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Wyszukujesz frazę ""Hereditary Breast and Ovarian Cancer Syndrome"" wg kryterium: Temat


Tytuł :
A synergetic effect of BARD1 mutations on tumorigenesis.
Autorzy :
Li W; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology (Peking University Third Hospital), Beijing, China.
Gu X; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology (Peking University Third Hospital), Beijing, China.
Liu C; Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Shi Y; Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China.
Wang P; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Zhang N; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Wu R; Department of Pathology, Peking University Third Hospital, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Leng L; Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, China Academy of Chinese Medical Sciences, Institute of Chinese Materia Medica, Beijing, China.
Xie B; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.
Song C; Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.
Li M; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. .; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China. .; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology (Peking University Third Hospital), Beijing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Feb 23; Vol. 12 (1), pp. 1243. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenesis/*genetics
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Mutation/*genetics
Tumor Suppressor Proteins/*genetics
Ubiquitin-Protein Ligases/*genetics
Adult ; Animals ; BRCA1 Protein/genetics ; Cell Line, Tumor ; Cell Nucleus/metabolism ; DNA Damage ; DNA Mutational Analysis ; Female ; Genomic Instability/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Humans ; Male ; Mice ; Pedigree ; Peptides/metabolism ; Protein Binding ; Tumor Suppressor Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Risk factors for lymph node metastasis of ovarian, fallopian tube and primary peritoneal cancer in hereditary breast and ovarian cancer syndrome.
Autorzy :
Mitamura T; Department of Obstetrics and Gynecology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo.; Division of Clinical Genetics, Hokkaido University Hospital, Sapporo.
Sekine M; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata.
Arai M; Clinical Genetics, Juntendo University, Graduate School of Medicine, Tokyo.
Shibata Y; Division of Clinical Genetics, Hokkaido University Hospital, Sapporo.
Kato M; Division of Clinical Genetics, Hokkaido University Hospital, Sapporo.
Yokoyama S; Division of Breast Surgical Oncology, Department of Surgery, Showa University School of Medicine, Tokyo.
Yamashita H; Department of Breast Surgery, Hokkaido University Hospital, Sapporo.
Watari H; Department of Obstetrics and Gynecology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo.
Yabe I; Division of Clinical Genetics, Hokkaido University Hospital, Sapporo.
Nomura H; Department of Obstetrics and Gynecology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.
Enomoto T; Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata.
Nakamura S; Division of Breast Surgical Oncology, Department of Surgery, Showa University School of Medicine, Tokyo.
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Corporate Authors :
Registration Committee of the Japanese HBOC Consortium
Źródło :
Japanese journal of clinical oncology [Jpn J Clin Oncol] 2020 Dec 16; Vol. 50 (12), pp. 1380-1385.
Typ publikacji :
Journal Article
MeSH Terms :
Fallopian Tube Neoplasms/*pathology
Hereditary Breast and Ovarian Cancer Syndrome/*pathology
Ovarian Neoplasms/*pathology
Peritoneal Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Fallopian Tube Neoplasms/genetics ; Female ; Genetic Predisposition to Disease ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Humans ; Japan/epidemiology ; Lymphatic Metastasis ; Middle Aged ; Mutation ; Ovarian Neoplasms/genetics ; Penetrance ; Peritoneal Neoplasms/genetics ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Molecular Features and Clinical Management of Hereditary Gynecological Cancers.
Autorzy :
Ueki A; Center for Medical Genetics, Keio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Hirasawa A; Department of Clinical Genomic Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 14; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Breast Neoplasms/*metabolism
Breast Neoplasms/*pathology
Colorectal Neoplasms, Hereditary Nonpolyposis/*metabolism
Colorectal Neoplasms, Hereditary Nonpolyposis/*pathology
Hereditary Breast and Ovarian Cancer Syndrome/*pathology
Breast Neoplasms/genetics ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Female ; Genetic Predisposition to Disease/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/metabolism ; High-Throughput Nucleotide Sequencing ; Humans
SCR Disease Name :
Breast Cancer, Familial
Czasopismo naukowe
Tytuł :
Pathogenicity reclassification of two BRCA1/BRCA2 exonic duplications after identification of genomic breakpoints and tandem orientation.
Autorzy :
Pinheiro M; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Peixoto A; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Santos C; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Escudeiro C; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Bizarro S; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Pinto P; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Santos R; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Pinto C; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Guerra J; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Silva J; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal.
Teixeira MR; Department of Genetics, Portuguese Oncology Institute of Porto, Rua Dr. António Bernardino Almeida, Porto 4200-072, Portugal; Institute of Biomedical Sciences Abel Salazar, University of Porto, Largo Prof. Abel Salazar, Porto 4099-003, Portugal. Electronic address: .
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Źródło :
Cancer genetics [Cancer Genet] 2020 Oct; Vol. 248-249, pp. 18-24. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Breakpoints*
Gene Duplication*
Germ-Line Mutation*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Hereditary Breast and Ovarian Cancer Syndrome/*classification
Hereditary Breast and Ovarian Cancer Syndrome/*pathology
Adult ; Aged ; Exons ; Female ; Follow-Up Studies ; Gene Rearrangement ; Genomics ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Humans ; Male ; Middle Aged ; Pedigree ; Prognosis
Czasopismo naukowe
Tytuł :
[In Situ Ductal Carcinoma with Hereditary Breast and Ovarian Cancer Syndrome in a Patient Who Received Contralateral Risk-Reducing Mastectomy-A Case Report].
Autorzy :
Kosaka Y; Dept. of Breast and Endocrine Surgery, Kitasato University School of Medicine.
Kikuchi M
Nishimiya H
Katoh H
Kawaguchi R
Araki N
Shimazu M
Tsumura H
Waraya M
Takada F
Sengoku N
Sangai T
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Źródło :
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2020 Sep; Vol. 47 (9), pp. 1387-1389.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Breast Neoplasms*/genetics
Breast Neoplasms*/surgery
Carcinoma, Ductal*
Carcinoma, Ductal, Breast*/surgery
Carcinoma, Intraductal, Noninfiltrating*
Hereditary Breast and Ovarian Cancer Syndrome*/genetics
Hereditary Breast and Ovarian Cancer Syndrome*/surgery
Child ; Female ; Humans ; Mastectomy
Czasopismo naukowe
Tytuł :
Prevalence and Spectrum of BRCA Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study.
Autorzy :
Foglietta J; Medical Oncology Division, S. Maria Hospital, 05100 Terni, Italy.
Ludovini V; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Bianconi F; Umbria Cancer Registry, University of Perugia, 06129 Perugia, Italy.
Pistola L; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Reda MS; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Al-Refaie A; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Tofanetti FR; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Mosconi A; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Minenza E; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Anastasi P; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Molica C; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
Stracci F; Department of Experimental Medicine, Public Health Section, University of Perugia, 06129 Perugia, Italy.
Roila F; Medical Oncology Division, S. Maria della Misericordia Hospital, 06132 Perugia, Italy.
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Źródło :
Genes [Genes (Basel)] 2020 Aug 12; Vol. 11 (8). Date of Electronic Publication: 2020 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genes, BRCA1*
Genes, BRCA2*
Germ-Line Mutation*
Hereditary Breast and Ovarian Cancer Syndrome/*epidemiology
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Adult ; Aged ; Aged, 80 and over ; DNA Mutational Analysis ; Female ; Genetic Predisposition to Disease ; Genetic Testing ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Humans ; Immunohistochemistry ; Italy/epidemiology ; Male ; Middle Aged ; Mutation Rate ; Pedigree ; Population Surveillance ; Prevalence ; Risk Assessment ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Population genetic screening efficiently identifies carriers of autosomal dominant diseases.
Autorzy :
Grzymski JJ; Renown Health, Reno, NV, USA. .; Desert Research Institute, Reno, NV, USA. .
Elhanan G; Desert Research Institute, Reno, NV, USA.
Morales Rosado JA; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Smith E; Desert Research Institute, Reno, NV, USA.
Schlauch KA; Desert Research Institute, Reno, NV, USA.
Read R; Desert Research Institute, Reno, NV, USA.
Rowan C; Renown Health, Reno, NV, USA.
Slotnick N; Renown Health, Reno, NV, USA.
Dabe S; Desert Research Institute, Reno, NV, USA.
Metcalf WJ; Desert Research Institute, Reno, NV, USA.
Lipp B; Desert Research Institute, Reno, NV, USA.
Reed H; Desert Research Institute, Reno, NV, USA.
Sharma L; Helix, San Mateo, CA, USA.
Levin E; Helix, San Mateo, CA, USA.
Kao J; Helix, San Mateo, CA, USA.
Rashkin M; Helix, San Mateo, CA, USA.
Bowes J; Helix, San Mateo, CA, USA.
Dunaway K; Helix, San Mateo, CA, USA.
Slonim A; Renown Health, Reno, NV, USA.
Washington N; Helix, San Mateo, CA, USA.
Ferber M; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Bolze A; Helix, San Mateo, CA, USA.
Lu JT; Helix, San Mateo, CA, USA. .
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Źródło :
Nature medicine [Nat Med] 2020 Aug; Vol. 26 (8), pp. 1235-1239. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Testing*
Genetics, Population*
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Hyperlipoproteinemia Type II/*genetics
Adolescent ; Adult ; Aged ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology ; Female ; Genetic Carrier Screening/methods ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Heterozygote ; Humans ; Hyperlipoproteinemia Type II/diagnosis ; Hyperlipoproteinemia Type II/pathology ; Middle Aged
Czasopismo naukowe
Tytuł :
"It wasn't just for me": Motivations and implications of genetic testing for women at a low risk of hereditary breast and ovarian cancer syndrome.
Autorzy :
Gill G; Parkville Familial Cancer Centre and Genomic Medicine Department, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.
Beard C; Parkville Familial Cancer Centre and Genomic Medicine Department, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Parkville, Victoria, Australia.
Storey K; Parkville Familial Cancer Centre and Genomic Medicine Department, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Parkville, Victoria, Australia.
Taylor S; Parkville Familial Cancer Centre and Genomic Medicine Department, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Parkville, Victoria, Australia.
Sexton A; Parkville Familial Cancer Centre and Genomic Medicine Department, Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Parkville, Victoria, Australia.; Department of Medicine, The University of Melbourne, Parkville, Victoria, Australia.
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Źródło :
Psycho-oncology [Psychooncology] 2020 Aug; Vol. 29 (8), pp. 1303-1311. Date of Electronic Publication: 2020 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*psychology
Genetic Testing/*statistics & numerical data
Hereditary Breast and Ovarian Cancer Syndrome/*psychology
Patient Acceptance of Health Care/*psychology
Adult ; Australia ; BRCA1 Protein ; Female ; Genetic Predisposition to Disease/prevention & control ; Genetic Predisposition to Disease/psychology ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Humans ; Middle Aged ; Motivation ; Risk Assessment
SCR Disease Name :
Breast Cancer, Familial
Czasopismo naukowe
Tytuł :
Cancer risk management among female BRCA1/2, PALB2, CHEK2, and ATM carriers.
Autorzy :
Cragun D; College of Public Health, University of South Florida, Tampa, FL, USA.
Weidner A; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Tezak A; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Clouse K; Vanderbilt Institute for Global Health, Vanderbilt University School of Nursing, Nashville, TN, USA.
Pal T; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. .; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, 1500 21st Ave. S., Suite 2810, Nashville, TN, 37212, USA. .
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Źródło :
Breast cancer research and treatment [Breast Cancer Res Treat] 2020 Jul; Vol. 182 (2), pp. 421-428. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Comparative Study; Journal Article; Observational Study
MeSH Terms :
Breast Neoplasms/*prevention & control
Hereditary Breast and Ovarian Cancer Syndrome/*prevention & control
Ovariectomy/*statistics & numerical data
Practice Patterns, Physicians'/*statistics & numerical data
Prophylactic Mastectomy/*statistics & numerical data
Adolescent ; Adult ; Ataxia Telangiectasia Mutated Proteins/genetics ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Breast Neoplasms/diagnosis ; Breast Neoplasms/genetics ; Checkpoint Kinase 2/genetics ; Fanconi Anemia Complementation Group N Protein/genetics ; Female ; Genetic Carrier Screening/statistics & numerical data ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Guideline Adherence/standards ; Guideline Adherence/statistics & numerical data ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Heterozygote ; Humans ; Medical History Taking ; Medical Overuse/prevention & control ; Medical Overuse/statistics & numerical data ; Ovariectomy/standards ; Practice Guidelines as Topic ; Practice Patterns, Physicians'/standards ; Prophylactic Mastectomy/standards ; Young Adult
SCR Disease Name :
Breast Cancer, Familial
Czasopismo naukowe
Tytuł :
Risk of Prostate Cancer Associated With Familial and Hereditary Cancer Syndromes.
Autorzy :
Beebe-Dimmer JL; Department of Oncology, Wayne State University School of Medicine, Detroit, MI.; Barbara Ann Karmanos Cancer Institute, Detroit, MI.
Kapron AL; University of Utah, Salt Lake City, UT.
Fraser AM; University of Utah, Salt Lake City, UT.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.
Smith KR; University of Utah, Salt Lake City, UT.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.
Cooney KA; Duke University School of Medicine, Durham, NC.
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Źródło :
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2020 Jun 01; Vol. 38 (16), pp. 1807-1813. Date of Electronic Publication: 2020 Mar 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Prostatic Neoplasms/*genetics
Adult ; Age of Onset ; Aged ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/mortality ; Databases, Factual ; Female ; Genetic Predisposition to Disease ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Hereditary Breast and Ovarian Cancer Syndrome/mortality ; Heredity ; Humans ; Male ; Middle Aged ; Pedigree ; Phenotype ; Prevalence ; Prognosis ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/mortality ; Risk Assessment ; Risk Factors ; SEER Program ; Utah/epidemiology
SCR Disease Name :
Prostate cancer, familial
Czasopismo naukowe
Tytuł :
Population-based genetic testing for Women's cancer prevention.
Autorzy :
Evans O; Wolfson Institute of Preventive Medicine, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK; Department of Gynaecological Oncology, St Bartholomew's Hospital, EC1A 7BE, London, UK.
Gaba F; Wolfson Institute of Preventive Medicine, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK; Department of Gynaecological Oncology, St Bartholomew's Hospital, EC1A 7BE, London, UK.
Manchanda R; Wolfson Institute of Preventive Medicine, Barts CRUK Cancer Centre, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK; Department of Gynaecological Oncology, St Bartholomew's Hospital, EC1A 7BE, London, UK. Electronic address: .
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Źródło :
Best practice & research. Clinical obstetrics & gynaecology [Best Pract Res Clin Obstet Gynaecol] 2020 May; Vol. 65, pp. 139-153. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetics, Population*
Breast Neoplasms/*genetics
Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics
Genetic Predisposition to Disease/*ethnology
Genetic Testing/*methods
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Ovarian Neoplasms/*genetics
Breast Neoplasms/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/ethnology ; Early Detection of Cancer ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Predisposition to Disease/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/ethnology ; Humans ; Mutation ; Neoplasms ; Ovarian Neoplasms/diagnosis
Czasopismo naukowe
Tytuł :
Prognosis of BRCA1/2-negative breast cancer patients with HBOC risk factors compared with sporadic breast cancer patients without HBOC risk factors.
Autorzy :
Ryu JM; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Nam SJ; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Kim SW; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee JE; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chae BJ; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Lee SK; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Yu J; Division of Breast Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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Źródło :
Japanese journal of clinical oncology [Jpn J Clin Oncol] 2020 Feb 17; Vol. 50 (2), pp. 104-113.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
Breast Neoplasms/*mortality
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Hereditary Breast and Ovarian Cancer Syndrome/*mortality
Adult ; Aged ; Biomarkers, Tumor/genetics ; Breast Neoplasms/pathology ; Female ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Humans ; Male ; Middle Aged ; Prognosis ; Risk Factors ; Survival Analysis
Czasopismo naukowe
Tytuł :
Characterization of therapy-related acute leukemia in hereditary breast-ovarian carcinoma patients: role of BRCA1 mutation and topoisomerase II-directed therapy.
Autorzy :
Bagal B; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Kumar R; Cell and Tumor Biology Group, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Sector 22, Raintree street, Kharghar, Navi Mumbai, Maharashtra, 410210, India.
Gaur T; Cell and Tumor Biology Group, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Sector 22, Raintree street, Kharghar, Navi Mumbai, Maharashtra, 410210, India.
Talreja V; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.
Bonda A; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Patkar N; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Shetty D; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.
Kowtal P; Genome Biology Group, Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, 410210, India.
Subramanian PG; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Gupta S; Department of Medical Oncology, Tata Memorial Centre, Mumbai, 400012, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Sarin R; Genome Biology Group, Advanced Centre for Treatment, Research and Education in Cancer, Navi Mumbai, 410210, India.; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India.
Hasan SK; Adult Hemato-Lymphoid Disease Management Group, Tata Memorial Hospital, Mumbai, 400012, India. .; Cell and Tumor Biology Group, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Sector 22, Raintree street, Kharghar, Navi Mumbai, Maharashtra, 410210, India. .; Homi Bhabha National Institute (HBNI), Anushaktinagar, Mumbai, 400094, India. .
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Źródło :
Medical oncology (Northwood, London, England) [Med Oncol] 2020 Apr 10; Vol. 37 (5), pp. 48. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
BRCA1 Protein/*genetics
Carcinoma/*drug therapy
Hereditary Breast and Ovarian Cancer Syndrome/*drug therapy
Leukemia, Myeloid, Acute/*chemically induced
Topoisomerase II Inhibitors/*adverse effects
Adult ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carcinoma/genetics ; Carcinoma/pathology ; Female ; Germ-Line Mutation ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Middle Aged ; Oncogene Proteins, Fusion/genetics ; Topoisomerase II Inhibitors/therapeutic use ; Translocation, Genetic ; Treatment Outcome
Czasopismo naukowe
Tytuł :
[Hereditary breast and ovarian cancer syndrome: Diagnosis and therapeutic implications].
Autorzy :
Koual M; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France; Inserm UMR-S1124, université de Paris, centre universitaire des Saints-Pères, Paris, France.
Perkins G; Équipe labellisée Ligue-Nationale contre le cancer, centre de recherche des cordeliers, Inserm, CNRS, Sorbonne université, USPC, université Paris-Descartes, université Paris-Diderot, Paris, France; Oncogénétique, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Delanoy N; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Oncologie médicale, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Crespel C; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Oncologie médicale, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Medioni J; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Oncologie médicale, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Nguyen-Xuan HT; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Douay-Hauser N; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Blons H; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Équipe labellisée Ligue-Nationale contre le cancer, centre de recherche des cordeliers, Inserm, CNRS, Sorbonne université, USPC, université Paris-Descartes, université Paris-Diderot, Paris, France; Biochimie, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Le Frère-Belda MA; Anatomo-pathologie, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Molière D; Oncogénétique, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Achen G; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Nos C; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Balaya V; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Montero R; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France.
Laurent-Puig P; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Équipe labellisée Ligue-Nationale contre le cancer, centre de recherche des cordeliers, Inserm, CNRS, Sorbonne université, USPC, université Paris-Descartes, université Paris-Diderot, Paris, France; Oncogénétique, APHP centre, hôpital européen Georges-Pompidou, Paris, France.
Bats AS; Faculté de médecine Paris-Descartes, université de Paris, Paris, France; Chirurgie cancérologique gynécologique et du sein, APHP centre, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris, France; Équipe labellisée Ligue-Nationale contre le cancer, centre de recherche des cordeliers, Inserm, CNRS, Sorbonne université, USPC, université Paris-Descartes, université Paris-Diderot, Paris, France. Electronic address: .
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Transliterated Title :
Syndrome héréditaire de prédisposition au cancer du sein et de l’ovaire : diagnostic et implications thérapeutiques.
Źródło :
Annales de pathologie [Ann Pathol] 2020 Apr; Vol. 40 (2), pp. 70-77. Date of Electronic Publication: 2020 Feb 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hereditary Breast and Ovarian Cancer Syndrome*/diagnosis
Hereditary Breast and Ovarian Cancer Syndrome*/drug therapy
Hereditary Breast and Ovarian Cancer Syndrome*/genetics
BRCA1 Protein/analysis ; BRCA1 Protein/genetics ; BRCA2 Protein/analysis ; BRCA2 Protein/genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Predisposition to Disease ; Genetic Testing ; Humans ; Mutation ; Ovarian Neoplasms/drug therapy ; Phthalazines/therapeutic use ; Piperazines/therapeutic use ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Clinical Validity of Next-Generation Sequencing Multi-Gene Panel Testing for Detecting Pathogenic Variants in Patients With Hereditary Breast-Ovarian Cancer Syndrome.
Autorzy :
Yoo J; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Lee GD; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim JH; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Lee SN; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chae H; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Han E; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim Y; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kim M; Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Genetic Laboratory Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. .
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Źródło :
Annals of laboratory medicine [Ann Lab Med] 2020 Mar; Vol. 40 (2), pp. 148-154.
Typ publikacji :
Journal Article
MeSH Terms :
Hereditary Breast and Ovarian Cancer Syndrome/*diagnosis
High-Throughput Nucleotide Sequencing/*methods
Adult ; Aged ; Aged, 80 and over ; BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; Checkpoint Kinase 2/genetics ; Fanconi Anemia Complementation Group N Protein/genetics ; Female ; Genetic Variation ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Humans ; Middle Aged ; Pedigree ; Sequence Analysis, DNA ; Young Adult
Czasopismo naukowe
Tytuł :
Randomised trial of population-based BRCA testing in Ashkenazi Jews: long-term outcomes.
Autorzy :
Manchanda R; Wolfson Institute of Preventive Medicine, Barts Cancer Institute, Queen Mary University of London, London, UK.; Department of Gynaecological Oncology, St Bartholomew's Hospital, London, UK.; MRC Clinical Trials Unit, University College London, London, UK.
Burnell M; MRC Clinical Trials Unit, University College London, London, UK.
Gaba F; Wolfson Institute of Preventive Medicine, Barts Cancer Institute, Queen Mary University of London, London, UK.
Desai R; MRC Clinical Trials Unit, University College London, London, UK.
Wardle J; Behavioural Sciences Unit, Department of Epidemiology and Public Health, University College London, London, UK.
Gessler S; MRC Clinical Trials Unit, University College London, London, UK.
Side L; University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Sanderson S; Behavioural Sciences Unit, Department of Epidemiology and Public Health, University College London, London, UK.
Loggenberg K; North East Thames Regional Genetics Unit, Department of Clinical Genetics, Great Ormond Street Hospital, London, UK.
Brady AF; North West Thames Regional Genetics Service, Northwick Park Hospital, Harrow, UK.
Dorkins H; St Peter's College, University of Oxford, Oxford, UK.
Wallis Y; West Midlands Regional Genetics Laboratory, Birmingham Women's NHS Foundation Trust, Birmingham, UK.
Chapman C; West Midlands Regional Genetics Service, Department of Clinical Genetics, Birmingham Women's NHS Foundation Trust, Birmingham, UK.
Jacobs C; Department of Clinical Genetics, Guy's Hospital, London, UK.; University of Technology Sydney, Sydney, NSW, Australia.
Legood R; Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Beller U; Department of Gynaecology, Shaare Zedek Medical Centre, Jerusalem, Israel.
Tomlinson I; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
Menon U; MRC Clinical Trials Unit, University College London, London, UK.
Jacobs I; University of New South Wales, UNSW Sydney, Sydney, NSW, Australia.
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Źródło :
BJOG : an international journal of obstetrics and gynaecology [BJOG] 2020 Feb; Vol. 127 (3), pp. 364-375. Date of Electronic Publication: 2019 Sep 10.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Anxiety*/physiopathology
Anxiety*/prevention & control
Early Detection of Cancer*/methods
Early Detection of Cancer*/psychology
Genes, BRCA1*
Genes, BRCA2*
Hereditary Breast and Ovarian Cancer Syndrome*/diagnosis
Hereditary Breast and Ovarian Cancer Syndrome*/ethnology
Hereditary Breast and Ovarian Cancer Syndrome*/genetics
Hereditary Breast and Ovarian Cancer Syndrome*/psychology
Quality of Life*
Adult ; Female ; Genetic Predisposition to Disease/psychology ; Genetic Testing/methods ; Genetic Testing/statistics & numerical data ; Humans ; Jews/genetics ; Jews/statistics & numerical data ; London/epidemiology ; Male ; Medical History Taking/statistics & numerical data ; Uncertainty
Czasopismo naukowe
Tytuł :
Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations.
Autorzy :
Vysotskaia V; Myriad Women's Health, South San Francisco, California.
Kaseniit KE; Myriad Genetics, Salt Lake City, Utah.
Bucheit L; Myriad Women's Health, South San Francisco, California.
Ready K; Myriad Women's Health, South San Francisco, California.
Price K; Counsyl, Inc., South San Fancisco, California.
Johansen Taber K; Myriad Women's Health, South San Francisco, California.
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Źródło :
Cancer [Cancer] 2020 Feb 01; Vol. 126 (3), pp. 549-558. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Genetic Testing*
Breast Neoplasms/*diagnosis
Hereditary Breast and Ovarian Cancer Syndrome/*diagnosis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Ataxia Telangiectasia Mutated Proteins/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Cycle Proteins/genetics ; Checkpoint Kinase 2/genetics ; DNA-Binding Proteins/genetics ; Fanconi Anemia Complementation Group N Protein/genetics ; Fanconi Anemia Complementation Group Proteins/genetics ; Female ; Health Personnel ; Hereditary Breast and Ovarian Cancer Syndrome/genetics ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Nuclear Proteins/genetics ; RNA Helicases/genetics ; Risk Factors ; Young Adult
Czasopismo naukowe
Tytuł :
An immune-centric exploration of BRCA1 and BRCA2 germline mutation related breast and ovarian cancers.
Autorzy :
Przybytkowski E; Department of Computer Science and Engineering, University of Connecticut, Institute of System Genomics, Boston, MA, USA.
Davis T; Department of Computer Science and Engineering, University of Connecticut, Institute of System Genomics, Boston, MA, USA.
Hosny A; Department of Computer Science and Engineering, University of Connecticut, Institute of System Genomics, Boston, MA, USA.
Eismann J; Dana-Farber Cancer Institute, Boston, MA, USA.
Matulonis UA; Dana-Farber Cancer Institute, Boston, MA, USA.
Wulf GM; Beth Israel Deaconess Medical Center, Department of Hematology/Oncology, Harvard Medical School, Boston, MA, USA.
Nabavi S; Department of Computer Science and Engineering, University of Connecticut, Institute of System Genomics, Boston, MA, USA. .
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Źródło :
BMC cancer [BMC Cancer] 2020 Mar 12; Vol. 20 (1), pp. 197. Date of Electronic Publication: 2020 Mar 12.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Cystadenocarcinoma, Serous/*genetics
Gene Expression Profiling/*methods
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Ovarian Neoplasms/*genetics
Triple Negative Breast Neoplasms/*genetics
Cystadenocarcinoma, Serous/pathology ; Data Mining ; Female ; Genomic Instability ; Germ-Line Mutation ; Hereditary Breast and Ovarian Cancer Syndrome/pathology ; Homologous Recombination ; Humans ; Ovarian Neoplasms/pathology ; Sequence Analysis, RNA ; Triple Negative Breast Neoplasms/pathology ; Tumor Microenvironment ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Communication About Hereditary Cancers on Social Media: A Content Analysis of Tweets About Hereditary Breast and Ovarian Cancer and Lynch Syndrome.
Autorzy :
Allen CG; Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, GA, 30322, USA. .
Roberts M; The National Cancer Institute, 9609 Medical Center Drive, Rockville, MD, 20850, USA.
Andersen B; Boston University, 704 Commonwealth Avenue, Boston, MA, 02215, USA.
Khoury MJ; Office of Public Health Genomics, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA, 30329, USA.
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Źródło :
Journal of cancer education : the official journal of the American Association for Cancer Education [J Cancer Educ] 2020 Feb; Vol. 35 (1), pp. 131-137.
Typ publikacji :
Journal Article
MeSH Terms :
Consumer Health Information*
Health Communication*
Health Knowledge, Attitudes, Practice*
Colorectal Neoplasms, Hereditary Nonpolyposis/*prevention & control
Health Promotion/*methods
Hereditary Breast and Ovarian Cancer Syndrome/*prevention & control
Social Media/*statistics & numerical data
Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Female ; Genetic Predisposition to Disease ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; Humans ; Male ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Prevalence of hereditary breast and ovarian cancer (HBOC) predisposition gene mutations among 882 HBOC high-risk Chinese individuals.
Autorzy :
Shao D; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, Guangzhou, China.
Cheng S; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, Guangzhou, China.
Guo F; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, Guangzhou, China.
Zhu C; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Yuan Y; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Hu K; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, Guangzhou, China.
Wang Z; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Meng X; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Jin X; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Xiong Y; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Chai X; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Li H; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Zhang Y; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Zhang H; BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Liu J; Department of Gynecology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Ye M; BGI Genomics, BGI-Shenzhen, Shenzhen, China.; BGI-Guangzhou Medical Laboratory, BGI-Shenzhen, Guangzhou, China.
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Źródło :
Cancer science [Cancer Sci] 2020 Feb; Vol. 111 (2), pp. 647-657. Date of Electronic Publication: 2019 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Heterogeneity*
Mutation*
Asian Continental Ancestry Group/*genetics
Genetic Testing/*methods
Hereditary Breast and Ovarian Cancer Syndrome/*genetics
Adolescent ; Adult ; Aged ; Aged, 80 and over ; China ; Early Detection of Cancer ; Female ; Genetic Predisposition to Disease ; Hereditary Breast and Ovarian Cancer Syndrome/diagnosis ; High-Throughput Nucleotide Sequencing ; Humans ; Middle Aged ; Prevalence ; Sequence Analysis, DNA ; Young Adult
Czasopismo naukowe

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