Anti-seizure effects of JNJ-54175446 in the intra-amygdala kainic acid model of drug-resistant temporal lobe epilepsy in mice.
Autorzy:
Mamad O; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Heiland M; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Lindner AU; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Hill TDM; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Ronroy RM; Division of Population Health Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Rentrup K; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Sanz-Rodriguez A; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Langa E; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. HellerJP; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; School of Biotechnology, Dublin City University, Dublin, Ireland. Moreno O; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), San Sebastián, Spain. Llop J; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), San Sebastián, Spain. Bhattacharya A; Neuroscience, Janssen Pharmaceutical Research and Development, LLC, San Diego, CA, United States. Palmer JA; Neuroscience, Janssen Pharmaceutical Research and Development, LLC, San Diego, CA, United States. Ceusters M; Neuroscience, Janssen Pharmaceutical Research and Development, Janssen Pharmaceutica NV, Beerse, Belgium. Engel T; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Henshall DC; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
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Frontiers in pharmacology [Front Pharmacol] 2024 Jan 08; Vol. 14, pp. 1308478. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2023).
Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy.
Autorzy:
Brindley E; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Heiland M; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Mooney C; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; School of Computer Science, University College Dublin, Dublin, Ireland. Diviney M; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Mamad O; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Hill TDM; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Yan Y; Interdisciplinary Nanoscience Centre (iNANO) and Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark. Venø MT; Interdisciplinary Nanoscience Centre (iNANO) and Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark.; Omiics ApS, Aarhus, Denmark. Reschke CR; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Batool A; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Langa E; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Sanz-Rodriguez A; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. HellerJP; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; School of Biotechnology, Dublin City University, Dublin, Ireland. Morris G; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom.; Division of Neuroscience, Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom. Conboy K; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland. Kjems J; Interdisciplinary Nanoscience Centre (iNANO) and Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. Brennan GP; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; School of Biomolecular and Biomedical Sciences, Conway Institute, University College Dublin, Dublin, Ireland. Henshall DC; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.; FutureNeuro SFI Research Centre, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
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Frontiers in molecular neuroscience [Front Mol Neurosci] 2023 Sep 22; Vol. 16, pp. 1230942. Date of Electronic Publication: 2023 Sep 22 (Print Publication: 2023).
Human neutrophils communicate remotely via calcium-dependent glutamate-induced glutamate release.
Autorzy:
Kopach O; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK. Sylantyev S; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.; Rowett Institute, University of Aberdeen, Ashgrove Road West, Aberdeen AB25 2ZD, UK. Bard L; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK. Michaluk P; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.; BRAINCITY, Laboratory of Neurobiology, Nencki Institute of Experimental Biology PAS, 3 Pasteur Street, 02-093 Warsaw, Poland. HellerJP; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.; School of Biotechnology, Dublin City University, Dublin 9, Ireland. Gutierrez Del Arroyo A; Translational Medicine and Therapeutics, Queen Mary University of London, Mile End Road, London E1 4NS, UK. Ackland GL; Translational Medicine and Therapeutics, Queen Mary University of London, Mile End Road, London E1 4NS, UK. Gourine AV; Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK. Rusakov DA; Queen Square Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.
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Źródło:
IScience [iScience] 2023 Jun 28; Vol. 26 (7), pp. 107236. Date of Electronic Publication: 2023 Jun 28 (Print Publication: 2023).
Super-resolution imaging to reveal the nanostructure of tripartite synapses.
Autorzy:
Aleksejenko N; School of Biotechnology and National Institute for Cellular Biotechnology (NICB), Dublin City University, Glasnevin, Ireland. HellerJP; School of Biotechnology and National Institute for Cellular Biotechnology (NICB), Dublin City University, Glasnevin, Ireland.; Queen Square Institute of Neurology, University College London, London, United Kingdom.
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Źródło:
Neuronal signaling [Neuronal Signal] 2021 Oct 14; Vol. 5 (4), pp. NS20210003. Date of Electronic Publication: 2021 Oct 14 (Print Publication: 2021).
Rapid recycling of glutamate transporters on the astroglial surface.
Autorzy:
Michaluk P; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.; BRAINCITY, Laboratory of Neurobiology, Nencki Institute of Experimental Biology PAS, Warsaw, Poland. HellerJP; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.; School of Biotechnology and National Institute for Cellular Biotechnology (NICB), Dublin City University, Glasnevin, Ireland. Rusakov DA; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
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ELife [Elife] 2021 Apr 16; Vol. 10. Date of Electronic Publication: 2021 Apr 16.
Antagomir-mediated suppression of microRNA-134 reduces kainic acid-induced seizures in immature mice.
Autorzy:
Campbell A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland.; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland. Morris G; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland.; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland. HellerJP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland.; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland.; Queen Square Institute of Neurology, University College London, London, UK. Langa E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland.; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland. Brindley E; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland. Worm J; Roche Innovation Center Copenhagen, Copenhagen, Denmark. Jensen MA; Roche Innovation Center Copenhagen, Copenhagen, Denmark. Miller MT; F. Hoffmann-La Roche Ltd, Basel, Switzerland. Henshall DC; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland. .; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland. .; INFANT Research Centre, University College Cork, Cork, Ireland. . Reschke CR; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin, D02 YN77, Ireland.; FutureNeuro, The SFI Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, Dublin, Ireland.
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 11; Vol. 11 (1), pp. 340. Date of Electronic Publication: 2021 Jan 11.
LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.
Autorzy:
Henneberger C; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), 53175 Bonn, Germany. Electronic address: . Bard L; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Panatier A; INSERM U1215, Neurocentre Magendie, 33000 Bordeaux, France; Université de Bordeaux, 33000 Bordeaux, France; Interdisciplinary Institute for Neuroscience, CNRS UMR 5297, 33000 Bordeaux, France. Reynolds JP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Kopach O; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Medvedev NI; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK. Minge D; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany. Herde MK; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany. Anders S; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, 53127 Bonn, Germany. Kraev I; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK. HellerJP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Rama S; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Zheng K; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Jensen TP; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Sanchez-Romero I; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria. Jackson CJ; Research School of Chemistry, Australian National University, Acton, ACT 2601, Australia. Janovjak H; Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria; EMBL Australia, Australian Regenerative Medicine Institute, Faculty of Medicine, Nursing and Health Science, Monash University, Melbourne, VIC 3800, Australia. Ottersen OP; Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway; Karolinska Institutet, 171 77 Stockholm, Sweden. Nagelhus EA; Institute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway. Oliet SHR; INSERM U1215, Neurocentre Magendie, 33000 Bordeaux, France; Université de Bordeaux, 33000 Bordeaux, France. Stewart MG; Life Sciences, The Open University, Milton Keynes MK7 6AA, UK. Electronic address: . Nägerl UV; Université de Bordeaux, 33000 Bordeaux, France; Interdisciplinary Institute for Neuroscience, CNRS UMR 5297, 33000 Bordeaux, France. Electronic address: . Rusakov DA; UCL Queen Square Institute of Neurology, University College London, London WC1N 3BG, UK. Electronic address: .
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Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 919-936.e11. Date of Electronic Publication: 2020 Sep 24.
Imaging tripartite synapses using super-resolution microscopy.
Autorzy:
HellerJP; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland. Electronic address: j.heller@ucl.ac.uk. Odii T; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom; Department of Physiology, Faculty of Basic Medical Sciences, Alex Ekwueme Federal University Ndufu-Alike Ikwo, PMB 1010 Abakaliki, Nigeria. Zheng K; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom. Rusakov DA; UCL Queen Square Institute of Neurology, University College London, London, United Kingdom. Electronic address: .
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Źródło:
Methods (San Diego, Calif.) [Methods] 2020 Mar 01; Vol. 174, pp. 81-90. Date of Electronic Publication: 2019 May 31.
Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons.
Autorzy:
Haq N; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom. Schmidt-Hieber C; Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom. Sialana FJ; Department of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria. Ciani L; Department of Cell and Developmental Biology, University College London, London, United Kingdom. HellerJP; Institute of Neurology, University College London, London, United Kingdom. Stewart M; MRC Harwell Institute, Mary Lyon Centre, Harwell Campus, Oxfordshire, United Kingdom. Bentley L; MRC Harwell Institute, Mary Lyon Centre, Harwell Campus, Oxfordshire, United Kingdom. Wells S; MRC Harwell Institute, Mary Lyon Centre, Harwell Campus, Oxfordshire, United Kingdom. Rodenburg RJ; Radboud Center for Mitochondrial Medicine, Translational Metabolic Laboratory, Department of Pediatrics, Radboud University Medical Centre, Nijmegen, the Netherlands. Nolan PM; MRC Harwell Institute, Mary Lyon Centre, Harwell Campus, Oxfordshire, United Kingdom. Forsythe E; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom. Wu MC; Neurodigitech, LLC, San Diego, California, United States of America. Lubec G; Programme in Proteomics, Paracelsus Private Medical University, Salzburg, Austria. Salinas P; Department of Cell and Developmental Biology, University College London, London, United Kingdom. Häusser M; Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, London, United Kingdom. Beales PL; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom. Christou-Savina S; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
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Źródło:
PLoS biology [PLoS Biol] 2019 Sep 03; Vol. 17 (9), pp. e3000414. Date of Electronic Publication: 2019 Sep 03 (Print Publication: 2019).
The Nanoworld of the Tripartite Synapse: Insights from Super-Resolution Microscopy.
Autorzy:
HellerJP; UCL Institute of Neurology, University College London, London, United Kingdom. Rusakov DA; UCL Institute of Neurology, University College London, London, United Kingdom.; Institute of Neuroscience, University of Nizhny Novgorod, Nizhny Novgorod, Russia.
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Frontiers in cellular neuroscience [Front Cell Neurosci] 2017 Nov 24; Vol. 11, pp. 374. Date of Electronic Publication: 2017 Nov 24 (Print Publication: 2017).
Probing nano-organization of astroglia with multi-color super-resolution microscopy.
Autorzy:
HellerJP; UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, Queen Square House, London WC1N 3BG, United Kingdom. Michaluk P; UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, Queen Square House, London WC1N 3BG, United Kingdom. Sugao K; UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, Queen Square House, London WC1N 3BG, United Kingdom.; Molecular Pathophysiology Research, Drug Research Division, Sumitomo Dainippon Pharma Co., Ltd., Tokyo, 104-8356, Japan. Rusakov DA; UCL Institute of Neurology, Department of Clinical and Experimental Epilepsy, Queen Square House, London WC1N 3BG, United Kingdom.
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Journal of neuroscience research [J Neurosci Res] 2017 Nov; Vol. 95 (11), pp. 2159-2171. Date of Electronic Publication: 2017 Feb 02.
Retinal ganglion cell neuroprotection by an angiotensin II blocker in an ex vivo retinal explant model.
Autorzy:
White AJ; Centre for Vision Research, Westmead Millennium Institute, University of Sydney, Australia Cambridge NIHR Biomedical Research Centre, UK . HellerJP; John van Geest Centre for Brain Repair, University of Cambridge, UK. Leung J; School of Medical Sciences, Discipline of Physiology, University of Sydney, Australia. Tassoni A; John van Geest Centre for Brain Repair, University of Cambridge, UK. Martin KR; John van Geest Centre for Brain Repair, University of Cambridge, UK Cambridge NIHR Biomedical Research Centre, UK Wellcome Trust - MRC Cambridge Stem Cell Institute, University of Cambridge, UK.
Morphological plasticity of astroglia: Understanding synaptic microenvironment.
Autorzy:
HellerJP; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, London, United Kingdom. Rusakov DA; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, Queen Square, London, United Kingdom.
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Źródło:
Glia [Glia] 2015 Dec; Vol. 63 (12), pp. 2133-51. Date of Electronic Publication: 2015 Mar 18.
A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases.
Autorzy:
HellerJP; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge Cambridge, UK ; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London London, UK. Kwok JC; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge Cambridge, UK. Vecino E; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge Cambridge, UK ; Department of Cellular Biology, University of the Basque Country Leioa, UPV/EHU, Bizkaia, Spain. Martin KR; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge Cambridge, UK ; Department of Ophthalmology, NIHR Biomedical Research Centre and Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge Cambridge, UK. Fawcett JW; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge Cambridge, UK.
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Źródło:
Frontiers in cellular neuroscience [Front Cell Neurosci] 2015 Nov 20; Vol. 9, pp. 449. Date of Electronic Publication: 2015 Nov 20 (Print Publication: 2015).
Full length talin stimulates integrin activation and axon regeneration.
Autorzy:
Tan CL; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Kwok JC; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. HellerJP; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Zhao R; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Eva R; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Fawcett JW; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Electronic address: .
Influence of extracellular matrix components on the expression of integrins and regeneration of adult retinal ganglion cells.
Autorzy:
Vecino E; Dept. of Cell Biology and Histology, University of the Basque Country, UPV/EHU, Leioa, Vizcaya, Spain; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom. HellerJP; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom. Veiga-Crespo P; Dept. of Cell Biology and Histology, University of the Basque Country, UPV/EHU, Leioa, Vizcaya, Spain. Martin KR; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom; Welcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom. Fawcett JW; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
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Źródło:
PloS one [PLoS One] 2015 May 27; Vol. 10 (5), pp. e0125250. Date of Electronic Publication: 2015 May 27 (Print Publication: 2015).
Kinesin KIF4A transports integrin β1 in developing axons of cortical neurons.
Autorzy:
Heintz TG; John van Geest Centre for Brain Repair, Dept. Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. HellerJP; John van Geest Centre for Brain Repair, Dept. Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Zhao R; John van Geest Centre for Brain Repair, Dept. Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Caceres A; Laboratorio de Neurobiología Celular y Molecular, Instituto Investigación Médica Mercedes y Martín Ferreyra (INIMEC-CONICET), Friuli 2434, 5016 Córdoba, Argentina. Eva R; John van Geest Centre for Brain Repair, Dept. Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Electronic address: . Fawcett JW; John van Geest Centre for Brain Repair, Dept. Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK. Electronic address: .
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