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Wyszukujesz frazę ""Heparitin Sulfate"" wg kryterium: Temat


Tytuł :
Heparan sulfate controls skeletal muscle differentiation and motor functions.
Autorzy :
Yokoyama M; Department of Pharmacology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Matsuzawa T; Department of Pharmacology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Yoshikawa T; Department of Pharmacology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan. Electronic address: .
Nunomiya A; Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
Yamaguchi Y; Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, USA.
Yanai K; Department of Pharmacology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2020 Dec; Vol. 1864 (12), pp. 129707. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle Development*
Heparitin Sulfate/*metabolism
Muscle, Skeletal/*physiology
Myoblasts/*cytology
Animals ; CRISPR-Cas Systems ; Cell Differentiation ; Cell Line ; Heparitin Sulfate/antagonists & inhibitors ; Heparitin Sulfate/genetics ; Mice ; Motor Activity ; Muscle, Skeletal/cytology ; Myoblasts/metabolism
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2.
Autorzy :
Clausen TM; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Department of Infectious Disease, Copenhagen University Hospital, 2200 Copenhagen, Denmark. Electronic address: .
Sandoval DR; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Spliid CB; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Department of Infectious Disease, Copenhagen University Hospital, 2200 Copenhagen, Denmark.
Pihl J; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Department of Infectious Disease, Copenhagen University Hospital, 2200 Copenhagen, Denmark.
Perrett HR; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Painter CD; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA.
Narayanan A; Department of Biochemistry and Molecular Biology, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.
Majowicz SA; Department of Biochemistry and Molecular Biology, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.
Kwong EM; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
McVicar RN; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Thacker BE; TEGA Therapeutics, Inc., 3550 General Atomics Court, G02-102, San Diego, CA 92121, USA.
Glass CA; TEGA Therapeutics, Inc., 3550 General Atomics Court, G02-102, San Diego, CA 92121, USA.
Yang Z; Copenhagen Center for Glycomics, Department of Molecular and Cellular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.
Torres JL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Golden GJ; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA.
Bartels PL; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093, USA.
Porell RN; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Garretson AF; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Laubach L; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Feldman J; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Yin X; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
Pu Y; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
Hauser BM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Caradonna TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.
Kellman BP; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, CA 92093, USA; Bioinformatics and Systems Biology Program, University of California, San Diego, La Jolla, CA 92093, USA.
Martino C; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.
Gordts PLSM; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093, USA.
Chanda SK; Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
Schmidt AG; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.
Godula K; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093, USA.
Leibel SL; Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.
Jose J; Department of Biochemistry and Molecular Biology, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA.
Corbett KD; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Carlin AF; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Esko JD; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: .
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Źródło :
Cell [Cell] 2020 Nov 12; Vol. 183 (4), pp. 1043-1057.e15. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus/*physiology
Heparitin Sulfate/*metabolism
Peptidyl-Dipeptidase A/*metabolism
Spike Glycoprotein, Coronavirus/*metabolism
Amino Acid Sequence ; Angiotensin-Converting Enzyme 2 ; Betacoronavirus/isolation & purification ; Binding Sites ; COVID-19 ; Cell Line ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Heparin/chemistry ; Heparin/metabolism ; Heparitin Sulfate/chemistry ; Humans ; Kidney/metabolism ; Lung/metabolism ; Molecular Dynamics Simulation ; Pandemics ; Peptidyl-Dipeptidase A/chemistry ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; Protein Binding ; Protein Domains ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Virus Internalization
Czasopismo naukowe
Tytuł :
Vascular Endothelial Growth Factor 165-Binding Heparan Sulfate Promotes Functional Recovery From Cerebral Ischemia.
Autorzy :
Chan SJ; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Esposito E; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Hayakawa K; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Department of Neurology (K.H., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Mandaville E; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Smith RAA; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Guo S; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Niu W; Tissue Engineering Laboratories, VA Boston Healthcare System, MA (W.N.).
Wong PT; Department of Pharmacology, National University of Singapore (P.T.H.W).
Cool SM; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
Lo EH; Department of Radiology (S.J.C., E.E., K.H., E.M., S.G., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.; Department of Neurology (K.H., E.H.L.), Massachusetts General Hospital, Harvard Medical School, Charlestown.
Nurcombe V; Institute of Medical Biology, Glycotherapeutics Group, A*STAR (S.J.C., R.A.A.S., S.M.C., V.N.).
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Źródło :
Stroke [Stroke] 2020 Sep; Vol. 51 (9), pp. 2844-2853. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Brain Ischemia/*drug therapy
Heparitin Sulfate/*therapeutic use
Stroke/*drug therapy
Vascular Endothelial Growth Factor A/*therapeutic use
Animals ; Blood-Brain Barrier/drug effects ; Cell Proliferation/drug effects ; Heparitin Sulfate/administration & dosage ; Infarction, Middle Cerebral Artery/prevention & control ; Injections, Intraventricular ; Ischemic Attack, Transient/drug therapy ; Ischemic Attack, Transient/physiopathology ; Male ; Neovascularization, Physiologic/drug effects ; Neural Stem Cells/drug effects ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Vascular Endothelial Growth Factor A/administration & dosage ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
Alveolar heparan sulfate shedding impedes recovery from bleomycin-induced lung injury.
Autorzy :
LaRivière WB; Medical Scientist Training Program, University of Colorado School of Medicine, Aurora, Colorado.; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado.; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Liao S; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
McMurtry SA; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Oshima K; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Han X; Department of Chemistry, Rensselaer Polytechnic Institute, Troy, New York.
Zhang F; Department of Chemistry, Rensselaer Polytechnic Institute, Troy, New York.
Yan S; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.; College of Life Sciences, Henan Normal University, Xinxiang, China.
Haeger SM; Medical Scientist Training Program, University of Colorado School of Medicine, Aurora, Colorado.; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado.; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Ransom M; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Bastarache JA; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Linhardt RJ; Department of Chemistry, Rensselaer Polytechnic Institute, Troy, New York.
Schmidt EP; Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado.; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.; Department of Medicine, Denver Health Medical Center, Denver, Colorado.
Yang Y; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 Jun 01; Vol. 318 (6), pp. L1198-L1210. Date of Electronic Publication: 2020 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Heparitin Sulfate/*metabolism
Lung Injury/*chemically induced
Lung Injury/*metabolism
Pulmonary Alveoli/*metabolism
Pulmonary Alveoli/*pathology
Animals ; Bleomycin ; Cell Line ; Glucuronidase/metabolism ; Heparitin Sulfate/administration & dosage ; Intercellular Signaling Peptides and Proteins/metabolism ; Lung Injury/physiopathology ; Matrix Metalloproteinases/metabolism ; Mice, Inbred C57BL ; Pulmonary Alveoli/physiopathology ; Respiratory Function Tests ; Respiratory Mechanics ; Risk Factors ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis.
Autorzy :
Weiss RJ; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093-0687.
Spahn PN; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093-0760.
Toledo AG; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093-0687.
Chiang AWT; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093-0760.
Kellman BP; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093-0760.
Li J; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093-0687.
Benner C; Department of Medicine, University of California San Diego, La Jolla, CA 92093-0687.
Glass CK; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093-0687.; Department of Medicine, University of California San Diego, La Jolla, CA 92093-0687.
Gordts PLSM; Department of Medicine, University of California San Diego, La Jolla, CA 92093-0687.; Glycobiology Research and Training Center, University of California San Diego, La Jolla, CA 92093-0687.
Lewis NE; Department of Pediatrics, University of California San Diego, La Jolla, CA 92093-0760.; Glycobiology Research and Training Center, University of California San Diego, La Jolla, CA 92093-0687.; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093-0687.
Esko JD; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA 92093-0687; .; Glycobiology Research and Training Center, University of California San Diego, La Jolla, CA 92093-0687.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Apr 28; Vol. 117 (17), pp. 9311-9317. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*metabolism
Heparin/*metabolism
Heparitin Sulfate/*biosynthesis
Animals ; Anticoagulants ; Cell Line ; Cells, Cultured ; Chromatography, High Pressure Liquid ; Gene Expression Regulation/genetics ; HeLa Cells ; Heparin/biosynthesis ; Heparin/genetics ; Heparitin Sulfate/genetics ; Heparitin Sulfate/metabolism ; Humans ; Mast Cells/metabolism ; Sulfotransferases/metabolism ; Swine ; Transcription Factors
Czasopismo naukowe
Tytuł :
Danaparoid is effective and safe for patients with obstetric antiphospholipid syndrome.
Autorzy :
Yoshihara H; Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
Sugiura-Ogasawara M; Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
Kitaori T; Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
Katano K; Obstetrics & Gynecology Katano Clinic, Kasugai, Japan.
Ozaki Y; Department of Obstetrics and Gynecology, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan.
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Źródło :
Modern rheumatology [Mod Rheumatol] 2020 Mar; Vol. 30 (2), pp. 332-337. Date of Electronic Publication: 2019 Apr 24.
Typ publikacji :
Journal Article
MeSH Terms :
Antiphospholipid Syndrome/*drug therapy
Chondroitin Sulfates/*therapeutic use
Dermatan Sulfate/*therapeutic use
Fibrinolytic Agents/*therapeutic use
Heparitin Sulfate/*therapeutic use
Pregnancy Complications/*drug therapy
Adult ; Chondroitin Sulfates/administration & dosage ; Chondroitin Sulfates/adverse effects ; Dermatan Sulfate/administration & dosage ; Dermatan Sulfate/adverse effects ; Female ; Fibrinolytic Agents/administration & dosage ; Fibrinolytic Agents/adverse effects ; Heparitin Sulfate/administration & dosage ; Heparitin Sulfate/adverse effects ; Humans ; Pregnancy ; Pregnancy Outcome
Czasopismo naukowe
Tytuł :
Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides.
Autorzy :
Zhu S; Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
Li J; Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
Loka RS; Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
Song Z; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201, United States.
Vlodavsky I; Cancer and Vascular Biology Research Center, Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel.
Zhang K; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan 48201, United States.
Nguyen HM; Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Apr 23; Vol. 63 (8), pp. 4227-4255. Date of Electronic Publication: 2020 Apr 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme Activation/*physiology
Glucuronidase/*metabolism
Glycosides/*metabolism
Heparitin Sulfate/*metabolism
Oligosaccharides/*metabolism
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Dose-Response Relationship, Drug ; Enzyme Activation/drug effects ; Glycosides/chemical synthesis ; Heparin/pharmacology ; Heparitin Sulfate/antagonists & inhibitors ; Humans ; Mice ; Molecular Docking Simulation/methods ; Oligosaccharides/chemical synthesis
Czasopismo naukowe
Tytuł :
Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates.
Autorzy :
Lindsay SL; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
McCanney GA; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Willison AG; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Barnett SC; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. .
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Źródło :
Nature reviews. Neurology [Nat Rev Neurol] 2020 Apr; Vol. 16 (4), pp. 229-240. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Spinal Cord Regeneration*
Heparitin Sulfate/*therapeutic use
Mesenchymal Stem Cell Transplantation/*methods
Olfactory Mucosa/*cytology
Spinal Cord Injuries/*therapy
Cell Transplantation/methods ; Chondroitin Sulfate Proteoglycans/metabolism ; Heparan Sulfate Proteoglycans/metabolism ; Heparin/therapeutic use ; Heparitin Sulfate/analogs & derivatives ; Humans ; Mesenchymal Stem Cells/cytology ; Nerve Regeneration ; Neuroglia ; Olfactory Mucosa/physiology ; Olfactory Receptor Neurons
Czasopismo naukowe
Tytuł :
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides.
Autorzy :
Miller RL; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, N 2200, Denmark. .; Centre for Glycobiology, Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK. .; Laboratory of Cancer Biology, Department of Oncology, Medical Sciences Division, University of Oxford, Old Road Campus Research Building, Old Road Campus, Roosevelt Drive, Oxford, OX3 7DQ, UK. .
Guimond SE; Centre for Glycobiology, Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK.; Institute for Science and Technology in Medicine, School of Medicine, Keele University, Keele, Staffordshire, ST5 5BG, UK.
Schwörer R; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Road, Gracefield, Lower Hutt, 5010, New Zealand.
Zubkova OV; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Road, Gracefield, Lower Hutt, 5010, New Zealand.
Tyler PC; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Road, Gracefield, Lower Hutt, 5010, New Zealand.
Xu Y; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Liu J; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, 27599, USA.
Chopra P; Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.
Boons GJ; Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, 30602, USA.; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Science, and Bijvoet Center for Biomolecular Research, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
Grabarics M; Freie Universitaet Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195, Berlin, Germany.; Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, 14195, Berlin, Germany.
Manz C; Freie Universitaet Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195, Berlin, Germany.; Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, 14195, Berlin, Germany.
Hofmann J; Freie Universitaet Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195, Berlin, Germany.; Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, 14195, Berlin, Germany.
Karlsson NG; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Turnbull JE; Copenhagen Center for Glycomics, Department of Cellular & Molecular Medicine, University of Copenhagen, Copenhagen, N 2200, Denmark.; Centre for Glycobiology, Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK.
Struwe WB; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3QZ, UK.
Pagel K; Freie Universitaet Berlin, Institute of Chemistry and Biochemistry, Takustrasse 3, 14195, Berlin, Germany.; Fritz Haber Institute of the Max Planck Society, Faradayweg 4-6, 14195, Berlin, Germany.
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Źródło :
Nature communications [Nat Commun] 2020 Mar 20; Vol. 11 (1), pp. 1481. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ions*
Heparitin Sulfate/*chemistry
Mass Spectrometry/*methods
Oligosaccharides/*chemistry
Epitopes ; Fibroblast Growth Factors/metabolism ; Glucuronic Acid/chemistry ; Heparin ; Heparitin Sulfate/metabolism ; Sequence Analysis/methods ; Structure-Activity Relationship ; Sulfotransferases/metabolism
Czasopismo naukowe
Tytuł :
The role of heparin/heparan sulphate in the IFN-γ-led Arena.
Autorzy :
Xu K; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, 266000, Shandong, PR China.
Jin L; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Qingdao, 266000, Shandong, PR China. Electronic address: .
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Źródło :
Biochimie [Biochimie] 2020 Mar; Vol. 170, pp. 1-9. Date of Electronic Publication: 2019 Nov 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heparin/*metabolism
Heparitin Sulfate/*metabolism
Interferon-gamma/*metabolism
Animals ; Binding Sites ; Heparin/chemistry ; Heparitin Sulfate/chemistry ; Humans ; Interferon-gamma/chemistry ; Signal Transduction ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Salt and solvent effects in the microscale chromatographic separation of heparan sulfate disaccharides.
Autorzy :
Tóth G; MS Proteomics Research Group, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2., H-1117 Budapest, Hungary; Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szent Gellért tér 4., H-1111 Budapest, Hungary.
Vékey K; MS Proteomics Research Group, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2., H-1117 Budapest, Hungary.
Drahos L; MS Proteomics Research Group, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2., H-1117 Budapest, Hungary.
Horváth V; Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, Szent Gellért tér 4., H-1111 Budapest, Hungary; MTA-BME Computation Driven Chemistry Research Group, Szent Gellért tér 4., H-1111 Budapest, Hungary.
Turiák L; MS Proteomics Research Group, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2., H-1117 Budapest, Hungary. Electronic address: .
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Źródło :
Journal of chromatography. A [J Chromatogr A] 2020 Jan 11; Vol. 1610, pp. 460548. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, Liquid/*methods
Heparitin Sulfate/*isolation & purification
Sodium Chloride/*chemistry
Animals ; Cattle ; Disaccharides/analysis ; Disaccharides/chemistry ; Disaccharides/isolation & purification ; Formates/chemistry ; Heparitin Sulfate/analysis ; Heparitin Sulfate/chemistry ; Hydrophobic and Hydrophilic Interactions ; Limit of Detection ; Linear Models ; Solvents/chemistry ; Swine
Czasopismo naukowe
Tytuł :
Molecular Aspects of Heparanase Interaction with Heparan Sulfate, Heparin and Glycol Split Heparin.
Autorzy :
Elli S; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Milan, Italy. .
Guerrini M; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Milan, Italy. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1221, pp. 169-188.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Glucuronidase*/antagonists & inhibitors
Glucuronidase*/chemistry
Glucuronidase*/metabolism
Glycols*/chemistry
Glycols*/metabolism
Heparin*/chemistry
Heparin*/metabolism
Heparitin Sulfate*/chemistry
Heparitin Sulfate*/metabolism
Humans ; Hydrolysis ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration in Drosophila parkin Mutants.
Autorzy :
Reynolds-Peterson C; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Xu J; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Zhao N; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Cruse C; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Yonel B; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Trasorras C; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Toyoda H; Faculty of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, JAPAN.
Kinoshita-Toyoda A; Faculty of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, JAPAN.
Dobson J; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Schultheis N; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Jiang M; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and.
Selleck S; Department of Biochemistry & Molecular Biology, The Pennsylvania State University, University Park, PA, 16802 and .
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Źródło :
G3 (Bethesda, Md.) [G3 (Bethesda)] 2020 Jan 07; Vol. 10 (1), pp. 129-141. Date of Electronic Publication: 2020 Jan 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*
Longevity*
Oxidative Stress*
Drosophila Proteins/*genetics
Heparitin Sulfate/*biosynthesis
Ubiquitin-Protein Ligases/*genetics
Animals ; Brain/metabolism ; Compound Eye, Arthropod/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster ; Heparitin Sulfate/genetics ; Muscles/metabolism ; Mutation ; Presenilins/genetics ; Presenilins/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
PI-88 and Related Heparan Sulfate Mimetics.
Autorzy :
Chhabra M; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.
Ferro V; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia. .; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1221, pp. 473-491.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*pharmacology
Heparitin Sulfate/*pharmacology
Neoplasms/*drug therapy
Oligosaccharides/*pharmacology
Animals ; Antineoplastic Agents/therapeutic use ; Glucuronidase/antagonists & inhibitors ; Heparitin Sulfate/chemistry ; Humans ; Neoplasms/blood supply ; Neoplasms/enzymology ; Neovascularization, Pathologic/drug therapy ; Oligosaccharides/chemistry ; Oligosaccharides/therapeutic use ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Comparison of Danaparoid Sodium and Synthetic Protease Inhibitors for the Treatment of Disseminated Intravascular Coagulation Associated with Hematological Malignancies: A Retrospective Analysis.
Autorzy :
Minakata D; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Fujiwara SI; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Hayakawa J; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Nakasone H; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Ikeda T; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Kawaguchi SI; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Toda Y; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ito S; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ochi SI; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Nagayama T; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Mashima K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Umino K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Nakano H; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Yamasaki R; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Morita K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Kawasaki Y; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Sugimoto M; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ishihara Y; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Yamamoto C; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ashizawa M; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Hatano K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Sato K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Oh I; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ohmine K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Muroi K; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Ohmori T; Department of Biochemistry, Jichi Medical University, Tochigi, Japan.
Kanda Y; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan, .; Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan, .
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Źródło :
Acta haematologica [Acta Haematol] 2020; Vol. 143 (3), pp. 250-259. Date of Electronic Publication: 2019 Aug 28.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Chondroitin Sulfates/*therapeutic use
Dermatan Sulfate/*therapeutic use
Hematologic Neoplasms/*blood
Heparitin Sulfate/*therapeutic use
Protease Inhibitors/*therapeutic use
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Blood Component Transfusion ; Chondroitin Sulfates/adverse effects ; Dermatan Sulfate/adverse effects ; Disseminated Intravascular Coagulation/drug therapy ; Disseminated Intravascular Coagulation/therapy ; Female ; Fibrin Fibrinogen Degradation Products/analysis ; Fibrinogen/analysis ; Hematologic Neoplasms/drug therapy ; Hemorrhage/etiology ; Hemorrhage/mortality ; Heparitin Sulfate/adverse effects ; Humans ; Male ; Middle Aged ; Plasma ; Protease Inhibitors/adverse effects ; Prothrombin Time ; Retrospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
The effect of heparan sulfate on promoting amyloid fibril formation by β-casein and their binding research with multi-spectroscopic approaches.
Autorzy :
Wang J; Pharmacy College, Jilin University, Changchun 130021, PR China.
Zhu H; College of Environmental and Resource Sciences, Jilin Agricultural University, Changchun 130118, PR China.
Gan H; China-Japan Union Hospital, Jilin University, Changchun 130021, PR China.
Meng Q; Pharmacy College, Jilin University, Changchun 130021, PR China.
Du G; Pharmacy College, Jilin University, Changchun 130021, PR China.
An Y; Pharmacy College, Jilin University, Changchun 130021, PR China.
Liu J; Pharmacy College, Jilin University, Changchun 130021, PR China. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2020 Jan; Vol. 202, pp. 111671. Date of Electronic Publication: 2019 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid/*metabolism
Caseins/*chemistry
Heparitin Sulfate/*chemistry
Amyloid/chemistry ; Animals ; Binding Sites ; Caseins/metabolism ; Cattle ; Circular Dichroism ; Fluorescence Resonance Energy Transfer ; Heparitin Sulfate/metabolism ; Hydrophobic and Hydrophilic Interactions ; Microscopy, Electron, Transmission ; Protein Binding ; Thermodynamics
Czasopismo naukowe
Tytuł :
Implications of Heparan Sulfate and Heparanase in Amyloid Diseases.
Autorzy :
Li JP; Department of Medical Biochemistry and Microbiology and the SciLifeLab, Uppsala University, Uppsala, Sweden. .
Zhang X; Department of Neuroscience, Uppsala University, Uppsala, Sweden.
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1221, pp. 631-645.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Amyloidosis/*metabolism
Glucuronidase/*metabolism
Heparitin Sulfate/*metabolism
Alzheimer Disease/enzymology ; Alzheimer Disease/metabolism ; Amyloidosis/enzymology ; Animals ; Heparan Sulfate Proteoglycans ; Heparitin Sulfate/chemistry ; Humans
Czasopismo naukowe
Tytuł :
Heparan Sulfate in the Tumor Microenvironment.
Autorzy :
Bartolini B; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Caravà E; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Caon I; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Parnigoni A; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Moretto P; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Passi A; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Vigetti D; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Viola M; Department of Medicine and Surgery, University of Insubria, Varese, Italy. .
Karousou E; Department of Medicine and Surgery, University of Insubria, Varese, Italy. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1245, pp. 147-161.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heparitin Sulfate*/metabolism
Neoplasms*/metabolism
Neoplasms*/pathology
Tumor Microenvironment*
Extracellular Matrix/metabolism ; Heparan Sulfate Proteoglycans/metabolism ; Humans
Czasopismo naukowe
Tytuł :
Bi-allelic Pathogenic Variants in HS2ST1 Cause a Syndrome Characterized by Developmental Delay and Corpus Callosum, Skeletal, and Renal Abnormalities.
Autorzy :
Schneeberger PE; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
von Elsner L; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Barker EL; Nottingham Biodiscovery Institute, University of Nottingham, University Park NG7 2RD, UK.
Meinecke P; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Marquardt I; Klinik für Neuropädiatrie und angeborene Stoffwechselerkrankungen, Klinikum Oldenburg, 26133 Oldenburg, Germany.
Alawi M; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Steindl K; Institute of Medical Genetics, University of Zürich, 8952 Schlieren, Switzerland.
Joset P; Institute of Medical Genetics, University of Zürich, 8952 Schlieren, Switzerland.
Rauch A; Institute of Medical Genetics, University of Zürich, 8952 Schlieren, Switzerland.
Zwijnenburg PJG; Department of Clinical Genetics, Amsterdam University Medical Center, 1081 Amsterdam, the Netherlands.
Weiss MM; Department of Clinical Genetics, Amsterdam University Medical Center, 1081 Amsterdam, the Netherlands.
Merry CLR; Nottingham Biodiscovery Institute, University of Nottingham, University Park NG7 2RD, UK.
Kutsche K; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: .
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Źródło :
American journal of human genetics [Am J Hum Genet] 2020 Dec 03; Vol. 107 (6), pp. 1044-1061. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone and Bones/*abnormalities
Corpus Callosum/*pathology
Developmental Disabilities/*genetics
Kidney/*abnormalities
Sulfotransferases/*genetics
Adolescent ; Alleles ; Biopsy ; Child ; Child, Preschool ; Extracellular Matrix/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Family Health ; Female ; Fibroblasts/metabolism ; Genetic Variation ; Heparitin Sulfate/metabolism ; Humans ; Iduronic Acid/pharmacology ; Infant, Newborn ; Male ; Pedigree ; Phenotype ; Syndrome ; Urogenital Abnormalities/genetics
SCR Disease Name :
Renal Adysplasia
Czasopismo naukowe
Tytuł :
Heparanase, cell signaling, and viral infections.
Autorzy :
Koganti R; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W. Taylor St, Chicago, IL, 60612, USA.
Suryawanshi R; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W. Taylor St, Chicago, IL, 60612, USA.
Shukla D; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1855 W. Taylor St, Chicago, IL, 60612, USA. .; Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, 60612, USA. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Dec; Vol. 77 (24), pp. 5059-5077. Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Glucuronidase/*genetics
Neoplasms/*genetics
Virus Diseases/*genetics
Extracellular Matrix/genetics ; Glucuronidase/metabolism ; Heparitin Sulfate/metabolism ; Humans ; Immunity, Cellular/genetics ; Neoplasms/pathology ; Neoplasms/virology ; Signal Transduction/genetics ; Virus Diseases/immunology ; Virus Diseases/virology
Czasopismo naukowe

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