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Wyszukujesz frazę ""Henneberger L"" wg kryterium: Wszystkie pola


Tytuł:
Trout and Human Plasma Protein Binding of Selected Pharmaceuticals Informs the Fish Plasma Model.
Autorzy:
Henneberger L; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Klüver N; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Mühlenbrink M; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Escher B; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Tübingen, Germany.
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Źródło:
Environmental toxicology and chemistry [Environ Toxicol Chem] 2022 Mar; Vol. 41 (3), pp. 559-568. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Oncorhynchus mykiss*/metabolism
Water Pollutants, Chemical*/metabolism
Animals ; Humans ; Pharmaceutical Preparations/metabolism ; Plasma/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł:
High-Throughput Assessment of the Abiotic Stability of Test Chemicals in In Vitro Bioassays.
Autorzy:
Huchthausen J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research─UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research─UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany.
Mälzer S; Department of Cell Toxicology, Helmholtz Centre for Environmental Research─UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany.
Nicol B; Safety and Environmental Assurance Centre, Unilever, Colworth House, Sharnbrook, Bedford MK44 1LQ, U.K.
Sparham C; Safety and Environmental Assurance Centre, Unilever, Colworth House, Sharnbrook, Bedford MK44 1LQ, U.K.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research─UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, DE-72076 Tübingen, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2022 May 16; Vol. 35 (5), pp. 867-879. Date of Electronic Publication: 2022 Apr 08.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Assay*/methods
Solid Phase Microextraction*
Hydrolysis ; Photolysis ; Serum Albumin, Bovine/chemistry ; Water/chemistry
Czasopismo naukowe
Tytuł:
Critical Membrane Concentration and Mass-Balance Model to Identify Baseline Cytotoxicity of Hydrophobic and Ionizable Organic Chemicals in Mammalian Cell Lines.
Autorzy:
Lee J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Braun G; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Scholz S; Department of Bioanalytical Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstrasse 15, DE-04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Scharrenbergstrasse 94-96, DE-72076 Tübingen, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2021 Sep 20; Vol. 34 (9), pp. 2100-2109. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Organic Chemicals/*toxicity
Cell Line, Tumor ; Humans ; Hydrophobic and Hydrophilic Interactions ; Models, Chemical ; Organic Chemicals/chemistry ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Suspended Particulate Matter-A Source or Sink for Chemical Mixtures of Organic Micropollutants in a Small River under Baseflow Conditions?
Autorzy:
Niu L
Ahlheim J
Glaser C; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Gunold R
Henneberger L
König M
Krauss M
Schwientek M; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Zarfl C; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
Escher BI; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, 04318 Leipzig, Germany.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2021 Apr 20; Vol. 55 (8), pp. 5106-5116. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Rivers*
Water Pollutants, Chemical*/analysis
China ; Environmental Monitoring ; Fresh Water ; Geologic Sediments ; Particulate Matter/analysis
Czasopismo naukowe
Tytuł:
Quantitative In Vitro -to- In Vivo Extrapolation: Nominal versus Freely Dissolved Concentration.
Autorzy:
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Huchthausen J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Wojtysiak N; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Schnarrenbergstr. 94-96, 72076 Tübingen, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2021 Apr 19; Vol. 34 (4), pp. 1175-1182. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Assay*
Pharmaceutical Preparations/*analysis
Humans
Czasopismo naukowe
Tytuł:
Experimental Exposure Assessment of Ionizable Organic Chemicals in In Vitro Cell-Based Bioassays.
Autorzy:
Huchthausen J; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Mühlenbrink M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, 72074 Tübingen, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1845-1854. Date of Electronic Publication: 2020 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay/*methods
Organic Chemicals/*toxicity
Humans ; Liposomes/chemistry ; MCF-7 Cells ; Oxidative Stress/drug effects ; PPAR gamma/metabolism ; Serum Albumin, Bovine/chemistry ; Solid Phase Microextraction ; Water/chemistry
Czasopismo naukowe
Tytuł:
Cellular Metabolism in High-Throughput In Vitro Reporter Gene Assays and Implications for the Quantitative In Vitro - In Vivo Extrapolation.
Autorzy:
Fischer FC; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Abele C; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Henneberger L; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Klüver N; Department Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
König M; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Mühlenbrink M; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Schlichting R; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
Escher BI; Department Cell Toxicology, Helmholtz Centre for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.; Centre for Applied Geoscience, Eberhard Karls University Tübingen, 72074 Tübingen, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2020 Jul 20; Vol. 33 (7), pp. 1770-1779. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay*
Models, Biological*
Benzopyrenes/*pharmacology
Cytochrome P-450 CYP1A1/*genetics
Cytochrome P-450 CYP1A1/*metabolism
Genes, Reporter ; HEK293 Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Cytotoxicity Burst? Differentiating Specific from Nonspecific Effects in Tox21 in Vitro Reporter Gene Assays.
Autorzy:
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, Tübingen, Germany.
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
Fischer FC; Department of Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
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Źródło:
Environmental health perspectives [Environ Health Perspect] 2020 Jul; Vol. 128 (7), pp. 77007. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay*
Toxicity Tests/*methods
Genes, Reporter ; Humans ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Experimental Validation of Mass Balance Models for in Vitro Cell-Based Bioassays.
Autorzy:
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Heinrich DJ; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
Teixeira A; Safety & Environmental Assurance Centre , Colworth Science Park , Sharnbrook , Bedfordshire MK44 1LQ , U.K.
Nicol B; Safety & Environmental Assurance Centre , Colworth Science Park , Sharnbrook , Bedfordshire MK44 1LQ , U.K.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research-UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2020 Jan 21; Vol. 54 (2), pp. 1120-1127. Date of Electronic Publication: 2020 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Organic Chemicals*
Serum Albumin, Bovine*
Biological Assay ; Hydrophobic and Hydrophilic Interactions ; Water
Czasopismo naukowe
Tytuł:
How To Improve the Dosing of Chemicals in High-Throughput in Vitro Mammalian Cell Assays.
Autorzy:
Fischer FC; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2019 Aug 19; Vol. 32 (8), pp. 1462-1468. Date of Electronic Publication: 2019 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay*
High-Throughput Screening Assays*
Culture Media/*analysis
Animals ; Cell Survival/drug effects ; Culture Media/pharmacology ; Databases, Chemical ; Dose-Response Relationship, Drug ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł:
Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays.
Autorzy:
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany. luise.henneberger@ufz.de.
Mühlenbrink M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Fischer FC; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, 72074, Tübingen, Germany.
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Źródło:
Archives of toxicology [Arch Toxicol] 2019 Aug; Vol. 93 (8), pp. 2295-2305. Date of Electronic Publication: 2019 Jun 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay/*methods
Solid Phase Microextraction/*methods
Cell Survival/drug effects ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; In Vitro Techniques ; Oxidative Stress/drug effects ; PPAR gamma/metabolism ; Solubility
Czasopismo naukowe
Tytuł:
Combined Ion-Trapping and Mass Balance Models To Describe the pH-Dependent Uptake and Toxicity of Acidic and Basic Pharmaceuticals in Zebrafish Embryos ( Danio rerio).
Autorzy:
Bittner L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Klüver N; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Zarfl C; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2019 Jul 02; Vol. 53 (13), pp. 7877-7886. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Water Pollutants, Chemical*
Zebrafish*
Animals ; Diclofenac ; Embryo, Nonmammalian ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł:
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Autorzy:
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2019 Jan 22; Vol. 32 (1), pp. 168-178. Date of Electronic Publication: 2019 Jan 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Solid Phase Microextraction*
Phospholipids/*chemistry
Serum Albumin, Bovine/*chemistry
2,4-Dichlorophenoxyacetic Acid/analysis ; Animals ; Cattle ; Cells, Cultured ; Diclofenac/analysis ; Genistein/analysis ; HEK293 Cells ; Humans ; Ibuprofen/analysis ; Kinetics ; Liposomes/chemistry ; Naproxen/analysis ; Torsemide/analysis ; Warfarin/analysis
Czasopismo naukowe
Tytuł:
Application of Experimental Polystyrene Partition Constants and Diffusion Coefficients to Predict the Sorption of Neutral Organic Chemicals to Multiwell Plates in in Vivo and in Vitro Bioassays.
Autorzy:
Fischer FC; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Cirpka OA; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
Goss KU; Helmholtz Centre for Environmental Research - UFZ , Department Analytical Environmental Chemistry , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2018 Nov 20; Vol. 52 (22), pp. 13511-13522. Date of Electronic Publication: 2018 Oct 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Organic Chemicals*
Polystyrenes*
Animals ; Biological Assay ; Kinetics ; Plastics
Czasopismo naukowe
Tytuł:
Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy.
Autorzy:
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Abele C; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Droge STJ; Institute for Biodiversity and Ecosystem Dynamics , University of Amsterdam , Science Park 904 , 1098 XH Amsterdam , Netherlands.
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
König M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Scholz S; Department of Bioanalytical Ecotoxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2018 Aug 20; Vol. 31 (8), pp. 646-657. Date of Electronic Publication: 2018 Jul 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hazardous Substances/*pharmacokinetics
Microscopy, Fluorescence/*methods
Animals ; Area Under Curve ; Cell Line ; Cell Line, Tumor ; Culture Media ; Genes, Reporter ; Humans ; In Vitro Techniques ; Thermodynamics
Czasopismo naukowe
Tytuł:
Modeling Exposure in the Tox21 in Vitro Bioassays.
Autorzy:
Fischer FC; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Henneberger L; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
König M; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Bittermann K; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Linden L; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Goss KU; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Escher BI; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
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Źródło:
Chemical research in toxicology [Chem Res Toxicol] 2017 May 15; Vol. 30 (5), pp. 1197-1208. Date of Electronic Publication: 2017 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biological Assay*
Environmental Exposure*
Models, Theoretical*
Toxicity Tests*
Genes, Reporter ; HEK293 Cells ; Hep G2 Cells ; High-Throughput Screening Assays ; Humans ; In Vitro Techniques ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
General baseline toxicity QSAR for nonpolar, polar and ionisable chemicals and their mixtures in the bioluminescence inhibition assay with Aliivibrio fischeri.
Autorzy:
Escher BI; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. Tübingen, Environmental Toxicology, Center for Applied Geosciences, 72074 Tübingen, Germany.
Baumer A; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. , Leipzig University, Eilenburger Str. 15a, 04317 Leipzig, Germany.
Bittermann K; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Henneberger L; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
König M; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Kühnert C; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Klüver N; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
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Źródło:
Environmental science. Processes & impacts [Environ Sci Process Impacts] 2017 Mar 22; Vol. 19 (3), pp. 414-428.
Typ publikacji:
Journal Article
MeSH Terms:
Quantitative Structure-Activity Relationship*
Aliivibrio fischeri/*drug effects
Organic Chemicals/*toxicity
Water Pollutants, Chemical/*toxicity
Biological Assay/methods ; Hazardous Substances/chemistry ; Hazardous Substances/toxicity ; Hydrophobic and Hydrophilic Interactions ; Luminescent Measurements ; Models, Theoretical ; Organic Chemicals/chemistry ; Solubility ; Water ; Water Pollutants, Chemical/chemistry
Czasopismo naukowe
Tytuł:
Partitioning of Organic Ions to Muscle Protein: Experimental Data, Modeling, and Implications for in Vivo Distribution of Organic Ions.
Autorzy:
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.
Goss KU; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Institute of Chemistry, University of Halle-Wittenberg , Kurt-Mothes-Strasse 2, D-06120 Halle, Germany.
Endo S; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Urban Research Plaza & Graduate School of Engineering, Osaka City University , Sugimoto 3-3-138, Sumiyoshi-ku, 558-8585 Osaka, Japan.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2016 Jul 05; Vol. 50 (13), pp. 7029-36. Date of Electronic Publication: 2016 Jun 21.
Typ publikacji:
Journal Article
MeSH Terms:
Muscle Proteins*
Organic Chemicals/*chemistry
Animals ; Ions ; Physical Phenomena ; Water/chemistry
Czasopismo naukowe
Tytuł:
Equilibrium Sorption of Structurally Diverse Organic Ions to Bovine Serum Albumin.
Autorzy:
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.
Goss KU; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; University of Halle-Wittenberg , Institute of Chemistry, Kurt-Mothes-Strasse 2, D-06120 Halle, Germany.
Endo S; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Osaka City University , Urban Research Plaza & Graduate School of Engineering, Sugimoto 3-3-138, Sumiyoshi-ku, 558-8585 Osaka, Japan.
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Źródło:
Environmental science & technology [Environ Sci Technol] 2016 May 17; Vol. 50 (10), pp. 5119-26. Date of Electronic Publication: 2016 May 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Organic Chemicals/*chemistry
Serum Albumin, Bovine/*chemistry
Cations ; Serum Albumin ; Water/chemistry
Czasopismo naukowe
Tytuł:
Concentration and Properties of the Adrenocorticotrophic Substance in Female Human Urine
Autorzy:
Kaufman S
Williamson Mb
Henneberger L
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Temat:
General Biochemistry, Genetics and Molecular Biology
Endocrinology
medicine.medical_specialty
medicine
Internal medicine
Urine
business.industry
business
Źródło:
Experimental Biology and Medicine. 63:191-194
Dostępność:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b30b8d246862d264cb5a3c147832868
Tytuł:
Setting the baseline in in vitro bioassays
Autorzy:
Rscher, B.
Fischer, F. C.
Glauch, L.
Henneberger, L.
Koenig, M.
Philipp Mayer
Schlichting, R.
Pokaż więcej
Źródło:
Technical University of Denmark Orbit
Rscher, B, Fischer, F C, Glauch, L, Henneberger, L, Koenig, M, Mayer, P & Schlichting, R 2019, Setting the baseline in in vitro bioassays . in SETAC Europe 29th Annual Meeting-Abstract Book ., 75, Society of Environmental Toxicology and Chemistry, pp. 18-18, SETAC Europe 29th annual meeting, Helsinki, Finland, 26/05/2019 .
Opis pliku:
application/pdf
Dostępność:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c8b22f8a56baac190fcab44a37210f7
https://orbit.dtu.dk/en/publications/cce26aa5-8815-4520-98b5-d373f13b3b73
Tytuł:
Maternal Pre-Pregnancy Obesity and Gestational Diabetes Mellitus Increase the Risk of Childhood Obesity.
Autorzy:
Choi, Mi Jin
Yu, Juyoun
Choi, Jimi
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Temat:
CHILDHOOD obesity -- Risk factors
CONFIDENCE intervals
PREGNANT women
RISK assessment
DESCRIPTIVE statistics
DISEASE prevalence
RESEARCH funding
GESTATIONAL diabetes
OBESITY in women
STATISTICAL models
LOGISTIC regression analysis
BODY mass index
DATA analysis software
Źródło:
Children; Jul2022, Vol. 9 Issue 7, pN.PAG-N.PAG, 11p
Terminy geograficzne:
SOUTH Korea
Czasopismo naukowe
Tytuł:
Natural Bioactive Products and Alzheimer's Disease Pathology: Lessons from Caenorhabditis elegans Transgenic Models.
Autorzy:
Navarro-Hortal, María D.
Romero-Márquez, Jose M.
Osta, Safa
Jiménez-Trigo, Victoria
Muñoz-Ollero, Pedro
Varela-López, Alfonso
Pokaż więcej
Temat:
TRANSGENIC mice
ALZHEIMER'S disease
CAENORHABDITIS elegans
PATHOLOGY
NATURAL products
DRUG target
CELL culture
Źródło:
Diseases; Jun2022, Vol. 10 Issue 2, p28, 35p
Czasopismo naukowe
Tytuł:
A DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive release and triple modal imaging guided photothermal synergistic chemotherapy.
Autorzy:
Xu, Pengcheng (AUTHOR)
Wang, Ru (AUTHOR)
Yang, Wenqian (AUTHOR)
Liu, Yanyan (AUTHOR)
He, Dongsheng (AUTHOR)
Ye, Zixuan (AUTHOR)
Chen, Daquan (AUTHOR)
Ding, Yuan (AUTHOR)
Tu, Jiasheng (AUTHOR)
Shen, Yan (AUTHOR)
Pokaż więcej
Źródło:
Journal of Nanobiotechnology. 4/27/2021, Vol. 19 Issue 1, p1-19. 19p.
Czasopismo naukowe
Tytuł:
Estimating the Equilibrium Distribution of Perfluoroalkyl Acids and 4 of Their Alternatives in Mammals.
Autorzy:
Allendorf F; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Goss KU; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Institute of Chemistry, University of Halle-Wittenberg, Halle, Germany.
Ulrich N; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
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Źródło:
Environmental toxicology and chemistry [Environ Toxicol Chem] 2021 Mar; Vol. 40 (3), pp. 910-920. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alkanesulfonic Acids*
Fluorocarbons*/analysis
Water Pollutants, Chemical*/analysis
Animals ; Mammals ; Rats
Czasopismo naukowe
Tytuł:
Hepatic IGF2/H19 Epigenetic Alteration Induced Glucose Intolerance in Gestational Diabetes Mellitus Offspring via FoxO1 Mediation.
Autorzy:
Jiang, Ying
Zhu, Hong
Chen, Zi
Yu, Yi-Chen
Guo, Xiao-Han
Chen, Yuan
Yang, Meng-Meng
Chen, Bang-Wu
Sagnelli, Matthew
Xu, Dong
Zhao, Bai-Hui
Luo, Qiong
Pokaż więcej
Temat:
GESTATIONAL diabetes
GLUCOSE intolerance
TYPE 2 diabetes
GLUCOSE tolerance tests
DIABETES in children
SECOND trimester of pregnancy
Źródło:
Frontiers in Endocrinology; 4/1/2022, Vol. 13, p1-11, 11p
Czasopismo naukowe
Tytuł:
Screening of the Toxicity of Polystyrene Nano- and Microplastics Alone and in Combination with Benzo(a)pyrene in Brine Shrimp Larvae and Zebrafish Embryos.
Autorzy:
Martínez-Álvarez, Ignacio
Le Menach, Karyn
Devier, Marie-Hélène
Cajaraville, Miren P.
Budzinski, Hélène
Orbea, Amaia
Pokaż więcej
Temat:
ZEBRA danio embryos
ARTEMIA
MICROPLASTICS
PERSISTENT pollutants
BRACHYDANIO
YOLK sac
LARVAE
Źródło:
Nanomaterials (2079-4991); Mar2022, Vol. 12 Issue 6, p941, 23p
Czasopismo naukowe
Tytuł:
Getting in control of persistent, mobile and toxic (PMT) and very persistent and very mobile (vPvM) substances to protect water resources: strategies from diverse perspectives.
Autorzy:
Hale, Sarah E.
Neumann, Michael
Schliebner, Ivo
Schulze, Jona
Averbeck, Frauke S.
Castell-Exner, Claudia
Collard, Marie
Drmač, Dunja
Hartmann, Julia
Hofman-Caris, Roberta
Hollender, Juliane
de Jonge, Martin
Kullick, Thomas
Lennquist, Anna
Letzel, Thomas
Nödler, Karsten
Pawlowski, Sascha
Reineke, Ninja
Rorije, Emiel
Scheurer, Marco
Pokaż więcej
Temat:
POISONS
WATER supply
ENVIRONMENTAL health
WATER quality
SUSTAINABLE design
DRINKING water
Źródło:
Environmental Sciences Europe; 3/8/2022, Vol. 34 Issue 1, p1-24, 24p
Przedsiębiorstwo/ jednostka:
EUROPEAN Commission
Czasopismo naukowe
Tytuł:
Effect-Based Trigger Values for Mixtures of Chemicals in Surface Water Detected with In Vitro Bioassays.
Autorzy:
Escher BI; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Center for Applied Geoscience, Eberhard Karls University of Tübingen, Tübingen, Germany.
Neale PA; Australian Rivers Institute, School of Environment and Science, Griffith University, Southport, Queensland, Australia.
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Źródło:
Environmental toxicology and chemistry [Environ Toxicol Chem] 2021 Feb; Vol. 40 (2), pp. 487-499. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Water Pollutants, Chemical*
Water Purification*
Biological Assay ; Environmental Monitoring ; Water Quality
Czasopismo naukowe
Tytuł:
σ‐Aromaticity‐Induced Stabilization of Heterometallic Supertetrahedral Clusters [Zn6Ge16].
Autorzy:
Xu, Hong‐Lei (AUTHOR)
Popov, Ivan A. (AUTHOR)
Tkachenko, Nikolay V. (AUTHOR)
Wang, Zi‐Chuan (AUTHOR)
Muñoz‐Castro, Alvaro (AUTHOR)
Boldyrev, Alexander I. (AUTHOR)
Sun, Zhong‐Ming (AUTHOR)
Pokaż więcej
Źródło:
Angewandte Chemie. 9/21/2020, Vol. 132 Issue 39, p17439-17443. 5p.
Czasopismo naukowe
Tytuł:
Estrogenic activity of food contact materials—evaluation of 20 chemicals using a yeast estrogen screen on HPTLC or 96-well plates.
Autorzy:
Bergmann, Alan J. (AUTHOR)
Simon, Eszter (AUTHOR)
Schifferli, Andrea (AUTHOR)
Schönborn, Andreas (AUTHOR)
Vermeirssen, Etiënne L. M. (AUTHOR)
Pokaż więcej
Źródło:
Analytical & Bioanalytical Chemistry. Jul2020, Vol. 412 Issue 19, p4527-4536. 10p.
Czasopismo naukowe
Tytuł:
Prenatal over‐ and undernutrition differentially program small intestinal growth, angiogenesis, absorptive capacity, and endocrine function in sheep.
Autorzy:
Khanal, Prabhat (AUTHOR)
D. Axel, Anne Marie (AUTHOR)
Safayi, Sina (AUTHOR)
Elbrønd, Vibeke S. (AUTHOR)
Nielsen, Mette O. (AUTHOR)
Pokaż więcej
Źródło:
Physiological Reports. Jun2020, Vol. 8 Issue 12, p1-20. 20p.
Czasopismo naukowe
Tytuł:
Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation.
Autorzy:
Loizou, George
McNally, Kevin
Paini, Alicia
Hogg, Alex
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Temat:
BISPHENOL A
PREGNANE X receptor
MARKOV chain Monte Carlo
HIGH throughput screening (Drug development)
EXTRAPOLATION
WORKFLOW software
WORKFLOW
Źródło:
Frontiers in Pharmacology; 2/11/2022, Vol. 13, p1-22, 22p
Przedsiębiorstwo/ jednostka:
EUROPEAN Food Safety Authority
Czasopismo naukowe
Tytuł:
Yolk-Water Partitioning of Neutral Organic Compounds in the Model Organism Danio rerio.
Autorzy:
Ulrich N; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Schweiger N; Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Pfennigsdorff A; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Scholz S; Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Goss KU; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Institute of Chemistry, University of Halle-Wittenberg, Halle, Germany.
Pokaż więcej
Źródło:
Environmental toxicology and chemistry [Environ Toxicol Chem] 2020 Aug; Vol. 39 (8), pp. 1506-1516. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Models, Biological*
Egg Yolk/*chemistry
Organic Chemicals/*chemistry
Water/*chemistry
Zebrafish/*metabolism
Animals ; Biomass ; Dialysis ; Egg Proteins/analysis ; Reproducibility of Results ; Temperature ; Volatile Organic Compounds/analysis ; Water Pollutants, Chemical/chemistry
Czasopismo naukowe
Tytuł:
Mutagenicity of the Danube River: The contribution of liquid phase and particulate suspended matter.
Autorzy:
Morales DA; School of Technology, State University of Campinas, Limeira, Sao Paulo, Brazil.
Massei R; Department Effect-Directed Analysis, Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany.
Schulze T; Department Effect-Directed Analysis, Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany.
Krauss M; Department Effect-Directed Analysis, Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany.
Brack W; Department Effect-Directed Analysis, Helmholtz Centre for Environmental Research GmbH, Leipzig, Germany.; Department of Evolutionary Ecology and Environmental Toxicology, Goethe University of Frankfurt, Frankfurt, Germany.
de Aragão Umbuzeiro G; School of Technology, State University of Campinas, Limeira, Sao Paulo, Brazil.
Pokaż więcej
Źródło:
Environmental and molecular mutagenesis [Environ Mol Mutagen] 2022 Mar; Vol. 63 (3), pp. 162-168. Date of Electronic Publication: 2022 Mar 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Particulate Matter*/toxicity
Rivers*/chemistry
Mutagenicity Tests ; Mutagens/toxicity ; Water
Czasopismo naukowe
Tytuł:
Pharmacokinetics and bioavailability of meloxicam in rainbow trout (Oncorhynchus mykiss) broodstock following intravascular, intramuscular, and oral administrations.
Autorzy:
Corum O; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Kastamonu, Kastamonu, Turkey.
Terzi E; Faculty of Fisheries, University of Kastamonu, Kastamonu, Turkey.
Durna Corum D; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Kastamonu, Kastamonu, Turkey.
Uney K; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey.
Pokaż więcej
Źródło:
Journal of veterinary pharmacology and therapeutics [J Vet Pharmacol Ther] 2022 Mar; Vol. 45 (2), pp. 213-219. Date of Electronic Publication: 2021 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Oncorhynchus mykiss*
Administration, Oral ; Animals ; Biological Availability ; Half-Life ; Injections, Intramuscular/veterinary ; Meloxicam
Czasopismo naukowe
Tytuł:
Identifying Chemicals and Mixtures of Potential Biological Concern Detected in Passive Samplers from Great Lakes Tributaries Using High‐Throughput Data and Biological Pathways.
Autorzy:
Alvarez, David A.
Corsi, Steven R.
De Cicco, Laura A.
Villeneuve, Daniel L.
Baldwin, Austin K.
Pokaż więcej
Temat:
PASSIVE sampling devices (Environmental sampling)
ENVIRONMENTAL toxicology
CHEMICAL potential
ORGANOCHLORINE pesticides
PUBLIC domain (Copyright law)
ODORS
CITRATES
HERBICIDES
Źródło:
Environmental Toxicology & Chemistry; Aug2021, Vol. 40 Issue 8, p2165-2182, 18p
Czasopismo naukowe
Tytuł:
Bacterial responses to background organic pollutants in the northeast subarctic Pacific Ocean.
Autorzy:
Martinez‐Varela, Alícia
Cerro‐Gálvez, Elena
Auladell, Adrià
Sharma, Shalabh
Moran, Mary Ann
Kiene, Ronald P.
Piña, Benjamí
Dachs, Jordi
Vila‐Costa, Maria
Pokaż więcej
Temat:
DISSOLVED organic matter
POLLUTANTS
GENE expression profiling
OCEAN
CONTINENTAL shelf
PLASTICIZERS
PLASTIC marine debris
Źródło:
Environmental Microbiology; Aug2021, Vol. 23 Issue 8, p4532-4546, 15p
Czasopismo naukowe

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