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Tytuł:
Novel Insights into the Pathophysiology and Treatment of Sickle Cell Disease.
Autorzy:
Araújo ADS; Department of Hematology, Fundação de Hematologia e Hemoterapia de Pernambucol, Brazi.
Silva Pinto AC; Department of Medical Imaging, Hematology and Oncology, Hemocentro de Ribeirão Preto, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP, Brazil.
Lobo CLC; Department of Clinical Research, Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti (HEMORIO), Brazil.
Figueiredo MS; Department of Clinical and Experimental Oncology, Escola Paulista de Medicina da Universidade Federal de São Paulo (UNIFESP), Brazil.
Menosi Gualandro SF; Department of Hematology, Hospital das Clínicas da Faculdade de Medicina da USP, Brazi.
Olalla Saad ST; Department of Internal Medicine, Faculdade de Ciências Médicas - UNICAMP, Brazil.
Cancado RD; Department of Hematology and Oncology, Faculdade de Ciências Médicas da Santa Casa de São Paulo, Brazil.
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Źródło:
Hemoglobin [Hemoglobin] 2023 Nov; Vol. 47 (2), pp. 71-79. Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hemoglobin, Sickle*
Anemia, Sickle Cell*/drug therapy
Humans ; Erythrocytes ; Hemoglobins ; Erythrocytes, Abnormal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
On the feasibility of malaria hypothesis.
Autorzy:
Habibzadeh F; Global Virus Network (GVN), Middle East Region, Shiraz, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 09; Vol. 14 (1), pp. 5800. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Malaria*/genetics
Anemia, Sickle Cell*/genetics
Child ; Female ; Humans ; Feasibility Studies ; Hemoglobin, Sickle/genetics ; Gene Frequency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Bone Health Impairment in Patients with Hemoglobinopathies: From Biological Bases to New Possible Therapeutic Strategies.
Autorzy:
Di Paola A; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Marrapodi MM; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Di Martino M; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Giliberti G; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Di Feo G; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Rana D; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Ahmed S; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Argenziano M; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Rossi F; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
Roberti D; Department of Woman, Child and General and Specialist Surgery, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Hemoglobinopathies*/genetics
Anemia, Sickle Cell*/genetics
Thalassemia*
beta-Thalassemia*/genetics
Humans ; Bone Density ; Hemoglobin, Sickle
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Sickle-Cell Fiber Revisited.
Autorzy:
Bishop MF; Department of Physics, Virginia Commonwealth University, Richmond, VA 23284, USA.
Ferrone FA; Department of Physics, Drexel University, Philadelphia, PA 19104, USA.
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Źródło:
Biomolecules [Biomolecules] 2023 Feb 22; Vol. 13 (3). Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Hemoglobin, Sickle*/genetics
Anemia, Sickle Cell*/genetics
Humans ; Hemoglobins/genetics ; Polymers ; Point Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease.
Autorzy:
Kuczynski CE; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 27101, USA.
Porada CD; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 27101, USA.
Atala A; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 27101, USA.
Cho SS; Department of Physics, Wake Forest University, Winston-Salem, NC, 27109, USA. .; Department of Computer Science, Wake Forest University, Winston-Salem, NC, 27109, USA. .
Almeida-Porada G; Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 27101, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 02; Vol. 14 (1), pp. 276. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Hemoglobins*/genetics
Anemia, Sickle Cell*/therapy
Adult ; Humans ; Animals ; Sheep ; Hemoglobin A ; beta-Globins/genetics ; Models, Animal ; Hemoglobin, Sickle/genetics ; Hemoglobin, Sickle/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Haemoglobin S testing using HEA BeadChip™ technology: Lifeblood comparison with clinical diagnosis.
Autorzy:
Wong P; Clinical Services and Research, Australian Red Cross Lifeblood, Kelvin Grove, Australia.; School of Medicine, University of Queensland, St Lucia, Australia.; Department of Cancer Care Services, Toowoomba Hospital, Toowoomba, Queensland, Australia.
Baidya S; Clinical Services and Research, Australian Red Cross Lifeblood, Kelvin Grove, Australia.
Daly J; Clinical Services and Research, Australian Red Cross Lifeblood, Kelvin Grove, Australia.
Powley T; Clinical Services and Research, Australian Red Cross Lifeblood, Kelvin Grove, Australia.
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Źródło:
Vox sanguinis [Vox Sang] 2022 Aug; Vol. 117 (8), pp. 1001-1005. Date of Electronic Publication: 2022 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell*
Hemoglobin, Sickle*/analysis
Hemoglobin, Sickle*/genetics
Australia ; Hematologic Tests ; Hemoglobins/analysis ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes.
Autorzy:
Gnondjui AA; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.; Laboratoire Biologie et Santé, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
Toure OA; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.
Ako BA; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.
Koui TS; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.; Laboratoire Biologie et Santé, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
Assohoun SE; Laboratoire de Mécanique et Informatique, Université Felix Houphouët BoignyCôte d'Ivoire, Abidjan, Côte d'Ivoire.
Gbessi EA; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.; Laboratoire Biologie et Santé, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
N'Guessan LT; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.
Tuo K; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.
Beourou S; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire.
Assi SB; Institut Pierre Richet/Programme National de Lutte contre le Paludisme, Bouaké, Côte d'Ivoire.
Yapo FA; Laboratoire Biologie et Santé, Université Felix Houphouët Boigny, Abidjan, Côte d'Ivoire.
Sanogo I; Service d'Hématologie, CHU Yopougon, Abidjan, Côte d'Ivoire.
Jambou R; Unité de Paludologie, Institut Pasteur Côte d'Ivoire, 01 BP 490, Abidjan 01, Côte d'Ivoire. .; Global Health Department, Institut Pasteur Paris, 25 rue du Dr Roux, 75015, Paris, France. .
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Źródło:
Malaria journal [Malar J] 2024 Jan 04; Vol. 23 (1), pp. 9. Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Parasites*
Artemisinins*/pharmacology
Artemisinins*/therapeutic use
Malaria, Falciparum*/parasitology
Anemia, Sickle Cell*
Humans ; Animals ; Plasmodium falciparum/genetics ; Cote d'Ivoire ; Hemoglobin, Sickle
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Newborn screening for sickle cell disease in Kisangani, Democratic Republic of the Congo: an update.
Autorzy:
Kasai ET; Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Gulbis B; Department of Clinical Chemistry, Erasmus Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Ntukamunda JK; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Bours V; Biochemical Genetics Laboratory, Human Genetics, CHU of Liège, University of Liège, Liège, Belgium.
Batina Agasa S; Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Marini Djang'eing'a R; Department of Clinical Chemistry, Erasmus Hospital, Université Libre de Bruxelles, Brussels, Belgium.; Laboratory of Analytical Pharmaceutical Chemistry, Faculty of Medicine, University of Liège, Liège, Belgium.
Boemer F; Biochemical Genetics Laboratory, Human Genetics, CHU of Liège, University of Liège, Liège, Belgium.
Katenga Bosunga G; Department of Obstetrics and Gynecology, Kisangani University Clinics, University of Kisangani, Kisangani, The Democratic Republic of the Congo.
Ngbonda Dauly N; Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Sokoni Vutseme J; Department of Anthropology, Faculty of Social, Administrative and Political Sciences, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Boso Mokili B; Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Alworong'a Opara JP; Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2213043.
Typ publikacji:
Journal Article
MeSH Terms:
Neonatal Screening*
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/epidemiology
Anemia, Sickle Cell*/genetics
Infant ; Infant, Newborn ; Child ; Humans ; Democratic Republic of the Congo/epidemiology ; Hemoglobin, Sickle/genetics ; Point-of-Care Testing ; Hemoglobin A
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An innovative intervention for the prevention of vaso-occlusive episodes in sickle cell disease.
Autorzy:
Jeon WJ; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Joung B; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Moon JH; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Hino C; Department of Internal Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, USA.
Park D; Department of Internal Medicine, School of Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Pham B; Department of Internal Medicine, School of Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Castillo DR; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Chong E; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Kaur S; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
Grismore C; Director of Sickle Cell Servies, Loma Linda University Medical Center, Loma Linda, CA, USA.
Cao H; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2215575.
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/therapy
Humans ; Pain/etiology ; Pain/prevention & control ; Pain/drug therapy ; Hemoglobin, Sickle ; Pain Management/adverse effects ; Hydroxyurea/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
Autorzy:
Huang B; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Ghatge MS; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Donkor AK; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Musayev FN; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Deshpande TM; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.; Vertex Pharmaceutical Incorporated, Boston, MA 02210, USA.
Al-Awadh M; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Alhashimi RT; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Zhu H; Department of Medicine, Duke University Health System, Durham NC 27710, USA.; Department of Medicine, Durham VA Health Care System, Durham NC 27705, USA.
Omar AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Alsulaymanyah, Jeddah 21589, Saudi Arabia.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11884, Egypt.
Telen MJ; Department of Medicine, Duke University Health System, Durham NC 27710, USA.
Zhang Y; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
McMahon TJ; Department of Medicine, Duke University Health System, Durham NC 27710, USA.; Department of Medicine, Durham VA Health Care System, Durham NC 27705, USA.
Abdulmalik O; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Safo MK; Department of Medicinal Chemistry, The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Oct 12; Vol. 27 (20). Date of Electronic Publication: 2022 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Hemoglobin, Sickle*/metabolism
Anemia, Sickle Cell*/drug therapy
Anemia, Sickle Cell*/metabolism
Mice ; Animals ; Antisickling Agents/pharmacology ; Antisickling Agents/therapeutic use ; Nitric Oxide ; Aldehydes/pharmacology ; Nitrates ; Laminin ; Esters
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Modeling the public health impact of voxelotor in the management of sickle cell disease in France.
Autorzy:
Galacteros F; Unité des Maladies Génétiques du Globule Rouge, CHU Henri Mondor, Créteil, France.
Ethgen O; SERFAN Innovation, Namur, Belgium.; Department of Public Health, Epidemiology & Health Economics, University of Liège, Liège, Belgium.
Beillat M; Pfizer Biopharma Group, Pfizer, Paris, France.
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Źródło:
PloS one [PLoS One] 2023 Sep 13; Vol. 18 (9), pp. e0291211. Date of Electronic Publication: 2023 Sep 13 (Print Publication: 2023).
Typ publikacji:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Public Health*
Anemia, Sickle Cell*/complications
Anemia, Sickle Cell*/drug therapy
United States ; Humans ; Benzaldehydes ; Hemoglobin, Sickle ; France/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hb S ( HBB : c.20A>T) Characteristics by High Performance Liquid Chromatography in Patients with Sickle Cell Disease Receiving the Novel Agent Voxelotor.
Autorzy:
Tsitsikas DA; Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital, National Health Service Foundation Trust, London, UK.
Kamal M; Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital, National Health Service Foundation Trust, London, UK.
Braimoh A; Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital, National Health Service Foundation Trust, London, UK.
Benson S; Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital, National Health Service Foundation Trust, London, UK.
Abukar J; Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital, National Health Service Foundation Trust, London, UK.
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Źródło:
Hemoglobin [Hemoglobin] 2021 Nov; Vol. 45 (6), pp. 355-357. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/drug therapy
Hemoglobin, Sickle*/analysis
Benzaldehydes/adverse effects ; Chromatography, High Pressure Liquid ; Humans ; Pyrazines ; Pyrazoles
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quercetin Completely Ameliorates Hypoxia-Reoxygenation-Induced Pathophysiology Severity in NY1DD Transgenic Sickle Mice: Intrinsic Mild Steady State Pathophysiology of the Disease in NY1DD Is Also Reversed.
Autorzy:
Thangaswamy S; Division of Hematology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Branch CA; Magnetic Resonance Research Center, Department of Radiology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Ambadipudi K; Magnetic Resonance Research Center, Department of Radiology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
Acharya SA; Division of Hematology, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.
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Źródło:
Biomolecules [Biomolecules] 2021 Oct 06; Vol. 11 (10). Date of Electronic Publication: 2021 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell/*drug therapy
Hemoglobin, Sickle/*genetics
Oxygen/*metabolism
Quercetin/*pharmacology
Anemia, Sickle Cell/blood ; Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/pathology ; Animals ; Cell Hypoxia/drug effects ; Cell Hypoxia/genetics ; Disease Models, Animal ; Erythrocytes/drug effects ; Erythrocytes/pathology ; Genotype ; Hemoglobin, Sickle/ultrastructure ; Humans ; Mice ; Mice, Transgenic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biophysical Profiling of Sickle Cell Disease Using Holographic Cytometry and Deep Learning.
Autorzy:
Chen CX; BIOS Lab, Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Funkenbusch GT; BIOS Lab, Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Wax A; BIOS Lab, Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 25; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Deep Learning*
Anemia, Sickle Cell*/diagnosis
Hematologic Diseases*
Humans ; Hemoglobin, Sickle ; Erythrocytes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Newborn screening for sickle cell disease in Butembo and Beni: a pilot experience in a highland region of the Democratic Republic of Congo.
Autorzy:
Mumbere M; Department of Pediatrics, Faculty of Medicine, Catholic University of Graben, Butembo, Democratic Republic of the Congo.
Batina-Agasa S; Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Uvoya NA; Department of Pediatrics, Faculty of Medicine, University of Bunia, Bunia, Democratic Republic of the Congo.
Kasai ET; Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Kombi PK; Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
Djang'eing'a RM; Department of Pharmaceutical Sciences, Laboratory of Analytical Chemistry, Faculty of Medicine, University of Liège, Liège, Belgium.
Opara JA; Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of the Congo.
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Źródło:
The Pan African medical journal [Pan Afr Med J] 2023 May 24; Vol. 45, pp. 56. Date of Electronic Publication: 2023 May 24 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Anemia, Sickle Cell*/diagnosis
Anemia, Sickle Cell*/epidemiology
Ankle Injuries*
Infant, Newborn ; Humans ; Democratic Republic of the Congo/epidemiology ; Neonatal Screening ; Hemoglobin, Sickle
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes.
Autorzy:
Petersen JEV; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, United States of America.
Saelens JW; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, United States of America.
Freedman E; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, United States of America.
Turner L; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark.
Lavstsen T; Centre for Medical Parasitology, University of Copenhagen, Copenhagen, Denmark.
Fairhurst RM; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Diakité M; Malaria Research and Training Center, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali.
Taylor SM; Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, United States of America.; Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Jun 11; Vol. 17 (6), pp. e1009659. Date of Electronic Publication: 2021 Jun 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Hemoglobin, Sickle/*metabolism
Malaria, Falciparum/*genetics
Plasmodium falciparum/*genetics
Protozoan Proteins/*genetics
CD36 Antigens/metabolism ; Endothelial Protein C Receptor/metabolism ; Erythrocytes/parasitology ; Hemoglobin, Sickle/genetics ; Humans ; Malaria, Falciparum/metabolism ; Sickle Cell Trait/genetics ; Sickle Cell Trait/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Sickle Cell Hemoglobin Genotypes Affect Malaria Parasite Growth and Correlate with Exosomal miR-451a and let-7i-5p Levels.
Autorzy:
Oxendine Harp K; Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Bashi A; Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Botchway F; Department of Pathology, Korle-Bu Teaching Hospital, University of Ghana Medical School, Accra P.O. Box 4236, Ghana.
Addo-Gyan D; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra P.O. Box LG581, Ghana.
Tetteh-Tsifoanya M; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra P.O. Box LG581, Ghana.
Lamptey A; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra P.O. Box LG581, Ghana.
Djameh G; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra P.O. Box LG581, Ghana.
Iqbal SA; Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Lekpor C; Department of Pathology, Korle-Bu Teaching Hospital, University of Ghana Medical School, Accra P.O. Box 4236, Ghana.
Banerjee S; Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Wilson MD; Department of Parasitology, Noguchi Memorial Institute for Medical Research, University of Ghana, Accra P.O. Box LG581, Ghana.
Dei-Adomakoh Y; Department of Haematology, Korle-Bu Teaching Hospital, Accra P.O. Box 77, Ghana.
Adjei AA; Department of Pathology, Korle-Bu Teaching Hospital, University of Ghana Medical School, Accra P.O. Box 4236, Ghana.
Stiles JK; Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Driss A; Department of Physiology, Morehouse School of Medicine, Atlanta, GA 30310, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 19; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Parasites*/metabolism
MicroRNAs*/genetics
Anemia, Sickle Cell*/genetics
Sickle Cell Trait*/genetics
Malaria*/genetics
Animals ; Humans ; Hemoglobins/metabolism ; Hemoglobin, Sickle/genetics ; Hemoglobin, Sickle/metabolism ; Genotype ; Biomarkers ; Hemoglobin A/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of α subunit substitutions on the oxidation of βCys93 and the stability of sickle cell hemoglobin.
Autorzy:
Hicks W; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Meng F; Hemoglobin Oxygen Therapeutics, Souderton, Pennsylvania, USA.
Kassa T; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
Alayash AI; Laboratory of Biochemistry and Vascular Biology, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, Maryland, USA.
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Źródło:
Redox report : communications in free radical research [Redox Rep] 2020 Dec; Vol. 25 (1), pp. 95-103.
Typ publikacji:
Journal Article
MeSH Terms:
Cysteine/*genetics
Hemoglobin, Sickle/*chemistry
Hemoglobin, Sickle/*genetics
Amino Acid Substitution ; Chromatography, High Pressure Liquid ; Chromatography, Reverse-Phase ; Heme/chemistry ; Heme/genetics ; Hemoglobin, Sickle/metabolism ; Humans ; Hydrogen Peroxide/chemistry ; Isoelectric Focusing ; Mass Spectrometry ; Mutation ; Oxidation-Reduction ; Oxidative Stress ; Protein Stability ; Protein Subunits
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biomarkers of oxidative stress and its nexus with haemoglobin variants and adverse foeto-maternal outcome among women with preeclampsia in a Ghanaian population: A multi-centre prospective study.
Autorzy:
Abdul G; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; University Clinic, University Health Directorate, University of Energy and Natural Resources, Sunyani, Ghana.
Osei-Wusu W; Department of Medical Diagnostics, College of Health and Wellbeing, Kintampo, Ghana.
Asare GA; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Department of Medical Diagnostics, College of Health and Wellbeing, Kintampo, Ghana.
Daud S; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Department of Haematology, Faculty of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Opoku S; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Tamakloe VCKT; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Frimpong J; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Sackey B; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Boadu WIO; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Paintsil V; Department of Child Health, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Annani-Akollor ME; Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Wiafe YA; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Anto EO; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.; Centre for Precision Health, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia.
Addai-Mensah O; Department of Medical Diagnostics, Faculty of Allied Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
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Źródło:
PloS one [PLoS One] 2023 Mar 30; Vol. 18 (3), pp. e0283638. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Pre-Eclampsia*/epidemiology
HELLP Syndrome*
Premature Birth*
Jaundice, Neonatal*
Postpartum Hemorrhage*/epidemiology
Pregnancy ; Female ; Humans ; Infant, Newborn ; Ghana/epidemiology ; Prospective Studies ; Hemoglobin, Sickle ; Oxidative Stress ; Biomarkers ; Ascorbic Acid
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A high-throughput newborn screening approach for SCID, SMA, and SCD combining multiplex qPCR and tandem mass spectrometry.
Autorzy:
Tesorero R; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Janda J; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Hörster F; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Feyh P; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Mütze U; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Hauke J; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Schwarz K; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Kunz JB; Department of Pediatric Oncology, Hematology, Oncology and Immunology, University of Heidelberg, Heidelberg, Germany.
Hoffmann GF; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
Okun JG; Department of General Pediatrics, Division for Neuropediatrics and Metabolic Medicine, Center for Child and Adolescent Medicine and Dietmar Hopp Metabolic Center, University Hospital Heidelberg, Heidelberg, Germany.
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Źródło:
PloS one [PLoS One] 2023 Mar 10; Vol. 18 (3), pp. e0283024. Date of Electronic Publication: 2023 Mar 10 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Severe Combined Immunodeficiency*
Anemia, Sickle Cell*
Muscular Atrophy, Spinal*/genetics
Humans ; Infant, Newborn ; Neonatal Screening/methods ; Tandem Mass Spectrometry ; Hemoglobin, Sickle ; DNA
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 364

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