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Wyszukujesz frazę ""Healthy Volunteers"" wg kryterium: Temat


Tytuł:
Finite element analysis of biomechanical effects of percutaneous cement discoplasty in scoliosis.
Autorzy:
Yang C; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Wang F; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Huang X; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Zhang H; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Shi S; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Zhang FM; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Gao J; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Yu X; Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China. .
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Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2024 Apr 12; Vol. 25 (1), pp. 285. Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Scoliosis*/diagnostic imaging
Scoliosis*/surgery
Humans ; Finite Element Analysis ; Bone Cements/therapeutic use ; Spine ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
The effect of an anti-malarial herbal remedy, Maytenus senegalensis, on electrocardiograms of healthy Tanzanian volunteers.
Autorzy:
Kassimu KR; Bagamoyo Clinical Trial Facility, Ifakara Health Institute, 74, Bagamoyo, Tanzania. .; Department of Parasitology, Muhimbili University of Health and Allied Sciences, 65001, Dar es Salaam, Tanzania. .
Ali AM; Bagamoyo Clinical Trial Facility, Ifakara Health Institute, 74, Bagamoyo, Tanzania.
Omolo JJ; Traditional Medicine Research and Development Center, National Institute for Medical Research, 9653, Dar es Salaam, Tanzania.
Mdemu A; Traditional Medicine Research and Development Center, National Institute for Medical Research, 9653, Dar es Salaam, Tanzania.
Machumi F; Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, 65001, Dar es Salaam, Tanzania.
Ngasala B; Department of Parasitology, Muhimbili University of Health and Allied Sciences, 65001, Dar es Salaam, Tanzania.
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Źródło:
Malaria journal [Malar J] 2024 Apr 12; Vol. 23 (1), pp. 103. Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/pharmacology
Maytenus*
Artemisinins*
Malaria*/drug therapy
Adult ; Male ; Humans ; Healthy Volunteers ; Tanzania ; Volunteers ; Electrocardiography
Czasopismo naukowe
Tytuł:
The Effect of Sleep Deprivation on Brain Fingerprint Stability: A Magnetoencephalography Validation Study.
Autorzy:
Ambrosanio M; Department of Economics, Law, Cybersecurity and Sports Sciences (DiSEGIM), University of Naples 'Parthenope', 80035 Nola, Italy.
Troisi Lopez E; Institute of Applied Sciences and Intelligent Systems, National Research Council, 80078 Pozzuoli, Italy.
Polverino A; Institute of Diagnosis and Treatment Hermitage Capodimonte, 80145 Naples, Italy.
Minino R; Department of Medical, Movement and Wellness Sciences (DiSMMEB), University of Naples 'Parthenope', 80133 Naples, Italy.
Cipriano L; Department of Medical, Movement and Wellness Sciences (DiSMMEB), University of Naples 'Parthenope', 80133 Naples, Italy.
Vettoliere A; Institute of Applied Sciences and Intelligent Systems, National Research Council, 80078 Pozzuoli, Italy.
Granata C; Institute of Applied Sciences and Intelligent Systems, National Research Council, 80078 Pozzuoli, Italy.
Mandolesi L; Department of Humanities, University of Naples Federico II, 80133 Naples, Italy.
Curcio G; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Sorrentino G; Institute of Applied Sciences and Intelligent Systems, National Research Council, 80078 Pozzuoli, Italy.; Institute of Diagnosis and Treatment Hermitage Capodimonte, 80145 Naples, Italy.; Department of Medical, Movement and Wellness Sciences (DiSMMEB), University of Naples 'Parthenope', 80133 Naples, Italy.
Sorrentino P; Institute of Applied Sciences and Intelligent Systems, National Research Council, 80078 Pozzuoli, Italy.; Institut de Neurosciences des Systèmes, Aix-Marseille Université, 13005 Marseille, France.; Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Apr 04; Vol. 24 (7). Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:
Journal Article
MeSH Terms:
Sleep Deprivation*
Magnetoencephalography*
Young Adult ; Humans ; Brain ; Health Status ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC-HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel.
Autorzy:
Savaryn JP; AbbVie Inc., North Chicago, Illinois, USA.
Smith RL; AbbVie Inc., North Chicago, Illinois, USA.
Rosebraugh M; AbbVie Inc., North Chicago, Illinois, USA.
Neenan M; AbbVie Inc., North Chicago, Illinois, USA.
Burton R; AbbVie Inc., North Chicago, Illinois, USA.
Marsh K; AbbVie Inc., North Chicago, Illinois, USA.
Wagner D; AbbVie Inc., North Chicago, Illinois, USA.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Apr; Vol. 12 (2), pp. e1190.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Carbidopa*/pharmacokinetics
Parkinson Disease*/drug therapy
Humans ; Levodopa/pharmacokinetics ; Antiparkinson Agents/pharmacokinetics ; Cross-Over Studies ; Healthy Volunteers ; Gels/therapeutic use ; Dopamine Agonists
Czasopismo naukowe
Tytuł:
The myeloperoxidase inhibitor mitiperstat (AZD4831) does not prolong the QT interval at expected therapeutic doses.
Autorzy:
Parkinson J; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Sundell J; Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Rekić D; BioPharmaceuticals, Global Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden.
Nelander K; Late CVRM Biometrics, Late CVRM, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Ericsson H; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Ebrahimi A; Cardiovascular Safety Centre of Excellence, Global Patient Safety, Oncology R&D, AstraZeneca, Gothenburg, Sweden.
Dota C; Cardiovascular Safety Centre of Excellence, Global Patient Safety, Oncology R&D, AstraZeneca, Gothenburg, Sweden.
Sunnåker M; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Apr; Vol. 12 (2), pp. e1184.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Pyrroles*
Peroxidase*
Pyrimidines*
Humans ; Male ; Electrocardiography ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Population pharmacokinetic modeling of oral brepocitinib in healthy volunteers and patients with immuno-inflammatory diseases.
Autorzy:
Maleki F; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Clark E; Department of Mathematics, University of Utah, Salt Lake City, Utah, USA.
Banfield C; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Byon W; Amador Bioscience, Ann Arbor, Michigan, USA.
Nicholas T; Clinical Pharmacology and Bioanalytics, Worldwide Research, Development and Medical, Pfizer Inc, Groton, Connecticut, USA.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Apr; Vol. 13 (4), pp. 551-562. Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Janus Kinase Inhibitors*
Humans ; Male ; Female ; Healthy Volunteers ; Biological Availability ; Administration, Oral ; Body Weight ; Models, Biological
Czasopismo naukowe
Tytuł:
A Novel Framework Based on Deep Learning Architecture for Continuous Human Activity Recognition with Inertial Sensors.
Autorzy:
Suglia V; Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari, 70126 Bari, Italy.
Palazzo L; Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari, 70126 Bari, Italy.; Scientific Clinical Institutes Maugeri SPA SB IRCCS, 70124 Bari, Italy.
Bevilacqua V; Department of Electrical and Information Engineering (DEI), Polytechnic University of Bari, 70126 Bari, Italy.; Apulian Bioengineering S.R.L.,Via delle Violette 14, 70026 Modugno, Italy.
Passantino A; Scientific Clinical Institutes Maugeri SPA SB IRCCS, 70124 Bari, Italy.
Pagano G; Scientific Clinical Institutes Maugeri SPA SB IRCCS, 70124 Bari, Italy.
D'Addio G; Scientific Clinical Institutes Maugeri SPA SB IRCCS, 70124 Bari, Italy.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2024 Mar 29; Vol. 24 (7). Date of Electronic Publication: 2024 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Deep Learning*
Humans ; Human Activities ; Activities of Daily Living ; Engineering ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Self-protective behaviors of Thai village health volunteers in community engagement during a COVID-19 outbreak: interpretation using the health belief model.
Autorzy:
Wongrith P; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand. .; The Excellence Center Dengue and Community Public Health (EC for DACH), Walailak University, Tha Sala, Nakhon Si Thammarat, Thailand. .
Buakate P; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.; The Excellence Center Dengue and Community Public Health (EC for DACH), Walailak University, Tha Sala, Nakhon Si Thammarat, Thailand.
Doylee L; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.
Phonla N; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.
Dadras O; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Frampton G; Southampton Health Technology Assessments Centre (SHTAC), Faculty of Medicine, University of Southampton, Southampton, UK.
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Źródło:
BMC primary care [BMC Prim Care] 2024 Mar 28; Vol. 25 (1), pp. 102. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/prevention & control
Humans ; Female ; Male ; Thailand/epidemiology ; Cross-Sectional Studies ; Pandemics/prevention & control ; Healthy Volunteers ; Health Belief Model
Czasopismo naukowe
Tytuł:
Investigating Vα7.2 T Cell and MAIT Cell Profiles Using Flow Cytometry in Healthy Subjects and Subjects with Atopic Dermatitis.
Autorzy:
Singh P; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gaspar K; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Szegedi A; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Sajtos L; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Barath S; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Hevessy Z; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 20; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Mucosal-Associated Invariant T Cells*
Dermatitis, Atopic*
Humans ; Flow Cytometry ; Tumor Necrosis Factor-alpha ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
The Effects of the Steroids 5-Androstenediol and Dehydroepiandrosterone and Their Synthetic Derivatives on the Viability of K562, HeLa, and Wi-38 Cells and the Luminol-Stimulated Chemiluminescence of Peripheral Blood Mononuclear Cells from Healthy Volunteers.
Autorzy:
Sokolov MN; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Rozhkov VV; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Uspenskaya ME; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Ulchenko DN; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Shmygarev VI; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Trukhan VM; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Churakov AV; Kurnakov Institute of General and Inorganic Chemistry, the Russian Academy of Sciences, 31 Leninsky Av., Moscow 119991, Russia.
Shimanovsky NL; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Fedotcheva TA; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 19; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Androstenediol*
Dehydroepiandrosterone*/pharmacology
Humans ; Luminol ; Leukocytes, Mononuclear ; Healthy Volunteers ; K562 Cells ; Luminescence ; Propionates ; Steroids
Czasopismo naukowe
Tytuł:
Stationary stable cross-correlation pattern and task specific deviations in unresponsive wakefulness syndrome as well as clinically healthy subjects.
Autorzy:
Apablaza-Yevenes DE; Instituto de Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Morelos, México.
Corsi-Cabrera M; Unidad de Investigación en Neurodesarrollo, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Martinez-Guerrero A; Instituto de Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Morelos, México.
Northoff G; Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.; Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, People's Republic of China.; Mental Health Centre, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Romaniello C; Santa Viola Hospital, Colibrì Consortium, Bologna, Italy.
Farinelli M; Villa Bellombra Hospital, Colibrì Consortium, Bologna, Italy.
Bertoletti E; Santa Viola Hospital, Colibrì Consortium, Bologna, Italy.
Müller MF; Centro de Ciencias de la Complejidad (C3), Universidad Nacional Autónoma de México, Ciudad de México, México.; Centro de Investigación en Ciencias, Universidad Autónoma del Estado de Morelos, Morelos, México.; Centro Internacional de Ciencias A.C., Morelos, México.
Muñoz-Torres Z; Centro de Ciencias de la Complejidad (C3), Universidad Nacional Autónoma de México, Ciudad de México, México.; Facultad de Psicología, Universidad Nacional Autónoma de México, Ciudad de México, México.
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Źródło:
PloS one [PLoS One] 2024 Mar 15; Vol. 19 (3), pp. e0300075. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Wakefulness*/physiology
Brain*
Humans ; Healthy Volunteers ; Electroencephalography/methods ; Sleep/physiology ; Syndrome ; Persistent Vegetative State
Czasopismo naukowe
Tytuł:
Reproduction of forearm rotation dynamic using intensity-based biplane 2D-3D registration matching method.
Autorzy:
Shiode R; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Miyamura S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Kazui A; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yamamoto N; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Miyake T; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Iwahashi T; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tanaka H; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Otake Y; Division of Information Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, 630-0192, Japan.
Sato Y; Division of Information Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, 630-0192, Japan.
Murase T; Department of Orthopaedic Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai, Osaka, 599-8247, Japan.
Abe S; Department of Orthopaedic Surgery, Toyonaka City Hospital, 4-14-1 Shibahara, Toyonaka, Osaka, 560-8565, Japan.
Okada S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Oka K; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 06; Vol. 14 (1), pp. 5518. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Forearm*/diagnostic imaging
Upper Extremity*
Humans ; Reproduction ; Fluoroscopy ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Clinical evaluation of PF614, a novel TAAP prodrug of oxycodone, versus OxyContin in a multi-ascending dose study with a bioequivalence arm in healthy volunteers.
Autorzy:
Kirkpatrick DL; Ensysce Biosciences Inc., La Jolla, California, USA.
Evans C; Ensysce Biosciences Inc., La Jolla, California, USA.
Pestano LA; Ensysce Biosciences Inc., La Jolla, California, USA.
Millard J; Ensysce Biosciences Inc., La Jolla, California, USA.
Johnston M; ICON, Salt Lake City, Utah, USA.
Mick E; ICON, Lenexa, Kansas, USA.
Schmidt WK; Ensysce Biosciences Inc., La Jolla, California, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13765.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxycodone*
Prodrugs*/adverse effects
Humans ; Administration, Oral ; Analgesics, Opioid ; Cross-Over Studies ; Healthy Volunteers ; Naltrexone/adverse effects ; Therapeutic Equivalency
Czasopismo naukowe
Tytuł:
Bioavailability of three novel oral, sustained-release pellets, relative to an immediate-release tablet containing 500 mg flucytosine: A randomized, open-label, crossover study in healthy volunteers.
Autorzy:
Goyal V; Drugs for Neglected Diseases Initiative, New York, New York, USA.
Krantz E; FARMOVS, Bloemfontein, South Africa.
Simon F; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Neven A; Luxembourg Institute of Health, Strassen, Luxembourg.
Eriksson J; Pharmetheus, Uppsala, Sweden.
Saayman A; FARMOVS, Bloemfontein, South Africa.
Ibnou Zekri Lassout N; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Louis M; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Robinson S; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Deshmukh A; Viatris, Hyderabad, India.
Antarkar A; Viatris, Hyderabad, India.
Ruffell C; DNDi GARDP Southern Africa, Cape Town, South Africa.
Victor S; FARMOVS, Bloemfontein, South Africa.
Chenel M; Pharmetheus, Uppsala, Sweden.
Celebic A; Luxembourg Institute of Health, Strassen, Luxembourg.
Caplain H; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Gillon JY; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Ribeiro I; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13756.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Flucytosine*
Humans ; Biological Availability ; Healthy Volunteers ; Cross-Over Studies ; Delayed-Action Preparations ; Tablets ; Drug Implants ; Administration, Oral
Czasopismo naukowe
Tytuł:
Clinical pharmacokinetics of atropine oral gel formulation in healthy volunteers.
Autorzy:
Parrot M; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Yathavan B; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Averin O; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Hoggard L; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Rower JE; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Voight M; Investigational Drug Service, Pharmacy Services, University of Utah Hospital, Salt Lake City, Utah, USA.
Greene D; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Tarrell A; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Whelan A; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Ghandehari H; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Murphy N; Division of Complex Care, Department of Pediatrics, University of Utah Health, Salt Lake City, Utah, USA.
Yellepeddi V; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13753.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Quality of Life*
Sialorrhea*/drug therapy
Adult ; Child ; Humans ; Healthy Volunteers ; Area Under Curve ; Ophthalmic Solutions/adverse effects ; Atropine Derivatives ; Administration, Oral
Czasopismo naukowe
Tytuł:
Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin-A receptor antagonist.
Autorzy:
Liu Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Wang W; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Qian H; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Gui Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Wang Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Song R; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Chen Q; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Rowinsky E; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Wang S; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Liang X; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Gu K; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhou B; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhang W; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhang L; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Yu C; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Jia J; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13750.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Asian People*
Humans ; Bile Acids and Salts ; China ; Fasting ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects.
Autorzy:
Won H; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Yoon DY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Lee S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea.
Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Oh J; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Pharmacology, Jeju National University College of Medicine, Jeju, Republic of Korea.
Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Yoo SK; Glaceum Inc., Suwon, Korea.
Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13744.
Typ publikacji:
Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Obesity Agents*/adverse effects
Male ; Humans ; Biological Availability ; Cross-Over Studies ; Healthy Volunteers ; Meals
Czasopismo naukowe
Tytuł:
Safety and efficacy of REGENDIL™ infused hair growth promoting product in adult human subject having hair fall complaints (alopecia).
Autorzy:
Merja A; NovoBliss Research Private Limited, Ahmedabad, India.
Patel N; NovoBliss Research Private Limited, Ahmedabad, India.
Patel M; NovoBliss Research Private Limited, Ahmedabad, India.
Patnaik S; Anveya Living Private Limited, Gurugram, India.
Ahmed A; Anveya Living Private Limited, Gurugram, India.
Maulekhi S; Anveya Living Private Limited, Gurugram, India.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Mar; Vol. 23 (3), pp. 938-948. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Alopecia*/diagnosis
Alopecia*/drug therapy
Hair*
Adult ; Humans ; Research Subjects ; Scalp ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Hippocampal volume changes after (R,S)-ketamine administration in patients with major depressive disorder and healthy volunteers.
Autorzy:
Evans JW; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA. .
Graves MC; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.
Nugent AC; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.; MEG Core, NIMH, Bethesda, MD, USA.
Zarate CA Jr; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4538. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Depressive Disorder, Major*/diagnostic imaging
Depressive Disorder, Major*/drug therapy
Depressive Disorder, Major*/pathology
Depressive Disorder, Treatment-Resistant*
Ketamine*/pharmacology
Ketamine*/therapeutic use
Humans ; Healthy Volunteers ; Hippocampus/pathology ; Treatment Outcome ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
The Binding Properties of Antibodies to Z-DNA in the Sera of Normal Healthy Subjects.
Autorzy:
Pisetsky DS; Medical Research Service, Durham Veterans Administration Medical Center, Durham, NC 27705, USA.; Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Gedye MJ; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.
David LA; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.; Duke Microbiome Center, School of Medicine, Duke University, Durham, NC 27710, USA.
Spencer DM; Medical Research Service, Durham Veterans Administration Medical Center, Durham, NC 27705, USA.; Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC 27710, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
DNA, Z-Form*
Animals ; Humans ; Healthy Volunteers ; Antibodies, Antinuclear ; Immunoglobulin G ; Immunoglobulin A
Czasopismo naukowe

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