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Wyszukujesz frazę ""Hemoglobin"" wg kryterium: Temat


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Tytuł :
Compound heterozygosity for hemoglobin S and hemoglobin E in a family of Proto-Australoid origin: a case report.
Autorzy :
Basumatary N; Department of Biotechnology, Bodoland University, Kokrajhar, Assam, India.
Baruah D; Department of Pathology, Fakhruddin Ali Ahmed Medical College and Hospital, Barpeta, Assam, India.
Sarma PK; Department of Medicine, Fakhruddin Ali Ahmed Medical College and Hospital, Barpeta, Assam, India.
Sarmah J; Department of Biotechnology and Co-ordinator, DBT (Govt. of India) sponsored Bioinformatics Infrastructure Facility, Bodoland University, Kokrajhar, Assam, India. .
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 Aug 02; Vol. 15 (1), pp. 386. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Hemoglobin E*/genetics
Hemoglobinopathies*/diagnosis
Hemoglobinopathies*/genetics
Sickle Cell Trait*
Adolescent ; Hemoglobin, Sickle ; Humans ; India ; Male
Czasopismo naukowe
Tytuł :
Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC).
Autorzy :
Brewin JN; Kings College London, UK; Kings College Hospital, London. .
Rooks H; Kings College London.
Gardner K; Kings College London, UK; Guys and St Thomas Hospital, London.
Senior H; Kings College London.
Morje M; Kings College London.
Patel H; Kings College London.
Calvet D; Henri Mondor Hopital, Paris.
Bartolucci P; Henri Mondor Hopital, Paris.
Thein SL; NIH, Bethesda.
Menzel S; Kings College London.
Rees DC; Kings College London, UK; Kings College Hospital, London.
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Źródło :
Haematologica [Haematologica] 2021 Jun 01; Vol. 106 (6), pp. 1770-1773. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Letter
MeSH Terms :
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/genetics
Hemoglobin SC Disease*
Cerebral Infarction/genetics ; Genome-Wide Association Study ; Hemoglobin, Sickle/genetics ; Humans
Opinia redakcyjna
Tytuł :
A roadmap for the standardization of hemoglobin A 2 .
Autorzy :
Mosca A; Dip. di Fisiopatologia Medico-Chirurgica e dei Trapianti and Centro per la Riferibilità Metrologica in Medicina di Laboratorio (CIRME), Università degli Studi di Milano, Milano, Italy; Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), Milano, Italy. Electronic address: .
Paleari R; Dip. di Fisiopatologia Medico-Chirurgica e dei Trapianti and Centro per la Riferibilità Metrologica in Medicina di Laboratorio (CIRME), Università degli Studi di Milano, Milano, Italy; Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche (ITB-CNR), Milano, Italy.
Harteveld CL; Dept. of Clinical Genetics/LDGA, Leiden University Medical Center, Leiden, the Netherlands.
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Corporate Authors :
IFCC ICSH Joint Working Group for standardization of HbA2
Źródło :
Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2021 Jan; Vol. 512, pp. 185-190. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Hemoglobin A2*/analysis
Calibration ; Chromatography, High Pressure Liquid ; Glycated Hemoglobin A/analysis ; Hemoglobin, Sickle ; Humans ; Reference Standards
Czasopismo naukowe
Tytuł :
Glycated Hemoglobin A 1c , Lung Function, and Hospitalizations Among Adults with Asthma.
Autorzy :
Yang G; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa; Department of Neonatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Han YY; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Forno E; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Yan Q; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Rosser F; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Chen W; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa.
Celedón JC; Division of Pediatric Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pa. Electronic address: .
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Źródło :
The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2020 Nov - Dec; Vol. 8 (10), pp. 3409-3415.e1. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma*/diagnosis
Asthma*/epidemiology
Hemoglobin A*
Adult ; Aged ; Cross-Sectional Studies ; Glycated Hemoglobin A/analysis ; Hospitalization ; Humans ; Lung ; Middle Aged ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
MicroRNA expression patterns in HbE/β-thalassemia patients: The passwords to unlock fetal hemoglobin expression in β-hemoglobinopathies.
Autorzy :
Das SS; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India.
Das S; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India.
Byram PK; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India.
Rahaman M; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India.
Dolai TK; Haematology Department, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal 700014, India.
Chatterjee A; Department of Pediatric Medicine, Rampurhat Government Medical College and Hospital, Rampurhat, Birbhum, West Bengal 731224, India.
Chakravorty N; School of Medical Science and Technology, Indian Institute of Technology Kharagpur, West Bengal 721302, India. Electronic address: .
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Źródło :
Blood cells, molecules & diseases [Blood Cells Mol Dis] 2021 Mar; Vol. 87, pp. 102523. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hemoglobin E/*genetics
MicroRNAs/*genetics
beta-Thalassemia/*genetics
Cells, Cultured ; Down-Regulation ; Fetal Hemoglobin/genetics ; Gene Expression Profiling ; Gene Regulatory Networks ; Humans ; Transcriptome ; Up-Regulation
Czasopismo naukowe
Tytuł :
A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression.
Autorzy :
Badat M; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Davies JOJ; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Fisher CA; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Downes DJ; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Rose A; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Glenthøj AB; Department of Hematology, Herlev and Gentofte Hospital, Copenhagen, Denmark.
van Beers EJ; Van Creveldkliniek, Division of Internal Medicine and Dermatology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands; and.
Harteveld CL; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.
Higgs DR; Medical Research Council Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
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Źródło :
Blood [Blood] 2021 Jan 28; Vol. 137 (4), pp. 572-575.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Enhancer Elements, Genetic*
Hemoglobin H/*genetics
alpha-Globins/*genetics
alpha-Thalassemia/*genetics
Adult ; Alleles ; Chromatin/genetics ; Chromatin/ultrastructure ; Chromosomes, Human, Pair 16/genetics ; Chromosomes, Human, Pair 16/ultrastructure ; Erythroblasts/pathology ; Erythropoiesis ; Female ; Gene Deletion ; Gene Expression Regulation ; Genotype ; Hemoglobin E/genetics ; Hemoglobin H/analysis ; Humans ; Male ; Pedigree ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Sequence Deletion ; Suriname/ethnology ; alpha-Globins/biosynthesis ; alpha-Thalassemia/blood ; beta-Globins/genetics
Czasopismo naukowe
Tytuł :
Endothelial TLR4 Expression Mediates Vaso-Occlusive Crisis in Sickle Cell Disease.
Autorzy :
Beckman JD; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Abdullah F; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Chen C; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Kirchner R; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Rivera-Rodriguez D; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Kiser ZM; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Nguyen A; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Zhang P; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Nguyen J; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Hebbel RP; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Belcher JD; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
Vercellotti GM; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jan 19; Vol. 11, pp. 613278. Date of Electronic Publication: 2021 Jan 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Anemia, Sickle Cell/*metabolism
Endothelium/*metabolism
Hemoglobin A/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; Erythrocytes/metabolism ; Female ; Hematopoiesis/physiology ; Heme/metabolism ; Hemoglobin, Sickle/metabolism ; Humans ; Inflammation/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Microvessels ; NF-kappa B/metabolism ; Signal Transduction/physiology ; Transcription Factor RelA/metabolism
Czasopismo naukowe
Tytuł :
Production of functional human fetal hemoglobin in Nicotiana benthamiana for development of hemoglobin-based oxygen carriers.
Autorzy :
Kanagarajan S; Department of Plant Breeding, Swedish University of Agricultural Sciences, Lomma, Sweden.
Carlsson MLR; Department of Plant Breeding, Swedish University of Agricultural Sciences, Lomma, Sweden.
Chakane S; Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Lund, Sweden.
Kettisen K; Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Lund, Sweden.
Smeds E; Division of Infection Medicine, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.
Kumar R; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Ortenlöf N; Division of Infection Medicine, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.
Gram M; Pediatrics, Department of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Åkerström B; Division of Infection Medicine, Department of Clinical Sciences in Lund, Lund University, Lund, Sweden.
Bülow L; Division of Pure and Applied Biochemistry, Department of Chemistry, Lund University, Lund, Sweden.
Zhu LH; Department of Plant Breeding, Swedish University of Agricultural Sciences, Lomma, Sweden. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 01; Vol. 184, pp. 955-966. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Fetal Hemoglobin/*genetics
Oxygen/*metabolism
Tobacco/*genetics
Fetal Hemoglobin/isolation & purification ; Fetal Hemoglobin/metabolism ; Humans ; Hydrogen Bonding ; Plant Proteins/isolation & purification ; Plants, Genetically Modified/growth & development ; Plants, Genetically Modified/metabolism ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Tobacco/growth & development ; Tobacco/metabolism
Czasopismo naukowe
Tytuł :
Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening.
Autorzy :
Anderson JJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK .
Welsh P; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Ho FK; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Ferguson LD; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Welsh CE; Population and Health Sciences, Newcastle University, Newcastle upon Tyne, UK.
Pellicori P; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Cleland JGF; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Forbes J; Faculty of Education and Health Sciences, University of Limerick, Limerick, Ireland.
Iliodromiti S; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.; Centre of Women's Health, Yvonne Carter Building, Queen Mary University of London, London, UK.
Boyle J; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Lindsay R; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Celis-Morales C; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Gray SR; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Katikireddi SV; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Gill JMR; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Pell JP; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Sattar N; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK .
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Źródło :
BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2021 Aug; Vol. 9 (1).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Specimen Banks*
Diabetes Mellitus*/diagnosis
Diabetes Mellitus*/ethnology
Ethnic Groups*
Glycated Hemoglobin A*/analysis
Prediabetic State*/diagnosis
Prediabetic State*/ethnology
Adult ; Aged ; Cross-Sectional Studies ; Humans ; Middle Aged ; Prevalence ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
Improved individual and population-level HbA1c estimation using CGM data and patient characteristics.
Autorzy :
Grossman J; Department of Management Science and Engineering, Stanford School of Engineering, Stanford, CA, USA.
Ward A; Department of Management Science and Engineering, Stanford School of Engineering, Stanford, CA, USA.
Crandell JL; School of Nursing, Department of Biostatistics, UNC Chapel Hill, Chapel Hill, NC, USA.
Prahalad P; Division of Pediatric Endocrinology, Stanford School of Medicine, Stanford, CA, USA; Lucile Packard Children's Hospital, Stanford, CA, USA.
Maahs DM; Division of Pediatric Endocrinology, Stanford School of Medicine, Stanford, CA, USA; Lucile Packard Children's Hospital, Stanford, CA, USA; Stanford Diabetes Research Center, Stanford School of Medicine, Stanford, CA, USA; Department of Health Research and Policy, Stanford School of Medicine, Stanford, CA, USA.
Scheinker D; Department of Management Science and Engineering, Stanford School of Engineering, Stanford, CA, USA; Division of Pediatric Endocrinology, Stanford School of Medicine, Stanford, CA, USA; Lucile Packard Children's Hospital, Stanford, CA, USA; Stanford Diabetes Research Center, Stanford School of Medicine, Stanford, CA, USA; Clinical Excellence Research Center, Stanford School of Medicine, Stanford, CA, USA. Electronic address: .
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Źródło :
Journal of diabetes and its complications [J Diabetes Complications] 2021 Aug; Vol. 35 (8), pp. 107950. Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blood Specimen Collection/*statistics & numerical data
COVID-19/*epidemiology
Diabetes Mellitus, Type 1/*blood
Diabetes Mellitus, Type 1/*epidemiology
Glycated Hemoglobin A/*analysis
Adolescent ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Blood Glucose Self-Monitoring/instrumentation ; Blood Glucose Self-Monitoring/methods ; Blood Specimen Collection/methods ; Blood Specimen Collection/standards ; Child ; Cohort Studies ; Female ; Glycated Hemoglobin A/metabolism ; Health Services Accessibility/statistics & numerical data ; Humans ; Machine Learning/standards ; Male ; Pandemics ; Remote Sensing Technology/methods ; Remote Sensing Technology/standards ; SARS-CoV-2/physiology ; Statistics as Topic/instrumentation ; Statistics as Topic/methods ; Young Adult
Czasopismo naukowe
Tytuł :
A polygenic score for acute vaso-occlusive pain in pediatric sickle cell disease.
Autorzy :
Rampersaud E; Department of Computational Biology.
Kang G; Department of Biostatistics.
Palmer LE; Department of Computational Biology.; Department of Hematology.
Rashkin SR; Department of Hematology.; Center for Applied Bioinformatics.
Wang S; Department of Computational Biology.
Bi W; Department of Biostatistics.
Alberts NM; Department of Psychology, Concordia University, Montreal, Canada.
Anghelescu D; Department of Anesthesiology, St. Jude Children's Research Hospital, Memphis, TN.
Barton M; Department of Hematology.
Birch K; Department of Computational Biology.
Boulos N; Department of Hematology.
Brandow AM; Section of Hematology/Oncology/Bone Marrow Transplantation, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Brooke RJ; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN.
Chang TC; Department of Computational Biology.
Chen W; Department of Computational Biology.
Cheng Y; Department of Hematology.
Ding J; Department of Biostatistics.
Easton J; Department of Computational Biology.
Hodges JR; Department of Hematology.
Kanne CK; School of Public Health, The University of Texas Health Science Center-Houston (UTHealth), Houston, TX.
Levy S; HudsonAlpha Institute for Biotechnology, Huntsville, AL.
Mulder H; Department of Computational Biology.
Patel AP; School of Public Health, The University of Texas Health Science Center-Houston (UTHealth), Houston, TX.
Puri L; Department of Hematology.
Rosencrance C; Department of Computational Biology.
Rusch M; Department of Computational Biology.
Sapkota Y; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN.
Sioson E; Department of Computational Biology.
Sharma A; Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN.
Tang X; Department of Hematology.
Thrasher A; Department of Computational Biology.
Wang W; Department of Hematology.
Yao Y; Department of Hematology.
Yasui Y; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN.
Yergeau D; Department of Computational Biology.
Hankins JS; Department of Hematology.
Sheehan VA; Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA.
Downing JR; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN; and.
Estepp JH; Department of Hematology.
Zhang J; Department of Computational Biology.
DeBaun M; Vanderbilt University Children's Hospital, Nashville, TN.
Wu G; Department of Computational Biology.
Weiss MJ; Department of Hematology.
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Źródło :
Blood advances [Blood Adv] 2021 Jul 27; Vol. 5 (14), pp. 2839-2851.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/genetics
Fetal Hemoglobin*/genetics
Child ; Humans ; Longitudinal Studies ; Pain ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
Autorzy :
Gilmartin AG; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Groy A; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Gore ER; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Atkins C; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Long ER; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Montoute MN; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Wu Z; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Halsey W; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
McNulty DE; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Ennulat D; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Rueda L; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Pappalardi M; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Kruger RG; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
McCabe MT; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Raoof A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, UK.
Butlin R; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, UK.
Stowell A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, UK.
Cockerill M; Drug Discovery Unit, Cancer Research UK Manchester Institute, Univ of Manchester and MediTech Media,UK.
Waddell I; Cancer Research UK Manchester Institute, Univ of Manchester and Charles River Laboratories, Essex, UK.
Ogilvie D; Cancer Research UK Manchester Institute, Univ of Manchester and Framingham Consulting Limited, UK.
Luengo J; GlaxoSmithKline, Collegeville, PA and Prelude Therapeutics, Newark, DE, USA.
Jordan A; Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, UK.
Benowitz AB; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
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Źródło :
Haematologica [Haematologica] 2021 Jul 01; Vol. 106 (7), pp. 1979-1987. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/genetics
Fetal Hemoglobin*/genetics
Animals ; Azacitidine/pharmacology ; DNA Methylation ; Mice ; gamma-Globins/genetics
Czasopismo naukowe
Tytuł :
Improved Detection of Abnormal Glucose Tolerance in Africans: The Value of Combining Hemoglobin A 1c With Glycated Albumin.
Autorzy :
Hobabagabo AF; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.; National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD.
Osei-Tutu NH; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Hormenu T; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Shoup EM; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
DuBose CW; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Mabundo LS; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Ha J; Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Sherman A; Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Chung ST; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Sacks DB; National Institutes of Health Clinical Center, Bethesda, MD.
Sumner AE; Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD .; National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD.
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Źródło :
Diabetes care [Diabetes Care] 2020 Oct; Vol. 43 (10), pp. 2607-2613. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
African Continental Ancestry Group/*ethnology
Glucose Intolerance/*diagnosis
Glucose Intolerance/*ethnology
Glycated Hemoglobin A/*analysis
Serum Albumin/*analysis
Adult ; Africa/ethnology ; Aged ; Biomarkers/analysis ; Biomarkers/blood ; Blood Glucose/analysis ; Female ; Fructosamine/analysis ; Fructosamine/blood ; Glucose Intolerance/epidemiology ; Glucose Tolerance Test/methods ; Glucose Tolerance Test/standards ; Hemoglobin, Sickle/analysis ; Humans ; Male ; Middle Aged ; Obesity/blood ; Obesity/complications ; Obesity/diagnosis ; Obesity/ethnology ; Predictive Value of Tests ; Quality Improvement ; Reproducibility of Results ; United States/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Bulk volume susceptibility difference between deoxyhemoglobin and oxyhemoglobin for HbA and HbS: A comparative study.
Autorzy :
Eldeniz C; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Binkley MM; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
Fields M; Department of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, USA.
Guilliams K; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, USA.
Ragan DK; Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Chen Y; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
Lee JM; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.
Ford AL; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.
An H; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Neurology, Washington University in St. Louis, St. Louis, Missouri, USA.; Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.
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Źródło :
Magnetic resonance in medicine [Magn Reson Med] 2021 Jun; Vol. 85 (6), pp. 3383-3393. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hemoglobin A*
Hemoglobin, Sickle*
Hemoglobins ; Humans ; Oxygen ; Oxyhemoglobins
Czasopismo naukowe
Tytuł :
Genotypic Diversity among Angolan Children with Sickle Cell Anemia.
Autorzy :
Delgadinho M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Ginete C; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Santos B; Centro de Investigação em Saúde de Angola (CISA), Caxito, Angola.; Hospital Pediátrico David Bernardino (HPDB), Luanda 3067, Angola.
Miranda A; Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA), 1649-016 Lisbon, Portugal.
Brito M; H&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.; Centro de Investigação em Saúde de Angola (CISA), Caxito, Angola.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 May 19; Vol. 18 (10). Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anemia, Sickle Cell*/epidemiology
Anemia, Sickle Cell*/genetics
Fetal Hemoglobin*/analysis
Fetal Hemoglobin*/genetics
Child ; Genotype ; Haplotypes ; Humans ; Infant, Newborn ; Polymorphism, Single Nucleotide ; Repressor Proteins/genetics
Czasopismo naukowe
Tytuł :
Anesthetic Considerations for Percutaneous and Open Right Atrial Thrombectomy in a Hemoglobin SC Patient.
Autorzy :
Chen T; Department of Anesthesiology, Warren Alpert Medical School of Brown University, Providence, RI. Electronic address: .
Mordehai E; Department of Anesthesiology, Warren Alpert Medical School of Brown University, Providence, RI.
Sodha N; Department of Surgery, Warren Alpert Medical School of Brown University, Providence, RI.
Kolodziejczak M; Division of Cardiothoracic Surgery, Rhode Island Hospital, Providence, RI.
Savio C; Division of Cardiothoracic Surgery, Rhode Island Hospital, Providence, RI.
Maslow A; Department of Anesthesiology, Warren Alpert Medical School of Brown University, Providence, RI.
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Źródło :
Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2021 Apr; Vol. 35 (4), pp. 1161-1166. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Case Reports
MeSH Terms :
Anesthetics*
Hemoglobin SC Disease*
Hemoglobinopathies*
Thrombectomy*
Hemoglobins ; Humans
Raport
Tytuł :
Prediabetes and pregnancy: Early pregnancy HbA 1c identifies Australian Aboriginal women with high-risk of gestational diabetes mellitus and adverse perinatal outcomes.
Autorzy :
Jamieson EL; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, Building 3 Edith Cowan University, Robertson Drive, PO Box 412, Bunbury, WA 6230, Australia.
Spry EP; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 12 Napier Terrace, PO Box 1377, Broome, WA 6725, Australia; Kimberley Aboriginal Medical Services, 12 Napier Terrace, Broome, WA 6725, Australia.
Kirke AB; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, Building 3 Edith Cowan University, Robertson Drive, PO Box 412, Bunbury, WA 6230, Australia.
Griffiths E; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 12 Napier Terrace, PO Box 1377, Broome, WA 6725, Australia.
Porter C; Geraldton Regional Aboriginal Medical Service, Rifle Range Road, Rangeway, WA 6530, Australia.
Roxburgh C; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 31 Stirling Terrace, Albany, WA 6330, Australia.
Singleton S; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 12 Napier Terrace, PO Box 1377, Broome, WA 6725, Australia.
Sterry K; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, St Alban's Road (rear Kalgoorlie Hospital), Kalgoorlie, WA 6433, Australia.
Atkinson DN; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 12 Napier Terrace, PO Box 1377, Broome, WA 6725, Australia.
Marley JV; The University of Western Australia, Medical School, The Rural Clinical School of Western Australia, 12 Napier Terrace, PO Box 1377, Broome, WA 6725, Australia; Kimberley Aboriginal Medical Services, 12 Napier Terrace, Broome, WA 6725, Australia. Electronic address: .
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Źródło :
Diabetes research and clinical practice [Diabetes Res Clin Pract] 2021 Jun; Vol. 176, pp. 108868. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Oceanic Ancestry Group*/ethnology
Pregnancy Outcome*/ethnology
Diabetes, Gestational/*diagnosis
Glycated Hemoglobin A/*analysis
Prediabetic State/*diagnosis
Adolescent ; Adult ; Australia/ethnology ; Cohort Studies ; Diabetes, Gestational/blood ; Diabetes, Gestational/ethnology ; Diabetes, Gestational/etiology ; Female ; Gestational Age ; Glucose Tolerance Test ; Glycated Hemoglobin A/metabolism ; Humans ; Infant, Newborn ; Male ; Prediabetic State/blood ; Prediabetic State/complications ; Prediabetic State/ethnology ; Pregnancy ; Pregnancy Complications/blood ; Pregnancy Complications/diagnosis ; Pregnancy Complications/ethnology ; Pregnancy Trimester, First/blood ; Prognosis ; Prospective Studies ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Another 'BEE'? - Brain-Eye-Ear (BEE) Disease Secondary to HbSC Disease Masquerading as Multiple Sclerosis.
Autorzy :
Wallach AI; Former Affiliation/Place Clinical Care was provided: NYU MS Comprehensive Care Center, Department of Neurology, NYU Langone Health, New York, USA; Current Affiliation/ Place Manuscript was written: Alfiero and Lucia Palestroni MS Comprehensive Care Center, Holy Name Medical Center, New Jersey, USA. Electronic address: .
Borja MJ; Division of Neuroradiology, Department of Radiology, NYU Langone Health, New York, USA.
Chen D; Division of Neuroradiology, Department of Radiology, NYU Langone Health, New York, USA.
Eisenberg R; Allergy & Immunology, Department of Pediatrics, Children's Hospital at Montefiore, New York, USA.
Modi YS; Department of Ophthalmology, NYU Langone Health, New York, USA.
Zhang C; Division of Vascular Neurology, Department of Neurology, NYU Langone Health, New York, USA.
Shepherd TM; Division of Neuroradiology, Department of Radiology, NYU Langone Health, New York, USA.
Nath A; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke and National Institutes of Health, New York, USA.
Smith B; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke and National Institutes of Health, New York, USA.
Scher JU; Division of Rheumatology, Department of Medicine, NYU Langone Health, New York, USA.
Cho C; Division of Otoneurology, Departments of Neurology and Otolaryngology, NYU Langone Health, New York, USA.
Kister I; NYU MS Comprehensive Care Center, Department of Neurology, NYU Langone Health, New York, USA.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Apr; Vol. 30 (4), pp. 105618. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Case Reports
MeSH Terms :
Whole Exome Sequencing*
Hearing Loss, Unilateral/*etiology
Hemoglobin SC Disease/*diagnosis
Hemoglobins, Abnormal/*genetics
Leukoencephalopathies/*etiology
Multiple Sclerosis/*diagnosis
Vision Disorders/*etiology
Diagnostic Errors ; Genetic Predisposition to Disease ; Hearing Loss, Unilateral/diagnosis ; Hearing Loss, Unilateral/physiopathology ; Hemoglobin SC Disease/complications ; Hemoglobin SC Disease/genetics ; Humans ; Leukoencephalopathies/diagnostic imaging ; Leukoencephalopathies/physiopathology ; Magnetic Resonance Imaging ; Male ; Multiple Sclerosis/complications ; Multiple Sclerosis/drug therapy ; Phenotype ; Predictive Value of Tests ; Vision Disorders/diagnosis ; Vision Disorders/physiopathology ; Young Adult
Raport
Tytuł :
Validation of the Siggaard-Andersen Acid-Base Nomogram for Hemoglobin F: Implications for Fetal Cord Blood Gas Analysis.
Autorzy :
Whitham M; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Pagaduan J; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Clark SL; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Singh I; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Belfort M; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Devaraj S; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Cao J; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Shetty A; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Pai S; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
Fox K; Department of Obstetrics and Gynecology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
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Źródło :
American journal of perinatology [Am J Perinatol] 2019 Dec; Vol. 36 (14), pp. 1481-1484. Date of Electronic Publication: 2019 Jan 23.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Blood Gas Analysis*
Fetal Hemoglobin*
Nomograms*
Bicarbonates/*blood
Fetal Blood/*chemistry
Acid-Base Equilibrium ; Acid-Base Imbalance ; Adult ; Female ; Hemoglobin A ; Humans ; Hydrogen-Ion Concentration ; Pregnancy ; Prospective Studies
Czasopismo naukowe

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