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Wyszukujesz frazę ""Hela Cells"" wg kryterium: Temat


Tytuł :
Wealthy funder pays reparations for use of HeLa cells.
Autorzy :
Witze A
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Źródło :
Nature [Nature] 2020 Nov; Vol. 587 (7832), pp. 20-21.
Typ publikacji :
Historical Article; News
MeSH Terms :
HeLa Cells*
Racism*/economics
Racism*/history
Racism*/prevention & control
Academies and Institutes/*economics
Foundations/*economics
Female ; Financing, Organized/economics ; History, 20th Century ; History, 21st Century ; Humans ; Syphilis/history ; United States
Periodyk
Tytuł :
3D profilometry and cell viability studies for drug response screening.
Autorzy :
Morán MC; Departament de Bioquímica i Fisiologia, Secció de Fisiologia - Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Avda. Joan XXIII, 27-31, 08028 Barcelona, Spain; Institut de Nanociència i Nanotecnologia - IN(2)UB, Universitat de Barcelona, Avda. Diagonal, 645, 08028 Barcelona, Spain. Electronic address: .
Cirisano F; CNR-ICMATE Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia, via De Marini, 6, 16149 Genova, Italy.
Ferrari M; Institut de Nanociència i Nanotecnologia - IN(2)UB, Universitat de Barcelona, Avda. Diagonal, 645, 08028 Barcelona, Spain; CNR-ICMATE Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia, via De Marini, 6, 16149 Genova, Italy. Electronic address: .
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Źródło :
Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2020 Oct; Vol. 115, pp. 111142. Date of Electronic Publication: 2020 May 30.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Fluorouracil/*pharmacology
HeLa Cells/*cytology
Imaging, Three-Dimensional/*methods
Swiss 3T3 Cells/*cytology
Animals ; Cell Line ; Cell Size/drug effects ; Cell Survival/drug effects ; Fluorouracil/chemistry ; HeLa Cells/drug effects ; Humans ; Mice ; Nanoparticles ; Swiss 3T3 Cells/drug effects
Czasopismo naukowe
Tytuł :
A reporter cell line for real-time imaging of autophagy and apoptosis.
Autorzy :
Lupitha SS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Chandrasekhar L; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Varadarajan SN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Jayaprasad AG; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Chandrasekharan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Patil SN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Mini M; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Pillai PR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India.
Santhoshkumar TR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (Research Centre, University of Kerala), Poojappura, Thycaud P.O., Thiruvananthapuram, Kerala, 695014, India. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2020 Jun 15; Vol. 326, pp. 23-30. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Autophagy/*drug effects
Cell Line, Tumor/*drug effects
Drug Evaluation, Preclinical/*methods
Genes, Reporter/*drug effects
Green Fluorescent Proteins/*drug effects
HeLa Cells/*drug effects
Apoptosis/physiology ; Autophagy/physiology ; Cell Line, Tumor/physiology ; Genes, Reporter/physiology ; Green Fluorescent Proteins/physiology ; HeLa Cells/physiology ; Humans
Czasopismo naukowe
Tytuł :
[MiR-600 suppresses HeLa cell proliferation by inhibiting hypoxia-inducible factor-1 α signaling pathway].
Autorzy :
Zhou X; Department of Obstetrics and Gynecology, Chengdu Second People's Hospital, Chengdu 610000, China.
Deng J; Department of Obstetrics and Gynecology, First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, China.
Zhang W; Department of Respiratory Medicine, First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, China.
Wang J; Department of Rheumatology Medicine, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
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Źródło :
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2021 Feb 25; Vol. 41 (2), pp. 210-215.
Typ publikacji :
Journal Article
MeSH Terms :
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
MicroRNAs*/genetics
Cell Proliferation ; HeLa Cells ; Humans ; Signal Transduction ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł :
Preparation and characterization of folic acid conjugated sulfated polysaccharides on NK cell activation and cellular uptake in HeLa cells.
Autorzy :
Li C; College of Food Science, Heilongjiang Bayi Agricultural University, Daqing, 163319, China; Department of Marine Food Science and Technology, Gangneung-Wonju National University, 120 Gangneung, Gangwon, 210-702, Republic of Korea.
Palanisamy S; Department of Marine Food Science and Technology, Gangneung-Wonju National University, 120 Gangneung, Gangwon, 210-702, Republic of Korea; East Coast Life Sciences Institute, Gangneung-Wonju National University, 120 Gangneung, Gangwon 210-720, Republic of Korea.
Talapphet N; Department of Marine Food Science and Technology, Gangneung-Wonju National University, 120 Gangneung, Gangwon, 210-702, Republic of Korea.
Cho M; National Institute for Korean Medicine Development, Gyeongsan 38540, Republic of Korea. Electronic address: .
You S; Department of Marine Food Science and Technology, Gangneung-Wonju National University, 120 Gangneung, Gangwon, 210-702, Republic of Korea; East Coast Life Sciences Institute, Gangneung-Wonju National University, 120 Gangneung, Gangwon 210-720, Republic of Korea. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Feb 15; Vol. 254, pp. 117250. Date of Electronic Publication: 2020 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Folic Acid/*chemistry
Polysaccharides/*chemistry
Cell Line ; Cell Survival/drug effects ; Drug Delivery Systems ; Folic Acid Transporters/metabolism ; HeLa Cells ; Humans ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Lymphocyte Activation/drug effects ; MAP Kinase Signaling System/drug effects ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Polysaccharides/pharmacokinetics ; Polysaccharides/toxicity ; Spectroscopy, Fourier Transform Infrared ; Sulfuric Acid Esters/chemistry
Czasopismo naukowe
Tytuł :
Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy.
Autorzy :
Cao S; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
Shao J; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
Wu H; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
Song S; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
De Martino MT; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
Pijpers IAB; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands.
Friedrich H; Center for Multiscale Electron Microscopy (CMEM) and Department of Chemical Engineering and Chemistry, Physical Chemistry, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, MB, Eindhoven, The Netherlands.
Abdelmohsen LKEA; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands. .
Williams DS; Department of Chemistry, College of Science, Swansea University, Swansea, UK. .
van Hest JCM; Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, MB, Eindhoven, The Netherlands. .
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Źródło :
Nature communications [Nat Commun] 2021 Apr 06; Vol. 12 (1), pp. 2077. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Light*
Phototherapy*
Nanoparticles/*chemistry
Cell Line, Tumor ; Gold/chemistry ; HeLa Cells ; Humans ; Motion ; Nanoparticles/ultrastructure ; Polymers/chemistry
Czasopismo naukowe
Tytuł :
Chemical composition, cytotoxicity, and antibacterial activity of propolis from Africanized honeybees and three different Meliponini species.
Autorzy :
Surek M; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil; Laboratory of Physiology and Cell Signalling, Department of Clinical Analysis, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
Fachi MM; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
de Fátima Cobre A; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
de Oliveira FF; Laboratory of Bionomy, Biogeography and Insect Systematics (BIOSIS), Federal University of Bahia, St. Barão de Jeremoabo, S/N, 40170-115, Salvador, BA, Brazil.
Pontarolo R; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
Crisma AR; Laboratory of Physiology and Cell Signalling, Department of Clinical Analysis, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
de Souza WM; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil.
Felipe KB; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil; Laboratory of Physiology and Cell Signalling, Department of Clinical Analysis, Federal University of Paraná, Av. Prefeito Lothário Meissner 632, 80210-170, Curitiba, PR, Brazil. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 06; Vol. 269, pp. 113662. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Anti-Bacterial Agents/*pharmacology
Antibiotics, Antineoplastic/*chemistry
Antibiotics, Antineoplastic/*pharmacology
Propolis/*chemistry
Propolis/*pharmacology
Animals ; Anti-Bacterial Agents/isolation & purification ; Antibiotics, Antineoplastic/isolation & purification ; Bees ; Cell Survival/drug effects ; Cell Survival/physiology ; Chromatography, High Pressure Liquid/methods ; Dose-Response Relationship, Drug ; HeLa Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Propolis/isolation & purification ; Tandem Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Tiliacora racemosa leaves induce oxidative stress mediated DNA damage leading to G2/M phase arrest and apoptosis in cervical cancer cells SiHa.
Autorzy :
Pal A; Cell Biology Laboratory, Department of Botany, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, India.
Sengupta S; Cell Biology Laboratory, Department of Botany, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, India.
Kundu R; Cell Biology Laboratory, Department of Botany, University of Calcutta, 35, Ballygunge Circular Road, Kolkata, 700019, India. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 06; Vol. 269, pp. 113686. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
Menispermaceae*
Antineoplastic Agents, Phytogenic/*therapeutic use
Cell Division/*drug effects
DNA Damage/*drug effects
G2 Phase/*drug effects
Oxidative Stress/*drug effects
Uterine Cervical Neoplasms/*metabolism
Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Cell Division/physiology ; Cell Survival/drug effects ; Cell Survival/physiology ; DNA Damage/physiology ; Dose-Response Relationship, Drug ; Female ; G2 Phase/physiology ; HEK293 Cells ; HeLa Cells ; Humans ; Oxidative Stress/physiology ; Plant Leaves ; Uterine Cervical Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.
Autorzy :
Shen Y; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Zhang ZC; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China. Electronic address: .
Cheng S; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Liu A; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Zuo J; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Xia S; Institute of Neuroscience, Soochow University, Suzhou 215000, China.
Liu X; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Liu W; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China.
Jia Z; Neurosciences and Mental Health Program, Hospital for Sick Children, University of Toronto, Toronto, ON M5S 1A1, Canada.
Xie W; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China.
Han J; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing 210096, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China; Department of Neurology, Affiliated ZhongDa Hospital, Institute of Neuropsychiatry, Southeast University, Nanjing, Jiangsu 210009, China. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Apr 01; Vol. 81 (7), pp. 1425-1438.e10. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Long-Term Synaptic Depression*
Peptide Chain Elongation, Translational*
DNA-Binding Proteins/*metabolism
Hippocampus/*metabolism
Peptide Elongation Factor 2/*metabolism
Receptors, Metabotropic Glutamate/*biosynthesis
Animals ; DNA-Binding Proteins/genetics ; HEK293 Cells ; HeLa Cells ; Humans ; Mice ; Mice, Knockout ; Peptide Elongation Factor 2/genetics ; Phosphorylation ; Receptors, Metabotropic Glutamate/genetics
Czasopismo naukowe
Tytuł :
Identification of the internal ribosome entry sites in the 5'‑untranslated region of the c‑fos gene.
Autorzy :
Li H; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Chen Y; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Zhang J; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Lin Y; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Yang Z; Division of Biology, Kansas State University, Manhattan, KS 66506, USA.
Tan J; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
Qiao W; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, P.R. China.
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Źródło :
International journal of molecular medicine [Int J Mol Med] 2021 Apr; Vol. 47 (4), pp. 1. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
5' Untranslated Regions/*genetics
Gene Expression Regulation/*genetics
Genes, fos/*genetics
Internal Ribosome Entry Sites/*genetics
Proto-Oncogene Proteins c-fos/*genetics
Autoantigens/metabolism ; Base Sequence/genetics ; Cell Line, Tumor ; Enterovirus A, Human/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Protein Biosynthesis/genetics ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Rhabdomyosarcoma/metabolism ; Rhabdomyosarcoma/virology ; Ribonucleoproteins/metabolism ; Ribosomes/metabolism ; Transcription Factor AP-1/genetics ; Transcription, Genetic/genetics
Czasopismo naukowe
Tytuł :
Lactoferrin affects rhinovirus B-14 entry into H1-HeLa cells.
Autorzy :
Denani CB; Instituto de Tecnologia em Imunobiológicos, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Real-Hohn A; Center for Medical Biochemistry, Max Perutz Laboratories, Medical University of Vienna, Vienna Biocenter, Vienna, Austria. .
de Carvalho CAM; Departamento de Patologia, Centro de Ciências Biológicas e da Saúde, Universidade do Estado do Pará, Belém, PA, Brazil.; Centro Universitário Metropolitano da Amazônia, Instituto Euro-Americano de Educação, Ciência e Tecnologia, Belém, PA, Brazil.
Gomes AMO; Programa de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem, Rio de Janeiro, RJ, Brazil.
Gonçalves RB; Departamento de Bioquímica, Instituto Biomédico, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
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Źródło :
Archives of virology [Arch Virol] 2021 Apr; Vol. 166 (4), pp. 1203-1211. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*pharmacology
Enterovirus/*drug effects
Lactoferrin/*pharmacology
Virus Internalization/*drug effects
Antiviral Agents/metabolism ; Cell Survival/drug effects ; Cytopathogenic Effect, Viral/drug effects ; Enterovirus/physiology ; Enterovirus Infections/virology ; HeLa Cells ; Humans ; Lactoferrin/metabolism ; Virus Attachment/drug effects
SCR Organism :
Rhinovirus B
Czasopismo naukowe
Tytuł :
A novel and distinctive mode of cell death revealed by using non-thermal atmospheric pressure plasma: The involvements of reactive oxygen species and the translation inhibitor Pdcd4.
Autorzy :
Eto K; Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Japan. Electronic address: .
Ishinada C; Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Japan.
Suemoto T; Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Japan.
Hyakutake K; Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Japan.
Tanaka H; Institute of Innovation for Future Society, Nagoya University, Japan.
Hori M; Institute of Innovation for Future Society, Nagoya University, Japan.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Apr 01; Vol. 338, pp. 109403. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Biosynthesis*/drug effects
Plasma Gases/*pharmacology
Reactive Oxygen Species/*metabolism
Apoptosis Regulatory Proteins ; Cell Death/drug effects ; HeLa Cells ; Humans ; RNA-Binding Proteins
Czasopismo naukowe
Tytuł :
Saniculamin C, a new flavonoid from Sanicula lamelligera .
Autorzy :
Liu WH; General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China.
Huang DH; Traditional Chinese Medicine Hospital of Guangdong Province, Guangzhou 510120, China.
Gan K; Traditional Chinese Medicine Hospital of Guangdong Province, Guangzhou 510120, China.
Wang ST; The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China.
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Źródło :
Journal of Asian natural products research [J Asian Nat Prod Res] 2021 Apr; Vol. 23 (4), pp. 379-384. Date of Electronic Publication: 2020 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*/pharmacology
Sanicula*
Flavonoids/pharmacology ; HeLa Cells ; Humans ; Molecular Structure
Czasopismo naukowe
Tytuł :
UXT chaperone prevents proteotoxicity by acting as an autophagy adaptor for p62-dependent aggrephagy.
Autorzy :
Yoon MJ; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Choi B; Department of Anatomy, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim EJ; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Ohk J; Department of Anatomy, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yang C; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Choi YG; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Lee J; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Kang C; School of Biological Sciences, Seoul National University, Seoul, Republic of Korea.
Song HK; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Kim YK; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Woo JS; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Cho Y; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Choi EJ; Department of Life Sciences, Korea University, Seoul, Republic of Korea.
Jung H; Department of Anatomy, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea. .
Kim C; Department of Life Sciences, Korea University, Seoul, Republic of Korea. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 29; Vol. 12 (1), pp. 1955. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Aggregates*/drug effects
Autophagy/*genetics
Cell Cycle Proteins/*genetics
Molecular Chaperones/*genetics
Sequestosome-1 Protein/*genetics
Superoxide Dismutase-1/*genetics
Animals ; Autophagy/drug effects ; Cell Cycle Proteins/metabolism ; Ganglia, Spinal/cytology ; Ganglia, Spinal/metabolism ; Gene Expression Regulation ; Genes, Reporter ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Leupeptins/pharmacology ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Molecular Chaperones/metabolism ; Motor Neurons/cytology ; Motor Neurons/drug effects ; Motor Neurons/metabolism ; Primary Cell Culture ; Proteasome Endopeptidase Complex/drug effects ; Proteasome Endopeptidase Complex/metabolism ; Protein Folding/drug effects ; Sequestosome-1 Protein/metabolism ; Signal Transduction ; Superoxide Dismutase-1/metabolism ; Transgenes ; Xenopus laevis
Czasopismo naukowe
Tytuł :
TDP-43 and PINK1 mediate CHCHD10 mutation-induced defects in Drosophila and in vitro.
Autorzy :
Baek M; Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, Duluth, MN, USA.
Choe YJ; Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, Duluth, MN, USA.
Bannwarth S; Inserm U1081, CNRS UMR7284, IRCAN, Université Côte d'Azur, CHU de Nice, Nice, France.
Kim J; Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, Duluth, MN, USA.
Maitra S; Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, Duluth, MN, USA.
Dorn GW 2nd; Center for Pharmacogenomics, Washington University School of Medicine, St. Louis, MO, USA.
Taylor JP; Howard Hughes Medical Institute and Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Paquis-Flucklinger V; Inserm U1081, CNRS UMR7284, IRCAN, Université Côte d'Azur, CHU de Nice, Nice, France.
Kim NC; Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, Duluth, MN, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1924. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Amyotrophic Lateral Sclerosis/*genetics
DNA-Binding Proteins/*genetics
Drosophila Proteins/*genetics
Frontotemporal Dementia/*genetics
Mitochondrial Proteins/*genetics
Protein-Serine-Threonine Kinases/*genetics
Amino Acid Sequence ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Animals, Genetically Modified ; Cell Line, Tumor ; DNA-Binding Proteins/metabolism ; Drosophila Proteins/metabolism ; Frontotemporal Dementia/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Microscopy, Confocal ; Mitochondria/genetics ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Protein Transport/genetics ; Protein-Serine-Threonine Kinases/metabolism ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Cardiac macrophages prevent sudden death during heart stress.
Autorzy :
Sugita J; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Fujiu K; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .; Department of Advanced Cardiology, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. .; PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama, 332-0012, Japan. .
Nakayama Y; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Matsubara T; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Matsuda J; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Oshima T; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Liu Y; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Maru Y; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Hasumi E; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Kojima T; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Seno H; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Asano K; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Ishijima A; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Tomii N; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Yamazaki M; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Kudo F; Department of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan.
Sakuma I; Medical Device Development and Regulation Research Center, Department of Bioengineering/Department of Precision Engineering, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Nagai R; Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi-ken, Tochigi, 329-0498, Japan.
Manabe I; Department of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba, 260-8670, Japan. .
Komuro I; Department of Cardiovascular Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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Źródło :
Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1910. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amphiregulin/*physiology
Arrhythmias, Cardiac/*complications
Death, Sudden, Cardiac/*prevention & control
Macrophages/*physiology
Myocardium/*metabolism
Amphiregulin/metabolism ; Animals ; Animals, Newborn ; Cells, Cultured ; Death, Sudden, Cardiac/etiology ; Female ; Gap Junctions/physiology ; HeLa Cells ; Humans ; Macrophages/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Myocardium/cytology ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/physiology ; Receptors, Adrenergic, beta/metabolism
Czasopismo naukowe
Tytuł :
Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells.
Autorzy :
Bonsergent E; Institut Curie, PSL Research University, INSERM U932, Paris, France.; Université de Paris, INSERM, CNRS UMR 7057, Paris, France.
Grisard E; Institut Curie, PSL Research University, INSERM U932, Paris, France.
Buchrieser J; Institut Pasteur, Virus and Immunity Unit, Department of Virology, CNRS, UMR 3569, Paris, France.
Schwartz O; Institut Pasteur, Virus and Immunity Unit, Department of Virology, CNRS, UMR 3569, Paris, France.
Théry C; Institut Curie, PSL Research University, INSERM U932, Paris, France.
Lavieu G; Institut Curie, PSL Research University, INSERM U932, Paris, France. .; Université de Paris, INSERM, CNRS UMR 7057, Paris, France. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 25; Vol. 12 (1), pp. 1864. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Differentiation/*metabolism
Biological Transport/*physiology
Cell Communication/*physiology
Extracellular Vesicles/*metabolism
Cell Line, Tumor ; Cytosol/metabolism ; Enzyme Inhibitors/pharmacology ; Fluorescent Dyes/metabolism ; HEK293 Cells ; HeLa Cells ; Humans ; Luciferases/metabolism ; Macrolides/pharmacology ; Membrane Fusion/physiology
Czasopismo naukowe

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