- Tytuł:
- Nanoencapsulation of MDM2 Inhibitor RG7388 and Class-I HDAC Inhibitor Entinostat Enhances their Therapeutic Potential Through Synergistic Antitumor Effects and Reduction of Systemic Toxicity.
- Autorzy:
- Źródło:
- Molecular pharmaceutics [Mol Pharm] 2024 Mar 04; Vol. 21 (3), pp. 1246-1255. Date of Electronic Publication: 2024 Feb 09.
- Typ publikacji:
- Journal Article
- MeSH Terms:
-
Histone Deacetylase Inhibitors */pharmacologyHistone Deacetylase Inhibitors */therapeutic use
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Benzamides*
Pyridines*
Pyrrolidines*
para-Aminobenzoates*
Humans ; Animals ; Mice ; Tumor Suppressor Protein p53/metabolism ; Apoptosis ; Cell Line, Tumor ; Drug Combinations ; Proto-Oncogene Proteins c-mdm2
Czasopismo naukowe