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Tytuł:
Self-protective behaviors of Thai village health volunteers in community engagement during a COVID-19 outbreak: interpretation using the health belief model.
Autorzy:
Wongrith P; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand. .; The Excellence Center Dengue and Community Public Health (EC for DACH), Walailak University, Tha Sala, Nakhon Si Thammarat, Thailand. .
Buakate P; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.; The Excellence Center Dengue and Community Public Health (EC for DACH), Walailak University, Tha Sala, Nakhon Si Thammarat, Thailand.
Doylee L; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.
Phonla N; School of Public Health, Walailak University, 222 Thaiburi, Tha Sala, Nakhon Si Thammarat, 80161, Thailand.
Dadras O; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Frampton G; Southampton Health Technology Assessments Centre (SHTAC), Faculty of Medicine, University of Southampton, Southampton, UK.
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Źródło:
BMC primary care [BMC Prim Care] 2024 Mar 28; Vol. 25 (1), pp. 102. Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/prevention & control
Humans ; Female ; Male ; Thailand/epidemiology ; Cross-Sectional Studies ; Pandemics/prevention & control ; Healthy Volunteers ; Health Belief Model
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigating Vα7.2 T Cell and MAIT Cell Profiles Using Flow Cytometry in Healthy Subjects and Subjects with Atopic Dermatitis.
Autorzy:
Singh P; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gaspar K; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Szegedi A; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Sajtos L; Department of Dermatology and Venereology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Barath S; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Hevessy Z; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 20; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Mucosal-Associated Invariant T Cells*
Dermatitis, Atopic*
Humans ; Flow Cytometry ; Tumor Necrosis Factor-alpha ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Effects of the Steroids 5-Androstenediol and Dehydroepiandrosterone and Their Synthetic Derivatives on the Viability of K562, HeLa, and Wi-38 Cells and the Luminol-Stimulated Chemiluminescence of Peripheral Blood Mononuclear Cells from Healthy Volunteers.
Autorzy:
Sokolov MN; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Rozhkov VV; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Uspenskaya ME; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Ulchenko DN; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Shmygarev VI; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Trukhan VM; Institute for Translation Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2 Bolshaya Pirogovskaya St., Bld. 4, Moscow 119435, Russia.
Churakov AV; Kurnakov Institute of General and Inorganic Chemistry, the Russian Academy of Sciences, 31 Leninsky Av., Moscow 119991, Russia.
Shimanovsky NL; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
Fedotcheva TA; Laboratory of Molecular Pharmacology, Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997, Russia.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 19; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Androstenediol*
Dehydroepiandrosterone*/pharmacology
Humans ; Luminol ; Leukocytes, Mononuclear ; Healthy Volunteers ; K562 Cells ; Luminescence ; Propionates ; Steroids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Stationary stable cross-correlation pattern and task specific deviations in unresponsive wakefulness syndrome as well as clinically healthy subjects.
Autorzy:
Apablaza-Yevenes DE; Instituto de Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Morelos, México.
Corsi-Cabrera M; Unidad de Investigación en Neurodesarrollo, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, México.
Martinez-Guerrero A; Instituto de Ciencias Básicas y Aplicadas, Universidad Autónoma del Estado de Morelos, Morelos, México.
Northoff G; Institute of Mental Health Research, University of Ottawa, Ottawa, Ontario, Canada.; Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, People's Republic of China.; Mental Health Centre, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Romaniello C; Santa Viola Hospital, Colibrì Consortium, Bologna, Italy.
Farinelli M; Villa Bellombra Hospital, Colibrì Consortium, Bologna, Italy.
Bertoletti E; Santa Viola Hospital, Colibrì Consortium, Bologna, Italy.
Müller MF; Centro de Ciencias de la Complejidad (C3), Universidad Nacional Autónoma de México, Ciudad de México, México.; Centro de Investigación en Ciencias, Universidad Autónoma del Estado de Morelos, Morelos, México.; Centro Internacional de Ciencias A.C., Morelos, México.
Muñoz-Torres Z; Centro de Ciencias de la Complejidad (C3), Universidad Nacional Autónoma de México, Ciudad de México, México.; Facultad de Psicología, Universidad Nacional Autónoma de México, Ciudad de México, México.
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Źródło:
PloS one [PLoS One] 2024 Mar 15; Vol. 19 (3), pp. e0300075. Date of Electronic Publication: 2024 Mar 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Wakefulness*/physiology
Brain*
Humans ; Healthy Volunteers ; Electroencephalography/methods ; Sleep/physiology ; Syndrome ; Persistent Vegetative State
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Reproduction of forearm rotation dynamic using intensity-based biplane 2D-3D registration matching method.
Autorzy:
Shiode R; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Miyamura S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Kazui A; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yamamoto N; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Miyake T; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Iwahashi T; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tanaka H; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Otake Y; Division of Information Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, 630-0192, Japan.
Sato Y; Division of Information Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara, 630-0192, Japan.
Murase T; Department of Orthopaedic Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai, Osaka, 599-8247, Japan.
Abe S; Department of Orthopaedic Surgery, Toyonaka City Hospital, 4-14-1 Shibahara, Toyonaka, Osaka, 560-8565, Japan.
Okada S; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Oka K; Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 06; Vol. 14 (1), pp. 5518. Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Forearm*/diagnostic imaging
Upper Extremity*
Humans ; Reproduction ; Fluoroscopy ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical evaluation of PF614, a novel TAAP prodrug of oxycodone, versus OxyContin in a multi-ascending dose study with a bioequivalence arm in healthy volunteers.
Autorzy:
Kirkpatrick DL; Ensysce Biosciences Inc., La Jolla, California, USA.
Evans C; Ensysce Biosciences Inc., La Jolla, California, USA.
Pestano LA; Ensysce Biosciences Inc., La Jolla, California, USA.
Millard J; Ensysce Biosciences Inc., La Jolla, California, USA.
Johnston M; ICON, Salt Lake City, Utah, USA.
Mick E; ICON, Lenexa, Kansas, USA.
Schmidt WK; Ensysce Biosciences Inc., La Jolla, California, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13765.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Oxycodone*
Prodrugs*/adverse effects
Humans ; Administration, Oral ; Analgesics, Opioid ; Cross-Over Studies ; Healthy Volunteers ; Naltrexone/adverse effects ; Therapeutic Equivalency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bioavailability of three novel oral, sustained-release pellets, relative to an immediate-release tablet containing 500 mg flucytosine: A randomized, open-label, crossover study in healthy volunteers.
Autorzy:
Goyal V; Drugs for Neglected Diseases Initiative, New York, New York, USA.
Krantz E; FARMOVS, Bloemfontein, South Africa.
Simon F; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Neven A; Luxembourg Institute of Health, Strassen, Luxembourg.
Eriksson J; Pharmetheus, Uppsala, Sweden.
Saayman A; FARMOVS, Bloemfontein, South Africa.
Ibnou Zekri Lassout N; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Louis M; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Robinson S; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Deshmukh A; Viatris, Hyderabad, India.
Antarkar A; Viatris, Hyderabad, India.
Ruffell C; DNDi GARDP Southern Africa, Cape Town, South Africa.
Victor S; FARMOVS, Bloemfontein, South Africa.
Chenel M; Pharmetheus, Uppsala, Sweden.
Celebic A; Luxembourg Institute of Health, Strassen, Luxembourg.
Caplain H; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Gillon JY; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
Ribeiro I; Drugs for Neglected Diseases Initiative, Geneva, Switzerland.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13756.
Typ publikacji:
Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article
MeSH Terms:
Flucytosine*
Humans ; Biological Availability ; Healthy Volunteers ; Cross-Over Studies ; Delayed-Action Preparations ; Tablets ; Drug Implants ; Administration, Oral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinical pharmacokinetics of atropine oral gel formulation in healthy volunteers.
Autorzy:
Parrot M; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Yathavan B; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Averin O; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Hoggard L; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Rower JE; Department of Pharmacology and Toxicology and Center for Human Toxicology, University of Utah, Salt Lake City, Utah, USA.
Voight M; Investigational Drug Service, Pharmacy Services, University of Utah Hospital, Salt Lake City, Utah, USA.
Greene D; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Tarrell A; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Whelan A; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Ghandehari H; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
Murphy N; Division of Complex Care, Department of Pediatrics, University of Utah Health, Salt Lake City, Utah, USA.
Yellepeddi V; Division of Clinical Pharmacology, Department of Pediatrics, Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.; Department of Molecular Pharmaceutics, Utah Center for Nanomedicine, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13753.
Typ publikacji:
Journal Article
MeSH Terms:
Quality of Life*
Sialorrhea*/drug therapy
Adult ; Child ; Humans ; Healthy Volunteers ; Area Under Curve ; Ophthalmic Solutions/adverse effects ; Atropine Derivatives ; Administration, Oral
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin-A receptor antagonist.
Autorzy:
Liu Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Wang W; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Qian H; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Gui Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Wang Y; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Song R; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Chen Q; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Rowinsky E; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Wang S; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Liang X; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Gu K; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhou B; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhang W; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Zhang L; Biocity Biopharmaceutics Co., Ltd., Wuxi, China.
Yu C; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
Jia J; Shanghai Xuhui Central Hospital/Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research and Quality Consistency Evaluation for Drugs, Shanghai Engineering Research Center, Shanghai, China.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13750.
Typ publikacji:
Clinical Trial, Phase I; Journal Article
MeSH Terms:
Asian People*
Humans ; Bile Acids and Salts ; China ; Fasting ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects.
Autorzy:
Won H; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Yoon DY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Lee S; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, Korea.
Cho JY; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Oh J; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Pharmacology, Jeju National University College of Medicine, Jeju, Republic of Korea.
Jang IJ; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.
Yoo SK; Glaceum Inc., Suwon, Korea.
Yu KS; Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Korea.; Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13744.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Anti-Obesity Agents*/adverse effects
Male ; Humans ; Biological Availability ; Cross-Over Studies ; Healthy Volunteers ; Meals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety and efficacy of REGENDIL™ infused hair growth promoting product in adult human subject having hair fall complaints (alopecia).
Autorzy:
Merja A; NovoBliss Research Private Limited, Ahmedabad, India.
Patel N; NovoBliss Research Private Limited, Ahmedabad, India.
Patel M; NovoBliss Research Private Limited, Ahmedabad, India.
Patnaik S; Anveya Living Private Limited, Gurugram, India.
Ahmed A; Anveya Living Private Limited, Gurugram, India.
Maulekhi S; Anveya Living Private Limited, Gurugram, India.
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Źródło:
Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Mar; Vol. 23 (3), pp. 938-948. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Alopecia*/diagnosis
Alopecia*/drug therapy
Hair*
Adult ; Humans ; Research Subjects ; Scalp ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hippocampal volume changes after (R,S)-ketamine administration in patients with major depressive disorder and healthy volunteers.
Autorzy:
Evans JW; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA. .
Graves MC; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.
Nugent AC; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.; MEG Core, NIMH, Bethesda, MD, USA.
Zarate CA Jr; Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr., Bldg 10, Rm 7-3335, Bethesda, MD, 20814, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4538. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Depressive Disorder, Major*/diagnostic imaging
Depressive Disorder, Major*/drug therapy
Depressive Disorder, Major*/pathology
Depressive Disorder, Treatment-Resistant*
Ketamine*/pharmacology
Ketamine*/therapeutic use
Humans ; Healthy Volunteers ; Hippocampus/pathology ; Treatment Outcome ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Binding Properties of Antibodies to Z-DNA in the Sera of Normal Healthy Subjects.
Autorzy:
Pisetsky DS; Medical Research Service, Durham Veterans Administration Medical Center, Durham, NC 27705, USA.; Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC 27710, USA.
Gedye MJ; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.
David LA; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC 27710, USA.; Duke Microbiome Center, School of Medicine, Duke University, Durham, NC 27710, USA.
Spencer DM; Medical Research Service, Durham Veterans Administration Medical Center, Durham, NC 27705, USA.; Division of Rheumatology and Immunology, Duke University Medical Center, Durham, NC 27710, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 22; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
DNA, Z-Form*
Animals ; Humans ; Healthy Volunteers ; Antibodies, Antinuclear ; Immunoglobulin G ; Immunoglobulin A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Directed functional connectivity of the default-mode-network of young and older healthy subjects.
Autorzy:
Goelman G; Department of Neurology, Ginges Center of Neurogenetics, Hadassah Hebrew University Medical Center, 91120, Jerusalem, Israel. .; Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. .
Dan R; Department of Neurology, Ginges Center of Neurogenetics, Hadassah Hebrew University Medical Center, 91120, Jerusalem, Israel.; Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
Bezdicek O; Department of Neurology and Center of Clinical Neuroscience, Charles University, Prague, Czech Republic.
Jech R; Department of Neurology and Center of Clinical Neuroscience, Charles University, Prague, Czech Republic.
Ekstein D; Department of Neurology, Ginges Center of Neurogenetics, Hadassah Hebrew University Medical Center, 91120, Jerusalem, Israel.; Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 21; Vol. 14 (1), pp. 4304. Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article
MeSH Terms:
Brain*/diagnostic imaging
Brain Mapping*/methods
Humans ; Aged ; Healthy Volunteers ; Memory, Short-Term ; Aging ; Neural Pathways ; Magnetic Resonance Imaging/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of DMT on mental health outcomes in healthy volunteers.
Autorzy:
Timmermann C; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK. .
Zeifman RJ; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; NYU Langone Center for Psychedelic Medicine, NYU Grosssman School of Medicine, New York, USA.
Erritzoe D; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.
Nutt DJ; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; Centre for Psychiatry, Division of Brain Sciences, Faculty of Medicine, Imperial College, London, UK.
Carhart-Harris RL; Centre for Psychedelic Research, Department of Brain Sciences, Faculty of Medicine, Imperial College London, London, UK.; Psychedelics Division, Neuroscape, Department of Neurology, University of California, San Francisco, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 07; Vol. 14 (1), pp. 3097. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
N,N-Dimethyltryptamine*
Hallucinogens*/pharmacology
Humans ; Psilocybin ; Healthy Volunteers ; Prospective Studies ; Outcome Assessment, Health Care
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacokinetic and safety profiles of mesalazine enema in healthy Chinese subjects: A single- and multiple-dose study.
Autorzy:
Cao Y; Clinical Trial Institute, Huashan Hospital, Fudan University, Shanghai, China.
Wang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Tang X; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Tian Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Yu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Liang H; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Wu J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Chen Y; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Cao G; Clinical Trial Institute, Huashan Hospital, Fudan University, Shanghai, China.; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
Zhang J; Phase I Clinical Research Center, Huashan Hospital, Fudan University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2024 Feb 02; Vol. 19 (2), pp. e0296940. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).
Typ publikacji:
Clinical Trial; Journal Article
MeSH Terms:
Mesalamine*/adverse effects
Tandem Mass Spectrometry*/methods
Humans ; Administration, Oral ; Area Under Curve ; China ; Chromatography, Liquid ; Dose-Response Relationship, Drug ; Healthy Volunteers
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hypoxic pulmonary vasoconstriction does not limit maximal exercise capacity in healthy volunteers breathing 12% oxygen at sea level.
Autorzy:
Talbot NP; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Cheng HY; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Hanstock H; Swedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Smith TG; Centre for Human and Applied Physiological Sciences, King's College London, London, UK.; Guy's and St Thomas' NHS Foundation Trust, London, UK.
Dorrington KL; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Robbins PA; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
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Źródło:
Physiological reports [Physiol Rep] 2024 Feb; Vol. 12 (4), pp. e15944.
Typ publikacji:
Journal Article
MeSH Terms:
Oxygen*
Vasoconstriction*
Humans ; Exercise Tolerance ; Healthy Volunteers ; Pulmonary Artery ; Hypoxia ; Altitude ; Iron/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants.
Autorzy:
Sawant-Basak A; Clinical Pharmacology, Early Clinical Development, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Bergman AJ; Clinical Pharmacology, Early Clinical Development, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Mancuso J; Statistics, Early Clinical Development, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Tripathy S; Clinical Assay Group, Global Product Development, Pfizer Inc., Groton, Connecticut, USA.
Gosset JR; Pharmacokinetics, Dynamics and Metabolism, Medicine Design, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Mendes da Costa L; Pfizer Clinical Research Unit, Brussels, Belgium.
Esler WP; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
Calle RA; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer Inc., Cambridge, Massachusetts, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2024 Feb; Vol. 17 (2), pp. e13687.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*
Pyridines*
Adult ; Humans ; Healthy Volunteers ; Cytochrome P-450 CYP3A ; Enzyme Inhibitors/adverse effects ; Drug Interactions ; Diacylglycerol O-Acyltransferase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Trans-spinal magnetic stimulation induces co-activation of the diaphragm and biceps in healthy subjects.
Autorzy:
Ren MY; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan.
Liou LM; Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.; Department of Neurology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Vinit S; Université Paris-Saclay, UVSQ, Inserm, END-ICAP, Versailles, France.
Lee KZ; Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung, Taiwan.; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan.
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Źródło:
Physiological reports [Physiol Rep] 2024 Feb; Vol. 12 (3), pp. e15941.
Typ publikacji:
Journal Article
MeSH Terms:
Diaphragm*/physiology
Forelimb*
Humans ; Animals ; Male ; Female ; Healthy Volunteers ; Electromyography ; Thoracic Vertebrae ; Magnetic Phenomena ; Electric Stimulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety, tolerability, and pharmacokinetics of a single ascending subcutaneous dose of GSK3772847 in healthy participants.
Autorzy:
Pefani E; GSK Medicines Research Centre, Stevenage, Hertfordshire, UK.
Stone S; GSK, Brentford, Middlesex, UK.
Zhu CQ; GSK, Brentford, Middlesex, UK.
Nunn C; GSK RD Respiratory R&D, Brentford, Middlesex, UK.
Fairman D; GSK Medicines Research Centre, Stevenage, Hertfordshire, UK.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Apr; Vol. 11 (2), pp. e01054.
Typ publikacji:
Randomized Controlled Trial; Journal Article
MeSH Terms:
Healthy Volunteers*
Humans ; Double-Blind Method
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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