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    Tytuł:
    A population-based meta-analysis of circulating GFAP for cognition and dementia risk.
    Autorzy:
    Gonzales MM; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
    Wiedner C; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
    Wang CP; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; South Texas Veterans Health Care System, Geriatric Research, Education & Clinical Center, San Antonio, Texas, USA.
    Liu Q; Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
    Bis JC; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.
    Li Z; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.
    Himali JJ; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; The Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Medicine, Boston, Massachusetts, USA.
    Ghosh S; The Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.
    Thomas EA; Brown Foundation of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
    Parent DM; Department of Pathology and Laboratory Medicine, and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
    Kautz TF; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
    Pase MP; The Framingham Heart Study, Framingham, Massachusetts, USA.; School of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria, Australia.; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
    Aparicio HJ; The Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.
    Djoussé L; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Boston Veterans Affairs Healthcare System, Boston, Massachusetts, USA.
    Mukamal KJ; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
    Psaty BM; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, Washington, USA.
    Longstreth WT Jr; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Department of Neurology, University of Washington, Seattle, Washington, USA.
    Mosley TH Jr; The MIND Center, University of Mississippi Medical Center, Jackson, Mississippi, USA.
    Gudnason V; Icelandic Heart Association Research Institute, Kópavogur, Iceland.; Department of Cardiology, University of Iceland, Reykjavik, Iceland.
    Mbangdadji D; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.
    Lopez OL; Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    Yaffe K; Department of Psychiatry, University of California, San Francisco, California, USA.; Department of Neurology, University of California, San Francisco, California, USA.; Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.; San Francisco VA Medical Center, San Francisco, California, USA.
    Sidney S; Kaiser Permanente Medical Center Program, Oakland, California, USA.
    Bryan RN; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    Nasrallah IM; Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    DeCarli CS; Department of Neurology, University of California, Davis, California, USA.
    Beiser AS; The Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Medicine, Boston, Massachusetts, USA.
    Launer LJ; Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.
    Fornage M; Brown Foundation of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
    Tracy RP; Department of Pathology and Laboratory Medicine, and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
    Seshadri S; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Neurology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; The Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.
    Satizabal CL; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.; The Framingham Heart Study, Framingham, Massachusetts, USA.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2022 Oct; Vol. 9 (10), pp. 1574-1585. Date of Electronic Publication: 2022 Sep 03.
    Typ publikacji:
    Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease*
    Dementia*
    Antihypertensive Agents/therapeutic use ; Apolipoproteins ; Cognition ; Glial Fibrillary Acidic Protein ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study.
    Autorzy:
    Lin H; The Framingham Heart Study, Framingham, MA 01701, USA.; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
    Himali JJ; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Public Health, Boston University, Boston, MA 02118, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX 77072, USA.
    Satizabal CL; The Framingham Heart Study, Framingham, MA 01701, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX 77072, USA.
    Beiser AS; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Public Health, Boston University, Boston, MA 02118, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.
    Levy D; The Framingham Heart Study, Framingham, MA 01701, USA.; Population Sciences Branch, National Heart, Lung and Blood Institutes of Health, Bethesda, MD 20824, USA.
    Benjamin EJ; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Public Health, Boston University, Boston, MA 02118, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.
    Gonzales MM; The Framingham Heart Study, Framingham, MA 01701, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX 77072, USA.
    Ghosh S; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.
    Vasan RS; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.
    Seshadri S; The Framingham Heart Study, Framingham, MA 01701, USA.; School of Medicine, Boston University, Boston, MA 02118, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX 77072, USA.
    McGrath ER; The Framingham Heart Study, Framingham, MA 01701, USA.; HRB Clinical Research Facility, National University of Ireland Galway, University Road, H91TK33 Galway, Ireland.
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    Źródło:
    Cells [Cells] 2022 Apr 30; Vol. 11 (9). Date of Electronic Publication: 2022 Apr 30.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Dementia*/diagnosis
    Machine Learning*
    Biomarkers ; Female ; Humans ; Longitudinal Studies ; Male ; Neural Networks, Computer
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Relation of plasma β-amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study.
    Autorzy:
    Romero JR; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; NHLBI's Framingham Heart Study, Framingham, Massachusetts.
    Demissie S; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
    Beiser A; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; NHLBI's Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
    Himali JJ; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; NHLBI's Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
    DeCarli C; Department of Neurology, University of California- Davis, Sacramento, California.
    Levy D; NHLBI's Framingham Heart Study, Framingham, Massachusetts.; The Population Sciences Branch of the National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, Maryland.
    Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; NHLBI's Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Jul; Vol. 7 (7), pp. 1083-1091. Date of Electronic Publication: 2020 Jun 26.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Amyloid beta-Peptides/*blood
    Cerebral Hemorrhage/*blood
    Clusterin/*blood
    tau Proteins/*blood
    Adult ; Aged ; Biomarkers/blood ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circulating ceramide ratios and risk of vascular brain aging and dementia.
    Autorzy:
    McGrath ER; Department of Neurology, Brigham & Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Framingham Heart Study, Framingham, Massachusetts.
    Himali JJ; Framingham Heart Study, Framingham, Massachusetts.; School of Public Health, Boston University, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
    Xanthakis V; Framingham Heart Study, Framingham, Massachusetts.; School of Public Health, Boston University, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Duncan MS; Vanderbilt University Medical Center, Nashville, Tennessee.
    Schaffer JE; Washington University School of Medicine, St Louis, Missouri.
    Ory DS; Washington University School of Medicine, St Louis, Missouri.
    Peterson LR; Washington University School of Medicine, St Louis, Missouri.
    DeCarli C; Department of Neurology, University of California, Davis, California.
    Pase MP; Framingham Heart Study, Framingham, Massachusetts.; Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, Victoria, Australia.; The University of Melbourne, Victoria, Australia.
    Satizabal CL; Framingham Heart Study, Framingham, Massachusetts.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
    Vasan RS; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Beiser AS; Framingham Heart Study, Framingham, Massachusetts.; School of Public Health, Boston University, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Seshadri S; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Feb; Vol. 7 (2), pp. 160-168. Date of Electronic Publication: 2020 Jan 16.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aging/*blood
    Ceramides/*blood
    Dementia/*blood
    Dementia/*epidemiology
    Leukoaraiosis/*blood
    Aged ; Aged, 80 and over ; Alzheimer Disease/blood ; Alzheimer Disease/epidemiology ; Biomarkers/blood ; Cross-Sectional Studies ; Female ; Humans ; Leukoaraiosis/diagnostic imaging ; Leukoaraiosis/pathology ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male ; Massachusetts/epidemiology ; Middle Aged ; Proportional Hazards Models
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Mid-life and late-life vascular risk factor burden and neuropathology in old age.
    Autorzy:
    Conner SC; Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.
    Pase MP; Framingham Heart Study, Framingham, Massachusetts.; Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, Melbourne, Australia.; Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Australia.; Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Australia.
    Carneiro H; Framingham Heart Study, Framingham, Massachusetts.; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
    Raman MR; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
    McKee AC; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; Boston University, Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts.; Department of Veterans Affairs Medical Center, Bedford, Massachusetts.; VA Boston Healthcare System, Boston, Massachusetts.; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts.
    Alvarez VE; Boston University, Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts.; Department of Veterans Affairs Medical Center, Bedford, Massachusetts.; VA Boston Healthcare System, Boston, Massachusetts.; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts.
    Walker JM; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas.
    Satizabal CL; Framingham Heart Study, Framingham, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas.
    Himali JJ; Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas.
    Stein TD; Boston University, Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, Massachusetts.; Department of Veterans Affairs Medical Center, Bedford, Massachusetts.; VA Boston Healthcare System, Boston, Massachusetts.; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts.
    Beiser A; Framingham Heart Study, Framingham, Massachusetts.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
    Seshadri S; Framingham Heart Study, Framingham, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2019 Dec; Vol. 6 (12), pp. 2403-2412. Date of Electronic Publication: 2019 Nov 05.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Tissue Banks*
    Alzheimer Disease/*epidemiology
    Alzheimer Disease/*pathology
    Cerebrovascular Disorders/*epidemiology
    Cerebrovascular Disorders/*pathology
    Aged ; Aged, 80 and over ; Female ; Humans ; Longitudinal Studies ; Male ; Massachusetts/epidemiology ; Middle Aged ; Prognosis ; Risk Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circulating IGFBP-2: a novel biomarker for incident dementia.
    Autorzy:
    McGrath ER; Department of Neurology, Brigham & Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Framingham Heart Study, Framingham, Massachusetts.
    Himali JJ; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Public Health, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Levy D; Framingham Heart Study, Framingham, Massachusetts.; Population Sciences Branch of the National Heart, Lung, Blood Institute of the National Institutes of Health, Bethesda, Maryland.
    Conner SC; Boston University School of Public Health, Boston, Massachusetts.
    DeCarli CS; Department of Neurology, University of California, Davis, California.
    Pase MP; Framingham Heart Study, Framingham, Massachusetts.; Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, Melbourne, Victoria, Australia.; University of Melbourne, Melbourne, Victoria, Australia.
    Courchesne P; Framingham Heart Study, Framingham, Massachusetts.; Population Sciences Branch of the National Heart, Lung, Blood Institute of the National Institutes of Health, Bethesda, Maryland.
    Satizabal CL; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
    Vasan RS; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Beiser AS; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Public Health, Boston, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.
    Seshadri S; Framingham Heart Study, Framingham, Massachusetts.; Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
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    Źródło:
    Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2019 Sep; Vol. 6 (9), pp. 1659-1670. Date of Electronic Publication: 2019 Aug 02.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*diagnosis
    Dementia/*diagnosis
    Insulin-Like Growth Factor Binding Protein 3/*blood
    Aged ; Alzheimer Disease/blood ; Alzheimer Disease/epidemiology ; Biomarkers/blood ; Dementia/blood ; Dementia/epidemiology ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Prospective Studies ; Risk
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study.
    Autorzy:
    Weinstein G; School of Public Health, University of Haifa, Haifa, Israel.
    Davis-Plourde K; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; The Framingham Study, Framingham, Massachusetts.
    Himali JJ; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; The Framingham Study, Framingham, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
    Zelber-Sagi S; School of Public Health, University of Haifa, Haifa, Israel.; Liver Unit, Department of Gastroenterology, Tel-Aviv Medical Center, Tel-Aviv, Israel.
    Beiser AS; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts.; The Framingham Study, Framingham, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.
    Seshadri S; The Framingham Study, Framingham, Massachusetts.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas.
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    Źródło:
    Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2019 Sep; Vol. 39 (9), pp. 1713-1721. Date of Electronic Publication: 2019 Jun 26.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Cognition*
    Cognition Disorders/*epidemiology
    Liver Cirrhosis/*psychology
    Non-alcoholic Fatty Liver Disease/*epidemiology
    Aged ; Cognition Disorders/diagnosis ; Cross-Sectional Studies ; Female ; Humans ; Insulin Resistance ; Linear Models ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/epidemiology ; Male ; Middle Aged ; Non-alcoholic Fatty Liver Disease/diagnosis ; Non-alcoholic Fatty Liver Disease/psychology ; Risk Factors ; Severity of Illness Index ; Tomography, X-Ray Computed
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study.
    Autorzy:
    Salinas J; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; The Henry and Allison McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Lin H; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America.
    Aparico HJ; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
    Huan T; The Framingham Heart Study, Framingham, Massachusetts, United States of America.
    Liu C; The Framingham Heart Study, Framingham, Massachusetts, United States of America.
    Rong J; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.
    Beiser A; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
    Himali JJ; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.
    Freedman JE; Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.
    Larson MG; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America.; Department of Mathematics and Statistics, Boston University, Boston, Massachusetts, United States of America.
    Rosand J; The Henry and Allison McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
    Soreq H; Department of Biological Chemistry, The Life Sciences Institute, The Hebrew University of Jerusalem, Jerusalem, Israel.; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
    Levy D; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; The Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America.
    Seshadri S; The Framingham Heart Study, Framingham, Massachusetts, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, United States of America.
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    Źródło:
    PloS one [PLoS One] 2019 Aug 08; Vol. 14 (8), pp. e0219261. Date of Electronic Publication: 2019 Aug 08 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    MicroRNAs/*genetics
    Stroke/*genetics
    Aged ; Aged, 80 and over ; Brain/metabolism ; Fatty Acid Elongases/genetics ; Fatty Acid Elongases/metabolism ; Female ; Gene Expression Profiling/methods ; Humans ; Longitudinal Studies ; Male ; MicroRNAs/blood ; MicroRNAs/metabolism ; Middle Aged ; Risk Factors ; Transcriptome/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study.
    Autorzy:
    McGrath ER; Department of Neurology, Brigham & Women's Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.; Framingham Heart Study, Framingham, MA, United States of America.
    Himali JJ; Framingham Heart Study, Framingham, MA, United States of America.; Boston University School of Public Health, Boston, MA, United States of America.; Boston University School of Medicine, Boston, MA, United States of America.
    Levy D; Framingham Heart Study, Framingham, MA, United States of America.; Population Sciences Branch, National Heart, Lung and Blood Institutes of Health, Bethesda, MD, United States of America.
    Conner SC; Framingham Heart Study, Framingham, MA, United States of America.; Boston University School of Public Health, Boston, MA, United States of America.
    Pase MP; Framingham Heart Study, Framingham, MA, United States of America.; Melbourne Dementia Research Centre, The Florey Institute for Neuroscience and Mental Health, Victoria, Australia.
    Abraham CR; Boston University School of Medicine, Boston, MA, United States of America.
    Courchesne P; Framingham Heart Study, Framingham, MA, United States of America.
    Satizabal CL; Framingham Heart Study, Framingham, MA, United States of America.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, United States of America.
    Vasan RS; Framingham Heart Study, Framingham, MA, United States of America.; Boston University School of Medicine, Boston, MA, United States of America.
    Beiser AS; Framingham Heart Study, Framingham, MA, United States of America.; Boston University School of Public Health, Boston, MA, United States of America.; Boston University School of Medicine, Boston, MA, United States of America.
    Seshadri S; Framingham Heart Study, Framingham, MA, United States of America.; Boston University School of Medicine, Boston, MA, United States of America.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, United States of America.
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    Źródło:
    PloS one [PLoS One] 2019 Mar 04; Vol. 14 (3), pp. e0213321. Date of Electronic Publication: 2019 Mar 04 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*diagnosis
    Biomarkers/*blood
    Dementia/*diagnosis
    Fibroblast Growth Factors/*blood
    Aged ; Alzheimer Disease/blood ; Alzheimer Disease/epidemiology ; Blood Pressure ; Dementia/blood ; Dementia/epidemiology ; Female ; Fibroblast Growth Factor-23 ; Humans ; Incidence ; Longitudinal Studies ; Male ; Prospective Studies ; Risk Factors ; United States/epidemiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.
    Autorzy:
    Weinstein G; School of Public Health, University of Haifa, Haifa, Israel.
    Davis-Plourde KL; Framingham Heart Study, Framingham, MA, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
    Conner S; Framingham Heart Study, Framingham, MA, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
    Himali JJ; Framingham Heart Study, Framingham, MA, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.
    Beiser AS; Framingham Heart Study, Framingham, MA, United States of America.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.
    Lee A; Department of Epidemiology & Biostatistics, University of California, San Francisco, California, United States of America.
    Rawlings AM; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
    Sedaghat S; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
    Ding J; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America.
    Moshier E; Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
    van Duijn CM; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands.
    Beeri MS; Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel HaShomer, Israel.
    Selvin E; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
    Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands.; Department of Radiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.
    Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, United States of America.
    Haan MN; Department of Epidemiology & Biostatistics, University of California, San Francisco, California, United States of America.
    Seshadri S; Framingham Heart Study, Framingham, MA, United States of America.; Department of Neurology, Boston University School of Medicine, Boston, MA, United States of America.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2019 Feb 15; Vol. 14 (2), pp. e0212293. Date of Electronic Publication: 2019 Feb 15 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Alzheimer Disease/*diagnosis
    Brain/*physiology
    Dementia/*diagnosis
    Hypoglycemic Agents/*therapeutic use
    Insulin/*therapeutic use
    Metformin/*therapeutic use
    Sulfonylurea Compounds/*therapeutic use
    Alzheimer Disease/epidemiology ; Alzheimer Disease/etiology ; Brain/diagnostic imaging ; Cognition/physiology ; Cohort Studies ; Dementia/epidemiology ; Dementia/etiology ; Humans ; Incidence ; Linear Models ; Magnetic Resonance Imaging ; Proportional Hazards Models ; Risk Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study.
    Autorzy:
    Spartano NL; Department of Endocrinology, Diabetes, Nutrition & Weight Management, Boston University School of Medicine (BUSM), Boston, MA, USA.; Framingham Heart Study, Framingham, MA, USA.
    Davis-Plourde KL; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health (BUSPH), Boston, MA, USA.
    Himali JJ; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health (BUSPH), Boston, MA, USA.; Department of Neurology, BUSM, Boston, MA, USA.
    Murabito JM; Framingham Heart Study, Framingham, MA, USA.; Departments of Medicine and Epidemiology, BUSM and BUSPH, Boston, MA, USA.
    Vasan RS; Framingham Heart Study, Framingham, MA, USA.; Departments of Medicine and Epidemiology, BUSM and BUSPH, Boston, MA, USA.
    Beiser AS; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health (BUSPH), Boston, MA, USA.; Department of Neurology, BUSM, Boston, MA, USA.
    Seshadri S; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, BUSM, Boston, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.
    Pokaż więcej
    Źródło:
    Journal of diabetes research [J Diabetes Res] 2019 Jan 09; Vol. 2019, pp. 2718465. Date of Electronic Publication: 2019 Jan 09 (Print Publication: 2019).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Brain-Derived Neurotrophic Factor/*blood
    Diabetes Mellitus/*blood
    Exercise/*physiology
    Insulin-Like Growth Factor I/*metabolism
    Vascular Endothelial Growth Factor A/*blood
    Aged ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Self Report ; Surveys and Questionnaires
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study.
    Autorzy:
    Miller IN; a Department of Psychology , Minneapolis VA Healthcare System , Minneapolis , Minnesota , USA.
    Himali JJ
    Beiser AS
    Murabito JM
    Seshadri S
    Wolf PA
    Au R
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    Źródło:
    Experimental aging research [Exp Aging Res] 2015; Vol. 41 (4), pp. 386-409.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Aging/*psychology
    Cognition/*physiology
    Cognition Disorders/*diagnosis
    Geriatric Assessment/*methods
    Geriatric Assessment/*statistics & numerical data
    Neuropsychological Tests/*statistics & numerical data
    Age Factors ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Humans ; Male ; Massachusetts ; Prospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Framingham Heart Study clock drawing performance: normative data from the offspring cohort.
    Autorzy:
    Nyborn JA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.
    Himali JJ
    Beiser AS
    Devine SA
    Du Y
    Kaplan E
    O'Connor MK
    Rinn WE
    Denison HS
    Seshadri S
    Wolf PA
    Au R
    Pokaż więcej
    Źródło:
    Experimental aging research [Exp Aging Res] 2013; Vol. 39 (1), pp. 80-108.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Cognition*
    Neuropsychological Tests*
    Aging/*psychology
    Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Educational Status ; Female ; Humans ; Male ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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