- Tytuł:
- Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity.
- Autorzy:
- Źródło:
- Neural plasticity [Neural Plast] 2021 May 29; Vol. 2021, pp. 9979157. Date of Electronic Publication: 2021 May 29 (Print Publication: 2021).
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Clusterin/*deficiency
Hair Cells, Auditory/*physiology
Hearing Loss, Sensorineural/*prevention & control
Presbycusis/*prevention & control
Animals ; Auditory Threshold ; Base Sequence ; CRISPR-Cas Systems ; Cellular Senescence ; Clusterin/biosynthesis ; Clusterin/genetics ; Clusterin/physiology ; Drug Synergism ; Evoked Potentials, Auditory, Brain Stem ; Furosemide/administration & dosage ; Furosemide/toxicity ; Hair Cells, Auditory/drug effects ; Hearing Loss, Sensorineural/chemically induced ; Kanamycin/administration & dosage ; Kanamycin/toxicity ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Organ Culture Techniques ; Organ of Corti/pathology ; Otoacoustic Emissions, Spontaneous ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics
Czasopismo naukowe