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Tytuł:
Epigenetic Age Acceleration in Frontotemporal Lobar Degeneration: A Comprehensive Analysis in the Blood and Brain.
Autorzy:
Murthy M; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.; Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.
Rizzu P; German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.
Heutink P; German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.; Alector, Inc., South San Francisco, CA 94080, USA.
Mill J; Department of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter EX4 5DW, UK.
Lashley T; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.
Bettencourt C; Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London WC1N 1PJ, UK.
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Źródło:
Cells [Cells] 2023 Jul 24; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Frontotemporal Dementia*
Frontotemporal Lobar Degeneration*/genetics
Supranuclear Palsy, Progressive*/genetics
Humans ; Brain ; Mutation/genetics ; Ubiquitin-Specific Proteases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression in astrocytes.
Autorzy:
Bowles KR; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Pugh DA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Liu Y; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Patel T; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Renton AE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Bandres-Ciga S; Laboratory of Neurogenetics, National Institute On Aging, National Institutes of Health, Bethesda, MD, USA.
Gan-Or Z; Department of Human Genetics, McGill University, Montréal, Québec, Canada.; The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montréal, Québec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montréal, Québec, Canada.
Heutink P; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Siitonen A; Institute of Clinical Medicine, Department of Neurology, University of Oulu, Oulu, Finland.; Department of Neurology and Medical Research Center, Oulu University Hospital, Oulu, Finland.
Bertelsen S; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Cherry JD; Alzheimer's Disease and CTE Center, Boston University, Boston University School of Medicine, Boston, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; VA Boston Healthcare System, 150 S. Huntington Avenue, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
Karch CM; Department of Psychiatry, Washington University in St Louis, St. Louis, MO, USA.
Frucht SJ; Department of Neurology, Fresco Institute for Parkinson's and Movement Disorders, New York University Langone, New York, NY, USA.
Kopell BH; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Neuromodulation, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter I; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Institute for Exposomic Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Park YJ; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Charney A; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Raj T; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Crary JF; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Goate AM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
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Corporate Authors:
International Parkinson’s Disease Genomics Consortium (IPDGC)
Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2022 Jul 15; Vol. 17 (1), pp. 48. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Parkinson Disease*/genetics
Parkinson Disease*/pathology
Astrocytes/pathology ; DNA Copy Number Variations/genetics ; Genetic Predisposition to Disease ; Haplotypes ; Humans ; Polymorphism, Single Nucleotide ; alpha-Synuclein/genetics ; tau Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia.
Autorzy:
Miedema SSM; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands. .
Mol MO; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
Koopmans FTW; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
Hondius DC; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
van Nierop P; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
Menden K; German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Tübingen, Germany.
de Veij Mestdagh CF; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, the Netherlands.; Alzheimer Center, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.
van Rooij J; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Ganz AB; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.; Alzheimer Center, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.
Paliukhovich I; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
Melhem S; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.
Li KW; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
Holstege H; Alzheimer Center, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.; Department of Clinical Genetics, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.
Rizzu P; German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Tübingen, Germany.
van Kesteren RE; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
van Swieten JC; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands.
Heutink P; German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Tübingen, Germany.
Smit AB; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, W&N Building, C314. De Boelelaan 1105, 1081 HV, Amsterdam, The Netherlands.
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Jul 07; Vol. 10 (1), pp. 100. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Frontotemporal Dementia*/genetics
Frontotemporal Dementia*/pathology
Pick Disease of the Brain*
Endothelial Cells/metabolism ; Humans ; Intercellular Signaling Peptides and Proteins/genetics ; Mutation/genetics ; Progranulins/genetics ; Proteomics ; tau Proteins/genetics ; tau Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference.
Autorzy:
Heinzer D; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Avar M; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Pease DP; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Dhingra A; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Yin JA; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Schaper E; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Doğançay B; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Emmenegger M; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Spinelli A; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Maggi K; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Chincisan A; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Mead S; MRC Prion Unit at UCL, Institute of Prion Diseases, London, United Kingdom.
Hornemann S; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
Heutink P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Aguzzi A; Institute of Neuropathology, University of Zurich, Zurich, Switzerland.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Oct 27; Vol. 17 (10), pp. e1010013. Date of Electronic Publication: 2021 Oct 27 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation/*physiology
PrPC Proteins/*biosynthesis
RNA-Binding Proteins/*metabolism
Cell Line ; Genome-Wide Association Study ; Humans ; RNA Interference
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening.
Autorzy:
Boussaad I; Luxembourg Centre for Systems Biomedicine, Translational Neuroscience, University of Luxembourg, Luxembourg, Luxembourg.; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg.
Cruciani G; Luxembourg Centre for Systems Biomedicine, Translational Neuroscience, University of Luxembourg, Luxembourg, Luxembourg.; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg.
Bolognin S; Developmental Biology, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg, Luxembourg.
Antony P; Luxembourg Centre for Systems Biomedicine, Translational Neuroscience, University of Luxembourg, Luxembourg, Luxembourg.; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg.
Dording CM; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg.; Transversal Translational Medicine, Luxembourg Institute of Health (LIH), Strassen, Luxembourg.
Kwon YJ; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg.; Oncology Department, Luxembourg Institute of Health (LIH), Strassen, Luxembourg.
Heutink P; German Center for Neurodegenerative Diseases (DZNE)-Tübingen &, Hertie Institute for Clinical Brain Research, Otfried Müller Strasse 23, 72076, Tübingen, Germany.
Fava E; German Center for Neurodegenerative Diseases (DZNE) - Core Research Facilities and Services - Venusberg-Campus 1, Gebäude 99, 53127, Bonn, Germany.
Schwamborn JC; Developmental Biology, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg, Luxembourg.
Krüger R; Luxembourg Centre for Systems Biomedicine, Translational Neuroscience, University of Luxembourg, Luxembourg, Luxembourg. .; Disease Modeling and Screening Platform (DMSP), Luxembourg Centre of Systems Biomedicine (Biomedicine), University of Luxembourg and Luxembourg Institute of Health (LIH), 6 Avenue du Swing, 4367, Belvaux, Luxembourg. .; Transversal Translational Medicine, Luxembourg Institute of Health (LIH), Strassen, Luxembourg. .; Parkinson Research Clinic, Centre Hospitalier de Luxembourg (CHL), Luxembourg, Luxembourg. .
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Źródło:
Scientific reports [Sci Rep] 2021 Jan 14; Vol. 11 (1), pp. 1439. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Automation, Laboratory*
Cell Culture Techniques*
Models, Biological*
Precision Medicine*
Organoids/*cytology
Drug Evaluation, Preclinical ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of shared heritability in common disorders of the brain.
Autorzy:
Anttila V; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA. .; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Bulik-Sullivan B; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Finucane HK; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Walters RK; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Bras J; UK Dementia Research Institute, University College London, London, UK.; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Duncan L; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Psychiatry and Behavioral Science, Stanford University, Stanford, California, USA.
Escott-Price V; Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, UK.; Dementia Research Institute, Cardiff University, Cardiff, UK.
Falcone GJ; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Gormley P; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Malik R; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
Patsopoulos NA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ripke S; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Charite Universitatsmedizin Berlin, Berlin, Germany.
Wei Z; Department of Computer Science, New Jersey Institute of Technology, New Jersey, USA.
Yu D; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Lee PH; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Turley P; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Grenier-Boley B; INSERM U1167 LabEx DISTALZ, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
Chouraki V; INSERM U1167 LabEx DISTALZ, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Centre Hosp. Univ Lille, Lille, France.
Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Berr C; INSERM U1061 - Neuropsychiatry: Epidemiological and Clinical Research, Montpellier, France.; University of Montpellier, Montpellier, France.; Memory Research and Resources Center, Department of Neurology, Montpellier University Hospital Gui de Chauliac, Montpellier, France.
Letenneur L; INSERM, UMR 1219, Bordeaux, France.; University of Bordeaux, Bordeaux, France.
Hannequin D; Rouen University Hospital, Rouen, France.; Inserm U1245, Rouen, France.
Amouyel P; INSERM U1167 LabEx DISTALZ, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Centre Hosp. Univ Lille, Lille, France.
Boland A; Centre National de Recherche en Génomique Humaine (CNRGH), Institut de biologie François Jacob, CEA, Evry, France.
Deleuze JF; Centre National de Recherche en Génomique Humaine (CNRGH), Institut de biologie François Jacob, CEA, Evry, France.
Duron E; Department of Gerontology, Hôpital Broca, AH-HP, Paris, France.; Hôpital Paul Brousse Université Paris Sud XI, Le Kremlin-Bicêtre, Paris, France.
Vardarajan BN; Gertrude H. Sergievsky Center and Dept of Neurology, Columbia University, New York, NY, USA.
Reitz C; Columbia University, New York, NY, USA.
Goate AM; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Huentelman MJ; Translational Genomics Research Institute, Neurogenomics Division, Phoenix, AZ, USA.
Kamboh MI; University of Pittsburgh, Pittsburgh, PA, USA.
Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Medicine, University of Washington, WA, USA.
Rogaeva E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada.
St George-Hyslop P; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada.; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Hakonarson H; Center for Applied Genomics of The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kukull WA; National Alzheimer Coordinating Center (NACC), Department of Epidemiology, University of Washington, Seattle, WA, USA.
Farrer LA; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Barnes LL; Rush Alzheimers Disease Center, Chicago, IL, USA.; Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA.; Department of Behavioral Sciences, Rush Medical College, Chicago, IL, USA.
Beach TG; Banner Sun Health Research Institute, Sun City, AZ, USA.
Demirci FY; University of Pittsburgh, Pittsburgh, PA, USA.
Head E; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
Hulette CM; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Jicha GA; College of Medicine, University of Kentucky, Lexington, KY, USA.
Kauwe JSK; Department of Biology, Brigham Young University, Provo, UT, USA.
Kaye JA; Layton Aging & Alzheimer's Disease Center, Oregon Health & Science University, Portland, OR, USA.
Leverenz JB; Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.
Levey AI; Department of Neurology, School of Medicine, Emory University, Atlanta, GA, USA.
Lieberman AP; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.
Pankratz VS; University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Poon WW; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA.
Quinn JF; Department of Neurology, Oregon Health and Science University, Portland, OR, USA.; Department of Neurology and Parkinson's Disease Research Education and Clinical Care Center (PADRECC), Portland Veterans Affairs Medical Center, Portland, OR, USA.
Saykin AJ; Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Schneider LS; Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Smith AG; Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
Sonnen JA; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; Department of Pathology, University of Washington, Seattle, WA, USA.
Stern RA; Boston University School of Medicine, Boston, MA, USA.
Van Deerlin VM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Van Eldik LJ; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.
Harold D; School of Biotechnology, Dublin City University, Glasnevin, Dublin, Ireland.
Russo G; Functional Genomics Center Zurich, ETH/UZH-Zurich, Zurich, Switzerland.
Rubinsztein DC; Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge, UK.; UK Dementia Research Institute, Cambridge, UK.
Bayer A; School of Medicine, Cardiff University, Cardiff, UK.
Tsolaki M; 1st and 3rd Departments of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece.; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece.
Proitsi P; Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Fox NC; Dementia Research Centre, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute, University College London, London, UK.
Hampel H; Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France.; Institute of Memory and Alzheimer's Disease (IM2A), Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.; Brain & Spine Institute (ICM), INSERM U 1127, CNRS UMR 7225, Paris, France.; AXA Research Fund & Sorbonne University Chair, Paris, France .
Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.
Mead S; Institute of Prion Diseases and MRC Prion Unit, University College London, London, UK.
Passmore P; Centre for Public Health, Queens University Belfast, Belfast, UK.
Morgan K; Human Genetics, School of Life Sciences, University of Nottingham, Nottingham UK.
Nöthen MM; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany.
Rossor M; Department of Neurodegeneration, UCL Institute of Neurology, London, UK.
Lupton MK; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Institute of Psychiatry Psychology and Neuroscience, Kings College London, UK.
Hoffmann P; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland.
Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg University Hospital, Erlangen, Germany.
Lawlor B; Department of Psychiatry and Global Brain Health Institute, Trinity College, Dublin, Ireland.
McQuillin A; Division of Psychiatry, Molecular Psychiatry Laboratory,University College London, London, UK.
Al-Chalabi A; Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, UK.; King's College Hospital, London, UK.
Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Ruiz A; Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain and Universitat Internacional de Catalunya, Barcelona, Spain.; Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.
Boada M; Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain and Universitat Internacional de Catalunya, Barcelona, Spain.
Seshadri S; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, USA.; Neurology and Neurogenetics Core, Framingham Heart Study, Framingham, MA, USA.; School of Medicine, Boston University, Boston, MA, USA.
Beiser A; School of Public Health, Boston University, Boston, MA, USA.; Framingham Heart Study, Framingham, MA, USA.; School of Medicine, Boston University, Boston, MA, USA.
Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA.
van der Lee SJ; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands.
De Jager PL; Center for Translational & Computational Neuroimmunology, Columbia University Medical Center, New York, NY, USA.
Geschwind DH; Neurogenetics Program, Departments of Neurology and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Center For Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA.
Riemenschneider M; Department of Psychiatry, Saarland University Hospital, Homburg, Germany.
Riedel-Heller S; Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA.
Ransmayr G; Department of Neurology II, Kepler University Clinic, Johannes Kepler University, Linz, Austria.
Hyman BT; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Cruchaga C; Washington University School of Medicine, St. Louis, MO, USA.
Alegret M; Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain and Universitat Internacional de Catalunya, Barcelona, Spain.
Winsvold B; Communication and Research Unit for Musculoskeletal Disorders (FORMI), Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway.
Palta P; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
Farh KH; Illumina Inc., San Diego, CA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Cuenca-Leon E; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Furlotte N; 23andMe Inc., Mountain View, CA, US.
Kurth T; Institute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Ligthart L; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Terwindt GM; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Freilinger T; Institute for Stroke and Dementia Research, Klinikum der Universitaet Muenchen, Munich, Germany.; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.
Ran C; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Borck G; Institute of Human Genetics, University of Ulm, Ulm, Germany.
Adams HHH; Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Wedenoja J; Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.
Buring JE; Brigham and Women's Hospital, Boston, MA.
Schürks M; Department of Neurology, University Hospital Essen, Germany.
Hrafnsdottir M; Landspitali National University Hospital, Reykjavik, Iceland.
Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Avera Institute for Human Genetics, Sioux Falls, SD, USA.
Penninx B; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
Artto V; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Kaunisto M; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Vepsäläinen S; Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland.
Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.
Kurki MI; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Hämäläinen E; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Huang H; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Huang J; Boston VA Research Institute, Boston, MA, USA.; Brigham Women's Hospital Division of Aging, Harvard Medical School, Boston, MA, USA.
Sandor C; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Webber C; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.; Dementia Research Institute, Cardiff University, Cardiff, UK.
Muller-Myhsok B; Max Planck Institute of Psychiatry, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Schreiber S; Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinic of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.
Salomaa V; National Institute for Health and Welfare, Helsinki, Finland.
Loehrer E; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Göbel H; Kiel Pain and Headache Center, Kiel, Germany.
Macaya A; Pediatric Neurology Research Group, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain.
Pozo-Rosich P; Headache Unit, Neurology Department, Hospital Vall d'Hebron, Barcelona, Spain.; Headache Research Group, VHIR, Autonomous University of Barcelona, Barcelona, Spain.
Hansen T; Danish Headache Center, Rigshospitalet Glostrup and University of Copenhagen, Copenhagen, Denmark.; Institute of Biological Psychiatry, Roskilde, Denmark.
Werge T; Institute of Biological Psychiatry, Roskilde, Denmark.; Department of Clinical Sciences, University of Copenhagen, Copenhagen, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.
Kaprio J; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.
Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
Kubisch C; Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ferrari MD; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Belin AC; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
van den Maagdenberg AMJM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Zwart JA; Division of Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway.
Boomsma D; Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands.; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Eriksson N; 23andMe Inc., Mountain View, CA, US.
Olesen J; Danish Headache Center, Rigshospitalet Glostrup and University of Copenhagen, Copenhagen, Denmark.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Nyholt DR; Statistical and Genomic Epidemiology Laboratory, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Avbersek A; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.
Baum L; Centre for Genomic Sciences, University of Hong Kong, Hong Kong.
Berkovic S; Epilepsy Research Centre, University of Melbourne, Heidelberg, Australia.
Bradfield J; Quantinuum Research LLC, San Diego, CA, USA.
Buono RJ; Cooper Medical School of Rowan University, Camden, NJ, USA.; Thomas Jefferson University Hospital, Philadelphia, PA, USA.; Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Catarino CB; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.; Epilepsy Society, Chalfont-St-Peter, Bucks, UK.
Cossette P; Centre de Recherche du Centre Hospitalier de l'Universite de Montreal and Department of Neurosciences, Université de Montréal, Montréal, Canada.
De Jonghe P; Neurogenetics Group, VIB-CMN, Antwerp, Belgium.; University of Antwerp, Antwerp, Belgium.; Department of Neurology, Antwerp University Hospital, Antwerp, Belgium.
Depondt C; Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Dlugos D; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Ferraro TN; Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, USA.; Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
French J; NYU School of Medicine, New York, NY, USA.
Hjalgrim H; Amplexa Genetics A/S, Odense, Denmark.
Jamnadas-Khoda J; Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.; Institute of Mental Health, University of Nottingham, Nottingham, UK.
Kälviäinen R; Epilepsy Center/Neurocenter, Kuopio University Hospital, Kuopio, Finland.; Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Kunz WS; Department of Epileptology, University Bonn Medical Center, Bonn, Germany.; Institute of Experimental Epileptology and Cognition Research, University Bonn Medical Center, Bonn, Germany.
Lerche H; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.
Leu C; Department of Clinical and Experimental Epilepsy, NIHR University College London Hospitals Biomedical Research Centre, UCL Institute of Neurology, London.
Lindhout D; Department of Genetics, University Medical Center Utrecht, the Netherlands.; Epilepsy Foundation in the Netherlands (SEIN), Heemstede, the Netherlands.
Lo W; Departments of Pediatrics and Neurology, Ohio State University, Columbus, OH, USA.; Nationwide Children's Hospital, Columbus, OH, USA.
Lowenstein D; Department of Neurology, University of California, San Francisco, CA, USA.
McCormack M; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Møller RS; Danish Epilepsy Centre, Filadelfia, Dianalund, Denmark.; Institute for Regional Health Services, University of Southern Denmark, Odense, Denmark.
Molloy A; Trinity College Dublin, Dublin, Ireland.
Ng PW; United Christian Hospital, Hong Kong.; Hong Kong Sanatorium and Hospital, Hong Kong.
Oliver K; Epilepsy Research Centre, University of Melbourne, Austin Health, Heidelberg, Australia.
Privitera M; Department of Neurology, University of Cincinnati, Cincinnati, OH, USA.; UC Gardner Neuroscience Institute, Cincinnati, OH, USA.
Radtke R; Department of Neurology, Duke University School of Medicine, Durham, NC, USA.
Ruppert AK; Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
Sander T; Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
Schachter S; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Schankin C; Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland.; Department of Neurology, University of Munich Hospital, Grosshadern, University of Munich, Germany.
Scheffer I; Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Victoria, Australia.; Department of Paediatrics, Royal Children's Hospital, The University of Melbourne, Melbourne, Victoria, Australia.; Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.
Schoch S; Institute of Neuropathology, Bonn University Medical School, Bonn, Germany.
Sisodiya SM; UCL Institute of Neurology, London, UK.; Chalfont Centre for Epilepsy, Bucks, UK.
Smith P; University Hospital of Wales, Cardiff, UK.
Sperling M; Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA.
Striano P; Pediatric Neurology and Muscular Diseases Unit-Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health University of Genoa, 'G. Gaslini' Institute, Genova, Italy.
Surges R; Department of Epileptology, University Hospital Bonn, Bonn, Germany.; Section of Epileptology, Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany.
Thomas GN; Institute of Applied Health Research, University of Birmingham, UK.
Visscher F; Department of Neurology, Admiraal De Ruyter Hospital, Goes, The Netherlands.
Whelan CD; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Zara F; Laboratory of Neurogenetics, G. Gaslini Institute, Genova, Italy.
Heinzen EL; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY, USA.
Marson A; University of Liverpool, Liverpool, UK.; Walton Centre NHS Foundation Trust, Liverpool, UK.
Becker F; Department of Neurology and Epileptology, University Hospital Tuebingen, Tuebingen, Germany.; Department of Neurology, University of Ulm, Ulm, Germany.
Stroink H; CWZ Hospital, Nijmegen, Netherlands.
Zimprich F; Department of Neurology, Medical University of Vienna, Austria.
Gasser T; Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Gibbs R; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Heutink P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Martinez M; INSERM U1220, IRSD, Toulouse, France.; Université Paul Sabatier, Toulouse, France.
Morris HR; UCL Institute of Neurology, London, UK.
Sharma M; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometery, University of Tubingen, Germany.
Ryten M; UCL Institute of Neurology, London, UK.
Mok KY; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.; Division of Life Science, Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China.
Pulit S; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Bevan S; University of Lincoln, Lincoln, UK.
Holliday E; Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia.
Attia J; University of Newcastle, Callaghan, Australia.; Hunter Medical Research Institute, Newcastle, Australia.
Battey T; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Neurocritical Care and Emergency Neurology, Massachusetts General Hospital, Boston, MA, USA.
Boncoraglio G; Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy.; PhD Program in Neuroscience, University Milano-Bicocca, Monza, Italy.
Thijs V; Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.; Austin Health, Heidelberg, Australia.
Chen WM; University of Virginia Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.
Mitchell B; Dept of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA.
Rothwell P; Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Sharma P; Institute of Cardiovascular Research, Royal Holloway University of London, London, UK .; Ashford & St Peters NHS Foundation Trust, Surrey, UK.
Sudlow C; University of Edinburgh, Edinburgh, UK.
Vicente A; Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal.; Biosystems and Integrative Sciences Institute - BioISI, University of Lisboa, Lisboa, Portugal.
Markus H; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Kourkoulis C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Pera J; Department of Neurology, Jagiellonian University Medical College, Kraków, Poland.
Raffeld M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Silliman S; Department of Neurology, College of Medicine-Jacksonville, University of Florida, Jacksonville, FL, USA.
Boraska Perica V; University of Split School of Medicine, Split, Croatia.
Thornton LM; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Huckins LM; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
William Rayner N; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK.
Lewis CM; MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Gratacos M; Genes and Disease Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain.
Rybakowski F; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poland.
Keski-Rahkonen A; Clinicum, Department of Public Health, University of Helsinki, Finland.
Raevuori A; Department of Adolescent Psychiatry, Helsinki University Central Hospital, Helsinki, Finland.; Clinicum, Department of Public Health, University of Helsinki, Finland.
Hudson JI; Harvard Medical School/McLean Hospital, Belmont, MA, USA.
Reichborn-Kjennerud T; Norwegian Institute of Public Health, Oslo, Norway.; University of Oslo, Oslo, Norway.
Monteleone P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno,Italy.
Karwautz A; Eating Disorders Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Mannik K; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Baker JH; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
O'Toole JK; Kartini Clinic, Portland, OR, USA.
Trace SE; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Davis OSP; MRC Integrative Epidemiology Unit and Bristol Medical School, University of Bristol, Bristol, UK.
Helder SG; Zorg op Orde BV, Leidschendam, The Netherlands.; MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Ehrlich S; Division of Psychological & Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technischen Universität Dresden, Dresden, Germany.
Herpertz-Dahlmann B; Department of Child & Adolescent Psychiatry & Psychosomatic Medicine of University Clinics, RWTH Aachen, Aachen, Germany .
Danner UN; Altrecht Eating Disorders Rintveld, Altrecht Mental Health Institute, Zeist, The Netherlands.; Faculty of Social Sciences, University of Utrecht, Utrecht, the Netherlands.
van Elburg AA; Altrecht Eating Disorders Rintveld, Altrecht Mental Health Institute, Zeist, The Netherlands.; Faculty of Social Sciences, University of Utrecht, Utrecht, the Netherlands.
Clementi M; Medical Genetics Unit, Department SDB, University of Padova, Padova, Italy.
Forzan M; UOC Genetica ed Epidemiologica Clinica Az. Ospedaliera, Padova, Italy.
Docampo E; Department of Human Genetics, CHU Sart-Tilman, University of Liège, Liège, Belgium.; Department of Rheumatology, CHU Sart-Tilman, University of Liège, Liège, Belgium.
Lissowska J; Department of Cancer Epidemiology and Prevention, Cancer Center and M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland.
Hauser J; Department of Psychiatry, University of Medical Sciences, Poznan, Poland.
Tortorella A; Department of Psychiatry, University of Perugia, Perugia, Italy.
Maj M; Department of Mental and Physical Health and Preventive Medicine, University of Campania 'luigi Vanvitelli', Naples, Italy.
Gonidakis F; Eating Disorders Unit, 1st Psychiatric Department, National and Kapodistrian University of Athens, Athens, Greece.
Tziouvas K; Aglaia Kyriakou Childrens Hospital, Athens, Greece.
Papezova H; Eating Disorders Unit, Department of Psychiatry, First Faculty of Medicine, Charles University, Prague, Czech Republic.; General University Hospital, Prague, Czech Republic.
Yilmaz Z; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wagner G; Medical University of Vienna, Austria.
Cohen-Woods S; School of Psychology, Flinders University, Adelaide, Australia.
Herms S; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland.
Julià A; Vall d'Hebron Research Institute, Barcelona, Spain.
Rabionet R; Institut de Recerca Sant Joan de Déu, Barcelona, Spain.; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain.; Department of Genetics, Microbiology & Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain.; Centre for Genomic Regulation (CRG), Barcelona, Spain.
Dick DM; Departments of Psychology and Human & Molecular Genetics, College Behavioral and Emotional Health Institute, Virginia Commonwealth University, Richmond, Virginia.
Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Broad Institute of MIT and Harvard, Cambridge, USA.
Andreassen OA; NORMENT, Div. of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Oslo University Hospital, Oslo, Norway.
Espeseth T; NORMENT, Div. of Mental Health and Addiction, University of Oslo, Oslo, Norway.; Department of Psychology, University of Oslo, Norway.; K. G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.
Lundervold AJ; Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway.; K. G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.
Steen VM; NORMENT, K.G. Jebsen Center for Psychosis Research, Department of Clinical Science, University of Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.
Pinto D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health & Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Scherer SW; McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, Canada.; The Centre for Applied Genomics, Hospital for Sick Children, Toronto, Canada.
Aschauer H; Biopsychosocial Corporation, Vienna, Austria.
Schosser A; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.; Zentren für Seelische Gesundheit, BBRZ-Med, Vienna, Austria.
Alfredsson L; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Padyukov L; Rheumatology Unit, Department of Medicine, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden.
Halmi KA; Weill Cornell Medical College, New York, New York, USA.
Mitchell J; School of Medicine, University of North Dakota, Grand Forks, ND, USA.; Neuropsychiatric Research Institute, Fargo, ND, USA.
Strober M; Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Bergen AW; BioRealm, Walnut, California, USA.; Oregon Research Institute, Eugene, OR, USA.
Kaye W; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Szatkiewicz JP; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Cormand B; Institut de Recerca Sant Joan de Déu, Barcelona, Spain.; Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain.; Department of Genetics, Microbiology & Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid, Spain.
Ramos-Quiroga JA; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Sánchez-Mora C; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Ribasés M; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Casas M; Universitat Autònoma de Barcelona, Barcelona, Spain.; Programa Corporatiu 'Neurodevelopment Disorders along Life Span', Institut Català de la Salut, Barcelona, Spain.; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Clinica Galatea y PAIMM, Mental Health Program for Impaired Physicians, Barcelona, Spain.
Hervas A; Child and Adolescent Mental Health Unit, Hospital Universitario Mútua de Terrassa, Barcelona, Spain.
Arranz MJ; Fundació Docència i Recerca Mútua Terrassa.
Haavik J; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Norway.; Division of Psychiatry, Haukeland University Hospital, Bergen, Norway.
Zayats T; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Norway.; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.
Johansson S; K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.
Williams N; Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, UK.
Dempfle A; Institute of Medical Informatics and Statistics, Kiel University, Kiel, Germany.
Rothenberger A; Child and Adolescent Psychiatry/Psychotherapy, University Medical Center, Goettingen, Germany.
Kuntsi J; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Oades RD; Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Essen, Germany.
Banaschewski T; Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Franke B; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.
Buitelaar JK; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands.; Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands.
Arias Vasquez A; Department of Psychiatry & Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Doyle AE; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Lesch KP; Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.; Department of Translational Psychiatry, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.; Division of Molecular Psychiatry, Center of Mental Health, University of Wuerzburg, Wuerzburg, Germany.
Freitag C; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Rivero O; Division of Molecular Psychiatry, Center of Mental Health, University of Wuerzburg, Wuerzburg, Germany.
Palmason H; Landspitali National University Hospital, Reykjavik, Iceland.
Romanos M; Center of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, Wuerzburg, Germany.
Langley K; School of Psychology, Cardiff University, UK.; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
Rietschel M; Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Witt SH; Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Dalsgaard S; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Hospital of Telemark, Kragerø, Norway.
Børglum AD; Department of Biomedicine and Human Genetics, Aarhus University, Aarhus, Denmark.; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Aarhus Genome Center, Aarhus, Denmark.
Waldman I; Department of Psychology, Emory University, Atlanta, GA, USA.
Wilmot B; Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA.
Molly N; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Bau CHD; Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; ADHD Outpatient Clinic, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Crosbie J; Neurosciences and Mental Health Program, Research Institute, Hospital for Sick Children, Toronto, Canada.; University of Toronto, Toronto, Canada.
Schachar R; Hospital for Sick Children, Toronto, Canada.; University of Toronto, Toronto, Canada.
Loo SK; Department of Psychiatry, University of California, Los Angeles, Los Angeles, CA, USA.
McGough JJ; Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Grevet EH; ADHD Outpatient Clinic, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.; Department of Psychiatry, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Robinson E; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Weiss LA; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Bacchelli E; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Bailey A; Department of Psychiatry, University of British Columbia, Vancouver, Canada.; Institute of Mental Health, University of British Columbia, Vancouver, Canada.
Bal V; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Battaglia A; Stella Maris Clinical Research Institute for Child and Adolescent Neuropsychiatry, Pisa, Italy.
Betancur C; Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine, Institut de Biologie Paris Seine, Paris, France.
Bolton P; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre in Mental Health Maudsley Hospital, London, UK.
Cantor R; Department of Human Genetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Celestino-Soper P; LifeOmic, Indianapolis, IN, USA.
Dawson G; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
De Rubeis S; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Duque F; Child Developmental Center, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.; University Clinic of Pediatrics, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Green A; Dept of Clinical Genetics, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.; School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
Klauck SM; Division of Molecular Genome Analysis and Division of Cancer Genome Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Leboyer M; Inserm U955, Psychiatrie Translationnelle, Créteil, France.; Faculté de Médecine, Université Paris Est, Créteil, France.; Fondation FondaMental, Créteil, France.
Levitt P; Children's Hospital Los Angeles, Los Angeles, CA, USA .; Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Maestrini E; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Mane S; Yale Center for Genome Analysis, Yale University, New Haven, CT, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
De-Luca DM; Division of Child and Adolescent Psychiatry, Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA.
Parr J; Institute of Neuroscience, Newcastle University, Newcastle, UK.; Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK.; Northumberland, Tyne & Wear NHS Foundation Trust, Northumberland, UK.
Regan R; School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.; Genomics Medicine Ireland, Dublin, Ireland.
Reichenberg A; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sandin S; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Vorstman J; Department of Psychiatry, Hospital for Sick Children and University of Toronto, Toronto, Canada.; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada.
Wassink T; Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Wijsman E; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA.
Cook E; Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.
Santangelo S; Center for Psychiatric Research, Maine Medical Center Research Institute, Portland, ME, USA.; Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA.
Delorme R; Child and Adolescent Psychiatry Department, Robert Debre Hospital, APHP, Paris, France.; Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France.
Rogé B; Centre d'Etudes et de Recherches en Psychopathologie et Psychologie de la Santé (CERPPS), Université Toulouse Jean Jaurès, Toulouse, France.; CERESA, Toulouse, France.; Institut Universitaire de France, Paris, France.
Magalhaes T; Genomics Medicine Ireland, Dublin, Ireland.; Academic Centre on Rare Diseases University College Dublin (ACoRD/UCD), Dublin, Ireland.
Arking D; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Schulze TG; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.; Human Genetics Branch, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA.
Thompson RC; Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Strohmaier J; Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; SRH University Heidelberg, Academy for Psychotherapy, Heidelberg, Germany.
Matthews K; Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK.; Advanced Interventions Service, NHS Tayside, Dundee, UK.
Melle I; NORMENT, K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Morris D; Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition and Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.
Blackwood D; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.
McIntosh A; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.
Bergen SE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Schalling M; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Jamain S; Inserm U955, Psychiatrie Translationnelle, Créteil, France.; Faculté de Médecine, Université Paris Est, Créteil, France.; Fondation FondaMental, Créteil, France.
Maaser A; Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.
Fischer SB; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.
Reinbold CS; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.
Fullerton JM; Neuroscience Research Australia, Sydney, Australia.; School of Medical Sciences, University of New South Wales, Sydney, Australia.
Guzman-Parra J; Unidad de Salud Mental, Hospital Regional Universitario de Malaga, Malaga, Spain.; Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain.
Mayoral F; Unidad de Salud Mental, Hospital Regional Universitario de Malaga, Malaga, Spain.; Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain.
Schofield PR; Neuroscience Research Australia, Sydney, Australia.; School of Medical Sciences, University of New South Wales, Sydney, Australia.
Cichon S; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
Mühleisen TW; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.; Department of Biomedicine, University of Basel, Basel, Switzerland.
Degenhardt F; Institute of Human Genetics, University of Bonn, Bonn, Germany.
Schumacher J; Institute of Human Genetics, University of Bonn, Bonn, Germany.
Bauer M; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Mitchell PB; School of Psychiatry, University of New South Wales, Sydney, Australia.; Black Dog Institute, Sydney, Australia.
Gershon ES; University of Chicago, Chicago, IL, USA.
Rice J; Washington University, St. Louis, MO, USA.
Potash JB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Zandi PP; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Craddock N; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
Ferrier IN; Institute of Neuroscience, Newcastle University, Newcastle, UK.
Alda M; Department of Psychiatry, Dalhousie University, Halifax, Canada.; National Institute of Mental Health, Klecany, Czech Republic.
Rouleau GA; Montreal Neurological Institute, McGill University, Montréal, Canada.; Department of Neurology and Neurosurgery, McGill University, Montréal, Canada.
Turecki G; Department of Psychiatry, McGill University, Montréal, Canada.
Ophoff R; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA.; UMC Utrecht, Utrecht, The Netherlands.
Pato C; SUNY Downstate Medical Center, Brooklyn, NY, USA.
Anjorin A; University College London, London, UK.
Stahl E; Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.
Leber M; Hospital for Psychiatry and Psychotherapy, Cologne, Germany.
Czerski PM; Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland.
Cruceanu C; Douglas Mental Health University Institute, McGill University, Montreal, Canada.; Department of Translational Research in Psychiatry, Max-Planck Institute of Psychiatry, Munich, Germany.
Jones IR; National Centre for Mental Health, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
Posthuma D; Department Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands.; Department Clinical Genetics, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, The Netherlands.
Andlauer TFM; Max Planck Institute of Psychiatry, Munich, Germany.; Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Forstner AJ; Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Streit F; Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Baune BT; Discipline of Psychiatry, University of Adelaide, Adelaide, Australia.
Air T; Discipline of Psychiatry, University of Adelaide, Adelaide, Australia.
Sinnamon G; Bela Menso Brain and Behaviour Centre, James Cook University, Varsity Lakes, Australia.; Bond University, Faculty of Society and Design, Robina, Australia.
Wray NR; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Australia.
MacIntyre DJ; Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Porteous D; Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.
Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Rivera M; Department of Biochemistry and Molecular Biology II, Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, Spain.; MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
Grove J; Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark.; Department of Biomedicine and Human Genetics, Aarhus University, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.
Middeldorp CM; Child Health Research Centre, University of Queensland, Brisbane, Australia.; Child and Youth Mental Health Service, Children's Health Queensland Health and Hospital Service, Brisbane, Australia.; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Hickie I; Brain and Mind Centre, University of Sydney, Sydney, Australia.
Pergadia M; Washington University School of Medicine, St. Louis, MO, USA.
Mehta D; School of Psychology and Counselling, Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Queensland, Australia.; University of Queensland, Brisbane, Australia.
Smit JH; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands.; Department of Research and Innovation, GGZ Ingeest, Specialized Mental Health Care, Amsterdam, the Netherlands.
Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
de Geus E; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands.
Dunn E; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
Li QS; Janssen Research & Development LLC, Titusville, NJ, USA.
Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany .; German Centre for Cardiovascular Research (DZHK e.V.), Partner Site Greifswald, Greifswald, Germany.
Schoevers RA; Research School of Behavioural and Cognitive Neurosciences, Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Beekman AT; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.; Department of Psychiatry GGZ INGEEST, Amsterdam, the Netherlands.
Knowles JA; Department of Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Viktorin A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Arnold P; Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada.; Departments of Psychiatry and Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada.; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada.
Barr CL; Krembil Research Institute, University Health Network, Toronto, Canada.; Hospital for Sick Children, Toronto, Canada.; University of Toronto, Toronto, Canada.
Bedoya-Berrio G; Grupo de Genética Molecular, Instituto de Biología, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín, Colombia.
Bienvenu OJ; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Brentani H; Department of Psychiatry, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil.
Burton C; Hospital for Sick Children, Toronto, Canada.
Camarena B; Depto. Farmacogenética, Instituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico.
Cappi C; Department of Psychiatry, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil.
Cath D; Department of Psychiatry, University of Groningen and University Medical Center, Groningen, the Netherlands.; Department of Specialized Trainings, GGZ Drenthe Mental Health Care Services, Assen, the Netherlands.
Cavallini M; Ospedale San Raffaele, Milano, Italy.
Cusi D; Bio4Dreams Srl, Milan, Italy.
Darrow S; University of California, San Francisco, CA, USA.
Denys D; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands.
Derks EM; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Dietrich A; University of Groningen, Groningen, the Netherlands.; Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Fernandez T; Yale University School of Medicine, New Haven, CT, USA.
Figee M; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Freimer N; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA.
Gerber G; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Grados M; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Greenberg E; Massachusetts General Hospital, Boston, MA, USA.
Hanna GL; Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Hartmann A; Centre National Maladie 'Syndrome Rare Gilles de la Tourette', Groupe Hospitalier Pitié-Salpêtrière, Paris, France.; Assistance Publique-Hôpitaux de Paris, Départment de Neurologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.; Sorbonne Universités, UPMC Université Paris 06, UMR S 1127, CNRS UMR 7225, ICM, Paris, France.
Hirschtritt ME; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Hoekstra PJ; Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Huang A; Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.; Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Huyser C; De Bascule, Amsterdam, The Netherlands.; Department of Child and Adolescent Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
Illmann C; Massachusetts General Hospital, Boston, MA, USA.
Jenike M; Harvard Medical School, Boston, MA, USA.
Kuperman S; Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Leventhal B; University of California, San Francisco, CA, USA.
Lochner C; MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, University of Cape Town, Cape Town, South Africa.
Lyon GJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Macciardi F; Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA.
Madruga-Garrido M; Sección de Neuropediatría, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.
Malaty IA; Department of Neurology, University of Florida, Gainesville, FL, USA.
Maras A; Yulius Academy, Yulius Mental Health Organization, Barendrecht, The Netherlands.
McGrath L; Department of Psychology, University of Denver, Denver, CO, USA.
Miguel EC; Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Mir P; Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Nestadt G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Nicolini H; National Institute of Genomic Medicine (INMEGEN), Ciudad de México, Mexico.; Clinical Research, Grupo Médico Carracci, Mexico City, Mexico.
Okun MS; Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, USA.; Fixel Center for Neurological Diseases, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.
Pakstis A; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Paschou P; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.
Piacentini J; Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Pittenger C; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Plessen K; Division of Adolescent and Child Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.; Child and Adolescent Mental Health Centre, Mental Health Services Capital Region Copenhagen, University of Copenhagen, Copenhagen, Denmark.
Ramensky V; Moscow Institute of Physics and Technology, Dolgoprudny, Institusky 9, Moscow, Russia.
Ramos EM; Department of Psychiatry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Reus V; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Richter MA; Frederick W. Thompson Anxiety Disorders Centre, Sunnybrook Health Sciences Centre, Toronto, Canada.; Department of Psychiatry, University of Toronto, Toronto, Canada.
Riddle MA; Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Robertson MM; Division of Neuropsychiatry, University College London, London, UK.
Roessner V; Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technischen Universität Dresden, Dresden, Germany.
Rosário M; Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, Brazil.; Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA.
Samuels JF; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Sandor P; Department of Psychiatry, University of Toronto, Toronto, Canada.; University Health Network, University of Toronto, Toronto, Canada.; Youthdale Treatment Centers, Toronto, Canada.
Stein DJ; Groote Schuur Hospital, Cape Town, South Africa.; MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, University of Cape Town, Cape Town, South Africa.
Tsetsos F; Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Van Nieuwerburgh F; Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium.
Weatherall S; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Wendland JR; Pfizer, Inc., New York, NY, USA.
Wolanczyk T; Department of Child Psychiatry, Medical University of Warsaw, Warsaw, Poland.
Worbe Y; Sorbonne Université, Faculty of Médecine, Paris, France.; Reference center for Gilles de la Tourette syndrome, Pitie-Salpetriere Hospital, Paris, France.; Department of Physiology, Saint Antoine Hospital, Paris, France.
Zai G; Department of Psychiatry, University of Toronto, Toronto, Canada.
Goes FS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
McLaughlin N; Butler Hospital, Providence, RI, USA.; Alpert Medical School of Brown University, Providence, RI, USA.
Nestadt PS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
Depienne C; Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen, Essen, Germany.; INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Paris, France.; IGBMC, CNRS UMR 7104/INSERM U964/Université de Strasbourg, Illkirch, France.
Konkashbaev A; Vanderbilt University Medical Center, Nashville, TN, USA.
Lanzagorta N; Clinical Research, Grupo Médico Carracci, Mexico City, Mexico.
Valencia-Duarte A; Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellín, Colombia.; Laboratorio de Genética Molecular, SIU, Universidad de Antioquia, Medellín, Colombia.
Bramon E; Division of Psychiatry, Molecular Psychiatry Laboratory,University College London, London, UK.
Buccola N; School of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Cahn W; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.
Cairns M; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia.; Priority Research Centre for Brain and Mental Health Research, Hunter Medical Research Institute, Newcastle, Australia.; Schizophrenia Research Institute, Sydney, Australia.
Chong SA; Institute of Mental Health, Singapore, Singapore.
Cohen D; Assistance Publique - Hopitaux de Paris, GH Pitié-Salpêtrière, Paris, France.; Sorbonne Université, CNRS UMR 7222 Institut des Systèmes Intelligents et Robotiques, Paris, France.
Crespo-Facorro B; Departments of Medicine and Psychiatry, School of Medicine University of Cantabria-IDIVAL, University Hospital Marqués de Valdecilla, Santander, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.
Crowley J; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Davidson M; Minerva Neurosciences Inc., Waltham, MA, USA.; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
DeLisi L; VA Boston Healthcare System, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Dinan T; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Psychiatry, University College Cork, Cork, Ireland.
Donohoe G; Neuroimaging, Cognition and Genomics (NICOG) Centre, School of Psychology, National University of Ireland Galway, Galway, Ireland.
Drapeau E; Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Duan J; Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Haan L; Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; Arkin, Amsterdam, the Netherlands.
Hougaard D; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Karachanak-Yankova S; Department of Medical Genetics, Medical University, Sofia, Bulgaria.
Khrunin A; Department of Molecular Bases of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.
Klovins J; Latvian Biomedical Research and Study Centre, Riga, Latvia.
Kučinskas V; Vilnius University, Vilnius, Lithuania.
Lee Chee Keong J; Institute of Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Limborska S; Department of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.
Loughland C; Hunter New England Local Health District, Newcastle, Australia.; University of Newcastle, Callaghan, Australia.
Lönnqvist J; National Institute for Health and Welfare, Helsinki, Finland.; Department of Psychiatry, University of Helsinki, Helsinki, Finland.
Maher B; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Mattheisen M; Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Wuerzburg, Wuerzburg, Germany.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.
McDonald C; Centre for Neuroimaging and Cognitive Genomics (NICOG), National University of Ireland, Galway, Galway, Ireland.; NCBES Galway Neuroscience Centre, National University of Ireland, Galway, Galway, Ireland.
Murphy KC; Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland.
Nenadic I; Philipps-Universität Marburg and Marburg University Hospital UKGM, Marburg, Germany.; Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.
van Os J; Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.; Maastricht University Medical Centre, Maastricht, the Netherlands.; Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
Pantelis C; Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne & Melbourne Health, Victoria, Australia.; Centre for Neural Engineering, Department of Electrical and Electronic Engineering, University of Melbourne, Victoria, Australia.; Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia.
Pato M; SUNY Downstate Medical Center, Brooklyn, NY, USA.
Petryshen T; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Quested D; Oxford Health NHS Foundation Trust, Oxford, UK.; Department of Psychiatry, University of Oxford, Oxford, UK.
Roussos P; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sanders AR; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, IL, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Schall U; University of Newcastle, Callaghan, Australia.
Schwab SG; Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, Australia.
Sim K; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Institute of Mental Health, Singapore, Singapore.
So HC; School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, Hong Kong.; KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.; Chinese University of Hong Kong, Hong Kong.
Stögmann E; Department of Neurology, Medical University of Vienna, Austria.
Subramaniam M; Institute of Mental Health, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Toncheva D; Department of Medical Genetics, Medical University, Sofia, Bulgaria.
Waddington J; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.
Walters J; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.
Weiser M; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Sheba Medical Center, Ramat Gan, Israel.
Cheng W; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Cloninger R; Departments of Psychiatry and Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Curtis D; UCL Genetics Institute, University College London, London, UK.; Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, London, UK.
Gejman PV; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.; Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, IL, USA.
Henskens F; School of Medicine & Public Health, University of Newcastle, Callaghan, Australia.; Priority Research Centre for Health Behaviour, University of Newcastle, Callaghan, Australia.; Hunter Medical Research Institute, Newcastle, Australia.
Mattingsdal M; NORMENT, K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Unit, Sørlandet Hospital, Kristiansand, Norway.
Oh SY; Department of Statistics and Applied Probability, University of California, Santa Barbara, CA, USA.; Computational Research Division, Lawrence Berkeley National Laboratory, University of California at Berkeley, Berkeley, CA, USA.
Scott R; University of Newcastle, Callaghan, Australia.; Hunter Medical Research Institute, Newcastle, Australia.; NSW Health Pathology, Newcastle, Australia.
Webb B; Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.
Breen G; Institute of Psychiatry, Psychology & Neuroscience, Social Genetics & Developmental Psychiatry Center, MRC, Kings College London, London, UK.; NIHR Maudsley Biomedical Research Centre, South London & Maudsley NHS Trust & King's College London, London, UK.
Churchhouse C; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Bulik CM; Departments of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Daly M; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Faraone SV; Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA.
Guerreiro R; UK Dementia Research Institute, University College London, London, UK.; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Holmans P; Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, UK.
Kendler KS; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.
Koeleman B; Division Biomedical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.
Mathews CA; Department of Psychiatry and UF Genetics Institute, University of Florida, Gainesville, FL, USA.; McKnight Brain Institute, University of Florida, Gainesville, FL, USA.
Price A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Scharf J; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Sklar P; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Williams J; Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, UK.; Dementia Research Institute, Cardiff University, Cardiff, UK.
Wood NW; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.; UCL Genetics Institute, University College London, London, UK.
Cotsapas C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Palotie A; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Smoller JW; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Sullivan P; Departments of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics and Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Rosand J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.
Corvin A; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. .; Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.
Neale BM; Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA. .; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Schott JM; Dementia Research Centre, UCL Institute of Neurology, London, UK.
Anney R; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK.
Elia J; Department of Pediatrics, Nemours A.I. duPont Hospital for Children, Wilmington, DE, USA.; Department of Psychiatry, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Grigoroiu-Serbanescu M; Alexandru Obregia Clinical Psychiatric Hospital, Biometric Psychiatric Genetics Research Unit, Bucharest, Romania.
Edenberg HJ; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Murray R; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
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Corporate Authors:
Brainstorm Consortium
Źródło:
Science (New York, N.Y.) [Science] 2018 Jun 22; Vol. 360 (6395).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Diseases/*genetics
Mental Disorders/*genetics
Brain Diseases/classification ; Brain Diseases/diagnosis ; Genetic Variation ; Genome-Wide Association Study ; Humans ; Mental Disorders/classification ; Mental Disorders/diagnosis ; Phenotype ; Quantitative Trait, Heritable ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.
Autorzy:
Baillie JK; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.; Intensive Care Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom.
Bretherick A; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Haley CS; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Clohisey S; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Gray A; Edinburgh Parallel Computing Centre, The University of Edinburgh, Edinburgh, United Kingdom.
Neyton LPA; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Barrett J; Statistical Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Stahl EA; Center for Statistical Genetics, Icahn School of Medicine at Mount Sinai, New York, United States of America.
Tenesa A; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Andersson R; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Brown JB; Department of Statistics, University of California, Berkeley, United States of America.
Faulkner GJ; Mater Research Institute, University of Queensland, University of Queensland, Brisbane, Australia.
Lizio M; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Schaefer U; Department for Infectious Disease Informatics, Public Health England, Colindale, United Kingdom.
Daub C; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Itoh M; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Japan.
Kondo N; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Lassmann T; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Kawai J; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Mole D; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Bajic VB; King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center, Thuwal, Kingdom of Saudi Arabia.
Heutink P; German Center for Neurodegenerative Diseases, Tübingen, Germany.
Rehli M; Dept. Hematology, University Hospital Regensburg, Regensburg, Germany.
Kawaji H; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, Wako, Japan.
Sandelin A; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark.
Suzuki H; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Satsangi J; Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Wells CA; Australian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia, Brisbane Australia.
Hacohen N; Broad Institute of Harvard and MIT, Cambridge, United States of America.
Freeman TC; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Hayashizaki Y; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Carninci P; RIKEN Omics Science Center, Yokohama, Japan, Division of Genomic Technologies, RIKEN Center for Life Science Technologies, Yokohama, Japan.
Forrest ARR; Harry Perkins Institute of Medical Research, and the Centre for Medical Research, University of Western Australia, QEII Medical Centre, Nedlands, Perth, Western Australia, Australia.
Hume DA; Division of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.; Mater Research Institute, University of Queensland, University of Queensland, Brisbane, Australia.
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Corporate Authors:
IIBDGC Consortium
Źródło:
PLoS computational biology [PLoS Comput Biol] 2018 Mar 01; Vol. 14 (3), pp. e1005934. Date of Electronic Publication: 2018 Mar 01 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genetic Predisposition to Disease/*genetics
Genomics/*methods
Promoter Regions, Genetic/*genetics
Crohn Disease/genetics ; Databases, Genetic ; Gene Expression Profiling ; Humans ; Transcriptome/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease.
Autorzy:
Mittal S; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Bjørnevik K; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; The Norwegian Multiple Sclerosis Competence Center, Department of Neurology, Haukeland University Hospital, Norway.
Im DS; Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Flierl A; The Parkinson's Institute and Clinical Center, Sunnyvale, CA 94085, USA.
Dong X; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Locascio JJ; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA.
Abo KM; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Long E; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA.
Jin M; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Xu B; Department of Pharmacology, University of California at Davis, Davis, CA 95616, USA.
Xiang YK; Department of Pharmacology, University of California at Davis, Davis, CA 95616, USA.
Rochet JC; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Engeland A; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; Department of Pharmacoepidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Rizzu P; German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.
Heutink P; German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany.
Bartels T; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Selkoe DJ; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Caldarone BJ; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard NeuroDiscovery Center, Harvard Medical School, Boston, MA 02115, USA.
Glicksman MA; Harvard NeuroDiscovery Center, Harvard Medical School, Boston, MA 02115, USA.
Khurana V; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA.
Schüle B; The Parkinson's Institute and Clinical Center, Sunnyvale, CA 94085, USA.
Park DS; Brain and Mind Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Riise T; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.; The Norwegian Multiple Sclerosis Competence Center, Department of Neurology, Haukeland University Hospital, Norway.
Scherzer CR; Neurogenomics Laboratory and Parkinson Personalized Medicine Program, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. .; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Department of Neurology, Brigham and Women's Hospital, Boston, MA 02115, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2017 Sep 01; Vol. 357 (6354), pp. 891-898.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Gene Expression Regulation*/drug effects
Parkinson Disease/*ethnology
Parkinson Disease/*genetics
Receptors, Adrenergic, beta-2/*metabolism
alpha-Synuclein/*genetics
Acetylation ; Adrenergic beta-1 Receptor Agonists/pharmacology ; Adrenergic beta-Antagonists/pharmacology ; Adrenergic beta-Antagonists/therapeutic use ; Albuterol/pharmacology ; Albuterol/therapeutic use ; Animals ; Cell Line, Tumor ; Enhancer Elements, Genetic ; Histones/metabolism ; Humans ; Ligands ; Mice ; Neuroprotective Agents/pharmacology ; Norway/ethnology ; Parkinson Disease/drug therapy ; Promoter Regions, Genetic ; Propranolol/pharmacology ; Propranolol/therapeutic use ; Receptors, Adrenergic, beta-2/genetics ; Risk ; Substantia Nigra/metabolism ; Transcription, Genetic/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mutation Frequency of the Major Frontotemporal Dementia Genes, MAPT, GRN and C9ORF72 in a Turkish Cohort of Dementia Patients.
Autorzy:
Guven G; Department of Genetics, Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey.
Lohmann E; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; DZNE, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Bras J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, United Kingdom.; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal.
Gibbs JR; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Gurvit H; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Bilgic B; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Hanagasi H; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Rizzu P; DZNE, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Heutink P; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; DZNE, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Emre M; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Erginel-Unaltuna N; Department of Genetics, Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey.
Just W; Institute of Human Genetics, University of Ulm, Ulm, Germany.
Hardy J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, United Kingdom.
Singleton A; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Guerreiro R; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, United Kingdom.; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, 3810-193 Aveiro, Portugal.
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Źródło:
PloS one [PLoS One] 2016 Sep 15; Vol. 11 (9), pp. e0162592. Date of Electronic Publication: 2016 Sep 15 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Mutation*
Frontotemporal Dementia/*genetics
Intercellular Signaling Peptides and Proteins/*genetics
Proteins/*genetics
tau Proteins/*genetics
Blotting, Southern ; C9orf72 Protein ; Cohort Studies ; Exome ; Female ; Humans ; Male ; Pedigree ; Polymerase Chain Reaction ; Progranulins ; Turkey
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe.
Autorzy:
Blauwendraat C; Applied Genomics for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. .
Francescatto M; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Gibbs JR; Laboratory of Neurogenetics, National Institute on Aging (NIA), Bethesda, Maryland, USA.; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Jansen IE; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Clinical Genetics, VU University Medical Center (VUmc), Amsterdam, The Netherlands.
Simón-Sánchez J; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Hernandez DG; Laboratory of Neurogenetics, National Institute on Aging (NIA), Bethesda, Maryland, USA.
Dillman AA; Laboratory of Neurogenetics, National Institute on Aging (NIA), Bethesda, Maryland, USA.
Singleton AB; Laboratory of Neurogenetics, National Institute on Aging (NIA), Bethesda, Maryland, USA.
Cookson MR; Laboratory of Neurogenetics, National Institute on Aging (NIA), Bethesda, Maryland, USA.
Rizzu P; Applied Genomics for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Heutink P; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Clinical Genetics, VU University Medical Center (VUmc), Amsterdam, The Netherlands.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
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Źródło:
Genome medicine [Genome Med] 2016 Jun 10; Vol. 8 (1), pp. 65. Date of Electronic Publication: 2016 Jun 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression*
Quantitative Trait Loci*
Frontal Lobe/*chemistry
High-Throughput Nucleotide Sequencing/*methods
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Databases, Genetic ; Female ; Genetic Variation ; Genotype ; Humans ; Male ; Middle Aged ; Promoter Regions, Genetic ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers.
Autorzy:
Rizzu P; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany. .
Blauwendraat C; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Heetveld S; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Lynes EM; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Castillo-Lizardo M; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Dhingra A; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Pyz E; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Hobert M; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, 72076, Germany.
Synofzik M; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, 72076, Germany.
Simón-Sánchez J; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, 72076, Germany.
Francescatto M; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.
Heutink P; German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller Strasse 23, Tübingen, 72076, Germany.; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, 72076, Germany.
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2016 Apr 14; Vol. 4 (1), pp. 37. Date of Electronic Publication: 2016 Apr 14.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*
Central Nervous System/*metabolism
Intercellular Signaling Peptides and Proteins/*genetics
Mutation/*genetics
Myeloid Cells/*metabolism
Proteins/*genetics
Proteins/*metabolism
tau Proteins/*genetics
Amyotrophic Lateral Sclerosis/metabolism ; Animals ; C9orf72 Protein ; Databases, Factual/standards ; Databases, Factual/statistics & numerical data ; Frontotemporal Dementia/metabolism ; Humans ; Lipopolysaccharide Receptors/metabolism ; Progranulins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.
Autorzy:
Desikan RS; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
Schork AJ; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA.
Wang Y; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; NORMENT; Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Witoelar A; NORMENT; Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Sharma M; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research University of Tubingen, Tubingen, Germany.; Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.
McEvoy LK; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
Holland D; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Brewer JB; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
Chen CH; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Thompson WK; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Harold D; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Wales, UK.
Williams J; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Wales, UK.
Owen MJ; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Wales, UK.
O'Donovan MC; Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Wales, UK.
Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, FL, USA.
Mayeux R; Department of Neurology, Taub Institute on Alzheimer's Disease and the Aging Brain, and Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.
Haines JL; Department of Molecular Physiology and Biophysics, Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, TN, USA.
Farrer LA; Departments of Medicine (Biomedical Genetics), Neurology, Ophthalmology, Biostatistics, and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Heutink P; German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Paul-Ehrlich-Straße 15, Tübingen, Germany.
Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.
Brice A; Sorbonne Université, UPMC Univ Paris 06, Paris, France.
Wood NW; UCL Genetics Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Hardy J; Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
Martinez M; INSERM UMR1043, CPTP, CHU Purpan, Toulouse, France.
Choi SH; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.
DeStefano A; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
Ikram MA; Deparment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Bis JC; Deparment of Internal Medicine, University of Washington, Seattle, WA, USA.
Smith A; Icelandic Heart Association, Kopavogur, Iceland.
Fitzpatrick AL; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Launer L; Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Aging, Washington, DC, USA.
van Duijn C; Deparment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Seshadri S; The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
Ulstein ID; Norwegian Centre for Dementia Research, Department of Old Age Psychiatry, Oslo University Hospital, Oslo, Norway.
Aarsland D; Department of Geriatric Psychiatry, Akershus University Hospital, Oslo, Norway.; Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway.; Alzheimer's Disease Research Centre, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Fladby T; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Neurology, Akershus University Hospital, Oslo, Norway.
Djurovic S; NORMENT; Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Hyman BT; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Snaedal J; Department of Geriatric Medicine, University Hospital Reykjavik, Reykjavik, Iceland.
Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland.
Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Gasser T; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research University of Tubingen, Tubingen, Germany.
Andreassen OA; NORMENT; Institute of Clinical Medicine, University of Oslo and Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
Dale AM; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA.; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
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Corporate Authors:
ADNI, ADGC, GERAD, CHARGE and IPDGC Investigators
Źródło:
Molecular psychiatry [Mol Psychiatry] 2015 Dec; Vol. 20 (12), pp. 1588-95. Date of Electronic Publication: 2015 Feb 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*genetics
Parkinson Disease/*genetics
tau Proteins/*genetics
Aged ; Aged, 80 and over ; Alleles ; Apolipoproteins E/genetics ; Brain/pathology ; Chromosomes, Human, Pair 17 ; Female ; Genetic Loci ; Genetic Pleiotropy ; Genome-Wide Association Study ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome.
Autorzy:
Kelmemi W; Laboratory of Human Genetics, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
Teeuw ME; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.; EMGO Institute for Health and Care Research, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.
Bochdanovits Z; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.
Ouburg S; Laboratory of Immunogenetics, Medical Microbiology and Infection Control, Research School V-ICI, VU University Medical Center, Amsterdam, The Netherlands.
Jonker MA; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
Alkuraya F; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Hashem M; Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Kayserili H; Medical Genetics Department, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
van Haeringen A; Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Juliana Children's Hospital, Hague, The Netherlands.
Sheridan E; Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK.; Department of Genetics, Wellcome Trust Brenner Building, St James's University Hospital, Leeds, UK.
Masri A; Division of Child Neurology, Department of Pediatrics, University of Jordan, Amman, Jordan.
Cobben JM; Department of Pediatric Genetics, AMC University Hospital, Amsterdam, The Netherlands.
Rizzu P; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Kostense PJ; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
Dommering CJ; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.
Henneman L; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.; EMGO Institute for Health and Care Research, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.
Bouhamed-Chaabouni H; Laboratory of Human Genetics, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
Heutink P; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Ten Kate LP; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.; EMGO Institute for Health and Care Research, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.
Cornel MC; Department of Clinical Genetics, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. .; EMGO Institute for Health and Care Research, VU University Medical Center, Mail BS7, D450, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands. .
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Źródło:
BMC medical genetics [BMC Med Genet] 2015 Jul 20; Vol. 16, pp. 50. Date of Electronic Publication: 2015 Jul 20.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Consanguinity*
Genes, Recessive*
Congenital Abnormalities/*genetics
Genome, Human/*genetics
Base Sequence ; Case-Control Studies ; Female ; Genotype ; Humans ; Male ; Pedigree ; Polymorphism, Single Nucleotide ; Sequence Analysis, DNA ; Statistics, Nonparametric
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson's Disease.
Autorzy:
Dijkstra AA; Department of Anatomy and Neurosciences, section Quantitative Morphology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands; Department of Medical genomics, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
Ingrassia A; Department of Anatomy and Neurosciences, section Quantitative Morphology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
de Menezes RX; Department of Epidemiology and Biostatistics, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
van Kesteren RE; Center for Neurogenomics and Cognitive Research, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
Rozemuller AJ; Department of Pathology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
Heutink P; Department of Medical genomics, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands; German Center for Neurodegenerative diseases (DZNE), Tübingen, Germany.
van de Berg WD; Department of Anatomy and Neurosciences, section Quantitative Morphology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
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Źródło:
PloS one [PLoS One] 2015 Jun 18; Vol. 10 (6), pp. e0128651. Date of Electronic Publication: 2015 Jun 18 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Axons/*physiology
Endocytosis/*physiology
Parkinson Disease/*physiopathology
Substantia Nigra/*physiopathology
Aged ; Case-Control Studies ; Disease Progression ; Eukaryotic Initiation Factor-2/physiology ; Female ; Humans ; In Situ Hybridization ; Lewy Body Disease/physiopathology ; Male ; Oligonucleotide Array Sequence Analysis ; Parkinson Disease/immunology ; Signal Transduction/physiology ; Substantia Nigra/immunology ; TOR Serine-Threonine Kinases/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CAGE-defined promoter regions of the genes implicated in Rett Syndrome.
Autorzy:
Vitezic M; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Department of Cell and Molecular Biology (CMB), Karolinska Institutet, Stockholm, Sweden. .; The Bioinformatics Center, Department of Biology and Biotech Research and Innovation Center, University of Copenhagen, Copenhagen, Denmark. .
Bertin N; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. .; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore. .
Andersson R; The Bioinformatics Center, Department of Biology and Biotech Research and Innovation Center, University of Copenhagen, Copenhagen, Denmark. .
Lipovich L; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA. .; Department of Neurology, School of Medicine, Wayne State University, Detroit, MI, USA. .
Kawaji H; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. .; RIKEN Preventive Medicine and Diagnosis Innovation Program (PMI), Wako, Japan. .
Lassmann T; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. .; Telethon Kids Institute, The University of Western Australia, Perth, Australia. .
Sandelin A; The Bioinformatics Center, Department of Biology and Biotech Research and Innovation Center, University of Copenhagen, Copenhagen, Denmark. .
Heutink P; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. peter.heutink@dzne.de.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. peter.heutink@dzne.de.; Eberhard Karls University, Tübingen, Germany. peter.heutink@dzne.de.
Goldowitz D; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Dept of Medical Genetics, University of British Columbia, Vancouver, Canada. .
Ha T; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Dept of Medical Genetics, University of British Columbia, Vancouver, Canada. .
Zhang P; Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Dept of Medical Genetics, University of British Columbia, Vancouver, Canada. .
Patrizi A; FM Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. .
Fagiolini M; FM Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. .
Forrest AR; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. .
Carninci P; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Division of Genomic Technologies (DGT), RIKEN Center for Life Science Technologies, Yokohama, Japan. .
Saxena A; Omics Science Center, RIKEN Yokohama Institute, Omics Science Center (OSC), 1-17-22 Suehiro cho, Tsurumi ku, Yokohama, Japan. .; Biomedical Research Centre at Guy's and St Thomas' Trust, Genomics Core Facility, Guy's Hospital, London, UK. .
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Corporate Authors:
FANTOM Consortium
Źródło:
BMC genomics [BMC Genomics] 2014 Dec 24; Vol. 15, pp. 1177. Date of Electronic Publication: 2014 Dec 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
Promoter Regions, Genetic/*genetics
Rett Syndrome/*genetics
Animals ; Brain/metabolism ; Brain/pathology ; Cell Line, Tumor ; CpG Islands/genetics ; Forkhead Transcription Factors/genetics ; Genomics ; Histones/genetics ; Humans ; Methyl-CpG-Binding Protein 2/genetics ; Mice ; Nerve Tissue Proteins/genetics ; Neurons/metabolism ; Protein Serine-Threonine Kinases/genetics ; Rett Syndrome/pathology ; TATA Box/genetics ; Transcription Initiation Site
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Trehalose improves human fibroblast deficits in a new CHIP-mutation related ataxia.
Autorzy:
Casarejos MJ; Department of Neurobiology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
Perucho J; Department of Neurobiology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
López-Sendón JL; Department of Neurology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
García de Yébenes J; Department of Neurology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
Bettencourt C; Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom; Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto, Portugal; Center of Research in Natural Resources (CIRN) and Department of Biology, University of the Azores, Ponta Delgada, Portugal.
Gómez A; Department of Neurobiology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
Ruiz C; Department of Neurology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
Heutink P; German Center for Neurodegenerative Diseases, Tübingen, Germany.
Rizzu P; German Center for Neurodegenerative Diseases, Tübingen, Germany.
Mena MA; Department of Neurobiology, Hospital Ramón y Cajal, Madrid, Spain; CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.
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Źródło:
PloS one [PLoS One] 2014 Sep 26; Vol. 9 (9), pp. e106931. Date of Electronic Publication: 2014 Sep 26 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Ataxia/*genetics
Ataxia/*metabolism
Fibroblasts/*drug effects
Fibroblasts/*metabolism
Trehalose/*pharmacology
Ubiquitin-Protein Ligases/*genetics
Ataxia/drug therapy ; Autophagy ; Caspase 3/metabolism ; Cell Proliferation ; Cell Survival/drug effects ; Cells, Cultured ; Free Radicals/metabolism ; Gene Expression ; Glutathione/metabolism ; Humans ; Mitochondria/metabolism ; Molecular Chaperones/metabolism ; Oligopeptides/pharmacology ; Reactive Oxygen Species/metabolism ; Trehalose/therapeutic use ; Ubiquitins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
Autorzy:
Nalls MA; 1] Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA. [2].
Pankratz N; 1] Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA. [2].
Lill CM; 1] Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany. [2] Department of Neurology, Focus Program Translational Neuroscience, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Do CB; 23andMe, Inc., Mountain View, California, USA.
Hernandez DG; 1] Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA. [2] Reta Lila Weston Institute, University College London Institute of Neurology, Queen Square, London, UK.
Saad M; 1] Department of Biostatistics, University of Washington, Seattle, Washington, USA. [2] INSERM, UMR 1043, Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France. [3] Paul Sabatier University, Toulouse, France.
DeStefano AL; 1] Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA. [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA. [3] National Heart, Lung, and Blood Institute (NHLBI) Framingham Heart Study, Framingham, Massachusetts, USA.
Kara E; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Bras J; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Sharma M; 1] Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany. [2] Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Schulte C; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Keller MF; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Arepalli S; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Letson C; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Edsall C; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Stefansson H; deCODE Genetics, Reykjavík, Iceland.
Liu X; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.
Pliner H; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Lee JH; The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.
Cheng R; The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.
Ikram MA; 1] Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands. [2] Department of Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands. [3] Department of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Ioannidis JP; Stanford Prevention Research Center, Stanford University, Stanford, California, USA.
Hadjigeorgiou GM; Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessaly, Larissa, Greece.
Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
Martinez M; 1] INSERM, UMR 1043, Centre de Physiopathologie de Toulouse-Purpan, Toulouse, France. [2] Paul Sabatier University, Toulouse, France.
Perlmutter JS; 1] Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.
Goate A; 1] Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA. [4] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.
Marder K; 1] The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA. [2] Gertrude H. Sergievsky Center, Columbia University Medical Center, New York, New York, USA. [3] Department of Neurology, Columbia University Medical Center, New York, New York, USA. [4] Department of Psychiatry, Columbia University Medical Center, New York, New York, USA.
Fiske B; The Michael J. Fox Foundation for Parkinson's Research, New York, New York, USA.
Sutherland M; Neuroscience Center, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.
Xiromerisiou G; 1] Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessaly, Larissa, Greece. [2] Department of Neurology, Papageorgiou Hospital, Thessaloniki, Greece.
Myers RH; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.
Clark LN; 1] Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA. [2] The Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.
Stefansson K; deCODE Genetics, Reykjavík, Iceland.
Hardy JA; Reta Lila Weston Institute, University College London Institute of Neurology, Queen Square, London, UK.
Heutink P; Genome Biology for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Chen H; Epidemiology Branch, National Institute of Environmental Health Sciences, US National Institutes of Health, Research Triangle, North Carolina, USA.
Wood NW; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Houlden H; Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK.
Payami H; New York State Department of Health Wadsworth Center, Albany, New York, USA.
Brice A; 1] Sorbonne Université, UPMC Université Paris 06, UM 75, INSERM U1127, Institut du Cerveau et de la Moelle, Paris, France. [2] CNRS, UMR 7225, Paris, France. [3] Pitié-Salpêtrière Hospital, Department of Genetics and Cytogenetics, Paris, France.
Scott WK; Department of Human Genetics, University of Miami School of Medicine, Miami, Florida, USA.
Gasser T; Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Bertram L; 1] Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany. [2] School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology and Medicine, London, UK.
Eriksson N; 23andMe, Inc., Mountain View, California, USA.
Foroud T; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, USA.
Pokaż więcej
Corporate Authors:
International Parkinson's Disease Genomics Consortium (IPDGC)
Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI)
23andMe
GenePD
NeuroGenetics Research Consortium (NGRC)
Hussman Institute of Human Genomics (HIHG)
Ashkenazi Jewish Dataset Investigator
Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE)
North American Brain Expression Consortium (NABEC)
United Kingdom Brain Expression Consortium (UKBEC)
Greek Parkinson's Disease Consortium
Alzheimer Genetic Analysis Group
Źródło:
Nature genetics [Nat Genet] 2014 Sep; Vol. 46 (9), pp. 989-93. Date of Electronic Publication: 2014 Jul 27.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Genetic Loci*
Parkinson Disease/*genetics
Case-Control Studies ; Genetic Predisposition to Disease ; Genome-Wide Association Study/methods ; Genotype ; Humans ; Polymorphism, Single Nucleotide ; Risk Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A promoter-level mammalian expression atlas.
Autorzy:
Forrest AR
Kawaji H
Rehli M
Baillie JK
de Hoon MJ
Haberle V
Lassmann T
Kulakovskiy IV
Lizio M
Itoh M
Andersson R
Mungall CJ
Meehan TF
Schmeier S
Bertin N
Jørgensen M
Dimont E
Arner E
Schmidl C
Schaefer U
Medvedeva YA
Plessy C
Vitezic M
Severin J
Semple C
Ishizu Y
Young RS
Francescatto M
Alam I
Albanese D
Altschuler GM
Arakawa T
Archer JA
Arner P
Babina M
Rennie S
Balwierz PJ
Beckhouse AG
Pradhan-Bhatt S
Blake JA
Blumenthal A
Bodega B
Bonetti A
Briggs J
Brombacher F
Burroughs AM
Califano A
Cannistraci CV
Carbajo D
Chen Y
Chierici M
Ciani Y
Clevers HC
Dalla E
Davis CA
Detmar M
Diehl AD
Dohi T
Drabløs F
Edge AS
Edinger M
Ekwall K
Endoh M
Enomoto H
Fagiolini M
Fairbairn L
Fang H
Farach-Carson MC
Faulkner GJ
Favorov AV
Fisher ME
Frith MC
Fujita R
Fukuda S
Furlanello C
Furino M
Furusawa J
Geijtenbeek TB
Gibson AP
Gingeras T
Goldowitz D
Gough J
Guhl S
Guler R
Gustincich S
Ha TJ
Hamaguchi M
Hara M
Harbers M
Harshbarger J
Hasegawa A
Hasegawa Y
Hashimoto T
Herlyn M
Hitchens KJ
Ho Sui SJ
Hofmann OM
Hoof I
Hori F
Huminiecki L
Iida K
Ikawa T
Jankovic BR
Jia H
Joshi A
Jurman G
Kaczkowski B
Kai C
Kaida K
Kaiho A
Kajiyama K
Kanamori-Katayama M
Kasianov AS
Kasukawa T
Katayama S
Kato S
Kawaguchi S
Kawamoto H
Kawamura YI
Kawashima T
Kempfle JS
Kenna TJ
Kere J
Khachigian LM
Kitamura T
Klinken SP
Knox AJ
Kojima M
Kojima S
Kondo N
Koseki H
Koyasu S
Krampitz S
Kubosaki A
Kwon AT
Laros JF
Lee W
Lennartsson A
Li K
Lilje B
Lipovich L
Mackay-Sim A
Manabe R
Mar JC
Marchand B
Mathelier A
Mejhert N
Meynert A
Mizuno Y
de Lima Morais DA
Morikawa H
Morimoto M
Moro K
Motakis E
Motohashi H
Mummery CL
Murata M
Nagao-Sato S
Nakachi Y
Nakahara F
Nakamura T
Nakamura Y
Nakazato K
van Nimwegen E
Ninomiya N
Nishiyori H
Noma S
Noma S
Noazaki T
Ogishima S
Ohkura N
Ohimiya H
Ohno H
Ohshima M
Okada-Hatakeyama M
Okazaki Y
Orlando V
Ovchinnikov DA
Pain A
Passier R
Patrikakis M
Persson H
Piazza S
Prendergast JG
Rackham OJ
Ramilowski JA
Rashid M
Ravasi T
Rizzu P
Roncador M
Roy S
Rye MB
Saijyo E
Sajantila A
Saka A
Sakaguchi S
Sakai M
Sato H
Savvi S
Saxena A
Schneider C
Schultes EA
Schulze-Tanzil GG
Schwegmann A
Sengstag T
Sheng G
Shimoji H
Shimoni Y
Shin JW
Simon C
Sugiyama D
Sugiyama T
Suzuki M
Suzuki N
Swoboda RK
't Hoen PA
Tagami M
Takahashi N
Takai J
Tanaka H
Tatsukawa H
Tatum Z
Thompson M
Toyodo H
Toyoda T
Valen E
van de Wetering M
van den Berg LM
Verado R
Vijayan D
Vorontsov IE
Wasserman WW
Watanabe S
Wells CA
Winteringham LN
Wolvetang E
Wood EJ
Yamaguchi Y
Yamamoto M
Yoneda M
Yonekura Y
Yoshida S
Zabierowski SE
Zhang PG
Zhao X
Zucchelli S
Summers KM
Suzuki H
Daub CO
Kawai J
Heutink P
Hide W
Freeman TC
Lenhard B
Bajic VB
Taylor MS
Makeev VJ
Sandelin A
Hume DA
Carninci P
Hayashizaki Y
Pokaż więcej
Corporate Authors:
FANTOM Consortium and the RIKEN PMI and CLST (DGT)
Źródło:
Nature [Nature] 2014 Mar 27; Vol. 507 (7493), pp. 462-70.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atlases as Topic*
Molecular Sequence Annotation*
Promoter Regions, Genetic/*genetics
Transcriptome/*genetics
Animals ; Cell Line ; Cells, Cultured ; Cluster Analysis ; Conserved Sequence/genetics ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genes, Essential/genetics ; Genome/genetics ; Humans ; Mice ; Open Reading Frames/genetics ; Organ Specificity ; RNA, Messenger/analysis ; RNA, Messenger/genetics ; Transcription Factors/metabolism ; Transcription Initiation Site ; Transcription, Genetic/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
An atlas of active enhancers across human cell types and tissues.
Autorzy:
Andersson R; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Gebhard C; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Miguel-Escalada I; School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Hoof I; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Bornholdt J; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Boyd M; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Chen Y; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Zhao X; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.
Schmidl C; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Suzuki T; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Ntini E; Centre for mRNP Biogenesis and Metabolism, Department of Molecular Biology and Genetics, C.F. Møllers Alle 3, Bldg. 1130, DK-8000 Aarhus, Denmark.
Arner E; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Valen E; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.; Department of Molecular and Cellular Biology, Harvard University, USA.
Li K; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Schwarzfischer L; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Glatz D; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Raithel J; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Lilje B; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Rapin N; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.; The Finsen Laboratory, Rigshospitalet and Danish Stem Cell Centre (DanStem), University of Copenhagen, Ole Maaloes Vej 5, DK-2200, Denmark.
Bagger FO; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.; The Finsen Laboratory, Rigshospitalet and Danish Stem Cell Centre (DanStem), University of Copenhagen, Ole Maaloes Vej 5, DK-2200, Denmark.
Jørgensen M; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Andersen PR; Centre for mRNP Biogenesis and Metabolism, Department of Molecular Biology and Genetics, C.F. Møllers Alle 3, Bldg. 1130, DK-8000 Aarhus, Denmark.
Bertin N; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Rackham O; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Burroughs AM; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Baillie JK; Roslin Institute, Edinburgh University, Easter Bush, Midlothian, EH25 9RG Scotland, UK.
Ishizu Y; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Shimizu Y; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Furuhata E; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Maeda S; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Negishi Y; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Mungall CJ; Genomics Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road MS 64-121, Berkeley, CA 94720, USA.
Meehan TF; EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD.
Lassmann T; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Itoh M; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Kawaji H; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Kondo N; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Kawai J; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Lennartsson A; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Stockholm, Sweden.
Daub CO; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; Department of Biosciences and Nutrition, Karolinska Institutet, 14183 Huddinge, Stockholm, Sweden.
Heutink P; Department of Clinical Genetics, VU University Medical Center, van der Boechorststraat 7, 1081 BT Amsterdam, Netherlands.
Hume DA; Roslin Institute, Edinburgh University, Easter Bush, Midlothian, EH25 9RG Scotland, UK.
Jensen TH; Centre for mRNP Biogenesis and Metabolism, Department of Molecular Biology and Genetics, C.F. Møllers Alle 3, Bldg. 1130, DK-8000 Aarhus, Denmark.
Suzuki H; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Hayashizaki Y; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Preventive Medicine and Diagnosis Innovation Program, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Müller F; School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Forrest ARR; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Carninci P; RIKEN OMICS Science Centre, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.; RIKEN Center for Life Science Technologies (Division of Genomic Technologies), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan.
Rehli M; Department of Internal Medicine III, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.
Sandelin A; The Bioinformatics Centre, Department of Biology & Biotech Research and Innovation Centre, University of Copenhagen, Ole Maaloes Vej 5, DK-2200 Copenhagen, Denmark.
Pokaż więcej
Źródło:
Nature [Nature] 2014 Mar 27; Vol. 507 (7493), pp. 455-461.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Atlases as Topic*
Molecular Sequence Annotation*
Organ Specificity*
Enhancer Elements, Genetic/*genetics
Gene Expression Regulation/*genetics
Cell Line ; Cells, Cultured ; Cluster Analysis ; Genetic Predisposition to Disease/genetics ; HeLa Cells ; Humans ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/genetics ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Transcription Initiation Site ; Transcription Initiation, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Accurate prediction of a minimal region around a genetic association signal that contains the causal variant.
Autorzy:
Bochdanovits Z; Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Simón-Sánchez J; Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Jonker M; Section Stochastics, Department of Mathematics, Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
Hoogendijk WJ; 1] Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands [2] Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands.
van der Vaart A; Section Stochastics, Department of Mathematics, Faculty of Sciences, Vrije Universiteit, Amsterdam, The Netherlands.
Heutink P; Department of Clinical Genetics, VU University Medical Center, Amsterdam, The Netherlands.
Pokaż więcej
Źródło:
European journal of human genetics : EJHG [Eur J Hum Genet] 2014 Feb; Vol. 22 (2), pp. 238-42. Date of Electronic Publication: 2013 Jun 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Genetic*
Genome-Wide Association Study/*methods
Apolipoproteins E/genetics ; Gene Frequency ; Genetic Predisposition to Disease ; Humans ; Linkage Disequilibrium ; Parkinson Disease/genetics ; Polymorphism, Single Nucleotide ; alpha-Synuclein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 72

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