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Wyszukujesz frazę ""Heterotrimeric GTP-Binding Proteins"" wg kryterium: Temat


Tytuł :
Heterotrimeric G protein signalling in plant biotic and abiotic stress response.
Autorzy :
Zhang H; School of Agriculture, Ningxia University, Yinchuan, China.
Xie P; State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China.
Xu X; School of Agriculture, Ningxia University, Yinchuan, China.; Breeding Base of State Key Laboratory of Land Degradation and Ecological Restoration of North Western China, Ningxia University, Yinchuan, China.
Xie Q; State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China.
Yu F; State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China.
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Źródło :
Plant biology (Stuttgart, Germany) [Plant Biol (Stuttg)] 2021 May; Vol. 23 Suppl 1, pp. 20-30. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biological Phenomena*
Heterotrimeric GTP-Binding Proteins*/genetics
Heterotrimeric GTP-Binding Proteins*/metabolism
Gene Expression Regulation, Plant ; Signal Transduction ; Stress, Physiological
Czasopismo naukowe
Tytuł :
A universal allosteric mechanism for G protein activation.
Autorzy :
Knight KM; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Ghosh S; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Campbell SL; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Lefevre TJ; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
Olsen RHJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Smrcka AV; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
Valentin NH; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Yin G; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Vaidehi N; Department of Computational and Quantitative Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA. Electronic address: .
Dohlman HG; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Apr 01; Vol. 81 (7), pp. 1384-1396.e6. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Guanosine Triphosphate*/chemistry
Guanosine Triphosphate*/metabolism
Heterotrimeric GTP-Binding Proteins*/chemistry
Heterotrimeric GTP-Binding Proteins*/metabolism
Molecular Dynamics Simulation*
Saccharomyces cerevisiae Proteins*/chemistry
Saccharomyces cerevisiae Proteins*/metabolism
Saccharomyces cerevisiae/*enzymology
Allosteric Regulation ; Amino Acid Motifs ; HEK293 Cells ; Humans
Czasopismo naukowe
Tytuł :
Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
Autorzy :
Zhang M; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Gui M; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Wang ZF; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Gorgulla C; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of physics, Faculty of Arts and Sciences, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Yu JJ; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Wu H; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Sun ZJ; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Klenk C; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Merklinger L; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Morstein L; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Hagn F; Bavarian NMR Center at the Department of Chemistry, Technical University of Munich, Garching, Germany.; Institute of Structural Biology, Helmholtz Center Munich, Neuherberg, Germany.
Plückthun A; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Brown A; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. .
Nasr ML; Department of Medicine, Division of Renal Medicine, Division of Engineering in Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. .
Wagner G; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Mar; Vol. 28 (3), pp. 258-267. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy*
Lipid Bilayers*/chemistry
Lipid Bilayers*/metabolism
Heterotrimeric GTP-Binding Proteins/*metabolism
Heterotrimeric GTP-Binding Proteins/*ultrastructure
Nanostructures/*chemistry
Receptors, Neurotensin/*metabolism
Receptors, Neurotensin/*ultrastructure
Allosteric Regulation ; GTP-Binding Protein alpha Subunits, Gi-Go/chemistry ; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism ; GTP-Binding Protein alpha Subunits, Gi-Go/ultrastructure ; GTP-Binding Protein beta Subunits/chemistry ; GTP-Binding Protein beta Subunits/metabolism ; GTP-Binding Protein beta Subunits/ultrastructure ; GTP-Binding Protein gamma Subunits/chemistry ; GTP-Binding Protein gamma Subunits/metabolism ; GTP-Binding Protein gamma Subunits/ultrastructure ; Guanosine Diphosphate/metabolism ; Heterotrimeric GTP-Binding Proteins/chemistry ; Humans ; Micelles ; Models, Molecular ; Neurotensin/chemistry ; Neurotensin/metabolism ; Protein Conformation ; Receptors, Neurotensin/chemistry ; Signal Transduction
Czasopismo naukowe
Tytuł :
Heterotrimeric G-protein γ subunits regulate ABA signaling in response to drought through interacting with PP2Cs and SnRK2s in mulberry (Morus alba L.).
Autorzy :
Liu C; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu, 610106, PR China.
Hu J; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Fan W; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Zhu P; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Cao B; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Zheng S; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Xia Z; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Zhu Y; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China.
Zhao A; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture and Rural Affairs, Southwest University, Chongqing, 400716, PR China. Electronic address: .
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Źródło :
Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2021 Apr; Vol. 161, pp. 210-221. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Heterotrimeric GTP-Binding Proteins*
Morus*
Abscisic Acid ; Droughts ; Gene Expression Regulation, Plant ; Signal Transduction ; Stress, Physiological
Czasopismo naukowe
Tytuł :
Optical sensors of heterotrimeric G protein signaling.
Autorzy :
Bondar A; Center for Nanobiology and Structural Biology, Institute of Microbiology of the Czech Academy of Sciences, Nove Hrady, Czech Republic.; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.; Faculty of Science, University of South Bohemia, Ceske Budejovice, Czech Republic.
Lazar J; Center for Nanobiology and Structural Biology, Institute of Microbiology of the Czech Academy of Sciences, Nove Hrady, Czech Republic.; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic.
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Źródło :
The FEBS journal [FEBS J] 2021 Apr; Vol. 288 (8), pp. 2570-2584. Date of Electronic Publication: 2020 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biosensing Techniques*
Molecular Imaging*
Heterotrimeric GTP-Binding Proteins/*genetics
Receptors, G-Protein-Coupled/*genetics
Heterotrimeric GTP-Binding Proteins/chemistry ; Humans ; Receptors, G-Protein-Coupled/chemistry ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Genome-wide identification of genes involved in heterotrimeric G-protein signaling in Tartary buckwheat (Fagopyrum tataricum) and their potential roles in regulating fruit development.
Autorzy :
Liu C; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Ye X; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Zou L; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Xiang D; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Wu Q; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Wan Y; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China.
Wu X; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China. Electronic address: .
Zhao G; Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, School of Food and Biological Engineering, Chengdu University, Chengdu 610106, PR China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Feb 28; Vol. 171, pp. 435-447. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Gene Expression Regulation, Plant*
Genes, Plant*
Genome-Wide Association Study*
Fagopyrum/*genetics
Fruit/*growth & development
Heterotrimeric GTP-Binding Proteins/*genetics
Plant Proteins/*genetics
Amino Acid Sequence ; Ananas/genetics ; Chromosome Mapping ; Chromosomes, Plant/genetics ; Conserved Sequence ; Fagopyrum/growth & development ; Fagopyrum/metabolism ; Fragaria/genetics ; Fruit/genetics ; Gene Expression Profiling ; Heterotrimeric GTP-Binding Proteins/physiology ; Lycopersicon esculentum/genetics ; Multigene Family ; Organ Specificity ; Phylogeny ; Plant Proteins/physiology ; Sequence Alignment ; Sequence Homology, Amino Acid ; Signal Transduction/genetics ; Transcription Factors/genetics ; Transcription Factors/physiology ; Zea mays/genetics
Czasopismo naukowe
Tytuł :
Isolation of Lipid Rafts by the Detergent-Based and Non-detergent-Based Methods for Localization of GPCRs with Immunoblotting and Laser Scanning Confocal Microscopy.
Autorzy :
Abdelmaseeh P; Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Tiu AC; Einstein Medical Center Philadelphia, Philadelphia, PA, USA. .; Division of Kidney Diseases & Hypertension, Department of Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA. .
Rozyyev S; Division of Kidney Diseases & Hypertension, Department of Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA.; Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, Washington, DC, USA.
Asico LD; Division of Kidney Diseases & Hypertension, Department of Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA.
Jose PA; Division of Kidney Diseases & Hypertension, Department of Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA.; Department of Pharmacology-Physiology, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA.
Villar VAM; Division of Kidney Diseases & Hypertension, Department of Medicine, School of Medicine & Health Sciences, The George Washington University, Washington, DC, USA.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2268, pp. 1-20.
Typ publikacji :
Journal Article
MeSH Terms :
Detergents/*chemistry
Heterotrimeric GTP-Binding Proteins/*metabolism
Immunoblotting/*methods
Membrane Microdomains/*chemistry
Microscopy, Confocal/*methods
Receptors, G-Protein-Coupled/*metabolism
Cell Line ; Heterotrimeric GTP-Binding Proteins/isolation & purification ; Humans ; Membrane Microdomains/metabolism ; Receptors, G-Protein-Coupled/isolation & purification ; Signal Transduction
Czasopismo naukowe
Tytuł :
Signal transduction by plant heterotrimeric G-protein.
Autorzy :
Ofoe R; Department of Biology and Biochemistry, University of Bath, Bath, UK.; West African Centre for Crop Improvement, University of Ghana, Legon, Accra, Ghana.
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Źródło :
Plant biology (Stuttgart, Germany) [Plant Biol (Stuttg)] 2021 Jan; Vol. 23 (1), pp. 3-10. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heterotrimeric GTP-Binding Proteins*/metabolism
Signal Transduction*
Plant Proteins/*metabolism
Plants/*metabolism
Czasopismo naukowe
Tytuł :
Structure of the human secretin receptor coupled to an engineered heterotrimeric G protein.
Autorzy :
Fukuhara S; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Department of Family Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Kobayashi K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Kusakizako T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Iida W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Kato M; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: .
Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Dec 17; Vol. 533 (4), pp. 861-866. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Heterotrimeric GTP-Binding Proteins/*chemistry
Receptors, G-Protein-Coupled/*chemistry
Receptors, Gastrointestinal Hormone/*chemistry
Cryoelectron Microscopy ; GTP-Binding Protein alpha Subunits, Gs/chemistry ; GTP-Binding Protein alpha Subunits, Gs/genetics ; Heterotrimeric GTP-Binding Proteins/genetics ; Humans ; Ligands ; Models, Molecular ; Protein Binding ; Protein Engineering ; Secretin/chemistry
Czasopismo naukowe
Tytuł :
A G s -RhoGEF interaction: An old G protein finds a new job.
Autorzy :
Slepak VZ; Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, Florida, USA. Electronic address: .
Pronin A; Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, Florida, USA.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Dec 11; Vol. 295 (50), pp. 16929-16930.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Heterotrimeric GTP-Binding Proteins*/metabolism
Signal Transduction*
Cytoskeleton/metabolism ; Rho Guanine Nucleotide Exchange Factors/genetics ; rho GTP-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi.
Autorzy :
Kalogriopoulos NA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
Lopez-Sanchez I; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
Lin C; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
Ngo T; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093-0747.
Midde KK; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
Roy S; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093-0747.
Aznar N; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
Murray F; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, AB24 3FX Aberdeen, United Kingdom.
Garcia-Marcos M; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118.
Kufareva I; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093-0747.
Ghassemian M; Department of Chemistry and Biochemistry, Biomolecular and Proteomics Mass Spectrometry Facility, University of California, San Diego, La Jolla, CA 92093.
Ghosh P; Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0651; .; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 17; Vol. 117 (46), pp. 28763-28774. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
GTP-Binding Protein alpha Subunits/*metabolism
Heterotrimeric GTP-Binding Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
Animals ; COS Cells ; Chlorocebus aethiops ; ErbB Receptors/metabolism ; HEK293 Cells ; HeLa Cells ; Heterotrimeric GTP-Binding Proteins/physiology ; Humans ; Phosphorylation ; Receptor Protein-Tyrosine Kinases/physiology ; Signal Transduction ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł :
Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein.
Autorzy :
Garcia-Marcos M; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
Parag-Sharma K; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
Marivin A; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
Maziarz M; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
Luebbers A; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
Nguyen LT; Department of Biochemistry, Boston University School of Medicine, Boston, United States.
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Źródło :
ELife [Elife] 2020 Sep 16; Vol. 9. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Heterotrimeric GTP-Binding Proteins*/chemistry
Heterotrimeric GTP-Binding Proteins*/genetics
Heterotrimeric GTP-Binding Proteins*/metabolism
Plant Proteins*/chemistry
Plant Proteins*/genetics
Plant Proteins*/metabolism
Recombinant Fusion Proteins*/chemistry
Recombinant Fusion Proteins*/genetics
Recombinant Fusion Proteins*/metabolism
Optogenetics/*methods
Protein Engineering/*methods
Animals ; Avena/genetics ; Escherichia coli/genetics ; Humans ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł :
GPCRsignal: webserver for analysis of the interface between G-protein-coupled receptors and their effector proteins by dynamics and mutations.
Autorzy :
Miszta P; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland.
Pasznik P; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland.
Niewieczerzał S; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland.
Jakowiecki J; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland.
Filipek S; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, 02-093 Warsaw, Poland.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 02; Vol. 49 (W1), pp. W247-W256.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Software*
Receptors, G-Protein-Coupled/*chemistry
Arrestins/chemistry ; Cryoelectron Microscopy ; Heterotrimeric GTP-Binding Proteins/chemistry ; Molecular Dynamics Simulation ; Mutation ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
Heterotrimeric G-protein, Gi1, is involved in the regulation of proliferation, neuronal migration, and dendrite morphology during cortical development in vivo.
Autorzy :
Hamada N; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.
Iwamoto I; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.
Kawamura N; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.
Nagata KI; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.; Department of Neurochemistry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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Źródło :
Journal of neurochemistry [J Neurochem] 2021 May; Vol. 157 (4), pp. 1167-1181. Date of Electronic Publication: 2020 Oct 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Cortex/*metabolism
Heterotrimeric GTP-Binding Proteins/*metabolism
Neural Stem Cells/*metabolism
Neurogenesis/*physiology
Animals ; Cell Movement/physiology ; Cell Proliferation/physiology ; Dendrites/metabolism ; Mice ; Mice, Inbred ICR ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Crosstalk between heterotrimeric G protein-coupled signaling pathways and WRKY transcription factors modulating plant responses to suboptimal micronutrient conditions.
Autorzy :
Wu TY; Temasek Life Sciences Laboratory, Singapore.
Krishnamoorthi S; Temasek Life Sciences Laboratory, Singapore.
Goh H; Temasek Life Sciences Laboratory, Singapore.
Leong R; Temasek Life Sciences Laboratory, Singapore.
Sanson AC; Temasek Life Sciences Laboratory, Singapore.; Mathematical Sciences Institute, Australian National University, Canberra, Australia.
Urano D; Temasek Life Sciences Laboratory, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore.
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Źródło :
Journal of experimental botany [J Exp Bot] 2020 May 30; Vol. 71 (10), pp. 3227-3239.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arabidopsis Proteins*/metabolism
GTP-Binding Protein beta Subunits*/genetics
GTP-Binding Protein beta Subunits*/metabolism
Heterotrimeric GTP-Binding Proteins*/genetics
Gene Expression Regulation, Plant ; Micronutrients ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.
Autorzy :
van den Bos E; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Ambrosy B; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Horsthemke M; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Walbaum S; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Bachg AC; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany.
Wettschureck N; Department of Pharmacology, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.
Innamorati G; Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.
Wilkie TM; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Hanley PJ; Institut für Molekulare Zellbiologie, Westfälische Wilhelms-Universität Münster, Münster, Germany .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 May 29; Vol. 295 (22), pp. 7726-7742. Date of Electronic Publication: 2020 Apr 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Signaling*
Chemotaxis*
Models, Biological*
Heterotrimeric GTP-Binding Proteins/*metabolism
Macrophages/*metabolism
Receptor, Anaphylatoxin C5a/*metabolism
Animals ; Heterotrimeric GTP-Binding Proteins/genetics ; Mice, Knockout ; Receptor, Anaphylatoxin C5a/genetics
Czasopismo naukowe
Tytuł :
Heterotrimeric G Proteins as Therapeutic Targets in Drug Discovery.
Autorzy :
Li J; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, P. R. China.
Ge Y; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, P. R. China.
Huang JX; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, P. R. China.
Strømgaard K; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Zhang X; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, P. R. China.
Xiong XF; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006 Guangzhou, Guangdong, P. R. China.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 May 28; Vol. 63 (10), pp. 5013-5030. Date of Electronic Publication: 2019 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Delivery Systems/*trends
Drug Discovery/*trends
Heterotrimeric GTP-Binding Proteins/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Asthma/drug therapy ; Asthma/metabolism ; Bacterial Toxins/administration & dosage ; Bacterial Toxins/metabolism ; Drug Delivery Systems/methods ; Drug Discovery/methods ; Heart Failure/drug therapy ; Heart Failure/metabolism ; Heterotrimeric GTP-Binding Proteins/antagonists & inhibitors ; Humans ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Peptides, Cyclic/administration & dosage ; Peptides, Cyclic/metabolism ; Protein Structure, Secondary ; Receptors, G-Protein-Coupled/antagonists & inhibitors ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Thrombosis/drug therapy ; Thrombosis/metabolism
Czasopismo naukowe
Tytuł :
Heterotrimeric G protein are involved in the regulation of multiple agronomic traits and stress tolerance in rice.
Autorzy :
Cui Y; Rice Research Institute of Shenyang Agricultural University, Shenyang, 110866, China.
Jiang N; Shenyang Research and Development Service Center of Modern Agriculture, Shenyang, 110866, China.
Xu Z; Rice Research Institute of Shenyang Agricultural University, Shenyang, 110866, China.
Xu Q; Rice Research Institute of Shenyang Agricultural University, Shenyang, 110866, China. .
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Źródło :
BMC plant biology [BMC Plant Biol] 2020 Feb 28; Vol. 20 (1), pp. 90. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*
Heterotrimeric GTP-Binding Proteins/*genetics
Oryza/*genetics
Plant Proteins/*genetics
Amino Acid Sequence ; Base Sequence ; Heterotrimeric GTP-Binding Proteins/chemistry ; Heterotrimeric GTP-Binding Proteins/metabolism ; Oryza/metabolism ; Phylogeny ; Plant Proteins/chemistry ; Plant Proteins/metabolism ; Sequence Alignment ; Signal Transduction
Czasopismo naukowe
Tytuł :
Probing the mutational landscape of regulators of G protein signaling proteins in cancer.
Autorzy :
DiGiacomo V; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Maziarz M; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Luebbers A; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Norris JM; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Laksono P; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Garcia-Marcos M; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA. .
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Źródło :
Science signaling [Sci Signal] 2020 Feb 04; Vol. 13 (617). Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Signal Transduction*
Heterotrimeric GTP-Binding Proteins/*genetics
Neoplasms/*genetics
RGS Proteins/*genetics
Receptors, G-Protein-Coupled/*genetics
Amino Acid Sequence ; Carcinogenesis/genetics ; HEK293 Cells ; Heterotrimeric GTP-Binding Proteins/chemistry ; Heterotrimeric GTP-Binding Proteins/metabolism ; Humans ; Models, Molecular ; Neoplasms/metabolism ; Protein Binding ; Protein Domains ; RGS Proteins/chemistry ; RGS Proteins/metabolism ; Receptors, G-Protein-Coupled/chemistry ; Receptors, G-Protein-Coupled/metabolism ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Flexible functional interactions between G-protein subunits contribute to the specificity of plant responses.
Autorzy :
Roy Choudhury S; Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.
Li M; Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.
Lee V; Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.
Nandety RS; Noble Research Institute, LLC., Ardmore, OK, 73401, USA.
Mysore KS; Noble Research Institute, LLC., Ardmore, OK, 73401, USA.
Pandey S; Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.
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Źródło :
The Plant journal : for cell and molecular biology [Plant J] 2020 Apr; Vol. 102 (2), pp. 207-221. Date of Electronic Publication: 2020 Mar 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Signal Transduction*
Stress, Physiological*
Arabidopsis/*physiology
Heterotrimeric GTP-Binding Proteins/*metabolism
Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Epistasis, Genetic ; GTP-Binding Protein alpha Subunits/genetics ; GTP-Binding Protein alpha Subunits/metabolism ; GTP-Binding Protein beta Subunits/genetics ; GTP-Binding Protein beta Subunits/metabolism ; GTP-Binding Protein gamma Subunits/genetics ; GTP-Binding Protein gamma Subunits/metabolism ; Gene Regulatory Networks ; Heterotrimeric GTP-Binding Proteins/genetics ; Loss of Function Mutation ; Mutation ; Phenotype ; Plants, Genetically Modified ; Species Specificity
Czasopismo naukowe

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