Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""HeLa Cells"" wg kryterium: Temat


Tytuł :
A reporter cell line for real-time imaging of autophagy and apoptosis.
Autorzy :
Lupitha SS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Chandrasekhar L; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Varadarajan SN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Jayaprasad AG; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Chandrasekharan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Patil SN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Mini M; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Pillai PR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Santhoshkumar TR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India. Electronic address: .
Pokaż więcej
Źródło :
Toxicology letters [Toxicol Lett] 2020 Jun 15; Vol. 326, pp. 23-30. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Apoptosis/*drug effects
Autophagy/*drug effects
Cell Line, Tumor/*drug effects
Drug Evaluation, Preclinical/*methods
Genes, Reporter/*drug effects
Green Fluorescent Proteins/*drug effects
HeLa Cells/*drug effects
Apoptosis/physiology ; Autophagy/physiology ; Cell Line, Tumor/physiology ; Genes, Reporter/physiology ; Green Fluorescent Proteins/physiology ; HeLa Cells/physiology ; Humans
Czasopismo naukowe
Tytuł :
HeLa-CCL2 cell heterogeneity studied by single-cell DNA and RNA sequencing.
Autorzy :
Hu WE; Academy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing, China.; Biomedical Pioneering Innovation Center (BIOPIC), and State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.
Zhang X; Biomedical Pioneering Innovation Center (BIOPIC), and State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.
Guo QF; Biomedical Pioneering Innovation Center (BIOPIC), and State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.
Yang JW; Biomedical Pioneering Innovation Center (BIOPIC), and State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.
Yang Y; Clinical Research Center, Guizhou Medical University Hospital, Guiyang, China.
Wei SC; Academy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing, China.
Su XD; Biomedical Pioneering Innovation Center (BIOPIC), and State Key Laboratory of Protein and Plant Gene Research, Peking University, Beijing, China.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2019 Dec 02; Vol. 14 (12), pp. e0225466. Date of Electronic Publication: 2019 Dec 02 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
DNA Copy Number Variations*
Genetic Heterogeneity*
HeLa Cells*
Transcriptome/*genetics
Cell Culture Techniques ; Chemokine CCL2/metabolism ; Gene Expression Profiling ; Genome, Human ; Humans ; Karyotyping ; Sequence Analysis, RNA ; Single-Cell Analysis ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Antiproliferative and apoptogenic effects of Cassia fistula L. n-hexane fraction against human cervical cancer (HeLa) cells.
Autorzy :
Kaur S; Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.; Post Graduate Department of Botany, Khalsa College, Amritsar, India.
Pandit K; Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Chandel M; Post Graduate Department of Botany, Khalsa College, Amritsar, India.
Kaur S; Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India. .
Pokaż więcej
Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Sep; Vol. 27 (25), pp. 32017-32033. Date of Electronic Publication: 2020 Jun 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Springer Country of Publication: Germany NLM ID: 9441769 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1614-7499 (Electronic) Linking ISSN: 09441344 NLM ISO Abbreviation: Environ Sci Pollut Res Int Subsets: MEDLINE
MeSH Terms :
Cassia*
Uterine Cervical Neoplasms*
Apoptosis ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Cell Proliferation ; Female ; HeLa Cells ; Hexanes ; Humans ; Membrane Potential, Mitochondrial
Czasopismo naukowe
Tytuł :
A New Ciprofloxacin-derivative Inhibits Proliferation and Suppresses the Migration Ability of HeLa Cells.
Autorzy :
Fathy M; Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.
Sun S; Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Zhao QL; Department of Radiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan .
Abdel-Aziz M; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.
Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.
Awale S; Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Nikaido T; Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Pokaż więcej
Źródło :
Anticancer research [Anticancer Res] 2020 Sep; Vol. 40 (9), pp. 5025-5033.
Typ publikacji :
Journal Article
Journal Info :
Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Ciprofloxacin/*analogs & derivatives
Ciprofloxacin/*pharmacology
Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Ciprofloxacin/chemistry ; Dose-Response Relationship, Drug ; HeLa Cells ; Humans ; Molecular Structure ; Tumor Stem Cell Assay
Czasopismo naukowe
Tytuł :
Bioactive properties of Sanguisorba minor L. cultivated in central Greece under different fertilization regimes.
Autorzy :
Finimundy TC; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal; CITAB - University of Trás-os-Montes and Alto Douro (UTAD), Department of Agronomy, Vila Real, Portugal.
Karkanis A; Department of Agriculture Crop Production and Rural Environment, University of Thessaly, Fytokou Street, 38446 Volos, Greece.
Fernandes Â; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Petropoulos SA; Department of Agriculture Crop Production and Rural Environment, University of Thessaly, Fytokou Street, 38446 Volos, Greece. Electronic address: .
Calhelha R; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Petrović J; Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Soković M; Institute for Biological Research 'Siniša Stanković', National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Rosa E; CITAB - University of Trás-os-Montes and Alto Douro (UTAD), Department of Agronomy, Vila Real, Portugal.
Barros L; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Ferreira ICFR; Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal. Electronic address: .
Pokaż więcej
Źródło :
Food chemistry [Food Chem] 2020 Oct 15; Vol. 327, pp. 127043. Date of Electronic Publication: 2020 May 12.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
MeSH Terms :
Fertilizers*
Plant Extracts/*chemistry
Plant Extracts/*pharmacology
Sanguisorba/*chemistry
Sanguisorba/*growth & development
Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Cell Proliferation/drug effects ; Greece ; HeLa Cells ; Humans ; Plant Roots/chemistry ; Salmonella typhimurium/drug effects
Czasopismo naukowe
Tytuł :
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
Autorzy :
Douse CH; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Department of Experimental Medical Science, Lund University, Lund, Sweden.
Tchasovnikarova IA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; The Gurdon Institute, Cambridge, UK.
Timms RT; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.
Protasio AV; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.
Seczynska M; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.
Prigozhin DM; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA.
Albecka A; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.; MRC Laboratory of Molecular Biology, Cambridge, UK.
Wagstaff J; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.
Williamson JC; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK.
Freund SMV; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK.
Lehner PJ; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. .
Modis Y; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK. .; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), University of Cambridge School of Clinical Medicine, Cambridge, CB2 0AW, UK. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Oct 02; Vol. 11 (1), pp. 4940. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Epigenesis, Genetic*
DNA Transposable Elements/*genetics
Multiprotein Complexes/*metabolism
Nuclear Proteins/*metabolism
Poly(ADP-ribose) Polymerases/*metabolism
Amino Acid Sequence ; Antigens, Neoplasm/metabolism ; Binding Sites ; Exons/genetics ; Genome ; HEK293 Cells ; HeLa Cells ; Histones/metabolism ; Humans ; Lysine/metabolism ; Magnetic Resonance Spectroscopy ; Methylation ; NAD/metabolism ; Nuclear Proteins/chemistry ; Phosphoproteins/metabolism ; Protein Binding ; Protein Domains ; RNA/metabolism ; RNA Processing, Post-Transcriptional ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Identification of GJA3 p.S50P Mutation in a Chinese Family with Autosomal Dominant Congenital Cataract and Its Underlying Pathogenesis.
Autorzy :
Li H; Eye Center of Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Ophthalmology, Central South University, Changsha, China.
Jiang H; Eye Center of Xiangya Hospital, Central South University, Changsha, China.
Rong R; Eye Center of Xiangya Hospital, Central South University, Changsha, China.
Jiang J; Eye Center of Xiangya Hospital, Central South University, Changsha, China.
Ji D; Eye Center of Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Ophthalmology, Central South University, Changsha, China.
Song W; Eye Center of Xiangya Hospital, Central South University, Changsha, China.
Xia X; Eye Center of Xiangya Hospital, Central South University, Changsha, China.; Hunan Key Laboratory of Ophthalmology, Central South University, Changsha, China.
Pokaż więcej
Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Oct; Vol. 39 (10), pp. 1760-1766. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7430 (Electronic) Linking ISSN: 10445498 NLM ISO Abbreviation: DNA Cell Biol Subsets: MEDLINE
MeSH Terms :
Mutation*
Cataract/*genetics
Connexins/*genetics
Adult ; Cataract/metabolism ; Cataract/pathology ; Child ; Connexins/metabolism ; Endoplasmic Reticulum/metabolism ; Female ; Gap Junctions/metabolism ; Gap Junctions/pathology ; HeLa Cells ; Humans ; Male ; Pedigree ; Protein Binding ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Autorzy :
Bertram K; Department of Structural Dynamics, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
El Ayoubi L; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Dybkov O; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Agafonov DE; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Will CL; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Hartmuth K; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Urlaub H; Bioanalytical Mass Spectrometry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany; Bioanalytics Group, Institute for Clinical Chemistry, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany.
Kastner B; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .
Stark H; Department of Structural Dynamics, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .
Lührmann R; Cellular Biochemistry, MPI for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany. Electronic address: .
Pokaż więcej
Źródło :
Molecular cell [Mol Cell] 2020 Oct 01; Vol. 80 (1), pp. 127-139.e6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
MeSH Terms :
RNA Splicing Factors/*chemistry
RNA Splicing Factors/*metabolism
Spliceosomes/*metabolism
Animals ; Catalysis ; HeLa Cells ; Humans ; Introns/genetics ; Models, Molecular ; Multiprotein Complexes/metabolism ; Multiprotein Complexes/ultrastructure ; Protein Binding ; Protein Stability ; RNA/chemistry ; RNA/metabolism ; Ribonucleoproteins/metabolism ; Saccharomyces cerevisiae/metabolism ; Species Specificity ; Time Factors
Czasopismo naukowe
Tytuł :
MDA-MB-157 Cell Line Presents High Levels of MAD2L2 and Dysregulated Mitosis.
Autorzy :
Pernicone N; Department of Molecular Biology, Ariel University, Ariel, Israel.
Peretz L; Department of Molecular Biology, Ariel University, Ariel, Israel.
Grinshpon S; Department of Molecular Biology, Ariel University, Ariel, Israel.
Listovsky T; Department of Molecular Biology, Ariel University, Ariel, Israel .; The Ariel Center for Applied Cancer Research (ACACR), Ariel University, Ariel, Israel.; Adelson School of Medicine, Ariel University, Ariel, Israel.
Pokaż więcej
Źródło :
Anticancer research [Anticancer Res] 2020 Oct; Vol. 40 (10), pp. 5471-5480.
Typ publikacji :
Journal Article
Journal Info :
Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE
MeSH Terms :
Breast Neoplasms/*genetics
Mad2 Proteins/*genetics
Mitosis/*genetics
Breast Neoplasms/pathology ; Female ; Gene Expression Regulation, Neoplastic/genetics ; HeLa Cells ; Humans ; M Phase Cell Cycle Checkpoints/genetics ; Prometaphase/genetics
Czasopismo naukowe
Tytuł :
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Autorzy :
Yang SW; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Huang X; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Lin W; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Min J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Miller DJ; Department of Structural Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Mayasundari A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Rodrigues P; Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Griffith EC; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Gee CT; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Li L; Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California Irvine, 5270 California Ave, Irvine, CA, 92617, USA.
Li W; Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California Irvine, 5270 California Ave, Irvine, CA, 92617, USA.
Lee RE; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Rankovic Z; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA.
Potts PR; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN, 38105, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Oct 01; Vol. 11 (1), pp. 4931. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Antigens, Neoplasm/*ultrastructure
Neoplasm Proteins/*ultrastructure
Neoplasms/*drug therapy
Ubiquitin-Protein Ligases/*metabolism
mRNA Cleavage and Polyadenylation Factors/*metabolism
Amino Acid Motifs ; Aminoquinolines/pharmacology ; Aminoquinolines/therapeutic use ; Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Carcinogenesis/drug effects ; Drug Screening Assays, Antitumor ; HEK293 Cells ; HeLa Cells ; High-Throughput Screening Assays ; Humans ; Mutagenesis ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Neoplasms/genetics ; Neoplasms/pathology ; Proof of Concept Study ; Protein Binding/drug effects ; Protein Binding/genetics ; Protein Domains/genetics ; Protein Interaction Mapping ; Structure-Activity Relationship ; Substrate Specificity/drug effects ; Substrate Specificity/genetics ; Ubiquitination/drug effects ; Ubiquitination/genetics
Czasopismo naukowe
Tytuł :
Anti-cancer activity of benzoxazinone derivatives via targeting c-Myc G-quadruplex structure.
Autorzy :
Jiang S; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Awadasseid A; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Narva S; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Cao S; College of Pharmacy, East China University of Science and Technology, Shanghai 021, China. Electronic address: .
Tanaka Y; Center for Innovation in Immunoregulative Technology and Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.
Wu Y; Lab of Molecular Immunology, Virus Inspection Department, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China. Electronic address: .
Fu W; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Zhao X; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Wei C; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China.
Zhang W; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: .
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118252. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*administration & dosage
Benzoxazines/*administration & dosage
Drug Delivery Systems/*methods
G-Quadruplexes/*drug effects
Proto-Oncogene Proteins c-myc/*antagonists & inhibitors
Proto-Oncogene Proteins c-myc/*metabolism
A549 Cells ; HT29 Cells ; HeLa Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells
Czasopismo naukowe
Tytuł :
m A Regulator TRMT10C Predicts Poorer Survival and Contributes to Malignant Behavior in Gynecological Cancers.
Autorzy :
Wang Q; Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, P.R. China.
Zhang Q; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, P.R. China.
Huang Y; School of Pharmacy, Shanghai University of Medicine and Health Sciences, Shanghai, P.R. China.
Zhang J; Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, P.R. China.
Pokaż więcej
Źródło :
DNA and cell biology [DNA Cell Biol] 2020 Oct; Vol. 39 (10), pp. 1767-1778. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 9004522 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7430 (Electronic) Linking ISSN: 10445498 NLM ISO Abbreviation: DNA Cell Biol Subsets: MEDLINE
MeSH Terms :
Biomarkers, Tumor/*genetics
Methyltransferases/*genetics
Ovarian Neoplasms/*genetics
Uterine Cervical Neoplasms/*genetics
Adenosine/analogs & derivatives ; Adenosine/metabolism ; Biomarkers, Tumor/metabolism ; Cell Movement ; Cell Proliferation ; Female ; HeLa Cells ; Humans ; Methyltransferases/metabolism ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Uterine Cervical Neoplasms/metabolism ; Uterine Cervical Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Identification of a herpes simplex virus 1 gene encoding neurovirulence factor by chemical proteomics.
Autorzy :
Kato A; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Adachi S; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan.
Kawano S; Department of Computer and Network Engineering, Graduate School of Informatics and Engineering, The University of Electro-Communications, Tokyo, 182-8585, Japan.
Takeshima K; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Watanabe M; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Kitazume S; Preparing Section for New Faculty of Medical Science, Fukushima Medical University, Fukushima City, Fukushima, 960-1295, Japan.
Sato R; Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Kusano H; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan.
Koyanagi N; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Maruzuru Y; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Arii J; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan.
Hatta T; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan.
Natsume T; Molecular Profiling Research Center for Drug Discovery (molprof), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, 135-0064, Japan. .
Kawaguchi Y; Division of Molecular Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan. .; Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan. .; Research Center for Asian Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, 108-8639, Japan. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Sep 29; Vol. 11 (1), pp. 4894. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Encephalitis, Herpes Simplex/*virology
Herpesvirus 1, Human/*pathogenicity
Pyrophosphatases/*metabolism
Viral Proteins/*metabolism
Virulence Factors/*metabolism
Animals ; Brain/pathology ; Brain/virology ; Chlorocebus aethiops ; DNA Replication ; Disease Models, Animal ; Encephalitis, Herpes Simplex/pathology ; Female ; Genes, Viral/genetics ; HEK293 Cells ; HeLa Cells ; Herpesvirus 1, Human/genetics ; Humans ; Mice ; Protein Biosynthesis ; Proteomics/methods ; Vero Cells ; Viral Proteins/genetics ; Virulence Factors/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Evolutionary Arms Race between Virus and Host Drives Genetic Diversity in Bat Severe Acute Respiratory Syndrome-Related Coronavirus Spike Genes.
Autorzy :
Guo H; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.; University of Chinese Academy of Sciences, Beijing, China.
Hu BJ; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Yang XL; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Zeng LP; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Li B; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Ouyang S; The Key Laboratory of Innate Immune Biology of Fujian Province, Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of the Ministry of Education, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Shi ZL; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China .
Pokaż więcej
Źródło :
Journal of virology [J Virol] 2020 Sep 29; Vol. 94 (20). Date of Electronic Publication: 2020 Sep 29 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
MeSH Terms :
Biological Coevolution*
Chiroptera/*virology
SARS Virus/*genetics
Spike Glycoprotein, Coronavirus/*genetics
Animals ; Binding Sites ; Chiroptera/classification ; Chiroptera/genetics ; Coronavirus Infections/virology ; Evolution, Molecular ; Genetic Variation ; HeLa Cells ; Humans ; Models, Molecular ; Mutation ; Peptidyl-Dipeptidase A/genetics ; Peptidyl-Dipeptidase A/metabolism ; Phylogeny ; Protein Binding ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; Selection, Genetic ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism
Czasopismo naukowe
Tytuł :
MicroRNA-Independent Modulation of DICER1 Expression by hAgo2.
Autorzy :
Yang CH; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Li HC; Department of Biochemistry, School of Medicine, Tzu Chi University, Hualien, Taiwan.
Ku TS; Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, Taiwan.
Wu CH; Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, Taiwan.
Sim KC; Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, Taiwan.
Lo SY; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan .; Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, Taiwan.; Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Pokaż więcej
Źródło :
Molecular and cellular biology [Mol Cell Biol] 2020 Sep 28; Vol. 40 (20). Date of Electronic Publication: 2020 Sep 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 8109087 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-5549 (Electronic) Linking ISSN: 02707306 NLM ISO Abbreviation: Mol Cell Biol Subsets: MEDLINE
MeSH Terms :
Argonaute Proteins/*genetics
DEAD-box RNA Helicases/*genetics
Gene Expression Regulation, Neoplastic/*genetics
MicroRNAs/*genetics
Neoplasms/*genetics
Ribonuclease III/*genetics
3' Untranslated Regions/genetics ; A549 Cells ; Argonaute Proteins/metabolism ; Binding Sites/genetics ; CRISPR-Cas Systems ; Cell Line, Tumor ; DEAD-box RNA Helicases/metabolism ; HEK293 Cells ; HeLa Cells ; Heterogeneous Nuclear Ribonucleoprotein D0/genetics ; Heterogeneous Nuclear Ribonucleoprotein D0/metabolism ; Humans ; RNA Interference ; RNA, Messenger/genetics ; RNA, Small Interfering/genetics ; Ribonuclease III/metabolism
Czasopismo naukowe
Tytuł :
The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion.
Autorzy :
Faris R; Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
McCullough A; Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Andersen SE; Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Moninger TO; Central Microscopy Research Facility, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Weber MM; Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
Pokaż więcej
Źródło :
PLoS pathogens [PLoS Pathog] 2020 Sep 18; Vol. 16 (9), pp. e1008878. Date of Electronic Publication: 2020 Sep 18 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
MeSH Terms :
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Chlamydia trachomatis*/genetics
Chlamydia trachomatis*/metabolism
Chlamydia trachomatis*/pathogenicity
Cell Membrane/*metabolism
Wiskott-Aldrich Syndrome Protein, Neuronal/*metabolism
Actin-Related Protein 2-3 Complex/genetics ; Actin-Related Protein 2-3 Complex/metabolism ; Cell Membrane/genetics ; Cell Membrane/pathology ; HeLa Cells ; Humans ; Mutation ; Protein Domains ; Pseudopodia/genetics ; Pseudopodia/metabolism ; Wiskott-Aldrich Syndrome Protein, Neuronal/genetics
Czasopismo naukowe
Tytuł :
Isolation and characterization of severe acute respiratory syndrome coronavirus 2 in Turkey.
Autorzy :
Pavel STI; Department of Microbiology, Medical Faculty, Erciyes University, Kayseri, Turkey.; Vaccine Research, Development and Application Center, Erciyes University, Kayseri, Turkey.
Yetiskin H; Department of Microbiology, Medical Faculty, Erciyes University, Kayseri, Turkey.; Vaccine Research, Development and Application Center, Erciyes University, Kayseri, Turkey.
Aydin G; Department of Microbiology, Medical Faculty, Erciyes University, Kayseri, Turkey.; Vaccine Research, Development and Application Center, Erciyes University, Kayseri, Turkey.
Holyavkin C; Gen Era Diagnostics Inc. Barbaros, Istanbul, Turkey.
Uygut MA; Vaccine Research, Development and Application Center, Erciyes University, Kayseri, Turkey.
Dursun ZB; Department of Microbiology and Infectious Disease, Kayseri City Training and Research Hospital, Kayseri, Turkey.
Celik İ; Department of Microbiology and Infectious Disease, Kayseri City Training and Research Hospital, Kayseri, Turkey.
Cevik C; Gen Era Diagnostics Inc. Barbaros, Istanbul, Turkey.
Ozdarendeli A; Department of Microbiology, Medical Faculty, Erciyes University, Kayseri, Turkey.; Vaccine Research, Development and Application Center, Erciyes University, Kayseri, Turkey.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 Sep 16; Vol. 15 (9), pp. e0238614. Date of Electronic Publication: 2020 Sep 16 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
Pandemics*
Betacoronavirus/*isolation & purification
Virus Cultivation/*methods
Animals ; Australia ; Betacoronavirus/genetics ; Betacoronavirus/physiology ; Canada ; Cell Line ; Chlorocebus aethiops ; Contact Tracing ; Coronavirus Infections ; Cytopathogenic Effect, Viral ; DNA, Complementary/genetics ; DNA, Viral/genetics ; England ; Genome, Viral ; HeLa Cells ; Humans ; Iran ; Kuwait ; Macaca mulatta ; Nasopharynx/virology ; Phylogeny ; Pneumonia, Viral ; Sequence Analysis, DNA ; Travel ; Turkey/epidemiology ; Vero Cells ; Virus Replication
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4.
Autorzy :
Bohlen J; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; CellNetworks-Cluster of Excellence, Heidelberg University, Heidelberg, Germany.; Heidelberg University, 69120, Heidelberg, Germany.; Heidelberg Biosciences International Graduate School (HBIGS), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany.
Harbrecht L; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Heidelberg University, 69120, Heidelberg, Germany.
Blanco S; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Heidelberg University, 69120, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany.
Clemm von Hohenberg K; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; CellNetworks-Cluster of Excellence, Heidelberg University, Heidelberg, Germany.; Heidelberg University, 69120, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany.
Fenzl K; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Heidelberg University, 69120, Heidelberg, Germany.; Heidelberg Biosciences International Graduate School (HBIGS), Heidelberg, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg, D-69120, Germany.
Kramer G; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg, D-69120, Germany.
Bukau B; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany.; Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg, D-69120, Germany.
Teleman AA; German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. .; CellNetworks-Cluster of Excellence, Heidelberg University, Heidelberg, Germany. .; Heidelberg University, 69120, Heidelberg, Germany. .; Heidelberg Biosciences International Graduate School (HBIGS), Heidelberg, Germany. .; National Center for Tumor Diseases (NCT), partner site, Heidelberg, Germany. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2020 Sep 16; Vol. 11 (1), pp. 4676. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 Subsets: MEDLINE
MeSH Terms :
Protein Biosynthesis*
Activating Transcription Factor 4/*genetics
Eukaryotic Initiation Factors/*metabolism
Ribosomes/*metabolism
5' Untranslated Regions ; Activating Transcription Factor 4/metabolism ; Cell Cycle Proteins/genetics ; Codon ; Eukaryotic Initiation Factor-2/genetics ; Eukaryotic Initiation Factor-2/metabolism ; Eukaryotic Initiation Factors/genetics ; Gene Expression Regulation ; HeLa Cells ; Humans ; Neoplasms/genetics ; Oncogene Proteins/genetics ; Oncogenes ; Open Reading Frames ; RNA, Messenger ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; Ribosome Subunits, Small, Eukaryotic/genetics ; Ribosome Subunits, Small, Eukaryotic/metabolism ; Ribosomes/genetics
Czasopismo naukowe
Tytuł :
Berberine inhibits cancer cells growth by suppressing fatty acid synthesis and biogenesis of extracellular vesicles.
Autorzy :
Gu S; Department of Biliary-Pancreatic Minimally Invasive Surgery, the First Affiliated Hospital, Shantou University Medical College, Guangdong, China; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Song X; Center for Cancer Research, Shantou University Medical College, Guangdong, China.
Xie R; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Ouyang C; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Xie L; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China; Biomedical Research Center, Shantou University Medical College, Guangdong, China.
Li Q; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Su T; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Xu M; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Xu T; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China.
Huang D; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China. Electronic address: .
Liang B; Section of Cell Biology and Genetics, Shantou University Medical College, Guangdong, China; Biomedical Research Center, Shantou University Medical College, Guangdong, China. Electronic address: .
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118122. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Antineoplastic Agents/*pharmacology
Berberine/*pharmacology
Extracellular Vesicles/*metabolism
Fatty Acids/*metabolism
Neoplasms/*drug therapy
AMP-Activated Protein Kinases/metabolism ; Acetyl-CoA Carboxylase/metabolism ; Blotting, Western ; Cell Cycle/drug effects ; Cell Proliferation/drug effects ; Citric Acid/pharmacology ; Extracellular Vesicles/drug effects ; HCT116 Cells/drug effects ; HeLa Cells/drug effects ; Humans
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies