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Wyszukujesz frazę ""High-Throughput Screening Assays"" wg kryterium: Temat


Tytuł:
Establishing an ANO1-Based Cell Model for High-Throughput Screening Targeting TRPV4 Regulators.
Autorzy:
Zheng K; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hu J; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hu C; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Liu X; School of Medical Technology, Beihua University, Jilin 132000, China.
Wang Y; School of Medical Technology, Beihua University, Jilin 132000, China.
Han H; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Xing W; School of Medical Technology, Beihua University, Jilin 132000, China.
Yang L; School of Medical Technology, Beihua University, Jilin 132000, China.
Zhang J; Zhiyuan College, Shanghai Jiao Tong University, Shanghai 200240, China.
Hong Q; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Hao F; College of Laboratory Medicine, Jilin Medical University, Jilin 132000, China.
Li W; Jilin Collaborative Innovation Center for Antibody Engineering, Jilin Medical University, Jilin 132000, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Feb 28; Vol. 29 (5). Date of Electronic Publication: 2024 Feb 28.
Typ publikacji:
Journal Article
MeSH Terms:
TRPV Cation Channels*/metabolism
High-Throughput Screening Assays*
Anoctamin-1 ; Calcium/metabolism
Czasopismo naukowe
Tytuł:
"High-throughput screening of catalytically active inclusion bodies using laboratory automation and Bayesian optimization".
Autorzy:
Helleckes LM; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Küsters K; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Wagner C; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Hamel R; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Saborowski R; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
Marienhagen J; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany.
Wiechert W; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.; Computational Systems Biotechnology (AVT.CSB), RWTH Aachen University, 52074, Aachen, Germany.
Oldiges M; Institute of Bio- and Geosciences IBG-1: Biotechnology, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany. .; Institute of Biotechnology, RWTH Aachen University, 52074, Aachen, Germany. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2024 Feb 24; Vol. 23 (1), pp. 67. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Automation, Laboratory*
High-Throughput Screening Assays*
Reproducibility of Results ; Bayes Theorem ; Inclusion Bodies ; Automation
Czasopismo naukowe
Tytuł:
PICLS with human cells is the first high throughput screening method for identifying novel compounds that extend lifespan.
Autorzy:
Alfatah M; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore. .
Zhang Y; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.
Naaz A; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome #02-01, Singapore, 138672, Republic of Singapore.
Cheng TYN; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.
Eisenhaber F; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix #07-01, Singapore, 138671, Republic of Singapore.; LASA - Lausitz Advanced Scientific Applications gGmbH, Straße der Einheit 2-24, 02943, Weißwasser, Federal Republic of Germany.; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, 637551, Republic of Singapore.
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Źródło:
Biology direct [Biol Direct] 2024 Jan 23; Vol. 19 (1), pp. 8. Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Longevity*
High-Throughput Screening Assays*
Humans ; Cell Line ; Mannitol ; Reproduction
Czasopismo naukowe
Tytuł:
Decoding endocrine cell differentiation: insights from high-throughput CRISPR screening in human gut organoids.
Autorzy:
Lin L; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, Utrecht, The Netherlands.; Oncode Institute, Utrecht, The Netherlands.; Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1526.
Typ publikacji:
Journal Article
MeSH Terms:
Clustered Regularly Interspaced Short Palindromic Repeats*
High-Throughput Screening Assays*
Humans ; Cell Differentiation/genetics ; Organoids
Czasopismo naukowe
Tytuł:
DMSO-tolerant ornithine decarboxylase (ODC) tandem assay optimised for high-throughput screening.
Autorzy:
Park MG; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
Kim SY; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
Lee CJ; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, South Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, South Korea.
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Źródło:
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 309-318.
Typ publikacji:
Journal Article
MeSH Terms:
Ornithine Decarboxylase*
High-Throughput Screening Assays*
Humans ; Dimethyl Sulfoxide ; Biological Assay ; Putrescine
Czasopismo naukowe
Tytuł:
Smartphone-Based High-Throughput Fluorimetric Assay for Histidine Quantification in Human Urine Using 96-Well Plates.
Autorzy:
Baltzis D; Laboratory of Analytical Chemistry, School of Chemistry, Faculty of Sciences, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
Tsogas GZ; Laboratory of Analytical Chemistry, School of Chemistry, Faculty of Sciences, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
Zacharis CK; Laboratory of Pharmaceutical Analysis, School of Pharmacy, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
Tzanavaras PD; Laboratory of Analytical Chemistry, School of Chemistry, Faculty of Sciences, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 23; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Smartphone*
High-Throughput Screening Assays*
Histidine*/urine
Fluorometry/methods ; Humans ; o-Phthalaldehyde/chemistry
Czasopismo naukowe
Tytuł:
A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay Development.
Autorzy:
Bazzone A; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Barthmes M; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
George C; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Brinkwirth N; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Zerlotti R; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.; RIGeL-Regensburg International Graduate School of Life Sciences, University of Regensburg, 93053 Regensburg, Germany.
Prinz V; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Cole K; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Friis S; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Dickson A; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Rice S; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Lim J; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Fern Toh M; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Mohammadi M; Assay Works, Am BioPark 11, 93053 Regensburg, Germany.
Pau D; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Stone DJ; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Renger JJ; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Fertig N; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 14; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Cardiac Electrophysiology*
Membrane Potentials ; Cations ; Lysosomes
Czasopismo naukowe
Tytuł:
High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells.
Autorzy:
Schmitt DL; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.
Dranchak P; National Institutes of Health, National Center for Advancing Translational Sciences, Rockville, Maryland, United States of America.
Parajuli P; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.
Blivis D; National Institutes of Health, National Center for Advancing Translational Sciences, Rockville, Maryland, United States of America.
Voss T; National Institutes of Health, National Center for Advancing Translational Sciences, Rockville, Maryland, United States of America.
Kohnhorst CL; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.
Kyoung M; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland, United States of America.
Inglese J; National Institutes of Health, National Center for Advancing Translational Sciences, Rockville, Maryland, United States of America.; National Institutes of Health, National Human Genome Research Institute, Bethesda, Maryland, United States of America.
An S; Department of Chemistry and Biochemistry, University of Maryland Baltimore County (UMBC), Baltimore, Maryland, United States of America.; Program in Oncology, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Aug 04; Vol. 18 (8), pp. e0289707. Date of Electronic Publication: 2023 Aug 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural
MeSH Terms:
Aurora Kinase A*
High-Throughput Screening Assays*
Humans ; HeLa Cells ; Cell Cycle ; Glucose/metabolism
Czasopismo naukowe
Tytuł:
In-vitro high-throughput library screening-Kinetics and molecular docking studies of potent inhibitors of α-glucosidase.
Autorzy:
Ali M; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.; Department of Chemistry, Higher Education Department, Government Postgraduate College No.1, Abbottabad, KP, Pakistan.
Malik K; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.
Zaidi A; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.
Farooq U; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.
Bukhari SM; Department of Chemistry, COMSATS University Islamabad, KPK, Abbottabad, Pakistan.
Majeed Z; Faculty of Science, Department of Biotechnology, The University of Azad Jammu and Kashmir, Chehla Campus, Muzaffarabad, Pakistan.
Mahnashi MH; Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Nawazish S; Department of Environmental Sciences, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, Pakistan.
Abdulwahab A; Pediatric Department, Medical College, Najran University, Najran, Saudi Arabia.
Alshaibari KS; Pediatric Department, Medical College, Najran University, Najran, Saudi Arabia.
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Źródło:
PloS one [PLoS One] 2023 Jun 30; Vol. 18 (6), pp. e0286159. Date of Electronic Publication: 2023 Jun 30 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
alpha-Glucosidases*
High-Throughput Screening Assays*
Kinetics ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Predicting cellular responses to complex perturbations in high-throughput screens.
Autorzy:
Lotfollahi M; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.
Klimovskaia Susmelj A; Meta AI, Paris, France.; Swiss Data Science Center, Zurich, Switzerland.
De Donno C; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.; School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Hetzel L; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.; Department of Mathematics, Technical University of Munich, Munich, Germany.
Ji Y; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.; School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
Ibarra IL; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.
Srivatsan SR; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Naghipourfar M; Department of Bioengineering, University of California, Berkeley, CA, USA.
Daza RM; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Martin B; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Shendure J; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
McFaline-Figueroa JL; Department of Biomedical Engineering, Columbia University, New York, NY, USA.
Boyeau P; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
Wolf FA; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.
Yakubova N; Meta AI, Paris, France.
Günnemann S; Department of Computer Science, Technical University of Munich, Munich, Germany.
Trapnell C; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA.
Lopez-Paz D; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.
Theis FJ; Helmholtz Center Munich - German Research Center for Environmental Health, Institute of Computational Biology, Munich, Germany.; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.; School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.; Department of Mathematics, Technical University of Munich, Munich, Germany.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2023 Jun 12; Vol. 19 (6), pp. e11517. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Profiling*
High-Throughput Screening Assays*
Computational Biology*
Single-Cell Gene Expression Analysis*
Czasopismo naukowe
Tytuł:
Expression of Cell-Adhesion Molecules in E. coli : A High Throughput Screening to Identify Paracellular Modulators.
Autorzy:
Rollins J; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Worthington T; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Dransfield A; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Whitney J; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Stanford J; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Hooke E; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Hobson J; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Wengler J; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Hope S; Department of Microbiology and Molecular Biology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
Mizrachi D; Department of Cell Biology and Physiology, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 06; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli*/metabolism
High-Throughput Screening Assays*
Animals ; Cell Adhesion Molecules/genetics ; Cell Adhesion Molecules/metabolism ; Claudins/metabolism ; Cell Line ; Tight Junctions/metabolism ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
Group I Intron as a Potential Target for Antifungal Compounds: Development of a Trans -Splicing High-Throughput Screening Strategy.
Autorzy:
Malbert B; Early Discovery, Biochemistry Excellence, Centre de Recherche La Dargoire, Bayer SAS, 69009 Lyon, France.
Labaurie V; Early Discovery, Biochemistry Excellence, Centre de Recherche La Dargoire, Bayer SAS, 69009 Lyon, France.
Dorme C; Early Discovery, Biochemistry Excellence, Centre de Recherche La Dargoire, Bayer SAS, 69009 Lyon, France.
Paget E; Early Discovery, Biochemistry Excellence, Centre de Recherche La Dargoire, Bayer SAS, 69009 Lyon, France.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 31; Vol. 28 (11). Date of Electronic Publication: 2023 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
RNA, Catalytic*/chemistry
Animals ; Introns/genetics ; Antifungal Agents/pharmacology ; Trans-Splicing ; RNA Splicing
Czasopismo naukowe
Tytuł:
Development of Green and High Throughput Microplate Reader-Assisted Universal Microwell Spectrophotometric Assay for Direct Determination of Tyrosine Kinase Inhibitors in Their Pharmaceutical Formulations Irrespective the Diversity of Their Chemical Structures.
Autorzy:
Darwish IA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Alzoman NZ; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 May 12; Vol. 28 (10). Date of Electronic Publication: 2023 May 12.
Typ publikacji:
Journal Article
MeSH Terms:
Tyrosine Kinase Inhibitors*
High-Throughput Screening Assays*
Drug Compounding ; Spectrophotometry/methods ; Tablets/chemistry
Czasopismo naukowe
Tytuł:
A high throughput bispecific antibody discovery pipeline.
Autorzy:
Segaliny AI; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Jayaraman J; Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA.
Chen X; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Chong J; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Luxon R; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Fung A; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Fu Q; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Jiang X; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Rivera R; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Ma X; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Ren C; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Zimak J; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, CA, 92697, USA.
Hedde PN; Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA.
Shang Y; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA.
Wu G; Amberstone Biosciences, Inc., Irvine, CA, 92618, USA. .
Zhao W; Department of Biomedical Engineering, University of California, Irvine, Irvine, CA, 92697, USA. .; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, CA, 92697, USA. .; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, 92697, USA. .; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA, 92697, USA. .; Edwards Life Sciences Center for Advanced Cardiovascular Technology, University of California, Irvine, Irvine, CA, 92697, USA. .; Department of Biological Chemistry, University of California, Irvine, Irvine, CA, 92697, USA. .; Institute for Immunology, University of California, Irvine, Irvine, CA, 92697, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Apr 07; Vol. 6 (1), pp. 380. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
T-Lymphocytes*
Antibodies, Bispecific*/pharmacology
High-Throughput Screening Assays*
Immunotherapy ; Single-Cell Analysis
Czasopismo naukowe
Tytuł:
The rapid high-throughput screening of ω-transaminases via a colorimetric method using aliphatic α-diketones as amino acceptors.
Autorzy:
Tang K; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Dong J; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Zheng Z; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Zhang T; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Pan H; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
Jia H; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China. .
Li Y; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China. .
Wei P; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 211816, China.
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2023 Apr; Vol. 415 (9), pp. 1733-1740. Date of Electronic Publication: 2023 Feb 25.
Typ publikacji:
Journal Article
MeSH Terms:
Transaminases*/chemistry
Transaminases*/metabolism
High-Throughput Screening Assays*
Colorimetry ; Diacetyl ; Amino Acids ; Amines ; Ketones
Czasopismo naukowe
Tytuł:
Deep-learning image analysis for high-throughput screening of opsono-phagocytosis-promoting monoclonal antibodies against Neisseria gonorrhoeae.
Autorzy:
Vacca F; Monoclonal Antibody Discovery Laboratory, Fondazione Toscana Life Sciences, Siena, Italy.
Cardamone D; Monoclonal Antibody Discovery Laboratory, Fondazione Toscana Life Sciences, Siena, Italy.; Data Science for Health Laboratory, Fondazione Toscana Life Sciences, Siena, Italy.; University of Turin, Turin, Italy.
Andreano E; Monoclonal Antibody Discovery Laboratory, Fondazione Toscana Life Sciences, Siena, Italy.
Medini D; Data Science for Health Laboratory, Fondazione Toscana Life Sciences, Siena, Italy.
Rappuoli R; Fondazione Biotecnopolo Di Siena, Siena, Italy.
Sala C; Monoclonal Antibody Discovery Laboratory, Fondazione Toscana Life Sciences, Siena, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 27; Vol. 14 (1), pp. 4807. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Deep Learning*
Gonorrhea*
Humans ; Neisseria gonorrhoeae ; Antibodies, Monoclonal ; High-Throughput Screening Assays ; Anti-Bacterial Agents/pharmacology ; Phagocytosis
Czasopismo naukowe
Tytuł:
High-throughput screening assay for PARP-HPF1 interaction inhibitors to affect DNA damage repair.
Autorzy:
Dhakar SS; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland.
Galera-Prat A; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland.
Lehtiö L; Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu, Oulu, Finland. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 16; Vol. 14 (1), pp. 3875. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Histones*/drug effects
Histones*/metabolism
Poly(ADP-ribose) Polymerase Inhibitors*/chemistry
Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology
DNA Damage ; DNA Repair ; High-Throughput Screening Assays ; Poly (ADP-Ribose) Polymerase-1/antagonists & inhibitors ; Poly ADP Ribosylation
Czasopismo naukowe
Tytuł:
Development of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes.
Autorzy:
Sakamoto H; Research and Development Headquarters, Well-Being Research Laboratories, Lion Corporation, 100 Tajima, Odawara, Kanagawa, 256-0811, Japan.
Nishikawa M; Research and Development Headquarters, Well-Being Research Laboratories, Lion Corporation, 100 Tajima, Odawara, Kanagawa, 256-0811, Japan.
Yamada S; Research and Development Headquarters, Well-Being Research Laboratories, Lion Corporation, 100 Tajima, Odawara, Kanagawa, 256-0811, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3312. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Tight Junctions*/metabolism
Heparinoids*/metabolism
Humans ; Aged ; Claudin-1/metabolism ; High-Throughput Screening Assays ; Keratinocytes/metabolism ; Claudin-4/metabolism
Czasopismo naukowe
Tytuł:
Current Advances in Japanese Encephalitis Virus Drug Development.
Autorzy:
Guo J; The Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi'an Medical University, Xi'an 710021, China.
Mi Y; The Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi'an Medical University, Xi'an 710021, China.
Guo Y; College of Animal Science and Technology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Bai Y; The Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi'an Medical University, Xi'an 710021, China.
Wang M; Faculty of Life Science and Medicine, University of Science and Technology of China, Hefei 230026, China.
Wang W; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
Wang Y; The Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi'an Medical University, Xi'an 710021, China.
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Źródło:
Viruses [Viruses] 2024 Jan 28; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Encephalitis Virus, Japanese*
Encephalitis, Japanese*/epidemiology
Encephalitis, Viral*
Child ; Animals ; Humans ; High-Throughput Screening Assays ; Drug Development
Czasopismo naukowe
Tytuł:
The Current Situation and Development Prospect of Whole-Genome Screening.
Autorzy:
Yang C; Shanxi Provincial Key Laboratory for Medical Molecular Cell Biology, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education and Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.
Lei Y; Shanxi Provincial Key Laboratory for Medical Molecular Cell Biology, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education and Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.
Ren T; Shanxi Provincial Key Laboratory for Medical Molecular Cell Biology, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education and Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.
Yao M; Shanxi Provincial Key Laboratory for Medical Molecular Cell Biology, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education and Institute of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Endonucleases*
Genetic Testing*
Gene Library ; High-Throughput Screening Assays ; Phenotype
Czasopismo naukowe

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