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Tytuł:
An experimental medicine study of the effects of simvastatin on emotional processing, reward learning, verbal memory, and inflammation in healthy volunteers.
Autorzy:
De Giorgi R; Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK. .; Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK. .
Quinton AMG; Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.
Waters S; Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.
Cowen PJ; Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.
Harmer CJ; Department of Psychiatry, University of Oxford, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, Oxfordshire, UK.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Aug; Vol. 239 (8), pp. 2635-2645. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Biomedical Research*
Simvastatin*/pharmacology
Double-Blind Method ; Female ; Healthy Volunteers ; Humans ; Inflammation/drug therapy ; Reward ; Verbal Learning
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A randomized, double-blind, placebo controlled, phase 1 study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of LB-102, a selective dopamine D 2/3 /5-HT 7 inhibitor.
Autorzy:
Biernat L; Medpace Clinical Pharmacology LLC, 5355 Medpace Way, Cincinnati, OH, USA.; Eli Lilly and Co, Indianapolis, IN, USA.
Grattan VT; LB Pharmaceuticals Inc, 575 Madison Ave., 10th flr, New York, NY, USA.
Hixon MS; Mark S. Hixon Consulting LLC, 11273 Spitfire Road, San Diego, CA, USA.
Prensky Z; LB Pharmaceuticals Inc, 575 Madison Ave., 10th flr, New York, NY, USA.
Vaino AR; LB Pharmaceuticals Inc, 575 Madison Ave., 10th flr, New York, NY, USA. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Sep; Vol. 239 (9), pp. 3009-3018. Date of Electronic Publication: 2022 Jul 16.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
MeSH Terms:
Dopamine*
Dystonia*
Dose-Response Relationship, Drug ; Double-Blind Method ; Healthy Volunteers ; Humans ; Prolactin ; Serotonin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A single oral dose of citalopram increases interoceptive insight in healthy volunteers.
Autorzy:
Livermore JJA; School of Psychology, University of Sussex, Pevensey Building, Falmer, Brighton, BN1 9QH, UK.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
Holmes CL; School of Psychology, University of Sussex, Pevensey Building, Falmer, Brighton, BN1 9QH, UK.
Moga G; School of Psychology, University of Sussex, Pevensey Building, Falmer, Brighton, BN1 9QH, UK.
Adamatzky K; School of Psychology, University of Sussex, Pevensey Building, Falmer, Brighton, BN1 9QH, UK.
Critchley HD; Department of Neuroscience, Brighton and Sussex Medical School (BSMS), Brighton, UK.; Sackler Centre for Consciousness Science, University of Sussex, Brighton, UK.
Garfinkel SN; Department of Neuroscience, Brighton and Sussex Medical School (BSMS), Brighton, UK.; Sackler Centre for Consciousness Science, University of Sussex, Brighton, UK.; Institute for Cognitive Neuroscience, University College London, London, UK.
Campbell-Meiklejohn D; School of Psychology, University of Sussex, Pevensey Building, Falmer, Brighton, BN1 9QH, UK. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Jul; Vol. 239 (7), pp. 2289-2298. Date of Electronic Publication: 2022 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Awareness*
Citalopram*/pharmacology
Female ; Healthy Volunteers ; Heart Rate/physiology ; Humans ; Male ; Reproducibility of Results ; Serotonin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants.
Autorzy:
Müller F; Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland. .
Kraus E; Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland.
Holze F; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Becker A; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Ley L; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Schmid Y; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Vizeli P; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Liechti ME; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, 4031, Basel, Switzerland.
Borgwardt S; Department of Psychiatry and Psychotherapy, University of Lübeck, 23538, Lübeck, Germany.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Jun; Vol. 239 (6), pp. 1933-1943. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Hallucinogens*/adverse effects
Psilocybin*/pharmacology
Diagnostic and Statistical Manual of Mental Disorders ; Healthy Volunteers ; Humans ; Lysergic Acid Diethylamide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Low-dose LSD and the stream of thought: Increased Discontinuity of Mind, Deep Thoughts and abstract flow.
Autorzy:
Wießner I; Department of Medical Psychology and Psychiatry, School of Medical Sciences, University of Campinas, Rua Tessália Vieira de Camargo 126, Cidade Universitária Zeferino Vaz, Campinas, São Paulo, 13083-887, Brazil. .; Interdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO), School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil. .
Falchi M; Department of Medical Psychology and Psychiatry, School of Medical Sciences, University of Campinas, Rua Tessália Vieira de Camargo 126, Cidade Universitária Zeferino Vaz, Campinas, São Paulo, 13083-887, Brazil.; Interdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO), School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.
Palhano-Fontes F; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Oliveira Maia L; Department of Medical Psychology and Psychiatry, School of Medical Sciences, University of Campinas, Rua Tessália Vieira de Camargo 126, Cidade Universitária Zeferino Vaz, Campinas, São Paulo, 13083-887, Brazil.; Interdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO), School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.
Feilding A; The Beckley Foundation, Beckley Park, Oxford, UK.
Ribeiro S; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Bezerra Mota N; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.; Department of Physics, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Araujo DB; Brain Institute, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Tófoli LF; Department of Medical Psychology and Psychiatry, School of Medical Sciences, University of Campinas, Rua Tessália Vieira de Camargo 126, Cidade Universitária Zeferino Vaz, Campinas, São Paulo, 13083-887, Brazil.; Interdisciplinary Cooperation for Ayahuasca Research and Outreach (ICARO), School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Jun; Vol. 239 (6), pp. 1721-1733. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Hallucinogens*/pharmacology
Lysergic Acid Diethylamide*/pharmacology
Cognition ; Cross-Over Studies ; Healthy Volunteers ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Safety pharmacology of acute LSD administration in healthy subjects.
Autorzy:
Holze F; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Schanzenstrasse 55, CH-4056, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Caluori TV; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Schanzenstrasse 55, CH-4056, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Vizeli P; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Schanzenstrasse 55, CH-4056, Basel, Switzerland.; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
Liechti ME; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Schanzenstrasse 55, CH-4056, Basel, Switzerland. .; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Jun; Vol. 239 (6), pp. 1893-1905. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Hallucinogens*/adverse effects
Lysergic Acid Diethylamide*/adverse effects
Cross-Over Studies ; Double-Blind Method ; Healthy Volunteers ; Heart Rate ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Residual effects of zopiclone on driving performance using a standardized driving simulator among healthy volunteers.
Autorzy:
Iwamoto K; Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8550, Japan. .
Iwata M; Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8550, Japan.
Kambe D; Taisho Pharmaceutical Co., Ltd, Tokyo, 170-8633, Japan.
Imadera Y; Taisho Pharmaceutical Co., Ltd, Tokyo, 170-8633, Japan.
Tachibana N; Taisho Pharmaceutical Co., Ltd, Tokyo, 170-8633, Japan.
Kajiyama Y; Taisho Pharmaceutical Co., Ltd, Tokyo, 170-8633, Japan.
Ando M; Department of Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Aichi, 466-8560, Japan.
Ozaki N; Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8550, Japan.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Mar; Vol. 239 (3), pp. 841-850. Date of Electronic Publication: 2022 Feb 01.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Automobile Driving*
Psychomotor Performance*
Azabicyclo Compounds/pharmacology ; Cross-Over Studies ; Double-Blind Method ; Healthy Volunteers ; Humans ; Hypnotics and Sedatives/pharmacology ; Male ; Piperazines ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of acute alcohol administration on working memory: a systematic review and meta-analysis.
Autorzy:
Spinola S; Department of Psychology, Syracuse University, Syracuse, NY, USA. .; VA Connecticut Healthcare System-West Haven, West Haven, CT, USA. .; Department of Psychiatry, Yale University School of Medicine, New Haven, NY, USA. .
De Vita MJ; Department of Psychology, Syracuse University, Syracuse, NY, USA.; Department of Behavioral Health, Brooke Army Medical Center, San Antonio, TX, USA.
Gilmour CE; Department of Psychology, Syracuse University, Syracuse, NY, USA.; Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA.
Maisto SA; Department of Psychology, Syracuse University, Syracuse, NY, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Mar; Vol. 239 (3), pp. 695-708. Date of Electronic Publication: 2022 Jan 25.
Typ publikacji:
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms:
Executive Function*/physiology
Memory, Short-Term*/physiology
Adult ; Cognition ; Ethanol/adverse effects ; Healthy Volunteers ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
No antidepressant-like acute effects of bright light on emotional information processing in healthy volunteers.
Autorzy:
Kaltenboeck A; Department of Psychiatry, University of Oxford, Oxford, UK. .; Clinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria. .
Ruzickova T; Department of Psychiatry, University of Oxford, Oxford, UK.
Breunhölder V; School of Mathematics and Maxwell Institute for Mathematical Sciences, University of Edinburgh, Edinburgh, UK.
Zghoul T; Department of Psychiatry, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Cowen PJ; Department of Psychiatry, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Harmer CJ; Department of Psychiatry, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Jan; Vol. 239 (1), pp. 277-286. Date of Electronic Publication: 2021 Nov 06.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Emotions*
Phototherapy*
Antidepressive Agents/pharmacology ; Cognition ; Female ; Healthy Volunteers ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional connectivity and cognitive changes after donepezil treatment in healthy participants.
Autorzy:
Péran P; Toulouse NeuroImaging Center (ToNIC), Université de Toulouse, INSERM, UPS, 31024, Toulouse Cedex 3, France. .
Salabert AS; Toulouse NeuroImaging Center (ToNIC), Université de Toulouse, INSERM, UPS, 31024, Toulouse Cedex 3, France.
Dondaine T; Degenerative & Vascular Cognitive Disorders Research Unit, INSERM-Lille University-Lille University Hospital, Lille, France.
Leclerc X; Degenerative & Vascular Cognitive Disorders Research Unit, INSERM-Lille University-Lille University Hospital, Lille, France.
Gros-Dagnac H; Toulouse NeuroImaging Center (ToNIC), Université de Toulouse, INSERM, UPS, 31024, Toulouse Cedex 3, France.
Ranjeva JP; Centre for Metabolic Exploration by Magnetic Resonance (CEMEREM), Aix-Marseille University-CNRS-CRMBM-Timone University Hospital, Marseille, France.
Lopes R; Degenerative & Vascular Cognitive Disorders Research Unit, INSERM-Lille University-Lille University Hospital, Lille, France.
Lanteaume L; Centre for Metabolic Exploration by Magnetic Resonance (CEMEREM), Aix-Marseille University-CNRS-CRMBM-Timone University Hospital, Marseille, France.; Department of Clinical Pharmacology (UPCET), Aix-Marseille University-INSERM-Timone University Hospital, Marseille, France.
Blin O; Centre for Metabolic Exploration by Magnetic Resonance (CEMEREM), Aix-Marseille University-CNRS-CRMBM-Timone University Hospital, Marseille, France.; Department of Clinical Pharmacology (UPCET), Aix-Marseille University-INSERM-Timone University Hospital, Marseille, France.
Thalamas C; Clinical Investigation Center (CIC1436), Toulouse, France.
Bordet R; Degenerative & Vascular Cognitive Disorders Research Unit, INSERM-Lille University-Lille University Hospital, Lille, France.
Payoux P; Toulouse NeuroImaging Center (ToNIC), Université de Toulouse, INSERM, UPS, 31024, Toulouse Cedex 3, France.
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Corporate Authors:
PharmaCog Consortium
Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2021 Nov; Vol. 238 (11), pp. 3071-3082. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Acetylcholinesterase*
Magnetic Resonance Imaging*
Cognition ; Donepezil/pharmacology ; Double-Blind Method ; Healthy Volunteers ; Humans ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers.
Autorzy:
Hofmann C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland. .
Pizzagalli F; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland.; Daiichi Sankyo Development, Gerrards Cross, UK.
Boetsch C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland.
Alberati D; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland.
Ereshefsky L; University of Texas at Austin, Austin, TX, USA.; Parexel International, Los Angeles, CA, USA.
Jhee S; Parexel International, Los Angeles, CA, USA.
Patat A; Biotrial, Rennes, France.
Boutouyrie-Dumont B; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland.; Novartis Institutes for Biomedical Research, Basel, Switzerland.
Martin-Facklam M; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstr. 124, CH - 4070, Basel, Switzerland.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2016 Jul; Vol. 233 (13), pp. 2429-39. Date of Electronic Publication: 2016 May 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Healthy Volunteers*
Glycine/*cerebrospinal fluid
Glycine Plasma Membrane Transport Proteins/*antagonists & inhibitors
Imidazoles/*pharmacology
Neurotransmitter Uptake Inhibitors/*pharmacology
Piperazines/*pharmacology
Sulfones/*pharmacology
Synaptic Transmission/*drug effects
Adult ; Area Under Curve ; Brain/drug effects ; Humans ; Imidazoles/pharmacokinetics ; Male ; Neurotransmitter Uptake Inhibitors/pharmacokinetics ; Piperazines/pharmacokinetics ; Receptors, N-Methyl-D-Aspartate/drug effects ; Schizophrenia/drug therapy ; Sulfones/pharmacokinetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants.
Autorzy:
Galvão-Coelho NL; Laboratory of Hormone Measurement, Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, RN, Brazil. .; Postgraduate Program in Psychobiology and Department of Physiology and Behavior, Federal University of Rio Grande do Norte, Natal, RN, Brazil. .; National Institute of Science and Technology in Translational Medicine, São Paulo, Brazil. .; NICM Health Research Institute, Western Sydney University, Westmead, Australia. .; Departamento de Fisiologia e Comportamento, Universidade Federal do Rio Grande do Norte, Caixa Postal, 1511, CEP: 59078-970, Natal, RN, Brasil. .
Marx W; IMPACT Research Institute, School of Medicine, Deakin University, Geelong, Australia.
Gonzalez M; NICM Health Research Institute, Western Sydney University, Westmead, Australia.
Sinclair J; NICM Health Research Institute, Western Sydney University, Westmead, Australia.
de Manincor M; NICM Health Research Institute, Western Sydney University, Westmead, Australia.
Perkins D; School of Social and Political Science, University of Melbourne, Melbourne, Australia.
Sarris J; NICM Health Research Institute, Western Sydney University, Westmead, Australia.; Professorial Unit, The Melbourne Clinic, Department of Psychiatry, University of Melbourne, Melbourne, Australia.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2021 Feb; Vol. 238 (2), pp. 341-354. Date of Electronic Publication: 2021 Jan 11.
Typ publikacji:
Journal Article; Meta-Analysis; Review
MeSH Terms:
Depressive Disorder, Major/*drug therapy
Hallucinogens/*therapeutic use
Mood Disorders/*drug therapy
Serotonin Receptor Agonists/*therapeutic use
Affect/drug effects ; Banisteriopsis/chemistry ; Depression ; Depressive Disorder, Major/metabolism ; Depressive Disorder, Major/psychology ; Double-Blind Method ; Healthy Volunteers ; Humans ; Lysergic Acid Diethylamide/therapeutic use ; Mood Disorders/metabolism ; Mood Disorders/psychology ; Psilocybin/therapeutic use ; Randomized Controlled Trials as Topic ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers.
Autorzy:
Kirkpatrick MG; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto St., Room 302B, Los Angeles, CA, 90032, USA. .
Goldenson NI; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto St., Room 302B, Los Angeles, CA, 90032, USA.
Kapadia N; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto St., Room 302B, Los Angeles, CA, 90032, USA.
Kahler CW; Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, USA.
de Wit H; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Swift RM; Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, USA.; Providence VA Medical Center, Providence, RI, USA.
McGeary JE; Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, USA.; Providence VA Medical Center, Providence, RI, USA.
Sussman S; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto St., Room 302B, Los Angeles, CA, 90032, USA.
Leventhal AM; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 2001 N. Soto St., Room 302B, Los Angeles, CA, 90032, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2016 Jan; Vol. 233 (1), pp. 89-97. Date of Electronic Publication: 2015 Oct 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Healthy Volunteers*
Individuality*
Affect/*drug effects
Amphetamine/*pharmacology
Emotions/*drug effects
Adult ; Anxiety/psychology ; Arousal/drug effects ; Central Nervous System Stimulants/pharmacology ; Dextroamphetamine/pharmacology ; Female ; Humans ; Male ; Predictive Value of Tests ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CDP-choline and galantamine, a personalized α7 nicotinic acetylcholine receptor targeted treatment for the modulation of speech MMN indexed deviance detection in healthy volunteers: a pilot study.
Autorzy:
Choueiry J; Department of Neuroscience, Faculty of Medicine, University of Ottawa, 1145 Carling Ave, Ottawa, ON, K1Z 7K4, Canada. .; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada. .; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada. .
Blais CM; Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada.
Shah D; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.
Smith D; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada.; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.
Fisher D; Department of Psychology, Faculty of Social Sciences, Mount Saint Vincent University, Halifax, NS, Canada.
Illivitsky V; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.
Knott V; Department of Neuroscience, Faculty of Medicine, University of Ottawa, 1145 Carling Ave, Ottawa, ON, K1Z 7K4, Canada.; Department of Psychiatry, The Royal Ottawa Mental Health Centre, Ottawa, ON, Canada.; Department of Psychology, University of Ottawa Institute of Mental Health Research, Ottawa, ON, Canada.; Institute of Cognitive Science, Carleton University, Ottawa, ON, Canada.; School of Psychology, Faculty of Social Sciences, University of Ottawa, Ottawa, ON, Canada.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Dec; Vol. 237 (12), pp. 3665-3687. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Auditory Perception/*drug effects
Cytidine Diphosphate Choline/*administration & dosage
Galantamine/*administration & dosage
Speech Perception/*drug effects
alpha7 Nicotinic Acetylcholine Receptor/*agonists
Adult ; Auditory Cortex/drug effects ; Auditory Cortex/physiology ; Auditory Perception/physiology ; Cross-Over Studies ; Double-Blind Method ; Drug Delivery Systems/methods ; Electroencephalography/drug effects ; Electroencephalography/methods ; Evoked Potentials, Auditory/drug effects ; Evoked Potentials, Auditory/physiology ; Female ; Healthy Volunteers ; Humans ; Male ; Nootropic Agents/administration & dosage ; Pilot Projects ; Speech/drug effects ; Speech/physiology ; Speech Perception/physiology ; alpha7 Nicotinic Acetylcholine Receptor/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potential shortcomings in current studies on the effect of intranasal oxytocin in Anorexia Nervosa and healthy controls - A systematic review and meta-analysis.
Autorzy:
Hasselbalch KC; Mental Health Center Ballerup, Maglevaenget 32, 2750, Ballerup, Denmark.
Lanng KR; Mental Health Center Ballerup, Maglevaenget 32, 2750, Ballerup, Denmark.
Birkeland M; Mental Health Center Ballerup, Maglevaenget 32, 2750, Ballerup, Denmark.
Sjögren M; Mental Health Center Ballerup, Maglevaenget 32, 2750, Ballerup, Denmark. .; Institute for Clinical Medicine, Copenhagen University, Blegdamsvej 3B, 2200, Copenhagen, Denmark. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Oct; Vol. 237 (10), pp. 2891-2903. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Anorexia Nervosa/*drug therapy
Anorexia Nervosa/*psychology
Oxytocics/*administration & dosage
Oxytocin/*administration & dosage
Administration, Intranasal ; Anxiety/drug therapy ; Anxiety/psychology ; Attentional Bias/drug effects ; Attentional Bias/physiology ; Brain/drug effects ; Brain/physiology ; Fear/drug effects ; Fear/physiology ; Fear/psychology ; Healthy Volunteers ; Humans ; Treatment Outcome
Czasopismo naukowe
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Tytuł:
The effects of acute serotonin challenge on executive planning in patients with obsessive-compulsive disorder (OCD), their first-degree relatives, and healthy controls.
Autorzy:
Lochner C; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa. .
Chamberlain SR; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Cambridgeshire & Peterborough NHS Foundation Trust, Cambridge, UK.
Kidd M; Centre for Statistical Consultation, Department of Statistics and Actuarial Sciences, University of Stellenbosch, Stellenbosch, South Africa.
Taljaard L; SAMRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.
Fineberg NA; National Treatment Service for OCD, Hertfordshire, UK.; University of Hertfordshire, Hertfordshire, UK.
Robbins TW; Department of Psychiatry, University of Cambridge, Cambridge, UK.
Stein DJ; SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, Cape Town, South Africa.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Oct; Vol. 237 (10), pp. 3117-3123. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Executive Function/*drug effects
Family/*psychology
Obsessive-Compulsive Disorder/*drug therapy
Obsessive-Compulsive Disorder/*psychology
Serotonin/*administration & dosage
Selective Serotonin Reuptake Inhibitors/*administration & dosage
Adult ; Attention/drug effects ; Attention/physiology ; Citalopram/administration & dosage ; Cross-Over Studies ; Double-Blind Method ; Executive Function/physiology ; Female ; Healthy Volunteers/psychology ; Humans ; Male ; Mental Status and Dementia Tests ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In an exploratory randomized, double-blind, placebo-controlled, cross-over study, psychoactive doses of intravenous delta-9-tetrahydrocannabinol fail to produce antinociceptive effects in healthy human volunteers.
Autorzy:
Schindler EAD; Neurology Service, MS 127, Veterans Affairs (VA) Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, 06516, USA. .; Department of Neurology, Yale School of Medicine, New Haven, CT, USA. .
Schnakenberg Martin AM; Psychology Service, VA Connecticut Healthcare System, West Haven, CT, USA.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Sewell RA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA.
Ranganathan M; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA.
DeForest A; Neurology Service, MS 127, Veterans Affairs (VA) Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, 06516, USA.; Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Pittman BP; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Perrino A Jr; Anesthesia Service, VA Connecticut Healthcare System, West Haven, CT, USA.; Department of Anesthesia, Yale School of Medicine, New Haven, CT, USA.
D'Souza DC; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Psychiatry Service, VA Connecticut Healthcare System, West Haven, CT, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Oct; Vol. 237 (10), pp. 3097-3107. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Analgesics/*administration & dosage
Dronabinol/*administration & dosage
Euphoria/*drug effects
Pain/*drug therapy
Pain Measurement/*drug effects
Psychotropic Drugs/*administration & dosage
Administration, Intravenous ; Adult ; Cannabinoids/pharmacology ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Euphoria/physiology ; Female ; Healthy Volunteers/psychology ; Humans ; Male ; Pain/diagnosis ; Pain/psychology ; Pain Measurement/methods ; Pain Measurement/psychology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Intrinsic connections between thalamic sub-regions and the lateral prefrontal cortex are differentially impacted by acute methylphenidate.
Autorzy:
Gorka AX; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA. .
Lago TR; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA.
Balderston N; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA.; Center for Neuromodulation in Depression and Stress, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Torrisi S; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA.
Fuchs B; Department of Nutritional Sciences, Penn State University, State College, PA, 16801, USA.
Grillon C; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA.
Ernst M; Section on the Neurobiology of Fear & Anxiety, National Institute of Mental Health, 15K North Drive Rm 300-F, Bethesda, MD, 20892, USA.
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2020 Jun; Vol. 237 (6), pp. 1873-1883. Date of Electronic Publication: 2020 Apr 19.
Typ publikacji:
Journal Article; Randomized Controlled Trial
MeSH Terms:
Magnetic Resonance Imaging/*methods
Memory, Short-Term/*drug effects
Methylphenidate/*administration & dosage
Nerve Net/*drug effects
Prefrontal Cortex/*drug effects
Thalamus/*drug effects
Adult ; Dopamine Uptake Inhibitors/administration & dosage ; Double-Blind Method ; Female ; Healthy Volunteers ; Humans ; Male ; Memory, Short-Term/physiology ; Nerve Net/diagnostic imaging ; Nerve Net/physiology ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/physiology ; Thalamus/diagnostic imaging ; Thalamus/physiology ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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