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Tytuł:
Comparative virulence of diverse Coxiella burnetii strains.
Autorzy:
Long CM; a Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases , National Institutes of Health , Hamilton , MT , USA.
Beare PA; a Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases , National Institutes of Health , Hamilton , MT , USA.
Cockrell DC; a Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases , National Institutes of Health , Hamilton , MT , USA.
Larson CL; a Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases , National Institutes of Health , Hamilton , MT , USA.
Heinzen RA; a Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases , National Institutes of Health , Hamilton , MT , USA.
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Źródło:
Virulence [Virulence] 2019 Dec; Vol. 10 (1), pp. 133-150.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Coxiella burnetii/*pathogenicity
Q Fever/*pathology
Virulence Factors/*genetics
Animals ; CD4-Positive T-Lymphocytes/immunology ; Coxiella burnetii/genetics ; Disease Models, Animal ; Female ; Genome, Bacterial ; Guinea Pigs ; Q Fever/immunology ; Spleen/microbiology ; Virulence/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Actin polymerization in the endosomal pathway, but not on the Coxiella-containing vacuole, is essential for pathogen growth.
Autorzy:
Miller HE; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Larson CL; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2018 Apr 18; Vol. 14 (4), pp. e1007005. Date of Electronic Publication: 2018 Apr 18 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Actins/*metabolism
Coxiella burnetii/*pathogenicity
Endosomes/*microbiology
Microfilament Proteins/*physiology
Q Fever/*microbiology
Vacuoles/*microbiology
Vesicular Transport Proteins/*physiology
Animals ; Endosomes/metabolism ; Golgi Apparatus/metabolism ; Golgi Apparatus/microbiology ; Humans ; Mice ; Mice, Knockout ; Microfilament Proteins/metabolism ; Polymerization ; Protein Transport ; Q Fever/metabolism ; Vacuoles/metabolism ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Coxiella burnetii phospholipase A homolog pldA is required for optimal growth in macrophages and developmental form lipid remodeling.
Autorzy:
Stead CM; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.; Department of Chemistry, New Mexico Highlands University, Las Vegas, New Mexico, USA.
Cockrell DC; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Beare PA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Miller HE; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA. .
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Źródło:
BMC microbiology [BMC Microbiol] 2018 Apr 16; Vol. 18 (1), pp. 33. Date of Electronic Publication: 2018 Apr 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Lipid Metabolism*
Bacterial Outer Membrane Proteins/*metabolism
Coxiella burnetii/*enzymology
Coxiella burnetii/*growth & development
Macrophages/*microbiology
Membrane Lipids/*metabolism
Phospholipases A1/*metabolism
Bacterial Outer Membrane Proteins/genetics ; Bacterial Proteins/metabolism ; Coxiella burnetii/genetics ; Coxiella burnetii/pathogenicity ; Cytoplasm/microbiology ; Escherichia coli/metabolism ; Fatty Acids/metabolism ; Genes, Bacterial/genetics ; Humans ; Open Reading Frames/genetics ; Phospholipases A1/genetics ; Q Fever/microbiology ; Sequence Deletion ; THP-1 Cells ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation.
Autorzy:
Beare PA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Jeffrey BM; Bioinformatics and Computational Biosciences Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Long CM; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Martens CM; Research Technologies Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2018 Feb 26; Vol. 14 (3), pp. e1006922. Date of Electronic Publication: 2018 Feb 26 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Genetic Variation*
Virulence*
Bacterial Proteins/*genetics
Coxiella burnetii/*genetics
Lipopolysaccharides/*metabolism
Q Fever/*microbiology
Virulence Factors/*genetics
Coxiella burnetii/pathogenicity ; Gene Expression Regulation, Bacterial ; Genome, Bacterial ; Humans ; Q Fever/genetics ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages.
Autorzy:
Cockrell DC; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Long CM; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Robertson SJ; Innate Immunity and Pathogenesis Unit, Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Shannon JG; Plague Section, Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Miller HE; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Myers L; Retroviral Immunology Section, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Larson CL; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Starr T; Salmonella-Host Cell Interactions Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Beare PA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
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Źródło:
PloS one [PLoS One] 2017 Mar 09; Vol. 12 (3), pp. e0173528. Date of Electronic Publication: 2017 Mar 09 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow/*microbiology
Coxiella burnetii/*growth & development
Macrophages/*microbiology
Q Fever/*microbiology
Animals ; Bone Marrow/metabolism ; Cells, Cultured ; Colony-Stimulating Factors/metabolism ; Coxiella burnetii/pathogenicity ; Female ; Macrophages/cytology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Q Fever/metabolism ; Q Fever/pathology ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L.
Autorzy:
Justis AV; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Hansen B; Research Technology Branch, National Institutes of Health, Hamilton, MT, USA.
Beare PA; Laboratory of Bacteriology, Rocky Mountain Labs, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
King KB; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
Heinzen RA; Laboratory of Bacteriology, Rocky Mountain Labs, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Gilk SD; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA.
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Źródło:
Cellular microbiology [Cell Microbiol] 2017 Jan; Vol. 19 (1). Date of Electronic Publication: 2016 Jul 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Host-Pathogen Interactions*
Coxiella burnetii/*pathogenicity
Endoplasmic Reticulum/*metabolism
Receptors, Steroid/*metabolism
Vacuoles/*metabolism
Vacuoles/*microbiology
Animals ; Bacterial Proteins ; Cell Line ; Humans ; Microscopy, Electron
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Vasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages.
Autorzy:
Colonne PM; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Winchell CG; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Graham JG; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Onyilagha FI; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
MacDonald LJ; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Doeppler HR; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America.
Storz P; Department of Cancer Biology, Mayo Clinic, Jacksonville, Florida, United States of America.
Kurten RC; Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.; Arkansas Children's Hospital Research Institute, Little Rock, Arkansas, United States of America.
Beare PA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Voth DE; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2016 Oct 06; Vol. 12 (10), pp. e1005915. Date of Electronic Publication: 2016 Oct 06 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Cell Adhesion Molecules/*metabolism
Host-Pathogen Interactions/*physiology
Macrophages, Alveolar/*metabolism
Macrophages, Alveolar/*microbiology
Microfilament Proteins/*metabolism
Phosphoproteins/*metabolism
Q Fever/*metabolism
Coxiella burnetii ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Enzyme Activation/physiology ; Gene Knockdown Techniques ; Humans ; Immunoblotting ; Immunoprecipitation ; Microscopy, Confocal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Transcriptional Profiling of Coxiella burnetii Reveals Extensive Cell Wall Remodeling in the Small Cell Variant Developmental Form.
Autorzy:
Sandoz KM; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Popham DL; Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, United States of America.
Beare PA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Sturdevant DE; Genomics Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Hansen B; Electron Microscopy Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Nair V; Electron Microscopy Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Heinzen RA; Coxiella Pathogenesis Section, Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Feb 24; Vol. 11 (2), pp. e0149957. Date of Electronic Publication: 2016 Feb 24 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Gene Expression Regulation, Bacterial*
Oxidative Stress*
Transcriptome*
Cell Wall/*metabolism
Coxiella burnetii/*metabolism
Q Fever/*metabolism
Animals ; Cell Wall/genetics ; Chlorocebus aethiops ; Coxiella burnetii/genetics ; Coxiella burnetii/pathogenicity ; Gene Expression Profiling ; Humans ; Q Fever/genetics ; Vero Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sec-mediated secretion by Coxiella burnetii.
Autorzy:
Stead CM; Coxiella Pathogenesis Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. .
Omsland A
Beare PA
Sandoz KM
Heinzen RA
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Źródło:
BMC microbiology [BMC Microbiol] 2013 Oct 05; Vol. 13, pp. 222. Date of Electronic Publication: 2013 Oct 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Metabolic Networks and Pathways*
Bacterial Proteins/*metabolism
Coxiella burnetii/*metabolism
Animals ; Bacterial Proteins/genetics ; Chlorocebus aethiops ; Computational Biology ; Culture Media/chemistry ; Mass Spectrometry ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Protein Sorting Signals ; Protein Transport ; Sequence Deletion ; Vero Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bacterial colonization of host cells in the absence of cholesterol.
Autorzy:
Gilk SD; Coxiella Pathogenesis Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Cockrell DC
Luterbach C
Hansen B
Knodler LA
Ibarra JA
Steele-Mortimer O
Heinzen RA
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Źródło:
PLoS pathogens [PLoS Pathog] 2013 Jan; Vol. 9 (1), pp. e1003107. Date of Electronic Publication: 2013 Jan 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Host-Pathogen Interactions*
Bacteria/*pathogenicity
Bacterial Infections/*metabolism
Cholesterol/*deficiency
Animals ; Bacteria/growth & development ; Bacterial Physiological Phenomena ; Cells, Cultured ; Cholesterol/metabolism ; Colony Count, Microbial ; Embryo, Mammalian/cytology ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Fibroblasts/microbiology ; Membrane Microdomains/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bringing culture to the uncultured: Coxiella burnetii and lessons for obligate intracellular bacterial pathogens.
Autorzy:
Omsland A; Host-Parasite Interactions Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Hackstadt T
Heinzen RA
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Źródło:
PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (9), pp. e1003540. Date of Electronic Publication: 2013 Sep 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:
Coxiella burnetii/*growth & development
Bacteriological Techniques/methods ; Coxiella burnetii/cytology ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 28

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