- Tytuł:
- Ebola virus entry requires the cholesterol transporter Niemann-Pick C1.
- Autorzy:
- Źródło:
- Nature [Nature] 2011 Aug 24; Vol. 477 (7364), pp. 340-3. Date of Electronic Publication: 2011 Aug 24.
- Typ publikacji:
-
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.
S . Gov't; Research Support, U.S . Gov't, Non-P.H.S . - MeSH Terms:
-
Virus Internalization*
Carrier Proteins/*metabolism
Cholesterol/*metabolismEbolavirus /*physiology
Membrane Glycoproteins/*metabolism
Animals ; Biological Transport ; Carrier Proteins/genetics ; Cell Line ; Endosomes/metabolism ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Fibroblasts/virology ; Genome, Human/genetics ; Glycoproteins/metabolism ; Haploidy ; Hemorrhagic Fever, Ebola/drug therapy ; Hemorrhagic Fever, Ebola/metabolism ; Host-Pathogen Interactions/genetics ; Humans ; Intracellular Signaling Peptides and Proteins ; Lysosomes/metabolism ; Marburg Virus Disease/drug therapy ; Marburg Virus Disease/metabolism ; Marburgvirus/physiology ; Membrane Fusion/genetics ; Membrane Fusion/physiology ; Membrane Glycoproteins/deficiency ; Membrane Glycoproteins/genetics ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/deficiency ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Mutation/genetics ; Niemann-Pick C1 Protein ; Niemann-Pick Diseases/pathology ; Niemann-Pick Diseases/virology ; Receptors, Virus/metabolism ; Vesicular Transport Proteins ; Viral Fusion Proteins/metabolism
Czasopismo naukowe