Temat: "High-Throughput Nucleotide Sequencing" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: Development of a fully automated high throughput PCR for the detection of SARS-CoV-2: The need for speed.
Autorzy :: Mayer FJ; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Ratzinger F; Ihr Labor, Medical Diagnostic Laboratories , Vienna, Austria.
Schmidt RLJ; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Greiner G; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Landt O; Tib-Molbiol , Berlin, Germany.
Am Ende A; Tib-Molbiol , Berlin, Germany.
Corman VM; Charité - Universitätsmedizin Berlin Institute of Virology, Berlin, Germany and German Centre for Infection Research (DZIF) , Berlin, Germany.
Perkmann-Nagele N; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Watkins-Riedel T; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Petermann D; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.
Abadir K; QIAGEN GmbH , Vienna, Austria.
Zweimüller-Mayer J; QIAGEN GmbH , Vienna, Austria.
Strassl R; Divison of Clinical Virology, Department of Laboratory Medicine, Medical University of Vienna , Vienna, Austria.; Pokaż więcej
Źródło :: Virulence [Virulence] 2020 Dec; Vol. 11 (1), pp. 964-967.
Typ publikacji :: Journal Article
MeSH Terms :: Betacoronavirus/*isolation & purification
High-Throughput Nucleotide Sequencing/*methods
RNA, Viral/*isolation & purification
Real-Time Polymerase Chain Reaction/*methods
Betacoronavirus/genetics ; High-Throughput Nucleotide Sequencing/instrumentation ; High-Throughput Nucleotide Sequencing/standards ; Humans ; RNA, Viral/genetics ; Real-Time Polymerase Chain Reaction/instrumentation ; Real-Time Polymerase Chain Reaction/standards ; Reproducibility of Results ; SARS-CoV-2 ; Sensitivity and Specificity ; Time Factors
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Expanding Use of Clinical Genome Sequencing and the Need for More Data on Implementation.
Autorzy :: Phillips KA; Center for Translational and Policy Research on Personalized Medicine (TRANSPERS), Department of Clinical Pharmacy, University of California, San Francisco.; Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco.
Douglas MP; Center for Translational and Policy Research on Personalized Medicine (TRANSPERS), Department of Clinical Pharmacy, University of California, San Francisco.
Marshall DA; Cumming School of Medicine, Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.; O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada.; Pokaż więcej
Źródło :: JAMA [JAMA] 2020 Nov 24; Vol. 324 (20), pp. 2029-2030.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Genetic Testing/*trends
High-Throughput Nucleotide Sequencing/*trends
Female ; High-Throughput Nucleotide Sequencing/economics ; High-Throughput Nucleotide Sequencing/statistics & numerical data ; Humans ; Insurance Coverage ; Medicaid ; Medicare ; Pregnancy ; Sequence Analysis, DNA/methods ; United States ; Whole Exome Sequencing
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Long-read metagenomics using PromethION uncovers oral bacteriophages and their interaction with host bacteria.
Autorzy :: Yahara K; Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan. .
Suzuki M; Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Hirabayashi A; Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Suda W; Laboratory for Microbiome Science, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.
Hattori M; Laboratory for Microbiome Science, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.
Suzuki Y; Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Bunkyo City, Japan.
Okazaki Y; Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.; Pokaż więcej
Źródło :: Nature communications [Nat Commun] 2021 Jan 04; Vol. 12 (1), pp. 27. Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Metagenomics*
Bacteria/*virology
Bacteriophages/*genetics
Host-Pathogen Interactions/*genetics
Mouth/*microbiology
Mouth/*virology
Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; DNA Contamination ; DNA, Viral/genetics ; Drug Resistance, Microbial/genetics ; Genes, Viral ; Genome, Bacterial ; Humans ; Integrases/genetics ; Metagenome ; Prophages/genetics ; Proteomics ; Streptococcus/virology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: MINERVA: A Facile Strategy for SARS-CoV-2 Whole-Genome Deep Sequencing of Clinical Samples.
Autorzy :: Chen C; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China.
Li J; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Di L; Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; School of Life Sciences, Peking University, Beijing 100871, China.
Jing Q; Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China.
Du P; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China.
Song C; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China.
Li J; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China.
Li Q; School of Life Sciences, Tsinghua University, Beijing 100084, China.
Cao Y; Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Xie XS; Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Wu AR; Division of Life Science, Hong Kong University of Science and Technology, Hong Kong SAR, China; Department of Chemical and Biological Engineering, Hong Kong University of Science and Technology, Hong Kong SAR, China; Hong Kong Branch of Guangdong Southern Marine Science and Engineering Laboratory (Guangzhou), The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. Electronic address: .
Zeng H; Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University and Beijing Key Laboratory of Emerging Infectious Diseases, Beijing 100015, China. Electronic address: .
Huang Y; Beijing Advanced Innovation Center for Genomics (ICG), Biomedical Pioneering Innovation Center (BIOPIC), Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China; College of Chemistry and Molecular Engineering, Beijing 100871, China; Institute for Cell Analysis, Shenzhen Bay Laboratory, Guangdong 518132, China; Chinese Institute for Brain Research (CIBR), Beijing 102206, China. Electronic address: .
Wang J; School of Life Sciences, Tsinghua University, Beijing 100084, China; Chinese Institute for Brain Research (CIBR), Beijing 102206, China; Beijing Advanced Innovation Center for Structural Biology (ICSB), Tsinghua University, Beijing 100084, China. Electronic address: .; Pokaż więcej
Źródło :: Molecular cell [Mol Cell] 2020 Dec 17; Vol. 80 (6), pp. 1123-1134.e4. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :: Journal Article
MeSH Terms :: Genome, Viral*
High-Throughput Nucleotide Sequencing*
Whole Genome Sequencing*
COVID-19/*genetics
RNA, Viral/*genetics
SARS-CoV-2/*genetics
Animals ; Humans ; Mice ; NIH 3T3 Cells ; RNA, Viral/metabolism ; SARS-CoV-2/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Single-molecule DNA sequencing of widely varying GC-content using nucleotide release, capture and detection in microdroplets.
Autorzy :: Puchtler TJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Johnson K; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Palmer RN; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Talbot EL; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Ibbotson LA; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Powalowska PK; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Knox R; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Shibahara A; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
M S Cunha P; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Newell OJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Wu M; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Chana J; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Athanasopoulou EN; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Waeber AM; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Stolarek M; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Silva AL; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Mordaka JM; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Haggis-Powell M; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Xyrafaki C; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Bush J; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Topkaya IS; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Sosna M; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Ingham RJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Huckvale T; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Negrea A; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Breiner B; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Šlikas J; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Kelly DJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Dunning AJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Bell NM; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Dethlefsen M; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Love DM; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Dear PH; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Kuleshova J; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Podd GJ; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Isaac TH; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Balmforth BW; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.
Frayling CA; Base 4 Innovation Ltd, Broers Building, JJ Thomson Avenue, Cambridge CB3 0FA, UK.; Pokaż więcej
Źródło :: Nucleic acids research [Nucleic Acids Res] 2020 Dec 16; Vol. 48 (22), pp. e132.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Single Molecule Imaging*
DNA/*genetics
Sequence Analysis, DNA/*methods
Base Composition/genetics ; Humans ; Nanotechnology ; Nucleotides/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Exome Sequencing as Part of a Multidisciplinary Approach to Diagnosis-Reply.
Autorzy :: Friedman JM; Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
Jones KL; Department of Pediatrics, University of California, San Diego.
Carey JC; Department of Pediatrics, University of Utah Health, Salt Lake City.; Pokaż więcej
Źródło :: JAMA [JAMA] 2020 Dec 15; Vol. 324 (23), pp. 2445-2446.
Typ publikacji :: Letter; Comment
MeSH Terms :: Exome*
High-Throughput Nucleotide Sequencing*
Whole Exome Sequencing
: Opinia redakcyjna

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: Cancer of unknown primary.
Autorzy :: Lee MS; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sanoff HK; Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Pokaż więcej
Źródło :: BMJ (Clinical research ed.) [BMJ] 2020 Dec 07; Vol. 371, pp. m4050. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Gene Expression Profiling*
High-Throughput Nucleotide Sequencing*
Molecular Diagnostic Techniques*
Biomarkers, Tumor/*metabolism
Neoplasms, Unknown Primary/*diagnosis
Anaplastic Lymphoma Kinase/genetics ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biopsy ; Circulating Tumor DNA/genetics ; Genes, erbB-1 ; Genes, erbB-2 ; Humans ; Lymph Nodes/pathology ; Mammography ; Molecular Targeted Therapy ; Mutation ; Neoplasms, Unknown Primary/drug therapy ; Neoplasms, Unknown Primary/epidemiology ; Neoplasms, Unknown Primary/genetics ; Occult Blood ; Physical Examination ; Physical Functional Performance ; Positron Emission Tomography Computed Tomography ; Proto-Oncogene Proteins B-raf/genetics ; Real-Time Polymerase Chain Reaction ; Risk Assessment ; Tomography, X-Ray Computed
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Tissue-associated microbial detection in cancer using human sequencing data.
Autorzy :: Rodriguez RM; Bioinformatics Core, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Mānoa, Honolulu, HI, USA.; Population Sciences in the Pacific Program-Cancer Epidemiology, Honolulu, HI, USA.; NIDDK Central Repository, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, USA.
Khadka VS; Bioinformatics Core, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Mānoa, Honolulu, HI, USA. .
Menor M; Bioinformatics Core, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Mānoa, Honolulu, HI, USA.
Hernandez BY; Epidemiology, University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI, USA. .; Population Sciences in the Pacific Program-Cancer Epidemiology, Honolulu, HI, USA. .
Deng Y; Bioinformatics Core, Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii, Mānoa, Honolulu, HI, USA. .; Pokaż więcej
Źródło :: BMC bioinformatics [BMC Bioinformatics] 2020 Dec 03; Vol. 21 (Suppl 9), pp. 523. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :: Journal Article; Review
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Microbiota/*genetics
Neoplasms/*microbiology
Organ Specificity/*genetics
Computational Biology ; Humans
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 9 9.

Tytuł :: Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol.
Autorzy :: Redman MW; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Electronic address: .
Papadimitrakopoulou VA; Department of Thoracic Head and Neck Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Minichiello K; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Hirsch FR; Department of Medicine, Division of Hematology and Oncology, Tisch Cancer Institute at Mount Sinai, New York, NY, USA.
Mack PC; Department of Medicine, Division of Hematology and Oncology, Tisch Cancer Institute at Mount Sinai, New York, NY, USA.
Schwartz LH; Department of Radiology, Division of Abdominal Imaging, Columbia University Medical College, New York, NY, USA.
Vokes E; Department of Medicine, University of Chicago, Chicago, IL, USA.
Ramalingam S; Department of Hematology and Oncology, Emory University, Atlanta, GA, USA.
Leighl N; Princess Margaret Hospital, Toronto, ON, Canada.
Bradley J; Department of Radiation Oncology, Emory University, Atlanta, GA, USA.
Miao J; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Moon J; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Highleyman L; SWOG Data Operations Center, Cancer Research and Biostatistics, Seattle, WA, USA.
Miwa C; SWOG Operations Office, San Antonio, TX, USA.
LeBlanc ML; SWOG Statistics and Data Management Center, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Malik S; National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Miller VA; Foundation Medicine, Cambridge, MA, USA.
Sigal EV; Friends of Cancer Research, Washington, DC, USA.
Adam S; Foundation for the National Institutes of Health, Bethesda, MD, USA.
Wholley D; Foundation for the National Institutes of Health, Bethesda, MD, USA.
Sigman C; CCS Associates, San Jose, CA, USA.
Smolich B; CCS Associates, San Jose, CA, USA.
Blanke CD; SWOG Group Chair's Office and Knight Cancer Institute, School of Medicine, Oregon Health and Science University, Portland, OR, USA.
Kelly K; Department of Internal Medicine, UC Davis Comprehensive Cancer Center, Sacramento, CA, USA.
Gandara DR; Department of Internal Medicine, UC Davis Comprehensive Cancer Center, Sacramento, CA, USA.
Herbst RS; Department of Medicine, Yale Cancer Center, New Haven, CT, USA.; Pokaż więcej
Źródło :: The Lancet. Oncology [Lancet Oncol] 2020 Dec; Vol. 21 (12), pp. 1589-1601. Date of Electronic Publication: 2020 Oct 27.
Typ publikacji :: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Molecular Targeted Therapy*
Precision Medicine*
Biomarkers, Tumor/*genetics
Carcinoma, Non-Small-Cell Lung/*drug therapy
Carcinoma, Squamous Cell/*drug therapy
Lung Neoplasms/*drug therapy
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/pathology ; Clinical Decision-Making ; Disease Progression ; Female ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Predictive Value of Tests ; Progression-Free Survival ; Time Factors ; Young Adult
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Targeted next-generation sequencing reveals molecular heterogeneity in non-chronic lymphocytic leukemia clonal B-cell lymphocytosis.
Autorzy :: Defrancesco I; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Zibellini S; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Boveri E; Anatomic Pathology Section, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Frigeni M; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Division of Hematology, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy.
Ferretti VV; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Rizzo E; enGenome srl, Pavia, Italy.
Bonometti A; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Anatomic Pathology Section, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Capuano F; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Anatomic Pathology Section, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Candido C; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Rattotti S; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Tenore A; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Picone C; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Flospergher E; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Zerbi C; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Bergamini F; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Fabbri N; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Cristinelli C; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
Varettoni M; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Paulli M; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Anatomic Pathology Section, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Arcaini L; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.; Pokaż więcej
Źródło :: Hematological oncology [Hematol Oncol] 2020 Dec; Vol. 38 (5), pp. 689-697. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :: Journal Article
MeSH Terms :: Biomarkers, Tumor*
Genetic Heterogeneity*
High-Throughput Nucleotide Sequencing*
Leukemia, Lymphocytic, Chronic, B-Cell/*diagnosis
Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
Aged ; Alleles ; Disease Susceptibility ; Female ; Gene Expression ; Genetic Predisposition to Disease ; Humans ; Immunoglobulin Heavy Chains/genetics ; Immunohistochemistry ; Immunophenotyping ; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism ; Male ; Middle Aged ; Mutation
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: Targeted next-generation sequencing as a diagnostic tool in gastrointestinal system cancer/polyposis patients.
Autorzy :: Yalcintepe S; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Gurkan H; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Demir S; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Tozkir H; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Tezel HA; Department of Gastroenterology, Trakya University Faculty of Medicine, Edirne, Turkey.
Atli EI; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Atli E; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Eker D; Department of Medical Genetics, Trakya University Faculty of Medicine, Edirne, Turkey.
Cicin I; Department of Medical Oncology, Trakya University Faculty of Medicine, Edirne, Turkey.; Pokaż więcej
Źródło :: Tumori [Tumori] 2020 Dec; Vol. 106 (6), pp. 510-517. Date of Electronic Publication: 2020 May 11.
Typ publikacji :: Journal Article
MeSH Terms :: Biomarkers, Tumor*
Genetic Testing*/methods
High-Throughput Nucleotide Sequencing*/methods
Adenomatous Polyposis Coli/*diagnosis
Adenomatous Polyposis Coli/*genetics
Gastrointestinal Neoplasms/*diagnosis
Gastrointestinal Neoplasms/*genetics
Adult ; Aged ; Alleles ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Retrospective Studies ; Young Adult
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: [Gene mutation analysis of 19 Uighur families with aortic disease in Kashgar, China].
Autorzy :: Yu C; Guangdong Provincial People's Hospital//Guangdong Cardiovascular Institute//Guangdong Provincial Key Laboratory of South China Structural Heart Disease//Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Li Y; Guangdong Provincial People's Hospital//Guangdong Cardiovascular Institute//Guangdong Provincial Key Laboratory of South China Structural Heart Disease//Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Department of Cardiac Surgery, Guangdong Provincial People's Hospital Affiliated to South China University of Technology, Guangzhou 510100, China.
Adilijang A; Department of Cardiac Surgery, First People Hospital of Kashgar, Kashgar 844000, China.
Yan J; Department of Cardiac Surgery, First People Hospital of Kashgar, Kashgar 844000, China.
Guzalnur A; Department of Cardiac Surgery, First People Hospital of Kashgar, Kashgar 844000, China.
Abudushalamu A; Department of Cardiac Surgery, First People Hospital of Kashgar, Kashgar 844000, China.
Aimirela Y; Department of Cardiac Surgery, First People Hospital of Kashgar, Kashgar 844000, China.
Fan R; Guangdong Provincial People's Hospital//Guangdong Cardiovascular Institute//Guangdong Provincial Key Laboratory of South China Structural Heart Disease//Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Pokaż więcej
Źródło :: Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2020 Nov 30; Vol. 40 (11), pp. 1607-1614.
Typ publikacji :: Journal Article
MeSH Terms :: Aortic Diseases*
High-Throughput Nucleotide Sequencing*
China ; Genetic Predisposition to Disease/genetics ; Humans ; Mutation ; Phenotype
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Novel target capture DNA library preparation method using CircLigase-mediated hook ligation.
Autorzy :: Ren H; BGI (Beijing Genomics Institute) Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China; BGI (Beijing Genomics Institute)-Shenzhen, Shenzhen 518083, China; Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Xi Y; MGI (Manufacturing Genomics Institute), BGI-Shenzhen, Shenzhen 518083, China.
Li Z; MGI (Manufacturing Genomics Institute), BGI-Shenzhen, Shenzhen 518083, China.
Zhang D; BGI (Beijing Genomics Institute)-Shenzhen, Shenzhen 518083, China; Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Huang F; BGI (Beijing Genomics Institute) Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China; School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, China.
Fang X; Laboratory for Innovative Molecular Diagnostics, Guangdong Provincial Academician Workstation of BGI Synthetic Genomics, BGI-Shenzhen, Beishan Industrial Zone, Shenzhen, 518083, China.
Zhao X; MGI (Manufacturing Genomics Institute), BGI-Shenzhen, Shenzhen 518083, China.
Zhang X; BGI (Beijing Genomics Institute) Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China; BGI (Beijing Genomics Institute)-Shenzhen, Shenzhen 518083, China.
Chen A; BGI (Beijing Genomics Institute)-Shenzhen, Shenzhen 518083, China.
Chen T; Laboratory for Innovative Molecular Diagnostics, Guangdong Provincial Academician Workstation of BGI Synthetic Genomics, BGI-Shenzhen, Beishan Industrial Zone, Shenzhen, 518083, China.
Jiang Y; BGI (Beijing Genomics Institute) Education Center, University of Chinese Academy of Sciences, Shenzhen, 518083, China; BGI (Beijing Genomics Institute)-Shenzhen, Shenzhen 518083, China; Complete Genomics Inc., 2904 Orchard Pkwy, San Jose, CA 95134 USA; Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen, China. Electronic address: .; Pokaż więcej
Źródło :: New biotechnology [N Biotechnol] 2020 Nov 25; Vol. 59, pp. 44-50. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :: Journal Article
MeSH Terms :: Computational Biology*
High-Throughput Nucleotide Sequencing*
Sequence Analysis, DNA*
DNA/*genetics
DNA Ligases/*metabolism
Biotechnology ; DNA/metabolism ; Gene Library
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients.
Autorzy :: Mostafa HH; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Fissel JA; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Fanelli B; CosmosID, Inc., Rockville, Maryland, USA.
Bergman Y; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gniazdowski V; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dadlani M; CosmosID, Inc., Rockville, Maryland, USA.
Carroll KC; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Colwell RR; CosmosID, Inc., Rockville, Maryland, USA.; University of Maryland College Park, Institute for Advanced Computer Studies, College Park, Maryland, USA.
Simner PJ; Division of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA .; Pokaż więcej
Źródło :: MBio [mBio] 2020 Nov 20; Vol. 11 (6). Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :: Journal Article
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Metagenomics*
COVID-19/*virology
Nasopharynx/*virology
SARS-CoV-2/*genetics
Bacteria/classification ; COVID-19/microbiology ; Coinfection/microbiology ; Coinfection/virology ; Computational Biology ; Humans ; Metagenome ; Microbiota ; RNA, Viral/genetics ; Specimen Handling
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Highly accurate long-read HiFi sequencing data for five complex genomes.
Autorzy :: Hon T; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Mars K; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Young G; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Tsai YC; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Karalius JW; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Landolin JM; Ravel Biotechnology Inc., 953 Indiana St., San Francisco, CA, 94107, USA.
Maurer N; Department of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA.
Kudrna D; Arizona Genomics Institute and School of Plant Sciences, University of Arizona, Tucson, AZ, 85721, USA.
Hardigan MA; Department of Plant Sciences, University of California, Davis, One Shields Ave, Davis, CA, 95616-8571, USA.
Steiner CC; Conservation Genetics, Beckman Center for Conservation Research, San Diego Zoo Global, 15600 San Pasqual Valley Road, Escondido, CA, 92027, USA.
Knapp SJ; Department of Plant Sciences, University of California, Davis, One Shields Ave, Davis, CA, 95616-8571, USA.
Ware D; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.; USDA-ARS, Plant, Soil, and Nutrition Research Unit, Ithaca, NY, 14853, USA.
Shapiro B; Department of Ecology and Evolutionary Biology, University of California Santa Cruz, Santa Cruz, CA, 95064, USA.; Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA, 95064, USA.
Peluso P; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA.
Rank DR; Pacific Biosciences of California Inc., 1305 O'Brien Dr., Menlo Park, CA, 94025, USA. .; Pokaż więcej
Źródło :: Scientific data [Sci Data] 2020 Nov 17; Vol. 7 (1), pp. 399. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :: Dataset; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Mice/*genetics
Zea mays/*genetics
Animals ; Fragaria/genetics ; Genome, Plant ; Metagenome ; Ranidae/genetics ; Sequence Analysis, DNA
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Clover: a clustering-oriented de novo assembler for Illumina sequences.
Autorzy :: Hsieh MF; Department of Computer Science, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Lu CL; Department of Computer Science, National Tsing Hua University, Hsinchu, 30013, Taiwan.
Tang CY; Department of Computer Science, National Tsing Hua University, Hsinchu, 30013, Taiwan. .; Department of Computer Science and Information Engineering, Providence University, Taichung, 43301, Taiwan. .; Pokaż więcej
Źródło :: BMC bioinformatics [BMC Bioinformatics] 2020 Nov 17; Vol. 21 (1), pp. 528. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :: Journal Article
MeSH Terms :: Algorithms*
High-Throughput Nucleotide Sequencing*
Base Sequence ; Chromosomes, Human, Pair 14/genetics ; Cluster Analysis ; Genome, Bacterial ; Genomics/methods ; Humans ; Software ; Time Factors
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 17 17.

Tytuł :: Natrix: a Snakemake-based workflow for processing, clustering, and taxonomically assigning amplicon sequencing reads.
Autorzy :: Welzel M; Department of Mathematics and Computer Science, University of Marburg, Marburg, Germany.
Lange A; Department of Bioinformatics and Computational Biophysics, University of Duisburg-Essen, Essen, Germany.
Heider D; Department of Mathematics and Computer Science, University of Marburg, Marburg, Germany.
Schwarz M; Department of Mathematics and Computer Science, University of Marburg, Marburg, Germany.
Freisleben B; Department of Mathematics and Computer Science, University of Marburg, Marburg, Germany.
Jensen M; Department of Biodiversity, University of Duisburg-Essen, Essen, Germany.
Boenigk J; Department of Biodiversity, University of Duisburg-Essen, Essen, Germany.
Beisser D; Department of Biodiversity, University of Duisburg-Essen, Essen, Germany. .; Pokaż więcej
Źródło :: BMC bioinformatics [BMC Bioinformatics] 2020 Nov 16; Vol. 21 (1), pp. 526. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :: Journal Article
MeSH Terms :: High-Throughput Nucleotide Sequencing*
Software*
Workflow*
Cluster Analysis ; Data Analysis ; Databases, Genetic ; Environmental DNA/genetics ; Environmental DNA/isolation & purification ; Floods ; Microbiota/genetics ; Reproducibility of Results
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 18 18.

Tytuł :: Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer.
Autorzy :: Yildiz Tacar S; Department of Medical Oncology, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey; Department of Medical Oncology, Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Bozgeyik E; Department of Medical Biology, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey; Department of Medical Services and Techniques, Vocational School of Health Services, Adiyaman University, Adiyaman, Turkey. Electronic address: .
Seber ES; Department of Medical Oncology, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Yetisyigit T; Department of Medical Oncology, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Tozkir H; Department of Medical Genetics, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Avci O; Department of Medical Oncology, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.
Arslan A; Department of Medical Genetics, Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey.; Pokaż więcej
Źródło :: Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118334. Date of Electronic Publication: 2020 Aug 23.
Typ publikacji :: Journal Article
MeSH Terms :: High-Throughput Nucleotide Sequencing*
BRCA1 Protein/*genetics
BRCA2 Protein/*genetics
Breast Neoplasms/*genetics
Adolescent ; Adult ; Aged ; Breast Neoplasms/pathology ; Female ; Genetic Predisposition to Disease ; Humans ; Middle Aged ; Mutation ; Young Adult
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: [Increasing the Uniformity of Genome Fragment Coverage for High-Throughput Sequencing of Influenza A Virus].
Autorzy :: Mikhaylova YV; Central Research Institute of Epidemiology, of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, 111123 Russia.; .
Shelenkov AA; Central Research Institute of Epidemiology, of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, 111123 Russia.
Yanushevich YG; Central Research Institute of Epidemiology, of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, 111123 Russia.
Shagin DA; Central Research Institute of Epidemiology, of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, 111123 Russia.; Pirogov Russian National Research Medical University, Moscow, 117997 Russia.; Pokaż więcej
Źródło :: Molekuliarnaia biologiia [Mol Biol (Mosk)] 2020 Nov-Dec; Vol. 54 (6), pp. 968-974.
Typ publikacji :: Journal Article
MeSH Terms :: Genome, Viral*
High-Throughput Nucleotide Sequencing*
Influenza A virus*/genetics
Polymerase Chain Reaction
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity.
Autorzy :: Lazzarotto CR; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Malinin NL; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Li Y; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Zhang R; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Yang Y; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Lee G; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Cowley E; Roche Sequencing & Life Science, Roche Diagnostics, Indianapolis, IN, USA.
He Y; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.; Department of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, Honolulu, HI, USA.
Lan X; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Jividen K; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Katta V; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Kolmakova NG; National Institute of Standards and Technology, Gaithersburg, MD, USA.
Petersen CT; Department of Bone Marrow Transplantation & Cellular Therapy, St Jude Children's Research Hospital, Memphis, TN, USA.
Qi Q; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Strelcov E; Physical Measurement Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA.; Maryland NanoCenter, University of Maryland, College Park, MD, USA.
Maragh S; National Institute of Standards and Technology, Gaithersburg, MD, USA.
Krenciute G; Department of Bone Marrow Transplantation & Cellular Therapy, St Jude Children's Research Hospital, Memphis, TN, USA.
Ma J; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Cheng Y; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.
Tsai SQ; Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA. .; Pokaż więcej
Źródło :: Nature biotechnology [Nat Biotechnol] 2020 Nov; Vol. 38 (11), pp. 1317-1327. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Epigenesis, Genetic*
High-Throughput Nucleotide Sequencing*
CRISPR-Associated Protein 9/*metabolism
CRISPR-Cas Systems/*genetics
Base Sequence ; Cell Line ; Chromatin/genetics ; Gene Editing ; Genetic Variation ; Genome, Human ; Humans ; Machine Learning
: Czasopismo naukowe

Szczegóły

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