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    Wyświetlanie 1-13 z 13
    Tytuł:
    A single-cell atlas of conventional central chondrosarcoma reveals the role of endoplasmic reticulum stress in malignant transformation.
    Autorzy:
    Su Z; Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park, New Territories, Hong Kong SAR, China.
    Ho JWK; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park, New Territories, Hong Kong SAR, China.
    Yau RCH; Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Lam YL; Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Shek TWH; Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Yeung MCF; Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Chen H; Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Oreffo ROC; Bone and Joint Research Group, Centre for Human Development, Stem Cells and Regeneration, Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, SO16 6HW, United Kingdom.
    Cheah KSE; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
    Cheung KSC; Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. .
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    Źródło:
    Communications biology [Commun Biol] 2024 Jan 24; Vol. 7 (1), pp. 124. Date of Electronic Publication: 2024 Jan 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Chondrosarcoma*/genetics
    Ascomycota*
    Humans ; Animals ; Mice ; Apoptosis ; Cell Survival ; Disease Models, Animal ; Endoplasmic Reticulum Stress
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Multi-Level Biomarkers for Early Diagnosis of Ischaemic Stroke: A Systematic Review and Meta-Analysis.
    Autorzy:
    Li Q; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Zhao L; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Chan CL; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Zhang Y; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Tong SW; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Zhang X; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Ho JWK; School of Biomedical Sciences, University of Hong Kong, Hong Kong, China.
    Jiao Y; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
    Rainer TH; Department of Emergency Medicine, University of Hong Kong, Hong Kong, China.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Sep 07; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 07.
    Typ publikacji:
    Meta-Analysis; Systematic Review; Journal Article; Review
    MeSH Terms:
    Stroke*/diagnosis
    Brain Ischemia*/diagnosis
    Ischemic Stroke*
    Hemorrhagic Stroke*
    Humans ; Early Diagnosis ; Biomarkers
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Dynamic changes in antibiotic resistance genes and gut microbiota after Helicobacter pylori eradication therapies.
    Autorzy:
    Wang L; Department of Medicine, The University of Hong Kong, Hong Kong, China.
    Yao H; School of Biomedical Science, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health, Hong Kong Science Park, Hong Kong, China.
    Tong T; Department of Medicine, The University of Hong Kong, Hong Kong, China.
    Lau K; Department of Medicine, The University of Hong Kong, Hong Kong, China.
    Leung SY; Centre for PanorOmic Sciences (CPOS), The University of Hong Kong, Hong Kong, China.; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.; The Jockey Club Centre for Clinical Innovation and Discovery, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
    Ho JWK; School of Biomedical Science, The University of Hong Kong, Hong Kong, China.; Laboratory of Data Discovery for Health, Hong Kong Science Park, Hong Kong, China.; Centre for PanorOmic Sciences (CPOS), The University of Hong Kong, Hong Kong, China.
    Leung WK; Department of Medicine, The University of Hong Kong, Hong Kong, China.
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    Źródło:
    Helicobacter [Helicobacter] 2022 Apr; Vol. 27 (2), pp. e12871. Date of Electronic Publication: 2021 Dec 30.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gastrointestinal Microbiome*/genetics
    Helicobacter Infections*/microbiology
    Helicobacter pylori*/genetics
    Amoxicillin/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Clarithromycin/pharmacology ; Clarithromycin/therapeutic use ; Drug Resistance, Microbial ; Drug Therapy, Combination ; Humans
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph.
    Autorzy:
    Du R; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.; Artificial Intelligence Lab, Head Office Information Technology and Health Informatics Division, Hospital Authority, Hong Kong, SAR, China.
    Tsougenis ED; Artificial Intelligence Lab, Head Office Information Technology and Health Informatics Division, Hospital Authority, Hong Kong, SAR, China.
    Ho JWK; The School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
    Chan JKY; Clinical Systems, Information Technology and Health Informatics Division, Hospital Authority, Hong Kong, SAR, China.
    Chiu KWH; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
    Fang BXH; Department of Radiology, Queen Mary Hospital, Hong Kong, SAR, China.
    Ng MY; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.; Department of Medical Imaging, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
    Leung ST; Department of Radiology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, SAR, China.
    Lo CSY; Department of Radiology, Hong Kong Sanatorium & Hospital, Hong Kong, SAR, China.
    Wong HF; Department of Radiology, Queen Mary Hospital, Hong Kong, SAR, China.
    Lam HS; Department of Radiology, Queen Mary Hospital, Hong Kong, SAR, China.
    Chiu LJ; Department of Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, SAR, China.
    So TY; Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
    Wong KT; Department of Imaging and Interventional Radiology, Prince of Wales Hospital, Hong Kong, SAR, China.
    Wong YCI; Department of Radiology, Tuen Muen Hospital, Hong Kong, SAR, China.
    Yu K; Department of Radiology, Tuen Muen Hospital, Hong Kong, SAR, China.
    Yeung YC; Department of Medicine, Princess Margaret Hospital, Hong Kong, SAR, China.
    Chik T; Department of Medicine, Princess Margaret Hospital, Hong Kong, SAR, China.
    Pang JWK; Health Informatics, Information Technology and Health Informatics Division, Hospital Authority, Hong Kong, SAR, China.
    Wai AK; Emergency Medicine Unit, Li Ka Shing, Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
    Kuo MD; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
    Lam TPW; Department of Radiology, Queen Mary Hospital, Hong Kong, SAR, China.
    Khong PL; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
    Cheung NT; Information Technology and Health Informatics Division, Hospital Authority, Hong Kong, SAR, China.
    Vardhanabhuti V; Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China. .
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    Źródło:
    Scientific reports [Sci Rep] 2021 Jul 09; Vol. 11 (1), pp. 14250. Date of Electronic Publication: 2021 Jul 09.
    Typ publikacji:
    Clinical Trial; Journal Article; Multicenter Study
    MeSH Terms:
    COVID-19*/blood
    COVID-19*/diagnostic imaging
    COVID-19 Testing*
    Machine Learning*
    Models, Biological*
    SARS-CoV-2/*metabolism
    Adolescent ; Adult ; Biomarkers/blood ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Thorax/diagnostic imaging
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Randomized, placebo-controlled, double-blind, pilot trial to investigate safety and efficacy of Cerebrolysin in patients with aneurysmal subarachnoid hemorrhage.
    Autorzy:
    Woo PYM; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China. .
    Ho JWK; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Ko NMW; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Li RPT; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Jian L; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Chu ACH; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Kwan MCL; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Chan Y; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Wong AKS; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Wong HT; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Chan KY; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
    Kwok JCK; Department of Neurosurgery, Kwong Wah Hospital, Room CS11-01, 11th Floor, 25 Waterloo Road, Yaumatei, Hong Kong, China.
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    Źródło:
    BMC neurology [BMC Neurol] 2020 Nov 03; Vol. 20 (1), pp. 401. Date of Electronic Publication: 2020 Nov 03.
    Typ publikacji:
    Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial
    MeSH Terms:
    Amino Acids/*therapeutic use
    Brain Ischemia/*epidemiology
    Neuroprotective Agents/*therapeutic use
    Subarachnoid Hemorrhage/*drug therapy
    Adult ; Aged ; Double-Blind Method ; Female ; Glasgow Outcome Scale ; Humans ; Male ; Middle Aged ; Pilot Projects ; Prospective Studies ; Treatment Outcome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer.
    Autorzy:
    Wang Q; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.; Computational Genomics Laboratory, Victor Chang Cardiac Research Institute, Sydney, Australia.
    Ye J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Fang D; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Lv L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Wu W; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Shi D; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Li Y; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Yang L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Bian X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Wu J; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Jiang X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Wang K; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Wang Q; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.
    Hodson MP; Freedman Foundation Metabolomics Facility, Victor Chang Innovation Centre, Victor Chang Cardiac Research Institute, Sydney, Australia.; School of Pharmacy, University of Queensland, Woolloongabba, QLD 4102, Australia.
    Thibaut LM; Computational Genomics Laboratory, Victor Chang Cardiac Research Institute, Sydney, Australia.; School of Mathematics and Statistics, UNSW Sydney, Sydney, Australia.
    Ho JWK; Bioinformatics and Systems Medicine Laboratory, Victor Chang Cardiac Research Institute, Sydney, Australia.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
    Giannoulatou E; Computational Genomics Laboratory, Victor Chang Cardiac Research Institute, Sydney, Australia. .; St Vincent's Clinical School, UNSW Sydney, Sydney, Australia. .
    Li L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. .; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China. .
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    Źródło:
    BMC microbiology [BMC Microbiol] 2020 Apr 23; Vol. 20 (Suppl 1), pp. 83. Date of Electronic Publication: 2020 Apr 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Colorectal Neoplasms/*microbiology
    Gastrointestinal Microbiome/*physiology
    Intestinal Mucosa/*microbiology
    Bacteria/classification ; Bacteria/genetics ; Bacteria/isolation & purification ; Bacteria/metabolism ; Butyrates/metabolism ; Colon/metabolism ; Colon/microbiology ; Colon/pathology ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; DNA Methylation ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic ; Humans ; Intestinal Mucosa/metabolism ; Metabolome ; Reelin Protein ; Transcriptome
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cloud accelerated alignment and assembly of full-length single-cell RNA-seq data using Falco.
    Autorzy:
    Yang A; Victor Chang Cardiac Research Institute, 405 Liverpool St, Darlinghurst, 2010, New South Wales, Australia.; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, 2010, New South Wales, Australia.
    Kishore A; Victor Chang Cardiac Research Institute, 405 Liverpool St, Darlinghurst, 2010, New South Wales, Australia.
    Phipps B; Victor Chang Cardiac Research Institute, 405 Liverpool St, Darlinghurst, 2010, New South Wales, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, 405 Liverpool St, Darlinghurst, 2010, New South Wales, Australia. .; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, 2010, New South Wales, Australia. .; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. .
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    Źródło:
    BMC genomics [BMC Genomics] 2019 Dec 30; Vol. 20 (Suppl 10), pp. 927. Date of Electronic Publication: 2019 Dec 30.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cloud Computing*
    RNA-Seq*
    Single-Cell Analysis*
    Sequence Alignment/*methods
    Exons/genetics ; Humans ; Introns/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A rare cause of sciatica discovered during digital rectal examination: case report of an intrapelvic sciatic notch schwannoma.
    Autorzy:
    Woo PYM; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Ho JMK; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Ho JWK; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Mak CHK; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Wong AKS; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Wong HT; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
    Chan KY; Department of Neurosurgery, Kwong Wah Hospital , Hong Kong , Hong Kong.
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    Źródło:
    British journal of neurosurgery [Br J Neurosurg] 2019 Oct; Vol. 33 (5), pp. 562-565. Date of Electronic Publication: 2017 Sep 14.
    Typ publikacji:
    Case Reports; Journal Article; Video-Audio Media
    MeSH Terms:
    Neurilemmoma/*surgery
    Peripheral Nervous System Neoplasms/*surgery
    Sciatica/*diagnosis
    Adult ; Digital Rectal Examination ; Female ; Humans ; Incidental Findings ; Magnetic Resonance Imaging/methods ; Multimodal Imaging ; Neurilemmoma/complications ; Neurilemmoma/pathology ; Peripheral Nervous System Neoplasms/complications ; Peripheral Nervous System Neoplasms/pathology ; Sciatic Nerve ; Sciatica/surgery ; Tomography, X-Ray Computed
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Enhanced cardiac repair by telomerase reverse transcriptase over-expression in human cardiac mesenchymal stromal cells.
    Autorzy:
    Le TYL; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia.
    Pickett HA; Telomere Length Regulation Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW, 2145, Australia.
    Yang A; Victor Chang Cardiac Research Institute, and St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, and St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
    Thavapalachandran S; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia.; Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.
    Igoor S; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia.
    Yang SF; Telomere Length Regulation Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW, 2145, Australia.
    Farraha M; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia.; Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.
    Voges HK; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, 4072, Australia.
    Hudson JE; School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, 4072, Australia.
    Dos Remedios CG; Department of Anatomy and Histology, School of Medical Sciences, Bosch Institute, The University of Sydney, Sydney, NSW, 2006, Australia.
    Bryan TM; Cell Biology Unit, Children's Medical Research Institute, The University of Sydney, Westmead, NSW, 2145, Australia.
    Kizana E; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia.; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia.; Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia.
    Chong JJH; Centre for Heart Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, 2145, Australia. .; Department of Cardiology, Westmead Hospital, Westmead, NSW, 2145, Australia. .; Sydney Medical School, The University of Sydney, Sydney, NSW, 2006, Australia. .; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia. .
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    Źródło:
    Scientific reports [Sci Rep] 2019 Jul 22; Vol. 9 (1), pp. 10579. Date of Electronic Publication: 2019 Jul 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Mesenchymal Stem Cell Transplantation/*methods
    Mesenchymal Stem Cells/*enzymology
    Myocardial Infarction/*therapy
    Myocytes, Cardiac/*enzymology
    Telomerase/*metabolism
    Animals ; Child ; Humans ; Middle Aged ; Myocytes, Cardiac/transplantation ; Rats ; Receptor, Platelet-Derived Growth Factor alpha/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Dam mutants provide improved sensitivity and spatial resolution for profiling transcription factor binding.
    Autorzy:
    Szczesnik T; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China.
    Sherwood R; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. .; Hubrecht Institute, 3584 CT, Utrecht, The Netherlands. .
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    Źródło:
    Epigenetics & chromatin [Epigenetics Chromatin] 2019 Jun 13; Vol. 12 (1), pp. 36. Date of Electronic Publication: 2019 Jun 13.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Sequence Analysis, DNA/*methods
    Site-Specific DNA-Methyltransferase (Adenine-Specific)/*metabolism
    Transcription Factor 7-Like 2 Protein/*metabolism
    Animals ; Binding Sites ; Chromatin/genetics ; DNA/metabolism ; DNA Methylation/genetics ; DNA-Binding Proteins/metabolism ; Embryonic Stem Cells ; Genomics/methods ; Mice ; Mutation ; Protein Binding ; Site-Specific DNA-Methyltransferase (Adenine-Specific)/genetics ; Transcription Factor 7-Like 2 Protein/genetics ; Transcription Factors/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Ultrafast clustering of single-cell flow cytometry data using FlowGrid.
    Autorzy:
    Ye X; Victor Chang Cardiac Research Institute, Sydney, Australia.; University of New South Wales, Sydney, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, Sydney, Australia. .; University of New South Wales, Sydney, Australia. .; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong. .
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    Źródło:
    BMC systems biology [BMC Syst Biol] 2019 Apr 05; Vol. 13 (Suppl 2), pp. 35. Date of Electronic Publication: 2019 Apr 05.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Flow Cytometry/*methods
    Single-Cell Analysis/*methods
    Algorithms ; Cell Count ; Cluster Analysis ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Identification of active signaling pathways by integrating gene expression and protein interaction data.
    Autorzy:
    Kabir MH; School of Medicine, Western Sydney University, Campbelltown, NSW, Australia.; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.; Department of Computer Science and Engineering, University of Rajshahi, Rajshahi, Bangladesh.
    Patrick R; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.; St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia.; Stem Cells Australia, Melbourne Brain Centre, University of Melbourne, Parkville, VIC, 3010, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. .; St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia. .; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China. .
    O'Connor MD; School of Medicine, Western Sydney University, Campbelltown, NSW, Australia. .; Molecular Medicine Research Group, Western Sydney University, Campbelltown, NSW, Australia. .
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    Źródło:
    BMC systems biology [BMC Syst Biol] 2018 Dec 31; Vol. 12 (Suppl 9), pp. 120. Date of Electronic Publication: 2018 Dec 31.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Protein Interaction Maps*
    Transcriptome*
    Computational Biology/*methods
    Signal Transduction/*genetics
    Animals ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Lens, Crystalline/cytology ; Lens, Crystalline/metabolism ; Mice ; Tooth/cytology ; Tooth/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Discovery of cell-type specific DNA motif grammar in cis-regulatory elements using random Forest.
    Autorzy:
    Wang X; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
    Lin P; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia.
    Ho JWK; Victor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia. j.ho@victorchang.edu.au.; St. Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW, 2010, Australia. j.ho@victorchang.edu.au.
    Pokaż więcej
    Źródło:
    BMC genomics [BMC Genomics] 2018 Jan 19; Vol. 19 (Suppl 1), pp. 929. Date of Electronic Publication: 2018 Jan 19.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Algorithms*
    Nucleotide Motifs*
    Regulatory Elements, Transcriptional*
    Computational Biology/*methods
    Neoplasms/*genetics
    Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/classification ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasms/classification ; Software ; Transcription Factor 7-Like 2 Protein/classification ; Transcription Factor 7-Like 2 Protein/genetics ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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