Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy.
Autorzy:
Shapiro DD; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.; Division of Urology, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA. Zacharias NM; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Tripathi DN; Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas, USA. Karki M; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Bertocchio JP; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Soeung M; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. He R; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Westerman ME; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Gao J; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Rao P; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Lam TNA; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Jonasch E; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Perelli L; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Cheng EH; Human Oncology & Pathogenesis Program and Department of Pathology, Memorial Sloan Kettering Cancer Institute, New York, New York, USA. Carugo A; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Oncology, IRBM Spa, Rome, Italy. HeffernanTP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Translational Research to Advance Therapeutics and Innovation in Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Walker CL; Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas, USA. Genovese G; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Tannir NM; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Karam JA; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Msaouel P; Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas, USA.; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies.
Autorzy:
Shapiro DD; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Soeung M; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Perelli L; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Dondossola E; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Surasi DS; Department of Nuclear Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Tripathi DN; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA. Bertocchio JP; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA. Carbone F; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Starbuck MW; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Van Alstine ML; The Ronin Project, San Mateo, CA 94402, USA. Rao P; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Katz MHG; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Parker NH; Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Shah AY; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Carugo A; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. HeffernanTP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Schadler KL; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Logothetis C; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Walker CL; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA. Wood CG; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Karam JA; Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Draetta GF; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Tannir NM; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Genovese G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Msaouel P; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
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Źródło:
Cancers [Cancers (Basel)] 2021 Nov 30; Vol. 13 (23). Date of Electronic Publication: 2021 Nov 30.
Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.
Autorzy:
Del Poggetto E; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Ho IL; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Balestrieri C; Experimental Hematology Unit, San Raffaele Research Hospital, Milan 20132, Italy.; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan 20132, Italy. Yen EY; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Zhang S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Citron F; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Shah R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Corti D; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Diaferia GR; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan 20139, Italy. Li CY; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. Loponte S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Carbone F; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Hayakawa Y; Department of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY 10032, USA. Valenti G; Department of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY 10032, USA. Jiang S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Sapio L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Jiang H; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Dey P; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Gao S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Deem AK; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Rose-John S; Department of Biochemistry, Christian-Albrechts-Universität zu Kiel, Kiel 24098, Germany. Yao W; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Ying H; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Rhim AD; Department of Gastroenterology Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Genovese G; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. HeffernanTP; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Maitra A; Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Wang TC; Department of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY 10032, USA. Wang L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Draetta GF; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Carugo A; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Natoli G; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan 20139, Italy.; Humanitas University, Pieve Emanuele, Milan 20089, Italy. Viale A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2021 Sep 17; Vol. 373 (6561), pp. eabj0486. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints.
Autorzy:
Molkentine JM; Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. Molkentine DP; Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. Bridges KA; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Xie T; Department of Head and Neck Surgery, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Yang L; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Sheth A; Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA. HeffernanTP; Institute for Applied Cancer Science, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Clump DA; Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. Faust AZ; College of Liberal Arts and Sciences, University of Illinois at Chicago, Chicago, IL, USA. Ferris RL; Department of Otolaryngology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. Myers JN; Department of Head and Neck Surgery, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Frederick MJ; Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA. Mason KA; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Meyn RE; Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Pickering CR; Department of Head and Neck Surgery, MD Anderson Cancer Center, University of Texas, Houston, TX, USA. Skinner HD; Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research.
Autorzy:
Inoue A; Department of Genomic Medicine, UT MD Anderson cancer center, Houston, TX 77054, USA. .; Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan. . Deem AK; Institute for Applied Cancer Science, UT MD Anderson cancer center, Houston, TX 77054, USA. . Kopetz S; Department of Gastrointestinal Medical Oncology, UT MD Anderson cancer center, Houston, TX 77030, USA. .; Moon Shots ProgramTM, UT MD Anderson cancer center, Houston, TX 77030, USA. . HeffernanTP; Moon Shots ProgramTM, UT MD Anderson cancer center, Houston, TX 77030, USA. .; TRACTION platform, UT MD Anderson cancer center, Houston, TX 77054, USA. . Draetta GF; Department of Genomic Medicine, UT MD Anderson cancer center, Houston, TX 77054, USA. .; Moon Shots ProgramTM, UT MD Anderson cancer center, Houston, TX 77030, USA. . Carugo A; Department of Genomic Medicine, UT MD Anderson cancer center, Houston, TX 77054, USA. .; Moon Shots ProgramTM, UT MD Anderson cancer center, Houston, TX 77030, USA. .; TRACTION platform, UT MD Anderson cancer center, Houston, TX 77054, USA. .
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Źródło:
Cancers [Cancers (Basel)] 2019 Sep 06; Vol. 11 (9). Date of Electronic Publication: 2019 Sep 06.
Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.
Autorzy:
Zhan Y; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Kost-Alimova M; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Shi X; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Leo E; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Bardenhagen JP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Shepard HE; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Appikonda S; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Vangamudi B; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Zhao S; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Tieu TN; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Jiang S; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. HeffernanTP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Marszalek JR; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Toniatti C; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Draetta G; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Tyler J; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Barton M; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Jones P; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Palmer WS; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Geck Do MK; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA. Andersen JN; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77230 USA.; XTuit Pharmaceuticals, 700 Main Street, Cambridge, MA 02139 USA.
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Źródło:
Epigenetics & chromatin [Epigenetics Chromatin] 2015 Sep 21; Vol. 8, pp. 37. Date of Electronic Publication: 2015 Sep 21 (Print Publication: 2015).
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Autorzy:
Viale A; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [3]. Pettazzoni P; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [3]. Lyssiotis CA; Department of Medicine, Weill Cornell Medical College, New York, New York 10065, USA. Ying H; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Sánchez N; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Marchesini M; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Carugo A; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [3] Department of Experimental Oncology, European Institute of Oncology, Milan 20139, Italy. Green T; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Seth S; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Giuliani V; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Kost-Alimova M; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Muller F; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Colla S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Nezi L; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Genovese G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Deem AK; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Kapoor A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Yao W; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Brunetto E; Pathology Unit, San Raffaele Scientific Institute, Milan 20132, Italy. Kang Y; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Yuan M; Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA. Asara JM; Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA. Wang YA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. HeffernanTP; Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Kimmelman AC; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA. Wang H; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Fleming JB; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Cantley LC; Department of Medicine, Weill Cornell Medical College, New York, New York 10065, USA. DePinho RA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Draetta GF; 1] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
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Źródło:
Nature [Nature] 2014 Oct 30; Vol. 514 (7524), pp. 628-32. Date of Electronic Publication: 2014 Aug 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome.
Autorzy:
Wardwell-Ozgo J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Dogruluk T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Gifford A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Zhang Y; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA. HeffernanTP; Institute for Applied Cancer Science, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. van Doorn R; Department of Dermatology; Leiden University Medical Center, Leiden, The Netherlands. Creighton CJ; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA. Chin L; 1] Institute for Applied Cancer Science, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA [2] Department of Genomic Medicine, Houston, TX, USA. Scott KL; 1] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA [2] Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.
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Źródło:
Oncogene [Oncogene] 2014 Feb 20; Vol. 33 (8), pp. 1017-26. Date of Electronic Publication: 2013 Feb 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Validation Study
Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.
Autorzy:
Simpson DA; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina, CB 7295, Chapel Hill, NC 27599, USA. />Livanos E HeffernanTP Kaufmann WK
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Źródło:
Journal of carcinogenesis [J Carcinog] 2005 Oct 06; Vol. 4, pp. 18. Date of Electronic Publication: 2005 Oct 06.
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