadmium*/toxicity
Heart Injuries*
Rats ; Animals ; Carvedilol/pharmacology ; NF-kappa B/metabolism ; Sirtuin 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Toll-Like Receptor 4/metabolism ; Oxidative Stress ; Signal Transduction ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; NADPH Oxidases/metabolism

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Skocz do pozycji: 4.

Tytuł:: Azithromycin Mitigates Cisplatin-Induced Lung Oxidative Stress, Inflammation and Necroptosis by Upregulating SIRT1, PPARγ, and Nrf2/HO-1 Signaling.
Autorzy:: Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
Sayed GA; Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Alzoghaibi AM; College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia.
Alammar AS; Dental Department, Hail Health Cluster, Ministry of Health, Hail 55421, Saudi Arabia.
Abdel-Wahab BA; Department of Medical Pharmacology, College of Medicine, Assiut University, Assiut 71515, Egypt.; Department of Pharmacology, College of Pharmacy, Najran University, Najran 55461, Saudi Arabia.
Abd El-Ghafar OAM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef 62521, Egypt.
Mahdi SE; Department of Physiology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Atwa AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Alzoghaibi MA; Physiology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia.
Mahmoud AM; Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester M1 5GD, UK.; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.; Pokaż więcej
Źródło:: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 Dec 29; Vol. 16 (1). Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:: Journal Article

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Skocz do pozycji: 5.

Tytuł:: The antimicrobial, antibiofilm, and wound healing properties of ethyl acetate crude extract of an endophytic fungus Paecilomyces sp. (AUMC 15510) in earthworm model.
Autorzy:: Salem SH; Fungal Physiology Laboratory, Botany and Microbiology Department, Faculty of Science, Assiut University, Assiut, Egypt.
El-Maraghy SS; Fungal Physiology Laboratory, Botany and Microbiology Department, Faculty of Science, Assiut University, Assiut, Egypt.
Abdel-Mallek AY; Mycology Laboratory, Botany and Microbiology Department, Faculty of Science, Assiut University, Assiut, Egypt.
Abdel-Rahman MAA; Plant Protection Research Institute, Agricultural Research Center, Dokki, Giza, Egypt.
Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University-Assiut Branch, Assiut, Egypt.
Al-Bedak OA; Assiut University Mycological Centre (AUMC), Assiut University, Assiut, Egypt.
El-Aziz FEAA; Department of Zoology, Faculty of Science, Assiut University, Assiut, 71516, Egypt. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2022 Nov 10; Vol. 12 (1), pp. 19239. Date of Electronic Publication: 2022 Nov 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Oligochaeta*
Paecilomyces*
Anti-Infective Agents*/pharmacology
Animals ; Humans ; Plant Extracts/pharmacology ; Anti-Bacterial Agents/pharmacology ; Microbial Sensitivity Tests ; Wound Healing ; Biofilms

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Skocz do pozycji: 6.

Tytuł:: Candesartan Attenuates Cisplatin-Induced Lung Injury by Modulating Oxidative Stress, Inflammation, and TLR-4/NF-κB, JAK1/STAT3, and Nrf2/HO-1 Signaling.
Autorzy:: Atwa AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Abd El-Ghafar OAM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef 62521, Egypt.
Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
Mahdi SE; Department of Physiology, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt.
Sayed GA; Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Cairo 11829, Egypt.
Alruhaimi RS; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Alqhtani HA; Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Alotaibi MF; Physiology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia.
Mahmoud AM; Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef 62514, Egypt.; Department of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester M1 5GD, UK.; Pokaż więcej
Źródło:: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2022 Oct 02; Vol. 15 (10). Date of Electronic Publication: 2022 Oct 02.
Typ publikacji:: Journal Article

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Skocz do pozycji: 7.

Tytuł:: The importance of natural chalcones in ischemic organ damage: Comprehensive and bioinformatic analysis review.
Autorzy:: Sayed AM; Biochemistry Laboratory, Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt.
Gohar OM; Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt.
Abd-Alhameed EK; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Ali FEM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.; Pokaż więcej
Źródło:: Journal of food biochemistry [J Food Biochem] 2022 Oct; Vol. 46 (10), pp. e14320. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Chalcone*
Chalcones*/chemistry
Chalcones*/pharmacology
Computational Biology ; Humans ; Ischemia ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Toll-Like Receptor 4/metabolism

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Skocz do pozycji: 8.

Tytuł:: Diallyl disulfide ameliorates methotrexate-induced nephropathy in rats: Molecular studies and network pharmacology analysis.
Autorzy:: Hassanein EHM; Faculty of Pharmacy, Department of Pharmacology & Toxicology, Al-Azhar University, Assiut, Egypt.
Mohamed WR; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Beni-Suef University, Beni-Suef, Egypt.
Khalaf MM; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Beni-Suef University, Beni-Suef, Egypt.
Shalkami AS; Faculty of Pharmacy, Department of Pharmacology & Toxicology, Al-Azhar University, Assiut, Egypt.
Sayed AM; Biochemistry Laboratory, Faculty of Science, Chemistry Department, Assiut University, Assiut, Egypt.
Hemeida RAM; Faculty of Pharmacy, Department of Pharmacology & Toxicology, Al-Azhar University, Assiut, Egypt.; Faculty of Pharmacy, Department of Pharmacology and Toxicology, Deraya University, Menia, Egypt.; Pokaż więcej
Źródło:: Journal of food biochemistry [J Food Biochem] 2021 Jun; Vol. 45 (6), pp. e13765. Date of Electronic Publication: 2021 May 16.
Typ publikacji:: Journal Article
MeSH Terms:: Methotrexate*/toxicity
NF-E2-Related Factor 2*
Allyl Compounds ; Animals ; Disulfides/pharmacology ; Disulfides/therapeutic use ; Humans ; NF-kappa B/genetics ; Rats

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Skocz do pozycji: 9.

Tytuł:: Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways.
Autorzy:: Abdel-Wahab BA; Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.; Department of Medical Pharmacology, College of Medicine, Assiut University, Assiut, Egypt.
Ali FEM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Alkahtani SA; Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Alshabi AM; Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Mahnashi MH; Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Hassanein EHM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2020 Oct; Vol. 42 (5), pp. 493-503. Date of Electronic Publication: 2020 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Alanine/*analogs & derivatives
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Apoptosis Regulatory Proteins/*metabolism
Chemical and Drug Induced Liver Injury/*prevention & control
Glycogen Synthase Kinase 3 beta/*metabolism
Janus Kinase 1/*metabolism
Liver/*drug effects
NF-E2-Related Factor 2/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
Quinolones/*pharmacology
STAT3 Transcription Factor/*metabolism
Transcription Factor RelA/*metabolism
bcl-2-Associated X Protein/*metabolism
Alanine/pharmacology ; Animals ; Apoptosis/drug effects ; Chemical and Drug Induced Liver Injury/enzymology ; Chemical and Drug Induced Liver Injury/etiology ; Chemical and Drug Induced Liver Injury/pathology ; Disease Models, Animal ; Liver/enzymology ; Liver/pathology ; Male ; Methotrexate ; Necrosis ; Oxidative Stress/drug effects ; Rats, Wistar ; Signal Transduction

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