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Wyszukujesz frazę ""High-Throughput Screening Assays"" wg kryterium: Temat


Tytuł:
Compact Micropatterned Chip Empowers Undisturbed and Programmable Drug Addition in High-Throughput Cell Screening.
Autorzy:
Zhao Y; College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.
Sun Y; College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.
Xie X; College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.
Liang Y; College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.
Cavalcanti-Adam EA; Cellular Biomechanics, Faculty of Engineering Sciences, University of Bayreuth, 95447, Bayreuth, Germany.
Feng W; College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China.; State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu, 610065, China.
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Źródło:
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Mar; Vol. 36 (11), pp. e2306814. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Cyclodextrins*
Polymers/chemistry ; Azo Compounds/chemistry
Czasopismo naukowe
Tytuł:
High-Throughput Screening of Surface Engineered Cyanine Nanodots for Active Transport of Therapeutic Antibodies into Solid Tumor.
Autorzy:
Qin Y; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.; ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311200, China.
Wang G; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.; ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou, 311200, China.
Chen L; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
Sun Y; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
Yang J; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
Piao Y; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
Shen Y; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
Zhou Z; Zhejiang Key Laboratory of Smart Biomaterials and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China.
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Źródło:
Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Mar; Vol. 36 (9), pp. e2302292. Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Neoplasms*/drug therapy
Animals ; Mice ; Transcytosis ; Adsorption ; Amino Acids ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Establishing an ANO1-Based Cell Model for High-Throughput Screening Targeting TRPV4 Regulators.
Autorzy:
Zheng K; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hu J; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hu C; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Liu X; School of Medical Technology, Beihua University, Jilin 132000, China.
Wang Y; School of Medical Technology, Beihua University, Jilin 132000, China.
Han H; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Xing W; School of Medical Technology, Beihua University, Jilin 132000, China.
Yang L; School of Medical Technology, Beihua University, Jilin 132000, China.
Zhang J; Zhiyuan College, Shanghai Jiao Tong University, Shanghai 200240, China.
Hong Q; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hao F; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Li W; Jilin Collaborative Innovation Center for Antibody Engineering, Jilin Medical University, Jilin 132000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 28; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
TRPV Cation Channels*/metabolism
High-Throughput Screening Assays*
Anoctamin-1 ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
High-Throughput Screening Techniques for the Selection of Thermostable Enzymes.
Autorzy:
Li L; State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Liu X; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Bai Y; State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Yao B; State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Luo H; State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Tu T; State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
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Źródło:
Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Feb 28; Vol. 72 (8), pp. 3833-3845. Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
High-Throughput Screening Assays*/methods
Protein Engineering*/methods
Enzymes ; Enzyme Stability
Czasopismo naukowe
Tytuł:
Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells.
Autorzy:
Rajendra E; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Grande D; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Mason B; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Di Marcantonio D; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Armstrong L; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Hewitt G; The Francis Crick Institute, London NW1 1AT, UK.
Elinati E; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Galbiati A; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Boulton SJ; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.; The Francis Crick Institute, London NW1 1AT, UK.
Heald RA; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Smith GCM; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
Robinson HMR; Artios Pharma Ltd, Babraham Research Campus, Cambridge CB22 3FH, UK.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2024 Feb 28; Vol. 52 (4), pp. 1736-1752.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*/genetics
High-Throughput Screening Assays*
DNA/metabolism ; DNA Breaks, Double-Stranded ; DNA End-Joining Repair ; Homologous Recombination ; Recombinational DNA Repair ; Humans ; Cell Line
Czasopismo naukowe
Tytuł:
"High-throughput screening of catalytically active inclusion bodies using laboratory automation and Bayesian optimization".
Autorzy:
Helleckes LM; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Küsters K; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Wagner C; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Hamel R; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Saborowski R; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
Marienhagen J; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Wiechert W; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Computational Systems Biotechnology (AVT.CSB), RWTH Aachen University, 52074, Aachen, Germany.
Oldiges M; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany. .; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2024 Feb 24; Vol. 23 (1), pp. 67. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Automation, Laboratory*
High-Throughput Screening Assays*
Reproducibility of Results ; Bayes Theorem ; Inclusion Bodies ; Automation
Czasopismo naukowe
Tytuł:
Leveraging CRISPR/Cas12 signal amplifier to sensitive detection of apurinic/apyrimidinic endonuclease 1 and high-throughput inhibitor screening.
Autorzy:
Ding S; Clinical Medical College & Affiliated Hospital, Chengdu University, Chengdu, 610041, PR China.
Yuan Y; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, 610041, PR China.
Dong J; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, 610041, PR China.
Du F; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, 610041, PR China. Electronic address: .
Cui X; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, 610041, PR China.
Shi Z; Clinical Medical College & Affiliated Hospital, Chengdu University, Chengdu, 610041, PR China.
Tang Z; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Science, Chengdu, 610041, PR China. Electronic address: .
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Źródło:
Analytica chimica acta [Anal Chim Acta] 2024 Feb 22; Vol. 1291, pp. 342212. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
CRISPR-Cas Systems*
DNA Repair ; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism ; Endonucleases/metabolism
Czasopismo naukowe
Tytuł:
MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery.
Autorzy:
Brocklehurst CE; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Altmann E; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Bon C; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Davis H; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Dunstan D; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Ertl P; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Ginsburg-Moraff C; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Grob J; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Gosling DJ; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Lapointe G; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Marziale AN; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Mues H; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Palmieri M; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Racine S; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
Robinson RI; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Springer C; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Tan K; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Ulmer W; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States.
Wyler R; Global Discovery Chemistry, Novartis Biomedical Research, Novartis Pharma AG, Basel 4033, Switzerland.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2024 Feb 08; Vol. 67 (3), pp. 2118-2128. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Drug Discovery*
High-Throughput Screening Assays*
Czasopismo naukowe
Tytuł:
Potent inhibitors targeting cyclin-dependent kinase 9 discovered via virtual high-throughput screening and absolute binding free energy calculations.
Autorzy:
Wang S; School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China. .
Liu F; School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China. .
Li P; Single Particle, LLC, 10531 4S Commons Dr 166-629, San Diego, CA 92127, USA.
Wang JN; State Key Laboratory of Precision Spectroscopy, School of Physics and Electronic Science, East China Normal University, Shanghai 200241, China.
Mo Y; State Key Laboratory of Precision Spectroscopy, School of Physics and Electronic Science, East China Normal University, Shanghai 200241, China.; NYU-ECNU Center for Computational Chemistry at NYU Shanghai, Shanghai 200062, China.; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 030006, China.
Lin B; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China. .
Mei Y; State Key Laboratory of Precision Spectroscopy, School of Physics and Electronic Science, East China Normal University, Shanghai 200241, China.; NYU-ECNU Center for Computational Chemistry at NYU Shanghai, Shanghai 200062, China.; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 030006, China.
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Źródło:
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2024 Feb 07; Vol. 26 (6), pp. 5377-5386. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Cyclin-Dependent Kinase 9*
Protein Binding ; Entropy ; Molecular Docking Simulation ; Molecular Dynamics Simulation
Czasopismo naukowe
Tytuł:
Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 .
Autorzy:
Bothe U; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Günther J; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Nubbemeyer R; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Siebeneicher H; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Ring S; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Bömer U; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Peters M; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Rausch A; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Denner K; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Himmel H; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Sutter A; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Terebesi I; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Lange M; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Wengner AM; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Guimond N; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Thaler T; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Platzek J; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Eberspächer U; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Schäfer M; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Steuber H; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Zollner TM; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Steinmeyer A; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
Schmidt N; Bayer AG, Research & Development, Pharmaceuticals, 13353 Berlin, Germany.
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Źródło:
Journal of medicinal chemistry [J Med Chem] 2024 Jan 25; Vol. 67 (2), pp. 1225-1242. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-1 Receptor-Associated Kinases*
High-Throughput Screening Assays*
Indazoles*
Pyridines*
Animals ; Humans ; Binding Sites ; Inflammation
Czasopismo naukowe
Tytuł:
PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan.
Autorzy:
Alfatah M; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore. .
Zhang Y; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.
Naaz A; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome #02-01, Singapore, 138672, Republic of Singapore.
Cheng TYN; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.
Eisenhaber F; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.; LASA - Lausitz Advanced Scientific Applications gGmbH, Straße der Einheit 2-24, 02943, Weißwasser, Federal Republic of Germany.; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, 637551, Republic of Singapore.
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Źródło:
Biology direct [Biol Direct] 2024 Jan 23; Vol. 19 (1), pp. 8. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Longevity*
High-Throughput Screening Assays*
Humans ; Cell Line ; Mannitol ; Reproduction
Czasopismo naukowe
Tytuł:
Microfluidics in High-Throughput Drug Screening: Organ-on-a-Chip and C. elegans -Based Innovations.
Autorzy:
Yoon S; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.
Kilicarslan You D; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.
Jeong U; Department of Mechanical Engineering, Inha University, Incheon 22212, Republic of Korea.
Lee M; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.
Kim E; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.
Jeon TJ; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.; Department of Biological Engineering, Inha University, Incheon 22212, Republic of Korea.; Biohybrid Systems Research Center (BSRC), Inha University, Incheon 22212, Republic of Korea.
Kim SM; Department of Biological Sciences and Bioengineering, Inha University, Incheon 22212, Republic of Korea.; Department of Mechanical Engineering, Inha University, Incheon 22212, Republic of Korea.; Biohybrid Systems Research Center (BSRC), Inha University, Incheon 22212, Republic of Korea.
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Źródło:
Biosensors [Biosensors (Basel)] 2024 Jan 21; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Microfluidics*
High-Throughput Screening Assays*
Animals ; Humans ; Caenorhabditis elegans ; Drug Evaluation, Preclinical ; Microphysiological Systems ; Lab-On-A-Chip Devices
Czasopismo naukowe
Tytuł:
A Functional Hydrogel Bead-Based High-Throughput Screening System for Mammalian Cells with Enhanced Secretion of Therapeutic Antibodies.
Autorzy:
Wulandari DA; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Tsuru K; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Minamihata K; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Wakabayashi R; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Goto M; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.; Division of Biotechnology, Centre for Future Chemistry, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka 819-0395, Japan.
Kamiya N; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.; Division of Biotechnology, Centre for Future Chemistry, Kyushu University, 744 Motooka, Nishi-Ku, Fukuoka 819-0395, Japan.
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Źródło:
ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2024 Jan 08; Vol. 10 (1), pp. 628-636. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Hydrogels*/metabolism
Animals ; Hybridomas/metabolism ; Recombinant Proteins/metabolism ; Disulfides/metabolism ; Mammals
Czasopismo naukowe
Tytuł:
Decoding endocrine cell differentiation: insights from high-throughput CRISPR screening in human gut organoids.
Autorzy:
Lin L; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1526.
Typ publikacji:
Journal Article
MeSH Terms:
Clustered Regularly Interspaced Short Palindromic Repeats*
High-Throughput Screening Assays*
Humans ; Cell Differentiation/genetics ; Organoids
Czasopismo naukowe
Tytuł:
Establishment and application of high throughput screening cell model for nutrient regulation of embryonic development.
Autorzy:
Wang X; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Huang J; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Li H; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Li Y; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Cai S; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Xue B; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Zhu Z; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Zeng X; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China.
Zeng X; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China; Beijing Key Laboratory of Biofeed Additives, China Agricultural University, Beijing, China. Electronic address: .
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Źródło:
The Journal of nutritional biochemistry [J Nutr Biochem] 2024 Jan; Vol. 123, pp. 109502. Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Embryonic Development*/genetics
Female ; Swine ; Pregnancy ; Rats ; Humans ; Animals ; Resveratrol/pharmacology ; Antioxidants/pharmacology ; Nutrients ; Mammals
Czasopismo naukowe
Tytuł:
Virtual plates: Getting the best out of high content screens.
Autorzy:
Shapira Lots I; Anima Biotech Ltd., 2 Shoham St., Ramat Gan 5251003, Israel. Electronic address: .
Alroy I; Anima Biotech Ltd., 2 Shoham St., Ramat Gan 5251003, Israel.
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Źródło:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2024 Jan; Vol. 29 (1), pp. 77-85. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Artificial Intelligence*
High-Throughput Screening Assays*/methods
Humans ; Image Processing, Computer-Assisted/methods ; Machine Learning
Czasopismo naukowe
Tytuł:
Advances in ligand-specific biosensing for structurally similar molecules.
Autorzy:
Xi C; Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Diao J; Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Moon TS; Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, MO, USA; Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: .
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Źródło:
Cell systems [Cell Syst] 2023 Dec 20; Vol. 14 (12), pp. 1024-1043.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
High-Throughput Screening Assays*
Biosensing Techniques*/methods
Ligands
Czasopismo naukowe
Tytuł:
DMSO-tolerant ornithine decarboxylase (ODC) tandem assay optimised for high-throughput screening.
Autorzy:
Park MG; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
Kim SY; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
Lee CJ; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 309-318.
Typ publikacji:
Journal Article
MeSH Terms:
Ornithine Decarboxylase*
High-Throughput Screening Assays*
Humans ; Dimethyl Sulfoxide ; Biological Assay ; Putrescine
Czasopismo naukowe
Tytuł:
High-throughput differential scanning fluorimetry (DSF) and cellular thermal shift assays (CETSA): Shifting from manual to automated screening.
Autorzy:
Hansel CS; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK. Electronic address: .
Lanne A; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK.
Rowlands H; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK.
Shaw J; Assay Development, Discovery Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
Collier MJ; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK.
Plant H; High-throughput Screening, Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK.
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Źródło:
SLAS technology [SLAS Technol] 2023 Dec; Vol. 28 (6), pp. 411-415. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*/methods
Drug Discovery*/methods
Proteins/metabolism ; Temperature ; Fluorometry/methods
Czasopismo naukowe
Tytuł:
Streamlining pipeline efficiency: a novel model-agnostic technique for accelerating conditional generative and virtual screening pipelines.
Autorzy:
Viswanathan K; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.
Goel M; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.
Laghuvarapu S; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.
Varma G; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India.
Priyakumar UD; Center for Computational Natural Sciences and Bioinformatics, International Institute of Information Technology, Hyderabad, 500032, India. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 29; Vol. 13 (1), pp. 21069. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
Software*
High-Throughput Screening Assays*
Czasopismo naukowe

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