Temat: "Hep G2 Cells" - OpacWWW

Skocz do pozycji: 61.

Tytuł:: Ameliorative Effect of Posidonia oceanica on High Glucose-Related Stress in Human Hepatoma HepG2 Cells.
Autorzy:: Vasarri M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.; Department of Chemistry 'Ugo Schiff', University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
Barletta E; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Stio M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Bergonzi MC; Department of Chemistry 'Ugo Schiff', University of Florence, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
Galli A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.
Degl'Innocenti D; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Viale Morgagni 50, 50134 Florence, Italy.; Interuniversity Center of Marine Biology and Applied Ecology 'G. Bacci' (CIBM), Viale N. Sauro 4, 57128 Livorno, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 08; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/drug therapy
Liver Neoplasms*/pathology
Alismatales*
Humans ; Hep G2 Cells ; Matrix Metalloproteinase 2 ; NF-kappa B ; Glucose ; Lipids

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Skocz do pozycji: 62.

Tytuł:: Wild Artichoke ( Cynara cardunculus subsp. sylvestris, Asteraceae) Leaf Extract: Phenolic Profile and Oxidative Stress Inhibitory Effects on HepG2 Cells.
Autorzy:: Acquaviva R; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Research Centre on Nutraceuticals and Health Products (CERNUT), University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; PLANTA/Autonomous Center for Research, Documentation and Training, Via Serraglio Vecchio 28, 90123 Palermo, Italy.
Malfa GA; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Research Centre on Nutraceuticals and Health Products (CERNUT), University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; PLANTA/Autonomous Center for Research, Documentation and Training, Via Serraglio Vecchio 28, 90123 Palermo, Italy.
Santangelo R; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Bianchi S; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Research Centre on Nutraceuticals and Health Products (CERNUT), University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Pappalardo F; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Taviano MF; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Miceli N; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Di Giacomo C; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Research Centre on Nutraceuticals and Health Products (CERNUT), University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Tomasello B; Department of Drug and Health Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Research Centre on Nutraceuticals and Health Products (CERNUT), University of Catania, Viale A. Doria 6, 95125 Catania, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 08; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:: Journal Article
MeSH Terms:: Cynara*/chemistry
Cynara scolymus*/chemistry
Asteraceae*/metabolism
Humans ; Antioxidants/chemistry ; Hep G2 Cells ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Phenols/chemistry ; Oxidative Stress ; Sicily ; RNA, Messenger/metabolism ; Plant Leaves/chemistry

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Skocz do pozycji: 63.

Tytuł:: Exercise activates Sirt1-mediated Drp1 acetylation and inhibits hepatocyte apoptosis to improve nonalcoholic fatty liver disease.
Autorzy:: Hu Z; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Zhang H; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Wang Y; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Li B; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Liu K; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Ran J; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China. .
Li L; First People's Hospital of Kunming City, The Calmette Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2023 Mar 07; Vol. 22 (1), pp. 33. Date of Electronic Publication: 2023 Mar 07.
Typ publikacji:: Journal Article
MeSH Terms:: Dynamins*/genetics
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/therapy
Sirtuin 1*/genetics
Animals ; Humans ; Rats ; Acetylation ; Apoptosis ; Hep G2 Cells ; Oleic Acid ; Physical Conditioning, Animal ; Hepatocytes

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Skocz do pozycji: 64.

Tytuł:: SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells.
Autorzy:: Gao T; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Yang X; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Fujisawa M; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Ohara T; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Wang T; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Tomonobu N; Department of Cell Biology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Sakaguchi M; Department of Cell Biology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Yoshimura T; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
Matsukawa A; Department of Pathology and Experimental Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 05; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 05.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/metabolism
Humans ; Epithelial-Mesenchymal Transition/genetics ; Cell Line, Tumor ; Hep G2 Cells ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic ; Repressor Proteins/genetics

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Skocz do pozycji: 65.

Tytuł:: Differential Lipid Accumulation on HepG2 Cells Triggered by Palmitic and Linoleic Fatty Acids Exposure.
Autorzy:: Teixeira FS; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Pimentel LL; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Vidigal SSMP; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Azevedo-Silva J; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Pintado ME; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.
Rodríguez-Alcalá LM; CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 04; Vol. 28 (5). Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Fatty Acids*/metabolism
Linoleic Acids*/metabolism
Humans ; Hep G2 Cells ; Reactive Oxygen Species/metabolism ; Hepatocytes ; Lipid Metabolism ; Triglycerides/metabolism ; Cholesterol/metabolism ; Linoleic Acid/pharmacology ; Palmitic Acid/pharmacology

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Skocz do pozycji: 66.

Tytuł:: Comparative evaluation of the effects of bisphenol derivatives on oxidative stress parameters in HepG2 cells.
Autorzy:: Ozyurt B; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, Ankara, Turkey.
Ozkemahli G; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Erzincan Binali Yıldırım University, Erzincan, Turkey.
Yirun A; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, Ankara, Turkey.; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Çukurova University, Adana, Turkey.
Ozyurt AB; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, Ankara, Turkey.
Bacanli M; Gülhane Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Health Sciences University, Ankara, Turkey.
Basaran N; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, Ankara, Turkey.
Kocer-Gumusel B; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Lokman Hekim University, Ankara, Turkey.
Erkekoglu P; Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Hacettepe University, Ankara, Turkey.; Pokaż więcej
Źródło:: Drug and chemical toxicology [Drug Chem Toxicol] 2023 Mar; Vol. 46 (2), pp. 314-322. Date of Electronic Publication: 2022 Jan 19.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Antioxidants*/pharmacology
Oxidative Stress*
Child ; Humans ; Hep G2 Cells ; Oxidants ; Reactive Oxygen Species

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Skocz do pozycji: 67.

Tytuł:: Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation.
Autorzy:: Mendenhall MA; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Hong X; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
Hu J; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Feb 28; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:: Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:: Hepatitis B virus*/genetics
Hepatitis B virus*/metabolism
Hepatitis B*
Animals ; Humans ; Capsid/metabolism ; DNA, Circular/genetics ; DNA, Circular/metabolism ; DNA, Viral/genetics ; DNA, Viral/metabolism ; Virus Replication/genetics ; Hep G2 Cells ; Capsid Proteins/genetics ; RNA, Viral/metabolism

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Skocz do pozycji: 68.

Tytuł:: PEGylated Liposomes Loaded with Carbamate Inhibitor ANP0903 Trigger Apoptosis by Enhancing ER Stress in HepG2 Cancer Cells.
Autorzy:: Caddeo C; Department of Scienze della Vita e dell'Ambiente, Sezione di Scienze del Farmaco, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy.
Miglionico R; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Rinaldi R; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Nigro I; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Lamorte D; Laboratory of Preclinical and Translational Research, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), 85028 Rionero in Vulture, Italy.
Chiummiento L; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Lupattelli P; Department of Chimica, Sapienza University of Roma, p.le Aldo Moro 5, 00185 Roma, Italy.
Funicello M; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
D'Orsi R; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Valenti D; Department of Scienze della Vita e dell'Ambiente, Sezione di Scienze del Farmaco, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy.
Santoro V; Department of Farmacia, University of Salerno, Via Giovanni Paolo II 132, 84084 Salerno, Italy.
Fadda AM; Department of Scienze della Vita e dell'Ambiente, Sezione di Scienze del Farmaco, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy.
Bisaccia F; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Vassallo A; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.; Spinoff TNcKILLERS s.r.l., Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Armentano MF; Department of Scienze, University of Basilicata, Viale dell'Ateneo Lucano 10, 85100 Potenza, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 25; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Neoplasms*
Humans ; Liposomes/pharmacology ; Hep G2 Cells ; Carbamates/pharmacology ; Quality of Life ; Apoptosis ; Polyethylene Glycols/pharmacology ; Cell Line, Tumor

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Skocz do pozycji: 69.

Tytuł:: Anti-Cancer Effects of Queen Bee Acid (10-Hydroxy-2-Decenoic Acid) and Its Cellular Mechanisms against Human Hepatoma Cells.
Autorzy:: Saad Al Shehri Z; Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, KSA, Al Dawadmi 1678, Saudi Arabia.
Alanazi AD; Department of Biological Sciences, Faculty of Science and Humanities, Shaqra University, Ad-Dawadimi 11911, Saudi Arabia.
Alnomasy SF; Department of Medical Laboratories Sciences, College of Applied Medical Sciences, Shaqra University, Al-Quwayiyah 19257, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 19; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 19.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Liver Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
MicroRNAs*/therapeutic use
Humans ; bcl-2-Associated X Protein/genetics ; Caspase 3/metabolism ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/genetics ; Hep G2 Cells

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Skocz do pozycji: 70.

Tytuł:: Confusoside from Anneslea fragrans Alleviates Acetaminophen-Induced Liver Injury in HepG2 via PI3K-CASP3 Signaling Pathway.
Autorzy:: Zhao JH; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650500, China.
Li J; Department of Information, The First People's Hospital of Yunnan, Kunming 650021, China.
Zhang XY; The faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Shi S; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650500, China.
Wang L; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650500, China.
Yuan ML; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650500, China.; School of Chemistry and Environment, National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, China.
Liu YP; The faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China.
Wang YD; Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan Minzu University, Kunming 650500, China.; School of Chemistry and Environment, National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 17; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Acetaminophen*/adverse effects
Chemical and Drug Induced Liver Injury*/metabolism
Phytochemicals*/pharmacology
Humans ; Caspase 3/metabolism ; Inflammation/metabolism ; Liver ; Molecular Docking Simulation ; Oxidative Stress ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Hep G2 Cells

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Skocz do pozycji: 71.

Tytuł:: Impact of Deoxynivalenol and Zearalenone as Single and Combined Treatment on DNA, Cell Cycle and Cell Proliferation in HepG2 Cells.
Autorzy:: Domijan AM; Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia.
Hercog K; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 1000 Ljubljana, Slovenia.
Štampar M; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 1000 Ljubljana, Slovenia.
Gajski G; Mutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Gerić M; Mutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
Sokolović M; Poultry Center, Croatian Veterinary Institute, 10000 Zagreb, Croatia.
Žegura B; Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 1000 Ljubljana, Slovenia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Zearalenone*/toxicity
Mycotoxins*/pharmacology
Humans ; Hep G2 Cells ; Cell Cycle ; Cell Proliferation ; DNA/pharmacology

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Skocz do pozycji: 72.

Tytuł:: Berberine Ameliorates Metabolic-Associated Fatty Liver Disease Mediated Metabolism Disorder and Redox Homeostasis by Upregulating Clock Genes: Clock and Bmal1 Expressions.
Autorzy:: Ye C; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Zhang Y; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Lin S; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Chen Y; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Wang Z; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Feng H; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Fang G; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Quan S; School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 16; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Berberine*/metabolism
Metabolic Diseases*/metabolism
Non-alcoholic Fatty Liver Disease*/metabolism
Animals ; Mice ; ARNTL Transcription Factors/genetics ; Glucosamine ; Homeostasis ; Hydrogen Peroxide/metabolism ; Inflammation/metabolism ; Liver/metabolism ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Humans ; Hep G2 Cells

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Skocz do pozycji: 73.

Tytuł:: Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.
Autorzy:: Yuan Y; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Zhu Y; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Li Y; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Li X; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Jiao R; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Bai W; Department of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 07; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:: Journal Article
MeSH Terms:: Proprotein Convertase 9*/genetics
Anthocyanins*
Humans ; Hep G2 Cells ; Cholesterol/metabolism ; Receptors, LDL/metabolism

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Skocz do pozycji: 74.

Tytuł:: Preliminary Structural Characterization of Selenium Nanoparticle Composites Modified by Astragalus Polysaccharide and the Cytotoxicity Mechanism on Liver Cancer Cells.
Autorzy:: Ji H; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Lou X; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Jiao J; College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Li Y; Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China.
Dai K; College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Jia X; Tianjin Key Laboratory of Postharvest Physiology and Storage of Agricultural Products, Key Laboratory of Storage of Agricultural Products, National Engineering Technology Research Center for Preservation of Agricultural Products, Ministry of Agriculture and Rural Affairs, Tianjin 300384, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 06; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: Liver Neoplasms*
Nanoparticles*/chemistry
Selenium*/chemistry
Humans ; Polysaccharides ; Hep G2 Cells

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Skocz do pozycji: 75.

Tytuł:: A Picrocrocin-Enriched Fraction from a Saffron Extract Affects Lipid Homeostasis in HepG2 Cells through a Non-Statin-like Mode.
Autorzy:: Frattaruolo L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Marra F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Lauria G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Siciliano C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Curcio R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Muto L; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Brindisi M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Aiello D; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Arcavacata di Rende, Italy.
Napoli A; Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Arcavacata di Rende, Italy.
Fiermonte G; Department of Biosciences, Biotechnologies and Environment, University of Bari, 70125 Bari, Italy.
Cappello AR; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Fiorillo M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Ahmed A; Department of Biosciences, Biotechnologies and Environment, University of Bari, 70125 Bari, Italy.
Dolce V; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 04; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 04.
Typ publikacji:: Journal Article
MeSH Terms:: Crocus*/chemistry
Humans ; Hep G2 Cells ; Plant Extracts/pharmacology ; Terpenes/pharmacology ; Cyclohexenes/pharmacology

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Skocz do pozycji: 76.

Tytuł:: Effect of Isoquercitrin on Free Fatty Acid-Induced Lipid Accumulation in HepG2 Cells.
Autorzy:: Kim SH; Department of Pharmacy, College of Pharmacy, Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Yun C; Department of Pharmacy, College of Pharmacy, Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.
Kwon D; College of Pharmacy, Jeju Research Institute of Pharmaceutical Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Lee YH; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Republic of Korea.
Kwak JH; College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Jung YS; Department of Pharmacy, College of Pharmacy, Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 03; Vol. 28 (3). Date of Electronic Publication: 2023 Feb 03.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/metabolism
Humans ; Hep G2 Cells ; Fatty Acids, Nonesterified/metabolism ; AMP-Activated Protein Kinases/metabolism ; Liver ; Lipid Metabolism

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Skocz do pozycji: 77.

Tytuł:: Fish oil and chicoric acid combination protects better against palmitate-induced lipid accumulation via regulating AMPK-mediated SREBP-1/FAS and PPARα/UCP2 pathways.
Autorzy:: Mohammadi M; Department of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Abbasalipourkabir R; Department of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Ziamajidi N; Department of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Molecular Medicine Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.; Pokaż więcej
Źródło:: Archives of physiology and biochemistry [Arch Physiol Biochem] 2023 Feb; Vol. 129 (1), pp. 1-9. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/prevention & control
Humans ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; PPAR alpha/genetics ; PPAR alpha/metabolism ; Palmitates ; Fish Oils/pharmacology ; Hep G2 Cells ; Lipid Metabolism ; Uncoupling Protein 2/genetics ; Uncoupling Protein 2/metabolism

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Skocz do pozycji: 78.

Tytuł:: Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius , Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis.
Autorzy:: Dai X; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Sun F; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Deng K; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; Department of Chemistry, Tsinghua University, Beijing 100084, China.
Lin G; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; Department of Chemistry, Tsinghua University, Beijing 100084, China.
Yin W; Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou 510632, China.
Chen H; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Yang D; Division of Gastroenterology and Hepatology, The University of Hongkong-Shenzhen Hospital, Shenzhen 518055, China.
Liu K; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.
Zhang Y; Guangdong Clinical Translational Center for Targeted Drug, Department of Pharmacology, School of Medicine, Jinan University, Guangzhou 510632, China.
Huang L; Precision Medicine and Healthcare Research Center, Center for Biotechnology and Biomedicine, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, State Key Laboratory of Health Sciences and Technology, Tsinghua-Berkeley Shenzhen Institute (TBSI), Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; School of Life Sciences, Tsinghua University, Beijing 100084, China.; Department of Chemistry, Tsinghua University, Beijing 100084, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 17; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Autophagic Cell Death*/drug effects
Carcinoma, Hepatocellular*/metabolism
Croton*/chemistry
Diterpenes, Clerodane*/pharmacology
Liver Neoplasms*/drug therapy
Liver Neoplasms*/metabolism
Humans ; Cell Proliferation/drug effects ; Hep G2 Cells/drug effects ; Hep G2 Cells/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Pyroptosis/drug effects ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 79.

Tytuł:: Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line.
Autorzy:: Pipitone RM; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Zito R; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Lupo G; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Javed A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
La Mantia C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Di Maria G; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Pratelli G; Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.
Di Salvo F; Department of Agricultural, Food and Forest Sciences, University of Palermo, 90128 Palermo, Italy.
Fontana S; Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.
Pucci M; Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.
Carlisi D; Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.
Grimaudo S; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jan 27; Vol. 28 (3). Date of Electronic Publication: 2023 Jan 27.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*/therapeutic use
Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/prevention & control
Non-alcoholic Fatty Liver Disease*/genetics
Humans ; Hep G2 Cells ; Reactive Oxygen Species/metabolism ; Triglycerides/metabolism ; Liver

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Skocz do pozycji: 80.

Tytuł:: Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes.
Autorzy:: Hozumi K; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Sugawara K; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Ishihara T; Department of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan.
Ishihara N; Department of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan.
Ogawa W; Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jan 13; Vol. 13 (1), pp. 746. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: AMP-Activated Protein Kinases*/metabolism
Metformin*/pharmacology
Metformin*/metabolism
Animals ; Mice ; Gene Expression ; Hepatocytes/metabolism ; Hypoglycemic Agents/pharmacology ; Mitochondria/metabolism ; Hep G2 Cells ; Humans

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