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Tytuł :
Concentration and properties of the adrenocorticotrophic substance in female human urine.
Autorzy :
WILLIAMSON MB
KAUFMAN S
HENNEBERGER L
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Źródło :
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) [Proc Soc Exp Biol Med] 1946 Oct; Vol. 63 (1), pp. 191-4.
Typ publikacji :
Journal Article
MeSH Terms :
Body Fluids*
Pituitary Diseases*
Adrenal Glands/*physiology
Pituitary Gland/*metabolism
Czasopismo naukowe
Tytuł :
Prevalence and predictors of overweight and insulin resistance in offspring of mothers with gestational diabetes mellitus.
Autorzy :
Boerschmann H; Forschergruppe Diabetes der Technischen Universität München, Munich, Germany.
Pflüger M
Henneberger L
Ziegler AG
Hummel S
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Źródło :
Diabetes care [Diabetes Care] 2010 Aug; Vol. 33 (8), pp. 1845-9. Date of Electronic Publication: 2010 Apr 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes, Gestational/*physiopathology
Insulin Resistance/*physiology
Overweight/*epidemiology
Prenatal Exposure Delayed Effects/*physiopathology
Child ; Child, Preschool ; Female ; Humans ; Male ; Mothers ; Overweight/etiology ; Pregnancy ; Prevalence
Czasopismo naukowe
Tytuł :
BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1.
Autorzy :
Winkler C; Institut fuer Diabetes forschung der Forschergruppe Diabetes e.V. at Helmholtz Center Munich, Neuherberg, Germany.
Bonifacio E
Grallert H
Henneberger L
Illig T
Ziegler AG
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Źródło :
Diabetes [Diabetes] 2010 Aug; Vol. 59 (8), pp. 2063-7. Date of Electronic Publication: 2010 May 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Mass Index*
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Cyclin-Dependent Kinase 5/*genetics
Diabetes Mellitus, Type 1/*genetics
Diabetes Mellitus, Type 2/*genetics
Homeodomain Proteins/*genetics
Transcription Factors/*genetics
Birth Weight/genetics ; Child ; Cohort Studies ; Fathers ; Female ; Germany ; Humans ; Male ; Mothers ; tRNA Methyltransferases
Czasopismo naukowe
Tytuł :
Equilibrium Sorption of Structurally Diverse Organic Ions to Bovine Serum Albumin.
Autorzy :
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.
Goss KU; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; University of Halle-Wittenberg , Institute of Chemistry, Kurt-Mothes-Strasse 2, D-06120 Halle, Germany.
Endo S; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Osaka City University , Urban Research Plaza & Graduate School of Engineering, Sugimoto 3-3-138, Sumiyoshi-ku, 558-8585 Osaka, Japan.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2016 May 17; Vol. 50 (10), pp. 5119-26. Date of Electronic Publication: 2016 May 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organic Chemicals/*chemistry
Serum Albumin, Bovine/*chemistry
Cations ; Serum Albumin ; Water/chemistry
Czasopismo naukowe
Tytuł :
Partitioning of Organic Ions to Muscle Protein: Experimental Data, Modeling, and Implications for in Vivo Distribution of Organic Ions.
Autorzy :
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.
Goss KU; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Institute of Chemistry, University of Halle-Wittenberg , Kurt-Mothes-Strasse 2, D-06120 Halle, Germany.
Endo S; Helmholtz Centre for Environmental Research UFZ, Permoserstrasse 15, D-04318 Leipzig, Germany.; Urban Research Plaza & Graduate School of Engineering, Osaka City University , Sugimoto 3-3-138, Sumiyoshi-ku, 558-8585 Osaka, Japan.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2016 Jul 05; Vol. 50 (13), pp. 7029-36. Date of Electronic Publication: 2016 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle Proteins*
Organic Chemicals/*chemistry
Animals ; Ions ; Physical Phenomena ; Water/chemistry
Czasopismo naukowe
Tytuł :
General baseline toxicity QSAR for nonpolar, polar and ionisable chemicals and their mixtures in the bioluminescence inhibition assay with Aliivibrio fischeri.
Autorzy :
Escher BI; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. Tübingen, Environmental Toxicology, Center for Applied Geosciences, 72074 Tübingen, Germany.
Baumer A; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. , Leipzig University, Eilenburger Str. 15a, 04317 Leipzig, Germany.
Bittermann K; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Henneberger L; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
König M; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Kühnert C; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
Klüver N; Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, DE-04318 Leipzig, Germany. .
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Źródło :
Environmental science. Processes & impacts [Environ Sci Process Impacts] 2017 Mar 22; Vol. 19 (3), pp. 414-428.
Typ publikacji :
Journal Article
MeSH Terms :
Quantitative Structure-Activity Relationship*
Aliivibrio fischeri/*drug effects
Organic Chemicals/*toxicity
Water Pollutants, Chemical/*toxicity
Biological Assay/methods ; Hazardous Substances/chemistry ; Hazardous Substances/toxicity ; Hydrophobic and Hydrophilic Interactions ; Luminescent Measurements ; Models, Theoretical ; Organic Chemicals/chemistry ; Solubility ; Water ; Water Pollutants, Chemical/chemistry
Czasopismo naukowe
Tytuł :
Modeling Exposure in the Tox21 in Vitro Bioassays.
Autorzy :
Fischer FC; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Henneberger L; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
König M; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Bittermann K; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Linden L; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Goss KU; Department Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
Escher BI; Department Cell Toxicology, Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15, 04318 Leipzig, Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2017 May 15; Vol. 30 (5), pp. 1197-1208. Date of Electronic Publication: 2017 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
Environmental Exposure*
Models, Theoretical*
Toxicity Tests*
Genes, Reporter ; HEK293 Cells ; Hep G2 Cells ; High-Throughput Screening Assays ; Humans ; In Vitro Techniques ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Equilibrium biopartitioning of organic anions - A case study for humans and fish.
Autorzy :
Goss KU; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany; University of Halle-Wittenberg, Institute of Chemistry, Kurt-Mothes-Str. 2, D-06120 Halle, Germany. Electronic address: .
Bittermann K; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany.
Henneberger L; Helmholtz Centre for Environmental Research UFZ, Department of Cell Toxicology, Permoserstr. 15, D-04318 Leipzig, Germany.
Linden L; Helmholtz Centre for Environmental Research UFZ, Department of Analytical Environmental Chemistry, Permoserstr. 15, D-04318 Leipzig, Germany.
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Źródło :
Chemosphere [Chemosphere] 2018 May; Vol. 199, pp. 174-181. Date of Electronic Publication: 2018 Feb 06.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Biological*
Albumins/*metabolism
Fishes/*metabolism
Organic Chemicals/*metabolism
Water Pollutants, Chemical/*metabolism
Absorption, Physiological ; Animals ; Anions ; Humans ; Hydrogen-Ion Concentration ; Membrane Lipids/metabolism ; Organ Specificity ; Organic Chemicals/toxicity ; Species Specificity ; Toxicokinetics ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Cellular Uptake Kinetics of Neutral and Charged Chemicals in in Vitro Assays Measured by Fluorescence Microscopy.
Autorzy :
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Abele C; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Droge STJ; Institute for Biodiversity and Ecosystem Dynamics , University of Amsterdam , Science Park 904 , 1098 XH Amsterdam , Netherlands.
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
König M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Scholz S; Department of Bioanalytical Ecotoxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2018 Aug 20; Vol. 31 (8), pp. 646-657. Date of Electronic Publication: 2018 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hazardous Substances/*pharmacokinetics
Microscopy, Fluorescence/*methods
Animals ; Area Under Curve ; Cell Line ; Cell Line, Tumor ; Culture Media ; Genes, Reporter ; Humans ; In Vitro Techniques ; Thermodynamics
Czasopismo naukowe
Tytuł :
Application of Experimental Polystyrene Partition Constants and Diffusion Coefficients to Predict the Sorption of Neutral Organic Chemicals to Multiwell Plates in in Vivo and in Vitro Bioassays.
Autorzy :
Fischer FC; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Cirpka OA; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
Goss KU; Helmholtz Centre for Environmental Research - UFZ , Department Analytical Environmental Chemistry , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Department Cell Toxicology , Permoserstraße 15 , 04318 Leipzig , Germany.; Eberhard Karls University Tübingen , Center for Applied Geoscience , 72074 Tübingen , Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2018 Nov 20; Vol. 52 (22), pp. 13511-13522. Date of Electronic Publication: 2018 Oct 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organic Chemicals*
Polystyrenes*
Animals ; Biological Assay ; Kinetics ; Plastics
Czasopismo naukowe
Tytuł :
Setting the baseline in in vitro bioassays
Autorzy :
Rscher, B.
Fischer, F. C.
Glauch, L.
Henneberger, L.
Koenig, M.
Mayer, Philipp
Schlichting, R.
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Źródło :
Rscher, B, Fischer, F C, Glauch, L, Henneberger, L, Koenig, M, Mayer, P & Schlichting, R 2019, Setting the baseline in in vitro bioassays . in SETAC Europe 29th Annual Meeting - Abstract Book ., 75, Society of Environmental Toxicology and Chemistry, pp. 18-18, SETAC Europe 29th annual meeting, Helsinki, Finland, 26/05/2019 .
Opis pliku :
application/pdf
Tytuł :
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Autorzy :
Henneberger L; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Fischer FC; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.
Escher BI; Department of Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstr. 15 , 04318 Leipzig , Germany.; Environmental Toxicology, Center for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2019 Jan 22; Vol. 32 (1), pp. 168-178. Date of Electronic Publication: 2019 Jan 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Solid Phase Microextraction*
Phospholipids/*chemistry
Serum Albumin, Bovine/*chemistry
2,4-Dichlorophenoxyacetic Acid/analysis ; Animals ; Cattle ; Cells, Cultured ; Diclofenac/analysis ; Genistein/analysis ; HEK293 Cells ; Humans ; Ibuprofen/analysis ; Kinetics ; Liposomes/chemistry ; Naproxen/analysis ; Torsemide/analysis ; Warfarin/analysis
Czasopismo naukowe
Tytuł :
Combined Ion-Trapping and Mass Balance Models To Describe the pH-Dependent Uptake and Toxicity of Acidic and Basic Pharmaceuticals in Zebrafish Embryos ( Danio rerio).
Autorzy :
Bittner L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Klüver N; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Henneberger L; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Mühlenbrink M; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.
Zarfl C; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
Escher BI; Helmholtz Centre for Environmental Research - UFZ , Permoserstrasse 15 , 04318 Leipzig , Germany.; Eberhard Karls University of Tübingen , Center for Applied Geoscience , Hölderlinstrasse 12 , 72074 Tübingen , Germany.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2019 Jul 02; Vol. 53 (13), pp. 7877-7886. Date of Electronic Publication: 2019 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
Water Pollutants, Chemical*
Zebrafish*
Animals ; Diclofenac ; Embryo, Nonmammalian ; Hydrogen-Ion Concentration
Czasopismo naukowe
Tytuł :
Quantification of freely dissolved effect concentrations in in vitro cell-based bioassays.
Autorzy :
Henneberger L; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany. luise.henneberger@ufz.de.
Mühlenbrink M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
König M; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Schlichting R; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Fischer FC; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.
Escher BI; Department of Cell Toxicology, Helmholtz Centre for Environmental Research (UFZ), Permoserstr. 15, 04318, Leipzig, Germany.; Environmental Toxicology, Center for Applied Geoscience, Eberhard Karls University Tübingen, 72074, Tübingen, Germany.
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Źródło :
Archives of toxicology [Arch Toxicol] 2019 Aug; Vol. 93 (8), pp. 2295-2305. Date of Electronic Publication: 2019 Jun 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay/*methods
Solid Phase Microextraction/*methods
Cell Survival/drug effects ; Hydrogen-Ion Concentration ; Hydrophobic and Hydrophilic Interactions ; In Vitro Techniques ; Oxidative Stress/drug effects ; PPAR gamma/metabolism ; Solubility
Czasopismo naukowe
Tytuł :
How To Improve the Dosing of Chemicals in High-Throughput in Vitro Mammalian Cell Assays.
Autorzy :
Fischer FC; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Henneberger L; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Schlichting R; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.
Escher BI; Department Cell Toxicology , Helmholtz Centre for Environmental Research - UFZ , Permoserstraße 15 , 04318 Leipzig , Germany.; Centre for Applied Geoscience , Eberhard Karls University Tübingen , 72074 Tübingen , Germany.
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Źródło :
Chemical research in toxicology [Chem Res Toxicol] 2019 Aug 19; Vol. 32 (8), pp. 1462-1468. Date of Electronic Publication: 2019 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Assay*
High-Throughput Screening Assays*
Culture Media/*analysis
Animals ; Cell Survival/drug effects ; Culture Media/pharmacology ; Databases, Chemical ; Dose-Response Relationship, Drug ; Humans ; Models, Biological
Czasopismo naukowe

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