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Wyszukujesz frazę ""Herbert, Andrew S."" wg kryterium: Autor


Wyświetlanie 1-20 z 20
Tytuł :
Development of an antibody cocktail for treatment of Sudan virus infection.
Autorzy :
Herbert AS; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.; The Geneva Foundation, Tacoma, WA 98402.
Froude JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Ortiz RA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Kuehne AI; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Dorosky DE; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Bakken RR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Zak SE; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.; The Geneva Foundation, Tacoma, WA 98402.
Josleyn NM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.; The Geneva Foundation, Tacoma, WA 98402.
Musiychuk K; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE 19711.
Jones RM; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE 19711.
Green B; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE 19711.
Streatfield SJ; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE 19711.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Bohorova N; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Bohorov O; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Kim DH; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Pauly MH; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Velasco J; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Whaley KJ; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Stonier SW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.; The Geneva Foundation, Tacoma, WA 98402.
Bornholdt ZA; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Zeitlin L; Mapp Biopharmaceutical, Inc., San Diego, CA 92121.
Sampey D; BioFactura, Inc., Frederick, MD 21701.
Yusibov V; Fraunhofer USA Center for Molecular Biotechnology, Newark, DE 19711.
Dye JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Feb 18; Vol. 117 (7), pp. 3768-3778. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Viral/*administration & dosage
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*drug therapy
Animals ; Antibodies, Monoclonal/administration & dosage ; Disease Models, Animal ; Ebolavirus/genetics ; Female ; Glycoproteins/immunology ; Hemorrhagic Fever, Ebola/virology ; Humans ; Immunotherapy ; Macaca mulatta ; Male ; Mice ; Viral Proteins/immunology
Czasopismo naukowe
Tytuł :
Multiple viral proteins and immune response pathways act to generate robust long-term immunity in Sudan virus survivors.
Autorzy :
Sobarzo A; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. Electronic address: .
Stonier SW; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702-5011, USA.
Radinsky O; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Gelkop S; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Kuehne AI; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702-5011, USA.
Edri A; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Herbert AS; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702-5011, USA.
Fedida-Metula S; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Lutwama JJ; Department of Arbovirology, Emerging and Re-Emerging Infection Uganda Virus Research Institute, Plot No: 51 -59, Nakiwogo Road, P.O.Box 49, Entebbe, Uganda.
Yavelsky V; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel; Department of Arbovirology, Emerging and Re-Emerging Infection Uganda Virus Research Institute, Plot No: 51 -59, Nakiwogo Road, P.O.Box 49, Entebbe, Uganda.
Davis C; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Porgador A; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.
Dye JM; US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Fort Detrick, MD 21702-5011, USA. Electronic address: .
Lobel L; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel; Department of Arbovirology, Emerging and Re-Emerging Infection Uganda Virus Research Institute, Plot No: 51 -59, Nakiwogo Road, P.O.Box 49, Entebbe, Uganda.
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Źródło :
EBioMedicine [EBioMedicine] 2019 Aug; Vol. 46, pp. 215-226. Date of Electronic Publication: 2019 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Immunity*
Antigens, Viral/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*immunology
Host-Pathogen Interactions/*immunology
Viral Proteins/*immunology
Adult ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Biomarkers ; Disease Outbreaks ; Female ; Hemorrhagic Fever, Ebola/epidemiology ; Hemorrhagic Fever, Ebola/metabolism ; Hemorrhagic Fever, Ebola/virology ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Immunologic Memory ; Male ; Middle Aged ; Neutralization Tests ; Signal Transduction ; Survivors ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.
Autorzy :
Bornholdt ZA; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Herbert AS; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA.
Mire CE; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Cross RW; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Abelson DM; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Geisbert JB; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
James RM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA.
Rahim MN; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada.
Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Borisevich V; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Banadyga L; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Gunn BM; The Ragon Institute, Cambridge, MA, USA.
Agans KN; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Wirchnianski AS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Goodwin E; Adimab LLC, Lebanon, NH, USA.
Tierney K; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada.
Shestowsky WS; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Bohorov O; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Bohorova N; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Velasco J; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Ailor E; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Kim D; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Pauly MH; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Whaley KJ; Mapp Biopharmaceutical, Inc., San Diego, CA, USA.
Alter G; The Ragon Institute, Cambridge, MA, USA.
Walker LM; Adimab LLC, Lebanon, NH, USA.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Zeitlin L; Mapp Biopharmaceutical, Inc., San Diego, CA, USA. Electronic address: .
Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada. Electronic address: .
Geisbert TW; Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA. Electronic address: .
Dye JM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2019 Jan 09; Vol. 25 (1), pp. 49-58.e5.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*therapeutic use
Antibodies, Viral/*immunology
Antibodies, Viral/*therapeutic use
Ebolavirus/*pathogenicity
Ferrets/*virology
Hemorrhagic Fever, Ebola/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Animal Welfare ; Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/administration & dosage ; Cell Line ; Chlorocebus aethiops ; Disease Models, Animal ; Female ; Filoviridae/immunology ; Filoviridae Infections/immunology ; Filoviridae Infections/prevention & control ; Filoviridae Infections/virology ; Glycoproteins/immunology ; Guinea Pigs ; HEK293 Cells ; Hemorrhagic Fever, Ebola/virology ; Humans ; Killer Cells, Natural ; Macaca ; Macaca fascicularis ; Male ; Primates ; Survival Analysis ; Treatment Outcome ; Viral Proteins/immunology
Czasopismo naukowe
Tytuł :
Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.
Autorzy :
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Bornholdt ZA; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Goodwin E; Adimab, LLC, Lebanon, NH 03766, USA.
Wirchnianski AS; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Gunn BM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Zhang Z; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Liu G; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Abelson DM; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Moyer CL; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
James RM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Bakken RR; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Bohorova N; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Bohorov O; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Kim DH; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Pauly MH; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Velasco J; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Bortz RH 3rd; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Whaley KJ; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Goldstein T; One Health Institute and Karen C. Drayer Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA.
Anthony SJ; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Walker LM; Adimab, LLC, Lebanon, NH 03766, USA.
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Zeitlin L; Mapp Biopharmaceutical, San Diego, CA 92121, USA. Electronic address: .
Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada. Electronic address: .
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2019 Jan 09; Vol. 25 (1), pp. 39-48.e5.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Viral/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Animal Welfare ; Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/administration & dosage ; Antibodies, Viral/therapeutic use ; Antiviral Agents ; Disease Models, Animal ; Ebolavirus/pathogenicity ; Epitopes/immunology ; Female ; Filoviridae/immunology ; Guinea Pigs ; Hemorrhagic Fever, Ebola/virology ; Humans ; Immunotherapy ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Recombinant Proteins/immunology ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.
Autorzy :
Saphire EO; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
Schendel SL; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Fusco ML; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Gunn BM; Ragon Institute, Cambridge, MA 02139, USA.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Halfmann PJ; Division of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706, USA.
Brannan JM; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA.
Herbert AS; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA.
Qiu X; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg R3E 3R2, Canada.
Wagh K; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
He S; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg R3E 3R2, Canada.
Giorgi EE; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Theiler J; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Pommert KBJ; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Krause TB; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Turner HL; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Murin CD; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Pallesen J; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
Ahmed R; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Aman MJ; Integrated BioTherapeutics, Rockville, MD 20850, USA.
Bukreyev A; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA.
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Crowe JE Jr; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Davis CW; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Georgiou G; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Kyratsous CA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.
Lai JR; Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Nykiforuk C; Emergent BioSolutions, Winnipeg, Manitoba, R3T 5Y3, Canada.
Pauly MH; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Rijal P; Human Immunology Unit, University of Oxford, Oxford OX3 9DS, UK.
Takada A; Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Townsend AR; Human Immunology Unit, University of Oxford, Oxford OX3 9DS, UK.
Volchkov V; INSERM CNRS, Université Lyon, Lyon, France.
Walker LM; Adimab, LLC. Lebanon, NH 03766, USA.
Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), Biopolis 138648, Singapore.
Zeitlin L; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
Ward AB; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Korber B; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Kobinger GP; Département de Microbiologie-Infectiologie et d'Immunologie, Médecine, Université Laval Quebec, G1V 046 Canada. Electronic address: .
Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: .
Kawaoka Y; Division of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706, USA. Electronic address: .
Alter G; Ragon Institute, Cambridge, MA 02139, USA. Electronic address: .
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: .
Dye JM; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA. Electronic address: .
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Corporate Authors :
Viral Hemorrhagic Fever Immunotherapeutic Consortium
Źródło :
Cell [Cell] 2018 Aug 09; Vol. 174 (4), pp. 938-952.e13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*isolation & purification
Ebolavirus/*immunology
Epitopes/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Membrane Glycoproteins/*immunology
Animals ; Antibodies, Monoclonal/administration & dosage ; Female ; Hemorrhagic Fever, Ebola/immunology ; Hemorrhagic Fever, Ebola/virology ; Immunization ; Mice ; Mice, Inbred BALB C ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.
Autorzy :
Gunn BM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Yu WH; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Karim MM; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Brannan JM; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Herbert AS; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Halfmann PJ; Department of Pathobiological Sciences, School of Veterinary Medicine, Influenza Research Institute, University of Wisconsin, Madison, WI 53706, USA.
Fusco ML; Department of Immunology and Microbiology, The Scripps Research Institute, The Skaggs Institute for Chemical Biology, La Jolla, CA 92037, USA.
Schendel SL; Department of Immunology and Microbiology, The Scripps Research Institute, The Skaggs Institute for Chemical Biology, La Jolla, CA 92037, USA.
Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, The Skaggs Institute for Chemical Biology, La Jolla, CA 92037, USA.
Krause T; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Qiu X; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada.
He S; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada.
Das J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Suscovich TJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
Lai J; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Zeitlin L; Mapp Biopharmaceutical, Inc., San Diego, CA 92121, USA.
Crowe JE Jr; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
Lauffenburger D; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kawaoka Y; Department of Pathobiological Sciences, School of Veterinary Medicine, Influenza Research Institute, University of Wisconsin, Madison, WI 53706, USA.
Kobinger GP; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Université Laval Quebec, Québec, QC G1V 0A6, Canada.
Andersen KG; Department of Immunology and Microbial Science, Scripps Translational Science Institute, Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Dye JM; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Saphire EO; Department of Immunology and Microbiology, The Scripps Research Institute, The Skaggs Institute for Chemical Biology, La Jolla, CA 92037, USA. Electronic address: .
Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA. Electronic address: .
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Źródło :
Cell host & microbe [Cell Host Microbe] 2018 Aug 08; Vol. 24 (2), pp. 221-233.e5.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Immunoglobulin Fc Fragments/*immunology
Animals ; Antibodies, Monoclonal/pharmacology ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Female ; Hemorrhagic Fever, Ebola/immunology ; Humans ; Killer Cells, Natural/immunology ; Mice ; Mice, Inbred BALB C ; Neutralization Tests ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail.
Autorzy :
Froude JW; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. .
Herbert AS; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. andrew.s..
Pelat T; Unite de Biotechnologie des Anticorps, Institut de Recherche Biomedicale des Armees (IRBA-CRSSA), La Tronche 38516, France. .
Miethe S; Institut für Biochemie, Biotechnologie und Bioinformatik, Technische Universität Braunschweig, Braunschweig 38106, Germany. .
Zak SE; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. .
Brannan JM; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. .
Bakken RR; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. .
Steiner AR; Sutro Biopharma Inc., South San Francisco, CA 94080, USA. .
Yin G; Sutro Biopharma Inc., South San Francisco, CA 94080, USA. .
Hallam TJ; Sutro Biopharma Inc., South San Francisco, CA 94080, USA. .
Sato AK; Sutro Biopharma Inc., South San Francisco, CA 94080, USA. .
Hust M; Institut für Biochemie, Biotechnologie und Bioinformatik, Technische Universität Braunschweig, Braunschweig 38106, Germany. .
Thullier P; Unite de Biotechnologie des Anticorps, Institut de Recherche Biomedicale des Armees (IRBA-CRSSA), La Tronche 38516, France. .
Dye JM; US Army Medical Research Institute for Infectious Disease (USAMRIID), Fort Detrick, MD 21702, USA. .
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Źródło :
Viruses [Viruses] 2018 May 26; Vol. 10 (6). Date of Electronic Publication: 2018 May 26.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Ebolavirus*
Post-Exposure Prophylaxis*
Antibodies, Viral/*pharmacology
Hemorrhagic Fever, Ebola/*therapy
Membrane Glycoproteins/*immunology
Vaccines, Virus-Like Particle/*immunology
Viral Matrix Proteins/*immunology
Animals ; Antibodies, Neutralizing/pharmacology ; Cell Surface Display Techniques ; Cross Reactions ; Female ; Macaca ; Male ; Mice ; Mice, Knockout ; Single-Chain Antibodies/pharmacology ; Vaccination
Czasopismo naukowe
Tytuł :
Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.
Autorzy :
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Murin CD; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Abelson DM; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Fels JM; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
James RM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
de La Vega MA; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Zhu W; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Bakken RR; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Goodwin E; Adimab, LLC, Lebanon, NH 03766, USA.
Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Zeitlin L; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Walker LM; Adimab, LLC, Lebanon, NH 03766, USA.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA. Electronic address: .
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: .
Bornholdt ZA; Mapp Biopharmaceutical, San Diego, CA 92121, USA. Electronic address: .
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Źródło :
Cell [Cell] 2017 May 18; Vol. 169 (5), pp. 878-890.e15.
Typ publikacji :
Journal Article
MeSH Terms :
Survivors*
Antibodies, Neutralizing/*isolation & purification
Antibodies, Viral/*isolation & purification
Ebola Vaccines/*immunology
Hemorrhagic Fever, Ebola/*immunology
Amino Acid Sequence ; Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; Chlorocebus aethiops ; Cross Reactions ; Ebolavirus/classification ; Ebolavirus/immunology ; Female ; Ferrets ; Hemorrhagic Fever, Ebola/virology ; Humans ; Kinetics ; Mice ; Mice, Inbred BALB C ; Models, Molecular ; Sequence Alignment ; Vero Cells
Czasopismo naukowe
Tytuł :
Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease.
Autorzy :
Kash JC; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Walters KA; Institute for Systems Biology, Seattle, WA 98109, USA.
Kindrachuk J; Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA.
Baxter D; Institute for Systems Biology, Seattle, WA 98109, USA.
Scherler K; Institute for Systems Biology, Seattle, WA 98109, USA.
Janosko KB; Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD 21702, USA.
Adams RD; Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD 21702, USA.
Herbert AS; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
James RM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Stonier SW; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Memoli MJ; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Dye JM; United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA.
Davey RT Jr; Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Chertow DS; Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892, USA.
Taubenberger JK; Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. .
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Źródło :
Science translational medicine [Sci Transl Med] 2017 Apr 12; Vol. 9 (385).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Intramural
MeSH Terms :
Ebolavirus/*pathogenicity
Hemorrhagic Fever, Ebola/*virology
Leukocytes/*metabolism
Disease Outbreaks ; Hemorrhagic Fever, Ebola/blood ; Humans ; Longitudinal Studies ; RNA, Viral/blood ; RNA, Viral/genetics ; Virus Replication/physiology
Czasopismo naukowe
Tytuł :
Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus.
Autorzy :
Howell KA; Integrated BioTherapeutics, Inc., Rockville, MD 20850, USA.
Brannan JM; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702-5011, USA.
Bryan C; Integral Molecular, Philadelphia, PA 19104, USA.
McNeal A; Integral Molecular, Philadelphia, PA 19104, USA.
Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Vu H; Integrated BioTherapeutics, Inc., Rockville, MD 20850, USA.
Shulenin S; Integrated BioTherapeutics, Inc., Rockville, MD 20850, USA.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Kuehne A; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702-5011, USA.
Herbert AS; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702-5011, USA.
Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
Holtsberg FW; Integrated BioTherapeutics, Inc., Rockville, MD 20850, USA.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Dye JM; US Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702-5011, USA.
Aman MJ; Integrated BioTherapeutics, Inc., Rockville, MD 20850, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2017 Apr 11; Vol. 19 (2), pp. 413-424.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*immunology
Animals ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/therapeutic use ; Drug Synergism ; Ebolavirus/pathogenicity ; Hemorrhagic Fever, Ebola/therapy ; Hemorrhagic Fever, Ebola/virology ; Humans ; Mice
Czasopismo naukowe
Tytuł :
A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
Autorzy :
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Howell KA; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Holtsberg FW; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Bakken RR; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Mittler E; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Christin JR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Shulenin S; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA.
Jangra RK; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Bharrhan S; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Kuehne AI; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Bornholdt ZA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 10550, USA.
Flyak AI; Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN 37235, USA.
Saphire EO; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 10550, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 10550, USA.
Crowe JE Jr; Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN 37235, USA. .; Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA.; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232, USA.
Aman MJ; Integrated Biotherapeutics Inc., Gaithersburg, MD 20878, USA. .
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA. .
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA. .
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. .
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Źródło :
Science (New York, N.Y.) [Science] 2016 Oct 21; Vol. 354 (6310), pp. 350-354. Date of Electronic Publication: 2016 Sep 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Bispecific/*immunology
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
Carrier Proteins/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Membrane Glycoproteins/*immunology
Receptors, Virus/*immunology
Viral Envelope Proteins/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Binding Sites/immunology ; Cell Line, Tumor ; Endosomes/virology ; Hemorrhagic Fever, Ebola/therapy ; Humans ; Immunotherapy/methods ; Intracellular Signaling Peptides and Proteins ; Mice ; Mice, Inbred BALB C ; Virus Internalization
Czasopismo naukowe
Tytuł :
Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site.
Autorzy :
Howell KA; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Qiu X; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Brannan JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Bryan C; Integral Molecular, Philadelphia, PA 19104, USA.
Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
Holtsberg FW; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Shulenin S; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Biggins JE; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Douglas R; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Enterlein SG; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Turner HL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Pallesen J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Murin CD; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
He S; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Kroeker A; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Vu H; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Fusco ML; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.
Nyakatura EK; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Lai JR; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Keck ZY; Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Foung SKH; Department of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Saphire EO; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Zeitlin L; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
Kobinger GP; Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB R3E 3R2, Canada; Deparment of Medical Microbiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.
Aman MJ; Integrated BioTherapeutics, Inc., Gaithersburg, MD 20878, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2016 May 17; Vol. 15 (7), pp. 1514-1526. Date of Electronic Publication: 2016 May 05.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*therapeutic use
Ebolavirus/*physiology
Epitopes/*immunology
Glycoproteins/*metabolism
Hemorrhagic Fever, Ebola/*immunology
Receptors, Virus/*metabolism
Amino Acid Sequence ; Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/ultrastructure ; Antibodies, Neutralizing ; Antibodies, Viral/chemistry ; Binding Sites ; Disease Models, Animal ; Female ; Glycoproteins/chemistry ; Glycoproteins/genetics ; Glycoproteins/ultrastructure ; Guinea Pigs ; HEK293 Cells ; Humans ; Kinetics ; Mice, Inbred BALB C ; Models, Molecular ; Mutation/genetics ; Negative Staining ; Neutralization Tests ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Correspondence of Neutralizing Humoral Immunity and CD4 T Cell Responses in Long Recovered Sudan Virus Survivors.
Autorzy :
Sobarzo A; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Stonier SW; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. .
Herbert AS; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. anderw.s.herbert..
Ochayon DE; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Kuehne AI; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. .
Eskira Y; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Fedida-Metula S; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Tali N; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Lewis EC; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Egesa M; Medical Research Council/Uganda Virus Research Institute, Uganda Research Unit on AIDS, Entebbe P.O. Box 49, Uganda. .; Department of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala P.O. Box 7072, Uganda. .
Cose S; Medical Research Council/Uganda Virus Research Institute, Uganda Research Unit on AIDS, Entebbe P.O. Box 49, Uganda. .; London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK. .
Lutwama JJ; Department of Arbovirology, Emerging and Re-Emerging Infection Uganda Virus Research Institute, Entebbe P.O. Box 49, Uganda. .
Yavelsky V; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
Dye JM; Virology Division, U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. .
Lobel L; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. .
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Źródło :
Viruses [Viruses] 2016 May 11; Vol. 8 (5). Date of Electronic Publication: 2016 May 11.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Neutralizing/*blood
Antibodies, Viral/*blood
CD4-Positive T-Lymphocytes/*immunology
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*immunology
Cytokines/biosynthesis ; Enzyme-Linked Immunosorbent Assay ; Flow Cytometry ; Humans ; Neutralization Tests ; Survivors ; Uganda
Czasopismo naukowe
Tytuł :
Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle.
Autorzy :
Dye JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Wu H; SAB Biotherapeutics, Sioux Falls, South Dakota, United States of America.
Hooper JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, Maryland, USA.
Kuehne AI; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Coyle EM; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, Maryland, USA.
Ortiz RA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Fuentes S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, Maryland, USA.
Herbert AS; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Golding H; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, Maryland, USA.
Bakken RA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Brannan JM; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Kwilas SA; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, USA.
Sullivan EJ; SAB Biotherapeutics, Sioux Falls, South Dakota, United States of America.
Luke TC; Viral and Rickettsial Diseases Department, Navy Medical Research Center, The Henry Jackson Foundation, Silver Spring, Maryland, USA.
Smith G; Novavax Inc, Gaithersburg, Maryland, USA.
Glenn G; Novavax Inc, Gaithersburg, Maryland, USA.
Li W; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University, Atlanta, Georgia, 30322, USA.
Ye L; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University, Atlanta, Georgia, 30322, USA.
Yang C; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University, Atlanta, Georgia, 30322, USA.
Compans RW; Department of Microbiology and Immunology and Emory Vaccine Center, Emory University, Atlanta, Georgia, 30322, USA.
Tripp RA; The University of Georgia, Athens, Georgia, 30602, USA.
Jiao JA; SAB Biotherapeutics, Sioux Falls, South Dakota, United States of America.
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Źródło :
Scientific reports [Sci Rep] 2016 Apr 25; Vol. 6, pp. 24897. Date of Electronic Publication: 2016 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animals, Genetically Modified*
Cattle*
Antibodies, Viral/*blood
Antibodies, Viral/*therapeutic use
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Animals ; Disease Models, Animal ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunization, Passive ; Immunoglobulin G/blood ; Immunoglobulin G/therapeutic use ; Mice, Inbred BALB C ; Neutralization Tests ; Surface Plasmon Resonance ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein.
Autorzy :
Keck ZY; Department of Pathology, Stanford University, Stanford, California, USA.
Enterlein SG; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Howell KA; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Vu H; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Shulenin S; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Warfield KL; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Froude JW; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Araghi N; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Douglas R; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Biggins J; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Lear-Rooney CM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Wirchnianski AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Lau P; Department of Pathology, Stanford University, Stanford, California, USA.
Wang Y; Department of Pathology, Stanford University, Stanford, California, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Glass PJ; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Holtsberg FW; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Foung SK; Department of Pathology, Stanford University, Stanford, California, USA.
Aman MJ; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA .
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Źródło :
Journal of virology [J Virol] 2015 Oct 14; Vol. 90 (1), pp. 279-91. Date of Electronic Publication: 2015 Oct 14 (Print Publication: 2016).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Viral/*immunology
Epitopes/*immunology
Filoviridae/*immunology
Glycoproteins/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Viral Proteins/*immunology
Animals ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/isolation & purification ; Antibodies, Viral/therapeutic use ; Cross Reactions ; Disease Models, Animal ; Female ; Immunization, Passive ; Macaca ; Mice, Inbred BALB C ; Survival Analysis ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses.
Autorzy :
Holtsberg FW; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Shulenin S; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Vu H; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Howell KA; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Patel SJ; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Gunn B; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Boston, Massachusetts, USA.
Karim M; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Boston, Massachusetts, USA.
Lai JR; Albert Einstein College of Medicine, New York, New York, USA.
Frei JC; Albert Einstein College of Medicine, New York, New York, USA.
Nyakatura EK; Albert Einstein College of Medicine, New York, New York, USA.
Zeitlin L; Mapp Biopharmaceutical, San Diego, California, USA.
Douglas R; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Fusco ML; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA.
Froude JW; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Saphire EO; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA.
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Wirchnianski AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Lear-Rooney CM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Boston, Massachusetts, USA.
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Glass PJ; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA.
Warfield KL; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA.
Aman MJ; Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA .
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Źródło :
Journal of virology [J Virol] 2015 Oct 14; Vol. 90 (1), pp. 266-78. Date of Electronic Publication: 2015 Oct 14 (Print Publication: 2016).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunization, Passive*
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*isolation & purification
Antibodies, Viral/*immunology
Antibodies, Viral/*isolation & purification
Filoviridae/*immunology
Hemorrhagic Fever, Ebola/*prevention & control
Animals ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Neutralizing/administration & dosage ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/isolation & purification ; Antibodies, Viral/administration & dosage ; Cross Protection ; Disease Models, Animal ; Epitopes/immunology ; Female ; Mice, Inbred BALB C ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Novel Small Molecule Entry Inhibitors of Ebola Virus.
Autorzy :
Basu A; Microbiotix, Inc, Worcester, Massachusetts.
Mills DM; Microbiotix, Inc, Worcester, Massachusetts.
Mitchell D; Texas Biomedical Research Institute, San Antonio.
Ndungo E; Albert Einstein College of Medicine, Bronx, New York.
Williams JD; Microbiotix, Inc, Worcester, Massachusetts.
Herbert AS; Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.
Dye JM; Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.
Moir DT; Microbiotix, Inc, Worcester, Massachusetts.
Chandran K; Albert Einstein College of Medicine, Bronx, New York.
Patterson JL; Texas Biomedical Research Institute, San Antonio.
Rong L; Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago.
Bowlin TL; Microbiotix, Inc, Worcester, Massachusetts.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2015 Oct 01; Vol. 212 Suppl 2, pp. S425-34. Date of Electronic Publication: 2015 Jul 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antiviral Agents/*pharmacology
Ebolavirus/*drug effects
Hemorrhagic Fever, Ebola/*drug therapy
Hemorrhagic Fever, Ebola/*virology
Small Molecule Libraries/*pharmacology
Animals ; Carrier Proteins/metabolism ; Cell Line ; Chlorocebus aethiops ; Glycoproteins/metabolism ; HEK293 Cells ; Humans ; Intracellular Signaling Peptides and Proteins ; Membrane Glycoproteins/metabolism ; Protein Binding/drug effects ; Vero Cells ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł :
Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.
Autorzy :
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
Davidson C; Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA.
Kuehne AI; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
Bakken R; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
Braigen SZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Gunn KE
Whelan SP; Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, USA.
Brummelkamp TR; Netherlands Cancer Institute, Amsterdam, The Netherlands.
Twenhafel NA; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA .
Walkley SU; Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA .
Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA .
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Źródło :
MBio [mBio] 2015 May 26; Vol. 6 (3), pp. e00565-15. Date of Electronic Publication: 2015 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
Host-Pathogen Interactions*
Virus Replication*
Ebolavirus/*physiology
Hemorrhagic Fever, Ebola/*virology
Proteins/*metabolism
Animals ; Cholesterol/metabolism ; Disease Models, Animal ; Intracellular Signaling Peptides and Proteins ; Mice ; Mice, Knockout ; Proteins/genetics ; Vesicular Transport Proteins/deficiency ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Tytuł :
Immune memory to Sudan virus: comparison between two separate disease outbreaks.
Autorzy :
Sobarzo A; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Eskira Y; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Herbert AS; Virology Division-U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. anderw.s.herbert..
Kuehne AI; Virology Division-U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. .
Stonier SW; Virology Division-U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. spencer.w.stonier2..
Ochayon DE; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Fedida-Metula S; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Balinandi S; Department of Arbovirology, Emerging and Re-emerging Infection Uganda Virus Research Institute, Entebbe P.O Box 49, Uganda. .
Kislev Y; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Tali N; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Lewis EC; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Lutwama JJ; Department of Arbovirology, Emerging and Re-emerging Infection Uganda Virus Research Institute, Entebbe P.O Box 49, Uganda. .
Dye JM; Virology Division-U.S. Army Medical Research Institute of Infectious Diseases, 1425 Porter St., Fort Detrick, Frederick, MD 21701, USA. .
Yavelsky V; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
Lobel L; Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel. .
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Źródło :
Viruses [Viruses] 2015 Jan 06; Vol. 7 (1), pp. 37-51. Date of Electronic Publication: 2015 Jan 06.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Outbreaks*
Immunologic Memory*
Ebolavirus/*immunology
Hemorrhagic Fever, Ebola/*epidemiology
Hemorrhagic Fever, Ebola/*immunology
Antibodies, Viral/blood ; Cohort Studies ; Cross Reactions ; Cytokines/metabolism ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunity, Cellular ; Immunoglobulin G/blood ; Neutralization Tests ; Sudan ; Survivors ; Uganda/epidemiology
Czasopismo naukowe
Tytuł :
Venezuelan equine encephalitis virus replicon particle vaccine protects nonhuman primates from intramuscular and aerosol challenge with ebolavirus.
Autorzy :
Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland, USA.
Kuehne AI
Barth JF
Ortiz RA
Nichols DK
Zak SE
Stonier SW
Muhammad MA
Bakken RR
Prugar LI
Olinger GG
Groebner JL
Lee JS
Pratt WD
Custer M
Kamrud KI
Smith JF
Hart MK
Dye JM
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Źródło :
Journal of virology [J Virol] 2013 May; Vol. 87 (9), pp. 4952-64. Date of Electronic Publication: 2013 Feb 13.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Replicon*
Ebolavirus/*immunology
Encephalitis Virus, Venezuelan Equine/*genetics
Hemorrhagic Fever, Ebola/*prevention & control
Viral Vaccines/*immunology
Animals ; Antibodies, Viral/immunology ; Ebolavirus/genetics ; Encephalitis Virus, Venezuelan Equine/physiology ; Genetic Vectors/genetics ; Genetic Vectors/physiology ; Hemorrhagic Fever, Ebola/immunology ; Hemorrhagic Fever, Ebola/virology ; Humans ; Macaca fascicularis ; Vaccination ; Viral Envelope Proteins/administration & dosage ; Viral Envelope Proteins/genetics ; Viral Envelope Proteins/immunology ; Viral Vaccines/administration & dosage ; Viral Vaccines/genetics
Czasopismo naukowe
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