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Tytuł :
Environmental Sorption Behavior of Ionic and Ionizable Organic Chemicals.
Autorzy :
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Leipzig, Germany.
Goss KU; Helmholtz Centre for Environmental Research UFZ, Leipzig, Germany. .; Institute of Chemistry, University of Halle-Wittenberg, Halle, Germany. .
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Źródło :
Reviews of environmental contamination and toxicology [Rev Environ Contam Toxicol] 2021; Vol. 253, pp. 43-64.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Adsorption*
Organic Chemicals*
Soil*
Bioaccumulation ; Cations
Czasopismo naukowe
Tytuł :
Trout and Human Plasma Protein Binding of Selected Pharmaceuticals Informs the Fish Plasma Model.
Autorzy :
Henneberger L; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Klüver N; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Mühlenbrink M; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Escher B; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Tübingen, Germany.
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Źródło :
Environmental toxicology and chemistry [Environ Toxicol Chem] 2020 Nov 17. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines.
Autorzy :
Lee J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Braun G; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Scholz S; Department of Bioanalytical Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Scharrenbergstrasse 94-96, DE-72076 Tübingen, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2021 Sep 20; Vol. 34 (9), pp. 2100-2109. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Suspended Particulate Matter-A Source or Sink for Chemical Mixtures of Organic Micropollutants in a Small River under Baseflow Conditions?
Autorzy :
Niu L
Ahlheim J
Glaser C; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Gunold R
Henneberger L
König M
Krauss M
Schwientek M; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Zarfl C; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Escher BI; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, 04318 Leipzig, Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2021 Apr 20; Vol. 55 (8), pp. 5106-5116. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Rivers*
Water Pollutants, Chemical*/analysis
China ; Environmental Monitoring ; Fresh Water ; Geologic Sediments ; Particulate Matter/analysis
Czasopismo naukowe
Tytuł :
Quantitative In Vitro -to- In Vivo Extrapolation: Nominal versus Freely Dissolved Concentration.
Autorzy :
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Huchthausen J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Wojtysiak N; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2021 Apr 19; Vol. 34 (4), pp. 1175-1182. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Assay*
Pharmaceutical Preparations/*analysis
Humans
Czasopismo naukowe
Tytuł :
Setting the baseline in in vitro bioassays
Autorzy :
Rscher, B.
Fischer, F. C.
Glauch, L.
Henneberger, L.
Koenig, M.
Mayer, Philipp
Schlichting, R.
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Źródło :
Rscher, B, Fischer, F C, Glauch, L, Henneberger, L, Koenig, M, Mayer, P & Schlichting, R 2019, Setting the baseline in in vitro bioassays . in SETAC Europe 29th Annual Meeting - Abstract Book ., 75, Society of Environmental Toxicology and Chemistry, pp. 18-18, SETAC Europe 29th annual meeting, Helsinki, Finland, 26/05/2019 .
Opis pliku :
application/pdf
Tytuł :
Optimization of a pre-metabolization procedure using rat liver S9 and cell-extracted S9 in the Ames fluctuation test.
Autorzy :
Shao Y; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany; Key Laboratory of the Three Gorges Reservoir Eco-environment, Ministry of Education, Chongqing University, Shazheng street 174, Shapingba, 400044 Chongqing, China. Electronic address: .
Schiwy A; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany; Department of Evolutionary Ecology and Ecotoxicology, Goethe University, Max-von-Laue-Str. 13, 60438 Frankfurt/Main, Germany.
Glauch L; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany.
Henneberger L; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany.
König M; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany.
Mühlenbrink M; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany.
Xiao H; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany.
Thalmann B; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany.
Schlichting R; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany.
Hollert H; Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany; Department of Evolutionary Ecology and Ecotoxicology, Goethe University, Max-von-Laue-Str. 13, 60438 Frankfurt/Main, Germany.
Escher BI; UFZ - Helmholtz Centre for Environmental Research, Department of Cell Toxicology, Permoser Str. 15, 04318 Leipzig, Germany; EWOMIS GmbH, Schießstraße 26c, 63486 Bruchköbel, Germany; Eberhard Karls University of Tübingen, Environmental Toxicology, Centre for Applied Geosciences, 72074 Tubingen, Germany.
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Źródło :
The Science of the total environment [Sci Total Environ] 2020 Dec 20; Vol. 749, pp. 141468. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mutagens*
Salmonella typhimurium*/genetics
Animals ; Biotransformation ; Cell Extracts/pharmacology ; Liver ; Microsomes, Liver/metabolism ; Mutagenicity Tests ; Rats
Czasopismo naukowe
Tytuł :
Cellular Metabolism in High-Throughput In Vitro Reporter Gene Assays and Implications for the Quantitative In Vitro - In Vivo Extrapolation.
Autorzy :
Fischer FC; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Abele C; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Henneberger L; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Klüver N; Department Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
König M; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Mühlenbrink M; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Schlichting R; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Escher BI; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.; Centre for Applied Geoscience, Eberhard Karls University Tübingen, 72074 Tübingen, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1770-1779. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
Models, Biological*
Benzopyrenes/*pharmacology
Cytochrome P-450 CYP1A1/*genetics
Cytochrome P-450 CYP1A1/*metabolism
Genes, Reporter ; HEK293 Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays.
Autorzy :
Huchthausen J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Mühlenbrink M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, 72074 Tübingen, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1845-1854. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay/*methods
Organic Chemicals/*toxicity
Humans ; Liposomes/chemistry ; MCF-7 Cells ; Oxidative Stress/drug effects ; PPAR gamma/metabolism ; Serum Albumin, Bovine/chemistry ; Solid Phase Microextraction ; Water/chemistry
Czasopismo naukowe
Tytuł :
Cytotoxicity Burst? Differentiating Specific from Nonspecific Effects in Tox21 in Vitro Reporter Gene Assays.
Autorzy :
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Tübingen, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
Fischer FC; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
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Źródło :
Environmental health perspectives [Environ Health Perspect] 2020 Jul; Vol. 128 (7), pp. 77007. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
Toxicity Tests/*methods
Genes, Reporter ; Humans ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Experimental Validation of Mass Balance Models for in Vitro Cell-Based Bioassays.
Autorzy :
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Heinrich DJ; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
Teixeira A; Safety & Environmental Assurance Centre , Colworth Science Park , Sharnbrook , Bedfordshire MK44 1LQ , U.K.
Nicol B; Safety & Environmental Assurance Centre , Colworth Science Park , Sharnbrook , Bedfordshire MK44 1LQ , U.K.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2020 Jan 21; Vol. 54 (2), pp. 1120-1127. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Organic Chemicals*
Serum Albumin, Bovine*
Biological Assay ; Hydrophobic and Hydrophilic Interactions ; Water
Czasopismo naukowe
Tytuł :
How To Improve the Dosing of Chemicals in High-Throughput in Vitro Mammalian Cell Assays.
Autorzy :
Fischer FC; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2019 Aug 19; Vol. 32 (8), pp. 1462-1468. Date of Electronic Publication: 2019 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
High-Throughput Screening Assays*
Culture Media/*analysis
Animals ; Cell Survival/drug effects ; Culture Media/pharmacology ; Databases, Chemical ; Dose-Response Relationship, Drug ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł :
Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays.
Autorzy :
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany. luise.henneberger@ufz.de.
Mühlenbrink M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Fischer FC; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, 72074, Tübingen, Germany.
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Źródło :
Archives of toxicology [Arch Toxicol] 2019 Aug; Vol. 93 (8), pp. 2295-2305. Date of Electronic Publication: 2019 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay/*methods
Solid Phase Microextraction/*methods
Cell Survival/drug effects ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; In Vitro Techniques ; Oxidative Stress/drug effects ; PPAR gamma/metabolism ; Solubility
Czasopismo naukowe
Tytuł :
Combined Ion-Trapping and Mass Balance Models To Describe the pH-Dependent Uptake and Toxicity of Acidic and Basic Pharmaceuticals in Zebrafish Embryos ( Danio rerio).
Autorzy :
Bittner L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Klüver N; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Zarfl C; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2019 Jul 02; Vol. 53 (13), pp. 7877-7886. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Water Pollutants, Chemical*
Zebrafish*
Animals ; Diclofenac ; Embryo, Nonmammalian ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł :
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Autorzy :
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2019 Jan 22; Vol. 32 (1), pp. 168-178. Date of Electronic Publication: 2019 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid Phase Microextraction*
Phospholipids/*chemistry
Serum Albumin, Bovine/*chemistry
2,4-Dichlorophenoxyacetic Acid/analysis ; Animals ; Cattle ; Cells, Cultured ; Diclofenac/analysis ; Genistein/analysis ; HEK293 Cells ; Humans ; Ibuprofen/analysis ; Kinetics ; Liposomes/chemistry ; Naproxen/analysis ; Torsemide/analysis ; Warfarin/analysis
Czasopismo naukowe
Tytuł :
Application of Experimental Polystyrene Partition Constants and Diffusion Coefficients to Predict the Sorption of Neutral Organic Chemicals to Multiwell Plates in in Vivo and in Vitro Bioassays.
Autorzy :
Fischer FC; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Cirpka OA; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
Goss KU; Helmholtz Centre for Environmental Research - UFZ , Department Analytical Environmental Chemistry , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2018 Nov 20; Vol. 52 (22), pp. 13511-13522. Date of Electronic Publication: 2018 Oct 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organic Chemicals*
Polystyrenes*
Animals ; Biological Assay ; Kinetics ; Plastics
Czasopismo naukowe
Tytuł :
Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy.
Autorzy :
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Abele C; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Droge STJ; Institute for Biodiversity and Ecosystem Dynamics , University of Amsterdam , Science Park 904 , 1098 XH Amsterdam , Netherlands.
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
König M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Scholz S; Department of Bioanalytical Ecotoxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2018 Aug 20; Vol. 31 (8), pp. 646-657. Date of Electronic Publication: 2018 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hazardous Substances/*pharmacokinetics
Microscopy, Fluorescence/*methods
Animals ; Area Under Curve ; Cell Line ; Cell Line, Tumor ; Culture Media ; Genes, Reporter ; Humans ; In Vitro Techniques ; Thermodynamics
Czasopismo naukowe
Tytuł :
Equilibrium biopartitioning of organic anions - A case study for humans and fish.
Autorzy :
Goss KU; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany; University of Halle-Wittenberg, Institute of Chemistry, Kurt-Mothes-Str. 2, D-06120 Halle, Germany. Electronic address: .
Bittermann K; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany.
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Department of Cell Toxicology, Permoserstr. 15, D-04318 Leipzig, Germany.
Linden L; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany.
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Źródło :
Chemosphere [Chemosphere] 2018 May; Vol. 199, pp. 174-181. Date of Electronic Publication: 2018 Feb 06.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Albumins/*metabolism
Fishes/*metabolism
Organic Chemicals/*metabolism
Water Pollutants, Chemical/*metabolism
Absorption, Physiological ; Animals ; Anions ; Humans ; Hydrogen-Ion Concentration ; Membrane Lipids/metabolism ; Organ Specificity ; Organic Chemicals/toxicity ; Species Specificity ; Toxicokinetics ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Modeling Exposure in the Tox21 in Vitro Bioassays.
Autorzy :
Fischer FC; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Henneberger L; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
König M; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Bittermann K; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Linden L; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Goss KU; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Escher BI; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2017 May 15; Vol. 30 (5), pp. 1197-1208. Date of Electronic Publication: 2017 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
Environmental Exposure*
Models, Theoretical*
Toxicity Tests*
Genes, Reporter ; HEK293 Cells ; Hep G2 Cells ; High-Throughput Screening Assays ; Humans ; In Vitro Techniques ; Quantitative Structure-Activity Relationship
Czasopismo naukowe

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