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Wyszukujesz frazę ""Heparin"" wg kryterium: Temat


Tytuł :
Safety of High-Dose Unfractionated Heparin for Prophylaxis of Venous Thromboembolism in Hospitalized Obese Patients.
Autorzy :
Regis T; Montefiore Medical Center, Bronx, NY, USA.
Goriacko P; Montefiore Medical Center, Bronx, NY, USA.; Albert Einstein College of Medicine, Bronx, NY, USA.
Ferguson N; Montefiore Medical Center, Bronx, NY, USA.; Albert Einstein College of Medicine, Bronx, NY, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Aug; Vol. 55 (8), pp. 963-969. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Heparin*/adverse effects
Venous Thromboembolism*/epidemiology
Venous Thromboembolism*/prevention & control
Anticoagulants/adverse effects ; Heparin, Low-Molecular-Weight ; Humans ; Obesity/complications ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Transdermal delivery of heparin using low-frequency sonophoresis in combination with sponge spicules for venous thrombosis treatment.
Autorzy :
Zhai H; Department of Marine Biological Science & Technology, College of Ocean & Earth Sciences, Xiamen University, Xiamen 361102, China. .
Zhang C; Department of Marine Biological Science & Technology, College of Ocean & Earth Sciences, Xiamen University, Xiamen 361102, China. .
Ou H; Department of Marine Biological Science & Technology, College of Ocean & Earth Sciences, Xiamen University, Xiamen 361102, China. .
Chen M; Department of Marine Biological Science & Technology, College of Ocean & Earth Sciences, Xiamen University, Xiamen 361102, China. and State-Province Joint Engineering Laboratory of Marine Bioproducts and Technology, Xiamen University, Xiamen 361102, China and Shenzhen Research Institute of Xiamen University, Shenzhen 518000, China.
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Źródło :
Biomaterials science [Biomater Sci] 2021 Aug 21; Vol. 9 (16), pp. 5612-5625. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
Heparin*/metabolism
Venous Thrombosis*/drug therapy
Venous Thrombosis*/metabolism
Administration, Cutaneous ; Animals ; Guinea Pigs ; Heparin, Low-Molecular-Weight ; Rabbits ; Skin/metabolism ; Skin Absorption
Czasopismo naukowe
Tytuł :
APTT therapeutic range for monitoring unfractionated heparin therapy. Significant impact of the anti-Xa reagent used for correlation: Response from original authors Toulon et al.
Autorzy :
Toulon P; Hematology Department, Université Côte d'Azur, CHU Nice, Nice, France.
Smahi M; Hematology Department, Simone Veil Hospital, Eaubonne, France.
De Pooter N; Hematology Department, Centre Hospitalier, Grasse, France.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Aug; Vol. 19 (8), pp. 2090-2091.
Typ publikacji :
Letter; Comment
MeSH Terms :
Anticoagulants*/adverse effects
Heparin*/adverse effects
Heparin, Low-Molecular-Weight ; Humans ; Indicators and Reagents
Opinia redakcyjna
Tytuł :
APTT therapeutic range for monitoring unfractionated heparin therapy. Significant impact of the anti-Xa reagent used for correlation: COMMENT.
Autorzy :
Kovacs MJ; Department of Medicine, Western University, London, ON, Canada.
Lazo-Langner A; Department of Medicine, Western University, London, ON, Canada.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Aug; Vol. 19 (8), pp. 2089.
Typ publikacji :
Letter; Comment
MeSH Terms :
Anticoagulants*/adverse effects
Heparin*/adverse effects
Heparin, Low-Molecular-Weight ; Humans ; Indicators and Reagents
Opinia redakcyjna
Tytuł :
Heparins have adequate ex vivo anticoagulant effects in hospitalized patients with cirrhosis.
Autorzy :
van den Boom BP; Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
von Meijenfeldt FA; Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Adelmeijer J; Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Roberts LN; King's Thrombosis Centre, Department of Haematological Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Bernal W; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Lisman T; Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Jun; Vol. 19 (6), pp. 1472-1482. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Heparin*/therapeutic use
Venous Thromboembolism*/diagnosis
Venous Thromboembolism*/drug therapy
Anticoagulants/therapeutic use ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/drug therapy
Czasopismo naukowe
Tytuł :
Weight-adjusted versus fixed dose heparin thromboprophylaxis in hospitalized obese patients: A systematic review and meta-analysis.
Autorzy :
Ceccato D; Department of Internal Medicine, University of Padua, Padua, Italy. Electronic address: .
Di Vincenzo A; Camposampiero Hospital, Camposampiero, Italy.
Pagano C; Department of Internal Medicine, University of Padua, Padua, Italy.
Pesavento R; Department of Internal Medicine, University of Padua, Padua, Italy.
Prandoni P; Arianna Foundation on Anticoagulation Bologna, Padua, Italy.
Vettor R; Department of Internal Medicine, University of Padua, Padua, Italy.
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Źródło :
European journal of internal medicine [Eur J Intern Med] 2021 Jun; Vol. 88, pp. 73-80. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Heparin*/adverse effects
Venous Thromboembolism*/drug therapy
Venous Thromboembolism*/prevention & control
Anticoagulants/adverse effects ; Heparin, Low-Molecular-Weight ; Humans ; Obesity/complications ; Prospective Studies ; Retrospective Studies
Czasopismo naukowe
Tytuł :
An international survey of low molecular weight heparin prescribing in the context of antenatal venous thromboembolism.
Autorzy :
McFarlane SQ; Institute of Pharmaceutical Science, King's College London, United Kingdom of Great Britain and Northern Ireland.
Patel JP; Institute of Pharmaceutical Science, King's College London, United Kingdom of Great Britain and Northern Ireland; King's Thrombosis Centre, Department of Haematological Medicine, King's College Hospital Foundation NHS Trust, United Kingdom of Great Britain and Northern Ireland. Electronic address: .
Auyeung V; Institute of Pharmaceutical Science, King's College London, United Kingdom of Great Britain and Northern Ireland.
Arya R; King's Thrombosis Centre, Department of Haematological Medicine, King's College Hospital Foundation NHS Trust, United Kingdom of Great Britain and Northern Ireland.
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Źródło :
Thrombosis research [Thromb Res] 2021 Apr; Vol. 200, pp. 99-101. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Letter
MeSH Terms :
Heparin, Low-Molecular-Weight*/therapeutic use
Venous Thromboembolism*/drug therapy
Anticoagulants/therapeutic use ; Female ; Heparin ; Humans ; Pregnancy
Opinia redakcyjna
Tytuł :
Postoperative management of antithrombotic medication in microvascular head and neck reconstruction: a comparative analysis of unfractionated and low-molecular-weight heparin.
Autorzy :
Sievert M; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany. .
Goncalves M; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Tamse R; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Mueller SK; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Koch M; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Gostian AO; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Iro H; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
Scherl C; Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich Alexander University of Erlangen-Nuremberg, Waldstrasse 1, 91054, Erlangen, Germany.
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Źródło :
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2021 May; Vol. 278 (5), pp. 1567-1575. Date of Electronic Publication: 2020 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Fibrinolytic Agents*/therapeutic use
Heparin, Low-Molecular-Weight*/therapeutic use
Anticoagulants/therapeutic use ; Heparin ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Impact of proactive low-molecular weight heparin therapy on outcomes in COVID-1.
Autorzy :
Gormez S
Gumusel HK
Ekicibasi E
Degirmencioglu A
Paudel A
Akan G
Atalar F
Erdim R
Eroglu E
Dagdelen S
Sariguzel N
Kirisoglu CE
Pamukcu B
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Źródło :
Bratislavske lekarske listy [Bratisl Lek Listy] 2021; Vol. 122 (8), pp. 582-589.
Typ publikacji :
Journal Article; Multicenter Study; Observational Study
MeSH Terms :
COVID-19*
Heparin, Low-Molecular-Weight*
Anticoagulants ; Heparin ; Humans ; Molecular Weight ; Retrospective Studies ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
A new strategy for an improved detection of residual heparin and excess protamine - A first in-vitro approach.
Autorzy :
Groene P; Department of Anaesthesiology, University Hospital, LMU Munich, Germany. Electronic address: .
da Silva Gaspar Jung S; Department of Anaesthesiology, University Hospital, LMU Munich, Germany.
Acevedo AC; Department of Anaesthesiology, University Hospital, LMU Munich, Germany.
Lenhart B; Department of Anaesthesiology, University Hospital, LMU Munich, Germany.
Schäfer ST; Department of Anaesthesiology, University Hospital, LMU Munich, Germany.
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Źródło :
Thrombosis research [Thromb Res] 2021 Mar; Vol. 199, pp. 75-78. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Heparin*/adverse effects
Protamines*
Anticoagulants ; Hematologic Tests ; Heparin Antagonists ; Humans
Raport
Tytuł :
Timing and Type of Venous Thromboembolic Prophylaxis in Isolated Severe Liver Injury Managed Non-Operatively.
Autorzy :
Jakob DA; Division of Trauma and Critical Care, Department of Surgery, University of Southern California, 2051 Marengo Street, Inpatient Tower (C), 5th Floor, C5L100, Los Angeles, CA, 90033, USA.
Benjamin ER; Division of Trauma and Critical Care, Department of Surgery, University of Southern California, 2051 Marengo Street, Inpatient Tower (C), 5th Floor, C5L100, Los Angeles, CA, 90033, USA. .
Liasidis P; Division of Trauma and Critical Care, Department of Surgery, University of Southern California, 2051 Marengo Street, Inpatient Tower (C), 5th Floor, C5L100, Los Angeles, CA, 90033, USA.
Demetriades D; Division of Trauma and Critical Care, Department of Surgery, University of Southern California, 2051 Marengo Street, Inpatient Tower (C), 5th Floor, C5L100, Los Angeles, CA, 90033, USA.
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Źródło :
World journal of surgery [World J Surg] 2021 Mar; Vol. 45 (3), pp. 746-753. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
MeSH Terms :
Heparin, Low-Molecular-Weight*/therapeutic use
Venous Thromboembolism*/etiology
Venous Thromboembolism*/prevention & control
Heparin ; Humans ; Liver ; Retrospective Studies
Czasopismo naukowe
Tytuł :
COVID-19 Related Coagulopathy: What is Known Up to Now.
Autorzy :
Pena ALB; Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Oliveira RA; Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Severo RG; Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Simões E Silva AC; Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Minas Gerais, Brazil.
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Źródło :
Current medicinal chemistry [Curr Med Chem] 2021; Vol. 28 (21), pp. 4207-4225.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19*
Heparin, Low-Molecular-Weight*
Aftercare ; Female ; Heparin ; Humans ; Patient Discharge ; Pregnancy ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
[Determination of sulfation degree of heparin and low molecular weight heparins by capillary electrophoresis].
Autorzy :
Shen Y; State Key Lab of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
Kang J; State Key Lab of Bio-Organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
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Źródło :
Se pu = Chinese journal of chromatography [Se Pu] 2020 Oct 08; Vol. 38 (10), pp. 1238-1242.
Typ publikacji :
Journal Article
MeSH Terms :
Heparin*/analysis
Heparin, Low-Molecular-Weight*/analysis
Anticoagulants/analysis ; Electrophoresis, Capillary ; Enoxaparin/analysis ; Heparin Lyase ; Molecular Weight
Czasopismo naukowe
Tytuł :
Low-molecular weight heparin prevents portal vein system thrombosis after splenectomy: a systematic review and meta-analysis.
Autorzy :
Yang M; Department of Hepatobiliary Surgery, Affiliated Hospital of ChengDe Medical University, Chengde, China.
Liu J; Department of Hepatobiliary Surgery, Affiliated Hospital of ChengDe Medical University, Chengde, China.
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Źródło :
ANZ journal of surgery [ANZ J Surg] 2020 Dec; Vol. 90 (12), pp. 2420-2424. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Meta-Analysis; Review; Systematic Review
MeSH Terms :
Heparin, Low-Molecular-Weight*/therapeutic use
Splenectomy*/adverse effects
Anticoagulants/therapeutic use ; Heparin ; Humans ; Molecular Weight ; Portal Vein ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control
Czasopismo naukowe
Tytuł :
A systematic review on the efficacy and safety of low molecular weight heparin as an anticancer therapeutic in preclinical animal models.
Autorzy :
Ripsman D; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada; Faculty of Medicine, University of Ottawa, 451 Smyth Rd #2044, Ottawa, ON K1H 8M5, Canada. Electronic address: .
Fergusson DA; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada; Faculty of Medicine, University of Ottawa, 451 Smyth Rd #2044, Ottawa, ON K1H 8M5, Canada. Electronic address: .
Montroy J; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada. Electronic address: .
Auer RC; Department of Surgery, The Ottawa Hospital, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada; Cancer Therapeutics Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada. Electronic address: .
Huang JW; Faculty of Medicine, University of Ottawa, 451 Smyth Rd #2044, Ottawa, ON K1H 8M5, Canada. Electronic address: .
Dobriyal A; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada; Faculty of Medicine, University of Ottawa, 451 Smyth Rd #2044, Ottawa, ON K1H 8M5, Canada. Electronic address: .
Wesch N; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada.
Carrier M; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada; Faculty of Medicine, University of Ottawa, 451 Smyth Rd #2044, Ottawa, ON K1H 8M5, Canada. Electronic address: .
Lalu MM; Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada; Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Room B307, 1053 Carling Avenue, Mail Stop 249, Ottawa, ON K1Y 4E9, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6, Canada. Electronic address: .
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Źródło :
Thrombosis research [Thromb Res] 2020 Nov; Vol. 195, pp. 103-113. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Heparin, Low-Molecular-Weight*/therapeutic use
Neoplasms*/drug therapy
Animals ; Anticoagulants ; Heparin ; Models, Animal
Czasopismo naukowe
Tytuł :
Hypersensitivity due to unfractionated heparin treatment in a pregnant woman.
Autorzy :
Kajita A; Department of Dermatology, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
Sato E; Department of Dermatology, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
Imafuku S; Department of Dermatology, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
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Źródło :
The Journal of dermatology [J Dermatol] 2020 Nov; Vol. 47 (11), pp. e419-e421. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Letter
MeSH Terms :
Heparin*/adverse effects
Pregnant Women*
Anticoagulants/adverse effects ; Female ; Heparin, Low-Molecular-Weight ; Humans ; Pregnancy
Opinia redakcyjna
Tytuł :
Heparins as cancer therapy: in theory, they should have worked.
Autorzy :
Posch F; Division of Oncology, Department of Internal Medicine, Department of Internal Medicine, Medical University of Graz, Graz, Austria. Electronic address: .
Hatzl S; Division of Haematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Ay C; Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Comprehensive Cancer Centre Vienna, Vienna, Austria.
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Źródło :
The Lancet. Haematology [Lancet Haematol] 2020 Oct; Vol. 7 (10), pp. e703-e704.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Heparin*
Neoplasms*
Heparin, Low-Molecular-Weight ; Humans
Czasopismo naukowe
Tytuł :
Administering DVT Prophylaxis Sooner Than 48 Hours Does Not Increase Failure of Nonoperative Management of High-Grade (Grades III-V) Splenic Injuries.
Autorzy :
Griffard J; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
Sappington B; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
Griffard M; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
Bollig R; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
McMillen J; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
McKinney A; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
Smith L; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
Daley B; 21823 University of Tennessee Medical Center Knoxville, Knoxville, TN, USA.
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Źródło :
The American surgeon [Am Surg] 2021 Apr; Vol. 87 (4), pp. 527-531. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Journal Article
MeSH Terms :
Treatment Failure*
Abdominal Injuries/*therapy
Anticoagulants/*therapeutic use
Heparin/*therapeutic use
Spleen/*injuries
Venous Thrombosis/*prevention & control
Adult ; Chemoprevention ; Female ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Injury Severity Score ; Male ; Prospective Studies ; Time Factors
Czasopismo naukowe
Tytuł :
Andexanet Alfa, the Possible Alternative to Protamine for Reversal of Unfractionated Heparin.
Autorzy :
Maneno JN; College of Pharmacy, Belmont University, Nashville, TN, USA.
Ness GL; College of Pharmacy, Belmont University, Nashville, TN, USA.
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Źródło :
The Annals of pharmacotherapy [Ann Pharmacother] 2021 Feb; Vol. 55 (2), pp. 261-264. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Blood Coagulation/*drug effects
Factor Xa/*therapeutic use
Heparin Antagonists/*therapeutic use
Protamines/*therapeutic use
Recombinant Proteins/*therapeutic use
Anticoagulants/adverse effects ; Blood Coagulation Tests ; Factor Xa/administration & dosage ; Factor Xa/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/prevention & control ; Heparin/adverse effects ; Heparin Antagonists/administration & dosage ; Heparin Antagonists/adverse effects ; Heparin Antagonists/pharmacology ; Humans ; Protamines/administration & dosage ; Protamines/adverse effects ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/adverse effects
Czasopismo naukowe
Tytuł :
Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Autorzy :
Tree JA; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
Turnbull JE; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK.; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Buttigieg KR; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
Elmore MJ; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
Coombes N; National Infection Service, Public Health England, Porton Down, Salisbury, UK.
Hogwood J; Haemostasis Section, Biotherapeutics, National Institute for Biological Standards and Control (NIBSC), Potters Bar, UK.
Mycroft-West CJ; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
Lima MA; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
Skidmore MA; Molecular & Structural Biosciences, School of Life Sciences, Keele University, Newcastle-Under-Lyme, UK.
Karlsson R; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Chen YH; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Yang Z; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
Spalluto CM; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
Staples KJ; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
Yates EA; Department of Biochemistry and Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, UK.
Gray E; Haemostasis Section, Biotherapeutics, National Institute for Biological Standards and Control (NIBSC), Potters Bar, UK.; Sackler Institute of Pulmonary Pharmacology, King's College London, London, UK.
Singh D; Medicines Evaluation Unit, University of Manchester, Manchester University Hospital NHS Foundation Trust, Manchester, UK.
Wilkinson T; Department of Respiratory Medicine, University of Southampton, Southampton, UK.
Page CP; Sackler Institute of Pulmonary Pharmacology, King's College London, London, UK.
Carroll MW; National Infection Service, Public Health England, Porton Down, Salisbury, UK.; Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, Oxford University, Oxford, UK.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2021 Feb; Vol. 178 (3), pp. 626-635. Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heparin/*pharmacology
SARS-CoV-2/*growth & development
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antiviral Agents/pharmacology ; COVID-19/drug therapy ; Chlorocebus aethiops ; Heparin/metabolism ; Heparin/therapeutic use ; Heparin, Low-Molecular-Weight/pharmacology ; Protein Binding/drug effects ; Spike Glycoprotein, Coronavirus/metabolism ; Viral Plaque Assay
Czasopismo naukowe

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