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Wyszukujesz frazę ""Hickman, James J."" wg kryterium: Autor


Tytuł :
Physiological Aβ Concentrations Produce a More Biomimetic Representation of the Alzheimer's Disease Phenotype in iPSC Derived Human Neurons.
Autorzy :
Berry BJ; NanoScience Technology Center , University of Central Florida , 12424 Research Parkway, Suite 400 , Orlando , Florida 32826 United States.
Smith AST; NanoScience Technology Center , University of Central Florida , 12424 Research Parkway, Suite 400 , Orlando , Florida 32826 United States.
Long CJ; NanoScience Technology Center , University of Central Florida , 12424 Research Parkway, Suite 400 , Orlando , Florida 32826 United States.
Martin CC; NanoScience Technology Center , University of Central Florida , 12424 Research Parkway, Suite 400 , Orlando , Florida 32826 United States.
Hickman JJ; NanoScience Technology Center , University of Central Florida , 12424 Research Parkway, Suite 400 , Orlando , Florida 32826 United States.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2018 Jul 18; Vol. 9 (7), pp. 1693-1701. Date of Electronic Publication: 2018 May 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Alzheimer Disease/*metabolism
Amyloid beta-Peptides/*metabolism
Induced Pluripotent Stem Cells/*metabolism
Neurons/*metabolism
Alzheimer Disease/pathology ; Cell Survival/physiology ; Humans ; Induced Pluripotent Stem Cells/pathology ; Membrane Potentials/physiology ; Neurons/pathology ; Patch-Clamp Techniques ; tau Proteins/metabolism
Czasopismo naukowe
Tytuł :
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.
Autorzy :
Oleaga C; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Bernabini C; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Smith AS; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Srinivasan B; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Jackson M; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
McLamb W; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Platt V; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Bridges R; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Cai Y; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Santhanam N; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Berry B; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Najjar S; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Akanda N; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Guo X; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Martin C; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Ekman G; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
Esch MB; Department of Biomedical Engineering, Cornell University, 115 and 305 Weill Hall, Ithaca, NY 14853.
Langer J; L'Oreal Research and Innovation, Clark, NJ, 07666/ Aulnay sous Bois, France, 93600.
Ouedraogo G; L'Oreal Research and Innovation, Aulnay sous Bois, France.
Cotovio J; L'Oreal Research and Innovation, Aulnay sous Bois, France.
Breton L; L'Oreal Research and Innovation, Aulnay sous Bois, France.
Shuler ML; Department of Biomedical Engineering, Cornell University, 115 and 305 Weill Hall, Ithaca, NY 14853.
Hickman JJ; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway Suite 400, Orlando, FL 32828.
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Źródło :
Scientific reports [Sci Rep] 2016 Feb 03; Vol. 6, pp. 20030. Date of Electronic Publication: 2016 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Evaluation, Preclinical/*methods
Liver/*drug effects
Muscle Fibers, Skeletal/*drug effects
Myocytes, Cardiac/*drug effects
Neurons/*drug effects
Cell Line ; Cells, Cultured ; Coculture Techniques ; Culture Media, Serum-Free ; Hep G2 Cells ; Humans ; Induced Pluripotent Stem Cells ; Lab-On-A-Chip Devices ; Liver/cytology ; Models, Biological ; Muscle Fibers, Skeletal/cytology ; Myocytes, Cardiac/cytology ; Neurons/cytology
Czasopismo naukowe
Tytuł :
Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems.
Autorzy :
Berry BJ; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Akanda N; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Smith AS; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Long CJ; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Schnepper MT; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Guo X; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
Hickman JJ; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2015 Nov-Dec; Vol. 31 (6), pp. 1613-22. Date of Electronic Publication: 2015 Sep 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Culture Techniques/*methods
Induced Pluripotent Stem Cells/*cytology
Induced Pluripotent Stem Cells/*physiology
Neurons/*cytology
Neurons/*physiology
Cell Survival ; Cells, Cultured ; Humans ; Patch-Clamp Techniques
Czasopismo naukowe
Tytuł :
Toward in vitro models of brain structure and function.
Autorzy :
Shuler ML; Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853; and .
Hickman JJ; NanoScience Technology Center, University of Central Florida, Orlando, FL 32826.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2014 Sep 23; Vol. 111 (38), pp. 13682-3. Date of Electronic Publication: 2014 Sep 05.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Cerebral Cortex/*metabolism
Neurons/*metabolism
Tissue Engineering/*methods
Animals
Czasopismo naukowe
Tytuł :
Synaptic connectivity in engineered neuronal networks.
Autorzy :
Molnar P; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL, 32826, USA, .
Kang JF
Bhargava N
Das M
Hickman JJ
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2014; Vol. 1183, pp. 243-52.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Nerve Net*
Synaptic Transmission*
Cell Culture Techniques/*methods
Neurons/*cytology
Animals ; Cell Culture Techniques/instrumentation ; Cells, Cultured ; Hippocampus/cytology ; Neuronal Plasticity ; Patch-Clamp Techniques/methods ; Rats ; Surface Properties ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Two cell circuits of oriented adult hippocampal neurons on self-assembled monolayers for use in the study of neuronal communication in a defined system.
Autorzy :
Edwards D; Nanoscience Technology Center, University of Central Florida , 12424 United States Research Parkway, Suite 400, Orlando, Florida 32826, United States.
Stancescu M
Molnar P
Hickman JJ
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2013 Aug 21; Vol. 4 (8), pp. 1174-82. Date of Electronic Publication: 2013 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hippocampus/*physiology
Neurogenesis/*physiology
Neurons/*physiology
Synaptic Transmission/*physiology
Animals ; Cell Culture Techniques/methods ; Cell Polarity ; Cells, Cultured ; Membrane Potentials/physiology ; Rats
Czasopismo naukowe
Tytuł :
Coexpression of glutamate vesicular transporter (VGLUT1) and choline acetyltransferase (ChAT) proteins in fetal rat hippocampal neurons in culture.
Autorzy :
Bhargava N; NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, FL 32826, USA.
Das M
Edwards D
Stancescu M
Kang JF
Hickman JJ
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Źródło :
In vitro cellular & developmental biology. Animal [In Vitro Cell Dev Biol Anim] 2010 Sep; Vol. 46 (8), pp. 685-92. Date of Electronic Publication: 2010 Jul 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Choline O-Acetyltransferase/*metabolism
Hippocampus/*embryology
Neurons/*metabolism
Vesicular Glutamate Transport Protein 1/*metabolism
Animals ; Cells, Cultured ; Choline O-Acetyltransferase/analysis ; Female ; Fetus ; Hippocampus/metabolism ; Rats ; Receptors, GABA/analysis ; Vesicular Glutamate Transport Protein 1/analysis
Czasopismo naukowe
Tytuł :
Addition of glutamate to serum-free culture promotes recovery of electrical activity in adult hippocampal neurons in vitro.
Autorzy :
Edwards D; NanoScience Technology Center, Orlando, FL 32826, USA.
Das M
Molnar P
Hickman JJ
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2010 Jul 15; Vol. 190 (2), pp. 155-63. Date of Electronic Publication: 2010 May 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Culture Techniques/*methods
Glutamic Acid/*metabolism
Hippocampus/*physiology
Neurons/*physiology
Aging ; Animals ; Cell Adhesion ; Cell Survival ; Culture Media, Serum-Free ; Extracellular Space/metabolism ; Glass ; Immunohistochemistry ; Membrane Potentials/physiology ; Nerve Regeneration ; Patch-Clamp Techniques ; Rats ; Rats, Sprague-Dawley ; Time Factors
Czasopismo naukowe
Tytuł :
A defined long-term in vitro tissue engineered model of neuromuscular junctions.
Autorzy :
Das M; Hybrid Systems Lab, NanoScience Technology Center, Suite 402, 12424 Research Parkway, University of Central Florida, Orlando, FL 32826, USA.
Rumsey JW
Bhargava N
Stancescu M
Hickman JJ
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Źródło :
Biomaterials [Biomaterials] 2010 Jun; Vol. 31 (18), pp. 4880-8. Date of Electronic Publication: 2010 Mar 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Tissue Engineering*
Muscle Fibers, Skeletal/*cytology
Neuromuscular Junction/*metabolism
Neurons/*cytology
Animals ; Cells, Cultured ; Coculture Techniques ; Intercellular Signaling Peptides and Proteins/metabolism ; Models, Biological ; Muscle Fibers, Skeletal/metabolism ; Myosin Heavy Chains/metabolism ; Neuromuscular Junction/ultrastructure ; Neurons/metabolism ; Rats ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Electrophysiological characterization of embryonic hippocampal neurons cultured in a 3D collagen hydrogel.
Autorzy :
Xu T; Department of Bioengineering, Clemson University, SC 29634, USA.
Molnar P
Gregory C
Das M
Boland T
Hickman JJ
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Źródło :
Biomaterials [Biomaterials] 2009 Sep; Vol. 30 (26), pp. 4377-83. Date of Electronic Publication: 2009 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Collagen/*pharmacology
Electrophysiological Phenomena/*drug effects
Embryo, Mammalian/*cytology
Hippocampus/*cytology
Hippocampus/*embryology
Hydrogel, Polyethylene Glycol Dimethacrylate/*pharmacology
Neurons/*physiology
Animals ; Cell Shape/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Microscopy, Confocal ; Models, Biological ; Neurons/cytology ; Neurons/drug effects ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system.
Autorzy :
Varghese K; NanoScience Technology Center, University of Central Florida, 12424 Research parkway, Suite# 400, Orlando, FL 32826, USA.
Das M
Bhargava N
Stancescu M
Molnar P
Kindy MS
Hickman JJ
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Źródło :
Journal of neuroscience methods [J Neurosci Methods] 2009 Feb 15; Vol. 177 (1), pp. 51-9. Date of Electronic Publication: 2008 Oct 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Culture Techniques/*methods
Hippophae/*cytology
Neurons/*physiology
Regeneration/*physiology
Animals ; Cell Survival ; Cells, Cultured ; Culture Media/pharmacology ; Electric Stimulation/methods ; Female ; Membrane Potentials/drug effects ; Membrane Potentials/physiology ; Mice ; Nerve Tissue Proteins/metabolism ; Neurons/drug effects ; Patch-Clamp Techniques ; Time Factors
Czasopismo naukowe
Tytuł :
Temporal neurotransmitter conditioning restores the functional activity of adult spinal cord neurons in long-term culture.
Autorzy :
Das M; NanoScience Technology Center, University of Central Florida, Orlando, FL 32826, USA.
Bhargava N
Bhalkikar A
Kang JF
Hickman JJ
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Źródło :
Experimental neurology [Exp Neurol] 2008 Jan; Vol. 209 (1), pp. 171-80. Date of Electronic Publication: 2007 Sep 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neurons/*physiology
Neurotransmitter Agents/*pharmacology
Spinal Cord/*cytology
Spinal Cord/*physiology
Acetylcholine/pharmacology ; Action Potentials/drug effects ; Animals ; Cells, Cultured ; Ciliary Neurotrophic Factor/pharmacology ; Electrophysiology ; Glutamic Acid/pharmacology ; Immunohistochemistry ; Motor Neurons/drug effects ; Nerve Growth Factors/pharmacology ; Nerve Regeneration/drug effects ; Neurons/drug effects ; Patch-Clamp Techniques ; Rats ; Serotonin/pharmacology ; Spinal Cord/drug effects ; Synapses/drug effects ; Vascular Endothelial Growth Factor A/pharmacology
Czasopismo naukowe
Tytuł :
Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons.
Autorzy :
Das M; NanoScience Technology Center, 12424 Research Parkway, Suite 400, University of Central Florida, Orlando, FL 32826, USA.
Patil S
Bhargava N
Kang JF
Riedel LM
Seal S
Hickman JJ
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Źródło :
Biomaterials [Biomaterials] 2007 Apr; Vol. 28 (10), pp. 1918-25. Date of Electronic Publication: 2007 Jan 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerium/*administration & dosage
Nanoparticles/*administration & dosage
Nerve Regeneration/*drug effects
Neurons/*cytology
Neurons/*drug effects
Neuroprotective Agents/*administration & dosage
Animals ; Catalysis ; Cell Survival/drug effects ; Cells, Cultured ; Cerium/chemistry ; Chemistry, Pharmaceutical/methods ; Nanoparticles/chemistry ; Nanoparticles/ultrastructure ; Neuroprotective Agents/chemistry ; Particle Size ; Rats
Czasopismo naukowe
Tytuł :
Toxin detection based on action potential shape analysis using a realistic mathematical model of differentiated NG108-15 cells.
Autorzy :
Mohan DK; Department of Electrical Engineering, Clemson University, Clemson, SC 29634, USA.
Molnar P
Hickman JJ
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Źródło :
Biosensors & bioelectronics [Biosens Bioelectron] 2006 Mar 15; Vol. 21 (9), pp. 1804-11. Date of Electronic Publication: 2006 Feb 03.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Action Potentials/*drug effects
Action Potentials/*physiology
Biological Assay/*methods
Neurons/*drug effects
Neurons/*physiology
Neurotoxins/*administration & dosage
Neurotoxins/*analysis
Animals ; Biological Assay/instrumentation ; Cell Differentiation ; Cell Line ; Computer Simulation ; Dose-Response Relationship, Drug ; Environmental Pollutants/analysis ; Mice ; Models, Neurological ; Neurons/cytology ; Patch-Clamp Techniques/instrumentation ; Patch-Clamp Techniques/methods ; Rats
Czasopismo naukowe
Tytuł :
Adult rat spinal cord culture on an organosilane surface in a novel serum-free medium.
Autorzy :
DAS M; Nanoscience Technology Center, University of Central Florida, Orlando, Florida 32826, USA.
Bhargava N
Gregory C
Riedel L
Molnar P
Hickman JJ
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Źródło :
In vitro cellular & developmental biology. Animal [In Vitro Cell Dev Biol Anim] 2005 Nov-Dec; Vol. 41 (10), pp. 343-8.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Culture Techniques/*methods
Culture Media/*chemistry
Neurons/*cytology
Silanes/*chemistry
Spinal Cord/*cytology
Animals ; Cells, Cultured ; Electrophysiology ; Growth Substances/chemistry ; Immunohistochemistry ; Rats
Czasopismo naukowe
Tytuł :
A New Target for Amyloid Beta Toxicity Validated by Standard and High-Throughput Electrophysiology.
Autorzy :
Varghese, Kucku
Molnar, Peter
Das, Mainak
Bhargava, Neelima
Lambert, Stephen
Kindy, Mark S.
Hickman, James J.
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Temat :
GENERAL practitioners
NEURONS
NEURODEGENERATION
DRUG development
DEATH (Biology)
PRESENILE dementia
ALZHEIMER'S disease
CELL death
APOPTOSIS
Źródło :
PLoS ONE; 2010, Vol. 5 Issue 1, p1-8, 8p, 1 Color Photograph, 6 Graphs
Czasopismo naukowe

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